Frank Middleton - Publications

Affiliations: 
State University of New York, Upstate Medical University, Syracuse, NY 

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Hicks SD, Ignacio C, Gentile K, Middleton FA. Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment. Bmc Pediatrics. 16: 52. PMID 27105825 DOI: 10.1186/s12887-016-0586-x  1
2015 Ignacio C, Hicks SD, Burke P, Lewis L, Szombathyne-Meszaros Z, Middleton FA. Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain. Bmc Neuroscience. 16: 55. PMID 26341662 DOI: 10.1186/s12868-015-0195-x  1
2015 Simbiri KO, Smith NA, Otieno R, Wohlford EE, Daud II, Odada SP, Middleton F, Rochford R. Epstein-barr virus genetic variation in lymphoblastoid cell lines derived from kenyan pediatric population. Plos One. 10: e0125420. PMID 25933165 DOI: 10.1371/journal.pone.0125420  1
2015 Kates WR, Olszewski AK, Gnirke MH, Kikinis Z, Nelson J, Antshel KM, Fremont W, Radoeva PD, Middleton FA, Shenton ME, Coman IL. White matter microstructural abnormalities of the cingulum bundle in youths with 22q11.2 deletion syndrome: associations with medication, neuropsychological function, and prodromal symptoms of psychosis. Schizophrenia Research. 161: 76-84. PMID 25066496 DOI: 10.1016/j.schres.2014.07.010  1
2014 Radoeva PD, Coman IL, Salazar CA, Gentile KL, Higgins AM, Middleton FA, Antshel KM, Fremont W, Shprintzen RJ, Morrow BE, Kates WR. Association between autism spectrum disorder in individuals with velocardiofacial (22q11.2 deletion) syndrome and PRODH and COMT genotypes. Psychiatric Genetics. 24: 269-72. PMID 25325218 DOI: 10.1097/YPG.0000000000000062  1
2014 Melhem NM, Lu C, Dresbold C, Middleton FA, Klei L, Wood S, Faraone SV, Vinogradov S, Tiobech J, Yano V, Roeder K, Byerley W, Myles-Worsley M, Devlin B. Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 521-30. PMID 24980794 DOI: 10.1002/ajmg.b.32255  1
2014 Zhang-James Y, Yang L, Middleton FA, Yang L, Patak J, Faraone SV. Autism-related behavioral phenotypes in an inbred rat substrain. Behavioural Brain Research. 269: 103-14. PMID 24780868 DOI: 10.1016/j.bbr.2014.04.035  1
2014 Perlstein MD, Chohan MR, Coman IL, Antshel KM, Fremont WP, Gnirke MH, Kikinis Z, Middleton FA, Radoeva PD, Shenton ME, Kates WR. White matter abnormalities in 22q11.2 deletion syndrome: preliminary associations with the Nogo-66 receptor gene and symptoms of psychosis. Schizophrenia Research. 152: 117-23. PMID 24321711 DOI: 10.1016/j.schres.2013.11.015  1
2013 Zhang-James Y, Middleton FA, Faraone SV. Genetic architecture of Wistar-Kyoto rat and spontaneously hypertensive rat substrains from different sources. Physiological Genomics. 45: 528-38. PMID 23673728 DOI: 10.1152/physiolgenomics.00002.2013  1
2013 Myles-Worsley M, Tiobech J, Browning SR, Korn J, Goodman S, Gentile K, Melhem N, Byerley W, Faraone SV, Middleton FA. Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 87-95. PMID 23341099 DOI: 10.1002/ajmg.b.32125  1
2012 Cowley PM, Keslacy S, Middleton FA, DeRuisseau LR, Fernhall B, Kanaley JA, DeRuisseau KC. Functional and biochemical characterization of soleus muscle in Down syndrome mice: insight into the muscle dysfunction seen in the human condition. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 303: R1251-60. PMID 23115123 DOI: 10.1152/ajpregu.00312.2012  1
