| Year |
Citation |
Score |
| 2018 |
Lipscombe D, Wyllie DJ. Editorial overview: Ion channels Current Opinion in Physiology. 2: iv-vii. DOI: 10.1016/J.COPHYS.2018.02.012 |
0.331 |
|
| 2017 |
McQueen J, Ryan TJ, McKay S, Marwick KF, Baxter PE, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJ, Grant SG, McColl B, Komiyama N, Hardingham GE. Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of DAPK1. Elife. 6. PMID 28731405 DOI: 10.7554/Elife.17161 |
0.379 |
|
| 2017 |
Johnstone M, Vasistha N, Livesey M, Burr K, Whalley H, Clair DS, Blackwood D, Wyllie D, Lawrie S, Johnstone EC, McIntosh AM, Chandran S. Modelling a Genetic Risk for Schizophrenia in Human Induced Pluripotent Stem Cells (Ipscs): Phenotypic Differences in Patients with Mutations in Nde1 European Neuropsychopharmacology. 27: S509-S510. DOI: 10.1016/J.Euroneuro.2016.09.618 |
0.315 |
|
| 2016 |
Marwick K, Skehel P, Hardingham G, Wyllie D. Effect of a GRIN2A de novo mutation associated with epilepsy and intellectual disability on NMDA receptor currents and Mg(2+) block in cultured primary cortical neurons. Lancet (London, England). S65. PMID 26312887 DOI: 10.1016/S0140-6736(15)60380-4 |
0.477 |
|
| 2013 |
McKay S, Bengtson CP, Bading H, Wyllie DJ, Hardingham GE. Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure. Neuropharmacology. 74: 119-25. PMID 23402996 DOI: 10.1016/J.Neuropharm.2013.01.024 |
0.498 |
|
| 2013 |
Wyllie DJ, Livesey MR, Hardingham GE. Influence of GluN2 subunit identity on NMDA receptor function. Neuropharmacology. 74: 4-17. PMID 23376022 DOI: 10.1016/J.Neuropharm.2013.01.016 |
0.487 |
|
| 2012 |
Chia PW, Livesey MR, Slawin AM, van Mourik T, Wyllie DJ, O'Hagan D. 3-Fluoro-N-methyl-D-aspartic acid (3F-NMDA) stereoisomers as conformational probes for exploring agonist binding at NMDA receptors. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8813-9. PMID 22692769 DOI: 10.1002/Chem.201200071 |
0.364 |
|
| 2012 |
McMahon AC, Barnett MW, O'Leary TS, Stoney PN, Collins MO, Papadia S, Choudhary JS, Komiyama NH, Grant SG, Hardingham GE, Wyllie DJ, Kind PC. SynGAP isoforms exert opposing effects on synaptic strength. Nature Communications. 3: 900. PMID 22692543 DOI: 10.1038/Ncomms1900 |
0.341 |
|
| 2012 |
Edman S, McKay S, Macdonald LJ, Samadi M, Livesey MR, Hardingham GE, Wyllie DJ. TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner. Neuropharmacology. 63: 441-9. PMID 22579927 DOI: 10.1016/J.Neuropharm.2012.04.027 |
0.662 |
|
| 2012 |
Wyllie DJ, Traynelis SF. NMDA receptor permeation: a light in the tunnel. Nature Neuroscience. 15: 343-4. PMID 22362102 DOI: 10.1038/nn.3058 |
0.627 |
|
| 2012 |
McKay S, Griffiths NH, Butters PA, Thubron EB, Hardingham GE, Wyllie DJ. Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist. British Journal of Pharmacology. 166: 924-37. PMID 22022974 DOI: 10.1111/J.1476-5381.2011.01748.X |
0.516 |
|
| 2011 |
Otton HJ, Lawson McLean A, Pannozzo MA, Davies CH, Wyllie DJ. Quantification of the Mg2+-induced potency shift of amantadine and memantine voltage-dependent block in human recombinant GluN1/GluN2A NMDARs. Neuropharmacology. 60: 388-96. PMID 20955720 DOI: 10.1016/J.Neuropharm.2010.10.008 |
0.325 |
|
| 2010 |
Léveillé F, Papadia S, Fricker M, Bell KF, Soriano FX, Martel MA, Puddifoot C, Habel M, Wyllie DJ, Ikonomidou C, Tolkovsky AM, Hardingham GE. Suppression of the intrinsic apoptosis pathway by synaptic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2623-35. PMID 20164347 DOI: 10.1523/Jneurosci.5115-09.2010 |
0.346 |
|
| 2009 |
O'Leary T, Wyllie DJ. Single-channel properties of N-methyl-D-aspartate receptors containing chimaeric GluN2A/GluN2D subunits. Biochemical Society Transactions. 37: 1347-54. PMID 19909274 DOI: 10.1042/BST0371347 |
0.436 |
|
