Marzia Malcangio - Publications

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69/148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J, Perretti M, Sher E, Malcangio M. Imbalance of pro-resolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis. Pain. PMID 32379221 DOI: 10.1097/j.pain.0000000000001908  0.32
2017 Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T, Grist J, Al-Ahdal H, Wong LF, Perretti M, Lai J, Mouritzen P, Heppenstall P, ... Malcangio M, et al. Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. Nature Communications. 8: 1778. PMID 29176651 DOI: 10.1038/s41467-017-01841-5  0.64
2016 Nieto FR, Clark AK, Grist J, Hathway GJ, Chapman V, Malcangio M. Neuron-immune mechanisms contribute to pain in early stages of arthritis. Journal of Neuroinflammation. 13: 96. PMID 27130316 DOI: 10.1186/s12974-016-0556-0  0.92
2016 Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner. Arthritis Research & Therapy. 18: 7. PMID 26754745 DOI: 10.1186/s13075-015-0905-x  0.92
2015 Hansen RR, Vacca V, Pitcher T, Clark AK, Malcangio M. Role of extracellular calcitonin gene-related peptide in spinal cord mechanisms of cancer-induced bone pain. Pain. PMID 26574822 DOI: 10.1097/j.pain.0000000000000416  0.64
2015 Nicol LS, Dawes JM, La Russa F, Didangelos A, Clark AK, Gentry C, Grist J, Davies JB, Malcangio M, McMahon SB. The Role of G-Protein Receptor 84 in Experimental Neuropathic Pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8959-69. PMID 26063927 DOI: 10.1523/JNEUROSCI.3558-14.2015  0.92
2015 Ogbonna AC, Clark AK, Malcangio M. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. Age (Dordrecht, Netherlands). 37: 9792. PMID 25971876 DOI: 10.1007/s11357-015-9792-y  0.64
2015 Luongo L, Malcangio M, Salvemini D, Starowicz K. Chronic pain: new insights in molecular and cellular mechanisms. Biomed Research International. 2015: 676725. PMID 25879035 DOI: 10.1155/2015/676725  0.92
2015 Old EA, Clark AK, Malcangio M. The role of glia in the spinal cord in neuropathic and inflammatory pain. Handbook of Experimental Pharmacology. 227: 145-70. PMID 25846618 DOI: 10.1007/978-3-662-46450-2_8  0.64
2015 Clark AK, Gruber-Schoffnegger D, Drdla-Schutting R, Gerhold KJ, Malcangio M, Sandkühler J. Selective activation of microglia facilitates synaptic strength. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4552-70. PMID 25788673 DOI: 10.1523/JNEUROSCI.2061-14.2015  0.92
2015 Nieto FR, Clark AK, Grist J, Chapman V, Malcangio M. Calcitonin gene-related Peptide-expressing sensory neurons and spinal microglial reactivity contribute to pain States in collagen-induced arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1668-77. PMID 25707377 DOI: 10.1002/art.39082  0.92
2014 Clark AK, Malcangio M. Fractalkine/CX3CR1 signaling during neuropathic pain. Frontiers in Cellular Neuroscience. 8: 121. PMID 24847207 DOI: 10.3389/fncel.2014.00121  0.64
2014 Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim KW, Mogg AJ, Perretti M, Malcangio M. Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. The Journal of Clinical Investigation. 124: 2023-36. PMID 24743146 DOI: 10.1172/JCI71389  0.92
2013 Clark AK, Old EA, Malcangio M. Neuropathic pain and cytokines: current perspectives. Journal of Pain Research. 6: 803-14. PMID 24294006 DOI: 10.2147/JPR.S53660  0.64
2013 Kress M, Hüttenhofer A, Landry M, Kuner R, Favereaux A, Greenberg D, Bednarik J, Heppenstall P, Kronenberg F, Malcangio M, Rittner H, Uçeyler N, Trajanoski Z, Mouritzen P, Birklein F, et al. microRNAs in nociceptive circuits as predictors of future clinical applications. Frontiers in Molecular Neuroscience. 6: 33. PMID 24151455 DOI: 10.3389/fnmol.2013.00033  0.92
2013 Ogbonna AC, Clark AK, Gentry C, Hobbs C, Malcangio M. Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. European Journal of Pain (London, England). 17: 514-26. PMID 23169679 DOI: 10.1002/j.1532-2149.2012.00223.x  0.64
2012 Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio M, Wood JN. Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. Nature Communications. 3: 791. PMID 22531176 DOI: 10.1038/ncomms1795  0.92
2012 Clark AK, Grist J, Al-Kashi A, Perretti M, Malcangio M. Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. Arthritis and Rheumatism. 64: 2038-47. PMID 22213084 DOI: 10.1002/art.34351  0.64