2012 Hicks SD, Lewis L, Ritchie J, Burke P, Abdul-Malak Y, Adackapara N, Canfield K, Shwarts E, Gentile K, Meszaros ZS, Middleton FA. Evaluation of cell proliferation, apoptosis, and DNA-repair genes as potential biomarkers for ethanol-induced CNS alterations. Bmc Neuroscience. 13: 128. PMID 23095216 DOI: 10.1186/1471-2202-13-128  1
2012 Cohen OS, Mccoy SY, Middleton FA, Bialosuknia S, Zhang-James Y, Liu L, Tsuang MT, Faraone SV, Glatt SJ. Transcriptomic analysis of postmortem brain identifies dysregulated splicing events in novel candidate genes for schizophrenia. Schizophrenia Research. 142: 188-99. PMID 23062752 DOI: 10.1016/j.schres.2012.09.015  1
2012 Cameron DA, Middleton FA, Chenn A, Olson EC. Hierarchical clustering of gene expression patterns in the Eomes + lineage of excitatory neurons during early neocortical development. Bmc Neuroscience. 13: 90. PMID 22852769 DOI: 10.1186/1471-2202-13-90  1
2012 Zhang-James Y, Middleton FA, Sagvolden T, Faraone SV. Differential expression of SLC9A9 and interacting molecules in the hippocampus of rat models for attention deficit/hyperactivity disorder. Developmental Neuroscience. 34: 218-27. PMID 22777493 DOI: 10.1159/000338813  1
2012 Middleton FA, Varlinskaya EI, Mooney SM. Molecular substrates of social avoidance seen following prenatal ethanol exposure and its reversal by social enrichment. Developmental Neuroscience. 34: 115-28. PMID 22572756 DOI: 10.1159/000337858  1
2012 Fanous AH, Middleton FA, Gentile K, Amdur RL, Maher BS, Zhao Z, Sun J, Medeiros H, Carvalho C, Ferreira SR, Macedo A, Knowles JA, Azevedo MH, Pato MT, Pato CN. Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 383-91. PMID 22461138 DOI: 10.1002/ajmg.b.32041  1
2012 Kumagai C, Kalman B, Middleton FA, Vyshkina T, Massa PT. Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects. Journal of Neuroimmunology. 246: 51-7. PMID 22458980 DOI: 10.1016/j.jneuroim.2012.03.003  1
2012 Stergiakouli E, Hamshere M, Holmans P, Langley K, Zaharieva I, Hawi Z, Kent L, Gill M, Williams N, Owen MJ, O'Donovan M, Thapar A. Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. The American Journal of Psychiatry. 169: 186-94. PMID 22420046 DOI: 10.1176/appi.ajp.2011.11040551  1
2012 Elia J, Glessner JT, Wang K, Takahashi N, Shtir CJ, Hadley D, Sleiman PM, Zhang H, Kim CE, Robison R, Lyon GJ, Flory JH, Bradfield JP, Imielinski M, Hou C, ... ... Middleton FA, et al. Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature Genetics. 44: 78-84. PMID 22138692 DOI: 10.1038/ng.1013  1
2011 Melhem N, Middleton F, McFadden K, Klei L, Faraone SV, Vinogradov S, Tiobech J, Yano V, Kuartei S, Roeder K, Byerley W, Devlin B, Myles-Worsley M. Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees. Biological Psychiatry. 70: 1115-21. PMID 21982423 DOI: 10.1016/j.biopsych.2011.08.009  1
2011 Sazonova NA, DasBanerjee T, Middleton FA, Gowtham S, Schuckers S, Faraone SV. Transcriptome-wide gene expression in a rat model of attention deficit hyperactivity disorder symptoms: rats developmentally exposed to polychlorinated biphenyls. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 898-912. PMID 21919189 DOI: 10.1002/ajmg.b.31230  1
2011 Zhang-James Y, DasBanerjee T, Sagvolden T, Middleton FA, Faraone SV. SLC9A9 mutations, gene expression, and protein-protein interactions in rat models of attention-deficit/hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 835-43. PMID 21858920 DOI: 10.1002/ajmg.b.31229  1