| 2009 |
Otton HJ, Janssen A, O'Leary T, Chen PE, Wyllie DJ. Inhibition of rat recombinant GluN1/GluN2A and GluN1/GluN2B NMDA receptors by ethanol at concentrations based on the US/UK drink-drive limit. European Journal of Pharmacology. 614: 14-21. PMID 19394328 DOI: 10.1016/j.ejphar.2009.04.034 |
0.405 |
|
| 2009 |
Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression. Channels (Austin, Tex.). 3: 12-5. PMID 19221512 DOI: 10.4161/Chan.3.1.7864 |
0.374 |
|
| 2009 |
Puddifoot CA, Chen PE, Schoepfer R, Wyllie DJ. Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes. British Journal of Pharmacology. 156: 509-18. PMID 19154422 DOI: 10.1111/j.1476-5381.2008.00040.x |
0.423 |
|
| 2009 |
Martel MA, Wyllie DJ, Hardingham GE. In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death. Neuroscience. 158: 334-43. PMID 18378405 DOI: 10.1016/J.Neuroscience.2008.01.080 |
0.497 |
|
| 2008 |
Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, ... ... Wyllie DJ, et al. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nature Neuroscience. 11: 476-87. PMID 18344994 DOI: 10.1038/Nn2071 |
0.311 |
|
| 2008 |
Wrighton DC, Baker EJ, Chen PE, Wyllie DJ. Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of Physiology. 586: 211-25. PMID 17962329 DOI: 10.1113/jphysiol.2007.143164 |
0.469 |
|
| 2008 |
Chen PE, Geballe MT, Katz E, Erreger K, Livesey MR, O'Toole KK, Le P, Lee CJ, Snyder JP, Traynelis SF, Wyllie DJ. Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of Physiology. 586: 227-45. PMID 17962328 DOI: 10.1113/Jphysiol.2007.143172 |
0.597 |
|
| 2007 |
Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF. Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. Molecular Pharmacology. 72: 907-20. PMID 17622578 DOI: 10.1124/Mol.107.037333 |
0.634 |
|
| 2007 |
Wyllie DJ, Chen PE. Taking the time to study competitive antagonism. British Journal of Pharmacology. 150: 541-51. PMID 17245371 DOI: 10.1038/sj.bjp.0706997 |
0.356 |
|
| 2006 |
Frizelle PA, Chen PE, Wyllie DJ. Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission. Molecular Pharmacology. 70: 1022-32. PMID 16778008 DOI: 10.1124/mol.106.024042 |
0.494 |
|
| 2006 |
Wyllie DJ, Johnston AR, Lipscombe D, Chen PE. Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit. The Journal of Physiology. 574: 477-89. PMID 16709630 DOI: 10.1113/jphysiol.2006.112193 |
0.523 |
|
| 2006 |
Baxter AW, Wyllie DJ. Phosphatidylinositol 3 kinase activation and AMPA receptor subunit trafficking underlie the potentiation of miniature EPSC amplitudes triggered by the activation of L-type calcium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5456-69. PMID 16707798 DOI: 10.1523/JNEUROSCI.4101-05.2006 |
0.367 |
|
| 2006 |
Chen PE, Wyllie DJ. Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors. British Journal of Pharmacology. 147: 839-53. PMID 16474411 DOI: 10.1038/sj.bjp.0706689 |
0.407 |
|
| 2005 |
Erreger K, Geballe MT, Dravid SM, Snyder JP, Wyllie DJ, Traynelis SF. Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7858-66. PMID 16120788 DOI: 10.1523/Jneurosci.1613-05.2005 |
0.677 |
|
| 2005 |
Vickers CA, Dickson KS, Wyllie DJ. Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neurones. The Journal of Physiology. 568: 803-13. PMID 16109729 DOI: 10.1113/Jphysiol.2005.092924 |
0.301 |
|
| 2005 |
Chen PE, Geballe MT, Stansfeld PJ, Johnston AR, Yuan H, Jacob AL, Snyder JP, Traynelis SF, Wyllie DJ. Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling. Molecular Pharmacology. 67: 1470-84. PMID 15703381 DOI: 10.1124/Mol.104.008185 |
0.647 |
|
| 2005 |
Erreger K, Dravid SM, Banke TG, Wyllie DJ, Traynelis SF. Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles. The Journal of Physiology. 563: 345-58. PMID 15649985 DOI: 10.1113/Jphysiol.2004.080028 |
