Year |
Citation |
Score |
2023 |
D'Costa S, Hinds EC, Freschlin CR, Song H, Romero PA. Inferring protein fitness landscapes from laboratory evolution experiments. Plos Computational Biology. 19: e1010956. PMID 36857380 DOI: 10.1371/journal.pcbi.1010956 |
0.33 |
|
2020 |
Song H, Bremer BJ, Hinds EC, Raskutti G, Romero PA. Inferring Protein Sequence-Function Relationships with Large-Scale Positive-Unlabeled Learning. Cell Systems. PMID 33212013 DOI: 10.1016/j.cels.2020.10.007 |
0.31 |
|
2017 |
Ojala DS, Sun S, Santiago-Ortiz JL, Shapiro MG, Romero PA, Schaffer DV. In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28988711 DOI: 10.1016/J.Ymthe.2017.09.006 |
0.317 |
|
2015 |
Romero PA, Tran TM, Abate AR. Dissecting enzyme function with microfluidic-based deep mutational scanning. Proceedings of the National Academy of Sciences of the United States of America. 112: 7159-64. PMID 26040002 DOI: 10.1073/Pnas.1422285112 |
0.492 |
|
2013 |
Romero PA, Shapiro MG, Arnold FH, Jasanoff A. Directed evolution of protein-based neurotransmitter sensors for MRI. Methods in Molecular Biology (Clifton, N.J.). 995: 193-205. PMID 23494381 DOI: 10.1007/978-1-62703-345-9_14 |
0.516 |
|
2013 |
Heinzelman P, Romero PA, Arnold FH. Efficient sampling of SCHEMA chimera families to identify useful sequence elements. Methods in Enzymology. 523: 351-68. PMID 23422438 DOI: 10.1016/B978-0-12-394292-0.00016-3 |
0.552 |
|
2013 |
Romero PA, Krause A, Arnold FH. Navigating the protein fitness landscape with Gaussian processes. Proceedings of the National Academy of Sciences of the United States of America. 110: E193-201. PMID 23277561 DOI: 10.1073/Pnas.1215251110 |
0.591 |
|
2013 |
Smith MA, Romero PA, Wu T, Brustad EM, Arnold FH. Chimeragenesis of distantly-related proteins by noncontiguous recombination. Protein Science : a Publication of the Protein Society. 22: 231-8. PMID 23225662 DOI: 10.1002/Pro.2202 |
0.709 |
|
2012 |
Romero PA, Arnold FH. Random field model reveals structure of the protein recombinational landscape. Plos Computational Biology. 8: e1002713. PMID 23055915 DOI: 10.1371/Journal.Pcbi.1002713 |
0.621 |
|
2012 |
Komor RS, Romero PA, Xie CB, Arnold FH. Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predictive methods. Protein Engineering, Design & Selection : Peds. 25: 827-33. PMID 22961332 DOI: 10.1093/Protein/Gzs058 |
0.632 |
|
2012 |
Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis. Acs Synthetic Biology. 1: 221-8. PMID 22737599 DOI: 10.1021/Sb300014T |
0.594 |
|
2010 |
Heinzelman P, Komor R, Kanaan A, Romero P, Yu X, Mohler S, Snow C, Arnold F. Efficient screening of fungal cellobiohydrolase class i enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination Protein Engineering, Design and Selection. 23: 871-880. PMID 20847102 DOI: 10.1093/Protein/Gzq063 |
0.637 |
|
2010 |
Shapiro MG, Westmeyer GG, Romero PA, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, Jasanoff A. Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine. Nature Biotechnology. 28: 264-70. PMID 20190737 DOI: 10.1038/Nbt.1609 |
0.456 |
|
2009 |
Romero PA, Arnold FH. Exploring protein fitness landscapes by directed evolution. Nature Reviews. Molecular Cell Biology. 10: 866-76. PMID 19935669 DOI: 10.1038/Nrm2805 |
0.565 |
|
2007 |
Bloom JD, Romero PA, Lu Z, Arnold FH. Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution. Biology Direct. 2: 17. PMID 17598905 DOI: 10.1186/1745-6150-2-17 |
0.664 |
|
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