| Year |
Citation |
Score |
| 2023 |
López-Tena M, Farrera-Soler L, Barluenga S, Winssinger N. Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection). Jacs Au. 3: 449-458. PMID 36873687 DOI: 10.1021/jacsau.2c00588 |
0.708 |
|
| 2022 |
Patouret R, Barluenga S, Winssinger N. Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication. Bioorganic & Medicinal Chemistry. 69: 116883. PMID 35772286 DOI: 10.1016/j.bmc.2022.116883 |
0.706 |
|
| 2022 |
Farrera-Soler L, Gonse A, Kim KT, Barluenga S, Winssinger N. Combining recombinase polymerase amplification and DNA-templated reaction for SARS-CoV-2 sensing with dual fluorescence and lateral flow assay output. Biopolymers. e23485. PMID 35023571 DOI: 10.1002/bip.23485 |
0.717 |
|
| 2021 |
Vummidi BR, Farrera-Soler L, Daguer JP, Dockerill M, Barluenga S, Winssinger N. A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules. Nature Chemistry. PMID 34873299 DOI: 10.1038/s41557-021-00829-5 |
0.81 |
|
| 2021 |
Sabale PM, Imiołek M, Raia P, Barluenga S, Winssinger N. Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries. Journal of the American Chemical Society. 143: 18932-18940. PMID 34739233 DOI: 10.1021/jacs.1c07013 |
0.718 |
|
| 2021 |
Pagano S, Yerly S, Meyer B, Juillard C, Suh N, Le Terrier C, Daguer JP, Farrera-Soler L, Barluenga S, Piumatti G, Hartley O, Lemaitre B, Eberhardt CS, Siegrist CA, Eckerle I, ... ... Winssinger N, et al. SARS-CoV2- infection as a trigger of humoral response against apolipoprotein A-1. European Journal of Clinical Investigation. e13661. PMID 34324704 DOI: 10.1111/eci.13661 |
0.768 |
|
| 2021 |
Liu W, Patouret R, Barluenga S, Plank M, Loewith R, Winssinger N. Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides. Acs Central Science. 7: 954-962. PMID 34235256 DOI: 10.1021/acscentsci.1c00056 |
0.756 |
|
| 2021 |
Daguer JP, Gonse A, Shchukin Y, Farrera-Soler L, Barluenga S, Winssinger N. Dual Bcl-X /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy. Bioorganic & Medicinal Chemistry. 44: 116282. PMID 34216984 DOI: 10.1016/j.bmc.2021.116282 |
0.809 |
|
| 2021 |
Farrera-Soler L, Daguer JP, Barluenga S, Winssinger N. Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2. Chimia. 75: 276-284. PMID 33902795 DOI: 10.2533/chimia.2021.276 |
0.77 |
|
| 2020 |
Farrera-Soler L, Daguer JP, Barluenga S, Vadas O, Cohen P, Pagano S, Yerly S, Kaiser L, Vuilleumier N, Winssinger N. Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma. Plos One. 15: e0238089. PMID 32903266 DOI: 10.1371/Journal.Pone.0238089 |
0.768 |
|
| 2020 |
Streuff J, Echavarren AM, González JM, Oestreich M, Gansäuer A, Barluenga S, Winssinger N. Kilian Muñiz (1970-2020). Angewandte Chemie (International Ed. in English). PMID 32249993 DOI: 10.1002/Anie.202004481 |
0.702 |
|
| 2020 |
Farrera-Soler L, Daguer JP, Raunft P, Barluenga S, Imberty A, Winssinger N. PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins. Bioorganic & Medicinal Chemistry. 115458. PMID 32241620 DOI: 10.1016/J.Bmc.2020.115458 |
0.806 |
|
| 2020 |
López-Andarias J, Saarbach J, Moreau D, Cheng Y, Derivery E, Laurent Q, González-Gaitán M, Winssinger N, Sakai N, Matile S. Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks. Journal of the American Chemical Society. PMID 32109058 DOI: 10.1021/Jacs.9B13621 |
0.309 |
|
| 2020 |
Saarbach J, Barluenga S, Winssinger N. PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries. Methods in Molecular Biology (Clifton, N.J.). 2105: 119-139. PMID 32088867 DOI: 10.1007/978-1-0716-0243-0_7 |
0.767 |
|
| 2019 |
Figuerola-Conchas A, Saarbach J, Daguer JP, Cieren A, Barluenga S, Winssinger N, Gotta M. Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions. Acs Chemical Biology. PMID 31790201 DOI: 10.1021/Acschembio.9B00832 |
0.778 |
|
| 2019 |
Laurent Q, Berthet M, Cheng Y, Sakai N, Barluenga S, Winssinger N, Matile S. Probing for Thiol-Mediated Uptake into Bacteria. Chembiochem : a European Journal of Chemical Biology. PMID 31603284 DOI: 10.1002/Cbic.201900378 |
0.701 |
|
| 2019 |
Saarbach J, Sabale PM, Winssinger N. Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics. Current Opinion in Chemical Biology. 52: 112-124. PMID 31541865 DOI: 10.1016/J.Cbpa.2019.06.006 |
0.354 |
|
| 2019 |
Kim KT, Angerani S, Chang D, Winssinger N. Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules. Journal of the American Chemical Society. PMID 31538784 DOI: 10.1021/Jacs.9B05688 |
0.345 |
|
| 2019 |
Chang D, Lindberg E, Feng S, Angerani S, Riezman H, Winssinger N. Luciferase-Induced Photouncaging: Bioluminolysis. Angewandte Chemie (International Ed. in English). PMID 31478317 DOI: 10.1002/Anie.201907734 |
0.323 |
|
| 2019 |
Galli V, Sadhu KK, Masi D, Saarbach J, Roux A, Winssinger N. Caprin‐1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence Discrimination Helvetica Chimica Acta. 103. DOI: 10.1002/Hlca.201900255 |
0.708 |
|
| 2018 |
Anzola M, Winssinger N. Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated Ligation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30451338 DOI: 10.1002/Chem.201804283 |
0.341 |
|
| 2018 |
Payne RJ, Winssinger N. Editorial overview: Synthetic biomolecules. Current Opinion in Chemical Biology. PMID 30201441 DOI: 10.1016/J.Cbpa.2018.08.005 |
0.325 |
|
| 2018 |
Saarbach J, Lindberg E, Winssinger N. Ruthenium-based Photocatalysis in Templated Reactions. Chimia. 72: 207-211. PMID 29720310 DOI: 10.2533/Chimia.2018.207 |
0.303 |
