| Year |
Citation |
Score |
| 2023 |
Bishop AC, Serbina A. Targeting Nonconserved and Pathogenic Cysteines of Protein Tyrosine Phosphatases with Small Molecules. Methods in Molecular Biology (Clifton, N.J.). 2743: 271-283. PMID 38147221 DOI: 10.1007/978-1-0716-3569-8_17 |
0.422 |
|
| 2022 |
Buck SJS, Plaman BA, Bishop AC. Inhibition of SHP2 and SHP1 Protein Tyrosine Phosphatase Activity by Chemically Induced Dimerization. Acs Omega. 7: 14180-14188. PMID 35559188 DOI: 10.1021/acsomega.2c00780 |
0.399 |
|
| 2020 |
Kim JY, Plaman B, Bishop AC. Targeting a Pathogenic Cysteine Mutation: Discovery of a Specific Inhibitor of Y279C SHP2. Biochemistry. PMID 32871078 DOI: 10.1021/Acs.Biochem.0C00471 |
0.444 |
|
| 2019 |
Plaman BA, Chan WC, Bishop AC. Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals. Scientific Reports. 9: 16148. PMID 31695052 DOI: 10.1038/S41598-019-52002-1 |
0.512 |
|
| 2018 |
Marsh-Armstrong B, Fajnzylber JM, Korntner S, Plaman BA, Bishop AC. The Allosteric Site on SHP2's Protein Tyrosine Phosphatase Domain is Targetable with Druglike Small Molecules. Acs Omega. 3: 15763-15770. PMID 30533581 DOI: 10.1021/acsomega.8b02200 |
0.372 |
|
| 2018 |
Korntner S, Pomorski A, Krężel A, Bishop AC. Optimized allosteric inhibition of engineered protein tyrosine phosphatases with an expanded palette of biarsenical small molecules. Bioorganic & Medicinal Chemistry. PMID 29673715 DOI: 10.1016/J.Bmc.2018.04.026 |
0.515 |
|
| 2017 |
Chan WC, Knowlton GS, Bishop AC. Activation of engineered protein tyrosine phosphatases with the biarsenical compound AsCy3-EDT2. Chembiochem : a European Journal of Chemical Biology. PMID 28745017 DOI: 10.1002/Cbic.201700253 |
0.471 |
|
| 2016 |
Bishop AC. A missense methionine mutation augments catalytic activity but reduces thermal stability in two protein tyrosine phosphatases. Biochemical and Biophysical Research Communications. PMID 27816449 DOI: 10.1016/J.Bbrc.2016.11.001 |
0.336 |
|
| 2015 |
Chio CM, Cheng KW, Bishop AC. Direct Chemical Activation of a Rationally Engineered Signaling Enzyme. Chembiochem : a European Journal of Chemical Biology. 16: 1735-9. PMID 26063205 DOI: 10.1002/Cbic.201500245 |
0.401 |
|
| 2015 |
Chio CM, Yu X, Bishop AC. Rational design of allosteric-inhibition sites in classical protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry. 23: 2828-38. PMID 25828055 DOI: 10.1016/J.Bmc.2015.03.027 |
0.518 |
|
| 2015 |
Chio CM, Lim CS, Bishop AC. Targeting a cryptic allosteric site for selective inhibition of the oncogenic protein tyrosine phosphatase Shp2. Biochemistry. 54: 497-504. PMID 25519989 DOI: 10.1021/Bi5013595 |
0.481 |
|
| 2015 |
Pomorski A, Adamczyk J, Bishop AC, Krężel A. Probing the target-specific inhibition of sensitized protein tyrosine phosphatases with biarsenical probes. Organic & Biomolecular Chemistry. 13: 1395-403. PMID 25460004 DOI: 10.1039/C4Ob02256D |
0.483 |
|
| 2013 |
Harris LK, Frumm SM, Bishop AC. A general assay for monitoring the activities of protein tyrosine phosphatases in living eukaryotic cells. Analytical Biochemistry. 435: 99-105. PMID 23333221 DOI: 10.1016/J.Ab.2012.12.025 |
0.544 |
|
| 2012 |
Davis OB, Bishop AC. Specific inhibition of sensitized protein tyrosine phosphatase 1B (PTP1B) with a biarsenical probe. Bioconjugate Chemistry. 23: 272-8. PMID 22263876 DOI: 10.1021/bc200562y |
0.44 |
|
| 2010 |
Walton ZE, Bishop AC. Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activity. Bioorganic & Medicinal Chemistry. 18: 4884-91. PMID 20594861 DOI: 10.1016/J.Bmc.2010.06.022 |