2011 Meszaros ZS, Dimmock JA, Ploutz-Snyder R, Chauhan SV, Abdul-Malak Y, Middleton FA, Batki SL. Accuracy of self-reported medical problems in patients with alcohol dependence and co-occurring schizophrenia or schizoaffective disorder. Schizophrenia Research. 132: 190-3. PMID 21852074 DOI: 10.1016/j.schres.2011.07.033  1
2011 Myles-Worsley M, Tiobech J, Blailes F, Middleton FA, Vinogradov S, Byerley W, Faraone SV. Familial transmission of schizophrenia in Palau: A 20-year genetic epidemiological study in three generations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 247-54. PMID 21294248 DOI: 10.1002/ajmg.b.31171  1
2011 Mick E, McGough JJ, Middleton FA, Neale B, Faraone SV. Genome-wide association study of blood pressure response to methylphenidate treatment of attention-deficit/hyperactivity disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 466-72. PMID 21130132 DOI: 10.1016/j.pnpbp.2010.11.037  1
2011 Lindke AL, Middleton FA, Miller MW. Corrigendum to Regulating the availability of transforming growth factor β1 in B104 neuroblastoma cells [Exp Neurol. 225, 1, (2010) 123-132] Experimental Neurology. 227: 236. DOI: 10.1016/j.expneurol.2010.10.005  1
2010 Siebert JR, Middleton FA, Stelzner DJ. Long descending cervical propriospinal neurons differ from thoracic propriospinal neurons in response to low thoracic spinal injury. Bmc Neuroscience. 11: 148. PMID 21092315 DOI: 10.1186/1471-2202-11-148  1
2010 Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, ... ... Middleton FA, et al. PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease. Science Translational Medicine. 2: 52ra73. PMID 20926834 DOI: 10.1126/scitranslmed.3001059  1
2010 Neale BM, Medland S, Ripke S, Anney RJ, Asherson P, Buitelaar J, Franke B, Gill M, Kent L, Holmans P, Middleton F, Thapar A, Lesch KP, Faraone SV, Daly M, et al. Case-control genome-wide association study of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 49: 906-20. PMID 20732627 DOI: 10.1016/j.jaac.2010.06.007  1
2010 Neale BM, Medland SE, Ripke S, Asherson P, Franke B, Lesch KP, Faraone SV, Nguyen TT, Schäfer H, Holmans P, Daly M, Steinhausen HC, Freitag C, Reif A, Renner TJ, ... ... Middleton F, et al. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 49: 884-97. PMID 20732625 DOI: 10.1016/j.jaac.2010.06.008  1
2010 Hicks SD, Middleton FA, Miller MW. Ethanol-induced methylation of cell cycle genes in neural stem cells. Journal of Neurochemistry. 114: 1767-80. PMID 20626555 DOI: 10.1111/j.1471-4159.2010.06886.x  1
2010 Lindke AL, Middleton FA, Miller MW. Regulating the availability of transforming growth factor ß1 in B104 neuroblastoma cells. Experimental Neurology. 225: 123-32. PMID 20547156 DOI: 10.1016/j.expneurol.2010.06.002  1
2010 Maier KG, Han X, Sadowitz B, Gentile KL, Middleton FA, Gahtan V. Thrombospondin-1: a proatherosclerotic protein augmented by hyperglycemia. Journal of Vascular Surgery. 51: 1238-47. PMID 20299182 DOI: 10.1016/j.jvs.2009.11.073  1
2010 Roessner V, Sagvolden T, Dasbanerjee T, Middleton FA, Faraone SV, Walaas SI, Becker A, Rothenberger A, Bock N. Methylphenidate normalizes elevated dopamine transporter densities in an animal model of the attention-deficit/hyperactivity disorder combined type, but not to the same extent in one of the attention-deficit/hyperactivity disorder inattentive type. Neuroscience. 167: 1183-91. PMID 20211696 DOI: 10.1016/j.neuroscience.2010.02.073  1
2010 Laiosa MD, Mills JH, Lai ZW, Singh KP, Middleton FA, Gasiewicz TA, Silverstone AE. Identification of stage-specific gene modulation during early thymocyte development by whole-genome profiling analysis after aryl hydrocarbon receptor activation. Molecular Pharmacology. 77: 773-83. PMID 20159946 DOI: 10.1124/mol.109.062497  1