0.682 |
|
| 2004 |
Erreger K, Chen PE, Wyllie DJ, Traynelis SF. Glutamate receptor gating. Critical Reviews in Neurobiology. 16: 187-224. PMID 15701057 DOI: 10.1615/Critrevneurobiol.V16.I3.10 |
0.645 |
|
| 2004 |
Chen PE, Johnston AR, Mok MH, Schoepfer R, Wyllie DJ. Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptors. The Journal of Physiology. 558: 45-58. PMID 15107472 DOI: 10.1113/jphysiol.2004.063800 |
0.537 |
|
| 2000 |
Anson LC, Schoepfer R, Colquhoun D, Wyllie DJ. Single-channel analysis of an NMDA receptor possessing a mutation in the region of the glutamate binding site. The Journal of Physiology. 527: 225-37. PMID 10970425 DOI: 10.1111/J.1469-7793.2000.00225.X |
0.482 |
|
| 2000 |
Misra C, Brickley SG, Wyllie DJ, Cull-Candy SG. Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells. The Journal of Physiology. 525: 299-305. PMID 10835034 DOI: 10.1111/j.1469-7793.2000.t01-1-00299.x |
0.712 |
|
| 1998 |
Wyllie DJ, Béhé P, Colquhoun D. Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. The Journal of Physiology. 510: 1-18. PMID 9625862 DOI: 10.1111/j.1469-7793.1998.001bz.x |
0.432 |
|
| 1998 |
Anson LC, Chen PE, Wyllie DJ, Colquhoun D, Schoepfer R. Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 581-9. PMID 9425000 DOI: 10.1523/Jneurosci.18-02-00581.1998 |
0.496 |
|
| 1997 |
Gibb AJ, Wyllie DJ. Single cell RT-PCR reaches out to the NMDA receptor. The Journal of Physiology. 499: 1. PMID 16993278 DOI: 10.1113/Jphysiol.1997.Sp021906 |
0.436 |
|
| 1996 |
Wyllie DJ, Béhé P, Nassar M, Schoepfer R, Colquhoun D. Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes. Proceedings. Biological Sciences / the Royal Society. 263: 1079-86. PMID 8805841 DOI: 10.1098/rspb.1996.0159 |
0.513 |
|
| 1995 |
Béhé P, Stern P, Wyllie DJ, Nassar M, Schoepfer R, Colquhoun D. Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors. Proceedings. Biological Sciences / the Royal Society. 262: 205-13. PMID 8524912 DOI: 10.1098/rspb.1995.0197 |
0.453 |
|
| 1994 |
Wyllie DJ, Nicoll RA. A role for protein kinases and phosphatases in the Ca(2+)-induced enhancement of hippocampal AMPA receptor-mediated synaptic responses. Neuron. 13: 635-43. PMID 7917294 DOI: 10.1016/0896-6273(94)90031-0 |
0.56 |
|
| 1994 |
Wyllie DJ, Cull-Candy SG. A comparison of non-NMDA receptor channels in type-2 astrocytes and granule cells from rat cerebellum. The Journal of Physiology. 475: 95-114. PMID 7514667 DOI: 10.1113/Jphysiol.1994.Sp020052 |
0.691 |
|
| 1994 |
Wyllie DJ, Manabe T, Nicoll RA. A rise in postsynaptic Ca2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons. Neuron. 12: 127-38. PMID 7507335 DOI: 10.1016/0896-6273(94)90158-9 |
0.666 |
|
| 1993 |
Manabe T, Wyllie DJ, Perkel DJ, Nicoll RA. Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus. Journal of Neurophysiology. 70: 1451-9. PMID 7904300 DOI: 10.1152/Jn.1993.70.4.1451 |
0.695 |
|
| 1993 |
Wyllie DJ, Traynelis SF, Cull-Candy SG. Evidence for more than one type of non-NMDA receptor in outside-out patches from cerebellar granule cells of the rat. The Journal of Physiology. 463: 193-226. PMID 7504104 DOI: 10.1113/jphysiol.1993.sp019591 |
0.716 |
|
| 1991 |
Cull-Candy SG, Wyllie DJ. Glutamate-receptor channels in mammalian glial cells. Annals of the New York Academy of Sciences. 633: 458-74. PMID 1686383 DOI: 10.1111/j.1749-6632.1991.tb15636.x |
0.677 |
|
| 1991 |
Wyllie DJ, Mathie A, Symonds CJ, Cull-Candy SG. Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures. The Journal of Physiology. 432: 235-58. PMID 1653320 DOI: 10.1113/Jphysiol.1991.Sp018383 |
0.661 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2010 |
