Joseph S. Takahashi, B.A., Ph.D. - Publications

Affiliations: 
HHMI, Department of Neuroscience University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Circadian Clocks, Neuroscience, Genetics
Website:
http://profiles.utsouthwestern.edu/profile/105885/joseph-takahashi.html

260 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, et al. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metabolism. PMID 30827863 DOI: 10.1016/j.cmet.2019.01.023  0.76
2019 Beytebiere JR, Trott AJ, Greenwell BJ, Osborne CA, Vitet H, Spence J, Yoo SH, Chen Z, Takahashi JS, Ghaffari N, Menet JS. Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer-enhancer interactions. Genes & Development. PMID 30804225 DOI: 10.1101/gad.322198.118  0.96
2018 Corty RW, Kumar V, Tarantino LM, Takahashi JS, Valdar W. Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice. G3 (Bethesda, Md.). PMID 30389793 DOI: 10.1534/g3.118.200194  1
2018 Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, et al. Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Reports. 25: 1-9.e5. PMID 30282019 DOI: 10.1016/j.celrep.2018.09.015  0.52
2018 Rosensweig C, Reynolds KA, Gao P, Laothamatas I, Shan Y, Ranganathan R, Takahashi JS, Green CB. An evolutionary hotspot defines functional differences between CRYPTOCHROMES. Nature Communications. 9: 1138. PMID 29556064 DOI: 10.1038/s41467-018-03503-6  0.68
2018 Ye Y, Xiang Y, Ozguc FM, Kim Y, Liu CJ, Park PK, Hu Q, Diao L, Lou Y, Lin C, Guo AY, Zhou B, Wang L, Chen Z, Takahashi JS, et al. The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy. Cell Systems. PMID 29525205 DOI: 10.1016/j.cels.2018.01.013  0.96
2018 Rijo-Ferreira F, Carvalho T, Afonso C, Sanches-Vaz M, Costa RM, Figueiredo LM, Takahashi JS. Sleeping sickness is a circadian disorder. Nature Communications. 9: 62. PMID 29302035 DOI: 10.1038/s41467-017-02484-2  0.36
2017 Fontenot MR, Berto S, Liu Y, Werthmann G, Douglas C, Usui N, Gleason K, Tamminga CA, Takahashi JS, Konopka G. Novel transcriptional networks regulated by CLOCK in human neurons. Genes & Development. 31: 2121-2135. PMID 29196536 DOI: 10.1101/gad.305813.117  0.4
2017 Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, ... ... Takahashi JS, et al. Guidelines for Genome-Scale Analysis of Biological Rhythms. Journal of Biological Rhythms. 748730417728663. PMID 29098954 DOI: 10.1177/0748730417728663  1
2017 Rijo-Ferreira F, Takahashi JS, Figueiredo LM. Circadian rhythms in parasites. Plos Pathogens. 13: e1006590. PMID 29023533 DOI: 10.1371/journal.ppat.1006590  0.36
2017 Yoo SH, Kojima S, Shimomura K, Koike N, Buhr ED, Furukawa T, Ko CH, Gloston G, Ayoub C, Nohara K, Reyes BA, Tsuchiya Y, Yoo OJ, Yagita K, Lee C, ... ... Takahashi JS, et al. Period2 3'-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973913 DOI: 10.1073/pnas.1706611114  1
2017 Sun L, Jiang Z, Acosta-Rodriguez VA, Berger M, Du X, Choi JH, Wang J, Wang KW, Kilaru GK, Mohawk JA, Quan J, Scott L, Hildebrand S, Li X, Tang M, ... ... Takahashi JS, et al. HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections. The Journal of Experimental Medicine. PMID 28970238 DOI: 10.1084/jem.20161630  1
2017 Taniguchi M, Carreira MB, Cooper YA, Bobadilla AC, Heinsbroek JA, Koike N, Larson EB, Balmuth EA, Hughes BW, Penrod RD, Kumar J, Smith LN, Guzman D, Takahashi JS, Kim TK, et al. HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors. Neuron. 96: 130-144.e6. PMID 28957664 DOI: 10.1016/j.neuron.2017.09.015  0.76
2017 Wang H, van Spyk E, Liu Q, Geyfman M, Salmans ML, Kumar V, Ihler A, Li N, Takahashi JS, Andersen B. Time-Restricted Feeding Shifts the Skin Circadian Clock and Alters UVB-Induced DNA Damage. Cell Reports. 20: 1061-1072. PMID 28768192 DOI: 10.1016/j.celrep.2017.07.022  1
2017 Ehlen JC, Brager AJ, Baggs J, Pinckney L, Gray CL, DeBruyne JP, Esser KA, Takahashi JS, Paul KN. Bmal1 function in skeletal muscle regulates sleep. Elife. 6. PMID 28726633 DOI: 10.7554/eLife.26557  0.44
2017 Acosta-Rodríguez VA, de Groot MHM, Rijo-Ferreira F, Green CB, Takahashi JS. Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System. Cell Metabolism. 26: 267-277.e2. PMID 28683292 DOI: 10.1016/j.cmet.2017.06.007  0.68
2017 Rijo-Ferreira F, Pinto-Neves D, Barbosa-Morais NL, Takahashi JS, Figueiredo LM. Trypanosoma brucei metabolism is under circadian control. Nature Microbiology. 2: 17032. PMID 28288095 DOI: 10.1038/nmicrobiol.2017.32  0.36
2017 Michael AK, Fribourgh JL, Chelliah Y, Sandate CR, Hura GL, Schneidman-Duhovny D, Tripathi SM, Takahashi JS, Partch CL. Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143926 DOI: 10.1073/pnas.1615310114  0.68
2016 Lee WH, Higuchi H, Ikeda S, Macke EL, Takimoto T, Pattnaik BR, Liu C, Chu LF, Siepka SM, Krentz KJ, Rubinstein CD, Kalejta RF, Thomson JA, Mullins RF, Takahashi JS, et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. Elife. 5. PMID 27863209 DOI: 10.7554/eLife.19264  1
2016 Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, ... ... Takahashi JS, et al. Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. PMID 27806374 DOI: 10.1038/nature20142  1
2016 Qu Z, Zhang H, Huang M, Shi G, Liu Z, Xie P, Li H, Wang W, Xu G, Zhang Y, Yang L, Huang G, Takahashi JS, Zhang WJ, Xu Y. Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms. Elife. 5. PMID 27657167 DOI: 10.7554/eLife.17171  1
2016 Huang G, Zhang Y, Shan Y, Yang S, Chelliah Y, Wang H, Takahashi JS. Circadian Oscillations of NADH Redox State Using a Heterologous Metabolic Sensor in Mammalian Cells. The Journal of Biological Chemistry. PMID 27645993 DOI: 10.1074/jbc.M116.728774  0.48
2016 Hossain MS, Asano F, Fujiyama T, Miyoshi C, Sato M, Ikkyu A, Kanno S, Hotta N, Kakizaki M, Honda T, Kim SJ, Komiya H, Miura I, Suzuki T, Kobayashi K, ... ... Takahashi JS, et al. Identification of mutations through dominant screening for obesity using C57BL/6 substrains. Scientific Reports. 6: 32453. PMID 27585985 DOI: 10.1038/srep32453  1
2016 He B, Nohara K, Park N, Park YS, Guillory B, Zhao Z, Garcia JM, Koike N, Lee CC, Takahashi JS, Yoo SH, Chen Z. The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. Cell Metabolism. 23: 610-21. PMID 27076076 DOI: 10.1016/j.cmet.2016.03.007  1
2015 Pagani L, St Clair PA, Teshiba TM, Service SK, Fears SC, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Makhinson J, Lopez MC, Montoya G, Montoya CP, Aldana I, ... ... Takahashi JS, et al. Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712028 DOI: 10.1073/pnas.1513525113  1
2015 Wang GZ, Hickey SL, Shi L, Huang HC, Nakashe P, Koike N, Tu BP, Takahashi JS, Konopka G. Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale. Cell Reports. 13: 1868-1880. PMID 26655902 DOI: 10.1016/j.celrep.2015.10.043  1
2015 D'Alessandro M, Beesley S, Kim JK, Chen R, Abich E, Cheng W, Yi P, Takahashi JS, Lee C. A tunable artificial circadian clock in clock-defective mice. Nature Communications. 6: 8587. PMID 26617050 DOI: 10.1038/ncomms9587  1
2015 Takahashi JS. Molecular components of the circadian clock in mammals. Diabetes, Obesity & Metabolism. 17: 6-11. PMID 26332962 DOI: 10.1111/dom.12514  1
2015 Lee IT, Chang AS, Manandhar M, Shan Y, Fan J, Izumo M, Ikeda Y, Motoike T, Dixon S, Seinfeld JE, Takahashi JS, Yanagisawa M. Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms. Neuron. 85: 1086-102. PMID 25741729 DOI: 10.1016/j.neuron.2015.02.006  1
