| Year |
Citation |
Score |
| 2024 |
Byrns CN, Perlegos AE, Miller KN, Jin Z, Carranza FR, Manchandra P, Beveridge CH, Randolph CE, Chaluvadi VS, Zhang SL, Srinivasan AR, Bennett FC, Sehgal A, Adams PD, Chopra G, ... Bonini NM, et al. Author Correction: Senescent glia link mitochondrial dysfunction and lipid accumulation. Nature. PMID 39112716 DOI: 10.1038/s41586-024-07904-0 |
0.344 |
|
| 2024 |
Byrns CN, Perlegos AE, Miller KN, Jin Z, Carranza FR, Manchandra P, Beveridge CH, Randolph CE, Chaluvadi VS, Zhang SL, Srinivasan AR, Bennett FC, Sehgal A, Adams PD, Chopra G, ... Bonini NM, et al. Senescent glia link mitochondrial dysfunction and lipid accumulation. Nature. PMID 38839958 DOI: 10.1038/s41586-024-07516-8 |
0.427 |
|
| 2023 |
Goodman LD, Prudencio M, Kramer NJ, Martinez-Ramirez LF, Srinivasan AR, Lan M, Parisi MJ, Zhu Y, Chew J, Cook CN, Berson A, Gitler AD, Petrucelli L, Bonini NM. Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience. 26: 528. PMID 36810653 DOI: 10.1038/s41593-023-01274-y |
0.734 |
|
| 2021 |
McGurk L, Rifai OM, Shcherbakova O, Perlegos AE, Byrns CN, Carranza FR, Zhou HW, Kim HJ, Zhu Y, Bonini NM. Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence. Human Molecular Genetics. PMID 34077532 DOI: 10.1093/hmg/ddab148 |
0.329 |
|
| 2020 |
McGurk L, Rifai O, Bonini NM. TDP-43 a protein central to amyotrophic lateral sclerosis is destabilized by Tankyrase-1/2. Journal of Cell Science. PMID 32409565 DOI: 10.1242/jcs.245811 |
0.442 |
|
| 2019 |
Goodman LD, Bonini NM. New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. Trends in Genetics : Tig. PMID 31837826 DOI: 10.1016/j.tig.2019.11.003 |
0.738 |
|
| 2019 |
Goodman LD, Bonini NM. Repeat-associated non-AUG (RAN) translation mechanisms running into focus for GGGGCC-repeat associated ALS/FTD. Progress in Neurobiology. 101697. PMID 31550516 DOI: 10.1016/J.Pneurobio.2019.101697 |
0.75 |
|
| 2019 |
McGurk L, Rifai OM, Bonini NM. Poly(ADP-Ribosylation) in Age-Related Neurological Disease. Trends in Genetics : Tig. PMID 31182245 DOI: 10.1016/j.tig.2019.05.004 |
0.455 |
|
| 2019 |
Goodman LD, Prudencio M, Kramer NJ, Martinez-Ramirez LF, Srinivasan AR, Lan M, Parisi MJ, Zhu Y, Chew J, Cook CN, Berson A, Gitler AD, Petrucelli L, Bonini NM. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience. PMID 31110321 DOI: 10.1038/S41593-019-0396-1 |
0.766 |
|
| 2019 |
Berson A, Goodman LD, Sartoris AN, Otte CG, Aykit JA, Lee VM, Trojanowski JQ, Bonini NM. Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies. Acta Neuropathologica Communications. 7: 65. PMID 31036086 DOI: 10.1186/S40478-019-0710-X |
0.76 |
|
| 2019 |
Goodman LD, Prudencio M, Srinivasan AR, Rifai OM, Lee VM, Petrucelli L, Bonini NM. eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. Acta Neuropathologica Communications. 7: 62. PMID 31023341 DOI: 10.1186/S40478-019-0711-9 |
0.732 |
|
| 2018 |
McGurk L, Gomes E, Guo L, Shorter J, Bonini N. Poly(ADP-ribose) engages the TDP-43 nuclear-localization sequence to regulate granulo-filamentous aggregation. Biochemistry. PMID 30540446 DOI: 10.1021/Acs.Biochem.8B00910 |
0.559 |
|
| 2018 |
Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406. PMID 30353006 DOI: 10.1038/S41467-018-06543-0 |
