Year |
Citation |
Score |
2024 |
Nartey CM, Koo HJ, Laurendon C, Shaik HZ, O'maille P, Noel JP, Morcos F. Coevolutionary Information Captures Catalytic Functions and Reveals Divergent Roles of Terpene Synthase Interdomain Connections. Biochemistry. PMID 38206111 DOI: 10.1021/acs.biochem.3c00578 |
0.575 |
|
2023 |
Rebholz Z, Shewade L, Kaler K, Larose H, Schubot F, Tholl D, Morozov AV, O'Maille PE. Emergence of terpene chemical communication in insects: Evolutionary recruitment of isoprenoid metabolism. Protein Science : a Publication of the Protein Society. e4634. PMID 36974623 DOI: 10.1002/pro.4634 |
0.317 |
|
2023 |
Tholl D, Rebholz Z, Morozov AV, O'Maille PE. Terpene synthases and pathways in animals: enzymology and structural evolution in the biosynthesis of volatile infochemicals. Natural Product Reports. PMID 36880348 DOI: 10.1039/d2np00076h |
0.302 |
|
2020 |
Ballal A, Laurendon C, Salmon M, Vardakou M, Cheema J, Defernez M, O'Maille PE, Morozov AV. Sparse epistatic patterns in the evolution of terpene synthases. Molecular Biology and Evolution. PMID 32119077 DOI: 10.1093/Molbev/Msaa052 |
0.444 |
|
2016 |
Nguyen TD, Faraldos JA, Vardakou M, Salmon M, O'Maille PE, Ro DK. Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae. Biochemical and Biophysical Research Communications. PMID 27697527 DOI: 10.1016/J.Bbrc.2016.09.165 |
0.308 |
|
2016 |
Salmon M, Thimmappa RB, Minto RE, Melton RE, Hughes RK, O'Maille PE, Hemmings AM, Osbourn A. A conserved amino acid residue critical for product and substrate specificity in plant triterpene synthases. Proceedings of the National Academy of Sciences of the United States of America. PMID 27412861 DOI: 10.1073/pnas.1605509113 |
0.34 |
|
2016 |
Koo HJ, Vickery CR, Xu Y, Louie GV, O'Maille PE, Bowman M, Nartey CM, Burkart MD, Noel JP. Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. The Journal of Antibiotics. PMID 27328867 DOI: 10.1038/Ja.2016.68 |
0.559 |
|
2015 |
Salmon M, Laurendon C, Vardakou M, Cheema J, Defernez M, Green S, Faraldos JA, O'Maille PE. Emergence of terpene cyclization in Artemisia annua. Nature Communications. 6: 6143. PMID 25644758 DOI: 10.1038/Ncomms7143 |
0.403 |
|
2014 |
Thimmappa R, Geisler K, Louveau T, O'Maille P, Osbourn A. Triterpene biosynthesis in plants Annual Review of Plant Biology. 65: 225-257. PMID 24498976 DOI: 10.1146/Annurev-Arplant-050312-120229 |
0.31 |
|
2013 |
Crenshaw C, Aljadeff J, Fernandez I, Laurendon C, Defernez M, Koo H, O'Maille P, Sharpee T, Noel J. Protein Epistasis and the Biophysical Constraints on Catalytic Promiscuity Planta Medica. 79. DOI: 10.1055/S-0033-1348500 |
0.506 |
|
2012 |
Dokarry M, Laurendon C, O'Maille PE. Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases. Methods in Enzymology. 515: 21-42. PMID 22999168 DOI: 10.1016/B978-0-12-394290-6.00002-1 |
0.392 |
|
2012 |
Garrett SR, Morris RJ, O'Maille PE. Steady-state kinetic characterization of sesquiterpene synthases by gas chromatography-mass spectroscopy. Methods in Enzymology. 515: 3-19. PMID 22999167 DOI: 10.1016/B978-0-12-394290-6.00001-X |
0.385 |
|
2011 |
Hess BA, Smentek L, Noel JP, O'Maille PE. Physical constraints on sesquiterpene diversity arising from cyclization of the eudesm-5-yl carbocation. Journal of the American Chemical Society. 133: 12632-41. PMID 21714557 DOI: 10.1021/Ja203342P |
0.513 |
|
2011 |
Ikezawa N, Göpfert JC, Nguyen DT, Kim SU, O'Maille PE, Spring O, Ro DK. Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism. The Journal of Biological Chemistry. 286: 21601-11. PMID 21515683 DOI: 10.1074/Jbc.M110.216804 |
0.335 |
|
2010 |