|
| 2018 |
Sayers J, Payne RJ, Winssinger N. Peptide nucleic acid-templated selenocystine-selenoester ligation enables rapid miRNA detection. Chemical Science. 9: 896-903. PMID 29629156 DOI: 10.1039/C7Sc02736B |
0.324 |
|
| 2018 |
Lagoutte R, Pastor M, Berthet M, Winssinger N. Rapid and scalable synthesis of chiral bromolactones as precursors to α-exo-methylene-γ-butyrolactone-containing sesquiterpene lactones Tetrahedron. 74: 6012-6021. DOI: 10.1016/J.Tet.2018.08.045 |
0.804 |
|
| 2017 |
Chang D, Kim KT, Lindberg E, Winssinger N. Accelerating Turnover Frequency in Nucleic Acid Templated Reactions. Bioconjugate Chemistry. PMID 29178795 DOI: 10.1021/Acs.Bioconjchem.7B00663 |
0.335 |
|
| 2017 |
Lagoutte R, Serba C, Winssinger N. Synthesis of deoxyelephantopin analogues. The Journal of Antibiotics. PMID 29089602 DOI: 10.1038/Ja.2017.132 |
0.782 |
|
| 2017 |
Lagoutte R, Winssinger N. Following the Lead from Nature with Covalent Inhibitors. Chimia. 71: 703-711. PMID 29070414 DOI: 10.2533/Chimia.2017.703 |
0.804 |
|
| 2017 |
Saarbach J, Lindberg E, Folliet S, Georgeon S, Hantschel O, Winssinger N. Kinase-templated abiotic reaction. Chemical Science. 8: 5119-5125. PMID 28970898 DOI: 10.1039/C7Sc01416C |
0.335 |
|
| 2017 |
Saarbach J, Masi D, Zambaldo C, Winssinger N. Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization. Bioorganic & Medicinal Chemistry. PMID 28624242 DOI: 10.1016/J.Bmc.2017.05.064 |
0.816 |
|
| 2017 |
Lagoutte R, Patouret R, Winssinger N. Covalent inhibitors: an opportunity for rational target selectivity. Current Opinion in Chemical Biology. 39: 54-63. PMID 28609675 DOI: 10.1016/J.Cbpa.2017.05.008 |
0.807 |
|
| 2017 |
Machida T, Novoa A, Gillon É, Zheng S, Claudinon J, Eierhoff T, Imberty A, Römer W, Winssinger N. Dynamic Cooperative Glycan Assembly Blocks the Binding of Bacterial Lectins to Epithelial Cells. Angewandte Chemie (International Ed. in English). PMID 28504473 DOI: 10.1002/Anie.201700813 |
0.778 |
|
| 2017 |
Chang D, Lindberg E, Winssinger N. Critical Analysis of Rate Constants and Turnover Frequency in Nucleic Acid-Templated Reactions: Reaching Terminal Velocity. Journal of the American Chemical Society. PMID 28099008 DOI: 10.1021/Jacs.6B12764 |
0.344 |
|
| 2016 |
Lagoutte R, Serba C, Abegg D, Hoch DG, Adibekian A, Winssinger N. Divergent synthesis and identification of the cellular targets of deoxyelephantopins. Nature Communications. 7: 12470. PMID 27539788 DOI: 10.1038/Ncomms12470 |
0.793 |
|
| 2016 |
Holtzer L, Oleinich I, Anzola M, Lindberg E, Sadhu KK, Gonzalez-Gaitan M, Winssinger N. Nucleic Acid Templated Chemical Reaction in a Live Vertebrate. Acs Central Science. 2: 394-400. PMID 27413783 DOI: 10.1021/Acscentsci.6B00054 |
0.698 |
|
| 2016 |
Machida T, Dutt S, Winssinger N. Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization. Angewandte Chemie (International Ed. in English). PMID 27320214 DOI: 10.1002/Anie.201602751 |
0.309 |
|
| 2016 |
Machida T, Winssinger N. One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell Compatible Chelation-Assisted CuAAC Conjugation. Chembiochem : a European Journal of Chemical Biology. PMID 26852736 DOI: 10.1002/Cbic.201600003 |
0.303 |
|
| 2016 |
Versele M, Haefner B, Wroblowski B, Stansfield I, Mevellec L, Gilissen R, Neumann L, Augustin M, Jacobs K, Cools J, Barluenga S, Röthlingshöfer M, Karthikeyan G, Attar R, Meerpoel L, ... Winssinger N, et al. Abstract 4800: Covalent Flt3-Cys828 inhibition represents a novel therapeutic approach for the treatment of Flt3-ITD and Flt3-D835 mutant acute myeloid leukemia Cancer Research. 76: 4800-4800. DOI: 10.1158/1538-7445.Am2016-4800 |
0.79 |
|
| 2016 |
Zambaldo C, Daguer J, Saarbach J, Barluenga S, Winssinger N. Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties Medchemcomm. 7: 1340-1351. DOI: 10.1039/C6Md00242K |
0.799 |
|
| 2016 |
Serba C, Lagoutte R, Winssinger N. Rapid and Scalable Synthesis of cis-Fused Guaiane-Type Sesquiterpenes European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.201501277 |
0.79 |
|
| 2015 |
Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules. Chemical Science. 6: 739-744. PMID 30154995 DOI: 10.1039/C4Sc01654H |
0.812 |
|
| 2015 |
Barluenga S, Zambaldo C, Ioannidou HA, Ciobanu M, Morieux P, Daguer JP, Winssinger N. Novel PTP1B inhibitors identified by DNA display of fragment pairs. Bioorganic & Medicinal Chemistry Letters. PMID 26691757 DOI: 10.1016/J.Bmcl.2015.11.102 |
0.792 |
|
| 2015 |
Viéville JM, Barluenga S, Winssinger N, Delsuc MA. Duplex formation and secondary structure of γ-PNA observed by NMR and CD. Biophysical Chemistry. PMID 26493008 DOI: 10.1016/J.Bpc.2015.09.002 |
0.731 |
|
| 2015 |
Sadhu KK, Lindberg E, Winssinger N. In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis. Chemical Communications (Cambridge, England). PMID 26426098 DOI: 10.1039/C5Cc05405B |
0.673 |
|
| 2015 |
Novoa A, Winssinger N. DNA display of glycoconjugates to emulate oligomeric interactions of glycans. Beilstein Journal of Organic Chemistry. 11: 707-19. PMID 26113879 DOI: 10.3762/Bjoc.11.81 |
0.793 |
|
| 2015 |
Barluenga S, Winssinger N. PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions. Accounts of Chemical Research. 48: 1319-31. PMID 25947113 DOI: 10.1021/Acs.Accounts.5B00109 |
0.77 |
|
| 2015 |
Machida T, Lang K, Xue L, Chin JW, Winssinger N. Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne. Bioconjugate Chemistry. 26: 802-6. PMID 25897481 DOI: 10.1021/Acs.Bioconjchem.5B00101 |