2010 Berger DF, Lombardo JP, Peck JA, Faraone SV, Middleton FA, Youngetob SL. The effects of strain and prenatal nicotine exposure on ethanol consumption by adolescent male and female rats. Behavioural Brain Research. 210: 147-54. PMID 20138923 DOI: 10.1016/j.bbr.2010.01.047  1
2010 Coman IL, Gnirke MH, Middleton FA, Antshel KM, Fremont W, Higgins AM, Shprintzen RJ, Kates WR. The effects of gender and catechol O-methyltransferase (COMT) Val108/158Met polymorphism on emotion regulation in velo-cardio-facial syndrome (22q11.2 deletion syndrome): An fMRI study. Neuroimage. 53: 1043-50. PMID 20123031 DOI: 10.1016/j.neuroimage.2010.01.094  1
2009 Sagvolden T, Johansen EB, Wøien G, Walaas SI, Storm-Mathisen J, Bergersen LH, Hvalby O, Jensen V, Aase H, Russell VA, Killeen PR, Dasbanerjee T, Middleton FA, Faraone SV. The spontaneously hypertensive rat model of ADHD--the importance of selecting the appropriate reference strain. Neuropharmacology. 57: 619-26. PMID 19698722 DOI: 10.1016/j.neuropharm.2009.08.004  1
2009 Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Ruderfer DM, McQuillin A, Morris DW, Oĝdushlaine CT, Corvin A, Holmans PA, Oĝdonovan MC, MacGregor S, Gurling H, ... ... Middleton F, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Nature. 460: 748-752. PMID 19571811 DOI: 10.1038/nature08185  1
2009 Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. Plos Genetics. 5: e1000534. PMID 19557189 DOI: 10.1371/journal.pgen.1000534  1
2009 Damron TA, Zhang M, Pritchard MR, Middleton FA, Horton JA, Margulies BM, Strauss JA, Farnum CE, Spadaro JA. Microarray cluster analysis of irradiated growth plate zones following laser microdissection. International Journal of Radiation Oncology, Biology, Physics. 74: 949-56. PMID 19480974 DOI: 10.1016/j.ijrobp.2008.10.009  1
2009 Hanczko R, Fernandez DR, Doherty E, Qian Y, Vas G, Niland B, Telarico T, Garba A, Banerjee S, Middleton FA, Barrett D, Barcza M, Banki K, Landas SK, Perl A. Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine. The Journal of Clinical Investigation. 119: 1546-57. PMID 19436114 DOI: 10.1172/JCI35722  1
2009 Fernandez DR, Telarico T, Bonilla E, Li Q, Banerjee S, Middleton FA, Phillips PE, Crow MK, Oess S, Muller-Esterl W, Perl A. Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. Journal of Immunology (Baltimore, Md. : 1950). 182: 2063-73. PMID 19201859 DOI: 10.4049/jimmunol.0803600  1
2009 Middleton FA, Carrierfenster K, Mooney SM, Youngentob SL. Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats. Brain Research. 1252: 105-16. PMID 19063871 DOI: 10.1016/j.brainres.2008.11.023  1
2009 Fanous AH, Middleton F, Pato CN, Pato MT. Bipolar Disorder in the Era of Genomic Psychiatry Genomic and Personalized Medicine, Two-Vol Set. 1299-1311. DOI: 10.1016/B978-0-12-369420-1.00106-2  1
2008 Sagvolden T, Dasbanerjee T, Zhang-James Y, Middleton F, Faraone S. Behavioral and genetic evidence for a novel animal model of Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype. Behavioral and Brain Functions : Bbf. 4: 56. PMID 19046438 DOI: 10.1186/1744-9081-4-56  1
2008 DasBanerjee T, Middleton FA, Berger DF, Lombardo JP, Sagvolden T, Faraone SV. A comparison of molecular alterations in environmental and genetic rat models of ADHD: a pilot study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1554-63. PMID 18937310 DOI: 10.1002/ajmg.b.30877  1