2012 Clark AK, Malcangio M. Microglial signalling mechanisms: Cathepsin S and Fractalkine. Experimental Neurology. 234: 283-92. PMID 21946268 DOI: 10.1016/j.expneurol.2011.09.012  0.64
2011 Clark AK, Staniland AA, Malcangio M. Fractalkine/CX3CR1 signalling in chronic pain and inflammation. Current Pharmaceutical Biotechnology. 12: 1707-14. PMID 21466443  0.64
2011 Fernandes ES, Russell FA, Spina D, McDougall JJ, Graepel R, Gentry C, Staniland AA, Mountford DM, Keeble JE, Malcangio M, Bevan S, Brain SD. A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis Arthritis and Rheumatism. 63: 819-829. PMID 21360511 DOI: 10.1002/art.30150  0.92
2011 Leger T, Grist J, D'Acquisto F, Clark AK, Malcangio M. Glatiramer acetate attenuates neuropathic allodynia through modulation of adaptive immune cells. Journal of Neuroimmunology. 234: 19-26. PMID 21295862 DOI: 10.1016/j.jneuroim.2011.01.005  0.64
2010 Kaan TK, Yip PK, Patel S, Davies M, Marchand F, Cockayne DA, Nunn PA, Dickenson AH, Ford AP, Zhong Y, Malcangio M, McMahon SB. Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain : a Journal of Neurology. 133: 2549-64. PMID 20802203 DOI: 10.1093/brain/awq194  0.92
2010 Clark AK, Wodarski R, Guida F, Sasso O, Malcangio M. Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor. Glia. 58: 1710-26. PMID 20629190 DOI: 10.1002/glia.21042  0.64
2010 Staniland AA, Clark AK, Wodarski R, Sasso O, Maione F, D'Acquisto F, Malcangio M. Reduced inflammatory and neuropathic pain and decreased spinal microglial response in fractalkine receptor (CX3CR1) knockout mice. Journal of Neurochemistry. 114: 1143-57. PMID 20524966 DOI: 10.1111/j.1471-4159.2010.06837.x  0.64
2010 Clark AK, Staniland AA, Marchand F, Kaan TK, McMahon SB, Malcangio M. P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 573-82. PMID 20071520 DOI: 10.1523/JNEUROSCI.3295-09.2010  0.92
2010 Luongo L, Palazzo E, Tambaro S, Giordano C, Gatta L, Scafuro MA, Rossi FS, Lazzari P, Pani L, de Novellis V, Malcangio M, Maione S. 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiology of Disease. 37: 177-85. PMID 19804829 DOI: 10.1016/j.nbd.2009.09.021  0.92
2010 Clark AK, Marchand F, D' Auria M, Davies M, Grist J, Malcangio M, McMahon SB. Cathepsin S inhibition attenuates neuropathic pain and microglial response associated with spinal cord injury Open Pain Journal. 3: 117-122.  0.92
2009 McMahon SB, Malcangio M. Current challenges in glia-pain biology. Neuron. 64: 46-54. PMID 19840548 DOI: 10.1016/j.neuron.2009.09.033  0.92
2009 Clark AK, Yip PK, Malcangio M. The liberation of fractalkine in the dorsal horn requires microglial cathepsin S. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6945-54. PMID 19474321 DOI: 10.1523/JNEUROSCI.0828-09.2009  0.64
2009 Ji RR, Gereau RW, Malcangio M, Strichartz GR. MAP kinase and pain. Brain Research Reviews. 60: 135-48. PMID 19150373 DOI: 10.1016/j.brainresrev.2008.12.011  0.92
2009 Abbadie C, Bhangoo S, De Koninck Y, Malcangio M, Melik-Parsadaniantz S, White FA. Chemokines and pain mechanisms. Brain Research Reviews. 60: 125-34. PMID 19146875 DOI: 10.1016/j.brainresrev.2008.12.002  0.92
2009 Keeble JE, Bodkin JV, Liang L, Wodarski R, Davies M, Fernandes ES, Coelho CdF, Russell F, Graepel R, Muscara MN, Malcangio M, Brain SD. Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms Pain. 141: 135-142. PMID 19059721 DOI: 10.1016/j.pain.2008.10.025  0.92
2009 Wodarski R, Clark AK, Grist J, Marchand F, Malcangio M. Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats. European Journal of Pain (London, England). 13: 807-11. PMID 18977160 DOI: 10.1016/j.ejpain.2008.09.010  0.64
2009 Clark AK, Malcangio M. The cathepsin S/fractalkine pair: New players in spinal cord neuropathic pain mechanisms Synaptic Plasticity in Pain. 455-471. DOI: 10.1007/978-1-4419-0226-9_22  0.64
2008 Irie O, Kosaka T, Kishida M, Sakaki J, Masuya K, Konishi K, Yokokawa F, Ehara T, Iwasaki A, Iwaki Y, Hitomi Y, Toyao A, Gunji H, Teno N, Iwasaki G, ... ... Malcangio M, et al. Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2. Bioorganic & Medicinal Chemistry Letters. 18: 5280-4. PMID 18783943 DOI: 10.1016/j.bmcl.2008.08.067  0.92