0.552 |
|
| 2015 |
Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules. Angewandte Chemie (International Ed. in English). 54: 6057-61. PMID 25772490 DOI: 10.1002/Anie.201412276 |
0.788 |
|
| 2015 |
Zambaldo C, Barluenga S, Winssinger N. PNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 8-15. PMID 25621730 DOI: 10.1016/J.Cbpa.2015.01.005 |
0.818 |
|
| 2015 |
Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules Chemical Science. 6: 739-744. DOI: 10.1039/c4sc01654h |
0.791 |
|
| 2015 |
Daguer J, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identifizierung von niedermolekularen kovalenten Bromodomäne-Bindern aus einer DNA-kodierten Bibliothek Angewandte Chemie. 127: 6155-6159. DOI: 10.1002/Ange.201412276 |
0.754 |
|
| 2014 |
Novoa A, Machida T, Barluenga S, Imberty A, Winssinger N. PNA-encoded synthesis (PES) of a 10 000-member hetero-glycoconjugate library and microarray analysis of diverse lectins. Chembiochem : a European Journal of Chemical Biology. 15: 2058-65. PMID 25158314 DOI: 10.1002/Cbic.201402280 |
0.805 |
|
| 2014 |
Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N. A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa. Angewandte Chemie (International Ed. in English). 53: 8885-9. PMID 25044671 DOI: 10.1002/Anie.201402831 |
0.775 |
|
| 2014 |
Gorska K, Winssinger N. Rapid miRNA imaging in cells using fluorogenic templated Staudinger reaction between PNA-based probes. Methods in Molecular Biology (Clifton, N.J.). 1050: 179-92. PMID 24297360 DOI: 10.1007/978-1-62703-553-8_15 |
0.647 |
|
| 2014 |
Winssinger N, Gorska K, Ciobanu M, Daguer JP, Barluenga S. Assembly of PNA-tagged small molecules, peptides, and carbohydrates onto DNA templates: programming the combinatorial pairing and inter-ligand distance. Methods in Molecular Biology (Clifton, N.J.). 1050: 95-110. PMID 24297353 DOI: 10.1007/978-1-62703-553-8_8 |
0.797 |
|
| 2014 |
Duplan V, Serba C, Garcia J, Valot G, Barluenga S, Hoerlé M, Cuendet M, Winssinger N. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway. Organic & Biomolecular Chemistry. 12: 370-5. PMID 24263232 DOI: 10.1039/C3Ob42049C |
0.803 |
|
| 2013 |
Sadhu KK, Winssinger N. Nucleic acid-tagged peptides: encoding libraries and controlling dimerization and conformation. Chimia. 67: 905-9. PMID 24594336 DOI: 10.2533/Chimia.2013.905 |
0.723 |
|
| 2013 |
Barluenga S, Winssinger N. Picture perfect: DNA-templated photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 14: 1927-8. PMID 24006240 DOI: 10.1002/Cbic.201300416 |
0.749 |
|
| 2013 |
Novoa A, Barluenga S, Serba C, Winssinger N. Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates. Chemical Communications (Cambridge, England). 49: 7608-10. PMID 23882465 DOI: 10.1039/C3Cc43458C |
0.783 |
|
| 2013 |
Winssinger N. Nucleic acid-programmed assemblies: translating instruction into function in chemical biology. Chimia. 67: 340-8. PMID 23863269 DOI: 10.2533/Chimia.2013.340 |
0.375 |
|
| 2013 |
Gorska K, Winssinger N. Reactions templated by nucleic acids: more ways to translate oligonucleotide-based instructions into emerging function. Angewandte Chemie (International Ed. in English). 52: 6820-43. PMID 23794204 DOI: 10.1002/Anie.201208460 |
0.656 |
|
| 2013 |
Sadhu KK, Winssinger N. Detection of miRNA in live cells by using templated RuII-catalyzed unmasking of a fluorophore. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 8182-9. PMID 23633397 DOI: 10.1002/Chem.201300060 |
0.695 |
|
| 2013 |
Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Self-assembled antibody multimers through peptide nucleic acid conjugation. Journal of the American Chemical Society. 135: 340-6. PMID 23210862 DOI: 10.1021/Ja309505C |
0.778 |
|
| 2013 |
Zambaldo C, Sadhu KK, Karthikeyan G, Barluenga S, Daguer JP, Winssinger N. Selective affinity-based probe for oncogenic kinases suitable for live cell imaging Chemical Science. 4: 2088-2092. DOI: 10.1039/C3Sc21856B |
0.785 |
|
| 2013 |
Sadhu KK, Röthlingshöfer M, Winssinger N. DNA as a platform to program assemblies with emerging functions in chemical biology Israel Journal of Chemistry. 53: 75-86. DOI: 10.1002/ijch.201200100 |
0.663 |
|
| 2013 |
Serba C, Winssinger N. Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis (Eur. J. Org. Chem. 20/2013) European Journal of Organic Chemistry. 2013: n/a-n/a. DOI: 10.1002/Ejoc.201390055 |
0.799 |
|
| 2013 |
Serba C, Winssinger N. Following the lead from nature: Divergent pathways in natural product synthesis and diversity-oriented synthesis European Journal of Organic Chemistry. 4195-4214. DOI: 10.1002/Ejoc.201300201 |
0.805 |
|
| 2013 |
Gorska K, Winssinger N. Reaktionen an Nucleinsäuretemplaten: mehr Methoden zur Übersetzung Oligonucleotid-basierter Informationen in neue Funktionen Angewandte Chemie. 125: 6956-6980. DOI: 10.1002/Ange.201208460 |
0.581 |
|
| 2012 |
Sadhu KK, Eierhoff T, Römer W, Winssinger N. Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo. Journal of the American Chemical Society. 134: 20013-6. PMID 23186060 DOI: 10.1021/ja310171s |
0.674 |
|
| 2012 |
Chouikhi D, Ciobanu M, Zambaldo C, Duplan V, Barluenga S, Winssinger N. Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12698-704. PMID 22915361 DOI: 10.1002/Chem.201201337 |
0.805 |
|
| 2012 |
Karthikeyan G, Zambaldo C, Barluenga S, Zoete V, Karplus M, Winssinger N. Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8978-86. PMID 22696415 DOI: 10.1002/Chem.201200546 |
