Year |
Citation |
Score |
2022 |
Xu J, Grosslight S, Mack KA, Nguyen SC, Clagg K, Lim NK, Timmerman JC, Shen J, White NA, Sirois LE, Han C, Zhang H, Sigman MS, Gosselin F. Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036. Journal of the American Chemical Society. PMID 36326518 DOI: 10.1021/jacs.2c09917 |
0.324 |
|
2021 |
Zell D, Kingston C, Jermaks J, Smith SR, Seeger N, Wassmer J, Sirois LE, Han C, Zhang H, Sigman MS, Gosselin F. Stereoconvergent and -divergent Synthesis of Tetrasubstituted Alkenes by Nickel-Catalyzed Cross-Couplings. Journal of the American Chemical Society. 143: 19078-19090. PMID 34735129 DOI: 10.1021/jacs.1c08399 |
0.33 |
|
2019 |
Bigler R, Mack KA, Shen J, Tosatti P, Han C, Zhang H, Scalone M, Pfaltz A, Denmark SE, Hildbrand S, Gosselin F. Asymmetric Hydrogenation of Unfunctionalized, Tetrasubstituted, Acyclic Olefins. Angewandte Chemie (International Ed. in English). PMID 31794118 DOI: 10.1002/Anie.201912640 |
0.338 |
|
2019 |
Wong N, Petronijević F, Hong AY, Linghu X, Kelly SM, Hou H, Cravillion T, Lim NK, Robinson SJ, Han C, Molinaro C, Sowell CG, Gosselin F. Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338. Organic Letters. PMID 31668077 DOI: 10.1021/Acs.Orglett.9B03481 |
0.429 |
|
2019 |
Han C, Alabanza LM, Kelly SM, Orsi DL, Gosselin F, Altman RA. BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale Organic Process Research & Development. 23: 1695-1702. DOI: 10.1021/Acs.Oprd.9B00201 |
0.599 |
|
2019 |
Han C, Kelly SM, Cravillion T, Savage SJ, Nguyen T, Gosselin F. Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids Tetrahedron. 75: 4351-4357. DOI: 10.1016/J.Tet.2019.04.057 |
0.461 |
|
2018 |
Savage S, McClory A, Zhang H, Cravillion T, Lim NK, Masui C, Robinson SJ, Han C, Ochs C, Rege PD, Gosselin F. Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin. The Journal of Organic Chemistry. PMID 30200756 DOI: 10.1021/Acs.Joc.8B01551 |
0.41 |
|
2018 |
Young IS, Glass AL, Cravillion T, Han C, Zhang H, Gosselin F. Palladium-Catalyzed Site-Selective Amidation of Dichloroazines. Organic Letters. PMID 29944383 DOI: 10.1021/Acs.Orglett.8B01483 |
0.386 |
|
2018 |
Dalziel ME, Deichert JA, Carrera DE, Beaudry D, Han C, Zhang H, Angelaud R. Magnesium Ethoxide Promoted Conversion of Nitriles to Amidines and Its Application in 5,6-Dihydroimidazobenzoxazepine Synthesis. Organic Letters. PMID 29687714 DOI: 10.1021/Acs.Orglett.8B00824 |
0.38 |
|
2018 |
Lim NK, Cravillion T, Savage S, McClory A, Han C, Zhang H, DiPasquale A, Gosselin F. Synthesis of a Selective Estrogen Receptor Degrader via a Stereospecific Elimination Approach. Organic Letters. PMID 29397753 DOI: 10.1021/Acs.Orglett.8B00035 |
0.36 |
|
2018 |
Zhang H, Cravillion T, Lim N, Tian Q, Beaudry D, Defreese JL, Fettes A, James P, Linder D, Malhotra S, Han C, Angelaud R, Gosselin F. Development of an Efficient Manufacturing Process for Reversible Bruton’s Tyrosine Kinase Inhibitor GDC-0853 Organic Process Research & Development. 22: 978-990. DOI: 10.1021/Acs.Oprd.8B00134 |
0.363 |
|
2018 |
