Year |
Citation |
Score |
2020 |
Carrasco-López C, García-Echauri SA, Kichuk T, Avalos JL. Optogenetics and biosensors set the stage for metabolic cybergenetics. Current Opinion in Biotechnology. 65: 296-309. PMID 32932048 DOI: 10.1016/J.Copbio.2020.07.012 |
0.314 |
|
2020 |
Lalwani MA, Ip SS, Carrasco-López C, Day C, Zhao EM, Kawabe H, Avalos JL. Optogenetic control of the lac operon for bacterial chemical and protein production. Nature Chemical Biology. PMID 32895498 DOI: 10.1038/S41589-020-0639-1 |
0.339 |
|
2020 |
Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, Goglia AG, Avalos JL, Toettcher JE. Optogenetic control of protein binding using light-switchable nanobodies. Nature Communications. 11: 4044. PMID 32792536 DOI: 10.1038/S41467-020-17836-8 |
0.347 |
|
2020 |
Carrasco-López C, Zhao EM, Gil AA, Alam N, Toettcher JE, Avalos JL. Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold. Nature Communications. 11: 4045. PMID 32792484 DOI: 10.1038/S41467-020-17837-7 |
0.322 |
|
2020 |
Kichuk TC, Carrasco-López C, Avalos JL. Lights up on organelles: Optogenetic tools to control subcellular structure and organization. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1500. PMID 32715616 DOI: 10.1002/Wsbm.1500 |
0.311 |
|
2020 |
Duran L, López JM, Avalos JL. ¡Viva la Mitochondria!: Harnessing yeast mitochondria for chemical production. Fems Yeast Research. PMID 32592388 DOI: 10.1093/Femsyr/Foaa037 |
0.353 |
|
2020 |
Hammer SK, Zhang Y, Avalos JL. Mitochondrial compartmentalization confers specificity to the 2-ketoacid recursive pathway: increasing isopentanol production in Saccharomyces cerevisiae. Acs Synthetic Biology. PMID 32049515 DOI: 10.1021/Acssynbio.9B00420 |
0.376 |
|
2019 |
Kuroda K, Hammer SK, Watanabe Y, Montaño López J, Fink GR, Stephanopoulos G, Ueda M, Avalos JL. Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast. Cell Systems. PMID 31734159 DOI: 10.1016/J.Cels.2019.10.006 |
0.347 |
|
2019 |
Zhang Y, Lane S, Chen JM, Hammer SK, Luttinger J, Yang L, Jin YS, Avalos JL. Xylose utilization stimulates mitochondrial production of isobutanol and 2-methyl-1-butanol in . Biotechnology For Biofuels. 12: 223. PMID 31548865 DOI: 10.1186/S13068-019-1560-2 |
0.302 |
|
2019 |
Zhao EM, Suek N, Wilson MZ, Dine E, Pannucci NL, Gitai Z, Avalos JL, Toettcher JE. Light-based control of metabolic flux through assembly of synthetic organelles. Nature Chemical Biology. PMID 31086330 DOI: 10.1038/S41589-019-0284-8 |
0.402 |
|
2018 |
Lalwani MA, Zhao EM, Avalos JL. Current and future modalities of dynamic control in metabolic engineering. Current Opinion in Biotechnology. 52: 56-65. PMID 29574344 DOI: 10.1016/J.Copbio.2018.02.007 |
0.312 |
|
2018 |
Zhao EM, Zhang Y, Mehl J, Park H, Lalwani MA, Toettcher JE, Avalos JL. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature. PMID 29562237 DOI: 10.1038/Nature26141 |
0.36 |
|
2017 |
Hammer SK, Avalos JL. Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis. Metabolic Engineering. PMID 29037781 DOI: 10.1016/J.Ymben.2017.10.001 |
0.344 |
|
2017 |
Hammer SK, Avalos JL. Harnessing yeast organelles for metabolic engineering. Nature Chemical Biology. 13: 823-832. PMID 28853733 DOI: 10.1038/Nchembio.2429 |
0.347 |
|
2016 |
Hammer SK, Avalos JL. Metabolic engineering: Biosensors get the green light. Nature Chemical Biology. 12: 894-895. PMID 27755525 DOI: 10.1038/Nchembio.2214 |
0.35 |
|
2013 |
Avalos JL, Fink GR, Stephanopoulos G. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nature Biotechnology. 31: 335-41. PMID 23417095 DOI: 10.1038/Nbt.2509 |
0.408 |
|
2006 |
Hoff KG, Avalos JL, Sens K, Wolberger C. Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide. Structure (London, England : 1993). 14: 1231-40. PMID 16905097 DOI: 10.1016/J.Str.2006.06.006 |
0.626 |
|
2006 |
Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. The structural basis of sirtuin substrate affinity. Biochemistry. 45: 7511-21. PMID 16768447 DOI: 10.1021/Bi0526332 |
0.62 |
|
2006 |
Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. On the Structural Basis of Sirtuin Substrate Affinity Biochemistry. 45: 7511-7521. DOI: 10.2210/Pdb2H2D/Pdb |
0.59 |
|
2005 |
Avalos JL, Bever KM, Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Molecular Cell. 17: 855-68. PMID 15780941 DOI: 10.1016/J.Molcel.2005.02.022 |
0.638 |
|
2004 |
Avalos JL, Boeke JD, Wolberger C. Structural basis for the mechanism and regulation of Sir2 enzymes. Molecular Cell. 13: 639-48. PMID 15023335 DOI: 10.1016/S1097-2765(04)00082-6 |
0.662 |
|
2002 |
Avalos JL, Celic I, Muhammad S, Cosgrove MS, Boeke JD, Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Molecular Cell. 10: 523-35. PMID 12408821 DOI: 10.1016/S1097-2765(02)00628-7 |
0.64 |
|
2002 |
Smith JS, Avalos J, Celic I, Muhammad S, Wolberger C, Boeke JD. SIR2 family of NAD(+)-dependent protein deacetylases. Methods in Enzymology. 353: 282-300. PMID 12078503 DOI: 10.1016/S0076-6879(02)53056-1 |
0.543 |
|
2001 |
Sauve AA, Celic I, Avalos J, Deng H, Boeke JD, Schramm VL. Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions. Biochemistry. 40: 15456-63. PMID 11747420 DOI: 10.1021/Bi011858J |
0.373 |
|
2000 |
Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proceedings of the National Academy of Sciences of the United States of America. 97: 6658-63. PMID 10841563 DOI: 10.1073/Pnas.97.12.6658 |
0.595 |
|
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