2015 Takahashi JS, Kumar V, Nakashe P, Koike N, Huang HC, Green CB, Kim TK. ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals. Methods in Enzymology. 551: 285-321. PMID 25662462 DOI: 10.1016/bs.mie.2014.10.059  1
2015 Fan J, Zeng H, Olson DP, Huber KM, Gibson JR, Takahashi JS. Vasoactive intestinal polypeptide (VIP)-expressing neurons in the suprachiasmatic nucleus provide sparse GABAergic outputs to local neurons with circadian regulation occurring distal to the opening of postsynaptic GABAA ionotropic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1905-20. PMID 25653351 DOI: 10.1523/JNEUROSCI.2661-14.2015  1
2015 Plikus MV, Van Spyk EN, Pham K, Geyfman M, Kumar V, Takahashi JS, Andersen B. The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity. Journal of Biological Rhythms. 30: 163-82. PMID 25589491 DOI: 10.1177/0748730414563537  1
2015 Stringari C, Wang H, Geyfman M, Crosignani V, Kumar V, Takahashi JS, Andersen B, Gratton E. In vivo single-cell detection of metabolic oscillations in stem cells. Cell Reports. 10: 1-7. PMID 25543138 DOI: 10.1016/j.celrep.2014.12.007  1
2014 Izumo M, Pejchal M, Schook AC, Lange RP, Walisser JA, Sato TR, Wang X, Bradfield CA, Takahashi JS. Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant. Elife. 3. PMID 25525750 DOI: 10.7554/eLife.04617  0.76
2014 Johnson BP, Walisser JA, Liu Y, Shen AL, McDearmon EL, Moran SM, McIntosh BE, Vollrath AL, Schook AC, Takahashi JS, Bradfield CA. Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18757-62. PMID 25512522 DOI: 10.1073/pnas.1421708111  1
2014 Umemura Y, Koike N, Matsumoto T, Yoo SH, Chen Z, Yasuhara N, Takahashi JS, Yagita K. Transcriptional program of Kpna2/Importin-α2 regulates cellular differentiation-coupled circadian clock development in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E5039-48. PMID 25389311 DOI: 10.1073/pnas.1419272111  1
2014 Nangle SN, Rosensweig C, Koike N, Tei H, Takahashi JS, Green CB, Zheng N. Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex. Elife. 3: e03674. PMID 25127877 DOI: 10.7554/eLife.03674  1
2014 Nam HJ, Boo K, Kim D, Han DH, Choe HK, Kim CR, Sun W, Kim H, Kim K, Lee H, Metzger E, Schuele R, Yoo SH, Takahashi JS, Cho S, et al. Phosphorylation of LSD1 by PKCα is crucial for circadian rhythmicity and phase resetting. Molecular Cell. 53: 791-805. PMID 24582500 DOI: 10.1016/j.molcel.2014.01.028  1
2014 Partch CL, Green CB, Takahashi JS. Molecular architecture of the mammalian circadian clock. Trends in Cell Biology. 24: 90-9. PMID 23916625 DOI: 10.1016/j.tcb.2013.07.002  1
2013 Miller BH, Takahashi JS. Central circadian control of female reproductive function. Frontiers in Endocrinology. 4: 195. PMID 24478756 DOI: 10.3389/fendo.2013.00195  1
2013 Kumar V, Kim K, Joseph C, Kourrich S, Yoo SH, Huang HC, Vitaterna MH, de Villena FP, Churchill G, Bonci A, Takahashi JS. C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response. Science (New York, N.Y.). 342: 1508-12. PMID 24357318 DOI: 10.1126/science.1245503  1
2013 Kumar V, Andersen B, Takahashi JS. Epidermal stem cells ride the circadian wave. Genome Biology. 14: 140. PMID 24286354 DOI: 10.1186/gb4142  1
2013 Yu X, Rollins D, Ruhn KA, Stubblefield JJ, Green CB, Kashiwada M, Rothman PB, Takahashi JS, Hooper LV. TH17 cell differentiation is regulated by the circadian clock. Science (New York, N.Y.). 342: 727-30. PMID 24202171 DOI: 10.1126/science.1243884  1
2013 Gao P, Yoo SH, Lee KJ, Rosensweig C, Takahashi JS, Chen BP, Green CB. Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length. The Journal of Biological Chemistry. 288: 35277-86. PMID 24158435 DOI: 10.1074/jbc.M113.509604  1
2013 Bookout AL, de Groot MH, Owen BM, Lee S, Gautron L, Lawrence HL, Ding X, Elmquist JK, Takahashi JS, Mangelsdorf DJ, Kliewer SA. FGF21 regulates metabolism and circadian behavior by acting on the nervous system. Nature Medicine. 19: 1147-52. PMID 23933984 DOI: 10.1038/nm.3249  1
2013 Buhr ED, Takahashi JS. Molecular components of the Mammalian circadian clock. Handbook of Experimental Pharmacology. 3-27. PMID 23604473 DOI: 10.1007/978-3-642-25950-0_1  1
2013 Shimomura K, Kumar V, Koike N, Kim TK, Chong J, Buhr ED, Whiteley AR, Low SS, Omura C, Fenner D, Owens JR, Richards M, Yoo SH, Hong HK, Vitaterna MH, ... ... Takahashi JS, et al. Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife. 2: e00426. PMID 23580255 DOI: 10.7554/eLife.00426  1
2013 Yoo SH, Mohawk JA, Siepka SM, Shan Y, Huh SK, Hong HK, Kornblum I, Kumar V, Koike N, Xu M, Nussbaum J, Liu X, Chen Z, Chen ZJ, Green CB, ... Takahashi JS, et al. Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm. Cell. 152: 1091-105. PMID 23452855 DOI: 10.1016/j.cell.2013.01.055  1
2013 Chen Z, Yoo SH, Takahashi JS. Small molecule modifiers of circadian clocks. Cellular and Molecular Life Sciences : Cmls. 70: 2985-98. PMID 23161063 DOI: 10.1007/s00018-012-1207-y  1
2012 Horvath TL, Abizaid A, Dietrich MO, Li Y, Takahashi JS, Bass J. Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center. Molecular Metabolism. 1: 79-85. PMID 24024121 DOI: 10.1016/j.molmet.2012.08.003  1
2012 Koike N, Yoo SH, Huang HC, Kumar V, Lee C, Kim TK, Takahashi JS. Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science (New York, N.Y.). 338: 349-54. PMID 22936566 DOI: 10.1126/science.1226339  1
2012 Hughes ME, Hong HK, Chong JL, Indacochea AA, Lee SS, Han M, Takahashi JS, Hogenesch JB. Brain-specific rescue of Clock reveals system-driven transcriptional rhythms in peripheral tissue. Plos Genetics. 8: e1002835. PMID 22844252 DOI: 10.1371/journal.pgen.1002835  0.92
2012 Geyfman M, Kumar V, Liu Q, Ruiz R, Gordon W, Espitia F, Cam E, Millar SE, Smyth P, Ihler A, Takahashi JS, Andersen B. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proceedings of the National Academy of Sciences of the United States of America. 109: 11758-63. PMID 22753467 DOI: 10.1073/pnas.1209592109  1
2012 Huang N, Chelliah Y, Shan Y, Taylor CA, Yoo SH, Partch C, Green CB, Zhang H, Takahashi JS. Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science (New York, N.Y.). 337: 189-94. PMID 22653727 DOI: 10.1126/science.1222804  1
2012 Mohawk JA, Green CB, Takahashi JS. Central and peripheral circadian clocks in mammals. Annual Review of Neuroscience. 35: 445-62. PMID 22483041 DOI: 10.1146/annurev-neuro-060909-153128  1
2012 Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, Yoo SH, Takahashi JS, Butler AA, Kamenecka TM, Burris TP. Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature. 485: 62-8. PMID 22460951 DOI: 10.1038/nature11030  1
2012 Chen Z, Yoo SH, Park YS, Kim KH, Wei S, Buhr E, Ye ZY, Pan HL, Takahashi JS. Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening. Proceedings of the National Academy of Sciences of the United States of America. 109: 101-6. PMID 22184224 DOI: 10.1073/pnas.1118034108  1
2011 Lowrey PL, Takahashi JS. Genetics of circadian rhythms in Mammalian model organisms. Advances in Genetics. 74: 175-230. PMID 21924978 DOI: 10.1016/B978-0-12-387690-4.00006-4  1
2011 Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J. Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators. The Journal of Biological Chemistry. 286: 39560-72. PMID 21921030 DOI: 10.1074/jbc.M111.269100  1
2011 Kumar V, Kim K, Joseph C, Thomas LC, Hong H, Takahashi JS. Second-generation high-throughput forward genetic screen in mice to isolate subtle behavioral mutants. Proceedings of the National Academy of Sciences of the United States of America. 108: 15557-64. PMID 21896739 DOI: 10.1073/pnas.1107726108  1
