Year |
Citation |
Score |
2018 |
Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE. Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in . Proceedings of the National Academy of Sciences of the United States of America. PMID 30061394 DOI: 10.1073/Pnas.1801117115 |
0.386 |
|
2015 |
Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice. Neuron. 85: 726-41. PMID 25661181 DOI: 10.1016/J.Neuron.2015.01.008 |
0.425 |
|
2014 |
Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, et al. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease. Science Translational Medicine. 6: 268ra178. PMID 25540325 DOI: 10.1126/Scitranslmed.3010523 |
0.493 |
|
2014 |
Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease. Nature Medicine. 20: 536-41. PMID 24784230 DOI: 10.1038/Nm.3514 |
0.469 |
|
2012 |
Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 75: 41-57. PMID 22794259 DOI: 10.1016/J.Neuron.2012.05.024 |
0.424 |
|
2011 |
Greiner ER, Yang XW. Huntington's disease: flipping a switch on huntingtin. Nature Chemical Biology. 7: 412-4. PMID 21685885 DOI: 10.1038/Nchembio.604 |
0.364 |
|
2011 |
Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice. Neuron. 70: 427-40. PMID 21555070 DOI: 10.1016/J.Neuron.2011.03.021 |
0.432 |
|
2009 |
Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron. 64: 828-40. PMID 20064390 DOI: 10.1016/J.Neuron.2009.11.020 |
0.469 |
|
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