Jose L. Avalos, Ph.D. - Publications

Affiliations: 
2004 Johns Hopkins University, Baltimore, MD 
Area:
lysine ubiquitination and acetylation, using x-ray crystallography, together with biochemical, biophysical and genetic analysis

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Carrasco-López C, García-Echauri SA, Kichuk T, Avalos JL. Optogenetics and biosensors set the stage for metabolic cybergenetics. Current Opinion in Biotechnology. 65: 296-309. PMID 32932048 DOI: 10.1016/J.Copbio.2020.07.012  0.314
2020 Lalwani MA, Ip SS, Carrasco-López C, Day C, Zhao EM, Kawabe H, Avalos JL. Optogenetic control of the lac operon for bacterial chemical and protein production. Nature Chemical Biology. PMID 32895498 DOI: 10.1038/S41589-020-0639-1  0.339
2020 Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, Goglia AG, Avalos JL, Toettcher JE. Optogenetic control of protein binding using light-switchable nanobodies. Nature Communications. 11: 4044. PMID 32792536 DOI: 10.1038/S41467-020-17836-8  0.347
2020 Carrasco-López C, Zhao EM, Gil AA, Alam N, Toettcher JE, Avalos JL. Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold. Nature Communications. 11: 4045. PMID 32792484 DOI: 10.1038/S41467-020-17837-7  0.322
2020 Kichuk TC, Carrasco-López C, Avalos JL. Lights up on organelles: Optogenetic tools to control subcellular structure and organization. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. e1500. PMID 32715616 DOI: 10.1002/Wsbm.1500  0.311
2020 Duran L, López JM, Avalos JL. ¡Viva la Mitochondria!: Harnessing yeast mitochondria for chemical production. Fems Yeast Research. PMID 32592388 DOI: 10.1093/Femsyr/Foaa037  0.353
2020 Hammer SK, Zhang Y, Avalos JL. Mitochondrial compartmentalization confers specificity to the 2-ketoacid recursive pathway: increasing isopentanol production in Saccharomyces cerevisiae. Acs Synthetic Biology. PMID 32049515 DOI: 10.1021/Acssynbio.9B00420  0.376
2019 Kuroda K, Hammer SK, Watanabe Y, Montaño López J, Fink GR, Stephanopoulos G, Ueda M, Avalos JL. Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast. Cell Systems. PMID 31734159 DOI: 10.1016/J.Cels.2019.10.006  0.347
2019 Zhang Y, Lane S, Chen JM, Hammer SK, Luttinger J, Yang L, Jin YS, Avalos JL. Xylose utilization stimulates mitochondrial production of isobutanol and 2-methyl-1-butanol in . Biotechnology For Biofuels. 12: 223. PMID 31548865 DOI: 10.1186/S13068-019-1560-2  0.302
2019 Zhao EM, Suek N, Wilson MZ, Dine E, Pannucci NL, Gitai Z, Avalos JL, Toettcher JE. Light-based control of metabolic flux through assembly of synthetic organelles. Nature Chemical Biology. PMID 31086330 DOI: 10.1038/S41589-019-0284-8  0.402
2018 Lalwani MA, Zhao EM, Avalos JL. Current and future modalities of dynamic control in metabolic engineering. Current Opinion in Biotechnology. 52: 56-65. PMID 29574344 DOI: 10.1016/J.Copbio.2018.02.007  0.312
2018 Zhao EM, Zhang Y, Mehl J, Park H, Lalwani MA, Toettcher JE, Avalos JL. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature. PMID 29562237 DOI: 10.1038/Nature26141  0.36
2017 Hammer SK, Avalos JL. Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis. Metabolic Engineering. PMID 29037781 DOI: 10.1016/J.Ymben.2017.10.001  0.344
2017 Hammer SK, Avalos JL. Harnessing yeast organelles for metabolic engineering. Nature Chemical Biology. 13: 823-832. PMID 28853733 DOI: 10.1038/Nchembio.2429  0.347
2016 Hammer SK, Avalos JL. Metabolic engineering: Biosensors get the green light. Nature Chemical Biology. 12: 894-895. PMID 27755525 DOI: 10.1038/Nchembio.2214  0.35
2013 Avalos JL, Fink GR, Stephanopoulos G. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nature Biotechnology. 31: 335-41. PMID 23417095 DOI: 10.1038/Nbt.2509  0.408
2006 Hoff KG, Avalos JL, Sens K, Wolberger C. Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide. Structure (London, England : 1993). 14: 1231-40. PMID 16905097 DOI: 10.1016/J.Str.2006.06.006  0.626
2006 Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. The structural basis of sirtuin substrate affinity. Biochemistry. 45: 7511-21. PMID 16768447 DOI: 10.1021/Bi0526332  0.62
2006 Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. On the Structural Basis of Sirtuin Substrate Affinity Biochemistry. 45: 7511-7521. DOI: 10.2210/Pdb2H2D/Pdb  0.59
2005 Avalos JL, Bever KM, Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Molecular Cell. 17: 855-68. PMID 15780941 DOI: 10.1016/J.Molcel.2005.02.022  0.638
2004 Avalos JL, Boeke JD, Wolberger C. Structural basis for the mechanism and regulation of Sir2 enzymes. Molecular Cell. 13: 639-48. PMID 15023335 DOI: 10.1016/S1097-2765(04)00082-6  0.662
2002 Avalos JL, Celic I, Muhammad S, Cosgrove MS, Boeke JD, Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Molecular Cell. 10: 523-35. PMID 12408821 DOI: 10.1016/S1097-2765(02)00628-7  0.64
2002 Smith JS, Avalos J, Celic I, Muhammad S, Wolberger C, Boeke JD. SIR2 family of NAD(+)-dependent protein deacetylases. Methods in Enzymology. 353: 282-300. PMID 12078503 DOI: 10.1016/S0076-6879(02)53056-1  0.543
2001 Sauve AA, Celic I, Avalos J, Deng H, Boeke JD, Schramm VL. Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions. Biochemistry. 40: 15456-63. PMID 11747420 DOI: 10.1021/Bi011858J  0.373
2000 Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proceedings of the National Academy of Sciences of the United States of America. 97: 6658-63. PMID 10841563 DOI: 10.1073/Pnas.97.12.6658  0.595
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