0.539 |
|
| 2010 |
Chen VL, Bishop AC. Chemical rescue of protein tyrosine phosphatase activity. Chemical Communications (Cambridge, England). 46: 637-9. PMID 20062887 DOI: 10.1039/B919815F |
0.479 |
|
| 2010 |
BISHOP AC, MOORE D, SCANLAN TS, SHOKAT KM. ChemInform Abstract: Screening a Hydroxystilbene Library for Selective Inhibition of the B Cell Antigen Receptor Kinase Cascade. Cheminform. 28: no-no. DOI: 10.1002/chin.199750103 |
0.56 |
|
| 2009 |
Bishop AC, Chen VL. Brought to life: targeted activation of enzyme function with small molecules. Journal of Chemical Biology. 2: 1-9. PMID 19568788 DOI: 10.1007/S12154-008-0012-4 |
0.384 |
|
| 2008 |
Zhang XY, Chen VL, Rosen MS, Blair ER, Lone AM, Bishop AC. Allele-specific inhibition of divergent protein tyrosine phosphatases with a single small molecule. Bioorganic & Medicinal Chemistry. 16: 8090-7. PMID 18678493 DOI: 10.1016/J.Bmc.2008.07.053 |
0.544 |
|
| 2008 |
Zhang XY, Bishop AC. Engineered inhibitor sensitivity in the WPD loop of a protein tyrosine phosphatase. Biochemistry. 47: 4491-500. PMID 18358001 DOI: 10.1021/Bi800014C |
0.515 |
|
| 2007 |
Bishop AC, Zhang XY, Lone AM. Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations. Methods (San Diego, Calif.). 42: 278-88. PMID 17532515 DOI: 10.1016/J.Ymeth.2007.02.005 |
0.599 |
|
| 2007 |
Zhang XY, Bishop AC. Site-specific incorporation of allosteric-inhibition sites in a protein tyrosine phosphatase. Journal of the American Chemical Society. 129: 3812-3. PMID 17346049 DOI: 10.1021/Ja069098T |
0.474 |
|
| 2006 |
Bishop AC, Blair ER. A gatekeeper residue for inhibitor sensitization of protein tyrosine phosphatases. Bioorganic & Medicinal Chemistry Letters. 16: 4002-6. PMID 16716588 DOI: 10.1016/J.Bmcl.2006.05.011 |
0.558 |
|
| 2006 |
Blair ER, Hoffman HE, Bishop AC. Engineering non-natural inhibitor sensitivity in protein tyrosine phosphatase H1. Bioorganic & Medicinal Chemistry. 14: 464-71. PMID 16182535 DOI: 10.1016/J.Bmc.2005.08.025 |
0.592 |
|
| 2005 |
Hoffman HE, Blair ER, Johndrow JE, Bishop AC. Allele-specific inhibitors of protein tyrosine phosphatases. Journal of the American Chemical Society. 127: 2824-5. PMID 15740097 DOI: 10.1021/Ja043378W |
0.582 |
|
| 2004 |
Kunkel EJ, Plavec I, Nguyen D, Melrose J, Rosler ES, Kao LT, Wang Y, Hytopoulos E, Bishop AC, Bateman R, Shokat KM, Butcher EC, Berg EL. Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models. Assay and Drug Development Technologies. 2: 431-41. PMID 15357924 DOI: 10.1089/Adt.2004.2.431 |
0.809 |
|
| 2004 |
Bishop AC. A hot spot for protein kinase inhibitor sensitivity. Chemistry & Biology. 11: 587-9. PMID 15157868 DOI: 10.1016/J.Chembiol.2004.05.002 |
0.629 |
|
| 2003 |
Sreenivasan A, Bishop AC, Shokat KM, Kellogg DR. Specific inhibition of Elm1 kinase activity reveals functions required for early G1 events. Molecular and Cellular Biology. 23: 6327-37. PMID 12917352 DOI: 10.1128/Mcb.23.17.6327-6337.2003 |
0.664 |
|
| 2002 |
Buzko OV, Bishop AC, Shokat KM. Modified AutoDock for accurate docking of protein kinase inhibitors. Journal of Computer-Aided Molecular Design. 16: 113-27. PMID 12188021 DOI: 10.1023/A:1016366013656 |
0.826 |
|
| 2001 |
Carroll AS, Bishop AC, DeRisi JL, Shokat KM, O'Shea EK. Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response. Proceedings of the National Academy of Sciences of the United States of America. 98: 12578-83. PMID 11675494 DOI: 10.1073/Pnas.211195798 |
0.65 |
|
| 2001 |
