Elena Pasquale - Publications

Affiliations: 
The Burnham Institute, Taplow, England, United Kingdom 
Area:
Eph Receptors

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Amegandjin CA, Jammow W, Laforest S, Riad M, Baharnoori M, Badeaux F, DesGroseillers L, Murai KK, Pasquale EB, Drolet G, Doucet G. Regional expression and ultrastructural localization of EphA7 in the hippocampus and cerebellum of adult rat. The Journal of Comparative Neurology. PMID 26780036 DOI: 10.1002/cne.23962  0.36
2015 Riedl SJ, Pasquale EB. Targeting the Eph System with Peptides and Peptide Conjugates. Current Drug Targets. 16: 1031-47. PMID 26212263  0.84
2015 Forse GJ, Uson ML, Nasertorabi F, Kolatkar A, Lamberto I, Pasquale EB, Kuhn P. Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5. Plos One. 10: e0127081. PMID 25993310 DOI: 10.1371/journal.pone.0127081  0.84
2015 Bhatia S, Baig NA, Timofeeva O, Pasquale EB, Hirsch K, MacDonald TJ, Dritschilo A, Lee YC, Henkemeyer M, Rood B, Jung M, Wang XJ, Kool M, Rodriguez O, Albanese C, et al. Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization. Oncotarget. 6: 8929-46. PMID 25879388  0.84
2015 Paraiso KH, Das Thakur M, Fang B, Koomen JM, Fedorenko IV, John JK, Tsao H, Flaherty KT, Sondak VK, Messina JL, Pasquale EB, Villagra A, Rao UN, Kirkwood JM, Meier F, et al. Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype. Cancer Discovery. 5: 264-73. PMID 25542447 DOI: 10.1158/2159-8290.CD-14-0293  0.84
2015 Barquilla A, Pasquale EB. Eph receptors and ephrins: therapeutic opportunities. Annual Review of Pharmacology and Toxicology. 55: 465-87. PMID 25292427 DOI: 10.1146/annurev-pharmtox-011112-140226  0.84
2014 Lamberto I, Lechtenberg BC, Olson EJ, Mace PD, Dawson PE, Riedl SJ, Pasquale EB. Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor. Acs Chemical Biology. 9: 2787-95. PMID 25268696 DOI: 10.1021/cb500677x  0.84
2014 Barile E, Wang S, Das SK, Noberini R, Dahl R, Stebbins JL, Pasquale EB, Fisher PB, Pellecchia M. Design, synthesis and bioevaluation of an EphA2 receptor-based targeted delivery system. Chemmedchem. 9: 1403-12. PMID 24677792 DOI: 10.1002/cmdc.201400067  0.84
2014 Vargas LM, Leal N, Estrada LD, González A, Serrano F, Araya K, Gysling K, Inestrosa NC, Pasquale EB, Alvarez AR. EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers. Plos One. 9: e92309. PMID 24658113 DOI: 10.1371/journal.pone.0092309  0.84
2014 Hassan-Mohamed I, Giorgio C, Incerti M, Russo S, Pala D, Pasquale EB, Zanotti I, Vicini P, Barocelli E, Rivara S, Mor M, Lodola A, Tognolini M. UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations. British Journal of Pharmacology. 171: 5195-208. PMID 24597515 DOI: 10.1111/bph.12669  0.84
2014 Wallez Y, Riedl SJ, Pasquale EB. Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance. The Journal of Biological Chemistry. 289: 10431-44. PMID 24584939 DOI: 10.1074/jbc.M113.541839  0.84
2013 Falivelli G, Lisabeth EM, Rubio de la Torre E, Perez-Tenorio G, Tosato G, Salvucci O, Pasquale EB. Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands. Plos One. 8: e81445. PMID 24348920 DOI: 10.1371/journal.pone.0081445  0.84
2013 Duggineni S, Mitra S, Lamberto I, Han X, Xu Y, An J, Pasquale EB, Huang Z. Design and Synthesis of Potent Bivalent Peptide Agonists Targeting the EphA2 Receptor. Acs Medicinal Chemistry Letters. 4. PMID 24167659 DOI: 10.1021/ml3004523  0.84
2013 Huan X, Shi J, Lim L, Mitra S, Zhu W, Qin H, Pasquale EB, Song J. Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulations. Plos One. 8: e74040. PMID 24086308 DOI: 10.1371/journal.pone.0074040  0.84
2013 Lisabeth EM, Falivelli G, Pasquale EB. Eph receptor signaling and ephrins. Cold Spring Harbor Perspectives in Biology. 5. PMID 24003208 DOI: 10.1101/cshperspect.a009159  0.84
2013 Jellinghaus S, Poitz DM, Ende G, Augstein A, Weinert S, Stütz B, Braun-Dullaeus RC, Pasquale EB, Strasser RH. Ephrin-A1/EphA4-mediated adhesion of monocytes to endothelial cells. Biochimica Et Biophysica Acta. 1833: 2201-11. PMID 23707953 DOI: 10.1016/j.bbamcr.2013.05.017  0.84
2013 Mace PD, Wallez Y, Egger MF, Dobaczewska MK, Robinson H, Pasquale EB, Riedl SJ. Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nature Communications. 4: 1681. PMID 23575685 DOI: 10.1038/ncomms2687  0.84