0.784 |
|
| 2012 |
Valot G, Garcia J, Duplan V, Serba C, Barluenga S, Winssinger N. Diversity-oriented synthesis of diverse polycyclic scaffolds inspired by the logic of sesquiterpene lactones biosynthesis. Angewandte Chemie (International Ed. in English). 51: 5391-4. PMID 22517777 DOI: 10.1002/Anie.201201157 |
0.787 |
|
| 2012 |
Daguer JP, Ciobanu M, Barluenga S, Winssinger N. Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries. Organic & Biomolecular Chemistry. 10: 1502-5. PMID 22237952 DOI: 10.1039/C2Ob06880J |
0.795 |
|
| 2012 |
Röthlingshöfer M, Gorska K, Winssinger N. Nucleic acid templated uncaging of fluorophores using Ru-catalyzed photoreduction with visible light. Organic Letters. 14: 482-5. PMID 22206275 DOI: 10.1021/Ol203029T |
0.8 |
|
| 2012 |
Hamidi A, von Bulow V, Hamidi R, Winssinger N, Barluenga S, Heldin CH, Landström M. Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli. The Journal of Biological Chemistry. 287: 123-33. PMID 22069318 DOI: 10.1074/Jbc.M111.285122 |
0.691 |
|
| 2012 |
Garcia J, Barluenga S, Gorska K, Sasse F, Winssinger N. Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions. Bioorganic & Medicinal Chemistry. 20: 672-80. PMID 22037048 DOI: 10.1016/J.Bmc.2011.09.064 |
0.796 |
|
| 2011 |
Röthlingshöfer M, Gorska K, Winssinger N. Nucleic acid-templated energy transfer leading to a photorelease reaction and its application to a system displaying a nonlinear response. Journal of the American Chemical Society. 133: 18110-3. PMID 22004511 DOI: 10.1021/Ja2086504 |
0.782 |
|
| 2011 |
Ciobanu M, Huang KT, Daguer JP, Barluenga S, Chaloin O, Schaeffer E, Mueller CG, Mitchell DA, Winssinger N. Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells. Chemical Communications (Cambridge, England). 47: 9321-3. PMID 21785785 DOI: 10.1039/C1Cc13213J |
0.795 |
|
| 2011 |
Gorska K, Manicardi A, Barluenga S, Winssinger N. DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker. Chemical Communications (Cambridge, England). 47: 4364-6. PMID 21369617 DOI: 10.1039/C1Cc10222B |
0.806 |
|
| 2011 |
Leproult E, Barluenga S, Moras D, Wurtz JM, Winssinger N. Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. Journal of Medicinal Chemistry. 54: 1347-55. PMID 21322567 DOI: 10.1021/Jm101396Q |
0.746 |
|
| 2011 |
Huang KT, Gorska K, Alvarez S, Barluenga S, Winssinger N. Combinatorial self-assembly of glycan fragments into microarrays. Chembiochem : a European Journal of Chemical Biology. 12: 56-60. PMID 21154493 DOI: 10.1002/Cbic.201000567 |
0.803 |
|
| 2011 |
Gorska K, Keklikoglou I, Tschulena U, Winssinger N. Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction Chemical Science. 2: 1969-1975. DOI: 10.1039/C1Sc00216C |
0.537 |
|
| 2011 |
Daguer JP, Ciobanu M, Alvarez S, Barluenga S, Winssinger N. DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles Chemical Science. 2: 625-632. DOI: 10.1039/C0Sc00574F |
0.749 |
|
| 2010 |
Grad I, Cederroth CR, Walicki J, Grey C, Barluenga S, Winssinger N, De Massy B, Nef S, Picard D. The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse. Plos One. 5: e15770. PMID 21209834 DOI: 10.1371/Journal.Pone.0015770 |
0.716 |
|
| 2010 |
Gorska K, Beyrath J, Fournel S, Guichard G, Winssinger N. Ligand dimerization programmed by hybridization to study multimeric ligand-receptor interactions. Chemical Communications (Cambridge, England). 46: 7742-4. PMID 20852806 DOI: 10.1039/C0Cc02852E |
0.571 |
|
| 2010 |
Zhu H, Woolfenden S, Bronson RT, Jaffer ZM, Barluenga S, Winssinger N, Rubenstein AE, Chen R, Charest A. The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme. Molecular Cancer Therapeutics. 9: 2618-26. PMID 20643786 DOI: 10.1158/1535-7163.Mct-10-0248 |
0.732 |
|
| 2010 |
Barluenga S, Jogireddy R, Koripelly GK, Winssinger N. In vivo efficacy of natural product-inspired irreversible kinase inhibitors. Chembiochem : a European Journal of Chemical Biology. 11: 1692-9. PMID 20623569 DOI: 10.1002/Cbic.201000205 |
0.795 |
|
| 2010 |
Garcia J, Barluenga S, Beebe K, Neckers L, Winssinger N. Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9767-71. PMID 20572190 DOI: 10.1002/Chem.201001080 |
0.742 |
|
| 2010 |
Chouikhi D, Barluenga S, Winssinger N. Clickable peptide nucleic acids (cPNA) with tunable affinity. Chemical Communications (Cambridge, England). 46: 5476-8. PMID 20571635 DOI: 10.1039/C0Cc01081B |
0.809 |
|
| 2010 |
Jogireddy R, Barluenga S, Winssinger N. Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL. Chemmedchem. 5: 670-3. PMID 20209566 DOI: 10.1002/Cmdc.201000047 |
0.808 |
|
| 2010 |
Gassman NR, Nelli JP, Dutta S, Kuhn A, Bonin K, Pianowski Z, Winssinger N, Guthold M, Macosko JC. Selection of bead-displayed, PNA-encoded chemicals. Journal of Molecular Recognition : Jmr. 23: 414-22. PMID 19957300 DOI: 10.1002/Jmr.1007 |
0.744 |
|
| 2010 |
Broggini-Tenzer A, Hollenstein A, Pianowski Z, Wampfler A, Furmanova P, Winssinger N, Pruschy M. Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation. Proteomics. 10: 304-14. PMID 19957288 DOI: 10.1002/Pmic.200900162 |
0.705 |
|
| 2010 |
Jogireddy R, Barluenga S, Winssinger N. Cover Picture: Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL (ChemMedChem 5/2010) Chemmedchem. 5: 633-633. DOI: 10.1002/Cmdc.201090015 |
0.793 |
|
| 2010 |
