Year |
Citation |
Score |
2008 |
Rakus JF, Fedorov AA, Fedorov EV, Glasner ME, Hubbard BK, Delli JD, Babbitt PC, Almo SC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase Biochemistry. 47: 9944-9954. PMID 18754693 DOI: 10.1021/Bi800914R |
0.582 |
|
2002 |
Pootoolal J, Thomas MG, Marshall CG, Neu JM, Hubbard BK, Walsh CT, Wright GD. Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. Proceedings of the National Academy of Sciences of the United States of America. 99: 8962-7. PMID 12060705 DOI: 10.1073/Pnas.102285099 |
0.364 |
|
2002 |
Chen H, Hubbard BK, O'Connor SE, Walsh CT. Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics. Chemistry & Biology. 9: 103-12. PMID 11841943 DOI: 10.1016/S1074-5521(02)00090-X |
0.494 |
|
2001 |
Chen H, Tseng CC, Hubbard BK, Walsh CT. Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine. Proceedings of the National Academy of Sciences of the United States of America. 98: 14901-6. PMID 11752437 DOI: 10.1073/Pnas.221582098 |
0.407 |
|
2001 |
Schmidt DMZ, Hubbard BK, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: Functional assignment of unknown proteins in bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases Biochemistry. 40: 15707-15715. PMID 11747447 DOI: 10.1021/Bi011640X |
0.676 |
|
2001 |
Walsh CT, Chen H, Keating TA, Hubbard BK, Losey HC, Luo L, Marshall CG, Miller DA, Patel HM. Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines. Current Opinion in Chemical Biology. 5: 525-34. PMID 11578925 DOI: 10.1016/S1367-5931(00)00235-0 |
0.304 |
|
2001 |
Chen H, Thomas MG, O'Connor SE, Hubbard BK, Burkart MD, Walsh CT. Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics. Biochemistry. 40: 11651-9. PMID 11570865 DOI: 10.1021/Bi0115434 |
0.399 |
|
2001 |
Gulick AM, Hubbard BK, Gerlt JA, Rayment I. Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli. Biochemistry. 40: 10054-62. PMID 11513584 DOI: 10.1021/Bi010733B |
0.643 |
|
2001 |
Chiu HT, Hubbard BK, Shah AN, Eide J, Fredenburg RA, Walsh CT, Khosla C. Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 98: 8548-53. PMID 11447274 DOI: 10.1073/Pnas.151246498 |
0.352 |
|
2000 |
Hubbard BK, Thomas MG, Walsh CT. Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics. Chemistry & Biology. 7: 931-42. PMID 11137816 DOI: 10.1016/S1074-5521(00)00043-0 |
0.381 |
|
2000 |
Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD. Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11942-7. PMID 11035791 DOI: 10.1073/Pnas.210395097 |
0.476 |
|
2000 |
Gulick AM, Hubbard BK, Gerlt JA, Rayment I. Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli. Biochemistry. 39: 4590-602. PMID 10769114 DOI: 10.1021/Bi992782I |
0.672 |
|
1998 |
Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Biochemistry. 37: 14369-75. PMID 9772162 DOI: 10.1021/Bi981124F |
0.6 |
|
1998 |
Palmer DR, Hubbard BK, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: partitioning of reactive intermediates by (D)-glucarate dehydratase from Pseudomonas putida. Biochemistry. 37: 14350-7. PMID 9772160 DOI: 10.1021/Bi981122V |
0.646 |
|
1997 |
Palmer DRJ, Wieczorek SJ, Hubbard BK, Mrachko GT, Gerlt JA. Importance of mechanistic imperatives in enzyme-catalyzed β-elimination reactions: Stereochemical consequences of the dehydration reactions catalyzed by D-galactonate dehydratase from Escherichia coli and D-glucarate dehydratase from Pseudomonas putida Journal of the American Chemical Society. 119: 9580-9581. DOI: 10.1021/Ja970977C |
0.589 |
|
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