2013 Incerti M, Tognolini M, Russo S, Pala D, Giorgio C, Hassan-Mohamed I, Noberini R, Pasquale EB, Vicini P, Piersanti S, Rivara S, Barocelli E, Mor M, Lodola A. Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. Journal of Medicinal Chemistry. 56: 2936-47. PMID 23489211 DOI: 10.1021/jm301890k  0.84
2013 Wu B, Zhang Z, Noberini R, Barile E, Giulianotti M, Pinilla C, Houghten RA, Pasquale EB, Pellecchia M. HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery. Chemistry & Biology. 20: 19-33. PMID 23352136 DOI: 10.1016/j.chembiol.2012.10.015  0.84
2013 Duggineni S, Mitra S, Noberini R, Han X, Lin N, Xu Y, Tian W, An J, Pasquale EB, Huang Z. Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4. Biochemical Pharmacology. 85: 507-13. PMID 23253822 DOI: 10.1016/j.bcp.2012.12.005  0.84
2013 Wang S, Noberini R, Stebbins JL, Das S, Zhang Z, Wu B, Mitra S, Billet S, Fernandez A, Bhowmick NA, Kitada S, Pasquale EB, Fisher PB, Pellecchia M. Targeted delivery of paclitaxel to EphA2-expressing cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 128-37. PMID 23155185 DOI: 10.1158/1078-0432.CCR-12-2654  0.84
2012 Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, ... ... Pasquale EB, et al. The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell. 22: 765-80. PMID 23238013 DOI: 10.1016/j.ccr.2012.11.005  0.84
2012 Wallez Y, Mace PD, Pasquale EB, Riedl SJ. NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer. Genes & Cancer. 3: 382-93. PMID 23226576 DOI: 10.1177/1947601912460050  0.84
2012 Noberini R, Koolpe M, Lamberto I, Pasquale EB. Inhibition of Eph receptor-ephrin ligand interaction by tea polyphenols. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 66: 363-73. PMID 22750215 DOI: 10.1016/j.phrs.2012.05.010  0.84
2012 Noberini R, Rubio de la Torre E, Pasquale EB. Profiling Eph receptor expression in cells and tissues: a targeted mass spectrometry approach. Cell Adhesion & Migration. 6: 102-12. PMID 22568954 DOI: 10.4161/cam.19620  0.84
2012 Tognolini M, Incerti M, Hassan-Mohamed I, Giorgio C, Russo S, Bruni R, Lelli B, Bracci L, Noberini R, Pasquale EB, Barocelli E, Vicini P, Mor M, Lodola A. Structure-activity relationships and mechanism of action of Eph-ephrin antagonists: interaction of cholanic acid with the EphA2 receptor. Chemmedchem. 7: 1071-83. PMID 22529030 DOI: 10.1002/cmdc.201200102  0.84
2012 Lamberto I, Qin H, Noberini R, Premkumar L, Bourgin C, Riedl SJ, Song J, Pasquale EB. Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor. The Biochemical Journal. 445: 47-56. PMID 22489865 DOI: 10.1042/BJ20120408  0.84
2012 Wang S, Placzek WJ, Stebbins JL, Mitra S, Noberini R, Koolpe M, Zhang Z, Dahl R, Pasquale EB, Pellecchia M. Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells. Journal of Medicinal Chemistry. 55: 2427-36. PMID 22329578 DOI: 10.1021/jm201743s  0.84
2012 Lisabeth EM, Fernandez C, Pasquale EB. Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms. Biochemistry. 51: 1464-75. PMID 22242939 DOI: 10.1021/bi2014079  0.84
2012 Noberini R, Lamberto I, Pasquale EB. Targeting Eph receptors with peptides and small molecules: progress and challenges. Seminars in Cell & Developmental Biology. 23: 51-7. PMID 22044885 DOI: 10.1016/j.semcdb.2011.10.023  0.84
2011 Noberini R, Mitra S, Salvucci O, Valencia F, Duggineni S, Prigozhina N, Wei K, Tosato G, Huang Z, Pasquale EB. PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity. Plos One. 6: e28611. PMID 22194865 DOI: 10.1371/journal.pone.0028611  0.84
2011 Mace PD, Wallez Y, Dobaczewska MK, Lee JJ, Robinson H, Pasquale EB, Riedl SJ. NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling. Nature Structural & Molecular Biology. 18: 1381-7. PMID 22081014 DOI: 10.1038/nsmb.2152  0.84
2011 Ogawa K, Takemoto N, Ishii M, Pasquale EB, Nakajima T. Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium. Histochemistry and Cell Biology. 136: 617-36. PMID 21959989 DOI: 10.1007/s00418-011-0867-2  0.84
2011 Ishii M, Mueller I, Nakajima T, Pasquale EB, Ogawa K. EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes. Basic Research in Cardiology. 106: 1057-68. PMID 21892745 DOI: 10.1007/s00395-011-0219-3  0.84
2011 Murai KK, Pasquale EB. Eph receptors and ephrins in neuron-astrocyte communication at synapses. Glia. 59: 1567-78. PMID 21850709 DOI: 10.1002/glia.21226  0.84
