William N. Zagotta - Related publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
ion channels
Website:
http://depts.washington.edu/pbiopage/faculty/wzagotta
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Guan W, Stephens RF, Mourad O, Mehta A, Fux J, Spafford JD. Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404. PMID 32710088 DOI: 10.1038/s41598-020-69197-3   
2020 Schlegel AM, Haswell ES. Analyzing plant mechanosensitive ion channels expressed in giant E. coli spheroplasts by single-channel patch-clamp electrophysiology. Methods in Cell Biology. 160: 61-82. PMID 32896333 DOI: 10.1016/bs.mcb.2020.02.007   
2020 Mony L, Stroebel D, Isacoff EY. Dimer interaction in the Hv1 proton channel. Proceedings of the National Academy of Sciences of the United States of America. PMID 32788354 DOI: 10.1073/pnas.2010032117   
2020 Codding SJ, Johnson AA, Trudeau MC. Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains. Channels (Austin, Tex.). 14: 294-309. PMID 32924766 DOI: 10.1080/19336950.2020.1816107   
2020 Diniz AFA, Ferreira RC, de Souza ILL, da Silva BA. Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review. Frontiers in Pharmacology. 11: 1120. PMID 32848741 DOI: 10.3389/fphar.2020.01120   
2020 Deng Z, Maksaev G, Schlegel AM, Zhang J, Rau M, Fitzpatrick JAJ, Haswell ES, Yuan P. Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance. Nature Communications. 11: 3690. PMID 32704140 DOI: 10.1038/s41467-020-17538-1   
2020 Huffer KE, Aleksandrova AA, Jara-Oseguera A, Forrest LR, Swartz KJ. Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms. Elife. 9. PMID 32804077 DOI: 10.7554/eLife.58660   
2020 Han Y, Li T, Wang S, Chen J. A Flow-Measuring Algorithm of Arc-Bottomed Open Channels through Multiple Characteristic Sensing Points of the Flow-Velocity Sensor in Agricultural Irrigation Areas. Sensors (Basel, Switzerland). 20. PMID 32806577 DOI: 10.3390/s20164504   
2020 Nam YW, Cui M, Orfali R, Viegas A, Nguyen M, Mohammed EHM, Zoghebi KA, Rahighi S, Parang K, Zhang M. Hydrophobic interactions between the HA helix and S4-S5 linker modulate apparent Ca sensitivity of SK2 channels. Acta Physiologica (Oxford, England). e13552. PMID 32865319 DOI: 10.1111/apha.13552   
2020 Kim DH, Park WH, Oh HG, Jeon DC, Lim JM, Song KS. Two-Channel Graphene pH Sensor Using Semi-Ionic Fluorinated Graphene Reference Electrode. Sensors (Basel, Switzerland). 20. PMID 32731474 DOI: 10.3390/s20154184   
2020 Cardoso FC, Marliac MA, Geoffroy C, Schmit M, Bispat A, Lewis RJ, Tuck KL, Duggan PJ. The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. Bioorganic & Medicinal Chemistry. 28: 115655. PMID 32828422 DOI: 10.1016/j.bmc.2020.115655   
2020 Kim JH, Won J, Oh SB. Expression of Ca3.1 T-type Calcium Channels in Acutely Isolated Adult Rat Odontoblasts. Archives of Oral Biology. 118: 104864. PMID 32847753 DOI: 10.1016/j.archoralbio.2020.104864   
2020 Hong L, Zhang M, Sridhar A, Darbar D. Pathogenic mutations perturb calmodulin regulation of Na1.8 channel. Biochemical and Biophysical Research Communications. PMID 32948286 DOI: 10.1016/j.bbrc.2020.08.010   
2020 López-Vera E, Martínez-Hernández L, Aguilar MB, Carrillo E, Gajewiak J. Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes. Marine Drugs. 18. PMID 32823677 DOI: 10.3390/md18080425   
2020 Kim JM, Song KS, Xu B, Wang T. Role of potassium channels in female reproductive system. Obstetrics & Gynecology Science. PMID 32838485 DOI: 10.5468/ogs.20064   
2020 Burton MJ, Cresser-Brown J, Thomas M, Portolano N, Basran J, Freeman SL, Kwon H, Bottrill AR, Llansola-Portoles MJ, Pascal AA, Jukes-Jones R, Chernova T, Schmid R, Davies NW, Storey NM, et al. Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. The Journal of Biological Chemistry. PMID 32723862 DOI: 10.1074/jbc.RA120.014150   
