Marzia Malcangio - Publications

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68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T, Grist J, Al-Ahdal H, Wong LF, Perretti M, Lai J, Mouritzen P, Heppenstall P, ... Malcangio M, et al. Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. Nature Communications. 8: 1778. PMID 29176651 DOI: 10.1038/s41467-017-01841-5  0.64
2016 Nieto FR, Clark AK, Grist J, Hathway GJ, Chapman V, Malcangio M. Neuron-immune mechanisms contribute to pain in early stages of arthritis. Journal of Neuroinflammation. 13: 96. PMID 27130316 DOI: 10.1186/s12974-016-0556-0  0.92
2016 Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner. Arthritis Research & Therapy. 18: 7. PMID 26754745 DOI: 10.1186/s13075-015-0905-x  0.92
2015 Hansen RR, Vacca V, Pitcher T, Clark AK, Malcangio M. Role of extracellular calcitonin gene-related peptide in spinal cord mechanisms of cancer-induced bone pain. Pain. PMID 26574822 DOI: 10.1097/j.pain.0000000000000416  0.64
2015 Nicol LS, Dawes JM, La Russa F, Didangelos A, Clark AK, Gentry C, Grist J, Davies JB, Malcangio M, McMahon SB. The Role of G-Protein Receptor 84 in Experimental Neuropathic Pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8959-69. PMID 26063927 DOI: 10.1523/JNEUROSCI.3558-14.2015  0.92
2015 Ogbonna AC, Clark AK, Malcangio M. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. Age (Dordrecht, Netherlands). 37: 9792. PMID 25971876 DOI: 10.1007/s11357-015-9792-y  0.64
2015 Luongo L, Malcangio M, Salvemini D, Starowicz K. Chronic pain: new insights in molecular and cellular mechanisms. Biomed Research International. 2015: 676725. PMID 25879035 DOI: 10.1155/2015/676725  0.92
2015 Old EA, Clark AK, Malcangio M. The role of glia in the spinal cord in neuropathic and inflammatory pain. Handbook of Experimental Pharmacology. 227: 145-70. PMID 25846618 DOI: 10.1007/978-3-662-46450-2_8  0.64
2015 Clark AK, Gruber-Schoffnegger D, Drdla-Schutting R, Gerhold KJ, Malcangio M, Sandkühler J. Selective activation of microglia facilitates synaptic strength. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4552-70. PMID 25788673 DOI: 10.1523/JNEUROSCI.2061-14.2015  0.92
2015 Nieto FR, Clark AK, Grist J, Chapman V, Malcangio M. Calcitonin gene-related Peptide-expressing sensory neurons and spinal microglial reactivity contribute to pain States in collagen-induced arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1668-77. PMID 25707377 DOI: 10.1002/art.39082  0.92
2014 Clark AK, Malcangio M. Fractalkine/CX3CR1 signaling during neuropathic pain. Frontiers in Cellular Neuroscience. 8: 121. PMID 24847207 DOI: 10.3389/fncel.2014.00121  0.64
2014 Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim KW, Mogg AJ, Perretti M, Malcangio M. Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. The Journal of Clinical Investigation. 124: 2023-36. PMID 24743146 DOI: 10.1172/JCI71389  0.92
2013 Clark AK, Old EA, Malcangio M. Neuropathic pain and cytokines: current perspectives. Journal of Pain Research. 6: 803-14. PMID 24294006 DOI: 10.2147/JPR.S53660  0.64
2013 Kress M, Hüttenhofer A, Landry M, Kuner R, Favereaux A, Greenberg D, Bednarik J, Heppenstall P, Kronenberg F, Malcangio M, Rittner H, Uçeyler N, Trajanoski Z, Mouritzen P, Birklein F, et al. microRNAs in nociceptive circuits as predictors of future clinical applications. Frontiers in Molecular Neuroscience. 6: 33. PMID 24151455 DOI: 10.3389/fnmol.2013.00033  0.92
2013 Ogbonna AC, Clark AK, Gentry C, Hobbs C, Malcangio M. Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. European Journal of Pain (London, England). 17: 514-26. PMID 23169679 DOI: 10.1002/j.1532-2149.2012.00223.x  0.64
2012 Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio M, Wood JN. Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nature Communications. 3: 791. PMID 22531176 DOI: 10.1038/ncomms1795  0.92
2012 Clark AK, Grist J, Al-Kashi A, Perretti M, Malcangio M. Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. Arthritis and Rheumatism. 64: 2038-47. PMID 22213084 DOI: 10.1002/art.34351  0.64