2011 Noberini R, De SK, Zhang Z, Wu B, Raveendra-Panickar D, Chen V, Vazquez J, Qin H, Song J, Cosford ND, Pellecchia M, Pasquale EB. A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. Chemical Biology & Drug Design. 78: 667-78. PMID 21791013 DOI: 10.1111/j.1747-0285.2011.01199.x  0.84
2011 Prigozhina NL, Heisel A, Wei K, Noberini R, Hunter EA, Calzolari D, Seldeen JR, Pasquale EB, Ruiz-Lozano P, Mercola M, Price JH. Characterization of a novel angiogenic model based on stable, fluorescently labelled endothelial cell lines amenable to scale-up for high content screening. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 103: 467-81. PMID 21732911 DOI: 10.1042/BC20100146  0.84
2011 Cesa R, Premoselli F, Renna A, Ethell IM, Pasquale EB, Strata P. Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex. Plos One. 6: e19160. PMID 21559471 DOI: 10.1371/journal.pone.0019160  0.84
2011 Yang NY, Fernandez C, Richter M, Xiao Z, Valencia F, Tice DA, Pasquale EB. Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells. Cellular Signalling. 23: 201-12. PMID 20837138 DOI: 10.1016/j.cellsig.2010.09.004  0.84
2011 Biliran H, Jan Y, Chen R, Pasquale EB, Ruoslahti E. Protein kinase D is a positive regulator of Bit1 apoptotic function (The Journal OF Biological Chemistry (2008) 283 (28029-28037)) Journal of Biological Chemistry. 286: 7714. DOI: 10.1074/jbc.A110.803139  0.84
2010 Murai KK, Pasquale EB. Restraining stem cell niche plasticity: a new talent of Eph receptors. Cell Stem Cell. 7: 647-8. PMID 21112558 DOI: 10.1016/j.stem.2010.11.023  0.84
2010 Browne CD, Hoefer MM, Chintalapati SK, Cato MH, Wallez Y, Ostertag DV, Pasquale EB, Rickert RC. SHEP1 partners with CasL to promote marginal zone B-cell maturation. Proceedings of the National Academy of Sciences of the United States of America. 107: 18944-9. PMID 20956287 DOI: 10.1073/pnas.1007558107  0.84
2010 Wang L, Vervoort V, Wallez Y, Coré N, Cremer H, Pasquale EB. The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13201-10. PMID 20881139 DOI: 10.1523/JNEUROSCI.3289-10.2010  0.84
2010 Mitra S, Duggineni S, Koolpe M, Zhu X, Huang Z, Pasquale EB. Structure-activity relationship analysis of peptides targeting the EphA2 receptor. Biochemistry. 49: 6687-95. PMID 20677833 DOI: 10.1021/bi1006223  0.84
2010 Yang NY, Lopez-Bergami P, Goydos JS, Yip D, Walker AM, Pasquale EB, Ethell IM. The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand. Pigment Cell & Melanoma Research. 23: 684-7. PMID 20649938 DOI: 10.1111/j.1755-148X.2010.00745.x  0.84
2010 Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB. The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas. Cellular Signalling. 22: 1745-52. PMID 20603213 DOI: 10.1016/j.cellsig.2010.06.015  0.84
2010 Huang FJ, You WK, Bonaldo P, Seyfried TN, Pasquale EB, Stallcup WB. Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse. Developmental Biology. 344: 1035-46. PMID 20599895 DOI: 10.1016/j.ydbio.2010.06.023  0.84
2010 Pasquale EB. Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nature Reviews. Cancer. 10: 165-80. PMID 20179713 DOI: 10.1038/nrc2806  0.84
2010 Bouvier D, Tremblay ME, Riad M, Corera AT, Gingras D, Horn KE, Fotouhi M, Girard M, Murai KK, Kennedy TE, McPherson PS, Pasquale EB, Fon EA, Doucet G. EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain. Journal of Neurochemistry. 113: 153-65. PMID 20067584 DOI: 10.1111/j.1471-4159.2010.06582.x  0.84
2010 Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nature Neuroscience. 13: 163-72. PMID 20062052 DOI: 10.1038/nn.2477  0.84
2010 Qin H, Noberini R, Huan X, Shi J, Pasquale EB, Song J. Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity. The Journal of Biological Chemistry. 285: 644-54. PMID 19875447 DOI: 10.1074/jbc.M109.064824  0.84
2009 Noberini R, Pasquale EB. Proliferation and tumor suppression: not mutually exclusive for Eph receptors. Cancer Cell. 16: 452-4. PMID 19962662 DOI: 10.1016/j.ccr.2009.11.008  0.84
2009 Pasquale EB. Journal club. A biologist is gratified to find reconciliation for a conflicted receptor. Nature. 461: 149. PMID 19741666 DOI: 10.1038/461149e  0.84
2009 Filosa A, Paixão S, Honsek SD, Carmona MA, Becker L, Feddersen B, Gaitanos L, Rudhard Y, Schoepfer R, Klopstock T, Kullander K, Rose CR, Pasquale EB, Klein R. Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nature Neuroscience. 12: 1285-92. PMID 19734893 DOI: 10.1038/nn.2394  0.84
