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Kevin M. Esvelt, Ph.D. - Publications

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Smidler AL, Marrogi E, Kauffman J, Paton DG, Westervelt KA, Church GM, Esvelt KM, Shaw WR, Catteruccia F. CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males. Scientific Reports. 14: 4057. PMID 38374393 DOI: 10.1038/s41598-024-54498-8  0.421
2023 Smidler AL, Paton DG, Church GM, Esvelt KM, Shaw WR, Catteruccia F. CRISPR-mediated germline mutagenesis for genetic sterilization of males. Biorxiv : the Preprint Server For Biology. PMID 37398131 DOI: 10.1101/2023.06.13.544841  0.416
2022 DeBenedictis EA, Söll D, Esvelt KM. Measuring the tolerance of the genetic code to altered codon size. Elife. 11. PMID 35293861 DOI: 10.7554/eLife.76941  0.708
2021 DeBenedictis EA, Chory EJ, Gretton DW, Wang B, Golas S, Esvelt KM. Systematic molecular evolution enables robust biomolecule discovery. Nature Methods. PMID 34969982 DOI: 10.1038/s41592-021-01348-4  0.74
2021 Biswas S, Khimulya G, Alley EC, Esvelt KM, Church GM. Low-N protein engineering with data-efficient deep learning. Nature Methods. 18: 389-396. PMID 33828272 DOI: 10.1038/s41592-021-01100-y  0.451
2021 Chory EJ, Gretton DW, DeBenedictis EA, Esvelt KM. Enabling high-throughput biology with flexible open-source automation. Molecular Systems Biology. 17: e9942. PMID 33764680 DOI: 10.15252/msb.20209942  0.716
2020 Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen CH, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, et al. Core commitments for field trials of gene drive organisms. Science (New York, N.Y.). 370: 1417-1419. PMID 33335055 DOI: 10.1126/science.abd1908  0.384
2020 Lewis G, Jordan JL, Relman DA, Koblentz GD, Leung J, Dafoe A, Nelson C, Epstein GL, Katz R, Montague M, Alley EC, Filone CM, Luby S, Church GM, Millett P, ... Esvelt KM, et al. The biosecurity benefits of genetic engineering attribution. Nature Communications. 11: 6294. PMID 33293537 DOI: 10.1038/s41467-020-19149-2  0.437
2020 Alley EC, Turpin M, Liu AB, Kulp-McDowall T, Swett J, Edison R, Von Stetina SE, Church GM, Esvelt KM. A machine learning toolkit for genetic engineering attribution to facilitate biosecurity. Nature Communications. 11: 6293. PMID 33293535 DOI: 10.1038/s41467-020-19612-0  0.397
2019 Noble C, Min J, Olejarz J, Buchthal J, Chavez A, Smidler AL, DeBenedictis EA, Church GM, Nowak MA, Esvelt KM. Daisy-chain gene drives for the alteration of local populations. Proceedings of the National Academy of Sciences of the United States of America. PMID 30940750 DOI: 10.1073/Pnas.1716358116  0.757
2019 Buchthal J, Evans SW, Lunshof J, Telford SR, Esvelt KM. Mice Against Ticks: an experimental community-guided effort to prevent tick-borne disease by altering the shared environment. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 374: 20180105. PMID 30905296 DOI: 10.1098/Rstb.2018.0105  0.34
2018 Esvelt KM. Inoculating science against potential pandemics and information hazards. Plos Pathogens. 14: e1007286. PMID 30286188 DOI: 10.1371/Journal.Ppat.1007286  0.311
2018 Noble C, Adlam B, Church GM, Esvelt KM, Nowak MA. Current CRISPR gene drive systems are likely to be highly invasive in wild populations. Elife. 7. PMID 29916367 DOI: 10.7554/Elife.33423  0.53
2018 Najjar DA, Normandin AM, Strait EA, Esvelt KM. Driving towards ecotechnologies. Pathogens and Global Health. 1-11. PMID 29629849 DOI: 10.1080/20477724.2018.1452844  0.365
2018 Noble C, Adlam B, Church GM, Esvelt KM, Nowak MA. Author response: Current CRISPR gene drive systems are likely to be highly invasive in wild populations Elife. DOI: 10.7554/Elife.33423.021  0.508
2017 Esvelt KM, Gemmell NJ. Conservation demands safe gene drive. Plos Biology. 15: e2003850. PMID 29145398 DOI: 10.1371/Journal.Pbio.2003850  0.366
2017 Noble C, Olejarz J, Esvelt KM, Church GM, Nowak MA. Evolutionary dynamics of CRISPR gene drives. Science Advances. 3: e1601964. PMID 28435878 DOI: 10.1126/Sciadv.1601964  0.584
