Year |
Citation |
Score |
2024 |
Wiesman AI, Madge V, Fon EA, Dagher A, Collins DL, Baillet S. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38405952 DOI: 10.1101/2024.02.16.24302958 |
0.336 |
|
2023 |
Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, Pellitero EDC, Chen CX, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, ... ... Fon EA, et al. The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Biorxiv : the Preprint Server For Biology. PMID 38014143 DOI: 10.1101/2023.11.11.566693 |
0.361 |
|
2023 |
Yu E, Larivière R, Thomas RA, Liu L, Senkevich K, Rahayel S, Trempe JF, Fon EA, Gan-Or Z. Machine learning nominates the inositol pathway and novel genes in Parkinson's disease. Brain : a Journal of Neurology. PMID 37804111 DOI: 10.1093/brain/awad345 |
0.305 |
|
2023 |
Eldeeb MA, Soumbasis A, Fon EA. How does mitochondrial import machinery fine-tune mitophagy? Different paths and one destination. Trends in Endocrinology and Metabolism: Tem. 34: 427-429. PMID 37321958 DOI: 10.1016/j.tem.2023.05.005 |
0.318 |
|
2022 |
Senkevich K, Zorca CE, Dworkind A, Rudakou U, Somerville E, Yu E, Ermolaev A, Nikanorova D, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, ... ... Fon EA, et al. GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. Brain : a Journal of Neurology. PMID 36370000 DOI: 10.1093/brain/awac413 |
0.714 |
|
2022 |
Hu J, Waters CH, Spiegelman D, Fon EA, Yu E, Asayesh F, Krohn L, Saini P, Alcalay RN, Hassin-Baer S, Gan-Or Z, Krainc D, Zhang B, Bustos BI, Lubbe SJ. Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's disease cohorts of European descent. Neurobiology of Aging. 119: 136-138. PMID 36305379 DOI: 10.1016/j.neurobiolaging.2022.07.012 |
0.301 |
|
2022 |
Sheta R, Teixeira M, Idi W, Pierre M, de Rus Jacquet A, Emond V, Zorca CE, Vanderperre B, Durcan TM, Fon EA, Calon F, Chahine M, Oueslati A. Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons. Scientific Reports. 12: 17176. PMID 36229560 DOI: 10.1038/s41598-022-22158-4 |
0.714 |
|
2022 |
Bayati A, Banks E, Han C, Luo W, Reintsch WE, Zorca CE, Shlaifer I, Del Cid Pellitero E, Vanderperre B, McBride HM, Fon EA, Durcan TM, McPherson PS. Rapid macropinocytic transfer of α-synuclein to lysosomes. Cell Reports. 40: 111102. PMID 35858558 DOI: 10.1016/j.celrep.2022.111102 |
0.716 |
|
2022 |
Goiran T, Eldeeb MA, Zorca CE, Fon EA. Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson's Disease. Cells. 11. PMID 35805181 DOI: 10.3390/cells11132097 |
0.761 |
|
2022 |
Chen CX, You Z, Abdian N, Sirois J, Shlaifer I, Tabatabaei M, Boivin MN, Gaborieau L, Karamchandani J, Beitel LK, Fon EA, Durcan TM. Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing. Stem Cell Research. 62: 102806. PMID 35561458 DOI: 10.1016/j.scr.2022.102806 |
0.325 |
|
2022 |
Eldeeb MA, Thomas RA, Ragheb MA, Fallahi A, Fon EA. Mitochondrial quality control in health and in Parkinson's disease. Physiological Reviews. PMID 35466694 DOI: 10.1152/physrev.00041.2021 |
0.404 |
|
2022 |
Vranas M, Lu Y, Rasool S, Croteau N, Krett JD, Sauvé V, Gehring K, Fon EA, Durcan TM, Trempe JF. Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria. Open Biology. 12: 210255. PMID 35042405 DOI: 10.1098/rsob.210255 |
0.354 |
|
2022 |
Rasool S, Veyron S, Soya N, Eldeeb MA, Lukacs GL, Fon EA, Trempe JF. Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Molecular Cell. 82: 44-59.e6. PMID 34875213 DOI: 10.1016/j.molcel.2021.11.012 |
0.311 |
|
2020 |
Roberts RF, Bayne AN, Goiran T, Lévesque D, Boisvert FM, Trempe JF, Fon EA. Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones. Journal of Proteome Research. PMID 33242952 DOI: 10.1021/acs.jproteome.0c00506 |