Clayton EL, Sue N, Smillie KJ, O'Leary T, Bache N, Cheung G, Cole AR, Wyllie DJ, Sutherland C, Robinson PJ, Cousin MA. Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles. Nature Neuroscience. 13: 845-51. PMID 20526333 DOI: 10.1038/Nn.2571 |
0.298 |
|
| 2012 |
Puddifoot C, Martel MA, Soriano FX, Camacho A, Vidal-Puig A, Wyllie DJ, Hardingham GE. PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6995-7000. PMID 22593067 DOI: 10.1523/Jneurosci.6407-11.2012 |
0.297 |
|
| 2010 |
Hardingham GE, Patani R, Baxter P, Wyllie DJ, Chandran S. Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration. Molecular Neurobiology. 42: 97-102. PMID 20431962 DOI: 10.1007/S12035-010-8136-2 |
0.295 |
|
| 2010 |
O'Leary T, van Rossum MC, Wyllie DJ. Homeostasis of intrinsic excitability in hippocampal neurones: dynamics and mechanism of the response to chronic depolarization. The Journal of Physiology. 588: 157-70. PMID 19917565 DOI: 10.1113/Jphysiol.2009.181024 |
0.293 |
|
| 2012 |
Martel MA, Ryan TJ, Bell KF, Fowler JH, McMahon A, Al-Mubarak B, Komiyama NH, Horsburgh K, Kind PC, Grant SG, Wyllie DJ, Hardingham GE. The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults. Neuron. 74: 543-56. PMID 22578505 DOI: 10.1016/J.Neuron.2012.03.021 |
0.293 |
|
| 2016 |
Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, ... ... Wyllie DJ, et al. Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons. Elife. 5. PMID 27692071 DOI: 10.7554/Elife.20337 |
0.282 |
|
| 2008 |
Soriano FX, Martel MA, Papadia S, Vaslin A, Baxter P, Rickman C, Forder J, Tymianski M, Duncan R, Aarts M, Clarke P, Wyllie DJ, Hardingham GE. Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10696-710. PMID 18923045 DOI: 10.1523/Jneurosci.1207-08.2008 |
0.27 |
|
| 2014 |
James OT, Livesey MR, Qiu J, Dando O, Bilican B, Haghi G, Rajan R, Burr K, Hardingham GE, Chandran S, Kind PC, Wyllie DJ. Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones. The Journal of Physiology. 592: 4353-63. PMID 25172951 DOI: 10.1113/Jphysiol.2014.278994 |
0.26 |
|
| 2016 |
Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, ... ... Wyllie DJ, et al. Author response: Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons Elife. DOI: 10.7554/Elife.20337.021 |
0.255 |
|
| 2015 |
Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SG, Bear MF, Nägerl UV, Kind PC, Wyllie DJ. Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15073-81. PMID 26558778 DOI: 10.1523/Jneurosci.1087-15.2015 |
0.238 |
|
| 2014 |
Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJ. Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4070-5. PMID 24623784 DOI: 10.1523/Jneurosci.5410-13.2014 |
0.234 |
|
| 2013 |
Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE. Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals. Nature Communications. 4: 2034. PMID 23774321 DOI: 10.1038/Ncomms3034 |
0.231 |
|
| 2017 |
Booker SA, Campbell GR, Mysiak KS, Brophy PJ, Kind PC, Mahad DJ, Wyllie DJ. Loss of protoheme IX farnesyltransferase in mature dentate granule cells impairs short term plasticity onto CA3 pyramidal cells. The Journal of Physiology. PMID 28083896 DOI: 10.1113/Jp273581 |
0.22 |
|
| 2016 |
Perkins EM, Suminaite D, Clarkson YL, Lee SK, Lyndon AR, Rothstein JD, Wyllie DJ, Tanaka K, Jackson M. Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST. Human Molecular Genetics. PMID 27530255 DOI: 10.1093/hmg/ddw274 |
0.211 |
|
| 2016 |
Livesey MR, Magnani D, Cleary EM, Vasistha NA, James OT, Selvaraj BT, Burr K, Story D, Shaw CE, Kind PC, Hardingham GE, Wyllie DJ, Chandran S. Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes. Stem Cells (Dayton, Ohio). PMID 26763608 DOI: 10.1002/Stem.2273 |
0.21 |
|
| 2016 |
Perkins EM, Suminaite D, Clarkson YL, Lee SK, Lyndon AR, Rothstein JD, Wyllie DJ, Tanaka K, Jackson M. Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST. Human Molecular Genetics. 25: 4448-4461. PMID 28173092 DOI: 10.1093/hmg/ddw274 |
