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Ana Garcia-Osta - Publications

Affiliations: 
CIMA, Pamplona, Pamplona, Navarra, Spain 
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Badesso S, Cartas-Cejudo P, Espelosin M, Santamaria E, Cuadrado-Tejedor M, Garcia-Osta A. Docosahexaenoic Acid Ameliorates Contextual Fear Memory Deficits in the Tg2576 Alzheimer's Disease Mouse Model: Cellular and Molecular Correlates. Pharmaceutics. 15. PMID 36678710 DOI: 10.3390/pharmaceutics15010082  0.373
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818  0.355
2019 Gil-Iturbe E, Solas M, Cuadrado-Tejedo M, García-Osta A, Escoté X, Ramírez MJ, Lostao MP. GLUT12 Expression in Brain of Mouse Models of Alzheimer's Disease. Molecular Neurobiology. PMID 31473905 DOI: 10.1007/S12035-019-01743-1  0.32
2019 Cuadrado-Tejedor M, Pérez-González M, García-Muñoz C, Muruzabal D, García-Barroso C, Rabal O, Segura V, Sánchez-Arias JA, Oyarzabal J, Garcia-Osta A. Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer's Disease. Frontiers in Aging Neuroscience. 11: 149. PMID 31281249 DOI: 10.3389/fnagi.2019.00149  0.374
2018 Ugarte A, Corbacho D, Aymerich MS, García-Osta A, Cuadrado-Tejedor M, Oyarzabal J. Impact of Neurodegenerative Diseases on Drug Binding to Brain Tissues: From Animal Models to Human Samples. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 29675823 DOI: 10.1007/s13311-018-0624-5  0.317
2018 Lasarte-Cia A, Lozano T, Pérez-González M, Gorraiz M, Iribarren K, Hervás-Stubbs S, Sarobe P, Rabal O, Cuadrado-Tejedor M, García-Osta A, Casares N, Lasarte JJ. Immunomodulatory Properties of Carvone Inhalation and Its Effects on Contextual Fear Memory in Mice. Frontiers in Immunology. 9: 68. PMID 29422905 DOI: 10.3389/fimmu.2018.00068  0.398
2016 Sánchez-Arias JA, Rabal O, Cuadrado-Tejedor M, De Miguel I, Pérez-González M, Ugarte A, Sáez E, Espelosin M, Ursua S, Haizhong T, Wei W, Musheng X, Garcia-Osta A, Oyarzabal J. Impact of scaffold exploration on novel dual-acting histone deacetylases (HDACs) and phosphodiesterase 5 (PDE5) inhibitors for the treatment of Alzheimer's Disease. Acs Chemical Neuroscience. PMID 27936591 DOI: 10.1021/acschemneuro.6b00370  0.331
2016 Rabal O, Sánchez-Arias JA, Cuadrado-Tejedor M, De Miguel I, Pérez-González M, García-Barroso C, Ugarte A, Estella-Hermoso de Mendoza A, Sáez E, Espelosin M, Ursua S, Haizhong T, Wei W, Musheng X, Garcia-Osta A, et al. Design, synthesis, and biological evaluation of first-in-class dual acting histone deacetylases (HDACs) and phosphodiesterase 5 (PDE5) inhibitors for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. PMID 27606546 DOI: 10.1021/acs.jmedchem.6b00908  0.314
2016 Cuadrado-Tejedor M, Garcia-Barroso C, Sánchez-Arias JA, Rabal O, Pérez-González M, Mederos S, Ugarte A, Franco R, Segura V, Perea G, Oyarzabal J, Garcia-Osta A. A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5, and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27550730 DOI: 10.1038/npp.2016.163  0.383
2016 Cuadrado-Tejedor M, García-Osta A. Chronic Mild Stress Assay Leading to Early Onset and Propagation of Alzheimer's Disease Phenotype in Mouse Models. Methods in Molecular Biology (Clifton, N.J.). 1303: 241-6. PMID 26235071 DOI: 10.1007/978-1-4939-2627-5_14  0.348
2016 García-Osta A, Cuadrado-Tejedor M. Advanced Assay Monitoring APP-Carboxyl-Terminal Fragments as Markers of APP Processing in Alzheimer Disease Mouse Models. Methods in Molecular Biology (Clifton, N.J.). 1303: 117-23. PMID 26235062 DOI: 10.1007/978-1-4939-2627-5_5  0.313
2015 Peixoto CA, Nunes AK, Garcia-Osta A. Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition. Mediators of Inflammation. 2015: 940207. PMID 26770022 DOI: 10.1155/2015/940207  0.435
2015 Cuadrado-Tejedor M, Garcia-Barroso C, Sanzhez-Arias J, Mederos S, Rabal O, Ugarte A, Franco R, Pascual-Lucas M, Segura V, Perea G, Oyarzabal J, Garcia-Osta A. Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer's disease. Clinical Epigenetics. 7: 108. PMID 26457123 DOI: 10.1186/s13148-015-0142-9  0.418