0.433 |
|
| 2018 |
Kennerdell JR, Liu N, Bonini NM. MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging. Nature Communications. 9: 4188. PMID 30305625 DOI: 10.1038/S41467-018-06592-5 |
0.43 |
|
| 2018 |
McGurk L, Mojsilovic-Petrovic J, Van Deerlin VM, Shorter J, Kalb RG, Lee VM, Trojanowski JQ, Lee EB, Bonini NM. Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 6: 84. PMID 30157956 DOI: 10.1186/S40478-018-0586-1 |
0.578 |
|
| 2018 |
McGurk L, Gomes E, Guo L, Mojsilovic-Petrovic J, Tran V, Kalb RG, Shorter J, Bonini NM. Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization. Molecular Cell. PMID 30100264 DOI: 10.1016/J.Molcel.2018.07.002 |
0.541 |
|
| 2018 |
Mordes DA, Prudencio M, Goodman LD, Klim JR, Moccia R, Limone F, Pietilainen O, Chowdhary K, Dickson DW, Rademakers R, Bonini NM, Petrucelli L, Eggan K. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Acta Neuropathologica Communications. 6: 55. PMID 29973287 DOI: 10.1186/S40478-018-0555-8 |
0.743 |
|
| 2018 |
Berson A, Nativio R, Berger SL, Bonini NM. Epigenetic Regulation in Neurodegenerative Diseases. Trends in Neurosciences. PMID 29885742 DOI: 10.1016/J.Tins.2018.05.005 |
0.363 |
|
| 2018 |
Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL. Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease. Nature Neuroscience. PMID 29556027 DOI: 10.1038/S41593-018-0124-2 |
0.559 |
|
| 2018 |
Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL. Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease. Nature Neuroscience. PMID 29507413 DOI: 10.1038/S41593-018-0101-9 |
0.573 |
|
| 2017 |
Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM. TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling. Current Biology : Cb. PMID 29153328 DOI: 10.1016/J.Cub.2017.10.024 |
0.361 |
|
| 2017 |
Kim SA, D'Acunto VF, Kokona B, Hofmann J, Cunningham NR, Bistline EM, Garcia FJ, Akhtar NM, Hoffman SH, Doshi SH, Ulrich KM, Jones NM, Bonini N, Roberts CM, Link CD, et al. Sedimentation Velocity Analysis With Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila Melanogaster and Caenorhabditis Elegans. Biochemistry. PMID 28786671 DOI: 10.1021/Acs.Biochem.7B00518 |
0.35 |
|
| 2017 |
Bonini NM, Lee EB, Wasco W, Roses AD. Editorial overview: Molecular & genetic basis of disease. Current Opinion in Genetics & Development. PMID 28473186 DOI: 10.1016/J.Gde.2017.04.003 |
0.316 |
|
| 2016 |
Sproviero W, Shatunov A, Stahl D, Shoai M, van Rheenen W, Jones AR, Al-Sarraj S, Andersen PM, Bonini NM, Conforti FL, Van Damme P, Daoud H, Del Mar Amador M, Fogh I, Forzan M, et al. ATXN2 trinucleotide repeat length correlates with risk of ALS. Neurobiology of Aging. PMID 28017481 DOI: 10.1016/J.Neurobiolaging.2016.11.010 |
0.567 |
|
| 2016 |
Crowe EP, Tuzer F, Gregory BD, Donahue G, Gosai SJ, Cohen J, Leung YY, Yetkin E, Nativio R, Wang LS, Sell C, Bonini NM, Berger SL, Johnson FB, Torres C. Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence. Frontiers in Aging Neuroscience. 8: 208. PMID 27630559 DOI: 10.3389/Fnagi.2016.00208 |
0.62 |
|
| 2016 |
Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW, Goodman LD, Daughrity L, Chew J, Garrett A, ... ... Bonini NM, et al. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science (New York, N.Y.). 353: 708-12. PMID 27516603 DOI: 10.1126/Science.Aaf7791 |