Nicolaou KC, Pfefferkorn J, Xu J, Winssinger N, Ohshima T, Kim S, Hosokawa S, Vourloumis D, van Delft F, Li T. ChemInform Abstract: Total Synthesis and Chemical Biology of the Sarcodictyins Cheminform. 31: no-no. DOI: 10.1002/chin.200011255 |
0.396 |
|
| 2010 |
Nicolaou KC, Ohshima T, Murphy F, Barluenga S, Xu J, Winssinger N. ChemInform Abstract: Synthesis of the Macrocyclic Core of Sanglifehrin A. Cheminform. 30: no-no. DOI: 10.1002/chin.199934254 |
0.744 |
|
| 2010 |
Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. ChemInform Abstract: Total Synthesis of Vancomycin. Cheminform. 30: no-no. DOI: 10.1002/chin.199918228 |
0.64 |
|
| 2010 |
NICOLAOU KC, PASTOR J, BARLUENGA S, WINSSINGER N. ChemInform Abstract: Polymer-Supported Selenium Reagents for Organic Synthesis. Cheminform. 30: no-no. DOI: 10.1002/chin.199902057 |
0.721 |
|
| 2010 |
NICOLAOU KC, WINSSINGER N, PASTOR J, NINKOVIC S, SARABLA F, HE Y, VOURLOUMIS D, YANG Z, LI T, GIANNAKAKOU P, HAMEL E. ChemInform Abstract: Synthesis of Epothilones A and B in Solid and Solution Phase. Cheminform. 28: no-no. DOI: 10.1002/chin.199737271 |
0.307 |
|
| 2010 |
Barluenga S, Dakas PY, Jogireddy R, Valot G, Winssinger N. Metathesis Reactions in Solid-Phase Organic Synthesis Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts. 349-372. DOI: 10.1002/9783527629626.ch13 |
0.781 |
|
| 2009 |
Winssinger N, Fontaine JG, Barluenga S. Hsp90 inhibition with resorcyclic acid lactones (RALs). Current Topics in Medicinal Chemistry. 9: 1419-35. PMID 19860733 DOI: 10.2174/156802609789895665 |
0.768 |
|
| 2009 |
Barluenga S, Fontaine JG, Wang C, Aouadi K, Chen R, Beebe K, Neckers L, Winssinger N. Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem : a European Journal of Chemical Biology. 10: 2753-9. PMID 19856365 DOI: 10.1002/Cbic.200900494 |
0.791 |
|
| 2009 |
Jogireddy R, Dakas PY, Valot G, Barluenga S, Winssinger N. Synthesis of a resorcylic acid lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11498-506. PMID 19821461 DOI: 10.1002/Chem.200901375 |
0.805 |
|
| 2009 |
Dakas PY, Jogireddy R, Valot G, Barluenga S, Winssinger N. Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11490-7. PMID 19821460 DOI: 10.1002/Chem.200901373 |
0.791 |
|
| 2009 |
Gorska K, Huang KT, Chaloin O, Winssinger N. DNA-templated homo- and heterodimerization of peptide nucleic acid encoded oligosaccharides that mimick the carbohydrate epitope of HIV. Angewandte Chemie (International Ed. in English). 48: 7695-700. PMID 19774579 DOI: 10.1002/Anie.200903328 |
0.678 |
|
| 2009 |
Debaene F, Winssinger N. Self-assembly of PNA-encoded peptides into microarrays. Methods in Molecular Biology (Clifton, N.J.). 570: 299-307. PMID 19649601 DOI: 10.1007/978-1-60327-394-7_15 |
0.736 |
|
| 2009 |
Spichty M, Taly A, Hagn F, Kessler H, Barluenga S, Winssinger N, Karplus M. The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts. Biophysical Chemistry. 143: 111-23. PMID 19482409 DOI: 10.1016/J.Bpc.2009.04.003 |
0.732 |
|
| 2009 |
Wang C, Barluenga S, Koripelly GK, Fontaine JG, Chen R, Yu JC, Shen X, Chabala JC, Heck JV, Rubenstein A, Winssinger N. Synthesis of pochoxime prodrugs as potent HSP90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 3836-40. PMID 19410458 DOI: 10.1016/J.Bmcl.2009.04.030 |
0.794 |
|
| 2009 |
Pianowski Z, Gorska K, Oswald L, Merten CA, Winssinger N. Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes. Journal of the American Chemical Society. 131: 6492-7. PMID 19378999 DOI: 10.1021/Ja809656K |
0.785 |
|
| 2009 |
Dakas P, Jogireddy R, Valot G, Barluenga S, Winssinger N. Cover Picture: Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin / Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases (Chem. Chemistry - a European Journal. 15: 11409-11409. DOI: 10.1002/Chem.200990168 |
0.807 |
|
| 2009 |
Winssinger N, Barluenga S, Dakas PY. High-Throughput Synthesis of Natural Products The Power of Functional Resins in Organic Synthesis. 613-640. DOI: 10.1002/9783527626175.ch21 |
0.788 |
|
| 2008 |
García-Cuadrado D, Barluenga S, Winssinger N. Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents. Chemical Communications (Cambridge, England). 4619-21. PMID 18815703 DOI: 10.1039/B807869F |
0.798 |
|
| 2008 |
Pianowski ZL, Winssinger N. Nucleic acid encoding to program self-assembly in chemical biology. Chemical Society Reviews. 37: 1330-6. PMID 18568159 DOI: 10.1039/b706610b |
0.722 |
|
| 2008 |
Barluenga S, Wang C, Fontaine JG, Aouadi K, Beebe K, Tsutsumi S, Neckers L, Winssinger N. Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor. Angewandte Chemie (International Ed. in English). 47: 4432-5. PMID 18435518 DOI: 10.1002/Anie.200800233 |
0.802 |
|
| 2008 |
Dakas P-, Barluenga S, Totzke F, Zirrgiebel U, Winssinger N. Synthesis of Radicicol A Synfacts. 2008: 116-116. DOI: 10.1055/S-2007-992505 |
0.351 |
|
| 2008 |
Barluenga S, Dakas PY, Boulifa M, Moulin E, Winssinger N. Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential Comptes Rendus Chimie. 11: 1306-1317. DOI: 10.1016/J.Crci.2008.01.020 |
0.801 |
|
| 2008 |
Pothukanuri S, Pianowski Z, Winssinger N. Expanding the scope and orthogonality of PNA synthesis European Journal of Organic Chemistry. 3141-3148. DOI: 10.1002/Ejoc.200800141 |
0.808 |
|
| 2007 |
Pianowski ZL, Winssinger N. Fluorescence-based detection of single nucleotide permutation in DNA via catalytically templated reaction. Chemical Communications (Cambridge, England). 3820-2. PMID 18217658 DOI: 10.1039/B709611A |
0.71 |