2009 Carmona MA, Murai KK, Wang L, Roberts AJ, Pasquale EB. Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport. Proceedings of the National Academy of Sciences of the United States of America. 106: 12524-9. PMID 19592509 DOI: 10.1073/pnas.0903328106  0.36
2009 Noren NK, Yang NY, Silldorff M, Mutyala R, Pasquale EB. Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor. The Biochemical Journal. 422: 433-42. PMID 19552627 DOI: 10.1042/BJ20090014  0.84
2009 Codeluppi S, Svensson CI, Hefferan MP, Valencia F, Silldorff MD, Oshiro M, Marsala M, Pasquale EB. The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1093-104. PMID 19176818 DOI: 10.1523/JNEUROSCI.4103-08.2009  0.84
2009 Tremblay ME, Riad M, Chierzi S, Murai KK, Pasquale EB, Doucet G. Developmental course of EphA4 cellular and subcellular localization in the postnatal rat hippocampus. The Journal of Comparative Neurology. 512: 798-813. PMID 19086003 DOI: 10.1002/cne.21922  0.84
2008 Noberini R, Koolpe M, Peddibhotla S, Dahl R, Su Y, Cosford ND, Roth GP, Pasquale EB. Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors. The Journal of Biological Chemistry. 283: 29461-72. PMID 18728010 DOI: 10.1074/jbc.M804103200  0.84
2008 Irie F, Okuno M, Matsumoto K, Pasquale EB, Yamaguchi Y. Heparan sulfate regulates ephrin-A3/EphA receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 12307-12. PMID 18715996 DOI: 10.1073/pnas.0801302105  0.84
2008 Qin H, Shi J, Noberini R, Pasquale EB, Song J. Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor. The Journal of Biological Chemistry. 283: 29473-84. PMID 18708347 DOI: 10.1074/jbc.M804114200  0.84
2008 Biliran H, Jan Y, Chen R, Pasquale EB, Ruoslahti E. Protein kinase D is a positive regulator of Bit1 apoptotic function. The Journal of Biological Chemistry. 283: 28029-37. PMID 18703509 DOI: 10.1074/jbc.M803139200  0.84
2008 Bouvier D, Corera AT, Tremblay ME, Riad M, Chagnon M, Murai KK, Pasquale EB, Fon EA, Doucet G. Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain. Journal of Neurochemistry. 106: 682-95. PMID 18410519 DOI: 10.1111/j.1471-4159.2008.05416.x  0.84
2008 Murai KK, Pasquale EB. Neuroscience. Axons seek neighborly advice. Science (New York, N.Y.). 320: 185-6. PMID 18403698 DOI: 10.1126/science.1157605  0.84
2008 Pasquale EB. Eph-ephrin bidirectional signaling in physiology and disease. Cell. 133: 38-52. PMID 18394988 DOI: 10.1016/j.cell.2008.03.011  0.84
2008 Vervoort VS, Lu M, Valencia F, Lesperance J, Breier G, Oshima R, Pasquale EB. A novel Flk1-TVA transgenic mouse model for gene delivery to angiogenic vasculature. Transgenic Research. 17: 403-15. PMID 18027100 DOI: 10.1007/s11248-007-9156-1  0.84
2008 Leone M, Yu EC, Liddington RC, Pasquale EB, Pellecchia M. The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies. Biopolymers. 89: 86-92. PMID 17922498 DOI: 10.1002/bip.20862  0.84
2007 Richter M, Murai KK, Bourgin C, Pak DT, Pasquale EB. The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14205-15. PMID 18094260 DOI: 10.1523/JNEUROSCI.2746-07.2007  0.84
2007 Chrencik JE, Brooun A, Recht MI, Nicola G, Davis LK, Abagyan R, Widmer H, Pasquale EB, Kuhn P. Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. The Journal of Biological Chemistry. 282: 36505-13. PMID 17897949 DOI: 10.1074/jbc.M706340200  0.84
2007 Bourgin C, Murai KK, Richter M, Pasquale EB. The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways. The Journal of Cell Biology. 178: 1295-307. PMID 17875741 DOI: 10.1083/jcb.200610139  0.84
2007 Noren NK, Pasquale EB. Paradoxes of the EphB4 receptor in cancer. Cancer Research. 67: 3994-7. PMID 17483308 DOI: 10.1158/0008-5472.CAN-07-0525  0.84
2007 Tremblay ME, Riad M, Bouvier D, Murai KK, Pasquale EB, Descarries L, Doucet G. Localization of EphA4 in axon terminals and dendritic spines of adult rat hippocampus. The Journal of Comparative Neurology. 501: 691-702. PMID 17299751 DOI: 10.1002/cne.21263  0.84
2007 Vervoort VS, Roselli S, Oshima RG, Pasquale EB. Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling. Gene. 391: 161-70. PMID 17270363 DOI: 10.1016/j.gene.2006.12.016  0.84