0.768 |
|
| 2016 |
Perrimon N, Bonini NM, Dhillon P. Fruit flies on the front line: the translational impact of Drosophila. Disease Models & Mechanisms. 9: 229-31. PMID 26935101 DOI: 10.1242/dmm.024810 |
0.35 |
|
| 2015 |
Schweizer Burguete A, Almeida S, Gao FB, Kalb R, Akins MR, Bonini NM. GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function. Elife. 4. PMID 26650351 DOI: 10.7554/Elife.08881 |
0.365 |
|
| 2015 |
McGurk L, Berson A, Bonini NM. Drosophila as an In Vivo Model for Human Neurodegenerative Disease. Genetics. 201: 377-402. PMID 26447127 DOI: 10.1534/genetics.115.179457 |
0.384 |
|
| 2015 |
Fang Y, Bonini NM. Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury. Neural Regeneration Research. 10: 173-5. PMID 25883604 DOI: 10.4103/1673-5374.152359 |
0.3 |
|
| 2015 |
Feltzin VL, Khaladkar M, Abe M, Parisi M, Hendriks GJ, Kim J, Bonini NM. The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila. Aging Cell. 14: 443-52. PMID 25754031 DOI: 10.1111/Acel.12323 |
0.59 |
|
| 2015 |
Bonini NM, Hardiman O. Ataxin-2 expands insight into the ALS clinical spectrum. Neurology. 84: 224-5. PMID 25527266 DOI: 10.1212/Wnl.0000000000001167 |
0.346 |
|
| 2015 |
Yu Z, Goodman LD, Shieh SY, Min M, Teng X, Zhu Y, Bonini NM. A fly model for the CCUG-repeat expansion of myotonic dystrophy type 2 reveals a novel interaction with MBNL1. Human Molecular Genetics. 24: 954-62. PMID 25305073 DOI: 10.1093/Hmg/Ddu507 |
0.788 |
|
| 2015 |
Chen Q, Crowe EP, Kuhn T, Johnson JE, Gregory BD, Donahue G, Bonini NM, Berger SL, Sell C, Torres C, Brad Johnson F. Connections between cell senescence, chromatin, and neurodegeneration Experimental Gerontology. 68: 93-94. DOI: 10.1016/J.Exger.2015.01.011 |
0.548 |
|
| 2014 |
McGurk L, Lee VM, Trojanowksi JQ, Van Deerlin VM, Lee EB, Bonini NM. Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72. Journal of Neuropathology and Experimental Neurology. 73: 837-45. PMID 25111021 DOI: 10.1097/Nen.0000000000000102 |
0.392 |
|
| 2014 |
Abe M, Naqvi A, Hendriks GJ, Feltzin V, Zhu Y, Grigoriev A, Bonini NM. Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila. Genes & Development. 28: 44-57. PMID 24395246 DOI: 10.1101/Gad.226654.113 |
0.763 |
|
| 2014 |
Kim HJ, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM, Finkbeiner S, Gitler AD, Bonini NM. Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Nature Genetics. 46: 152-60. PMID 24336168 DOI: 10.1038/Ng.2853 |
0.62 |
|
| 2013 |
Cushman-Nick M, Bonini NM, Shorter J. Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model. Plos Genetics. 9: e1003781. PMID 24039611 DOI: 10.1371/Journal.Pgen.1003781 |
0.781 |
|
| 2013 |
Fang Y, Soares L, Bonini NM. Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing. Nature Protocols. 8: 810-9. PMID 23589940 DOI: 10.1038/Nprot.2013.042 |
0.304 |
|
| 2013 |
Abe M, Bonini NM. MicroRNAs and neurodegeneration: role and impact. Trends in Cell Biology. 23: 30-6. PMID 23026030 DOI: 10.1016/J.Tcb.2012.08.013 |
0.641 |
|
| 2012 |
Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, ... ... Bonini NM, et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 2899-911. PMID 22454397 DOI: 10.1093/Hmg/Dds116 |