2012 Clark AK, Malcangio M. Microglial signalling mechanisms: Cathepsin S and Fractalkine. Experimental Neurology. 234: 283-92. PMID 21946268 DOI: 10.1016/j.expneurol.2011.09.012  0.64
2011 Clark AK, Staniland AA, Malcangio M. Fractalkine/CX3CR1 signalling in chronic pain and inflammation. Current Pharmaceutical Biotechnology. 12: 1707-14. PMID 21466443  0.64
2011 Fernandes ES, Russell FA, Spina D, McDougall JJ, Graepel R, Gentry C, Staniland AA, Mountford DM, Keeble JE, Malcangio M, Bevan S, Brain SD. A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis Arthritis and Rheumatism. 63: 819-829. PMID 21360511 DOI: 10.1002/art.30150  0.92
2011 Leger T, Grist J, D'Acquisto F, Clark AK, Malcangio M. Glatiramer acetate attenuates neuropathic allodynia through modulation of adaptive immune cells. Journal of Neuroimmunology. 234: 19-26. PMID 21295862 DOI: 10.1016/j.jneuroim.2011.01.005  0.64
2010 Kaan TK, Yip PK, Patel S, Davies M, Marchand F, Cockayne DA, Nunn PA, Dickenson AH, Ford AP, Zhong Y, Malcangio M, McMahon SB. Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain : a Journal of Neurology. 133: 2549-64. PMID 20802203 DOI: 10.1093/brain/awq194  0.92
2010 Clark AK, Wodarski R, Guida F, Sasso O, Malcangio M. Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor. Glia. 58: 1710-26. PMID 20629190 DOI: 10.1002/glia.21042  0.64
2010 Staniland AA, Clark AK, Wodarski R, Sasso O, Maione F, D'Acquisto F, Malcangio M. Reduced inflammatory and neuropathic pain and decreased spinal microglial response in fractalkine receptor (CX3CR1) knockout mice. Journal of Neurochemistry. 114: 1143-57. PMID 20524966 DOI: 10.1111/j.1471-4159.2010.06837.x  0.64
2010 Clark AK, Staniland AA, Marchand F, Kaan TK, McMahon SB, Malcangio M. P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 573-82. PMID 20071520 DOI: 10.1523/JNEUROSCI.3295-09.2010  0.92
2010 Luongo L, Palazzo E, Tambaro S, Giordano C, Gatta L, Scafuro MA, Rossi FS, Lazzari P, Pani L, de Novellis V, Malcangio M, Maione S. 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiology of Disease. 37: 177-85. PMID 19804829 DOI: 10.1016/j.nbd.2009.09.021  0.92
2010 Clark AK, Marchand F, D' Auria M, Davies M, Grist J, Malcangio M, McMahon SB. Cathepsin S inhibition attenuates neuropathic pain and microglial response associated with spinal cord injury Open Pain Journal. 3: 117-122.  0.92
2009 McMahon SB, Malcangio M. Current challenges in glia-pain biology. Neuron. 64: 46-54. PMID 19840548 DOI: 10.1016/j.neuron.2009.09.033  0.92
2009 Clark AK, Yip PK, Malcangio M. The liberation of fractalkine in the dorsal horn requires microglial cathepsin S. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6945-54. PMID 19474321 DOI: 10.1523/JNEUROSCI.0828-09.2009  0.64
2009 Ji RR, Gereau RW, Malcangio M, Strichartz GR. MAP kinase and pain. Brain Research Reviews. 60: 135-48. PMID 19150373 DOI: 10.1016/j.brainresrev.2008.12.011  0.92
2009 Abbadie C, Bhangoo S, De Koninck Y, Malcangio M, Melik-Parsadaniantz S, White FA. Chemokines and pain mechanisms. Brain Research Reviews. 60: 125-34. PMID 19146875 DOI: 10.1016/j.brainresrev.2008.12.002  0.92
2009 Keeble JE, Bodkin JV, Liang L, Wodarski R, Davies M, Fernandes ES, Coelho CdF, Russell F, Graepel R, Muscara MN, Malcangio M, Brain SD. Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms Pain. 141: 135-142. PMID 19059721 DOI: 10.1016/j.pain.2008.10.025  0.92
2009 Wodarski R, Clark AK, Grist J, Marchand F, Malcangio M. Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats. European Journal of Pain (London, England). 13: 807-11. PMID 18977160 DOI: 10.1016/j.ejpain.2008.09.010  0.64
2009 Clark AK, Malcangio M. The cathepsin S/fractalkine pair: New players in spinal cord neuropathic pain mechanisms Synaptic Plasticity in Pain. 455-471. DOI: 10.1007/978-1-4419-0226-9_22  0.64