2008 Mick E, Neale B, Middleton FA, McGough JJ, Faraone SV. Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1412-8. PMID 18821564 DOI: 10.1002/ajmg.b.30865  1
2008 Meguid MM, Glade MJ, Middleton FA. Weight regain after Roux-en-Y: a significant 20% complication related to PYY. Nutrition (Burbank, Los Angeles County, Calif.). 24: 832-42. PMID 18725080 DOI: 10.1016/j.nut.2008.06.027  1
2008 Shah G, Middleton FA, Gentile KL, Tripathi S, Bruch D, Maier KG, Kittur DS. Cyclosporine inhibition of angiogenesis involves the transcription factor HESR1. The Journal of Surgical Research. 149: 171-6. PMID 18694572 DOI: 10.1016/j.jss.2008.03.016  1
2008 Stone JL, O'Donovan MC, Gurling H, Kirov GK, Blackwood DHR, Corvin A, Craddock NJ, Gill M, Hultman CM, Lichtenstein P, McQuillin A, Pato CN, Ruderfer DM, Owen MJ, St Clair D, ... ... Middleton F, et al. Rare chromosomal deletions and duplications increase risk of schizophrenia Nature. 455: 237-241. PMID 18668038 DOI: 10.1038/nature07239  1
2008 Zhang M, Pritchard MR, Middleton FA, Horton JA, Damron TA. Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways. Bone. 43: 511-20. PMID 18579462 DOI: 10.1016/j.bone.2008.04.021  1
2008 Ross OA, Braithwaite AT, Skipper LM, Kachergus J, Hulihan MM, Middleton FA, Nishioka K, Fuchs J, Gasser T, Maraganore DM, Adler CH, Larvor L, Chartier-Harlin MC, Nilsson C, Langston JW, et al. Genomic investigation of alpha-synuclein multiplication and parkinsonism. Annals of Neurology. 63: 743-50. PMID 18571778 DOI: 10.1002/ana.21380  1
2008 Qian Y, Banerjee S, Grossman CE, Amidon W, Nagy G, Barcza M, Niland B, Karp DR, Middleton FA, Banki K, Perl A. Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing. The Biochemical Journal. 415: 123-34. PMID 18498245 DOI: 10.1042/BJ20080722  1
2008 Pullmann R, Bonilla E, Phillips PE, Middleton FA, Perl A. Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus. Arthritis and Rheumatism. 58: 532-40. PMID 18240231 DOI: 10.1002/art.23161  1
2007 Middleton FA, Rosenow C, Vailaya A, Kuchinsky A, Pato MT, Pato CN. Integrating genetic, functional genomic, and bioinformatics data in a systems biology approach to complex diseases: application to schizophrenia. Methods in Molecular Biology (Clifton, N.J.). 401: 337-64. PMID 18368374 DOI: 10.1007/978-1-59745-520-6_18  1
2007 Banerjee TD, Middleton F, Faraone SV. Environmental risk factors for attention-deficit hyperactivity disorder. Acta Paediatrica (Oslo, Norway : 1992). 96: 1269-74. PMID 17718779 DOI: 10.1111/j.1651-2227.2007.00430.x  1
2007 Wang Y, Zhang M, Middleton FA, Horton JA, Pritchard M, Spadaro JA, Farnum CE, Damron TA. Connective tissue growth factor and insulin-like growth factor 2 show upregulation in early growth plate radiorecovery response following irradiation. Cells, Tissues, Organs. 186: 192-203. PMID 17630476 DOI: 10.1159/000105673  1
2007 Guijarro A, Suzuki S, Chen C, Kirchner H, Middleton FA, Nadtochiy S, Brookes PS, Niijima A, Inui A, Meguid MM. Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1474-89. PMID 17626126 DOI: 10.1152/ajpregu.00171.2007  1
2007 Zhang M, Wang Y, Middleton FA, Horton JA, Farnum CE, Damron TA. Growth plate zonal microarray analysis shows upregulation of extracellular matrix genes and downregulation of metalloproteinases and cathepsins following irradiation. Calcified Tissue International. 81: 26-38. PMID 17549535 DOI: 10.1007/s00223-007-9025-1  1