0.726 |
|
| 2012 |
Fang Y, Soares L, Teng X, Geary M, Bonini NM. A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity. Current Biology : Cb. 22: 590-5. PMID 22425156 DOI: 10.1016/J.Cub.2012.01.065 |
0.313 |
|
| 2012 |
Liu N, Landreh M, Cao K, Abe M, Hendriks GJ, Kennerdell JR, Zhu Y, Wang LS, Bonini NM. The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature. 482: 519-23. PMID 22343898 DOI: 10.1038/Nature10810 |
0.634 |
|
| 2012 |
McGurk L, Bonini NM. Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila. Human Molecular Genetics. 21: 76-84. PMID 21949352 DOI: 10.1093/hmg/ddr439 |
0.418 |
|
| 2011 |
McGurk L, Bonini NM. Cell biology. Yeast informs Alzheimer's disease. Science (New York, N.Y.). 334: 1212-3. PMID 22144604 DOI: 10.1126/science.1216073 |
0.395 |
|
| 2011 |
Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, ... ... Bonini NM, et al. A yeast functional screen predicts new candidate ALS disease genes. Proceedings of the National Academy of Sciences of the United States of America. 108: 20881-90. PMID 22065782 DOI: 10.1073/Pnas.1109434108 |
0.717 |
|
| 2011 |
Liu N, Abe M, Sabin LR, Hendriks GJ, Naqvi AS, Yu Z, Cherry S, Bonini NM. The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila. Current Biology : Cb. 21: 1888-93. PMID 22055292 DOI: 10.1016/J.Cub.2011.10.006 |
0.77 |
|
| 2011 |
Shieh SY, Bonini NM. Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila. Human Molecular Genetics. 20: 4810-21. PMID 21933837 DOI: 10.1093/Hmg/Ddr420 |
0.751 |
|
| 2011 |
Yu Z, Bonini NM. Modeling human trinucleotide repeat diseases in Drosophila. International Review of Neurobiology. 99: 191-212. PMID 21906541 DOI: 10.1016/B978-0-12-387003-2.00008-2 |
0.439 |
|
| 2011 |
Bonini NM, Gitler AD. Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS. Journal of Molecular Neuroscience : Mn. 45: 676-83. PMID 21660502 DOI: 10.1007/S12031-011-9548-9 |
0.632 |
|
| 2011 |
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD. Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis. Neurology. 76: 2062-5. PMID 21562248 DOI: 10.1212/Wnl.0B013E31821F4447 |
0.593 |
|
| 2011 |
Yu Z, Zhu Y, Chen-Plotkin AS, Clay-Falcone D, McCluskey L, Elman L, Kalb RG, Trojanowski JQ, Lee VM, Van Deerlin VM, Gitler AD, Bonini NM. PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats. Plos One. 6: e17951. PMID 21479228 DOI: 10.1371/Journal.Pone.0017951 |
0.604 |
|
| 2011 |
Yu Z, Teng X, Bonini NM. Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy. Plos Genetics. 7: e1001340. PMID 21437269 DOI: 10.1371/journal.pgen.1001340 |
0.427 |
|
| 2011 |
Lee T, Li YR, Ingre C, Weber M, Grehl T, Gredal O, de Carvalho M, Meyer T, Tysnes OB, Auburger G, Gispert S, Bonini NM, Andersen PM, Gitler AD. Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. Human Molecular Genetics. 20: 1697-700. PMID 21292779 DOI: 10.1093/Hmg/Ddr045 |
0.586 |
|
| 2011 |
Jung J, van Jaarsveld MT, Shieh SY, Xu K, Bonini NM. Defining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogaster. Genetics. 187: 61-71. PMID 21041558 DOI: 10.1534/Genetics.110.121418 |
0.743 |
|
| 2010 |
Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, Armakola M, Geser F, Greene R, Lu MM, Padmanabhan A, Clay-Falcone D, McCluskey L, Elman L, Juhr D, ... ... Bonini NM, et al. Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature. 466: 1069-75. PMID 20740007 DOI: 10.1038/Nature09320 |
0.624 |
|
| 2010 |
Hao LY, Giasson BI, Bonini NM. DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function. Proceedings of the National Academy of Sciences of the United States of America. 107: 9747-52. PMID 20457924 DOI: 10.1073/Pnas.0911175107 |
0.3 |
|
| 2010 |
Li LB, Bonini NM. Roles of trinucleotide-repeat RNA in neurological disease and degeneration. Trends in Neurosciences. 33: 292-8. PMID 20398949 DOI: 10.1016/J.Tins.2010.03.004 |
0.585 |
|
| 2010 |
Bilen J, Bonini NM. Using Drosophila to Reveal Insight into Protein Misfolding Diseases Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 191-211. DOI: 10.1002/9780470572702.ch10 |
0.798 |
|
| 2009 |
Jung J, Xu K, Lessing D, Bonini NM. Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3. Human Molecular Genetics. 18: 4843-52. PMID 19783548 DOI: 10.1093/Hmg/Ddp456 |
0.446 |
|
| 2009 |
Lessing D, Bonini NM. Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants. Nature Reviews. Genetics. 10: 359-70. PMID 19434080 DOI: 10.1038/Nrg2563 |
0.415 |
|
| 2008 |
van der Brug MP, Blackinton J, Chandran J, Hao LY, Lal A, Mazan-Mamczarz K, Martindale J, Xie C, Ahmad R, Thomas KJ, Beilina A, Gibbs JR, Ding J, Myers AJ, Zhan M, ... ... Bonini NM, et al. RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 10244-9. PMID 18626009 DOI: 10.1073/Pnas.0708518105 |
0.386 |
|
| 2008 |
Watson MR, Lagow RD, Xu K, Zhang B, Bonini NM. A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1. The Journal of Biological Chemistry. 283: 24972-81. PMID 18596033 DOI: 10.1074/Jbc.M804817200 |
0.658 |
|
| 2008 |
Li LB, Yu Z, Teng X, Bonini NM. RNA toxicity is a component of ataxin-3 degeneration in Drosophila. Nature. 453: 1107-11. PMID 18449188 DOI: 10.1038/Nature06909 |
0.574 |
|
| 2008 |
Lessing D, Bonini NM. Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila. Plos Biology. 6: e29. PMID 18271626 DOI: 10.1371/Journal.Pbio.0060029 |
0.466 |
|
| 2007 |
Li LB, Xu K, Bonini NM. Suppression of polyglutamine toxicity by the yeast Sup35 prion domain in Drosophila. The Journal of Biological Chemistry. 282: 37694-701. PMID 17956866 DOI: 10.1074/Jbc.M705211200 |
0.546 |
|
| 2007 |
Bilen J, Bonini NM. Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila. Plos Genetics. 3: 1950-64. PMID 17953484 DOI: 10.1371/Journal.Pgen.0030177 |
0.821 |
|
| 2007 |
Jung J, Bonini N. CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease. Science (New York, N.Y.). 315: 1857-9. PMID 17332375 DOI: 10.1126/science.1139517 |
0.428 |
|
| 2006 |
Liu N, Bonini NM. Hosting neurotoxicity in polyglutamine disease. Cell. 127: 1299-300. PMID 17190592 DOI: 10.1016/J.Cell.2006.12.012 |
0.523 |
|
| 2006 |
Bilen J, Liu N, Bonini NM. A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins. Cell Cycle (Georgetown, Tex.). 5: 2835-8. PMID 17172864 DOI: 10.4161/Cc.5.24.3579 |
0.79 |
|
| 2006 |
Bilen J, Liu N, Burnett BG, Pittman RN, Bonini NM. MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Molecular Cell. 24: 157-63. PMID 17018300 DOI: 10.1016/J.Molcel.2006.07.030 |
0.788 |
|
| 2006 |