2008 Irie O, Kosaka T, Ehara T, Yokokawa F, Kanazawa T, Hirao H, Iwasaki A, Sakaki J, Teno N, Hitomi Y, Iwasaki G, Fukaya H, Nonomura K, Tanabe K, Koizumi S, ... ... Malcangio M, et al. Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain. Journal of Medicinal Chemistry. 51: 5502-5. PMID 18754655 DOI: 10.1021/jm800839j  0.92
2008 Bordet T, Buisson B, Michaud M, Abitbol JL, Marchand F, Grist J, Andriambeloson E, Malcangio M, Pruss RM. Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy. The Journal of Pharmacology and Experimental Therapeutics. 326: 623-32. PMID 18492948 DOI: 10.1124/jpet.108.139410  0.64
2008 Luongo L, Sajic M, Grist J, Clark AK, Maione S, Malcangio M. Spinal changes associated with mechanical hypersensitivity in a model of Guillain-Barré syndrome. Neuroscience Letters. 437: 98-102. PMID 18448252 DOI: 10.1016/j.neulet.2008.04.019  0.64
2008 Pezet S, Marchand F, D'Mello R, Grist J, Clark AK, Malcangio M, Dickenson AH, Williams RJ, McMahon SB. Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4261-70. PMID 18417706 DOI: 10.1523/JNEUROSCI.5392-07.2008  0.92
2007 Clark AK, Yip PK, Grist J, Gentry C, Staniland AA, Marchand F, Dehvari M, Wotherspoon G, Winter J, Ullah J, Bevan S, Malcangio M. Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. 104: 10655-60. PMID 17551020 DOI: 10.1073/pnas.0610811104  0.92
2007 Barclay J, Clark AK, Ganju P, Gentry C, Patel S, Wotherspoon G, Buxton F, Song C, Ullah J, Winter J, Fox A, Bevan S, Malcangio M. Role of the cysteine protease cathepsin S in neuropathic hyperalgesia. Pain. 130: 225-34. PMID 17250968 DOI: 10.1016/j.pain.2006.11.017  0.92
2007 Clark AK, Gentry C, Bradbury EJ, McMahon SB, Malcangio M. Role of spinal microglia in rat models of peripheral nerve injury and inflammation. European Journal of Pain (London, England). 11: 223-30. PMID 16545974 DOI: 10.1016/j.ejpain.2006.02.003  0.92
2006 Bennett DL, Boucher TJ, Michael GJ, Popat RJ, Malcangio M, Averill SA, Poulsen KT, Priestley JV, Shelton DL, McMahon SB. Artemin has potent neurotrophic actions on injured C-fibres. Journal of the Peripheral Nervous System : Jpns. 11: 330-45. PMID 17117942 DOI: 10.1111/j.1529-8027.2006.00106.x  0.92
2006 Clark AK, D'Aquisto F, Gentry C, Marchand F, McMahon SB, Malcangio M. Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation. Journal of Neurochemistry. 99: 868-80. PMID 16942597 DOI: 10.1111/j.1471-4159.2006.04126.x  0.92
2004 Brooks JW, Thompson SW, Rice AS, Malcangio M. (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A. Neuroscience Letters. 372: 85-8. PMID 15531093 DOI: 10.1016/j.neulet.2004.09.014  0.92
2004 Fernihough J, Gentry C, Malcangio M, Fox A, Rediske J, Pellas T, Kidd B, Bevan S, Winter J. Pain related behaviour in two models of osteoarthritis in the rat knee. Pain. 112: 83-93. PMID 15494188 DOI: 10.1016/j.pain.2004.08.004  0.64
2004 Pezet S, Malcangio M. Brain-derived neurotrophic factor as a drug target for CNS disorders. Expert Opinion On Therapeutic Targets. 8: 391-9. PMID 15469390 DOI: 10.1517/14728222.8.5.391  0.8
2004 Slack SE, Pezet S, McMahon SB, Thompson SW, Malcangio M. Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord. The European Journal of Neuroscience. 20: 1769-78. PMID 15379998 DOI: 10.1111/j.1460-9568.2004.03656.x  0.92
2003 Kalmar B, Greensmith L, Malcangio M, McMahon SB, Csermely P, Burnstock G. The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury. Experimental Neurology. 184: 636-47. PMID 14769355 DOI: 10.1016/S0014-4886(03)00343-1  0.8
2003 Lever IJ, Grant AD, Pezet S, Gerard NP, Brain SD, Malcangio M. Basal and activity-induced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback. Neuropharmacology. 45: 1101-10. PMID 14614953 DOI: 10.1016/S0028-3908(03)00298-3  0.92
2003 Lever IJ, Pezet S, McMahon SB, Malcangio M. The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn. Molecular and Cellular Neurosciences. 24: 259-70. PMID 14572451 DOI: 10.1016/S1044-7431(03)00200-8  0.8
2003 Lever I, Cunningham J, Grist J, Yip PK, Malcangio M. Release of BDNF and GABA in the dorsal horn of neuropathic rats. The European Journal of Neuroscience. 18: 1169-74. PMID 12956715 DOI: 10.1046/j.1460-9568.2003.02848.x  0.64