2006 Kasemeier-Kulesa JC, Bradley R, Pasquale EB, Lefcort F, Kulesa PM. Eph/ephrins and N-cadherin coordinate to control the pattern of sympathetic ganglia. Development (Cambridge, England). 133: 4839-47. PMID 17108003 DOI: 10.1242/dev.02662  0.84
2006 Nefzi A, Hoesl CE, Pinilla C, Kauffman GB, Maggiora GM, Pasquale E, Houghten RA. Synthesis of platinum(II) chiral tetraamine coordination complexes. Journal of Combinatorial Chemistry. 8: 780-3. PMID 16961414 DOI: 10.1021/cc060045h  0.84
2006 Yang NY, Pasquale EB, Owen LB, Ethell IM. The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization. The Journal of Biological Chemistry. 281: 32574-86. PMID 16950769 DOI: 10.1074/jbc.M604338200  0.84
2006 Noren NK, Foos G, Hauser CA, Pasquale EB. The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Nature Cell Biology. 8: 815-25. PMID 16862147 DOI: 10.1038/ncb1438  0.84
2006 Dail M, Richter M, Godement P, Pasquale EB. Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsion. Journal of Cell Science. 119: 1244-54. PMID 16522685 DOI: 10.1242/jcs.02842  0.84
2006 Chrencik JE, Brooun A, Recht MI, Kraus ML, Koolpe M, Kolatkar AR, Bruce RH, Martiny-Baron G, Widmer H, Pasquale EB, Kuhn P. Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity. Structure (London, England : 1993). 14: 321-30. PMID 16472751 DOI: 10.1016/j.str.2005.11.011  0.84
2006 Ogawa K, Wada H, Okada N, Harada I, Nakajima T, Pasquale EB, Tsuyama S. EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. Journal of Cell Science. 119: 559-70. PMID 16443753 DOI: 10.1242/jcs.02777  0.84
2006 Derunes C, Burgess R, Iraheta E, Kellerer R, Becherer K, Gessner CR, Li S, Hewitt K, Vuori K, Pasquale EB, Woods VL, Ely KR. Molecular determinants for interaction of SHEP1 with Cas localize to a highly solvent-protected region in the complex. Febs Letters. 580: 175-8. PMID 16364304 DOI: 10.1016/j.febslet.2005.11.070  0.84
2005 Pasquale EB. Eph receptor signalling casts a wide net on cell behaviour. Nature Reviews. Molecular Cell Biology. 6: 462-75. PMID 15928710 DOI: 10.1038/nrm1662  0.84
2005 Ethell IM, Pasquale EB. Molecular mechanisms of dendritic spine development and remodeling. Progress in Neurobiology. 75: 161-205. PMID 15882774 DOI: 10.1016/j.pneurobio.2005.02.003  0.84
2005 Murai KK, Pasquale EB. New exchanges in eph-dependent growth cone dynamics. Neuron. 46: 161-3. PMID 15848793 DOI: 10.1016/j.neuron.2005.04.004  0.84
2005 Irie F, Okuno M, Pasquale EB, Yamaguchi Y. EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1. Nature Cell Biology. 7: 501-9. PMID 15821731 DOI: 10.1038/ncb1252  0.84
2005 Koolpe M, Burgess R, Dail M, Pasquale EB. EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity. The Journal of Biological Chemistry. 280: 17301-11. PMID 15722342 DOI: 10.1074/jbc.M500363200  0.84
2005 Miao H, Strebhardt K, Pasquale EB, Shen TL, Guan JL, Wang B. Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases. The Journal of Biological Chemistry. 280: 923-32. PMID 15536074 DOI: 10.1074/jbc.M411383200  0.84
2004 Dail M, Kalo MS, Seddon JA, Côté JF, Vuori K, Pasquale EB. SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases. The Journal of Biological Chemistry. 279: 41892-902. PMID 15272013 DOI: 10.1074/jbc.M402929200  0.84
2004 Murai KK, Pasquale EB. Eph receptors, ephrins, and synaptic function. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 304-14. PMID 15271258 DOI: 10.1177/1073858403262221  0.84
2004 Yamaguchi Y, Pasquale EB. Eph receptors in the adult brain. Current Opinion in Neurobiology. 14: 288-96. PMID 15194108 DOI: 10.1016/j.conb.2004.04.003  0.84
2004 Person AL, Cerretti DP, Pasquale EB, Rubel EW, Cramer KS. Tonotopic gradients of Eph family proteins in the chick nucleus laminaris during synaptogenesis. Journal of Neurobiology. 60: 28-39. PMID 15188270 DOI: 10.1002/neu.10330  0.84
2004 Pasquale EB. Eph-ephrin promiscuity is now crystal clear. Nature Neuroscience. 7: 417-8. PMID 15114347 DOI: 10.1038/nn0504-417  0.84
2004 Noren NK, Pasquale EB. Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins. Cellular Signalling. 16: 655-66. PMID 15093606 DOI: 10.1016/j.cellsig.2003.10.006  0.84
2004 Noren NK, Lu M, Freeman AL, Koolpe M, Pasquale EB. Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 101: 5583-8. PMID 15067119 DOI: 10.1073/pnas.0401381101  0.84