2015 Ugarte A, Gil-Bea F, García-Barroso C, Cedazo-Minguez Á, Ramírez MJ, Franco R, García-Osta A, Oyarzabal J, Cuadrado-Tejedor M. Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease. Neuropathology and Applied Neurobiology. 41: 471-82. PMID 25488891 DOI: 10.1111/nan.12203  0.368
2014 Cuadrado-Tejedor M, García-Osta A. Current animal models of Alzheimer's disease: challenges in translational research. Frontiers in Neurology. 5: 182. PMID 25324824 DOI: 10.3389/fneur.2014.00182  0.413
2014 García-Barroso C, Ugarte A, Martínez M, Rico AJ, Lanciego JL, Franco R, Oyarzabal J, Cuadrado-Tejedor M, García-Osta A. Phosphodiesterase inhibition in cognitive decline. Journal of Alzheimer's Disease : Jad. 42: S561-73. PMID 25125473 DOI: 10.3233/JAD-141341  0.516
2014 Pascual-Lucas M, Viana da Silva S, Di Scala M, Garcia-Barroso C, González-Aseguinolaza G, Mulle C, Alberini CM, Cuadrado-Tejedor M, Garcia-Osta A. Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice. Embo Molecular Medicine. 6: 1246-62. PMID 25100745 DOI: 10.15252/Emmm.201404228  0.655
2013 Cuadrado-Tejedor M, Oyarzabal J, Lucas MP, Franco R, García-Osta A. Epigenetic drugs in Alzheimer's disease. Biomolecular Concepts. 4: 433-45. PMID 25436752 DOI: 10.1515/bmc-2013-0012  0.377
2013 Cuadrado-Tejedor M, Ricobaraza AL, Torrijo R, Franco R, Garcia-Osta A. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. Current Pharmaceutical Design. 19: 5076-84. PMID 23448463 DOI: 10.2174/1381612811319280006  0.349
2012 Cuadrado-Tejedor M, Ricobaraza A, Frechilla D, Franco R, Pérez-Mediavilla A, Garcia-Osta A. Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice. Journal of Alzheimer's Disease : Jad. 28: 567-78. PMID 22045482 DOI: 10.3233/JAD-2011-110572  0.363
2011 Ricobaraza A, Cuadrado-Tejedor M, Garcia-Osta A. Long-term phenylbutyrate administration prevents memory deficits in Tg2576 mice by decreasing Abeta. Frontiers in Bioscience (Elite Edition). 3: 1375-84. PMID 21622143 DOI: 10.2741/E340  0.542
2011 Chen DY, Stern SA, Garcia-Osta A, Saunier-Rebori B, Pollonini G, Bambah-Mukku D, Blitzer RD, Alberini CM. A critical role for IGF-II in memory consolidation and enhancement. Nature. 469: 491-7. PMID 21270887 DOI: 10.1038/Nature09667  0.609
2011 Cuadrado-Tejedor M, Ricobaraza A, Del Río J, Frechilla D, Franco R, Pérez-Mediavilla A, Garcia-Osta A. Chronic mild stress in mice promotes cognitive impairment and CDK5-dependent tau hyperphosphorylation. Behavioural Brain Research. 220: 338-43. PMID 21238494 DOI: 10.1016/j.bbr.2011.01.005  0.327
2011 Okvist A, Fagergren P, Whittard J, Garcia-Osta A, Drakenberg K, Horvath MC, Schmidt CJ, Keller E, Bannon MJ, Hurd YL. Dysregulated postsynaptic density and endocytic zone in the amygdala of human heroin and cocaine abusers. Biological Psychiatry. 69: 245-52. PMID 21126734 DOI: 10.1016/J.Biopsych.2010.09.037  0.344
2010 Taubenfeld SM, Muravieva EV, Garcia-Osta A, Alberini CM. Disrupting the memory of places induced by drugs of abuse weakens motivational withdrawal in a context-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 107: 12345-50. PMID 20566855 DOI: 10.1073/pnas.1003152107  0.59
2009 Garcia-Osta A, Alberini CM. Amyloid beta mediates memory formation. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 267-72. PMID 19318468 DOI: 10.1101/lm.1310209  0.648
2008 Mathews PM, Garcia-Osta A, Mazzella MJ, Alberini CM. O2-02-01: Endogenous Aβ enhances memory retention in the rat Alzheimer's & Dementia. 4: T133-T133. DOI: 10.1016/J.Jalz.2008.05.313  0.676
2006 Garcia-Osta A, Tsokas P, Pollonini G, Landau EM, Blitzer R, Alberini CM. MuSK expressed in the brain mediates cholinergic responses, synaptic plasticity, and memory formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7919-32. PMID 16870737 DOI: 10.1523/Jneurosci.1674-06.2006  0.714
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