2008 Irie O, Kosaka T, Kishida M, Sakaki J, Masuya K, Konishi K, Yokokawa F, Ehara T, Iwasaki A, Iwaki Y, Hitomi Y, Toyao A, Gunji H, Teno N, Iwasaki G, ... ... Malcangio M, et al. Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2. Bioorganic & Medicinal Chemistry Letters. 18: 5280-4. PMID 18783943 DOI: 10.1016/j.bmcl.2008.08.067  0.92
2008 Irie O, Kosaka T, Ehara T, Yokokawa F, Kanazawa T, Hirao H, Iwasaki A, Sakaki J, Teno N, Hitomi Y, Iwasaki G, Fukaya H, Nonomura K, Tanabe K, Koizumi S, ... ... Malcangio M, et al. Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain. Journal of Medicinal Chemistry. 51: 5502-5. PMID 18754655 DOI: 10.1021/jm800839j  0.92
2008 Bordet T, Buisson B, Michaud M, Abitbol JL, Marchand F, Grist J, Andriambeloson E, Malcangio M, Pruss RM. Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy. The Journal of Pharmacology and Experimental Therapeutics. 326: 623-32. PMID 18492948 DOI: 10.1124/jpet.108.139410  0.64
2008 Luongo L, Sajic M, Grist J, Clark AK, Maione S, Malcangio M. Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barré syndrome. Neuroscience Letters. 437: 98-102. PMID 18448252 DOI: 10.1016/j.neulet.2008.04.019  0.64
2008 Pezet S, Marchand F, D'Mello R, Grist J, Clark AK, Malcangio M, Dickenson AH, Williams RJ, McMahon SB. Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4261-70. PMID 18417706 DOI: 10.1523/JNEUROSCI.5392-07.2008  0.92
2007 Clark AK, Yip PK, Grist J, Gentry C, Staniland AA, Marchand F, Dehvari M, Wotherspoon G, Winter J, Ullah J, Bevan S, Malcangio M. Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. 104: 10655-60. PMID 17551020 DOI: 10.1073/pnas.0610811104  0.92
2007 Barclay J, Clark AK, Ganju P, Gentry C, Patel S, Wotherspoon G, Buxton F, Song C, Ullah J, Winter J, Fox A, Bevan S, Malcangio M. Role of the cysteine protease cathepsin S in neuropathic hyperalgesia. Pain. 130: 225-34. PMID 17250968 DOI: 10.1016/j.pain.2006.11.017  0.92
2007 Clark AK, Gentry C, Bradbury EJ, McMahon SB, Malcangio M. Role of spinal microglia in rat models of peripheral nerve injury and inflammation. European Journal of Pain (London, England). 11: 223-30. PMID 16545974 DOI: 10.1016/j.ejpain.2006.02.003  0.92
2006 Bennett DL, Boucher TJ, Michael GJ, Popat RJ, Malcangio M, Averill SA, Poulsen KT, Priestley JV, Shelton DL, McMahon SB. Artemin has potent neurotrophic actions on injured C-fibres. Journal of the Peripheral Nervous System : Jpns. 11: 330-45. PMID 17117942 DOI: 10.1111/j.1529-8027.2006.00106.x  0.92
2006 Clark AK, D'Aquisto F, Gentry C, Marchand F, McMahon SB, Malcangio M. Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation. Journal of Neurochemistry. 99: 868-80. PMID 16942597 DOI: 10.1111/j.1471-4159.2006.04126.x  0.92
2004 Brooks JW, Thompson SW, Rice AS, Malcangio M. (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A. Neuroscience Letters. 372: 85-8. PMID 15531093 DOI: 10.1016/j.neulet.2004.09.014  0.92
2004 Fernihough J, Gentry C, Malcangio M, Fox A, Rediske J, Pellas T, Kidd B, Bevan S, Winter J. Pain related behaviour in two models of osteoarthritis in the rat knee. Pain. 112: 83-93. PMID 15494188 DOI: 10.1016/j.pain.2004.08.004  0.64
2004 Pezet S, Malcangio M. Brain-derived neurotrophic factor as a drug target for CNS disorders. Expert Opinion On Therapeutic Targets. 8: 391-9. PMID 15469390 DOI: 10.1517/14728222.8.5.391  0.8
2004 Slack SE, Pezet S, McMahon SB, Thompson SW, Malcangio M. Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord. The European Journal of Neuroscience. 20: 1769-78. PMID 15379998 DOI: 10.1111/j.1460-9568.2004.03656.x  0.92
2003 Kalmar B, Greensmith L, Malcangio M, McMahon SB, Csermely P, Burnstock G. The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury. Experimental Neurology. 184: 636-47. PMID 14769355 DOI: 10.1016/S0014-4886(03)00343-1  0.8
2003 Lever IJ, Grant AD, Pezet S, Gerard NP, Brain SD, Malcangio M. Basal and activity-induced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback. Neuropharmacology. 45: 1101-10. PMID 14614953 DOI: 10.1016/S0028-3908(03)00298-3  0.92
2003 Lever IJ, Pezet S, McMahon SB, Malcangio M. The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn. Molecular and Cellular Neurosciences. 24: 259-70. PMID 14572451 DOI: 10.1016/S1044-7431(03)00200-8  0.8