Meulener MC, Xu K, Thomson L, Thompson L, Ischiropoulos H, Bonini NM. Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. Proceedings of the National Academy of Sciences of the United States of America. 103: 12517-22. PMID 16894167 DOI: 10.1073/Pnas.0601891103 |
0.779 |
|
| 2006 |
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, ... ... Bonini NM, et al. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.). 313: 324-8. PMID 16794039 DOI: 10.1126/Science.1129462 |
0.689 |
|
| 2006 |
Boeddrich A, Gaumer S, Haacke A, Tzvetkov N, Albrecht M, Evert BO, Müller EC, Lurz R, Breuer P, Schugardt N, Plassmann S, Xu K, Warrick JM, Suopanki J, Wüllner U, ... ... Bonini NM, et al. An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. The Embo Journal. 25: 1547-58. PMID 16525503 DOI: 10.1038/sj.emboj.7601043 |
0.617 |
|
| 2006 |
Uryu K, Richter-Landsberg C, Welch W, Sun E, Goldbaum O, Norris EH, Pham CT, Yazawa I, Hilburger K, Micsenyi M, Giasson BI, Bonini NM, Lee VM, Trojanowski JQ. Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies. The American Journal of Pathology. 168: 947-61. PMID 16507910 DOI: 10.2353/Ajpath.2006.050770 |
0.312 |
|
| 2006 |
Giasson BI, Covy JP, Bonini NM, Hurtig HI, Farrer MJ, Trojanowski JQ, Van Deerlin VM. Biochemical and pathological characterization of Lrrk2. Annals of Neurology. 59: 315-22. PMID 16437584 DOI: 10.1002/Ana.20791 |
0.362 |
|
| 2005 |
Bonini NM, La Spada AR. Silencing polyglutamine degeneration with RNAi. Neuron. 48: 715-8. PMID 16337909 DOI: 10.1016/j.neuron.2005.11.008 |
0.423 |
|
| 2005 |
Bilen J, Bonini NM. Drosophila as a model for human neurodegenerative disease. Annual Review of Genetics. 39: 153-71. PMID 16285856 DOI: 10.1146/Annurev.Genet.39.110304.095804 |
0.798 |
|
| 2005 |
Bonini NM, Giasson BI. Snaring the function of alpha-synuclein. Cell. 123: 359-61. PMID 16269324 DOI: 10.1016/J.Cell.2005.10.017 |
0.356 |
|
| 2005 |
Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ, Bonini NM. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Current Biology : Cb. 15: 1572-7. PMID 16139213 DOI: 10.1016/J.Cub.2005.07.064 |
0.779 |
|
| 2005 |
Meulener MC, Graves CL, Sampathu DM, Armstrong-Gold CE, Bonini NM, Giasson BI. DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein. Journal of Neurochemistry. 93: 1524-32. PMID 15935068 DOI: 10.1111/J.1471-4159.2005.03145.X |
0.811 |
|
| 2005 |
Warrick JM, Morabito LM, Bilen J, Gordesky-Gold B, Faust LZ, Paulson HL, Bonini NM. Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism. Molecular Cell. 18: 37-48. PMID 15808507 DOI: 10.1016/J.Molcel.2005.02.030 |
0.806 |
|
| 2005 |
Auluck PK, Meulener MC, Bonini NM. Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila. The Journal of Biological Chemistry. 280: 2873-8. PMID 15556931 DOI: 10.1074/jbc.M412106200 |
0.776 |
|
| 2003 |
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 40: 25-40. PMID 14527431 DOI: 10.1016/S0896-6273(03)00594-4 |
0.336 |
|
| 2003 |
Bonini NM, Fortini ME. Human neurodegenerative disease modeling using Drosophila. Annual Review of Neuroscience. 26: 627-56. PMID 12704223 DOI: 10.1146/annurev.neuro.26.041002.131425 |
0.425 |
|
| 2003 |