2007 Fuchs J, Nilsson C, Kachergus J, Munz M, Larsson EM, Schüle B, Langston JW, Middleton FA, Ross OA, Hulihan M, Gasser T, Farrer MJ. Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology. 68: 916-22. PMID 17251522 DOI: 10.1212/01.wnl.0000254458.17630.c5  1
2007 Milgrom E, Diab H, Middleton F, Kane PM. Loss of vacuolar proton-translocating ATPase activity in yeast results in chronic oxidative stress. The Journal of Biological Chemistry. 282: 7125-36. PMID 17215245 DOI: 10.1074/jbc.M608293200  1
2006 Perl A, Qian Y, Chohan KR, Shirley CR, Amidon W, Banerjee S, Middleton FA, Conkrite KL, Barcza M, Gonchoroff N, Suarez SS, Banki K. Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa. Proceedings of the National Academy of Sciences of the United States of America. 103: 14813-8. PMID 17003133 DOI: 10.1073/pnas.0602678103  1
2006 Zraly CB, Middleton FA, Dingwall AK. Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function. The Journal of Biological Chemistry. 281: 35305-15. PMID 16990270 DOI: 10.1074/jbc.M607806200  1
2006 Bui CJ, McGann AC, Middleton FA, Beaman-Hall CM, Vallano ML. Transcriptional profiling of depolarization-dependent phenotypic alterations in primary cultures of developing granule neurons. Brain Research. 1119: 13-25. PMID 16989786 DOI: 10.1016/j.brainres.2006.08.043  1
2006 Miller MW, Mooney SM, Middleton FA. Transforming growth factor beta1 and ethanol affect transcription and translation of genes and proteins for cell adhesion molecules in B104 neuroblastoma cells. Journal of Neurochemistry. 97: 1182-90. PMID 16686695 DOI: 10.1111/j.1471-4159.2006.03858.x  1
2006 Hoopes RR, Middleton FA, Sen S, Hueber PA, Reid R, Bushinsky DA, Scheinman SJ. Isolation and confirmation of a calcium excretion quantitative trait locus on chromosome 1 in genetic hypercalciuric stone-forming congenic rats. Journal of the American Society of Nephrology : Jasn. 17: 1292-304. PMID 16611718 DOI: 10.1681/ASN.2005080828  1
2006 Vallano ML, Beaman-Hall CM, Bui CJ, Middleton FA. Depolarization and Ca(2+) down regulate CB1 receptors and CB1-mediated signaling in cerebellar granule neurons. Neuropharmacology. 50: 651-60. PMID 16412482 DOI: 10.1016/j.neuropharm.2005.11.012  1
2006 Middleton FA, Trauzzi MG, Shrimpton AE, Gentile KL, Morley CP, Medeiros H, Pato MT, Pato CN. Complete maternal uniparental isodisomy of chromosome 4 in a subject with major depressive disorder detected by high density SNP genotyping arrays. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 28-32. PMID 16331669 DOI: 10.1002/ajmg.b.30250  1
2005 Cameron DA, Gentile KL, Middleton FA, Yurco P. Gene expression profiles of intact and regenerating zebrafish retina. Molecular Vision. 11: 775-91. PMID 16205622  1
2005 Petryshen TL, Middleton FA, Tahl AR, Rockwell GN, Purcell S, Aldinger KA, Kirby A, Morley CP, McGann L, Gentile KL, Waggoner SG, Medeiros HM, Carvalho C, Macedo A, Albus M, et al. Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia. Molecular Psychiatry. 10: 1074-88, 1057. PMID 16172613 DOI: 10.1038/sj.mp.4001739  1
2005 Zhang Y, James M, Middleton FA, Davis RL. Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 137: 5-16. PMID 15965975 DOI: 10.1002/ajmg.b.30195  1
2005 Middleton FA, Pato CN, Gentile KL, McGann L, Brown AM, Trauzzi M, Diab H, Morley CP, Medeiros H, Macedo A, Azevedo MH, Pato MT. Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 136: 12-25. PMID 15892139 DOI: 10.1002/ajmg.b.30171  1