2003 Lessmann V, Gottmann K, Malcangio M. Neurotrophin secretion: current facts and future prospects. Progress in Neurobiology. 69: 341-74. PMID 12787574 DOI: 10.1016/S0301-0082(03)00019-4  0.92
2003 Malcangio M, Lessmann V. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends in Pharmacological Sciences. 24: 116-21. PMID 12628355 DOI: 10.1016/S0165-6147(03)00025-7  0.92
2003 Neal M, Cunningham J, Lever I, Pezet S, Malcangio M. Mechanism by which brain-derived neurotrophic factor increases dopamine release from the rabbit retina. Investigative Ophthalmology & Visual Science. 44: 791-8. PMID 12556415 DOI: 10.1167/iovs.02-0557  0.8
2003 Costa SKP, Hyslop S, Malcangio M, Docherty RJ, Brain SD. Activation of 5-HT4 receptors causes neurogenic inflammation in the cutaneous microvasculature Inflammation Research. 52: S183-S186.  0.92
2002 Pezet S, Malcangio M, McMahon SB. BDNF: a neuromodulator in nociceptive pathways? Brain Research. Brain Research Reviews. 40: 240-9. PMID 12589922 DOI: 10.1016/S0165-0173(02)00206-0  0.8
2002 Pezet S, Malcangio M, Lever IJ, Perkinton MS, Thompson SW, Williams RJ, McMahon SB. Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Molecular and Cellular Neurosciences. 21: 684-95. PMID 12504600 DOI: 10.1006/mcne.2002.1205  0.8
2002 Pezet S, Cunningham J, Patel J, Grist J, Gavazzi I, Lever IJ, Malcangio M. BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn. Molecular and Cellular Neurosciences. 21: 51-62. PMID 12359151 DOI: 10.1006/mcne.2002.1166  0.8
2002 Malcangio M, Getting SJ, Grist J, Cunningham JR, Bradbury EJ, Charbel Issa P, Lever IJ, Pezet S, Perretti M. A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 730-2. PMID 11978739 DOI: 10.1096/fj.01-0971fje  0.8
2002 Lever IJ, Malcangio M. CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. British Journal of Pharmacology. 135: 21-4. PMID 11786475 DOI: 10.1038/sj.bjp.0704506  0.6
2001 Charbel Issa P, Lever IJ, Michael GJ, Bradbury EJ, Malcangio M. Intrathecally delivered glial cell line-derived neurotrophic factor produces electrically evoked release of somatostatin in the dorsal horn of the spinal cord. Journal of Neurochemistry. 78: 221-9. PMID 11461957 DOI: 10.1046/j.1471-4159.2001.00430.x  0.92
2001 Lever IJ, Bradbury EJ, Cunningham JR, Adelson DW, Jones MG, McMahon SB, Marvizón JC, Malcangio M. Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4469-77. PMID 11404434  0.8
2001 Meyer-Tuve A, Malcangio M, Ebersberger A, Mazario J, Schaible HG. Effect of brain-derived neurotrophic factor on the release of substance P from rat spinal cord. Neuroreport. 12: 21-4. PMID 11201084  0.92
2000 Malcangio M, Ramer MS, Jones MG, McMahon SB. Abnormal substance P release from the spinal cord following injury to primary sensory neurons. The European Journal of Neuroscience. 12: 397-9. PMID 10651897 DOI: 10.1046/j.1460-9568.2000.00946.x  0.92
2000 Malcangio M, Ramer MS, Boucher TJ, McMahon SB. Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord. The European Journal of Neuroscience. 12: 139-44. PMID 10651868 DOI: 10.1046/j.1460-9568.2000.00890.x  0.92
1996 Malcangio M, Bowery NG, Flower RJ, Perretti M. Effect of interleukin-1 beta on the release of substance P from rat isolated spinal cord. European Journal of Pharmacology. 299: 113-8. PMID 8901013 DOI: 10.1016/0014-2999(95)00845-4  0.32
1994 Smith GD, Harrison SM, Birch PJ, Elliott PJ, Malcangio M, Bowery NG. Increased sensitivity to the antinociceptive activity of (+/-)-baclofen in an animal model of chronic neuropathic, but not chronic inflammatory hyperalgesia. Neuropharmacology. 33: 1103-8. PMID 7838323 DOI: 10.1016/0028-3908(94)90149-X  0.92
Low-probability matches
2019 Chung K, Pitcher T, Grant AD, Hewitt E, Lindstrom E, Malcangio M. Cathepsin S acts via protease-activated receptor 2 to activate sensory neurons and induce itch-like behaviour. Neurobiology of Pain (Cambridge, Mass.). 6: 100032. PMID 31223140 DOI: 10.1016/j.ynpai.2019.100032  0.24
2017 Oehler B, Kistner K, Martin C, Schiller J, Mayer R, Mohammadi M, Sauer RS, Filipovic MR, Nieto FR, Kloka J, Pflücke D, Hill K, Schaefer M, Malcangio M, Reeh PW, et al. Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation. Scientific Reports. 7: 5447. PMID 28710476 DOI: 10.1038/s41598-017-05348-3  0.24