0.358 |
|
2020 |
Yu E, Rudakou U, Krohn L, Mufti K, Ruskey JA, Asayesh F, Estiar MA, Spiegelman D, Surface M, Fahn S, Waters CH, Greenbaum L, Espay AJ, Dauvilliers Y, Dupré N, ... ... Fon EA, et al. Analysis of Heterozygous PRKN Variants and Copy-Number Variations in Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32970363 DOI: 10.1002/mds.28299 |
0.314 |
|
2019 |
De Snoo ML, Friesen EL, Zhang YT, Earnshaw R, Dorval G, Kapadia M, O'Hara DM, Agapova V, Chau H, Pellerito O, Tang MY, Wang X, Schmitt-Ulms G, Durcan TM, Fon EA, et al. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell Death & Disease. 10: 907. PMID 31787745 DOI: 10.1038/S41419-019-2132-X |
0.346 |
|
2019 |
Eldeeb MA, MacDougall EJ, Ragheb MA, Fon EA. Beyond ER: Regulating TOM-Complex-Mediated Import by Ubx2. Trends in Cell Biology. PMID 31358413 DOI: 10.1016/j.tcb.2019.07.003 |
0.318 |
|
2019 |
Yi W, MacDougall EJ, Tang MY, Krahn AI, Gan-Or Z, Trempe JF, Fon EA. The Landscape of Parkin Variants Reveals Pathogenic Mechanisms and Therapeutic Targets in Parkinson's Disease. Human Molecular Genetics. PMID 30994895 DOI: 10.1093/hmg/ddz080 |
0.335 |
|
2019 |
Alcalay RN, Mallett V, Vanderperre B, Tavassoly O, Dauvilliers Y, Wu RYJ, Ruskey JA, Leblond CS, Ambalavanan A, Laurent SB, Spiegelman D, Dionne-Laporte A, Liong C, Levy OA, Fahn S, ... ... Fon EA, et al. SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30788890 DOI: 10.1002/Mds.27642 |
0.319 |
|
2019 |
Mohamed NV, Larroquette F, Beitel LK, Fon EA, Durcan TM. One Step Into the Future: New iPSC Tools to Advance Research in Parkinson's Disease and Neurological Disorders. Journal of Parkinson's Disease. PMID 30741685 DOI: 10.3233/JPD-181515 |
0.308 |
|
2018 |
Rudakou U, Ouled Amar Bencheikh B, Ruskey JA, Krohn L, Laurent SB, Spiegelman D, Liong C, Fahn S, Waters C, Monchi O, Fon EA, Dauvilliers Y, Alcalay RN, Dupré N, Gan-Or Z. Common and rare GCH1 variants are associated with Parkinson's disease. Neurobiology of Aging. PMID 30314816 DOI: 10.1016/J.Neurobiolaging.2018.09.008 |
0.3 |
|
2018 |
McLelland GL, Fon EA. MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER. Autophagy. PMID 30081712 DOI: 10.1080/15548627.2018.1505154 |
0.335 |
|
2018 |
McLelland GL, Goiran T, Yi W, Dorval G, Chen CX, Lauinger ND, Krahn AI, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 7. PMID 29676259 DOI: 10.7554/eLife.32866 |
0.316 |
|
2018 |
Ross JP, Mohtashami S, Leveille E, Johnson AM, Xiong L, Dion PA, Fon E, Dauvilliers Y, Dupré N, Rouleau GA, Gan-Or Z. Association study of essential tremor genetic loci in Parkinson's disease. Neurobiology of Aging. PMID 29398123 DOI: 10.1016/J.Neurobiolaging.2018.01.001 |
0.379 |
|
2016 |
McLelland GL, Lee SA, McBride HM, Fon EA. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. The Journal of Cell Biology. PMID 27458136 DOI: 10.1083/jcb.201603105 |
0.367 |
|
2016 |
Roberts RF, Tang MY, Fon EA, Durcan TM. Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles. The International Journal of Biochemistry & Cell Biology. PMID 27443527 DOI: 10.1016/j.biocel.2016.07.020 |
0.365 |
|
2015 |
Durcan TM, Fon EA. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes & Development. 29: 989-99. PMID 25995186 DOI: 10.1101/gad.262758.115 |
0.403 |
|
2015 |
Ryan BJ, Hoek S, Fon EA, Wade-Martins R. Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease. Trends in Biochemical Sciences. 40: 200-10. PMID 25757399 DOI: 10.1016/j.tibs.2015.02.003 |
0.43 |
|
2015 |