2004 Zisch AH, Zeisberger SM, Ehrbar M, Djonov V, Weber CC, Ziemiecki A, Pasquale EB, Hubbell JA. Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Biomaterials. 25: 3245-57. PMID 14980419 DOI: 10.1016/j.biomaterials.2003.10.015  0.84
2004 Eberhart J, Barr J, O'Connell S, Flagg A, Swartz ME, Cramer KS, Tosney KW, Pasquale EB, Krull CE. Ephrin-A5 exerts positive or inhibitory effects on distinct subsets of EphA4-positive motor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1070-8. PMID 14762125 DOI: 10.1523/JNEUROSCI.4719-03.2004  0.84
2003 Murai KK, Nguyen LN, Koolpe M, McLennan R, Krull CE, Pasquale EB. Targeting the EphA4 receptor in the nervous system with biologically active peptides. Molecular and Cellular Neurosciences. 24: 1000-11. PMID 14697664 DOI: 10.1016/j.mcn.2003.08.006  0.84
2003 Murai KK, Pasquale EB. 'Eph'ective signaling: forward, reverse and crosstalk. Journal of Cell Science. 116: 2823-32. PMID 12808016 DOI: 10.1242/jcs.00625  0.84
2003 Murai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB. Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling. Nature Neuroscience. 6: 153-60. PMID 12496762 DOI: 10.1038/nn994  0.84
2002 Koolpe M, Dail M, Pasquale EB. An ephrin mimetic peptide that selectively targets the EphA2 receptor. The Journal of Biological Chemistry. 277: 46974-9. PMID 12351647 DOI: 10.1074/jbc.M208495200  0.84
2002 St John JA, Pasquale EB, Key B. EphA receptors and ephrin-A ligands exhibit highly regulated spatial and temporal expression patterns in the developing olfactory system. Brain Research. Developmental Brain Research. 138: 1-14. PMID 12234653 DOI: 10.1016/S0165-3806(02)00454-6  0.84
2002 Cramer KS, Karam SD, Bothwell M, Cerretti DP, Pasquale EB, Rubel EW. Expression of EphB receptors and EphrinB ligands in the developing chick auditory brainstem. The Journal of Comparative Neurology. 452: 51-64. PMID 12205709 DOI: 10.1002/cne.10399  0.84
2002 Eberhart J, Swartz ME, Koblar SA, Pasquale EB, Krull CE. EphA4 constitutes a population-specific guidance cue for motor neurons. Developmental Biology. 247: 89-101. PMID 12074554 DOI: 10.1006/dbio.2002.0695  0.84
2002 Karam SD, Dottori M, Ogawa K, Henderson JT, Boyd AW, Pasquale EB, Bothwell M. EphA4 is not required for Purkinje cell compartmentation. Brain Research. Developmental Brain Research. 135: 29-38. PMID 11978390 DOI: 10.1016/S0165-3806(02)00278-X  0.84
2002 Murai KK, Pasquale EB. Can Eph receptors stimulate the mind? Neuron. 33: 159-62. PMID 11804564 DOI: 10.1016/S0896-6273(02)00565-2  0.84
2002 Zou JX, Liu Y, Pasquale EB, Ruoslahti E. Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity. The Journal of Biological Chemistry. 277: 1824-7. PMID 11682467 DOI: 10.1074/jbc.M103133200  0.84
2001 Swartz ME, Eberhart J, Pasquale EB, Krull CE. EphA4/ephrin-A5 interactions in muscle precursor cell migration in the avian forelimb. Development (Cambridge, England). 128: 4669-80. PMID 11731448  0.84
2001 Ethell IM, Irie F, Kalo MS, Couchman JR, Pasquale EB, Yamaguchi Y. EphB/syndecan-2 signaling in dendritic spine morphogenesis. Neuron. 31: 1001-13. PMID 11580899 DOI: 10.1016/S0896-6273(01)00440-8  0.84
2001 Yu HH, Zisch AH, Dodelet VC, Pasquale EB. Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor. Oncogene. 20: 3995-4006. PMID 11494128 DOI: 10.1038/sj.onc.1204524  0.84
2001 Kalo MS, Yu HH, Pasquale EB. In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue. The Journal of Biological Chemistry. 276: 38940-8. PMID 11466320 DOI: 10.1074/jbc.M105815200  0.84
2001 Menzel P, Valencia F, Godement P, Dodelet VC, Pasquale EB. Ephrin-A6, a new ligand for EphA receptors in the developing visual system. Developmental Biology. 230: 74-88. PMID 11161563 DOI: 10.1006/dbio.2000.0109  0.84
2000 Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, Pasquale EB. The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene. 19: 6043-52. PMID 11146556 DOI: 10.1038/sj.onc.1204004  0.84
2000 Dodelet VC, Pasquale EB. Eph receptors and ephrin ligands: embryogenesis to tumorigenesis. Oncogene. 19: 5614-9. PMID 11114742 DOI: 10.1038/sj.onc.1203856  0.84
2000 Cramer KS, Rosenberger MH, Frost DM, Cochran SL, Pasquale EB, Rubel EW. Developmental regulation of EphA4 expression in the chick auditory brainstem. The Journal of Comparative Neurology. 426: 270-8. PMID 10982468 DOI: 10.1002/1096-9861(20001016)426:2<270::AID-CNE8>3.0.CO;2-8  0.84