|
| 2007 |
Dakas PY, Barluenga S, Totzke F, Zirrgiebel U, Winssinger N. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angewandte Chemie (International Ed. in English). 46: 6899-902. PMID 17676571 DOI: 10.1002/Anie.200702406 |
0.807 |
|
| 2007 |
Pothukanuri S, Winssinger N. A highly efficient azide-based protecting group for amines and alcohols. Organic Letters. 9: 2223-5. PMID 17480087 DOI: 10.1021/ol0707160 |
0.781 |
|
| 2007 |
Winssinger N, Barluenga S. Chemistry and biology of resorcylic acid lactones. Chemical Communications (Cambridge, England). 22-36. PMID 17279252 DOI: 10.1039/B610344H |
0.744 |
|
| 2007 |
Debaene F, Da Silva JA, Pianowski Z, Duran FJ, Winssinger N. Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metallo-proteases as well as tyrosine phosphatases Tetrahedron. 63: 6577-6586. DOI: 10.1016/J.Tet.2007.03.033 |
0.816 |
|
| 2007 |
Winssinger N, Pianowski Z, Debaene F. Probing biology with Small Molecule Microarrays (SMM) Topics in Current Chemistry. 278: 311-342. DOI: 10.1007/128_2007_109 |
0.781 |
|
| 2007 |
Huang KT, Winssinger N. IPy2BF4-mediated glycosylation and glycosyl fluoride formation European Journal of Organic Chemistry. 1887-1890. DOI: 10.1002/Ejoc.200700038 |
0.517 |
|
| 2007 |
Winssinger N, Pianowski Z, Barluenga S. Chemical Technologies: Probing Biology with Small Molecules Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine. 109-144. DOI: 10.1002/9780470199138.ch5 |
0.777 |
|
| 2006 |
Urbina HD, Debaene F, Jost B, Bole-Feysot C, Mason DE, Kuzmic P, Harris JL, Winssinger N. Self-assembled small-molecule microarrays for protease screening and profiling. Chembiochem : a European Journal of Chemical Biology. 7: 1790-7. PMID 17009273 DOI: 10.1002/Cbic.200600242 |
0.775 |
|
| 2006 |
Moulin E, Barluenga S, Totzke F, Winssinger N. Diversity-oriented synthesis of pochonins and biological evaluation against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 8819-34. PMID 16953513 DOI: 10.1002/Chem.200600553 |
0.816 |
|
| 2006 |
Barluenga S, Dakas PY, Ferandin Y, Meijer L, Winssinger N. Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold. Angewandte Chemie (International Ed. in English). 45: 3951-4. PMID 16683294 DOI: 10.1002/Anie.200600593 |
0.804 |
|
| 2006 |
Winssinger N, Barluenga S, Dakas P, Ferandin Y, Meijer L. Polymer-Supported Synthesis of Aigialomycin D Synfacts. 2006: 0961-0961. DOI: 10.1055/S-2006-949249 |
0.769 |
|
| 2006 |
Barluenga S, Moulin E, Lopez P, Winssinger N. Solution- and Solid-Phase Synthesis of Radicicol (Monorden) (I) and Pochonin C (II). Cheminform. 37. DOI: 10.1002/chin.200615210 |
0.768 |
|
| 2005 |
Moulin E, Barluenga S, Winssinger N. Concise synthesis of pochonin A, an HSP90 inhibitor. Organic Letters. 7: 5637-9. PMID 16321010 DOI: 10.1021/Ol052263+ |
0.813 |
|
| 2005 |
Winssinger N, Harris JL. Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries. Expert Review of Proteomics. 2: 937-47. PMID 16307522 DOI: 10.1586/14789450.2.6.937 |
0.514 |
|
| 2005 |
Harris JL, Winssinger N. PNA encoding (PNA=peptide nucleic acid): from solution-based libraries to organized microarrays. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 6792-801. PMID 16038006 DOI: 10.1002/Chem.200500305 |
0.537 |
|
| 2005 |
Barluenga S, Moulin E, Lopez P, Winssinger N. Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 4935-52. PMID 15940738 DOI: 10.1002/Chem.200500160 |
0.798 |
|
| 2005 |
Moulin E, Zoete V, Barluenga S, Karplus M, Winssinger N. Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues. Journal of the American Chemical Society. 127: 6999-7004. PMID 15884943 DOI: 10.1021/Ja043101W |
0.806 |
|
| 2004 |
Spence MM, Ruiz EJ, Rubin SM, Lowery TJ, Winssinger N, Schultz PG, Wemmer DE, Pines A. Development of a functionalized xenon biosensor. Journal of the American Chemical Society. 126: 15287-94. PMID 15548026 DOI: 10.1021/Ja0483037 |
0.51 |
|
| 2004 |
Harris J, Mason DE, Li J, Burdick KW, Backes BJ, Chen T, Shipway A, Van Heeke G, Gough L, Ghaemmaghami A, Shakib F, Debaene F, Winssinger N. Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays. Chemistry & Biology. 11: 1361-72. PMID 15489163 DOI: 10.1016/J.Chembiol.2004.08.008 |
0.763 |
|
| 2004 |
Winssinger N, Damoiseaux R, Tully DC, Geierstanger BH, Burdick K, Harris JL. PNA-encoded protease substrate microarrays. Chemistry & Biology. 11: 1351-60. PMID 15489162 DOI: 10.1016/J.Chembiol.2004.07.015 |
0.477 |
|
| 2004 |
Barluenga S, Lopez P, Moulin E, Winssinger N. Modular asymmetric synthesis of pochonin C. Angewandte Chemie (International Ed. in English). 43: 3467-70. PMID 15221842 DOI: 10.1002/Anie.200454108 |
0.785 |
|
| 2004 |
Debaene F, Mejias L, Harris JL, Winssinger N. Synthesis of a PNA-encoded cysteine protease inhibitor library Tetrahedron. 60: 8677-8690. DOI: 10.1016/J.Tet.2004.05.107 |
0.788 |
|
| 2003 |
Lowery TJ, Rubin SM, Ruiz EJ, Spence MM, Winssinger N, Schultz PG, Pines A, Wemmer DE. Applications of laser-polarized 129Xe to biomolecular assays. Magnetic Resonance Imaging. 21: 1235-9. PMID 14725931 DOI: 10.1016/J.Mri.2003.08.025 |
0.541 |
|
| 2003 |
Debaene F, Winssinger N. Azidopeptide nucleic acid. An alternative strategy for solid-phase peptide nucleic acid (PNA) synthesis. Organic Letters. 5: 4445-7. PMID 14602021 DOI: 10.1021/Ol0358408 |
0.732 |
|
| 2003 |