Durcan TM, Fon EA. USP8 and PARK2/parkin-mediated mitophagy. Autophagy. 11: 428-9. PMID 25700639 DOI: 10.1080/15548627.2015.1009794 |
0.371 |
|
2015 |
Aguileta MA, Korac J, Durcan TM, Trempe JF, Haber M, Gehring K, Elsasser S, Waidmann O, Fon EA, Husnjak K. The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13. The Journal of Biological Chemistry. 290: 7492-505. PMID 25666615 DOI: 10.1074/jbc.M114.614925 |
0.737 |
|
2015 |
Bertolin G, Jacoupy M, Traver S, Ferrando-Miguel R, Saint Georges T, Grenier K, Ardila-Osorio H, Muriel MP, Takahashi H, Lees AJ, Gautier C, Guedin D, Coge F, Fon EA, Brice A, et al. Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. Cell Death and Differentiation. PMID 25591737 DOI: 10.1038/cdd.2014.224 |
0.521 |
|
2015 |
Schreij AM, Chaineau M, Ruan W, Lin S, Barker PA, Fon EA, McPherson PS. LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. Embo Reports. 16: 79-86. PMID 25427558 DOI: 10.15252/Embr.201438714 |
0.378 |
|
2014 |
Grenier K, Kontogiannea M, Fon EA. Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy. The Journal of Biological Chemistry. 289: 29519-30. PMID 25217637 DOI: 10.1074/jbc.M114.607150 |
0.444 |
|
2014 |
Durcan TM, Tang MY, Pérusse JR, Dashti EA, Aguileta MA, McLelland GL, Gros P, Shaler TA, Faubert D, Coulombe B, Fon EA. USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. The Embo Journal. 33: 2473-91. PMID 25216678 DOI: 10.15252/Embj.201489729 |
0.75 |
|
2014 |
Sugiura A, McLelland GL, Fon EA, McBride HM. A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. The Embo Journal. 33: 2142-56. PMID 25107473 DOI: 10.15252/embj.201488104 |
0.39 |
|
2014 |
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature. 510: 162-6. PMID 24784582 DOI: 10.1038/nature13392 |
0.327 |
|
2014 |
McLelland GL, Soubannier V, Chen CX, McBride HM, Fon EA. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. The Embo Journal. 33: 282-95. PMID 24446486 DOI: 10.1002/embj.201385902 |
0.442 |
|
2014 |
Trempe J, Krett J, Sauvé V, Seirafi M, Grenier K, Tang M, Gehring k, Fon E. Catalysis of ubiquitin transfer by the RBR ubiquitin ligase parkin Acta Crystallographica Section a Foundations and Advances. 70: C845-C845. DOI: 10.1107/S2053273314091542 |
0.442 |
|
2013 |
Bertolin G, Ferrando-Miguel R, Jacoupy M, Traver S, Grenier K, Greene AW, Dauphin A, Waharte F, Bayot A, Salamero J, Lombès A, Bulteau AL, Fon EA, Brice A, Corti O. The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance. Autophagy. 9: 1801-17. PMID 24149440 DOI: 10.4161/auto.25884 |
0.421 |
|
2013 |
Grenier K, McLelland GL, Fon EA. Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? Frontiers in Neurology. 4: 100. PMID 23882257 DOI: 10.3389/fneur.2013.00100 |
0.411 |
|
2013 |
Trempe JF, Fon EA. Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection. Frontiers in Neurology. 4: 38. PMID 23626584 DOI: 10.3389/fneur.2013.00038 |
0.357 |
|
2012 |
Grimes D, Gordon J, Snelgrove B, Lim-Carter I, Fon E, Martin W, Wieler M, Suchowersky O, Rajput A, Lafontaine AL, Stoessl J, Moro E, Schoffer K, Miyasaki J, Hobson D, et al. Canadian Guidelines on Parkinson's Disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: S1-30. PMID 23126020 DOI: 10.1017/S031716710001516X |
0.367 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Fon EA, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.305 |
|
2012 |
Greene AW, Grenier K, Aguileta MA, Muise S, Farazifard R, Haque ME, McBride HM, Park DS, Fon EA. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. Embo Reports. 13: 378-85. PMID 22354088 DOI: 10.1038/Embor.2012.14 |
0.742 |
|
2012 |