Faraldos JA, O'Maille PE, Dellas N, Noel JP, Coates RM. Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. Journal of the American Chemical Society. 132: 4281-9. PMID 20201526 DOI: 10.1021/Ja909886Q |
0.548 |
|
2010 |
Noel JP, Dellas N, Faraldos JA, Zhao M, Hess BA, Smentek L, Coates RM, O'Maille PE. Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. Acs Chemical Biology. 5: 377-92. PMID 20175559 DOI: 10.1021/Cb900295G |
0.551 |
|
2008 |
O'Maille PE, Malone A, Dellas N, Andes Hess B, Smentek L, Sheehan I, Greenhagen BT, Chappell J, Manning G, Noel JP. Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases. Nature Chemical Biology. 4: 617-23. PMID 18776889 DOI: 10.1038/Nchembio.113 |
0.575 |
|
2008 |
Austin MB, O'Maille PE, Noel JP. Evolving biosynthetic tangos negotiate mechanistic landscapes. Nature Chemical Biology. 4: 217-22. PMID 18347585 DOI: 10.1038/Nchembio0408-217 |
0.515 |
|
2007 |
Faraldos JA, Zhao Y, O'Maille PE, Noel JP, Coates RM. Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate. Chembiochem : a European Journal of Chemical Biology. 8: 1826-33. PMID 17886322 DOI: 10.1002/Cbic.200700398 |
0.52 |
|
2007 |
Takahashi S, Yeo YS, Zhao Y, O'Maille PE, Greenhagen BT, Noel JP, Coates RM, Chappell J. Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates. The Journal of Biological Chemistry. 282: 31744-54. PMID 17715131 DOI: 10.1074/Jbc.M703378200 |
0.605 |
|
2006 |
Greenhagen BT, O'Maille PE, Noel JP, Chappell J. Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases. Proceedings of the National Academy of Sciences of the United States of America. 103: 9826-31. PMID 16785438 DOI: 10.1073/Pnas.0601605103 |
0.58 |
|
2006 |
O'Maille PE, Chappell J, Noel JP. Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase. Archives of Biochemistry and Biophysics. 448: 73-82. PMID 16375847 DOI: 10.1016/J.Abb.2005.10.028 |
0.541 |
|
2006 |
Köllner TG, O'Maille PE, Gatto N, Boland W, Gershenzon J, Degenhardt J. Two pockets in the active site of maize sesquiterpene synthase TPS4 carry out sequential parts of the reaction scheme resulting in multiple products. Archives of Biochemistry and Biophysics. 448: 83-92. PMID 16297849 DOI: 10.1016/J.Abb.2005.10.011 |
0.326 |
|
2005 |
Takahashi S, Zhao Y, O'Maille PE, Greenhagen BT, Noel JP, Coates RM, Chappell J. Kinetic and molecular analysis of 5-epiaristolochene 1,3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes. The Journal of Biological Chemistry. 280: 3686-96. PMID 15522862 DOI: 10.1074/Jbc.M411870200 |
0.576 |
|
2004 |
O'Maille PE, Chappell J, Noel JP. A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases. Analytical Biochemistry. 335: 210-7. PMID 15556559 DOI: 10.1016/J.Ab.2004.09.011 |
0.486 |
|
2004 |
O'Maille PE, Tsai MD, Greenhagen BT, Chappell J, Noel JP. Gene library synthesis by structure-based combinatorial protein engineering. Methods in Enzymology. 388: 75-91. PMID 15289063 DOI: 10.1016/S0076-6879(04)88008-X |
0.635 |
|
2002 |
O'Maille PE, Bakhtina M, Tsai MD. Structure-based combinatorial protein engineering (SCOPE). Journal of Molecular Biology. 321: 677-91. PMID 12206782 DOI: 10.1016/S0022-2836(02)00675-7 |
0.52 |
|
1999 |
Li J, Byeon IJ, Ericson K, Poi MJ, O'Maille P, Selby T, Tsai MD. Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A. Biochemistry. 38: 2930-40. PMID 10074345 DOI: 10.1021/Bi982286E |
0.653 |
|
1998 |
Byeon IJ, Li J, Ericson K, Selby TL, Tevelev A, Kim HJ, O'Maille P, Tsai MD. Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4. Molecular Cell. 1: 421-31. PMID 9660926 DOI: 10.1016/S1097-2765(00)80042-8 |
0.641 |
|
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