0.21 |
|
| 1991 |
Lightstone EB, Wyllie D, Marvel J. In the mouse the maturation stage of the peripheral CD4+CD45RA+ subset is different from that of the CD8+CD45RA+ subset European Journal of Immunology. 21: 2161-2165. PMID 1679713 DOI: 10.1002/Eji.1830210926 |
0.209 |
|
| 2007 |
Vickers CA, Wyllie DJ. Late-phase, protein synthesis-dependent long-term potentiation in hippocampal CA1 pyramidal neurones with destabilized microtubule networks. British Journal of Pharmacology. 151: 1071-7. PMID 17549044 DOI: 10.1038/sj.bjp.0707314 |
0.204 |
|
| 2009 |
Otton HJ, Janssen A, Wyllie DJ. Inhibition of recombinant GluN1/GluN2A and GluN1/GluN2B N-methyl-D-aspartate receptors by single malt whiskies. Biochemical Society Transactions. 37: 1423-5. PMID 19909290 DOI: 10.1042/BST0371423 |
0.182 |
|
| 2014 |
Bilican B, Livesey MR, Haghi G, Qiu J, Burr K, Siller R, Hardingham GE, Wyllie DJ, Chandran S. Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells. Plos One. 9: e85932. PMID 24465796 DOI: 10.1371/Journal.Pone.0085932 |
0.158 |
|
| 2014 |
Sharma R, Livesey MR, Wyllie DJ, Proudfoot C, Whitelaw CB, Hay DC, Donadeu FX. Generation of functional neurons from feeder-free, keratinocyte-derived equine induced pluripotent stem cells. Stem Cells and Development. 23: 1524-34. PMID 24548115 DOI: 10.1089/scd.2013.0565 |
0.155 |
|
| 2015 |
Till SM, Asiminas A, Jackson AD, Katsanevaki D, Barnes SA, Osterweil EK, Bear MF, Chattarji S, Wood ER, Wyllie DJ, Kind PC. Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS. Human Molecular Genetics. PMID 26243794 DOI: 10.1093/Hmg/Ddv299 |
0.147 |
|
| 2012 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8. PMID 22451909 DOI: 10.1073/Pnas.1202922109 |
0.147 |
|
| 2006 |
Gillingwater TH, Wishart TM, Chen PE, Haley JE, Robertson K, MacDonald SH, Middleton S, Wawrowski K, Shipston MJ, Melmed S, Wyllie DJ, Skehel PA, Coleman MP, Ribchester RR. The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Human Molecular Genetics. 15: 625-35. PMID 16403805 DOI: 10.1093/Hmg/Ddi478 |
0.145 |
|
| 2010 |
Perkins EM, Clarkson YL, Sabatier N, Longhurst DM, Millward CP, Jack J, Toraiwa J, Watanabe M, Rothstein JD, Lyndon AR, Wyllie DJ, Dutia MB, Jackson M. Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4857-67. PMID 20371805 DOI: 10.1523/JNEUROSCI.6065-09.2010 |
0.143 |
|
| 2008 |
O'Leary T, Wyllie DJ. The ups and downs of synaptic plasticity: influences on this particular 'market'. The Journal of Physiology. 586: 5839-40. PMID 19074816 DOI: 10.1113/jphysiol.2008.165720 |
0.14 |
|
| 2012 |
Patani R, Lewis PA, Trabzuni D, Puddifoot CA, Wyllie DJ, Walker R, Smith C, Hardingham GE, Weale M, Hardy J, Chandran S, Ryten M. Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis. Journal of Neurochemistry. 122: 738-51. PMID 22681703 DOI: 10.1111/J.1471-4159.2012.07825.X |
0.132 |
|
| 2015 |
Livesey MR, Magnani D, Hardingham GE, Chandran S, Wyllie DJ. Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells. The Journal of Physiology. PMID 26608229 DOI: 10.1113/Jp270660 |
0.129 |
|
| 2008 |
Wilbrey AL, Haley JE, Wishart TM, Conforti L, Morreale G, Beirowski B, Babetto E, Adalbert R, Gillingwater TH, Smith T, Wyllie DJ, Ribchester RR, Coleman MP. VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S). Molecular and Cellular Neurosciences. 38: 325-40. PMID 18468455 DOI: 10.1016/J.Mcn.2008.03.004 |
0.121 |
|
| 2015 |
Bell KF, Al-Mubarak B, Martel MA, McKay S, Wheelan N, Hasel P, Márkus NM, Baxter P, Deighton RF, Serio A, Bilican B, Chowdhry S, Meakin PJ, Ashford ML, Wyllie DJ, et al. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nature Communications. 6: 7066. PMID 25967870 DOI: 10.1038/Ncomms8066 |
0.117 |