2009 Yip PK, Kaan TK, Fenesan D, Malcangio M. Rapid isolation and culture of primary microglia from adult mouse spinal cord. Journal of Neuroscience Methods. 183: 223-37. PMID 19596375 DOI: 10.1016/j.jneumeth.2009.07.002  0.24
2009 Malcangio M. Synaptic plasticity in pain Synaptic Plasticity in Pain. 1-504. DOI: 10.1007/978-1-4419-0226-9  0.24
2012 Old EA, Malcangio M. Chemokine mediated neuron-glia communication and aberrant signalling in neuropathic pain states. Current Opinion in Pharmacology. 12: 67-73. PMID 22056024 DOI: 10.1016/j.coph.2011.10.015  0.2
2003 Malcangio M. GDNF and somatostatin in sensory neurones. Current Opinion in Pharmacology. 3: 41-5. PMID 12550740 DOI: 10.1016/S1471-4892(02)00007-3  0.16
1996 Teoh H, Malcangio M, Bowery NG. GABA, glutamate and substance P-like immunoreactivity release: effects of novel GABAB antagonists. British Journal of Pharmacology. 118: 1153-60. PMID 8818338  0.01
1994 Malcangio M, Bowery NG. Spinal cord SP release and hyperalgesia in monoarthritic rats: involvement of the GABAB receptor system. British Journal of Pharmacology. 113: 1561-6. PMID 7534191  0.01
1993 Malcangio M, Bowery NG. Gamma-aminobutyric acidB, but not gamma-aminobutyric acidA receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitro. The Journal of Pharmacology and Experimental Therapeutics. 266: 1490-6. PMID 7690402  0.01
2019 Montague-Cardoso K, Pitcher T, Chisolm K, Salera G, Lindstrom E, Hewitt E, Solito E, Malcangio M. Changes in vascular permeability in the spinal cord contribute to chemotherapy-induced neuropathic pain. Brain, Behavior, and Immunity. PMID 31669344 DOI: 10.1016/j.bbi.2019.10.018  0.08
2018 Aman Y, Pitcher T, Ballard C, Malcangio M. Impaired chronic pain-like behaviour and altered opioidergic system in the TASTPM mouse model of Alzheimer's disease. European Journal of Pain (London, England). PMID 29987897 DOI: 10.1002/ejp.1288  0.08
2017 Sousa-Valente J, Calvo L, Vacca V, Simeoli R, Arévalo JC, Malcangio M. Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model. Osteoarthritis and Cartilage. PMID 28844566 DOI: 10.1016/j.joca.2017.08.006  0.08
2016 Hewitt E, Pitcher T, Rizoska B, Tunblad K, Henderson I, Sahlberg BL, Grabowska U, Classon B, Edenius C, Malcangio M, Lindstrom E. Selective cathepsin S inhibition with MIV-247 attenuates allodynia and enhances the anti-allodynic effects of gabapentin and pregabalin in a mouse model of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 27335437 DOI: 10.1124/jpet.116.232926  0.08
2016 Aman Y, Pitcher T, Simeoli R, Ballard C, Malcangio M. Reduced thermal sensitivity and increased opioidergic tone in the TASTPM mouse model of Alzheimer's disease. Pain. PMID 27306045 DOI: 10.1097/j.pain.0000000000000644  0.08
2016 Pitcher T, Sousa-Valente J, Malcangio M. The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse. Journal of Visualized Experiments : Jove. PMID 27214709 DOI: 10.3791/53746  0.08
2013 Hansen RR, Malcangio M. Astrocytes--multitaskers in chronic pain. European Journal of Pharmacology. 716: 120-8. PMID 23528354 DOI: 10.1016/j.ejphar.2013.03.023  0.08
1993 Malcangio M, Bowery NG. GABAB receptor-mediated inhibition of forskolin-stimulated cyclic AMP accumulation in rat spinal cord. Neuroscience Letters. 158: 189-92. PMID 8233093 DOI: 10.1016/0304-3940(93)90261-I  0.01
1992 Ghelardini C, Fantetti L, Malcangio M, Malmberg-Aiello P, Giotti A, Bartolini A. Involvement of central cholinergic neurotransmission in metoclopramide analgesia. Pharmacological Research. 25: 25-6. PMID 1324488 DOI: 10.1016/1043-6618(92)90523-E  0.01
2019 Rukavina K, Leta V, Sportelli C, Buhidma Y, Duty S, Malcangio M, Ray Chaudhuri K. Pain in Parkinson's disease: new concepts in pathogenesis and treatment. Current Opinion in Neurology. 32: 579-588. PMID 31260418 DOI: 10.1097/WCO.0000000000000711  0.04
2018 Montague K, Simeoli R, Valente J, Malcangio M. A novel interaction between CXCR and CCR signalling in monocytes constitutes an underlying mechanism for persistent vincristine-induced pain. Journal of Neuroinflammation. 15: 101. PMID 29625610 DOI: 10.1186/s12974-018-1116-6  0.04
1997 Malcangio M, Garrett NE, Cruwys S, Tomlinson DR. Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8459-67. PMID 9334418  0.01