Nicolaou KC, Roecker AJ, Hughes R, van Summeren R, Pfefferkorn JA, Winssinger N. Novel strategies for the solid phase synthesis of substituted indolines and indoles. Bioorganic & Medicinal Chemistry. 11: 465-76. PMID 12517442 DOI: 10.1016/S0968-0896(02)00386-3 |
0.797 |
|
| 2002 |
Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proceedings of the National Academy of Sciences of the United States of America. 99: 11139-44. PMID 12167675 DOI: 10.1073/Pnas.172286899 |
0.647 |
|
| 2001 |
Winssinger N, Harris JL, Backes BJ, Schultz PG. From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling. Angewandte Chemie (International Ed. in English). 40: 3152-3155. PMID 29712061 DOI: 10.1002/1521-3773(20010903)40:17<3152::Aid-Anie3152>3.0.Co;2-P |
0.664 |
|
| 2001 |
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Labischinski H, Endermann R. Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 3824-43. PMID 11575783 DOI: 10.1002/1521-3765(20010903)7:17<3824::Aid-Chem3824>3.0.Co;2-1 |
0.635 |
|
| 2001 |
Nicolaou KC, Cho SY, Hughes R, Winssinger N, Smethurst C, Labischinski H, Endermann R. Solid- and solution-phase synthesis of vancomycin and vancomycin analogues with activity against vancomycin-resistant bacteria. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 3798-823. PMID 11575782 DOI: 10.1002/1521-3765(20010903)7:17<3798::Aid-Chem3798>3.0.Co;2-6 |
0.584 |
|
| 2001 |
Winssinger N, Harris JL, Backes BJ, Schultz PG. From split-pool libraries to spatially addressable microarrays and its application to functional proteomic profiling Angewandte Chemie - International Edition. 40: 3152-3155. DOI: 10.1002/1521-3773(20010903)40:17<3152::AID-ANIE3152>3.0.CO;2-P |
0.609 |
|
| 2001 |
Winssinger N, Harris JL, Backes BJ, Schultz PG. Cover Picture Angewandte Chemie International Edition. 40: 3083-3083. DOI: 10.1002/1521-3773(20010903)40:17<3083::AID-ANIE3083>3.0.CO;2-J |
0.586 |
|
| 2001 |
Winssinger N, Harris JL, Backes BJ, Schultz PG. Von Split-Pool-Molekülbibliotheken zu räumlich adressierbaren Mikro-Arrays und deren Einsatz in der funktionellen Proteomik Angewandte Chemie. 113: 3254-3258. DOI: 10.1002/1521-3757(20010903)113:17<3254::Aid-Ange3254>3.0.Co;2-9 |
0.627 |
|
| 2001 |
Nicolaou KC, Safina BS, Winssinger N. A new photolabile linker for the photoactivation of carboxyl groups Synlett. 900-903. |
0.656 |
|
| 2000 |
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Smethurst C, Labischinski H, Endermann R. Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria. Angewandte Chemie (International Ed. in English). 39: 3823-3828. PMID 29711708 DOI: 10.1002/1521-3773(20001103)39:21<3823::Aid-Anie3823>3.0.Co;2-3 |
0.58 |
|
| 2000 |
Nicolaou KC, Hepworth D, King NP, Finlay MR, Scarpelli R, Pereira MM, Bollbuck B, Bigot A, Werschkun B, Winssinger N. Total synthesis of 16-desmethylepothilone B, epothilone B10, epothilone F, and related side chain modified epothilone B analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2783-800. PMID 10985727 DOI: 10.1002/1521-3765(20000804)6:15<2783::Aid-Chem2783>3.0.Co;2-B |
0.322 |
|
| 2000 |
Nicolaou KC, Winssinger N, Hughes R, Smethurst C, Cho SY. New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, a fellowship from the George Hewitt Foundation (N. W.), and grants from Schering Plough, Pfizer, Glaxo, Merck, Hoffmann-La Roche, DuPont, and Abbott Laboratories. Angewandte Chemie (International Ed. in English). 39: 1084-1088. PMID 10760929 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1084::Aid-Anie1084>3.0.Co;2-O |
0.581 |
|
| 2000 |
Nicolaou KC, Vourloumis D, Winssinger N, Baran PS. The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century. Angewandte Chemie (International Ed. in English). 39: 44-122. PMID 10649349 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<44::Aid-Anie44>3.0.Co;2-L |
0.54 |
|
| 2000 |
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Smethurst C, Labischinski H, Endermann R. Target-accelerated combinatorial synthesis and discovery of highly potent antibiotics effective against vancomycin-resistant bacteria Angewandte Chemie - International Edition. 39: 3823-3828. DOI: 10.1002/1521-3773(20001103)39:21<3823::AID-ANIE3823>3.0.CO;2-3 |
0.347 |
|
| 2000 |
Nicolaou KC, Vourloumis D, Winssinger N, Baran PS. Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts Angewandte Chemie. 112: 46-126. DOI: 10.1002/(Sici)1521-3757(20000103)112:1<46::Aid-Ange46>3.0.Co;2-P |
0.519 |
|
| 1999 |
Nicolaou KC, Pfefferkorn J, Xu J, Winssinger N, Ohshima T, Kim S, Hosokawa S, Vourloumis D, van Delft F, Li T. Total synthesis and chemical biology of the sarcodictyins. Chemical & Pharmaceutical Bulletin. 47: 1199-213. PMID 10517002 DOI: 10.1248/Cpb.47.1199 |
0.696 |
|
| 1999 |
Nicolaou KC, Boddy CN, Bräse S, Winssinger N. Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics. Angewandte Chemie (International Ed. in English). 38: 2096-2152. PMID 10425471 DOI: 10.1002/(Sici)1521-3773(19990802)38:15<2096::Aid-Anie2096>3.0.Co;2-F |
0.655 |
|
| 1999 |
Nicolaou KC, Winssinger N, Vourloumis D, Ohshima T, Kim S, Pfefferkorn J, Xu JY, Li T, Hosokawa S. Total synthesis of sarcodictyins A and B: Solid- and solution-phase synthesis and biological evaluation of combinatorial sarcodictyin libraries Chemtracts. 12: 1006-1012. DOI: 10.1021/Ja981062G |
0.662 |
|
| 1999 |
Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. Total Synthesis of Vancomycin Angewandte Chemie International Edition. 38: 240-244. DOI: 10.1002/(Sici)1521-3773(19990115)38:1/2<240::Aid-Anie240>3.0.Co;2-5 |