2020 Morán-Zendejas R, Delgado-Ramírez M, Xu J, Valdés-Abadía B, Aréchiga-Figueroa IA, Cui M, Rodríguez-Menchaca AA. In vitro and in silico characterization of the inhibition of Kir4.1 channels by aminoglycoside antibiotics. British Journal of Pharmacology. PMID 32726456 DOI: 10.1111/bph.15214   
2020 Cherny VV, Musset B, Morgan D, Thomas S, Smith SME, DeCoursey TE. Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel. The Journal of General Physiology. 152. PMID 32902579 DOI: 10.1085/jgp.202012664   
2020 Brauchi SE, Rothberg BS. Gating and calcium-sensing mechanisms of TRPA1 channels revealed. Cell Calcium. 91: 102278. PMID 32858446 DOI: 10.1016/j.ceca.2020.102278   
2020 Chen LC, Zheng J, Liu J, Gong XT, Chen ZZ, Guo RX, Huang X, Zhang YP, Zhang L, Li R, Shao X, Hong W, Zhang HL. Nonadditive Transport in Multi-Channel Single-Molecule Circuits. Small (Weinheim An Der Bergstrasse, Germany). e2002808. PMID 32851802 DOI: 10.1002/smll.202002808   
2020 Ma Y, Luo Q, Fu J, Che Y, Guo F, Mei L, Zhang Q, Li Y, Yang H. Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating. Journal of Medicinal Chemistry. PMID 32877186 DOI: 10.1021/acs.jmedchem.0c00842   
2020 Díaz-Franulic I, Raddatz N, Castillo K, González-Nilo FD, Latorre R. A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747539 DOI: 10.1073/pnas.2004303117   
2020 Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. The T-type calcium channel isoform Ca3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile. British Journal of Anaesthesia. PMID 32859366 DOI: 10.1016/j.bja.2020.07.022   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Xie Z, Zhao Y, Yang W, Li W, Wu Y, Chen Z. Methotrexate, a small molecular scaffold targeting Kv1.3 channel extracellular pore region. Biochemical and Biophysical Research Communications. PMID 32863001 DOI: 10.1016/j.bbrc.2020.08.050   
2020 Zheng SP, Jiang JJ, van der Lee A, Barboiu M. Voltage-responsive synthetic Cl--channel regulated by pH. Angewandte Chemie (International Ed. in English). PMID 32820831 DOI: 10.1002/anie.202008393   
2020 Niu Y, Tao X, Touhara KK, MacKinnon R. Cryo-EM analysis of PIP regulation in mammalian GIRK channels. Elife. 9. PMID 32844743 DOI: 10.7554/eLife.60552   
2020 van der Horst J, Greenwood IA, Jepps TA. Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels. Frontiers in Physiology. 11: 727. PMID 32695022 DOI: 10.3389/fphys.2020.00727   
2020 Mondéjar-Parreño G, Barreira B, Callejo M, Morales-Cano D, Barrese V, Esquivel-Ruiz S, Olivencia MA, Macías M, Moreno L, Greenwood IA, Perez-Vizcaino F, Cogolludo A. Uncovered Contribution of Kv7 Channels to Pulmonary Vascular Tone in Pulmonary Arterial Hypertension. Hypertension (Dallas, Tex. : 1979). 76: 1134-1146. PMID 32829658 DOI: 10.1161/HYPERTENSIONAHA.120.15221   
2020 Sherikar AS, Bhatia MS, Dhavale RP. Identification and Investigation of Chalcone Derivatives as Calcium Channel Blockers: Pharmacophore modeling, Docking studies, In-vitro screening, and 3D-QSAR Analysis. Current Computer-Aided Drug Design. PMID 32664842 DOI: 10.2174/1573409916666200714143930   
2020 Cooper G, Kang S, Perez-Rosello T, Guzman JN, Galtieri D, Xie Z, Kondapalli J, Mordell J, Silverman RB, Surmeier DJ. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca1.3 L-Type Calcium Channels. Acs Chemical Biology. PMID 32881483 DOI: 10.1021/acschembio.0c00577   
2020 Rose P, Schleimer JH, Schreiber S. Modifications of sodium channel voltage dependence induce arrhythmia-favouring dynamics of cardiac action potentials. Plos One. 15: e0236949. PMID 32750067 DOI: 10.1371/journal.pone.0236949   