2011 Mohawk JA, Takahashi JS. Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators. Trends in Neurosciences. 34: 349-58. PMID 21665298 DOI: 10.1016/j.tins.2011.05.003  1
2011 Dzirasa K, McGarity DL, Bhattacharya A, Kumar S, Takahashi JS, Dunson D, McClung CA, Nicolelis MA. Impaired limbic gamma oscillatory synchrony during anxiety-related behavior in a genetic mouse model of bipolar mania. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6449-56. PMID 21525286 DOI: 10.1523/JNEUROSCI.6144-10.2011  1
2011 Bass J, Takahashi JS. Circadian rhythms: Redox redux. Nature. 469: 476-8. PMID 21270881 DOI: 10.1038/469476a  1
2011 Buhr ED, Yoo SH, Takahashi JS. Phase-resetting sensitivity of the suprachiasmatic nucleus and oscillator amplitude: Reply to letter by Ruby Journal of Biological Rhythms. 26: 371-373. DOI: 10.1177/0748730411411679  1
2010 Bass J, Takahashi JS. Circadian integration of metabolism and energetics. Science (New York, N.Y.). 330: 1349-54. PMID 21127246 DOI: 10.1126/science.1195027  1
2010 Dzirasa K, Coque L, Sidor MM, Kumar S, Dancy EA, Takahashi JS, McClung CA, Nicolelis MA. Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16314-23. PMID 21123577 DOI: 10.1523/JNEUROSCI.4289-10.2010  1
2010 Ko CH, Yamada YR, Welsh DK, Buhr ED, Liu AC, Zhang EE, Ralph MR, Kay SA, Forger DB, Takahashi JS. Emergence of noise-induced oscillations in the central circadian pacemaker. Plos Biology. 8: e1000513. PMID 20967239 DOI: 10.1371/journal.pbio.1000513  1
2010 Morris JA, Royall JJ, Bertagnolli D, Boe AF, Burnell JJ, Byrnes EJ, Copeland C, Desta T, Fischer SR, Goldy J, Glattfelder KJ, Kidney JM, Lemon T, Orta GJ, Parry SE, ... ... Takahashi JS, et al. Divergent and nonuniform gene expression patterns in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 19049-54. PMID 20956311 DOI: 10.1073/pnas.1003732107  1
2010 Andrews JL, Zhang X, McCarthy JJ, McDearmon EL, Hornberger TA, Russell B, Campbell KS, Arbogast S, Reid MB, Walker JR, Hogenesch JB, Takahashi JS, Esser KA. CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function. Proceedings of the National Academy of Sciences of the United States of America. 107: 19090-5. PMID 20956306 DOI: 10.1073/pnas.1014523107  1
2010 Buhr ED, Yoo SH, Takahashi JS. Temperature as a universal resetting cue for mammalian circadian oscillators. Science (New York, N.Y.). 330: 379-85. PMID 20947768 DOI: 10.1126/science.1195262  1
2010 Kumar V, Takahashi JS. PARP around the clock. Cell. 142: 841-3. PMID 20850006 DOI: 10.1016/j.cell.2010.08.037  1
2010 Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, ... ... Takahashi JS, et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 466: 627-31. PMID 20562852 DOI: 10.1038/nature09253  1
2010 Shimomura K, Lowrey PL, Vitaterna MH, Buhr ED, Kumar V, Hanna P, Omura C, Izumo M, Low SS, Barrett RK, LaRue SI, Green CB, Takahashi JS. Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 8399-403. PMID 20404168 DOI: 10.1073/pnas.1004368107  1
2010 Welsh DK, Takahashi JS, Kay SA. Suprachiasmatic nucleus: cell autonomy and network properties. Annual Review of Physiology. 72: 551-77. PMID 20148688 DOI: 10.1146/annurev-physiol-021909-135919  1
2009 Chen R, Schirmer A, Lee Y, Lee H, Kumar V, Yoo SH, Takahashi JS, Lee C. Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism. Molecular Cell. 36: 417-30. PMID 19917250 DOI: 10.1016/j.molcel.2009.10.012  1
2009 Isojima Y, Nakajima M, Ukai H, Fujishima H, Yamada RG, Masumoto KH, Kiuchi R, Ishida M, Ukai-Tadenuma M, Minami Y, Kito R, Nakao K, Kishimoto W, Yoo SH, Shimomura K, ... ... Takahashi JS, et al. CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 106: 15744-9. PMID 19805222 DOI: 10.1073/pnas.0908733106  1
2009 Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE. Identification of genetic loci involved in diabetes using a rat model of depression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 486-97. PMID 19697080 DOI: 10.1007/s00335-009-9211-8  1
2009 Lin KK, Kumar V, Geyfman M, Chudova D, Ihler AT, Smyth P, Paus R, Takahashi JS, Andersen B. Circadian clock genes contribute to the regulation of hair follicle cycling. Plos Genetics. 5: e1000573. PMID 19629164 DOI: 10.1371/journal.pgen.1000573  1
2009 Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva B, Hong HK, Chong JL, Buhr ED, Lee C, Takahashi JS, Imai S, Bass J. Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (New York, N.Y.). 324: 651-4. PMID 19299583 DOI: 10.1126/science.1171641  1
2008 Takahashi JS, Shimomura K, Kumar V. Searching for genes underlying behavior: lessons from circadian rhythms. Science (New York, N.Y.). 322: 909-12. PMID 18988844 DOI: 10.1126/science.1158822  1
2008 Takahashi JS, Hong HK, Ko CH, McDearmon EL. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nature Reviews. Genetics. 9: 764-75. PMID 18802415 DOI: 10.1038/nrg2430  1
2008 Green CB, Takahashi JS, Bass J. The meter of metabolism. Cell. 134: 728-42. PMID 18775307 DOI: 10.1016/j.cell.2008.08.022  1
2008 O'Neill JS, Maywood ES, Chesham JE, Takahashi JS, Hastings MH. cAMP-dependent signaling as a core component of the mammalian circadian pacemaker. Science (New York, N.Y.). 320: 949-53. PMID 18487196 DOI: 10.1126/science.1152506  1
2008 Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, et al. Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. Plos Genetics. 4: e1000070. PMID 18464898 DOI: 10.1371/journal.pgen.1000070  1
2008 Meng QJ, Logunova L, Maywood ES, Gallego M, Lebiecki J, Brown TM, Sládek M, Semikhodskii AS, Glossop NR, Piggins HD, Chesham JE, Bechtold DA, Yoo SH, Takahashi JS, Virshup DM, et al. Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron. 58: 78-88. PMID 18400165 DOI: 10.1016/j.neuron.2008.01.019  1
2007 Siepka SM, Yoo SH, Park J, Lee C, Takahashi JS. Genetics and neurobiology of circadian clocks in mammals. Cold Spring Harbor Symposia On Quantitative Biology. 72: 251-9. PMID 18419282 DOI: 10.1101/sqb.2007.72.052  1
2007 Pinto LH, Invergo B, Shimomura K, Takahashi JS, Troy JB. Interpretation of the mouse electroretinogram. Documenta Ophthalmologica. Advances in Ophthalmology. 115: 127-36. PMID 17636411 DOI: 10.1007/s10633-007-9064-y  1
2007 McCarthy JJ, Andrews JL, McDearmon EL, Campbell KS, Barber BK, Miller BH, Walker JR, Hogenesch JB, Takahashi JS, Esser KA. Identification of the circadian transcriptome in adult mouse skeletal muscle. Physiological Genomics. 31: 86-95. PMID 17550994 DOI: 10.1152/physiolgenomics.00066.2007  0.92
2007 Liu AC, Welsh DK, Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED, Singer O, Meeker K, Verma IM, Doyle FJ, Takahashi JS, Kay SA. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell. 129: 605-16. PMID 17482552 DOI: 10.1016/j.cell.2007.02.047  1
2007 Siepka SM, Yoo SH, Park J, Song W, Kumar V, Hu Y, Lee C, Takahashi JS. Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell. 129: 1011-23. PMID 17462724 DOI: 10.1016/j.cell.2007.04.030  1
2007 Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Glawe B, Cantrell DR, Inayat S, Olvera MA, Vessey KA, McCall MA, ... ... Takahashi JS, et al. Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse. Visual Neuroscience. 24: 111-23. PMID 17430614 DOI: 10.1017/S0952523807070149  1