0.725 |
|
| 1999 |
Nicolaou KC, Mitchell HJ, Jain NF, Bando T, Hughes R, Winssinger N, Natarajan S, Koumbis AE. Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis Chemistry - a European Journal. 5: 2648-2667. DOI: 10.1002/(Sici)1521-3765(19990903)5:9<2648::Aid-Chem2648>3.0.Co;2-Q |
0.761 |
|
| 1999 |
Nicolaou KC, Boddy CNC, Bräse S, Winssinger N. Chemie, Biologie und medizinische Anwendungen der Glycopeptid-Antibiotika Angewandte Chemie. 111: 2230-2287. DOI: 10.1002/(Sici)1521-3757(19990802)111:15<2230::Aid-Ange2230>3.0.Co;2-V |
0.482 |
|
| 1999 |
Nicolaou KC, Mitchell HJ, Jain NF, Winssinger N, Hughes R, Bando T. Totalsynthese von Vancomycin Angewandte Chemie. 111: 253-255. DOI: 10.1002/(Sici)1521-3757(19990115)111:1/2<253::Aid-Ange253>3.0.Co;2-V |
0.698 |
|
| 1999 |
Nicolaou KC, Ohshima T, Murphy F, Barluenga S, Xu J, Winssinger N. Synthesis of the macrocyclic core of sanglifehrin A Chemical Communications. 809-810. |
0.72 |
|
| 1999 |
Nicolaou KC, Mitchell HJ, Jain NF, Bando T, Hughes R, Winssinger N, Natarajan S, Koumbis AE. Total synthesis of vancomycin - Part 4: Attachment of the sugar moieties and completion of the synthesis Chemistry - a European Journal. 5: 2648-2667. |
0.607 |
|
| 1998 |
Nicolaou KC, Winssinger N, Pastor J, Murphy F. Solid-Phase Synthesis of Macrocyclic Systems by a Cyclorelease Strategy: Application of the Stille Coupling to a Synthesis of (S)-Zearalenone. Angewandte Chemie (International Ed. in English). 37: 2534-2537. PMID 29711345 DOI: 10.1002/(Sici)1521-3773(19981002)37:18<2534::Aid-Anie2534>3.0.Co;2-F |
0.351 |
|
| 1998 |
Nicolaou KC, Watanabe N, Li J, Pastor J, Winssinger N. Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide. Angewandte Chemie (International Ed. in English). 37: 1559-1561. PMID 29710918 DOI: 10.1002/(Sici)1521-3773(19980619)37:11<1559::Aid-Anie1559>3.0.Co;2-E |
0.541 |
|
| 1998 |
Nicolaou KC, Winssinger N, Vourloumis D, Ohshima T, Kim S, Pfefferkorn J, Xu JY, Li T. Solid and solution phase synthesis and biological evaluation of combinatorial sarcodictyin libraries Journal of the American Chemical Society. 120: 10814-10826. DOI: 10.1021/Ja9823870 |
0.663 |
|
| 1998 |
Nicolaou KC, Pastor J, Winssinger N, Murphy F. Solid phase synthesis of macrocycles by an intramolecular ketophosphonate reaction. Synthesis of a (dl)-muscone library [11] Journal of the American Chemical Society. 120: 5132-5133. DOI: 10.1021/Ja980675Q |
0.383 |
|
| 1998 |
Nicolaou KC, Sorensen EJ, Winssinger N. The Art and Science of Organic and Natural Products Synthesis Journal of Chemical Education. 75: 1225-1258. DOI: 10.1021/Ed075P1225 |
0.587 |
|
| 1998 |
Nicolaou KC, Winssinger N, Pastor J, Murphy F. Solid-phase synthesis of macrocyclic systems by a cyclorelease strategy: Application of the stille coupling to a synthesis of (S)-zearalenone Angewandte Chemie - International Edition. 37: 2534-2537. DOI: 10.1002/(SICI)1521-3773(19981002)37:18<2534::AID-ANIE2534>3.0.CO;2-F |
0.363 |
|
| 1998 |
Nicolaou KC, Watanabe N, Li J, Pastor J, Winssinger N. Solid-phase synthesis of oligosaccharides: Construction of a dodecasaccharide Angewandte Chemie - International Edition. 37: 1559-1561. DOI: 10.1002/(SICI)1521-3773(19980619)37:11<1559::AID-ANIE1559>3.0.CO;2-E |
0.333 |
|
| 1998 |
Nicolaou KC, Winssinger N, Pastor J, Murphy F. Festphasensynthese von Makrocyclen mit der Strategie der Abspaltung unter Cyclisierung: Anwendung der Stille-Kupplung bei der Synthese von (S)-Zearalenon Angewandte Chemie. 110: 2677-2680. DOI: 10.1002/(Sici)1521-3757(19980918)110:18<2677::Aid-Ange2677>3.0.Co;2-C |
0.384 |
|
| 1998 |
Nicolaou K, Watanabe N, Li J, Pastor J, Winssinger N. Einfache Festphasensynthese von Oligosacchariden – Herstellung eines Dodecasaccharids Angewandte Chemie. 110: 1636-1638. DOI: 10.1002/(Sici)1521-3757(19980605)110:11<1636::Aid-Ange1636>3.0.Co;2-H |
0.528 |
|
| 1998 |
Nicolaou KC, Sorensen EJ, Winssinger N. The art and science of organic and natural products synthesis Journal of Chemical Education. 75: 1226-1258. |
0.468 |
|
| 1998 |
Nicolaou KC, Pastor J, Barluenga S, Winssinger N. Polymer-supported selenium reagents for organic synthesis Chemical Communications. 1947-1948. |
0.692 |
|
| 1997 |
Nicolaou KC, Winssinger N, Pastor J, Ninkovic S, Sarabia F, He Y, Vourloumis D, Yang Z, Li T, Giannakakou P, Hamel E. Synthesis of epothilones A and B in solid and solution phase. Nature. 387: 268-72. PMID 9153390 DOI: 10.1038/387268A0 |
0.591 |
|
| 1997 |
Nicolaou KC, Winssinger N, Pastor J, Ninkovic S, Sarabia F, He Y, Vourloumis D, Yang Z, Li T, Giannakakou P, Hamel E. Correction: Synthesis of epothilones A and B in solid and solution phase Nature. 390: 100-100. DOI: 10.1038/36382 |
0.596 |
|
| 1997 |
Nicolaou KC, Winssinger N, Pastor J, DeRoose F. A general and highly efficient solid phase synthesis of oligosacharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE) Journal of the American Chemical Society. 119: 449-450. DOI: 10.1021/Ja963482G |
0.382 |
|
| 1997 |
Nicolaou KC, Vourloumis D, Li T, Pastor J, Winssinger N, He Y, Ninkovic S, Sarabia F, Vallberg H, Roschanger F, King NP, Finlay MRV, Giannakakou P, Verdier-Pinard P, Hamel E. Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin-Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen Angewandte Chemie. 109: 2181-2187. DOI: 10.1002/Ange.19971091917 |
0.542 |
|
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