|
| 2011 |
Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJ, Compston DA, Pedersen RA, Gillingwater TH, Hardingham GE, Allen ND, Chandran S. Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state. Nature Communications. 2: 214. PMID 21364553 DOI: 10.1038/Ncomms1216 |
0.116 |
|
| 2017 |
Currie SP, Luz LL, Booker SA, Wyllie DJ, Kind PC, Daw MI. Reduced local input to fast-spiking interneurons in the somatosensory cortex in the GABAA γ2 R43Q mouse model of absence epilepsy. Epilepsia. PMID 28195311 DOI: 10.1111/Epi.13693 |
0.115 |
|
| 2003 |
Lawrie A, Brisken AF, Francis SE, Wyllie D, Kiss-Toth E, Qwarnstrom EE, Dower SK, Crossman DC, Newman CM. Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals Ultrasound in Medicine and Biology. 29: 1453-1461. PMID 14597342 DOI: 10.1016/S0301-5629(03)01032-9 |
0.112 |
|
| 2016 |
Rzechorzek NM, Connick P, Livesey MR, Borooah S, Patani R, Burr K, Story D, Wyllie DJ, Hardingham GE, Chandran S. Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition. Ebiomedicine. 3: 141-54. PMID 26870825 DOI: 10.1016/J.Ebiom.2015.12.010 |
0.109 |
|
| 2011 |
O'Leary T, Wyllie DJ. Neuronal homeostasis: time for a change? The Journal of Physiology. 589: 4811-26. PMID 21825033 DOI: 10.1113/Jphysiol.2011.210179 |
0.096 |
|
| 2022 |
Marsay L, Dold C, Paterson GK, Yamaguchi Y, Derrick JP, Chan H, Feavers IM, Maiden MCJ, Wyllie D, Hill AV, Pollard AJ, Rollier CS. Viral vectors expressing group B meningococcal outer membrane proteins induce strong antibody responses but fail to induce functional bactericidal activity. The Journal of Infection. PMID 35245584 DOI: 10.1016/j.jinf.2022.02.032 |
0.094 |
|
| 2017 |
Zanato C, Pelagalli A, Marwick KF, Piras M, Dall'Angelo S, Spinaci A, Pertwee RG, Wyllie DJ, Hardingham GE, Zanda M. Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers. Organic & Biomolecular Chemistry. PMID 28210722 DOI: 10.1039/C6Ob02796B |
0.094 |
|
| 2009 |
Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S. Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity. Plos One. 4: e7327. PMID 19806200 DOI: 10.1371/Journal.Pone.0007327 |
0.091 |
|
| 2013 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, et al. Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2. PMID 23740897 DOI: 10.1126/Scitranslmed.3005065 |
0.087 |
|
| 2020 |
Rollier CS, Spencer AJ, Sogaard KC, Honeycutt J, Furze J, Bregu M, Gilbert SC, Wyllie D, Hill AVS. Modification of Adenovirus vaccine vector-induced immune responses by expression of a signalling molecule. Scientific Reports. 10: 5716. PMID 32235848 DOI: 10.1038/s41598-020-61730-8 |
0.083 |
|
| 2021 |
Helekal D, Ledda A, Volz E, Wyllie D, Didelot X. Bayesian inference of clonal expansions in a dated phylogeny. Systematic Biology. PMID 34893904 DOI: 10.1093/sysbio/syab095 |
0.076 |
|
| 2020 |
Stoesser N, Phan HTT, Seale AC, Aiken Z, Thomas S, Smith M, Wyllie D, George R, Sebra R, Mathers AJ, Vaughan A, Peto TEA, Ellington MJ, Hopkins KL, Crook DW, et al. Genomic epidemiology of complex, multi-species, plasmid-borne carbapenemase in Enterobacterales in the UK, 2009-2014. Antimicrobial Agents and Chemotherapy. PMID 32094139 DOI: 10.1128/Aac.02244-19 |
0.075 |
|
| 2022 |
Wilkie M, Tanner R, Wright D, Lopez Ramon R, Beglov J, Riste M, Marshall JL, Harris SA, Bettencourt PJG, Hamidi A, van Diemen PM, Moss P, Satti I, Wyllie D, McShane H. Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study. Scientific Reports. 12: 7808. PMID 35552463 DOI: 10.1038/s41598-022-11748-x |
0.072 |
|
| 2023 |
Dold C, Marsay L, Wang N, Silva-Reyes L, Clutterbuck E, Paterson GK, Sharkey K, Wyllie D, Beernink PT, Hill AV, Pollard AJ, Rollier CS. An adenoviral-vectored vaccine confers seroprotection against capsular group B meningococcal disease. Science Translational Medicine. 15: eade3901. PMID 37343082 DOI: 10.1126/scitranslmed.ade3901 |
