Year |
Citation |
Score |
2022 |
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, ... ... Patricelli MP, et al. Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology. PMID 36180594 DOI: 10.1038/s41589-022-01181-6 |
0.638 |
|
2022 |
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AP, Rodriguez JL, Rodiles S, Masuda K, ... ... Patricelli MP, et al. Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology. PMID 36097295 DOI: 10.1038/s41589-022-01098-0 |
0.67 |
|
2020 |
Baltgalvis K, Kikuchi S, Symons K, Klebba J, Luukkonen L, Naro Y, Walsh C, Chang J, Chapman C, Tabatabaei A, Nordin B, Eissler C, Chick J, Whitby L, Brannon J, ... ... Patricelli M, et al. Abstract 6411: Discovery of covalent ligands to novel E3 ligases enables bispecific degraders with highly differentiated protein degradation across a broad range of targets Cancer Research. 80: 6411-6411. DOI: 10.1158/1538-7445.Am2020-6411 |
0.325 |
|
2018 |
Janes MR, Zhang J, Li LS, Hansen R, Peters U, Guo X, Chen Y, Babbar A, Firdaus SJ, Darjania L, Feng J, Chen JH, Li S, Li S, Long YO, ... ... Patricelli MP, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 172: 578-589.e17. PMID 29373830 DOI: 10.1016/J.Cell.2018.01.006 |
0.389 |
|
2017 |
Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 12: e0172649. PMID 28199383 DOI: 10.1371/Journal.Pone.0172649 |
0.327 |
|
2016 |
Matthews JM, Bhatt S, Patricelli MP, Nomanbhoy TK, Jiang X, Natkunam Y, Gentles AJ, Martinez E, Zhu D, Chapman JR, Cortizas E, Shyam R, Chinichian S, Advani R, Tan L, et al. Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma. Blood. PMID 27151888 DOI: 10.1182/Blood-2016-02-696856 |
0.336 |
|
2016 |
Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 11: e0152934. PMID 27031502 DOI: 10.1371/Journal.Pone.0152934 |
0.377 |
|
2016 |
Patricelli MP, Janes MR, Li LS, Hansen R, Peters U, Kessler LV, Chen Y, Kucharski JM, Feng J, Ely T, Chen JH, Firdaus SJ, Babbar A, Ren P, Liu Y. Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State. Cancer Discovery. PMID 26739882 DOI: 10.1158/2159-8290.Cd-15-1105 |
0.337 |
|
2016 |
Kessler L, Chen J, Guo X, Hensen R, Patricelli M, Li S, Thach C, Darjania L, Li S, Wu T, Hu-Lowe D, Yao Y, Zarieh A, Janes M, Ely T, et al. KO-947, a potent and selective ERK inhibitor with slow dissociation kinetics European Journal of Cancer. 69: S126. DOI: 10.1016/S0959-8049(16)32974-4 |
0.36 |
|
2016 |
Kessler L, Wu T, Grembecka J, Cierpicki T, Purohit T, Miao H, Kempinska K, Ely T, Hensen R, Li S, Patricelli M, Kucharski J, Zhang J, Yao Y, Yu K, et al. Discovery of novel menin-MLL small molecule inhibitors that display high potency and selectivity in vitro and in vivo European Journal of Cancer. 69. DOI: 10.1016/S0959-8049(16)32859-3 |
0.335 |
|
2015 |
Nonami A, Sattler M, Weisberg E, Liu Q, Zhang J, Patricelli MP, Christie AL, Saur AM, Kohl NE, Kung AL, Yoon H, Sim T, Gray NS, Griffin JD. Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach. Blood. 125: 3133-43. PMID 25833960 DOI: 10.1182/Blood-2014-12-615906 |
0.395 |
|
2015 |
Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, et al. Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). Journal of Medicinal Chemistry. 58: 183-96. PMID 25075558 DOI: 10.1021/Jm500480K |
0.376 |
|
2014 |
Okerberg ES, Brown HE, Minimo L, Alemayehu S, Rosenblum J, Patricelli M, Nomanbhoy T, Kozarich JW. Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe. Journal of the American Chemical Society. 136: 4664-9. PMID 24601623 DOI: 10.1021/Ja4129907 |
0.422 |
|
2014 |
Atkins C, Evans CW, Nordin B, Patricelli MP, Reynolds R, Wennerberg K, Noah JW. Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza. Journal of Biomolecular Screening. 19: 936-946. PMID 24464431 DOI: 10.1177/1087057113518068 |
0.308 |
|
2013 |
Villamor JG, Kaschani F, Colby T, Oeljeklaus J, Zhao D, Kaiser M, Patricelli MP, van der Hoorn RA. Profiling protein kinases and other ATP binding proteins in Arabidopsis using Acyl-ATP probes. Molecular & Cellular Proteomics : McP. 12: 2481-96. PMID 23722185 DOI: 10.1074/Mcp.M112.026278 |
