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Kyle M. Brown, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
evolutionary biology, molecular genetics
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, ... Brown KM, et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Research. PMID 26603897 DOI: 10.1158/0008-5472.Can-15-0885  0.356
2015 Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown KM, et al. Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell Reports. 11: 1458-73. PMID 26027934 DOI: 10.1016/J.Celrep.2015.04.049  0.385
2011 Costanzo MS, Brown KM, Hartl DL. Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum. Plos One. 6: e19636. PMID 21625425 DOI: 10.1371/Journal.Pone.0019636  0.605
2010 Brown KM, Costanzo MS, Xu W, Roy S, Lozovsky ER, Hartl DL. Compensatory mutations restore fitness during the evolution of dihydrofolate reductase. Molecular Biology and Evolution. 27: 2682-90. PMID 20576759 DOI: 10.1093/Molbev/Msq160  0.649
2009 Brown KM, Depristo MA, Weinreich DM, Hartl DL. Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways. Molecular Biology and Evolution. 26: 2455-62. PMID 19602543 DOI: 10.1093/Molbev/Msp151  0.655
2009 Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. 106: 12025-30. PMID 19587242 DOI: 10.1073/Pnas.0905922106  0.507
2008 Brown KM, Landry CR, Hartl DL, Cavalieri D. Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae. Molecular Ecology. 17: 2985-97. PMID 18422925 DOI: 10.1111/J.1365-294X.2008.03765.X  0.605
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