1997 Malcangio M, Garrett NE, Tomlinson DR. Nerve growth factor treatment increases stimulus-evoked release of sensory neuropeptides in the rat spinal cord. The European Journal of Neuroscience. 9: 1101-4. PMID 9182964 DOI: 10.1111/j.1460-9568.1997.tb01462.x  0.01
1997 Garrett NE, Malcangio M, Dewhurst M, Tomlinson DR. alpha-Lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support. Neuroscience Letters. 222: 191-4. PMID 9148247 DOI: 10.1016/S0304-3940(97)13383-3  0.04
1997 Tomlinson DR, Fernyhough P, Mohiuddin L, Delcroix JD, Malcangio M. Neurotrophic factors - regulation of neuronal phenotype Neuroscience Research Communications. 21: 57-66. DOI: 10.1002/(SICI)1520-6769(199707)21:1<57::AID-NRC208>3.0.CO;2-V  0.01
1996 Malcangio M, Bowery NG. GABA and its receptors in the spinal cord. Trends in Pharmacological Sciences. 17: 457-62. PMID 9014500 DOI: 10.1016/S0165-6147(96)01013-9  0.01
1996 Malcangio M, Bowery NG. Calcitonin gene-related peptide content, basal outflow and electrically-evoked release from monoarthritic rat spinal cord in vitro. Pain. 66: 351-8. PMID 8880859 DOI: 10.1016/0304-3959(96)03036-9  0.01
1995 Malcangio M, Bowery NG. Possible therapeutic application of GABAB receptor agonists and antagonists. Clinical Neuropharmacology. 18: 285-305. PMID 8665542  0.01
1995 Castro-Lopes JM, Malcangio M, Pan BH, Bowery NG. Complex changes of GABAA and GABAB receptor binding in the spinal cord dorsal horn following peripheral inflammation or neurectomy. Brain Research. 679: 289-97. PMID 7633890 DOI: 10.1016/0006-8993(95)00262-O  0.01
1987 Bartolini A, Galli A, Ghelardini C, Giotti A, Malcangio M, Malmberg-Aiello P, Zucchi PL. Antinociception induced by systemic administration of local anaesthetics depends on a central cholinergic mechanism. British Journal of Pharmacology. 92: 711-21. PMID 3427277  0.01
2020 Montague-Cardoso K, Malcangio M. Cathepsin S as a potential therapeutic target for chronic pain. Medicine in Drug Discovery. 7: 100047. PMID 32904424 DOI: 10.1016/j.medidd.2020.100047  0.01
2020 Montague-Cardoso K, Malcangio M. The role of microRNAs in neurons and neuroimmune communication in the dorsal root ganglia in chronic pain. Neuroscience Letters. 735: 135230. PMID 32621949 DOI: 10.1016/j.neulet.2020.135230  0.01
2020 Malcangio M. Translational value of preclinical models for rheumatoid arthritis pain. Pain. PMID 32168004 DOI: 10.1097/j.pain.0000000000001851  0.01
2020 Montague-Cardoso K, Malcangio M. Cathepsin S as a potential therapeutic target for chronic pain Medicine in Drug Discovery. 7: 100047. DOI: 10.1016/j.medidd.2020.100047  0.01
2020 Montague-Cardoso K, Mrozkova P, Malcangio M. The Role of Spinal Cord CX3CL1/CX3CR1 Signalling in Chronic Pain Current Tissue Microenvironment Reports. 1: 23-29. DOI: 10.1007/s43152-020-00006-9  0.01
2019 Malcangio M. Role of the immune system in neuropathic pain. Scandinavian Journal of Pain. PMID 31730538 DOI: 10.1515/sjpain-2019-0138  0.01
2018 Georgieva M, Leeson-Payne A, Dumitrascuta M, Rajnicek A, Malcangio M, Huang W. A refined rat primary neonatal microglial culture method that reduces time, cost and animal use. Journal of Neuroscience Methods. PMID 29705403 DOI: 10.1016/j.jneumeth.2018.04.017  0.01
2018 Malcangio M. i011 Inflammation: initiation and maintenance of peripheral and central sensitisation Rheumatology. 57. DOI: 10.1093/rheumatology/key075.011  0.01
2017 Malcangio M. Spinal mechanisms of neuropathic pain: Is there a P2X4-BDNF controversy? Neurobiology of Pain (Elsevier). 1: 1-5. PMID 30272037 DOI: 10.1016/j.ynpai.2017.04.001  0.01
2017 Montague K, Malcangio M. The Therapeutic Potential of Monocyte/Macrophage Manipulation in the Treatment of Chemotherapy-Induced Painful Neuropathy. Frontiers in Molecular Neuroscience. 10: 397. PMID 29230166 DOI: 10.3389/fnmol.2017.00397  0.01
2017 Nascimento DSM, Potes CS, Soares ML, Ferreira AC, Malcangio M, Castro-Lopes JM, Neto FLM. Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG. Molecular Neurobiology. PMID 28550532 DOI: 10.1007/s12035-017-0628-x  0.01
2017 Malcangio M. GABAB receptors and pain. Neuropharmacology. PMID 28504122 DOI: 10.1016/j.neuropharm.2017.05.012  0.01