Soubannier V, McLelland GL, Zunino R, Braschi E, Rippstein P, Fon EA, McBride HM. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Current Biology : Cb. 22: 135-41. PMID 22226745 DOI: 10.1016/j.cub.2011.11.057 |
0.337 |
|
2011 |
Durcan TM, Fon EA. Mutant ataxin-3 promotes the autophagic degradation of parkin. Autophagy. 7: 233-4. PMID 21116127 DOI: 10.4161/auto.7.2.14224 |
0.378 |
|
2011 |
Durcan TM, Kontogiannea M, Thorarinsdottir T, Fallon L, Williams AJ, Djarmati A, Fantaneanu T, Paulson HL, Fon EA. The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Human Molecular Genetics. 20: 141-54. PMID 20940148 DOI: 10.1093/hmg/ddq452 |
0.305 |
|
2010 |
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, ... ... Fon EA, et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Molecular Genetics. 19: 3734-46. PMID 20639397 DOI: 10.1093/Hmg/Ddq288 |
0.409 |
|
2009 |
Trempe JF, Chen CX, Grenier K, Camacho EM, Kozlov G, McPherson PS, Gehring K, Fon EA. SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination. Molecular Cell. 36: 1034-47. PMID 20064468 DOI: 10.1016/J.Molcel.2009.11.021 |
0.325 |
|
2007 |
Cookson MR, Dauer W, Dawson T, Fon EA, Guo M, Shen J. The roles of kinases in familial Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11865-8. PMID 17978026 DOI: 10.1523/Jneurosci.3695-07.2007 |
0.345 |
|
2007 |
Joch M, Ase AR, Chen CX, MacDonald PA, Kontogiannea M, Corera AT, Brice A, Séguéla P, Fon EA. Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels. Molecular Biology of the Cell. 18: 3105-18. PMID 17553932 DOI: 10.1091/Mbc.E05-11-1027 |
0.353 |
|
2006 |
Fallon L, Bélanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, Brice A, van Bergen En Henegouwen PM, Fon EA. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nature Cell Biology. 8: 834-42. PMID 16862145 DOI: 10.1038/Ncb1441 |
0.307 |
|
2005 |
Croft BG, Fortin GD, Corera AT, Edwards RH, Beaudet A, Trudeau LE, Fon EA. Normal biogenesis and cycling of empty synaptic vesicles in dopamine neurons of vesicular monoamine transporter 2 knockout mice. Molecular Biology of the Cell. 16: 306-15. PMID 15496457 DOI: 10.1091/Mbc.E04-07-0559 |
0.418 |
|
2004 |
Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM. BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Neuron. 44: 931-45. PMID 15603737 DOI: 10.1016/J.Neuron.2004.11.026 |
0.388 |
|
2002 |
Alvarez C, Vitalis T, Fon EA, Hanoun N, Hamon M, Seif I, Edwards R, Gaspar P, Cases O. Effects of genetic depletion of monoamines on somatosensory cortical development. Neuroscience. 115: 753-64. PMID 12435414 DOI: 10.1016/S0306-4522(02)00484-0 |
0.403 |
|
2002 |
Larsen KE, Fon EA, Hastings TG, Edwards RH, Sulzer D. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8951-60. PMID 12388602 DOI: 10.1523/Jneurosci.22-20-08951.2002 |
0.434 |
|
2001 |
Fon EA, Edwards RH. Molecular mechanisms of neurotransmitter release. Muscle & Nerve. 24: 581-601. PMID 11317268 DOI: 10.1002/mus.1044 |
0.405 |
|
1998 |
Reimer RJ, Fon EA, Edwards RH. Vesicular neurotransmitter transport and the presynaptic regulation of quantal size. Current Opinion in Neurobiology. 8: 405-12. PMID 9687352 DOI: 10.1016/S0959-4388(98)80068-8 |
0.656 |
|
1997 |
Fon EA, Pothos EN, Sun BC, Killeen N, Sulzer D, Edwards RH. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron. 19: 1271-83. PMID 9427250 DOI: 10.1016/S0896-6273(00)80418-3 |
0.397 |
|
1997 |
Song H, Ming G, Fon E, Bellocchio E, Edwards RH, Poo M. Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging. Neuron. 18: 815-26. PMID 9182805 DOI: 10.1016/S0896-6273(00)80320-7 |
0.712 |
|
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