2007 McClurg P, Janes J, Wu C, Delano DL, Walker JR, Batalov S, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Wiltshire T, Su AI. Genomewide association analysis in diverse inbred mice: power and population structure. Genetics. 176: 675-83. PMID 17409088 DOI: 10.1534/genetics.106.066241  1
2007 Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA, et al. Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Sciences of the United States of America. 104: 6406-11. PMID 17379666 DOI: 10.1073/pnas.0609625104  1
2007 Miller BH, McDearmon EL, Panda S, Hayes KR, Zhang J, Andrews JL, Antoch MP, Walker JR, Esser KA, Hogenesch JB, Takahashi JS. Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 104: 3342-7. PMID 17360649 DOI: 10.1073/pnas.0611724104  0.96
2007 Hong HK, Chong JL, Song W, Song EJ, Jyawook AA, Schook AC, Ko CH, Takahashi JS. Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior. Plos Genetics. 3: e33. PMID 17319750 DOI: 10.1371/journal.pgen.0030033  1
2007 Kornmann B, Schaad O, Bujard H, Takahashi JS, Schibler U. System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. Plos Biology. 5: e34. PMID 17298173 DOI: 10.1371/journal.pbio.0050034  1
2007 Mignot E, Takahashi JS. A circadian sleep disorder reveals a complex clock. Cell. 128: 22-3. PMID 17218251 DOI: 10.1016/j.cell.2006.12.024  1
2007 Miller BH, McDearmon EL, Takahashi JS. The mammalian circadian system: From genes to behavior Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology. 801-834. DOI: 10.1007/978-0-387-30405-2_22  1
2006 McDearmon EL, Patel KN, Ko CH, Walisser JA, Schook AC, Chong JL, Wilsbacher LD, Song EJ, Hong HK, Bradfield CA, Takahashi JS. Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (New York, N.Y.). 314: 1304-8. PMID 17124323 DOI: 10.1126/science.1132430  1
2006 Ko CH, Takahashi JS. Molecular components of the mammalian circadian clock. Human Molecular Genetics. 15: R271-7. PMID 16987893 DOI: 10.1093/hmg/ddl207  1
2006 Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Takahashi JS, Churchill GA, Redei EE. Genetic analysis of the stress-responsive adrenocortical axis. Physiological Genomics. 27: 362-9. PMID 16895972 DOI: 10.1152/physiolgenomics.00052.2006  1
2006 Miller BH, Olson SL, Levine JE, Turek FW, Horton TH, Takahashi JS. Vasopressin regulation of the proestrous luteinizing hormone surge in wild-type and Clock mutant mice. Biology of Reproduction. 75: 778-84. PMID 16870944 DOI: 10.1095/biolreprod.106.052845  1
2006 Meredith AL, Wiler SW, Miller BH, Takahashi JS, Fodor AA, Ruby NF, Aldrich RW. BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nature Neuroscience. 9: 1041-9. PMID 16845385 DOI: 10.1038/nn1740  1
2006 Green CB, Takahashi JS. Xenobiotic metabolism in the fourth dimension: PARtners in time. Cell Metabolism. 4: 3-4. PMID 16814725 DOI: 10.1016/j.cmet.2006.06.002  1
2006 Vitaterna MH, Ko CH, Chang AM, Buhr ED, Fruechte EM, Schook A, Antoch MP, Turek FW, Takahashi JS. The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude. Proceedings of the National Academy of Sciences of the United States of America. 103: 9327-32. PMID 16754844 DOI: 10.1073/pnas.0603601103  1
2006 Vitaterna MH, Pinto LH, Takahashi JS. Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice. Trends in Neurosciences. 29: 233-40. PMID 16519954 DOI: 10.1016/j.tins.2006.02.006  1
2006 Baum AE, Solberg LC, Churchill GA, Ahmadiyeh N, Takahashi JS, Redei EE. Test- and behavior-specific genetic factors affect WKY hypoactivity in tests of emotionality. Behavioural Brain Research. 169: 220-30. PMID 16490266 DOI: 10.1016/j.bbr.2006.01.007  1
2006 Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, et al. Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Research. 16: 436-40. PMID 16461637 DOI: 10.1101/gr.4563306  1
2006 Buhr E, Takahashi JS. Genetic control of the circadian pacemaker The Genetic Basis of Sleep and Sleep Disorders. 119-126. DOI: 10.1017/CBO9781139649469.014  1
2005 Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, McDearmon EL, Fenner D, Lumayag SL, Omura C, Andrews AW, Baker M, Invergo BM, Olvera MA, Heffron E, Mullins RF, Sheffield VC, ... ... Takahashi JS, et al. Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse. Visual Neuroscience. 22: 619-29. PMID 16332273 DOI: 10.1017/S0952523805225117  1
2005 Brzezinski JA, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T. Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice. Investigative Ophthalmology & Visual Science. 46: 2540-51. PMID 15980246 DOI: 10.1167/iovs.04-1123  1
2005 McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ. Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 9377-81. PMID 15967985 DOI: 10.1073/pnas.0503584102  1
2005 Antoch MP, Kondratov RV, Takahashi JS. Circadian clock genes as modulators of sensitivity to genotoxic stress. Cell Cycle (Georgetown, Tex.). 4: 901-7. PMID 15917646 DOI: 10.1016/B978-012373947-6.00440-2  1
2005 Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, Eckel RH, Takahashi JS, Bass J. Obesity and metabolic syndrome in circadian Clock mutant mice. Science (New York, N.Y.). 308: 1043-5. PMID 15845877 DOI: 10.1126/science.1108750  1
2005 Low-Zeddies SS, Takahashi JS. Mouse chimeras and their application to circadian biology. Methods in Enzymology. 393: 478-92. PMID 15817307 DOI: 10.1016/S0076-6879(05)93024-3  1
2005 Yamazaki S, Takahashi JS. Real-time luminescence reporting of circadian gene expression in mammals. Methods in Enzymology. 393: 288-301. PMID 15817295 DOI: 10.1016/S0076-6879(05)93012-7  1
2005 Siepka SM, Takahashi JS. Methods to record circadian rhythm wheel running activity in mice. Methods in Enzymology. 393: 230-9. PMID 15817291 DOI: 10.1016/S0076-6879(05)93008-5  1
2005 Siepka SM, Takahashi JS. Forward genetic screens to identify circadian rhythm mutants in mice. Methods in Enzymology. 393: 219-29. PMID 15817290 DOI: 10.1016/S0076-6879(05)93007-3  1
2005 Yoo SH, Ko CH, Lowrey PL, Buhr ED, Song EJ, Chang S, Yoo OJ, Yamazaki S, Lee C, Takahashi JS. A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 2608-13. PMID 15699353 DOI: 10.1073/pnas.0409763102  1
2005 Gorbacheva VY, Kondratov RV, Zhang R, Cherukuri S, Gudkov AV, Takahashi JS, Antoch MP. Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex. Proceedings of the National Academy of Sciences of the United States of America. 102: 3407-12. PMID 15689397 DOI: 10.1073/pnas.0409897102  1
2005 Ahmadiyeh N, Churchill GA, Solberg LC, Baum AE, Shimomura K, Takahashi JS, Redei EE. Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behavior Genetics. 35: 189-98. PMID 15685431 DOI: 10.1007/s10519-004-1018-5  1
2005 Prolo LM, Takahashi JS, Herzog ED. Circadian rhythm generation and entrainment in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 404-8. PMID 15647483 DOI: 10.1523/JNEUROSCI.4133-04.2005  1
2005 Baum AE, Solberg LC, Kopp P, Ahmadiyeh N, Churchill G, Takahashi JS, Jameson JL, Redei EE. Quantitative trait loci associated with elevated thyroid-stimulating hormone in the Wistar-Kyoto rat. Endocrinology. 146: 870-8. PMID 15514085 DOI: 10.1210/en.2004-0948  1
2004 Welsh DK, Yoo SH, Liu AC, Takahashi JS, Kay SA. Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Current Biology : Cb. 14: 2289-95. PMID 15620658 DOI: 10.1016/j.cub.2004.11.057  1
2004 Clark AT, Goldowitz D, Takahashi JS, Vitaterna MH, Siepka SM, Peters LL, Frankel WN, Carlson GA, Rossant J, Nadeau JH, Justice MJ. Implementing large-scale ENU mutagenesis screens in North America. Genetica. 122: 51-64. PMID 15619961 DOI: 10.1007/s10709-004-1436-6  1