Han C, Green K, Oehring K, Meili A, Pfeifer E, Scalone M, Gosselin F. An Efficient Through-Process for Chk1 Kinase Inhibitor GDC-0575 Organic Process Research & Development. 22: 344-350. DOI: 10.1021/Acs.Oprd.7B00388 |
0.35 |
|
2017 |
Han C, Savage S, Al-Sayah M, Yajima H, Remarchuk T, Reents R, Wirz B, Iding H, Bachmann S, Fantasia SM, Scalone M, Hell A, Hidber P, Gosselin F. Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib. Organic Letters. PMID 28858516 DOI: 10.1021/Acs.Orglett.7B02228 |
0.41 |
|
2017 |
Li BX, Le DN, Mack KA, McClory A, Lim NK, Cravillion T, Savage S, Han C, Collum DB, Zhang H, Gosselin F. Highly Stereoselective Synthesis of Tetrasubstituted Acyclic All-carbon Olefins via Enol Tosylation and Suzuki‒Miyaura Coupling. Journal of the American Chemical Society. PMID 28715208 DOI: 10.1021/Jacs.7B05071 |
0.425 |
|
2017 |
Kelly SM, Han C, Tung L, Gosselin F. Chemoselective Copper-Catalyzed Ullmann-Type Coupling of Oxazolidinones with Bromoiodoarenes. Organic Letters. PMID 28530104 DOI: 10.1021/Acs.Orglett.7B01304 |
0.402 |
|
2017 |
Han C, Green K, Pfeifer E, Gosselin F. Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole Organic Process Research & Development. 21: 664-668. DOI: 10.1021/Acs.Oprd.7B00060 |
0.413 |
|
2016 |
Pushkarskaya E, Wong B, Han C, Capomolla S, Gu C, Stoltz BM, Zhang H. Single-step synthesis of 3-hydroxycarbazoles by annulation of electron-rich anilines and quinones Tetrahedron Letters. 57: 5653-5657. DOI: 10.1016/J.Tetlet.2016.11.009 |
0.332 |
|
2015 |
Shvartzvald Y, Udalski A, Gould A, Han C, Bozza V, Friedmann M, Hundertmark M, Beichman C, Bryden G, Novati SC, Carey S, Fausnaugh M, Gaudi BS, Henderson CB, Kerr T, et al. SPITZER MICROLENS MEASUREMENT of A MASSIVE REMNANT in A WELL-SEPARATED BINARY Astrophysical Journal. 814. DOI: 10.1088/0004-637X/814/2/111 |
0.387 |
|
2014 |
Yang Y, Niedermann K, Han C, Buchwald SL. Highly selective palladium-catalyzed cross-coupling of secondary alkylzinc reagents with heteroaryl halides. Organic Letters. 16: 4638-41. PMID 25153332 DOI: 10.1021/Ol502230P |
0.504 |
|
2009 |
Han C, Buchwald SL. Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides. Journal of the American Chemical Society. 131: 7532-3. PMID 19441851 DOI: 10.1021/Ja902046M |
0.51 |
|
2009 |
Han C, Rangarajan S, Voukides AC, Beeler AB, Johnson R, Porco JA. Reaction discovery employing macrocycles: transannular cyclizations of macrocyclic bis-lactams. Organic Letters. 11: 413-6. PMID 19102683 DOI: 10.1021/Ol802729F |
0.606 |
|
2007 |
Han C, Porco JA. Synthesis of carbamates and ureas using Zr(IV)-catalyzed exchange processes. Organic Letters. 9: 1517-20. PMID 17358074 DOI: 10.1021/ol0702728 |
0.551 |
|
2005 |
Han C, Lee JP, Lobkovsky E, Porco JA. Catalytic ester-amide exchange using group (IV) metal alkoxide-activator complexes. Journal of the American Chemical Society. 127: 10039-44. PMID 16011366 DOI: 10.1021/Ja0527976 |
0.55 |
|
2004 |
Han C, Shen R, Su S, Porco JA. Copper-mediated synthesis of N-acyl vinylogous carbamic acids and derivatives: synthesis of the antibiotic CJ-15,801. Organic Letters. 6: 27-30. PMID 14703342 DOI: 10.1021/Ol0360041 |
0.633 |
|
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