2005 Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K. Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 974-83. PMID 15726117 DOI: 10.1038/sj.npp.1300674  1
2005 Pato CN, Middleton FA, Gentile KL, Morley CP, Medeiros H, Macedo A, Azevedo MH, Pato MT. Genetic linkage of bipolar disorder to chromosome 6q22 is a consistent finding in Portuguese subpopulations and may generalize to broader populations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 119-21. PMID 15704217 DOI: 10.1002/ajmg.b.30159  1
2005 Petryshen TL, Middleton FA, Kirby A, Aldinger KA, Purcell S, Tahl AR, Morley CP, McGann L, Gentile KL, Rockwell GN, Medeiros HM, Carvalho C, Macedo A, Dourado A, Valente J, et al. Support for involvement of neuregulin 1 in schizophrenia pathophysiology. Molecular Psychiatry. 10: 366-74, 328. PMID 15545978 DOI: 10.1038/sj.mp.4001608  1
2005 Petryshen TL, Middleton FA, Tahl AR, Rockwell GN, Purcell S, Aldinger KA, Kirby A, Morley CP, McGann L, Gentile KL, Waggoner SG, Medeiros HM, Carvalho C, Macedo A, Albus M, et al. Linkage disequilibrium and haplotype structure of five GABAA receptor subunit genes investigated for association with schizophrenia Molecular Psychiatry. 10: 1057. DOI: 10.1038/sj.mp.4001770  1
2004 Pongrac JL, Middleton FA, Peng L, Lewis DA, Levitt P, Mirnics K. Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia. Biological Psychiatry. 56: 943-50. PMID 15601604 DOI: 10.1016/j.biopsych.2004.09.005  1
2004 Wang Y, Middleton F, Horton JA, Reichel L, Farnum CE, Damron TA. Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways. Bone. 35: 1273-93. PMID 15589209 DOI: 10.1016/j.bone.2004.09.009  1
2004 Ramos EJ, Middleton FA, Laviano A, Sato T, Romanova I, Das UN, Chen C, Qi Y, Meguid MM. Effects of omega-3 fatty acid supplementation on tumor-bearing rats. Journal of the American College of Surgeons. 199: 716-23. PMID 15501111 DOI: 10.1016/j.jamcollsurg.2004.07.014  1
2004 Xu Y, Ramos EJ, Middleton F, Romanova I, Quinn R, Chen C, Das U, Inui A, Meguid MM. Gene expression profiles post Roux-en-Y gastric bypass. Surgery. 136: 246-52. PMID 15300187 DOI: 10.1016/j.surg.2004.04.027  1
2004 Shrimpton AE, Levinsohn EM, Yozawitz JM, Packard DS, Cady RB, Middleton FA, Persico AM, Hootnick DR. A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. American Journal of Human Genetics. 75: 92-6. PMID 15146389 DOI: 10.1086/422015  1
2004 Middleton FA, Pato MT, Gentile KL, Morley CP, Zhao X, Eisener AF, Brown A, Petryshen TL, Kirby AN, Medeiros H, Carvalho C, Macedo A, Dourado A, Coelho I, Valente J, et al. Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22. American Journal of Human Genetics. 74: 886-97. PMID 15060841 DOI: 10.1086/420775  1
2004 Middleton FA, Ramos EJ, Xu Y, Diab H, Zhao X, Das UN, Meguid M. Application of genomic technologies: DNA microarrays and metabolic profiling of obesity in the hypothalamus and in subcutaneous fat. Nutrition (Burbank, Los Angeles County, Calif.). 20: 14-25. PMID 14698009 DOI: 10.1016/j.nut.2003.10.002  1
2003 Ramos EJ, Xu Y, Romanova I, Middleton F, Chen C, Quinn R, Inui A, Das U, Meguid MM. Is obesity an inflammatory disease? Surgery. 134: 329-35. PMID 12947337 DOI: 10.1067/msy.2003.267  1
2002 Pongrac J, Middleton FA, Lewis DA, Levitt P, Mirnics K. Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Neurochemical Research. 27: 1049-63. PMID 12462404 DOI: 10.1023/A:1020904821237  1