2004 Triqueneaux G, Thenot S, Kakizawa T, Antoch MP, Safi R, Takahashi JS, Delaunay F, Laudet V. The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker. Journal of Molecular Endocrinology. 33: 585-608. PMID 15591021 DOI: 10.1677/jme.1.01554  1
2004 Goldowitz D, Frankel WN, Takahashi JS, Holtz-Vitaterna M, Bult C, Kibbe WA, Snoddy J, Li Y, Pretel S, Yates J, Swanson DJ. Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function. Brain Research. Molecular Brain Research. 132: 105-15. PMID 15582151 DOI: 10.1016/j.molbrainres.2004.09.016  1
2004 Takahashi JS. Finding new clock components: past and future. Journal of Biological Rhythms. 19: 339-47. PMID 15536063 DOI: 10.1177/0748730404269151  1
2004 Pinto LH, Vitaterna MH, Siepka SM, Shimomura K, Lumayag S, Baker M, Fenner D, Mullins RF, Sheffield VC, Stone EM, Heffron E, Takahashi JS. Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus. Vision Research. 44: 3335-45. PMID 15536001 DOI: 10.1016/j.visres.2004.07.025  1
2004 Lowrey PL, Takahashi JS. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annual Review of Genomics and Human Genetics. 5: 407-41. PMID 15485355 DOI: 10.1146/annurev.genom.5.061903.175925  1
2004 Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Churchill GA, Takahashi JS, Redei EE. Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 648-62. PMID 15457344 DOI: 10.1007/s00335-004-2326-z  1
2004 Miller BH, Olson SL, Turek FW, Levine JE, Horton TH, Takahashi JS. Circadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy. Current Biology : Cb. 14: 1367-73. PMID 15296754 DOI: 10.1016/j.cub.2004.07.055  1
2004 Ahmadiyeh N, Slone-Wilcoxon JL, Takahashi JS, Redei EE. Maternal behavior modulates X-linked inheritance of behavioral coping in the defensive burying test. Biological Psychiatry. 55: 1069-74. PMID 15158425 DOI: 10.1016/j.biopsych.2004.02.014  1
2004 Bult C, Kibbe WA, Snoddy J, Vitaterna M, Swanson D, Pretel S, Li Y, Hohman MM, Rinchik E, Takahashi JS, Frankel WN, Goldowitz D. A genome end-game: understanding gene function in the nervous system. Nature Neuroscience. 7: 484-5. PMID 15114363 DOI: 10.1038/nn0504-484  1
2004 Kolker DE, Vitaterna MH, Fruechte EM, Takahashi JS, Turek FW. Effects of age on circadian rhythms are similar in wild-type and heterozygous Clock mutant mice. Neurobiology of Aging. 25: 517-23. PMID 15013573 DOI: 10.1016/j.neurobiolaging.2003.06.007  1
2004 Yoo SH, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, Buhr ED, Siepka SM, Hong HK, Oh WJ, Yoo OJ, Menaker M, Takahashi JS. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proceedings of the National Academy of Sciences of the United States of America. 101: 5339-46. PMID 14963227 DOI: 10.1073/pnas.0308709101  1
2004 Hong HK, Chakravarti A, Takahashi JS. The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 1748-53. PMID 14755058 DOI: 10.1073/pnas.0308268100  1
2003 Ahmadiyeh N, Churchill GA, Shimomura K, Solberg LC, Takahashi JS, Redei EE. X-linked and lineage-dependent inheritance of coping responses to stress. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 748-57. PMID 14722724 DOI: 10.1007/s00335-003-2292-x  1
2003 Hogenesch JB, Panda S, Kay S, Takahashi JS. Circadian transcriptional output in the SCN and liver of the mouse. Novartis Foundation Symposium. 253: 171-80; discussion 5. PMID 14712921  0.92
2003 Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR. Time- and exercise-dependent gene regulation in human skeletal muscle. Genome Biology. 4: R61. PMID 14519196 DOI: 10.1186/gb-2003-4-10-r61  1
2003 Solberg LC, Ahmadiyeh N, Baum AE, Vitaterna MH, Takahashi JS, Turek FW, Redei EE. Depressive-like behavior and stress reactivity are independent traits in a Wistar Kyoto x Fisher 344 cross. Molecular Psychiatry. 8: 423-33. PMID 12740600 DOI: 10.1038/sj.mp.4001255  1
2003 Kolker DE, Fukuyama H, Huang DS, Takahashi JS, Horton TH, Turek FW. Aging alters circadian and light-induced expression of clock genes in golden hamsters. Journal of Biological Rhythms. 18: 159-69. PMID 12693870 DOI: 10.1177/0748730403251802  1
2002 Rosbash M, Takahashi JS. Circadian rhythms: the cancer connection. Nature. 420: 373-4. PMID 12459770 DOI: 10.1038/420373a  1
2002 Merikangas KR, Chakravarti A, Moldin SO, Araj H, Blangero JC, Burmeister M, Crabbe J, Depaulo JR, Foulks E, Freimer NB, Koretz DS, Lichtenstein W, Mignot E, Reiss AL, Risch NJ, ... Takahashi JS, et al. Future of genetics of mood disorders research. Biological Psychiatry. 52: 457-77. PMID 12361664 DOI: 10.1016/S0006-3223(02)01471-3  1
2002 Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell. 109: 307-20. PMID 12015981 DOI: 10.1016/S0092-8674(02)00722-5  1
2002 Wilsbacher LD, Yamazaki S, Herzog ED, Song EJ, Radcliffe LA, Abe M, Block G, Spitznagel E, Menaker M, Takahashi JS. Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice invivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 489-94. PMID 11752392 DOI: 10.1073/pnas.012248599  1
2001 Vitaterna MH, Takahashi JS, Turek FW. Overview of circadian rhythms. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 25: 85-93. PMID 11584554  1
2001 Allada R, Emery P, Takahashi JS, Rosbash M. Stopping time: the genetics of fly and mouse circadian clocks. Annual Review of Neuroscience. 24: 1091-119. PMID 11520929 DOI: 10.1146/annurev.neuro.24.1.1091  1
2001 Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC. Familial advanced sleep phase syndrome. Archives of Neurology. 58: 1089-94. PMID 11448298  1
2001 Shimomura K, Low-Zeddies SS, King DP, Steeves TD, Whiteley A, Kushla J, Zemenides PD, Lin A, Vitaterna MH, Churchill GA, Takahashi JS. Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice. Genome Research. 11: 959-80. PMID 11381025 DOI: 10.1101/gr.171601  1
2001 Low-Zeddies SS, Takahashi JS. Chimera analysis of the Clock mutation in mice shows that complex cellular integration determines circadian behavior. Cell. 105: 25-42. PMID 11301000 DOI: 10.1016/S0092-8674(01)00294-X  1
2001 Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M, Camper S, Carlson G, Copeland N, Eppig J, Fletcher C, Frankel WN, Ganten D, Goldowitz D, Goodnow C, ... ... Takahashi JS, et al. Sequence interpretation. Functional annotation of mouse genome sequences. Science (New York, N.Y.). 291: 1251-5. PMID 11233449 DOI: 10.1126/science.1058244  1
2001 Valentinuzzi VS, Kolker DE, Vitaterna MH, Ferrari EAM, Takahashi JS, Turek FW. Effect of circadian phase on context and cued fear conditioning in C57BL/6J mice Animal Learning and Behavior. 29: 133-142.  1
2000 Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 103: 1009-17. PMID 11163178 DOI: 10.1016/S0092-8674(00)00205-1  1
2000 Wilsbacher LD, Sangoram AM, Antoch MP, Takahashi JS. The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5. Genome Research. 10: 1928-40. PMID 11116088 DOI: 10.1101/gr.10.12.1928  1
2000 Lowrey PL, Takahashi JS. Genetics of the mammalian circadian system: Photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation. Annual Review of Genetics. 34: 533-562. PMID 11092838 DOI: 10.1146/annurev.genet.34.1.533  1
2000 Naylor E, Bergmann BM, Krauski K, Zee PC, Takahashi JS, Vitaterna MH, Turek FW. The circadian clock mutation alters sleep homeostasis in the mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8138-43. PMID 11050136  1