2000 Pasquale E. Neurobiology. Turning attraction into repulsion. Science (New York, N.Y.). 289: 1308-10. PMID 10979856 DOI: 10.1126/science.289.5483.1308  0.84
2000 Barritt DS, Pearn MT, Zisch AH, Lee SS, Javier RT, Pasquale EB, Stallcup WB. The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2. Journal of Cellular Biochemistry. 79: 213-24. PMID 10967549 DOI: 10.1002/1097-4644(20001101)79:2<213::AID-JCB50>3.0.CO;2-G  0.84
2000 Karam SD, Burrows RC, Logan C, Koblar S, Pasquale EB, Bothwell M. Eph receptors and ephrins in the developing chick cerebellum: relationship to sagittal patterning and granule cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6488-500. PMID 10964955  0.84
2000 Eberhart J, Swartz M, Koblar SA, Pasquale EB, Tanaka H, Krull CE. Expression of EphA4, ephrin-A2 and ephrin-A5 during axon outgrowth to the hindlimb indicates potential roles in pathfinding. Developmental Neuroscience. 22: 237-50. PMID 10894987  0.84
2000 Koblar SA, Krull CE, Pasquale EB, McLennan R, Peale FD, Cerretti DP, Bothwell M. Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite. Journal of Neurobiology. 42: 437-47. PMID 10699981 DOI: 10.1002/(SICI)1097-4695(200003)42:4<437::AID-NEU5>3.0.CO;2-O  0.84
2000 Küry P, Gale N, Connor R, Pasquale E, Guthrie S. Eph receptors and ephrin expression in cranial motor neurons and the branchial arches of the chick embryo. Molecular and Cellular Neurosciences. 15: 123-40. PMID 10673322 DOI: 10.1006/mcne.1999.0812  0.84
2000 Zisch AH, Pazzagli C, Freeman AL, Schneller M, Hadman M, Smith JW, Ruoslahti E, Pasquale EB. Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses. Oncogene. 19: 177-87. PMID 10644995 DOI: 10.1038/sj.onc.1203304  0.84
1999 Kalo MS, Pasquale EB. Multiple in vivo tyrosine phosphorylation sites in EphB receptors. Biochemistry. 38: 14396-408. PMID 10572014 DOI: 10.1021/bi991628t  0.84
1999 Zou JX, Wang B, Kalo MS, Zisch AH, Pasquale EB, Ruoslahti E. An Eph receptor regulates integrin activity through R-Ras. Proceedings of the National Academy of Sciences of the United States of America. 96: 13813-8. PMID 10570155 DOI: 10.1073/pnas.96.24.13813  0.84
1999 Kalo MS, Pasquale EB. Signal transfer by Eph receptors. Cell and Tissue Research. 298: 1-9. PMID 10555534 DOI: 10.1007/PL00008807  0.84
1999 Dodelet VC, Pazzagli C, Zisch AH, Hauser CA, Pasquale EB. A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A. The Journal of Biological Chemistry. 274: 31941-6. PMID 10542222 DOI: 10.1074/jbc.274.45.31941  0.84
1999 Rogers JH, Ciossek T, Menzel P, Pasquale EB. Eph receptors and ephrins demarcate cerebellar lobules before and during their formation. Mechanisms of Development. 87: 119-28. PMID 10495276 DOI: 10.1016/S0925-4773(99)00154-9  0.84
1998 Zisch AH, Kalo MS, Chong LD, Pasquale EB. Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region. Oncogene. 16: 2657-70. PMID 9632142 DOI: 10.1038/sj.onc.1201823  0.84
1998 Connor RJ, Menzel P, Pasquale EB. Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system. Developmental Biology. 193: 21-35. PMID 9466885 DOI: 10.1006/dbio.1997.8786  0.84
1997 Martone ME, Holash JA, Bayardo A, Pasquale EB, Ellisman MH. Immunolocalization of the receptor tyrosine kinase EphA4 in the adult rat central nervous system. Brain Research. 771: 238-50. PMID 9401744 DOI: 10.1016/S0006-8993(97)00792-0  0.84
1997 Monschau B, Kremoser C, Ohta K, Tanaka H, Kaneko T, Yamada T, Handwerker C, Hornberger MR, Löschinger J, Pasquale EB, Siever DA, Verderame MF, Müller BK, Bonhoeffer F, Drescher U. Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons. The Embo Journal. 16: 1258-67. PMID 9135142 DOI: 10.1093/emboj/16.6.1258  0.84
1997 Holash JA, Soans C, Chong LD, Shao H, Dixit VM, Pasquale EB. Reciprocal expression of the Eph receptor Cek5 and its ligand(s) in the early retina. Developmental Biology. 182: 256-69. PMID 9070326 DOI: 10.1006/dbio.1996.8496  0.84
1995 Brambilla R, Schnapp A, Casagranda F, Labrador JP, Bergemann AD, Flanagan JG, Pasquale EB, Klein R. Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. The Embo Journal. 14: 3116-26. PMID 7621826  0.84