2002 Middleton FA, Strick PL. Basal-ganglia 'projections' to the prefrontal cortex of the primate. Cerebral Cortex (New York, N.Y. : 1991). 12: 926-35. PMID 12183392  1
2002 Menashe I, Man O, Lancet D, Gilad Y. Population differences in haplotype structure within a human olfactory receptor gene cluster. Human Molecular Genetics. 11: 1381-90. PMID 12023980 DOI: 10.1093/hmg/11.12.1381  1
2002 Middleton FA, Mirnics K, Pierri JN, Lewis DA, Levitt P. Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2718-29. PMID 11923437  1
2001 Mirnics K, Middleton FA, Lewis DA, Levitt P. Delineating novel signature patterns of altered gene expression in schizophrenia using gene microarrays. Thescientificworldjournal. 1: 114-6. PMID 12805694 DOI: 10.1100/tsw.2001.17  1
2001 Mirnics K, Middleton FA, Lewis DA, Levitt P. The human genome: gene expression profiling and schizophrenia. The American Journal of Psychiatry. 158: 1384. PMID 11532720 DOI: 10.1176/appi.ajp.158.9.1384  1
2001 Mirnics K, Middleton FA, Lewis DA, Levitt P. Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends in Neurosciences. 24: 479-86. PMID 11476888 DOI: 10.1016/S0166-2236(00)01862-2  1
2001 Mirnics K, Middleton FA, Stanwood GD, Lewis DA, Levitt P. Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Molecular Psychiatry. 6: 293-301. PMID 11326297 DOI: 10.1038/sj.mp.4000866  1
2001 Middleton FA, Strick PL. Cerebellar projections to the prefrontal cortex of the primate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 700-12. PMID 11160449  1
2000 Mirnics K, Middleton FA, Marquez A, Lewis DA, Levitt P. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron. 28: 53-67. PMID 11086983  1
2000 Middleton FA, Strick PL. Basal ganglia output and cognition: evidence from anatomical, behavioral, and clinical studies. Brain and Cognition. 42: 183-200. PMID 10744919 DOI: 10.1006/brcg.1999.1099  1
2000 Middleton FA, Strick PL. Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Research. Brain Research Reviews. 31: 236-50. PMID 10719151 DOI: 10.1016/S0165-0173(99)00040-5  1
1998 Middleton FA, Strick PL. Cerebellar output: motor and cognitive channels. Trends in Cognitive Sciences. 2: 348-54. PMID 21227231 DOI: 10.1016/S1364-6613(98)01220-0  1
1998 Middleton FA, Strick PL. The cerebellum: an overview. Trends in Cognitive Sciences. 2: 305-6. PMID 21227225  1
1998 Middleton FA, Strick PL. The cerebellum: an overview. Trends in Neurosciences. 21: 367-9. PMID 9735943 DOI: 10.1016/S1364-6613(98)01224-8  1
1997 Middleton FA, Strick PL. Cerebellar output channels. International Review of Neurobiology. 41: 61-82. PMID 9378611  1
1997 Middleton FA, Strick PL. New concepts about the organization of basal ganglia output. Advances in Neurology. 74: 57-68. PMID 9348402  1
1997 Middleton FA, Strick PL. Dentate output channels: motor and cognitive components. Progress in Brain Research. 114: 553-66. PMID 9193166  1
1996 Middleton FA, Strick PL. Basal ganglia and cerebellar output influences non-motor function. Molecular Psychiatry. 1: 429-33. PMID 9154241  1
1996 Middleton FA, Strick PL. The temporal lobe is a target of output from the basal ganglia. Proceedings of the National Academy of Sciences of the United States of America. 93: 8683-7. PMID 8710931 DOI: 10.1073/pnas.93.16.8683  1
1994 Middleton FA, Strick PL. Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function. Science (New York, N.Y.). 266: 458-61. PMID 7939688  1
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