Atchison L, Ghias A, Wilkinson F, Bonini N, Atchison ML. Transcription factor YY1 functions as a PcG protein in vivo. The Embo Journal. 22: 1347-58. PMID 12628927 DOI: 10.1093/emboj/cdg124 |
0.364 |
|
| 2003 |
Chan HY, Bonini NM. Drosophila models of polyglutamine diseases. Methods in Molecular Biology (Clifton, N.J.). 217: 241-51. PMID 12491937 DOI: 10.1385/1-59259-330-5:241 |
0.361 |
|
| 2002 |
Bonini NM, Fortini ME. Applications of the Drosophila retina to human disease modeling. Results and Problems in Cell Differentiation. 37: 257-75. PMID 25707079 DOI: 10.1007/978-3-540-45398-7_15 |
0.31 |
|
| 2002 |
Auluck PK, Bonini NM. Pharmacological prevention of Parkinson disease in Drosophila. Nature Medicine. 8: 1185-6. PMID 12411925 DOI: 10.1038/nm1102-1185 |
0.712 |
|
| 2002 |
Chan HYE, Warrick JM, Andriola I, Merry D, Bonini NM. Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells Human Molecular Genetics. 11: 2905-2917. PMID 12393802 DOI: 10.1093/Hmg/11.23.2905 |
0.531 |
|
| 2002 |
Chan HY, Warrick JM, Andriola I, Merry D, Bonini NM. Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Human Molecular Genetics. 11: 2895-904. PMID 12393801 DOI: 10.1093/Hmg/11.23.2895 |
0.638 |
|
| 2002 |
Bonini NM. Chaperoning brain degeneration. Proceedings of the National Academy of Sciences of the United States of America. 99: 16407-11. PMID 12149445 DOI: 10.1073/pnas.152330499 |
0.435 |
|
| 2002 |
Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science (New York, N.Y.). 295: 865-8. PMID 11823645 DOI: 10.1126/Science.1067389 |
0.727 |
|
| 2001 |
Bonini NM. Stores to die for. Developmental Cell. 1: 447-8. PMID 11703935 DOI: 10.1016/S1534-5807(01)00061-2 |
0.327 |
|
| 2001 |
Bonini NM. Drosophila as a genetic approach to human neurodegenerative disease. Parkinsonism & Related Disorders. 7: 171-175. PMID 11331183 DOI: 10.1016/S1353-8020(00)00054-7 |
0.473 |
|
| 2000 |
Chan HY, Bonini NM. Drosophila models of human neurodegenerative disease. Cell Death and Differentiation. 7: 1075-80. PMID 11139281 DOI: 10.1038/sj.cdd.4400757 |
0.457 |
|
| 2000 |
Chan HY, Warrick JM, Gray-Board GL, Paulson HL, Bonini NM. Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila. Human Molecular Genetics. 9: 2811-20. PMID 11092757 DOI: 10.1093/Hmg/9.19.2811 |
0.679 |
|
| 2000 |
Paulson HL, Bonini NM, Roth KA. Polyglutamine disease and neuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 97: 12957-8. PMID 11058149 DOI: 10.1073/pnas.210395797 |
0.435 |
|
| 2000 |
Bui QT, Zimmerman JE, Liu H, Gray-Board GL, Bonini NM. Functional analysis of an eye enhancer of the Drosophila eyes absent gene: differential regulation by eye specification genes. Developmental Biology. 221: 355-64. PMID 10790331 DOI: 10.1006/dbio.2000.9688 |
0.305 |
|
| 2000 |
Fortini ME, Bonini NM. Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer. Trends in Genetics : Tig. 16: 161-7. PMID 10729831 DOI: 10.1016/S0168-9525(99)01939-3 |
0.43 |
|
| 1999 |
Warrick JM, Chan HY, Gray-Board GL, Chai Y, Paulson HL, Bonini NM. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nature Genetics. 23: 425-8. PMID 10581028 DOI: 10.1038/70532 |
0.678 |
|
| 1999 |
Bonini NM, Fortini ME. Surviving Drosophila eye development: integrating cell death with differentiation during formation of a neural structure. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 991-1003. PMID 10580984 DOI: 10.1002/(SICI)1521-1878(199912)22:1<991::AID-BIES3>3.0.CO;2-3 |