2016 Montague K, Malcangio M. The therapeutic potential of targeting chemokine signalling in the treatment of chronic pain. Journal of Neurochemistry. PMID 27973687 DOI: 10.1111/jnc.13927  0.01
2016 Malcangio M. Microglia and chronic pain. Pain. 157: 1002-3. PMID 27081836 DOI: 10.1097/j.pain.0000000000000353  0.01
2015 Dib-Hajj SD, Waxman SG. Diversity of composition and function of sodium channels in peripheral sensory neurons. Pain. 156: 2406-7. PMID 26580678 DOI: 10.1097/j.pain.0000000000000353  0.01
2012 Corbett A, Husebo B, Malcangio M, Staniland A, Cohen-Mansfield J, Aarsland D, Ballard C. Assessment and treatment of pain in people with dementia. Nature Reviews. Neurology. 8: 264-74. PMID 22487749 DOI: 10.1038/nrneurol.2012.53  0.01
2009 Staniland A, Malcangio M. 181 ABSENCE OF THERMAL HYPERALGESIA AFTER PERIPHERAL INFLAMMATION IN MICE LACKING THE FRACTALKINE RECEPTOR CX3CR1 European Journal of Pain. 13: S61. DOI: 10.1016/S1090-3801(09)60184-1  0.01
2009 Clark A, Wodarski R, Malcangio M. 174 CX3CR1 RECEPTOR IS REQUIRED FOR FULL DEVELOPMENT OF NOCICEPTIVE BEHAVIOUR FOLLOWING PERIPHERAL NERVE INJURY European Journal of Pain. 13: S59. DOI: 10.1016/S1090-3801(09)60177-4  0.01
2007 Pruss R, Buisson B, Cuvier V, Abitbol J, Marchand F, Grist J, Malcangio M, Bordet T. 163 TRO19622 TARGETS MITOCHONDRIA AND REVERSES PAIN IN ANIMAL MODELS OF NEUROPATHIC PAIN European Journal of Pain. 11: S70-S71. DOI: 10.1016/j.ejpain.2007.03.178  0.01
2006 Aman Y, Troakes C, Ballard C, Malcangio M. P2-010: INVOLVEMENT OF ELEVATED NEUROINFLAMMATION IN KEY REGIONS OF THE PAIN PATHWAY IN NOCICEPTIVE PROCESSING IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P668-P668. DOI: 10.1016/j.jalz.2018.06.694  0.01
2006 Aman Y, Pitcher T, Ballard C, Malcangio M. P4-018: IMPAIRED CHRONIC PAIN-LIKE BEHAVIOUR AND DISRUPTION OF OPIOIDERGIC SYSTEM IN TASTPM MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1439-P1440. DOI: 10.1016/j.jalz.2018.06.2420  0.01
2004 Lessmann V, Gottmann K, Malcangio M. Erratum to “Neurotrophin secretion: current facts and future prospects” [Progr. Neurobiol. 69 (2003) 341–374] Progress in Neurobiology. 72: 165-166. DOI: 10.1016/j.pneurobio.2004.02.003  0.01
1999 Malcangio M, Bowery NG. Peptide autoreceptors: does an autoreceptor for substance P exist? Trends in Pharmacological Sciences. 20: 405-7. PMID 10577252 DOI: 10.1016/S0165-6147(99)01388-7  0.01
1999 Riaz S, Malcangio M, Miller M, Tomlinson DR. A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats. Diabetologia. 42: 1308-13. PMID 10550414 DOI: 10.1007/s001250051443  0.01
1998 Malcangio M, Fernandes K, Tomlinson DR. NMDA receptor activation modulates evoked release of substance P from rat spinal cord. British Journal of Pharmacology. 125: 1625-6. PMID 9886751 DOI: 10.1038/sj.bjp.0702260  0.01
1998 Malcangio M, Tomlinson DR. A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats. Pain. 76: 151-7. PMID 9696468 DOI: 10.1016/S0304-3959(98)00037-2  0.01
1996 Teoh H, Malcangio M, Fowler LJ, Bowery NG. Evidence for release of glutamic acid, aspartic acid and substance P but not gamma-aminobutyric acid from primary afferent fibres in rat spinal cord. European Journal of Pharmacology. 302: 27-36. PMID 8790988 DOI: 10.1016/0014-2999(96)00052-0  0.01
1996 Malcangio M, Bowery NG. GABAB Receptors and Antinociception Pharmacology Reviews and Communications. 8: 195-196.  0.01
1996 Malcangio M, Bowery NG. GABA(B) receptors and antinociception Pharmacology Communications. 8: 195-196.  0.01
1995 Malcangio M, Libri V, Teoh H, Constanti A, Bowery NG. Chronic (-)baclofen or CGP 36742 alters GABAB receptor sensitivity in rat brain and spinal cord. Neuroreport. 6: 399-403. PMID 7538812  0.01
1994 Malcangio M, Bowery NG. Effect of the tachykinin NK1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cord. British Journal of Pharmacology. 113: 635-41. PMID 7530576  0.01
1993 Malcangio M, Da Silva H, Bowery NG. Plasticity of GABAB receptor in rat spinal cord detected by autoradiography. European Journal of Pharmacology. 250: 153-6. PMID 8119313 DOI: 10.1016/0014-2999(93)90633-S  0.01
1992 Bartolini A, Ghelardini C, Fantetti L, Malcangio M, Malmberg-Aiello P, Giotti A. Role of muscarinic receptor subtypes in central antinociception. British Journal of Pharmacology. 105: 77-82. PMID 1375858  0.01