2000 Valentinuzzi VS, Buxton OM, Chang AM, Scarbrough K, Ferrari EA, Takahashi JS, Turek FW. Locomotor response to an open field during C57BL/6J active and inactive phases: differences dependent on conditions of illumination. Physiology & Behavior. 69: 269-75. PMID 10869592 DOI: 10.1016/S0031-9384(00)00219-5  1
2000 Hogenesch JB, Gu YZ, Moran SM, Shimomura K, Radcliffe LA, Takahashi JS, Bradfield CA. The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC83. PMID 10864977  1
2000 King DP, Takahashi JS. Molecular genetics of circadian rhythms in mammals. Annual Review of Neuroscience. 23: 713-42. PMID 10845079 DOI: 10.1146/annurev.neuro.23.1.713  1
2000 Lowrey PL, Shimomura K, Antoch MP, Yamazaki S, Zemenides PD, Ralph MR, Menaker M, Takahashi JS. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science (New York, N.Y.). 288: 483-92. PMID 10775102 DOI: 10.1126/science.288.5465.483  1
2000 Challet E, Takahashi JS, Turek FW. Nonphotic phase-shifting in clock mutant mice. Brain Research. 859: 398-403. PMID 10719095 DOI: 10.1016/S0006-8993(00)02040-0  1
2000 Zhu H, LaRue S, Whiteley A, Steeves TD, Takahashi JS, Green CB. The Xenopus clock gene is constitutively expressed in retinal photoreceptors. Brain Research. Molecular Brain Research. 75: 303-8. PMID 10686352 DOI: 10.1016/S0169-328X(99)00309-5  1
1999 Nelson DE, Takahashi JS. Integration and saturation within the circadian photic entrainment pathway of hamsters. The American Journal of Physiology. 277: R1351-61. PMID 10564207  1
1999 Takahashi JS. Narcolepsy genes wake up the sleep field. Science (New York, N.Y.). 285: 2076-7. PMID 10523205 DOI: 10.1126/science.285.5436.2076  1
1999 Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, Takahashi JS, Sancar A. Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proceedings of the National Academy of Sciences of the United States of America. 96: 12114-9. PMID 10518585 DOI: 10.1073/pnas.96.21.12114  1
1999 Hahm S, Mizuno TM, Wu TJ, Wisor JP, Priest CA, Kozak CA, Boozer CN, Peng B, McEvoy RC, Good P, Kelley KA, Takahashi JS, Pintar JE, Roberts JL, Mobbs CV, et al. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron. 23: 537-48. PMID 10433265 DOI: 10.1016/S0896-6273(00)80806-5  1
1999 Steeves TD, King DP, Zhao Y, Sangoram AM, Du F, Bowcock AM, Moore RY, Takahashi JS. Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei. Genomics. 57: 189-200. PMID 10198158 DOI: 10.1006/geno.1998.5675  1
1999 Pinto LH, Takahashi JS. Chapter 2.1.7 Genetic dissection of mouse behavior using induced mutagenesis Techniques in the Behavioral and Neural Sciences. 13: 147-165. DOI: 10.1016/S0921-0709(99)80015-7  1
1998 Valentinuzzi VS, Kolker DE, Vitaterna MH, Shimomura K, Whiteley A, Low-Zeddies S, Turek FW, Ferrari EA, Paylor R, Takahashi JS. Automated measurement of mouse freezing behavior and its use for quantitative trait locus analysis of contextual fear conditioning in (BALB/cJ x C57BL/6J)F2 mice. Learning & Memory (Cold Spring Harbor, N.Y.). 5: 391-403. PMID 10454363  1
1998 Herzog ED, Takahashi JS, Block GD. Clock controls circadian period in isolated suprachiasmatic nucleus neurons. Nature Neuroscience. 1: 708-13. PMID 10196587 DOI: 10.1038/3708  1
1998 Zhang Y, Brainard GC, Zee PC, Pinto LH, Takahashi JS, Turek FW. Effects of aging on lens transmittance and retinal input to the suprachiasmatic nucleus in golden hamsters. Neuroscience Letters. 258: 167-70. PMID 9885957 DOI: 10.1016/S0304-3940(98)00887-8  1
1998 Sangoram AM, Saez L, Antoch MP, Gekakis N, Staknis D, Whiteley A, Fruechte EM, Vitaterna MH, Shimomura K, King DP, Young MW, Weitz CJ, Takahashi JS. Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription. Neuron. 21: 1101-13. PMID 9856465 DOI: 10.1016/S0896-6273(00)80627-3  1
1998 Nikaido SS, Takahashi JS. Day/night differences in the stimulation of adenylate cyclase activity by calcium/calmodulin in chick pineal cell cultures: evidence for circadian regulation of cyclic AMP. Journal of Biological Rhythms. 13: 479-93. PMID 9850009  1
1998 Thresher RJ, Vitaterna MH, Miyamoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L, Smithies O, Takahashi JS, Sancar A. Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science (New York, N.Y.). 282: 1490-4. PMID 9822380  1
1998 Wilsbacher LD, Takahashi JS. Circadian rhythms: molecular basis of the clock. Current Opinion in Genetics & Development. 8: 595-602. PMID 9794822 DOI: 10.1016/S0959-437X(98)80017-8  1
1998 Katzenberg D, Young T, Finn L, Lin L, King DP, Takahashi JS, Mignot E. A CLOCK polymorphism associated with human diurnal preference. Sleep. 21: 569-76. PMID 9779516  1
1998 Max M, Surya A, Takahashi JS, Margolskee RF, Knox BE. Light-dependent activation of rod transducin by pineal opsin. The Journal of Biological Chemistry. 273: 26820-6. PMID 9756926 DOI: 10.1074/jbc.273.41.26820  1
1998 Shimomura K, Kornhauser JM, Wisor JP, Umezu T, Yamazaki S, Ihara NL, Takahashi JS, Menaker M. Circadian behavior and plasticity of light-induced c-fos expression in SCN of tau mutant hamsters. Journal of Biological Rhythms. 13: 305-14. PMID 9711506  1
1998 Darlington TK, Wager-Smith K, Ceriani MF, Staknis D, Gekakis N, Steeves TD, Weitz CJ, Takahashi JS, Kay SA. Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. Science (New York, N.Y.). 280: 1599-603. PMID 9616122 DOI: 10.1126/science.280.5369.1599  1
1998 Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, Weitz CJ. Role of the CLOCK protein in the mammalian circadian mechanism. Science (New York, N.Y.). 280: 1564-9. PMID 9616112 DOI: 10.1126/science.280.5369.1564  1
1997 Valentinuzzi VS, Scarbrough K, Takahashi JS, Turek FW. Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 273: R1957-R1964. PMID 29586946 DOI: 10.1152/ajpregu.1997.273.6.R1957  1
1997 Barrett RK, Takahashi JS. Lability of circadian pacemaker amplitude in chick pineal cells: a temperature-dependent process. Journal of Biological Rhythms. 12: 309-18. PMID 9438879  1
1997 Valentinuzzi VS, Scarbrough K, Takahashi JS, Turek FW. Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice. The American Journal of Physiology. 273: R1957-64. PMID 9435649  1
1997 Silva AJ, Simpson EM, Takahashi JS, Lipp HP, Nakanishi S, Wehner JM, Giese KP, Tully T, Abel T, Chapman PF, Fox K, Grant S, Itohara S, Lathe R, Mayford M, et al. Mutant mice and neuroscience: Recommendations concerning genetic background Neuron. 19: 755-759. PMID 9354323 DOI: 10.1016/S0896-6273(00)80958-7  1
1997 King DP, Vitaterna MH, Chang AM, Dove WF, Pinto LH, Turek FW, Takahashi JS. The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit. Genetics. 146: 1049-60. PMID 9215907  1
1997 Lin JT, Kornhauser JM, Singh NP, Mayo KE, Takahashi JS. Visual sensitivities of nur77 (NGFI-B) and zif268 (NGFI-A) induction in the suprachiasmatic nucleus are dissociated from c-fos induction and behavioral phase-shifting responses. Brain Research. Molecular Brain Research. 46: 303-10. PMID 9191106 DOI: 10.1016/S0169-328X(97)00005-3  1
1997 Antoch MP, Song EJ, Chang AM, Vitaterna MH, Zhao Y, Wilsbacher LD, Sangoram AM, King DP, Pinto LH, Takahashi JS. Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell. 89: 655-67. PMID 9160756  1
1997 King DP, Zhao Y, Sangoram AM, Wilsbacher LD, Tanaka M, Antoch MP, Steeves TD, Vitaterna MH, Kornhauser JM, Lowrey PL, Turek FW, Takahashi JS. Positional cloning of the mouse circadian clock gene. Cell. 89: 641-53. PMID 9160755  1