0.385 |
|
2013 |
Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, et al. Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR. Cancer Research. 73: 2574-86. PMID 23436801 DOI: 10.1158/0008-5472.Can-12-1702 |
0.42 |
|
2013 |
Matthews JM, Tan L, Bhatt S, Patricelli M, Nomanbhoy T, Zhang J, Jiang X, Natkunam Y, Choi HG, Gentles AJ, Martinez E, Zhu D, Chapman JR, Shyam RM, Chinichian S, et al. Germinal Center Kinase Regulates The Proliferation and Survival Of Diffuse Large B-Cell Lymphoma Blood. 122: 643-643. DOI: 10.1182/Blood.V122.21.643.643 |
0.369 |
|
2012 |
Choi HG, Zhang J, Deng X, Hatcher JM, Patricelli MP, Zhao Z, Alessi DR, Gray NS. Brain Penetrant LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 3: 658-662. PMID 23066449 DOI: 10.1021/Ml300123A |
0.356 |
|
2012 |
Vetter ML, Rodgers MA, Patricelli MP, Yang PL. Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection. Acs Chemical Biology. 7: 2019-26. PMID 22999307 DOI: 10.1021/Cb300420Z |
0.31 |
|
2012 |
Dix MM, Simon GM, Wang C, Okerberg E, Patricelli MP, Cravatt BF. Functional interplay between caspase cleavage and phosphorylation sculpts the apoptotic proteome. Cell. 150: 426-40. PMID 22817901 DOI: 10.1016/J.Cell.2012.05.040 |
0.705 |
|
2012 |
Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, et al. Discovery of potent and selective covalent inhibitors of JNK. Chemistry & Biology. 19: 140-54. PMID 22284361 DOI: 10.1016/J.Chembiol.2011.11.010 |
0.452 |
|
2012 |
Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, et al. Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics. The Journal of Biological Chemistry. 287: 9742-52. PMID 22223645 DOI: 10.1074/Jbc.M111.304485 |
0.45 |
|
2011 |
Patricelli MP, Nomanbhoy TK, Wu J, Brown H, Zhou D, Zhang J, Jagannathan S, Aban A, Okerberg E, Herring C, Nordin B, Weissig H, Yang Q, Lee JD, Gray NS, et al. In situ kinase profiling reveals functionally relevant properties of native kinases. Chemistry & Biology. 18: 699-710. PMID 21700206 DOI: 10.1016/J.Chembiol.2011.04.011 |
0.448 |
|
2011 |
Chou TF, Brown SJ, Minond D, Nordin BE, Li K, Jones AC, Chase P, Porubsky PR, Stoltz BM, Schoenen FJ, Patricelli MP, Hodder P, Rosen H, Deshaies RJ. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 4834-9. PMID 21383145 DOI: 10.1073/Pnas.1015312108 |
0.377 |
|
2011 |
Deng X, Dzamko N, Prescott A, Davies P, Liu Q, Yang Q, Lee JD, Patricelli MP, Nomanbhoy TK, Alessi DR, Gray NS. Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2. Nature Chemical Biology. 7: 203-5. PMID 21378983 DOI: 10.1038/Nchembio.538 |
0.344 |
|
2010 |
Yang Q, Deng X, Lu B, Cameron M, Fearns C, Patricelli MP, Yates JR, Gray NS, Lee JD. Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein. Cancer Cell. 18: 258-67. PMID 20832753 DOI: 10.1016/J.Ccr.2010.08.008 |
0.338 |
|
2010 |
Matthews JM, Natkunam Y, Srinivasan S, Patricelli M, Nomanbhoy T, Cerchietti L, Melnick AM, Lossos IS. STAT3, Constitutively Activated In ABC-Like DLBCL, Regulates Expression of the Prognostic Factor Cyclin D2 Blood. 116: 705-705. DOI: 10.1182/Blood.V116.21.705.705 |
0.315 |
|
2010 |
Patricelli MP, Nomanbhoy TK, Kozarich JW, Gray NS, Zhang J, Wu J. Abstract 5578: Quantitative kinase inhibitor profiling in native cell and tissue extracts Cancer Research. 70: 5578-5578. DOI: 10.1158/1538-7445.Am10-5578 |
0.417 |
|
2010 |
Nomanbhoy TK, Ng DM, Patricelli MP. Abstract 5577: Global analysis of protein kinase activity during hematopoietic differentiation Cancer Research. 70: 5577-5577. DOI: 10.1158/1538-7445.Am10-5577 |
0.385 |
|
2008 |
Liu Y, Wu J, Weissig H, Betancort JM, Gai WZ, Leventhal PS, Patricelli MP, Samii B, Szardenings AK, Shreder KR, Kozarich JW. Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta. Bioorganic & Medicinal Chemistry Letters. 18: 5955-8. PMID 18774710 DOI: 10.1016/J.Bmcl.2008.08.045 |
0.334 |
|
2007 |
Patricelli MP, Szardenings AK, Liyanage M, Nomanbhoy TK, Wu M, Weissig H, Aban A, Chun D, Tanner S, Kozarich JW. Functional interrogation of the kinome using nucleotide acyl phosphates. Biochemistry. 46: 350-8. PMID 17209545 DOI: 10.1021/Bi062142X |