Bishop AC, Buzko O, Shokat KM. Magic bullets for protein kinases. Trends in Cell Biology. 11: 167-72. PMID 11306297 DOI: 10.1016/S0962-8924(01)01928-6 |
0.847 |
|
| 2000 |
Liu Y, Witucki LA, Shah K, Bishop AC, Shokat KM. Src-Abl tyrosine kinase chimeras: replacement of the adenine binding pocket of c-Abl with v-Src to swap nucleotide and inhibitor specificities. Biochemistry. 39: 14400-8. PMID 11087392 DOI: 10.1021/Bi000437J |
0.822 |
|
| 2000 |
Weiss EL, Bishop AC, Shokat KM, Drubin DG. Chemical genetic analysis of the budding-yeast p21-activated kinase Cla4p. Nature Cell Biology. 2: 677-85. PMID 11025657 DOI: 10.1038/35036300 |
0.634 |
|
| 2000 |
Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 407: 395-401. PMID 11014197 DOI: 10.1038/35030148 |
0.86 |
|
| 2000 |
Bishop A, Buzko O, Heyeck-Dumas S, Jung I, Kraybill B, Liu Y, Shah K, Ulrich S, Witucki L, Yang F, Zhang C, Shokat KM. Unnatural ligands for engineered proteins: new tools for chemical genetics. Annual Review of Biophysics and Biomolecular Structure. 29: 577-606. PMID 10940260 DOI: 10.1146/Annurev.Biophys.29.1.577 |
0.679 |
|
| 2000 |
Weintraub BC, Jun JE, Bishop AC, Shokat KM, Thomas ML, Goodnow CC. Entry of B cell receptor into signaling domains is inhibited in tolerant B cells. The Journal of Experimental Medicine. 191: 1443-8. PMID 10770810 DOI: 10.1084/Jem.191.8.1443 |
0.682 |
|
| 2000 |
Armstrong JI, Portley AR, Chang YT, Nierengarten DM, Cook BN, Bowman KG, Bishop A, Gray NS, Shokat KM, Schultz PG, Bertozzi CR. Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for numerous helpful conversations. J.I.A. and K.G.B were supported by NIH Molecular Biophysics Training Grant (No. T32GM0895). This research was funded by grants to C.R.B. from the Pew Scholars Program, the W. M. Keck Foundation and the American Cancer Society (Grant No. RPG9700501BE). Angewandte Chemie (International Ed. in English). 39: 1303-1306. PMID 10767039 DOI: 10.1002/(Sici)1521-3773(20000403)39:7<1303::Aid-Anie1303>3.0.Co;2-0 |
0.616 |
|
| 1999 |
Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, Ubersax J, Blethrow J, Morgan DO, Shokat KM. Structural basis for selective inhibition of Src family kinases by PP1. Chemistry & Biology. 6: 671-8. PMID 10467133 DOI: 10.1016/S1074-5521(99)80118-5 |
0.767 |
|
| 1999 |
Bishop AC, Shokat KM. Acquisition of inhibitor-sensitive protein kinases through protein design. Pharmacology & Therapeutics. 82: 337-46. PMID 10454210 DOI: 10.1016/S0163-7258(98)00060-6 |
0.777 |
|
| 1999 |
Bishop AC, Kung CY, Shah K, Witucki L, Shokat KM, Liu Y. Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach Journal of the American Chemical Society. 121: 627-631. DOI: 10.1021/Ja983267V |
0.849 |
|
| 1998 |
Bishop AC, Shah K, Liu Y, Witucki L, Kung C, Shokat KM. Design of allele-specific inhibitors to probe protein kinase signaling. Current Biology : Cb. 8: 257-66. PMID 9501066 DOI: 10.1016/S0960-9822(98)70198-8 |
0.818 |
|
| 1998 |
Bishop AC, Moore D, Scanlan TS, Shokat KM. Corrigendum to “Screening a hydroxystilbene library for selective inhibition of the B cell antigen receptor kinase cascade” [Tetrahedron 53 (1997) 11995] Tetrahedron. 54: 1953. DOI: 10.1016/S0040-4020(97)10425-2 |
0.624 |
|
| 1997 |
Bishop AC, Moore D, Scanlan TS, Shokat KM. Screening a hydroxystilbene library for selective inhibition of the B cell antigen receptor kinase cascade Tetrahedron. 53: 11995-12004. DOI: 10.1016/S0040-4020(97)00712-6 |
0.729 |
|
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