2003 Lever I, Cunningham J, Grist J, Yip PK, Malcangio M. Release of BDNF and GABA in the dorsal horn of neuropathic rats. The European Journal of Neuroscience. 18: 1169-74. PMID 12956715 DOI: 10.1046/j.1460-9568.2003.02848.x  0.64
2003 Lessmann V, Gottmann K, Malcangio M. Neurotrophin secretion: current facts and future prospects. Progress in Neurobiology. 69: 341-74. PMID 12787574 DOI: 10.1016/S0301-0082(03)00019-4  0.92
2003 Malcangio M, Lessmann V. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends in Pharmacological Sciences. 24: 116-21. PMID 12628355 DOI: 10.1016/S0165-6147(03)00025-7  0.92
2003 Neal M, Cunningham J, Lever I, Pezet S, Malcangio M. Mechanism by which brain-derived neurotrophic factor increases dopamine release from the rabbit retina. Investigative Ophthalmology & Visual Science. 44: 791-8. PMID 12556415 DOI: 10.1167/iovs.02-0557  0.8
2003 Costa SKP, Hyslop S, Malcangio M, Docherty RJ, Brain SD. Activation of 5-HT4 receptors causes neurogenic inflammation in the cutaneous microvasculature Inflammation Research. 52: S183-S186.  0.92
2002 Pezet S, Malcangio M, McMahon SB. BDNF: a neuromodulator in nociceptive pathways? Brain Research. Brain Research Reviews. 40: 240-9. PMID 12589922 DOI: 10.1016/S0165-0173(02)00206-0  0.8
2002 Pezet S, Malcangio M, Lever IJ, Perkinton MS, Thompson SW, Williams RJ, McMahon SB. Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Molecular and Cellular Neurosciences. 21: 684-95. PMID 12504600 DOI: 10.1006/mcne.2002.1205  0.8
2002 Pezet S, Cunningham J, Patel J, Grist J, Gavazzi I, Lever IJ, Malcangio M. BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn. Molecular and Cellular Neurosciences. 21: 51-62. PMID 12359151 DOI: 10.1006/mcne.2002.1166  0.8
2002 Malcangio M, Getting SJ, Grist J, Cunningham JR, Bradbury EJ, Charbel Issa P, Lever IJ, Pezet S, Perretti M. A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 730-2. PMID 11978739 DOI: 10.1096/fj.01-0971fje  0.8
2002 Lever IJ, Malcangio M. CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. British Journal of Pharmacology. 135: 21-4. PMID 11786475 DOI: 10.1038/sj.bjp.0704506  0.6
2001 Charbel Issa P, Lever IJ, Michael GJ, Bradbury EJ, Malcangio M. Intrathecally delivered glial cell line-derived neurotrophic factor produces electrically evoked release of somatostatin in the dorsal horn of the spinal cord. Journal of Neurochemistry. 78: 221-9. PMID 11461957 DOI: 10.1046/j.1471-4159.2001.00430.x  0.92
2001 Lever IJ, Bradbury EJ, Cunningham JR, Adelson DW, Jones MG, McMahon SB, Marvizón JC, Malcangio M. Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4469-77. PMID 11404434  0.8
2001 Meyer-Tuve A, Malcangio M, Ebersberger A, Mazario J, Schaible HG. Effect of brain-derived neurotrophic factor on the release of substance P from rat spinal cord. Neuroreport. 12: 21-4. PMID 11201084  0.92
2000 Malcangio M, Ramer MS, Jones MG, McMahon SB. Abnormal substance P release from the spinal cord following injury to primary sensory neurons. The European Journal of Neuroscience. 12: 397-9. PMID 10651897 DOI: 10.1046/j.1460-9568.2000.00946.x  0.92
2000 Malcangio M, Ramer MS, Boucher TJ, McMahon SB. Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord. The European Journal of Neuroscience. 12: 139-44. PMID 10651868 DOI: 10.1046/j.1460-9568.2000.00890.x  0.92
1996 Malcangio M, Bowery NG, Flower RJ, Perretti M. Effect of interleukin-1 beta on the release of substance P from rat isolated spinal cord. European Journal of Pharmacology. 299: 113-8. PMID 8901013 DOI: 10.1016/0014-2999(95)00845-4  0.32
1994 Smith GD, Harrison SM, Birch PJ, Elliott PJ, Malcangio M, Bowery NG. Increased sensitivity to the antinociceptive activity of (+/-)-baclofen in an animal model of chronic neuropathic, but not chronic inflammatory hyperalgesia. Neuropharmacology. 33: 1103-8. PMID 7838323 DOI: 10.1016/0028-3908(94)90149-X  0.92
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