1997 Wisor JP, Takahashi JS. Regulation of the vgf gene in the golden hamster suprachiasmatic nucleus by light and by the circadian clock. The Journal of Comparative Neurology. 378: 229-38. PMID 9120062 DOI: 10.1002/(SICI)1096-9861(19970210)378:2<229::AID-CNE6>3.0.CO;2-5  1
1996 King DP, Takahashi JS. Forward genetic approaches to circadian clocks in mice. Cold Spring Harbor Symposia On Quantitative Biology. 61: 295-302. PMID 9246458  1
1996 Kornhauser JM, Ginty DD, Greenberg ME, Mayo KE, Takahashi JS. Light entrainment and activation of signal transduction pathways in the SCN. Progress in Brain Research. 111: 133-46. PMID 8990912  1
1996 Takahashi JS. The biological clock: it's all in the genes. Progress in Brain Research. 111: 5-9. PMID 8990903  1
1996 Zhang Y, Takahashi JS, Turek FW. Critical period for cycloheximide blockade of light-induced phase advances of the circadian locomotor activity rhythm in golden hamsters. Brain Research. 740: 285-90. PMID 8973826 DOI: 10.1016/S0006-8993(96)00900-6  1
1996 Florez JC, Seidenman KJ, Barrett RK, Sangoram AM, Takahashi JS. Molecular cloning of chick pineal tryptophan hydroxylase and circadian oscillation of its mRNA levels. Brain Research. Molecular Brain Research. 42: 25-30. PMID 8915576 DOI: 10.1016/S0169-328X(96)00104-0  1
1996 Florez JC, Takahashi JS. Quantitative two-dimensional gel electrophoretic analysis of clock-controlled proteins in cultured chick pineal cells: circadian regulation of tryptophan hydroxylase. Journal of Biological Rhythms. 11: 241-57. PMID 8872596  1
1996 Zhang Y, Kornhauser JM, Zee PC, Mayo KE, Takahashi JS, Turek FW. Effects of aging on light-induced phase-shifting of circadian behavioral rhythms, fos expression and CREB phosphorylation in the hamster suprachiasmatic nucleus. Neuroscience. 70: 951-61. PMID 8848176 DOI: 10.1016/0306-4522(95)00408-4  1
1996 Kornhauser JM, Mayo KE, Takahashi JS. Light, immediate-early genes, and circadian rhythms. Behavior Genetics. 26: 221-40. PMID 8754249 DOI: 10.1007/BF02359382  1
1996 Nikaido SS, Takahashi JS. Calcium modulates circadian variation in cAMP-stimulated melatonin in chick pineal cells. Brain Research. 716: 1-10. PMID 8738214 DOI: 10.1016/0006-8993(95)01521-3  1
1996 Takahashi JS. Circadian rhythms. Ion channels get the message. Nature. 382: 117-8. PMID 8700199 DOI: 10.1038/382117a0  1
1996 Florez JC, Takahashi JS. Regulation of tryptophan hydroxylase by cyclic AMP, calcium, norepinephrine, and light in cultured chick pineal cells. Journal of Neurochemistry. 67: 242-50. PMID 8666997  1
1996 Max M, Surya A, Takahashi JS, Margolskee RF, Knox BE. Light-dependent activation of transducin by pineal opsin Investigative Ophthalmology and Visual Science. 37: S811.  1
1995 Florez JC, Takahashi JS. The circadian clock: from molecules to behaviour. Annals of Medicine. 27: 481-90. PMID 8519510 DOI: 10.3109/07853899709002457  1
1995 Max M, McKinnon PJ, Seidenman KJ, Barrett RK, Applebury ML, Takahashi JS, Margolskee RF. Pineal opsin: a nonvisual opsin expressed in chick pineal. Science (New York, N.Y.). 267: 1502-6. PMID 7878470  1
1995 Janavs JL, Florez JC, Pierce ME, Takahashi JS. Forskolin and camptothecin induce a 30 kDa protein associated with melatonin production in Y79 human retinoblastoma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 298-309. PMID 7823135  1
1995 Turek FW, Penev P, Zhang Y, Van Reeth O, Takahashi JS, Zee P. Alterations in the circadian system in advanced age. Ciba Foundation Symposium. 183: 212-26; discussion 2. PMID 7656687  1
1995 Barrett RK, Takahashi JS. Temperature compensation and temperature entrainment of the chick pineal cell circadian clock. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5681-92. PMID 7643210  1
1995 Takahashi JS. Molecular neurobiology and genetics of circadian rhythms in mammals. Annual Review of Neuroscience. 18: 531-53. PMID 7605073 DOI: 10.1146/annurev.ne.18.030195.002531  1
1995 Turek FW, Pinto LH, Vitaterna MH, Penev PD, Zee PC, Takahashi JS. Pharmacological and genetic approaches for the study of circadian rhythms in mammals. Frontiers in Neuroendocrinology. 16: 191-223. PMID 7556850 DOI: 10.1006/frne.1995.1007  1
1995 Menaker M, Takahashi JS. Genetic analysis of the circadian system of mammals: properties and prospects Seminars in Neuroscience. 7: 61-70. DOI: 10.1016/1044-5765(95)90018-7  1
1995 Takahashi JS, Hoffman M. Molecular biological clocks American Scientist. 83: 158-165.  1
1994 Takahashi JS, Pinto LH, Vitaterna MH. Forward and reverse genetic approaches to behavior in the mouse. Science (New York, N.Y.). 264: 1724-33. PMID 8209253  1
1994 Vitaterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW, Takahashi JS. Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science (New York, N.Y.). 264: 719-25. PMID 8171325  1
1994 Janavs JL, Pierce ME, Takahashi JS. RNA synthesis inhibitors increase melatonin production in Y79 human retinoblastoma cells. Brain Research. Molecular Brain Research. 23: 47-56. PMID 8028483 DOI: 10.1016/0169-328X(94)90210-0  1
1994 Takahashi JS. Circadian rhythms. ICER is nicer at night (sir!). Current Biology : Cb. 4: 165-8. PMID 7953523 DOI: 10.1016/S0960-9822(94)00040-0  1
1994 Besecke LM, Wolfe AM, Pierce ME, Takahashi JS, Levine JE. Neuropeptide Y stimulates luteinizing hormone-releasing hormone release from superfused hypothalamic GT1-7 cells. Endocrinology. 135: 1621-7. PMID 7925125 DOI: 10.1210/endo.135.4.7925125  1
1994 Sheshberadaran H, Takahashi JS. Characterization of the chicken rhodopsin promoter: identification of retina-specific and glass-like protein binding domains. Molecular and Cellular Neurosciences. 5: 309-18. PMID 7804600 DOI: 10.1006/mcne.1994.1037  1
1993 Pierce ME, Sheshberadaran H, Zhang Z, Fox LE, Applebury ML, Takahashi JS. Circadian regulation of iodopsin gene expression in embryonic photoreceptors in retinal cell culture. Neuron. 10: 579-84. PMID 8476610 DOI: 10.1016/0896-6273(93)90161-J  1
1993 Takahashi JS, Kornhauser JM, Koumenis C, Eskin A. Molecular approaches to understanding circadian oscillations. Annual Review of Physiology. 55: 729-53. PMID 8466190 DOI: 10.1146/annurev.ph.55.030193.003501  1
1993 Takahashi JS. Gene regulation. Circadian clocks à la CREM. Nature. 365: 299-300. PMID 8397337 DOI: 10.1038/365299a0  1
1993 Zhang Y, Zee PC, Kirby JD, Takahashi JS, Turek FW. A cholinergic antagonist, mecamylamine, blocks light-induced fos immunoreactivity in specific regions of the hamster suprachiasmatic nucleus. Brain Research. 615: 107-12. PMID 8364719 DOI: 10.1016/0006-8993(93)91120-H  1
1993 Zhang Y, Van Reeth O, Zee PC, Takahashi JS, Turek FW. Fos protein expression in the circadian clock is not associated with phase shifts induced by a nonphotic stimulus, triazolam. Neuroscience Letters. 164: 203-8. PMID 8152601 DOI: 10.1016/0304-3940(93)90892-O  1
1993 Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science (New York, N.Y.). 260: 238-41. PMID 8097062  1
1992 Smith RD, Turek FW, Takahashi JS. Two families of phase-response curves characterize the resetting of the hamster circadian clock. The American Journal of Physiology. 262: R1149-53. PMID 1621870  1
1992 Kornhauser JM, Nelson DE, Mayo KE, Takahashi JS. Regulation of jun-B messenger RNA and AP-1 activity by light and a circadian clock. Science (New York, N.Y.). 255: 1581-4. PMID 1549784  1
1991 Janavs JL, Pierce ME, Takahashi JS. N-acetyltransferase and protein synthesis modulate melatonin production by Y79 human retinoblastoma cells. Brain Research. 540: 138-44. PMID 2054606 DOI: 10.1016/0006-8993(91)90500-U  1