0.485 |
|
2005 |
Okerberg ES, Wu J, Zhang B, Samii B, Blackford K, Winn DT, Shreder KR, Burbaum JJ, Patricelli MP. High-resolution functional proteomics by active-site peptide profiling. Proceedings of the National Academy of Sciences of the United States of America. 102: 4996-5001. PMID 15795380 DOI: 10.1073/Pnas.0501205102 |
0.396 |
|
2005 |
Jessani N, Young JA, Diaz SL, Patricelli MP, Varki A, Cravatt BF. Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling. Angewandte Chemie (International Ed. in English). 44: 2400-3. PMID 15765498 DOI: 10.1002/Anie.200463098 |
0.711 |
|
2004 |
Adam GC, Burbaum J, Kozarich JW, Patricelli MP, Cravatt BF. Mapping enzyme active sites in complex proteomes. Journal of the American Chemical Society. 126: 1363-8. PMID 14759193 DOI: 10.1021/Ja038441G |
0.718 |
|
2002 |
Patricelli MP. Activity-based probes for functional proteomics. Briefings in Functional Genomics & Proteomics. 1: 151-8. PMID 15239901 DOI: 10.1093/Bfgp/1.2.151 |
0.382 |
|
2001 |
Patricelli MP, Giang DK, Stamp LM, Burbaum JJ. Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes. Proteomics. 1: 1067-71. PMID 11990500 DOI: 10.1002/1615-9861(200109)1:9<1067::Aid-Prot1067>3.0.Co;2-4 |
0.385 |
|
2001 |
Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 98: 9371-6. PMID 11470906 DOI: 10.1073/Pnas.161191698 |
0.612 |
|
2001 |
Patricelli MP, Cravatt BF. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry. 40: 6107-15. PMID 11352748 DOI: 10.1021/Bi002578R |
0.509 |
|
2001 |
Patricelli MP, Cravatt BF. Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides. Vitamins and Hormones. 62: 95-131. PMID 11345902 DOI: 10.1016/S0083-6729(01)62002-8 |
0.514 |
|
2000 |
Boger DL, Fecik RA, Patterson JE, Miyauchi H, Patricelli MP, Cravatt BF. Fatty acid amide hydrolase substrate specificity. Bioorganic & Medicinal Chemistry Letters. 10: 2613-6. PMID 11128635 DOI: 10.1016/S0960-894X(00)00528-X |
0.568 |
|
2000 |
Boger DL, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, Wilkie GD, Austin BJ, Patricelli MP, Cravatt BF. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. Proceedings of the National Academy of Sciences of the United States of America. 97: 5044-9. PMID 10805767 DOI: 10.1073/Pnas.97.10.5044 |
0.608 |
|
2000 |
Patricelli MP, Cravatt BF. Clarifying the catalytic roles of conserved residues in the amidase signature family. The Journal of Biological Chemistry. 275: 19177-84. PMID 10764768 DOI: 10.1074/Jbc.M001607200 |
0.571 |
|
1999 |
Liu Y, Patricelli MP, Cravatt BF. Activity-based protein profiling: the serine hydrolases. Proceedings of the National Academy of Sciences of the United States of America. 96: 14694-9. PMID 10611275 DOI: 10.1073/Pnas.96.26.14694 |
0.543 |
|
1999 |
Patricelli MP, Cravatt BF. Fatty acid amide hydrolase competitively degrades bioactive amides and esters through a nonconventional catalytic mechanism. Biochemistry. 38: 14125-30. PMID 10571985 DOI: 10.1021/Bi991876P |
0.558 |
|
1999 |
Patricelli MP, Lovato MA, Cravatt BF. Chemical and mutagenic investigations of fatty acid amide hydrolase: evidence for a family of serine hydrolases with distinct catalytic properties. Biochemistry. 38: 9804-12. PMID 10433686 DOI: 10.1021/Bi990637Z |
0.55 |
|
1999 |
Boger DL, Sato H, Lerner AE, Austin BJ, Patterson JE, Patricelli MP, Cravatt BF. Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition. Bioorganic & Medicinal Chemistry Letters. 9: 265-70. PMID 10021942 DOI: 10.1016/S0960-894X(98)00734-3 |
0.602 |
|
1998 |
Patricelli MP, Patterson JE, Boger DL, Cravatt BF. An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 8: 613-8. PMID 9871570 DOI: 10.1016/S0960-894X(98)00073-0 |
0.574 |
|
1998 |
Patricelli MP, Lashuel HA, Giang DK, Kelly JW, Cravatt BF. Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization. Biochemistry. 37: 15177-87. PMID 9790682 DOI: 10.1021/Bi981733N |
0.516 |
|
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