1992 Malcangio M, Malmberg-Aiello P, Giotti A, Ghelardini C, Bartolini A. Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception. Neuropharmacology. 31: 783-91. PMID 1326728 DOI: 10.1016/0028-3908(92)90042-N  0.01
1991 Malcangio M, Ghelardini C, Giotti A, Malmberg-Aiello P, Bartolini A. CGP 35348, a new GABAB antagonist, prevents antinociception and muscle-relaxant effect induced by baclofen. British Journal of Pharmacology. 103: 1303-8. PMID 1653069  0.01
1990 Malcangio M, Pizzighelli L, Ghelardini C, Malmberg-Aiello P, Giotti A, Bartolini A. Cross-tolerance between baclofen and bicuculline antinociception. Pharmacological Research. 22: 5-6. PMID 2284247  0.01
1990 Ghelardini C, Malmberg-Aiello P, Giotti A, Malcangio M, Bartolini A. Investigation into atropine-induced antinociception. British Journal of Pharmacology. 101: 49-54. PMID 2282466  0.01
1990 Malcangio M, Pizzighelli L, Fantetti L, Ghelardini C, Giotti A, Malmberg-Aiello P, Bartolini A. Effect of GM1 ganglioside on amnesia, convulsions and death caused by hypoxia in mice Pharmacological Research. 22: 291. DOI: 10.1016/S1043-6618(09)80320-4  0.01
1990 Fantetti L, Ghelardini C, Malcangio M, Malmberg-Aiello, P, Giotti A, Bartolini A. Central antinociceptive effect of minaprine Pharmacological Research. 22: 188. DOI: 10.1016/S1043-6618(09)80229-6  0.01
1990 Bartolini A, Ghelardini C, Malcangio M, Fantetti L, Malmberg-Aiello P, Giotti A. Investigation into analgesia induced by haloperidol Pharmacological Research. 22: 30. DOI: 10.1016/S1043-6618(09)80086-8  0.01
1990 Malcangio M, Pizzighelli L, Ghelardini C, Malmberg-Aiello P, Toffano G, Giotti A, Bartolini A. Morphine tolerance is inhibited by chronic treatment with GM1 ganglioside European Journal of Pharmacology. 183: 977. DOI: 10.1016/0014-2999(90)92820-9  0.01
1990 Bartolini A, Ghelardini C, Malcangio M, Malmberg-Aiello P, Giotti A. Amplification of cholinergic neurotransmission induced by the selective muscarinic M2 antagonist AFDX-116 European Journal of Pharmacology. 183: 2044. DOI: 10.1016/0014-2999(90)92407-A  0.01
1990 Ghelardini L, Fantetti L, Malcangio M, Malmberg-Aiello P, Giotti A, Bartolini A. Central muscarinic analgesia is mediated by M1 receptors European Journal of Pharmacology. 183: 1941-1942. DOI: 10.1016/0014-2999(90)92288-T  0.01
1989 Malcangio M, Bartolini A, Ghelardini C, Bennardini F, Malmberg-Aiello P, Franconi F, Giotti A. Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia. Psychopharmacology. 98: 316-20. PMID 2501810  0.01
1988 Bartolini A, Ghelardini C, Meini S, Malmberg-Aiello P, Malcangio M, Giotti A. The stimulating action of very low doses of antagonist drugs, or the otherwise generally higher sensitivity of presynaptic autoreceptors Pharmacological Research Communications. 20: 59-60. DOI: 10.1016/S0031-6989(88)80640-4  0.01
1988 Meini S, Ghelardini C, Malcangio M, Del Buono C, Bartolini A, Giotti A, Malmberg-Aiello P. Antihistaminic antinociception: Research about mechanism of action Pharmacological Research Communications. 20: 236. DOI: 10.1016/S0031-6989(88)80366-7  0.01
1988 Malcangio M, Quarta S, Del Buono C, Ghelardini C, Malmberg-Aiello P, Meini S, Giotti A, Bartolini A. Effect of procaine on learning and hypoxia-induced amnesia Pharmacological Research Communications. 20: 220. DOI: 10.1016/S0031-6989(88)80350-3  0.01
1988 Ghelardini C, Meini S, Malmberg-Aiello P, Malcangio M, Del Buono C, Bartolini A, Giotti A. Studies on the analgesic mechanism of some antiarrhythmic drugs Pharmacological Research Communications. 20: 177. DOI: 10.1016/S0031-6989(88)80307-2  0.01
1988 Del Buono C, Malcangio M, Zevgoli S, Ghelardini C, Giotti A, Malmberg-Aiello P, Meini S, Bartolini A. Procaine antidepressant effect Pharmacological Research Communications. 20: 132. DOI: 10.1016/S0031-6989(88)80262-5  0.01
1987 Bennardini F, Failli P, Matucci R, Bartolini A, Malcangio M, Massari M, Franconi F, Giotti A. L-arginine methylester reduces Ca2+/Cl(-)-dependent L-[3H]glutamate binding and Ca2+-activated neutral protease activity in rat hippocampal membranes. Fundamental & Clinical Pharmacology. 1: 297-306. PMID 3327795  0.01
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