1993 Patstone G, Pasquale EB, Maher PA. Different members of the fibroblast growth factor receptor family are specific to distinct cell types in the developing chicken embryo. Developmental Biology. 155: 107-23. PMID 8416827 DOI: 10.1006/dbio.1993.1011  0.84
1992 Pasquale EB, Deerinck TJ, Singer SJ, Ellisman MH. Cek5, a membrane receptor-type tyrosine kinase, is in neurons of the embryonic and postnatal avian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3956-67. PMID 1403093  0.84
1989 Pasquale EB, Singer SJ. Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library. Proceedings of the National Academy of Sciences of the United States of America. 86: 5449-53. PMID 2473471  0.84
1989 Maher PA, Pasquale EB. Heat shock induces protein tyrosine phosphorylation in cultured cells. The Journal of Cell Biology. 108: 2029-35. PMID 2472399  0.84
1988 Pasquale EB, Maher PA, Singer SJ. Comparative study of the tyrosine phosphorylation of proteins in Swiss 3T3 fibroblasts stimulated by a variety of mitogenic agents. Journal of Cellular Physiology. 137: 146-56. PMID 2459139 DOI: 10.1002/jcp.1041370118  0.84
1988 Maher PA, Pasquale EB. Tyrosine phosphorylated proteins in different tissues during chick embryo development. The Journal of Cell Biology. 106: 1747-55. PMID 2453521  0.84
1986 Karpen JW, Sachs AB, Pasquale EB, Hess GP. Spectrophotometric detection of monovalent cation flux in cells: fluorescence microscope measurement of acetylcholine receptor-mediated ion flux in PC-12 cells. Analytical Biochemistry. 157: 353-9. PMID 3777439 DOI: 10.1016/0003-2697(86)90637-8  0.84
1986 Pasquale EB, Udgaonkar JB, Hess GP. Single-channel current recordings of acetylcholine receptors in electroplax isolated from the Electrophorus electricus Main and Sachs' electric organs. The Journal of Membrane Biology. 93: 195-204. PMID 2433452 DOI: 10.1007/BF01870811  0.84
1986 Pasquale EB, Maher PA, Singer SJ. Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 83: 5507-11. PMID 2426700  0.84
1985 Maher PA, Pasquale EB, Wang JY, Singer SJ. Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 6576-80. PMID 2413441  0.84
1985 Cash DJ, Aoshima H, Pasquale EB, Hess GP. Acetylcholine-receptor-mediated ion fluxes in Electrophorus electricus and Torpedo california membrane vesicles. Reviews of Physiology, Biochemistry and Pharmacology. 102: 73-117. PMID 2412273  0.84
1983 Pasquale EB, Takeyasu K, Udgaonkar JB, Cash DJ, Severski MC, Hess GP. Acetylcholine receptor: evidence for a regulatory binding site in investigations of suberyldicholine-induced transmembrane ion flux in Electrophorus electricus membrane vesicles. Biochemistry. 22: 5967-73. PMID 6661420  0.84
1983 Sachs AB, Leprince P, Karpen JW, Pasquale EB, Abood LG, Hess GP. Phencyclidine inhibition of the acetylcholine receptor: measurement of cation flux in a sympathetic neuronal cell line using 22Na+ and spectroscopic detection of Cs+. Archives of Biochemistry and Biophysics. 225: 500-4. PMID 6625597 DOI: 10.1016/0003-9861(83)90059-0  0.84
1983 Karpen JW, Sachs AB, Cash DJ, Pasquale EB, Hess GP. Direct spectrophotometric detection of cation flux in membrane vesicles: stopped-flow measurements of acetylcholine-receptor-mediated ion flux. Analytical Biochemistry. 135: 83-94. PMID 6230951 DOI: 10.1016/0003-2697(83)90734-0  0.84
1982 Hess GP, Pasquale EB, Walker JW, McNamee MG. Comparison of acetylcholine receptor-controlled cation flux in membrane vesicles from Torpedo californica and Electrophorus electricus: chemical kinetic measurements in the millisecond region. Proceedings of the National Academy of Sciences of the United States of America. 79: 963-7. PMID 6951180  0.84
1982 Hess GP, Pasquale EB, Karpen JW, Sachs AB, Takeyasu K, Cash DJ. Acetylcholine receptor-controlled ion translocation. A comparison of the effects of suberyldicholine, carbamoylcholine, and acetylcholine. Biochemical and Biophysical Research Communications. 107: 1583-8. PMID 6291537 DOI: 10.1016/S0006-291X(82)80181-2  0.84
1981 Walker JW, McNamee MG, Pasquale E, Cash DJ, Hess GP. Acetylcholine receptor inactivation in Torpedo californica electroplax membrane vesicles. Detection of two processes in the millisecond and second time regions. Biochemical and Biophysical Research Communications. 100: 86-90. PMID 7259763 DOI: 10.1016/S0006-291X(81)80066-6  0.84
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