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Kevin P. McCusker, Ph.D. - Publications

Affiliations: 
2009 University of California, Berkeley, Berkeley, CA, United States 
Area:
fundamental aspects of enzyme catalysis
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. Journal of the American Chemical Society. 134: 18074-81. PMID 23088750 DOI: 10.1021/Ja307855D  0.567
2012 McCusker KP, Fujimori DG. The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. Acs Chemical Biology. 7: 64-72. PMID 22208312 DOI: 10.1021/Cb200418F  0.525
2010 McCusker KP, Klinman JP. An active-site phenylalanine directs substrate binding and C-H cleavage in the α-ketoglutarate-dependent dioxygenase AauD Journal of the American Chemical Society. 132: 5114-5120. PMID 20302299 DOI: 10.1021/Ja909416Z  0.522
2009 McCusker KP, Klinman JP. Modular behavior of tauD provides insight into the origin of specificity in α-ketoglutarate-dependent nonheme iron oxygenases Proceedings of the National Academy of Sciences of the United States of America. 106: 19791-19795. PMID 19892731 DOI: 10.1073/Pnas.0910660106  0.558
2009 McCusker KP, Klinman JP. Facile synthesis of 1,1-[2H2]-2-methylaminoethane-1-sulfonic acid as a substrate for taurine α ketoglutarate dioxygenase (TauD) Tetrahedron Letters. 50: 611-613. DOI: 10.1016/J.Tetlet.2008.11.063  0.521
2008 Mirica LM, McCusker KP, Munos JW, Liu HW, Klinman JP. 18O kinetic isotope effects in non-heme iron enzymes: probing the nature of Fe/O2 intermediates. Journal of the American Chemical Society. 130: 8122-3. PMID 18540575 DOI: 10.1021/Ja800265S  0.571
2006 Thrower J, Mirica LM, McCusker KP, Klinman JP. Mechanistic investigations of 1-aminocyclopropane 1-carboxylic acid oxidase with alternate cyclic and acyclic substrates. Biochemistry. 45: 13108-17. PMID 17059228 DOI: 10.1021/Bi061097Q  0.594
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