0.071 |
|
| 2016 |
Daniels-Treffandier H, de Nie K, Marsay L, Dold C, Sadarangani M, Reyes-Sandoval A, Langford PR, Wyllie D, Hill F, Pollard AJ, Rollier CS. Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles. Plos One. 11: e0148840. PMID 26871712 DOI: 10.1371/journal.pone.0148840 |
0.067 |
|
| 2019 |
Young BC, Earle SG, Soeng S, Sar P, Kumar V, Hor S, Sar V, Bousfield R, Sanderson ND, Barker L, Stoesser N, Emary KR, Parry CM, Nickerson EK, Turner P, ... ... Wyllie DJ, et al. Panton-Valentine leucocidin is the key determinant of pyomyositis in a bacterial GWAS. Elife. 8. PMID 30794157 DOI: 10.7554/eLife.42486 |
0.061 |
|
| 2012 |
Eyre DW, Walker AS, Wyllie D, Dingle KE, Griffiths D, Finney J, O'Connor L, Vaughan A, Crook DW, Wilcox MH, Peto TE. Predictors of first recurrence of Clostridium difficile infection: implications for initial management. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 55: S77-87. PMID 22752869 DOI: 10.1093/cid/cis356 |
0.056 |
|
| 2022 |
Findlater L, Trickey A, Jones HE, Trindall A, Taylor-Phillips S, Mulchandani R, Oliver I, Wyllie D. Association of Results of Four Lateral Flow Antibody Tests with Subsequent SARS-CoV-2 Infection. Microbiology Spectrum. e0246822. PMID 36135374 DOI: 10.1128/spectrum.02468-22 |
0.053 |
|
| 2022 |
Volk D, Yang-Turner F, Didelot X, Crook DW, Wyllie D. Catwalk: identifying closely related sequences in large microbial sequence databases. Microbial Genomics. 8. PMID 35771206 DOI: 10.1099/mgen.0.000850 |
0.052 |
|
| 2022 |
Walker TM, Choisy M, Dedicoat M, Drennan PG, Wyllie D, Yang-Turner F, Crook DW, Robinson ER, Walker AS, Smith EG, Peto TEA. transmission in Birmingham, UK, 2009-19: An observational study. The Lancet Regional Health. Europe. 17: 100361. PMID 35345560 DOI: 10.1016/j.lanepe.2022.100361 |
0.052 |
|
| 2024 |
Carson J, Keeling M, Wyllie D, Ribeca P, Didelot X. Inference of Infectious Disease Transmission through a Relaxed Bottleneck Using Multiple Genomes Per Host. Molecular Biology and Evolution. 41. PMID 38168711 DOI: 10.1093/molbev/msad288 |
0.049 |
|
| 2014 |
Matthews PC, Chue AL, Wyllie D, Barnett A, Isinkaye T, Jefferies L, Lovering A, Scarborough M. Increased teicoplanin doses are associated with improved serum levels but not drug toxicity. The Journal of Infection. 68: 43-9. PMID 24012820 DOI: 10.1016/j.jinf.2013.08.018 |
0.046 |
|
| 2015 |
Pankhurst LJ, Del Ojo Elias C, Votintseva AA, Walker TM, Cole K, Davies J, Fermont JM, Gascoyne-Binzi DM, Kohl TA, Kong C, Lemaitre N, Niemann S, Paul J, Rogers TR, Roycroft E, ... ... Wyllie D, et al. Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study. The Lancet. Respiratory Medicine. PMID 26669893 DOI: 10.1016/S2213-2600(15)00466-X |
0.044 |
|
| 2013 |
Wijetunge LS, Chattarji S, Wyllie DJ, Kind PC. Fragile X syndrome: from targets to treatments. Neuropharmacology. 68: 83-96. PMID 23257237 DOI: 10.1016/j.neuropharm.2012.11.028 |
0.041 |
|
| 2016 |
Stoesser N, Sheppard AE, Pankhurst L, De Maio N, Moore CE, Sebra R, Turner P, Anson LW, Kasarskis A, Batty EM, Kos V, Wilson DJ, Phetsouvanh R, Wyllie D, Sokurenko E, et al. Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131. Mbio. 7. PMID 27006459 DOI: 10.1128/Mbio.02162-15 |
0.04 |
|
| 2022 |
Wyllie D, Do T, Myers R, Nikolayevskyy V, Crook D, Peto T, Alexander E, Robinson E, Walker AS, Campbell C, Smith EG. M. tuberculosis microvariation is common and is associated with transmission: analysis of three years prospective universal sequencing in England. The Journal of Infection. PMID 35595102 DOI: 10.1016/j.jinf.2022.05.011 |
0.039 |
|
| 2008 |