1991 Nelson DE, Takahashi JS. Comparison of visual sensitivity for suppression of pineal melatonin and circadian phase-shifting in the golden hamster. Brain Research. 554: 272-7. PMID 1933309 DOI: 10.1016/0006-8993(91)90200-F  1
1991 Nelson DE, Takahashi JS. Sensitivity and integration in a visual pathway for circadian entrainment in the hamster (Mesocricetus auratus). The Journal of Physiology. 439: 115-45. PMID 1895235  1
1990 Kornhauser JM, Nelson DE, Mayo KE, Takahashi JS. Photic and circadian regulation of c-fos gene expression in the hamster suprachiasmatic nucleus. Neuron. 5: 127-34. PMID 2116813 DOI: 10.1016/0896-6273(90)90303-W  1
1990 Milette JJ, Takahashi JS, Turek FW. Photic threshold for stimulation of testicular growth and pituitary FSH release in male Djungarian hamsters. Brain Research. 512: 304-8. PMID 2112972 DOI: 10.1016/0006-8993(90)90641-N  1
1989 Takahashi JS, Nelson DE, Eskin A. Immunocytochemical localization of serotonergic fibers innervating the ocular circadian system of Aplysia. Neuroscience. 28: 139-47. PMID 2761688 DOI: 10.1016/0306-4522(89)90238-8  1
1989 Duncan MJ, Takahashi JS, Dubocovich ML. Characteristics and autoradiographic localization of 2-[125I]iodomelatonin binding sites in Djungarian hamster brain. Endocrinology. 125: 1011-8. PMID 2752961 DOI: 10.1210/endo-125-2-1011  0.64
1989 Takahashi JS, Murakami N, Nikaido SS, Pratt BL, Robertson LM. The avian pineal, a vertebrate model system of the circadian oscillator: cellular regulation of circadian rhythms by light, second messengers, and macromolecular synthesis. Recent Progress in Hormone Research. 45: 279-348; discussion . PMID 2682842  1
1989 Wollnik F, Turek FW, Majewski P, Takahashi JS. Phase shifting the circadian clock with cycloheximide: response of hamsters with an intact or a split rhythm of locomotor activity. Brain Research. 496: 82-8. PMID 2679970  1
1989 Hamm HE, Deretic D, Mazzoni MR, Moore CA, Takahashi JS, Rasenick MM. A monoclonal antibody against the rod outer segment guanyl nucleotide-binding protein, transducin, blocks the stimulatory and inhibitory G proteins of adenylate cyclase. The Journal of Biological Chemistry. 264: 11475-82. PMID 2544596  1
1989 Nikaido SS, Takahashi JS. Twenty-four hour oscillation of cAMP in chick pineal cells: role of cAMP in the acute and circadian regulation of melatonin production. Neuron. 3: 609-19. PMID 2484343 DOI: 10.1016/0896-6273(89)90271-7  1
1989 Pratt BL, Takahashi JS. Vasoactive intestinal polypeptide and alpha 2-adrenoceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures. Endocrinology. 125: 2375-84. PMID 2477231 DOI: 10.1210/endo-125-5-2375  1
1989 Pierce ME, Barker D, Harrington J, Takahashi JS. Cyclic AMP-dependent melatonin production in Y79 human retinoblastoma cells. Journal of Neurochemistry. 53: 307-10. PMID 2470863  1
1988 Robertson LM, Takahashi JS. Circadian clock in cell culture: II. In vitro photic entrainment of melatonin oscillation from dissociated chick pineal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 22-30. PMID 3339410  1
1988 Robertson LM, Takahashi JS. Circadian clock in cell culture: I. Oscillation of melatonin release from dissociated chick pineal cells in flow-through microcarrier culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 12-21. PMID 3276829  1
1988 Inouye ST, Takahashi JS, Wollnik F, Turek FW. Inhibitor of protein synthesis phase shifts a circadian pacemaker in mammalian SCN. The American Journal of Physiology. 255: R1055-8. PMID 3202220  1
1988 Pratt BL, Takahashi JS. A pertussis toxin-sensitive G-protein mediates the alpha 2-adrenergic receptor inhibition of melatonin release in photoreceptive chick pineal cell cultures. Endocrinology. 123: 277-83. PMID 2838256 DOI: 10.1210/endo-123-1-277  1
1988 Duncan MJ, Takahashi JS, Dubocovich ML. 2-[125I]iodomelatonin binding sites in hamster brain membranes: pharmacological characteristics and regional distribution. Endocrinology. 122: 1825-33. PMID 2834175 DOI: 10.1210/endo-122-5-1825  0.64
1987 Takahashi JS, Turek FW. Anisomycin, an inhibitor of protein synthesis, perturbs the phase of a mammalian circadian pacemaker. Brain Research. 405: 199-203. PMID 3567595  1
1987 Keefe DL, Earnest DJ, Nelson D, Takahashi JS, Turek FW. A cholinergic antagonist, mecamylamine, blocks the phase-shifting effects of light on the circadian rhythm of locomotor activity in the golden hamster. Brain Research. 403: 308-12. PMID 3548889 DOI: 10.1016/0006-8993(87)90068-0  1
1987 Dubocovich ML, Takahashi JS. Use of 2-[125I]iodomelatonin to characterize melatonin binding sites in chicken retina. Proceedings of the National Academy of Sciences of the United States of America. 84: 3916-20. PMID 3035559  0.64
1987 Pratt BL, Takahashi JS. Alpha-2 adrenergic regulation of melatonin release in chick pineal cell cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3665-74. PMID 2890722  1
1986 Duncan MJ, Takahashi JS, Dubocovich ML. Characterization of 2-[125I]iodomelatonin binding sites in hamster brain. European Journal of Pharmacology. 132: 333-4. PMID 3816982  0.64
1986 Cassone VM, Takahashi JS, Blaha CD, Lane RF, Menaker M. Dynamics of noradrenergic circadian input to the chicken pineal gland. Brain Research. 384: 334-41. PMID 3779384 DOI: 10.1016/0006-8993(86)91169-8  1
1985 Dubocovich ML, Lucas RC, Takahashi JS. Light-dependent regulation of dopamine receptors in mammalian retina. Brain Research. 335: 321-5. PMID 2988696  0.64
1984 Takahashi JS, DeCoursey PJ, Bauman L, Menaker M. Spectral sensitivity of a novel photoreceptive system mediating entrainment of mammalian circadian rhythms. Nature. 308: 186-8. PMID 6700721 DOI: 10.1038/308186a0  1
1984 Eskin A, Takahashi JS, Zatz M, Block GD. Cyclic guanosine 3':5'-monophosphate mimics the effects of light on a circadian pacemaker in the eye of aplysia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2466-71. PMID 6092562  1
1983 Hamm HE, Takahashi JS, Menaker M. Light-induced decrease of serotonin N-acetyltransferase activity and melatonin in the chicken pineal gland and retina. Brain Research. 266: 287-93. PMID 6871664 DOI: 10.1016/0006-8993(83)90660-1  1
1983 Eskin A, Takahashi JS. Adenylate cyclase activation shifts the phase of a circadian pacemaker. Science (New York, N.Y.). 220: 82-4. PMID 6298939  1
1982 Takahashi JS, Menaker M. Role of the suprachiasmatic nuclei in the circadian system of the house sparrow, Passer domesticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 815-28. PMID 7086486  1
1982 Takahashi JS, Zatz M. Regulation of circadian rhythmicity. Science (New York, N.Y.). 217: 1104-11. PMID 6287576  1
1980 Takahashi JS, Menaker M. Interaction of estradiol and progesterone: effects on circadian locomotor rhythm of female golden hamsters. The American Journal of Physiology. 239: R497-504. PMID 7192057  1
1980 Takahashi JS, Hamm H, Menaker M. Circadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro. Proceedings of the National Academy of Sciences of the United States of America. 77: 2319-22. PMID 6929552  1
1979 Takahashi JS, Menaker M. Physiology of avian circadian pacemakers. Federation Proceedings. 38: 2583-8. PMID 499574  1
1978 Menaker M, Takahashi JS, Eskin A. The physiology of circadian pacemakers. Annual Review of Physiology. 40: 501-26. PMID 345954 DOI: 10.1146/annurev.ph.40.030178.002441  1
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