0.308 |
|
| 1999 |
Chai Y, Koppenhafer SL, Bonini NM, Paulson HL. Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10338-47. PMID 10575031 DOI: 10.1523/Jneurosci.19-23-10338.1999 |
0.428 |
|
| 1999 |
Bonini NM. A genetic model for human polyglutamine-repeat disease in Drosophila melanogaster. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1057-60. PMID 10434305 DOI: 10.1098/rstb.1999.0458 |
0.453 |
|
| 1998 |
Perez MK, Paulson HL, Pendse SJ, Saionz SJ, Bonini NM, Pittman RN. Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation. The Journal of Cell Biology. 143: 1457-70. PMID 9852144 DOI: 10.1083/jcb.143.6.1457 |
0.425 |
|
| 1998 |
Warrick JM, Paulson HL, Gray-Board GL, Bui QT, Fischbeck KH, Pittman RN, Bonini NM. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell. 93: 939-49. PMID 9635424 DOI: 10.1016/S0092-8674(00)81200-3 |
0.688 |
|
| 1998 |
Leiserson WM, Benzer S, Bonini NM. Dual functions of the Drosophila eyes absent gene in the eye and embryo. Mechanisms of Development. 73: 193-202. PMID 9622628 DOI: 10.1016/S0925-4773(98)00052-5 |
0.732 |
|
| 1998 |
Bonini NM, Leiserson WM, Benzer S. Multiple roles of the eyes absent gene in Drosophila. Developmental Biology. 196: 42-57. PMID 9527880 DOI: 10.1006/dbio.1997.8845 |
0.751 |
|
| 1997 |
Bonini NM, Bui QT, Gray-Board GL, Warrick JM. The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates. Development (Cambridge, England). 124: 4819-26. PMID 9428418 |
0.529 |
|
| 1997 |
Zimmerman JE, Bui QT, SteingrÃmsson E, Nagle DL, Fu W, Genin A, Spinner NB, Copeland NG, Jenkins NA, Bucan M, Bonini NM. Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Research. 7: 128-41. PMID 9049631 DOI: 10.1101/Gr.7.2.128 |
0.323 |
|
| 1995 |
Bonini NM, Choi KW. Early decisions in Drosophila eye morphogenesis. Current Opinion in Genetics & Development. 5: 507-15. PMID 7580144 DOI: 10.1016/0959-437X(95)90056-M |
0.541 |
|
| 1994 |
Leiserson WM, Bonini NM, Benzer S. Transvection at the eyes absent gene of Drosophila. Genetics. 138: 1171-9. PMID 7896099 |
0.719 |
|
| 1993 |
Bonini NM, Leiserson WM, Benzer S. The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell. 72: 379-95. PMID 8431945 DOI: 10.1016/0092-8674(93)90115-7 |
0.731 |
|
| 1991 |
Bonini NM, Evans TC, Miglietta LA, Nelson DL. The regulation of ciliary motility in Paramecium by Ca2+ and cyclic nucleotides. Advances in Second Messenger and Phosphoprotein Research. 23: 227-72. PMID 1997042 |
0.324 |
|
| 1990 |
Bonini NM, Nelson DL. Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium. Journal of Cell Science. 95: 219-30. PMID 2164518 |
0.383 |
|
| 1988 |
Bonini NM, Nelson DL. Differential regulation of Paramecium ciliary motility by cAMP and cGMP. The Journal of Cell Biology. 106: 1615-23. PMID 2836435 DOI: 10.1083/Jcb.106.5.1615 |
0.439 |
|
| 1986 |
Bonini NM, Gustin MC, Nelson DL. Regulation of ciliary motility by membrane potential in Paramecium: a role for cyclic AMP. Cell Motility and the Cytoskeleton. 6: 256-72. PMID 2427226 DOI: 10.1002/Cm.970060303 |
0.414 |
|
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