Walker S, Peto TE, O'Connor L, Crook DW, Wyllie D. Are there better methods of monitoring MRSA control than bacteraemia surveillance? An observational database study. Plos One. 3: e2378. PMID 18545686 DOI: 10.1371/journal.pone.0002378 |
0.033 |
|
| 2008 |
Wyllie DJ. 2B or 2B and 2D? - that is the question. The Journal of Physiology. 586: 693. PMID 18245207 DOI: 10.1113/jphysiol.2007.148924 |
0.033 |
|
| 2021 |
Jones HE, Mulchandani R, Taylor-Phillips S, Ades AE, Shute J, Perry KR, Chandra NL, Brooks T, Charlett A, Hickman M, Oliver I, Kaptoge S, Danesh J, Di Angelantonio E, Wyllie D, et al. Accuracy of four lateral flow immunoassays for anti SARS-CoV-2 antibodies: a head-to-head comparative study. Ebiomedicine. 68: 103414. PMID 34098341 DOI: 10.1016/j.ebiom.2021.103414 |
0.029 |
|
| 2011 |
Wyllie D, Paul J, Crook D. Waves of trouble: MRSA strain dynamics and assessment of the impact of infection control. The Journal of Antimicrobial Chemotherapy. 66: 2685-8. PMID 21948966 DOI: 10.1093/jac/dkr392 |
0.029 |
|
| 2016 |
Quan TP, Fawcett NJ, Wrightson JM, Finney J, Wyllie D, Jeffery K, Jones N, Shine B, Clarke L, Crook D, Walker AS, Peto TE. Increasing burden of community-acquired pneumonia leading to hospitalisation, 1998-2014. Thorax. 71: 535-42. PMID 26888780 DOI: 10.1136/thoraxjnl-2015-207688 |
0.023 |
|
| 2021 |
Mulchandani R, Taylor-Philips S, Jones HE, Ades AE, Borrow R, Linley E, Kirwan PD, Stewart R, Moore P, Boyes J, Hormis A, Todd N, Colda A, Reckless I, Brooks T, ... ... Wyllie D, et al. Association between self-reported signs and symptoms and SARS-CoV-2 antibody detection in UK key workers. The Journal of Infection. PMID 33775704 DOI: 10.1016/j.jinf.2021.03.019 |
0.021 |
|
| 2021 |
Mulchandani R, Brown B, Brooks T, Semper A, Machin N, Linley E, Borrow R, Wyllie D. Use of dried blood spot samples for SARS-CoV-2 antibody detection using the Roche Elecsys ® high throughput immunoassay. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 136: 104739. PMID 33588354 DOI: 10.1016/j.jcv.2021.104739 |
0.02 |
|
| 2022 |
Blakey E, Reeve L, Verlander NQ, Edwards D, Wyllie D, Reacher M. Social risk factors for SARS-CoV-2 acquisition in University students: cross sectional survey. Epidemiology and Infection. 1-23. PMID 36328978 DOI: 10.1017/S0950268822001698 |
0.016 |
|
| 2018 |
Allix-Béguec C, Arandjelovic I, Bi L, Beckert P, Bonnet M, Bradley P, Cabibbe AM, Cancino-Muñoz I, Caulfield MJ, Chaiprasert A, Cirillo DM, Clifton DA, Comas I, Crook DW, ... ... Wyllie D, et al. Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing. The New England Journal of Medicine. 379: 1403-1415. PMID 30280646 DOI: 10.1056/Nejmoa1800474 |
0.015 |
|
| 2021 |
Farooq HZ, Cirillo DM, Hillemann D, Wyllie D, van der Werf MJ, Ködmön C, Nikolayevskyy V. Limited Capability for Testing Mycobacterium tuberculosis for Susceptibility to New Drugs. Emerging Infectious Diseases. 27: 985-987. PMID 33622487 DOI: 10.3201/eid2703.204418 |
0.014 |
|
| 2021 |
Budgell EP, Davies T, Donker T, Hopkins S, Wyllie D, Peto TEA, Gill M, Llewelyn MJ, Walker AS. Impact of hospital antibiotic use on patient-level risk of death among 36,124,372 acute and medical admissions in England. The Journal of Infection. PMID 34963640 DOI: 10.1016/j.jinf.2021.12.029 |
0.014 |
|
| 2008 |
Miller R, Esmail H, Peto T, Walker S, Crook D, Wyllie D. Is MRSA admission bacteraemia community-acquired? A case control study. The Journal of Infection. 56: 163-70. PMID 18242713 DOI: 10.1016/j.jinf.2007.12.004 |
0.011 |
|
| 2008 |
Walker AS, Spiegelhalter D, Crook DW, Wyllie D, Morris J, Peto TE. Fairness of financial penalties to improve control of Clostridium difficile. Bmj (Clinical Research Ed.). 337: a2097. PMID 19022838 DOI: 10.1136/bmj.a2097 |
0.01 |
|
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