2020 Zhang Q, Si Y, Yang L, Wang L, Peng S, Chen Y, Chen M, Zhou X, Liu Z. Two Novel Peptide Toxins from the Spider Inhibit Tetrodotoxin-Sensitive Sodium Channels. Toxins. 12. PMID 32824960 DOI: 10.3390/toxins12090529   
2020 Capatina AL, Lagos D, Brackenbury WJ. Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges. Reviews of Physiology, Biochemistry and Pharmacology. PMID 32865696 DOI: 10.1007/112_2020_46   
2020 Lei J, Liu X, Song M, Zhou Y, Fan J, Shen X, Xu X, Kapoor I, Zhu G, Wang J. Aberrant Exon 8/8a Splicing by Downregulated PTBP (Polypyrimidine Tract-Binding Protein)-1 Increases Ca1.2 Dihydropyridine Resistance to Attenuate Vasodilation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315010. PMID 32787518 DOI: 10.1161/ATVBAHA.120.315010   
2020 Thorington GU, Hessinger DA. Activated L-Type Calcium Channels Inhibit Chemosensitized Nematocyst Discharge from Sea Anemone Tentacles. The Biological Bulletin. 238: 180-192. PMID 32597714 DOI: 10.1086/708947   
2020 Himmel NJ, Cox DN. Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature. Proceedings. Biological Sciences. 287: 20201309. PMID 32842926 DOI: 10.1098/rspb.2020.1309   
2020 Milenkovic S, Bodrenko IV, Lagostena L, Gradogna A, Serra G, Bosin A, Carpaneto A, Ceccarelli M. The mechanism and energetics of a ligand-controlled hydrophobic gate in a mammalian two pore channel. Physical Chemistry Chemical Physics : Pccp. 22: 15664-15674. PMID 32618303 DOI: 10.1039/d0cp00805b   
2020 Frankel EB, Kurshan PT. All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation. Neuron. 107: 593-594. PMID 32818471 DOI: 10.1016/j.neuron.2020.07.028   
2020 Kimoto T, Suzuki K, Fukuda T, Emoto A. An on-demand bench-top fabrication process for fluidic chips based on cross-diffusion through photopolymerization. Biomicrofluidics. 14: 044104. PMID 32699564 DOI: 10.1063/5.0014956   
2020 Cottone G, Chiodo L, Maragliano L. Thermodynamics and Kinetics of Ion Permeation in Wild-Type and Mutated Open Active Conformation of the Human α7 Nicotinic Receptor. Journal of Chemical Information and Modeling. PMID 32803965 DOI: 10.1021/acs.jcim.0c00549   
2020 Williams I, Brunton E, Rapeaux A, Liu Y, Luan S, Nazarpour K, Constandinou T. SenseBack - An Implantable System for Bidirectional Neural Interfacing. Ieee Transactions On Biomedical Circuits and Systems. PMID 32915746 DOI: 10.1109/TBCAS.2020.3022839   
2020 Charlton FW, Pearson HM, Hover S, Lippiat JD, Fontana J, Barr JN, Mankouri J. Ion Channels as Therapeutic Targets for Viral Infections: Further Discoveries and Future Perspectives. Viruses. 12. PMID 32756358 DOI: 10.3390/v12080844   
2020 Si M, Andler J, Lyu X, Niu C, Datta S, Agrawal R, Ye PD. Indium-Tin-Oxide Transistors with One Nanometer Thick Channel and Ferroelectric Gating. Acs Nano. PMID 32833445 DOI: 10.1021/acsnano.0c03978   
2020 Boente-Juncal A, Raposo-Garcia S, Costas C, Louzao MC, Vale C, Botana LM. Partial blockade of human voltage-dependent sodium channels by the marine toxins azaspiracids. Chemical Research in Toxicology. PMID 32872774 DOI: 10.1021/acs.chemrestox.0c00216   
2020 Cobo R, García-Piqueras J, García-Mesa Y, Feito J, García-Suárez O, Vega JA. Peripheral Mechanobiology of Touch-Studies on Vertebrate Cutaneous Sensory Corpuscles. International Journal of Molecular Sciences. 21. PMID 32867400 DOI: 10.3390/ijms21176221   
2020 Encinas AC, Watkins JC, Longoria IA, Johnson JP, Hammer MF. Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy. Plos One. 15: e0238121. PMID 32845893 DOI: 10.1371/journal.pone.0238121   
2020 Rahban R, Nef S. CatSper: The complex main gate of calcium entry in mammalian spermatozoa. Molecular and Cellular Endocrinology. 110951. PMID 32712386 DOI: 10.1016/j.mce.2020.110951