2017 Min J, Smidler AL, Najjar D, Esvelt KM. Harnessing gene drive Journal of Responsible Innovation. 5: S40-S65. DOI: 10.1080/23299460.2017.1415586  0.386
2017 Kuzma J, Gould F, Brown Z, Collins J, Delborne J, Frow E, Esvelt K, Guston D, Leitschuh C, Oye K, Stauffer S. A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context Journal of Responsible Innovation. 5: S13-S39. DOI: 10.1080/23299460.2017.1410344  0.322
2016 Esvelt K. Gene editing can drive science to openness. Nature. 534: 153. PMID 27279174 DOI: 10.1038/534153A  0.329
2016 Braff JL, Yaung SJ, Esvelt KM, Church GM. Characterization of Cas9-Guide RNA Orthologs. Cold Spring Harbor Protocols. 2016: pdb.top086793. PMID 27140923 DOI: 10.1101/Pdb.Top086793  0.551
2016 Braff JL, Yaung SJ, Esvelt KM, Church GM. Characterizing Cas9 Protospacer-Adjacent Motifs with High-Throughput Sequencing of Library Depletion Experiments. Cold Spring Harbor Protocols. 2016: pdb.prot090183. PMID 27140916 DOI: 10.1101/Pdb.Prot090183  0.498
2015 DiCarlo JE, Chavez A, Dietz SL, Esvelt KM, Church GM. Safeguarding CRISPR-Cas9 gene drives in yeast. Nature Biotechnology. 33: 1250-1255. PMID 26571100 DOI: 10.1038/Nbt.3412  0.772
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932  0.475
2015 Yaung SJ, Esvelt KM, Church GM. Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68. Genome Announcements. 3. PMID 25555735 DOI: 10.1128/Genomea.01122-14  0.474
2014 Oye KA, Esvelt KM. Gene drives raise dual-use concerns--response. Science (New York, N.Y.). 345: 1010-1. PMID 25170143 DOI: 10.1126/Science.345.6200.1010-C  0.357
2014 Esvelt KM, Smidler AL, Catteruccia F, Church GM. Concerning RNA-guided gene drives for the alteration of wild populations. Elife. 3. PMID 25035423 DOI: 10.7554/Elife.03401  0.587
2014 Oye KA, Esvelt K, Appleton E, Catteruccia F, Church G, Kuiken T, Lightfoot SB, McNamara J, Smidler A, Collins JP. Biotechnology. Regulating gene drives. Science (New York, N.Y.). 345: 626-8. PMID 25035410 DOI: 10.1126/Science.1254287  0.54
2014 Yaung SJ, Esvelt KM, Church GM. CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4. Plos One. 9: e98811. PMID 24886988 DOI: 10.1371/Journal.Pone.0098811  0.462
2014 Esvelt KM, Smidler AL, Catteruccia F, Church GM. Author response: Concerning RNA-guided gene drives for the alteration of wild populations Elife. DOI: 10.7554/Elife.03401.019  0.537
2013 Mali P, Esvelt KM, Church GM. Cas9 as a versatile tool for engineering biology. Nature Methods. 10: 957-63. PMID 24076990 DOI: 10.1038/Nmeth.2649  0.715
2013 Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nature Methods. 10: 1116-21. PMID 24076762 DOI: 10.1038/nmeth.2681  0.708
2013 Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology. 31: 833-8. PMID 23907171 DOI: 10.1038/Nbt.2675  0.763
2013 Friedland AE, Tzur YB, Esvelt KM, Colaiácovo MP, Church GM, Calarco JA. Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nature Methods. 10: 741-3. PMID 23817069 DOI: 10.1038/Nmeth.2532  0.561
2013 Dickinson BC, Leconte AM, Allen B, Esvelt KM, Liu DR. Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution Proceedings of the National Academy of Sciences of the United States of America. 110: 9007-9012. PMID 23674678 DOI: 10.1073/Pnas.1220670110  0.764
2013 Esvelt KM, Wang HH. Genome-scale engineering for systems and synthetic biology. Molecular Systems Biology. 9: 641. PMID 23340847 DOI: 10.1038/Msb.2012.66  0.608
2013 Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. RNA-guided human genome engineering via Cas9. Science (New York, N.Y.). 339: 823-6. PMID 23287722 DOI: 10.1126/Science.1232033  0.751
2011 Lin A, Jimenez J, Derr J, Vera P, Manapat ML, Esvelt KM, Villanueva L, Liu DR, Chen IA. Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model. Plos One. 6: e19991. PMID 21637841 DOI: 10.1371/Journal.Pone.0019991  0.425
2011 Esvelt KM, Carlson JC, Liu DR. A system for the continuous directed evolution of biomolecules. Nature. 472: 499-503. PMID 21478873 DOI: 10.1038/Nature09929  0.709
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