| Year |
Citation |
Score |
| 2014 |
Ptashne M. The chemistry of regulation of genes and other things. The Journal of Biological Chemistry. 289: 5417-35. PMID 24385432 DOI: 10.1074/jbc.X114.547323 |
0.304 |
|
| 2012 |
Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MS, Ptashne M, Brickman JM. Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency. Cell Reports. 1: 99-109. PMID 22832160 DOI: 10.1016/J.Celrep.2011.12.002 |
0.355 |
|
| 2011 |
Wang X, Bai L, Bryant GO, Ptashne M. Nucleosomes and the accessibility problem. Trends in Genetics : Tig. 27: 487-92. PMID 22019336 DOI: 10.1016/j.tig.2011.09.001 |
0.386 |
|
| 2011 |
Ptashne M. Principles of a switch. Nature Chemical Biology. 7: 484-7. PMID 21769089 DOI: 10.1038/nchembio.611 |
0.309 |
|
| 2010 |
Floer M, Wang X, Prabhu V, Berrozpe G, Narayan S, Spagna D, Alvarez D, Kendall J, Krasnitz A, Stepansky A, Hicks J, Bryant GO, Ptashne M. A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding. Cell. 141: 407-18. PMID 20434983 DOI: 10.1016/J.Cell.2010.03.048 |
0.353 |
|
| 2010 |
Wang X, Muratani M, Tansey WP, Ptashne M. Proteolytic instability and the action of nonclassical transcriptional activators. Current Biology : Cb. 20: 868-71. PMID 20417106 DOI: 10.1016/J.Cub.2010.03.029 |
0.477 |
|
| 2010 |
Beckwith J, Herskowitz I, Ptashne M, Signer E, Thomas R. Political discussions at gordon conference. Science (New York, N.Y.). 171: 752. PMID 17812018 DOI: 10.1126/Science.171.3973.752 |
0.612 |
|
| 2008 |
Bryant GO, Prabhu V, Floer M, Wang X, Spagna D, Schreiber D, Ptashne M. Activator control of nucleosome occupancy in activation and repression of transcription. Plos Biology. 6: 2928-39. PMID 19108605 DOI: 10.1371/journal.pbio.0060317 |
0.422 |
|
| 2008 |
Floer M, Bryant GO, Ptashne M. HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast. Proceedings of the National Academy of Sciences of the United States of America. 105: 2975-80. PMID 18287040 DOI: 10.1073/pnas.0800053105 |
0.387 |
|
| 2005 |
Ptashne M. Regulation of transcription: from lambda to eukaryotes. Trends in Biochemical Sciences. 30: 275-9. PMID 15950866 DOI: 10.1016/j.tibs.2005.04.003 |
0.467 |
|
| 2005 |
Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, ... ... Ptashne M, et al. An open letter to Elias Zerhouni. Science (New York, N.Y.). 307: 1409-10. PMID 15746409 DOI: 10.1126/Science.307.5714.1409C |
0.745 |
|
| 2005 |
Ansari AZ, Ogirala A, Ptashne M. Transcriptional activating regions target attached substrates to a cyclin-dependent kinase. Proceedings of the National Academy of Sciences of the United States of America. 102: 2346-9. PMID 15687503 DOI: 10.1073/Pnas.0409671102 |
0.648 |
|
| 2004 |
Cheng JX, Gandolfi M, Ptashne M. Activation of the Gal1 gene of yeast by pairs of 'non-classical' activators. Current Biology : Cb. 14: 1675-9. PMID 15380071 DOI: 10.1016/j.cub.2004.09.025 |
0.503 |
|
| 2004 |
Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, ... ... Ptashne M, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/J.Molcel.2004.05.011 |
0.742 |
|
| 2003 |
Ptashne M. Regulated recruitment and cooperativity in the design of biological regulatory systems. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 361: 1223-34. PMID 12816608 DOI: 10.1098/rsta.2003.1195 |
0.352 |
|
| 2003 |
Bryant GO, Ptashne M. Independent recruitment in vivo by Gal4 of two complexes required for transcription. Molecular Cell. 11: 1301-9. PMID 12769853 DOI: 10.1016/S1097-2765(03)00144-8 |
0.415 |
|
| 2003 |
Saha S, Ansari AZ, Jarrell KA, Ptashne M, Jarell KA. RNA sequences that work as transcriptional activating regions. Nucleic Acids Research. 31: 1565-70. PMID 12595565 DOI: 10.1093/Nar/Gkg227 |
0.639 |
|
| 2003 |
Johnson A, Ptashne M. Obituary: Ira Herskowitz (1946–2003) Nature. 424: 384. DOI: 10.1038/424384A |
0.423 |
|
| 2002 |
Cheng JX, Floer M, Ononaji P, Bryant G, Ptashne M. Responses of four yeast genes to changes in the transcriptional machinery are determined by their promoters. Current Biology : Cb. 12: 1828-32. PMID 12419182 DOI: 10.1016/S0960-9822(02)01257-5 |
0.423 |
|
| 2002 |
Ansari AZ, Koh SS, Zaman Z, Bongards C, Lehming N, Young RA, Ptashne M. Transcriptional activating regions target a cyclin-dependent kinase. Proceedings of the National Academy of Sciences of the United States of America. 99: 14706-9. PMID 12417740 DOI: 10.1073/Pnas.232573899 |
0.683 |
|
| 2002 |
Arora PS, Ansari AZ, Best TP, Ptashne M, Dervan PB. Design of artificial transcriptional activators with rigid poly-L-proline linkers. Journal of the American Chemical Society. 124: 13067-71. PMID 12405833 DOI: 10.1021/Ja0208355 |
0.703 |
|
| 2002 |
Lu Z, Ansari AZ, Lu X, Ogirala A, Ptashne M. A target essential for the activity of a nonacidic yeast transcriptional activator. Proceedings of the National Academy of Sciences of the United States of America. 99: 8591-6. PMID 12084920 DOI: 10.1073/Pnas.092263499 |
0.676 |
|
| 2002 |
Cheng JX, Nevado J, Lu Z, Ptashne M. The TBP-inhibitory domain of TAF145 limits the effects of nonclassical transcriptional activators. Current Biology : Cb. 12: 934-7. PMID 12062059 DOI: 10.1016/S0960-9822(02)00866-7 |
0.504 |
|
| 2002 |
Zaman Z, Heid C, Ptashne M. Telomere looping permits repression "at a distance" in yeast. Current Biology : Cb. 12: 930-3. PMID 12062058 DOI: 10.1016/S0960-9822(02)00865-5 |
0.527 |
|
| 2001 |
Ptashne M, Gann A. Transcription initiation: imposing specificity by localization. Essays in Biochemistry. 37: 1-15. PMID 11758451 DOI: 10.1042/Bse0370001 |
0.315 |
|
| 2001 |
Ansari AZ, Mapp AK, Nguyen DH, Dervan PB, Ptashne M. Towards a minimal motif for artificial transcriptional activators. Chemistry & Biology. 8: 583-92. PMID 11410377 DOI: 10.1016/S1074-5521(01)00037-0 |
0.702 |
|
| 2001 |
de Bruin D, Zaman Z, Liberatore RA, Ptashne M. Telomere looping permits gene activation by a downstream UAS in yeast. Nature. 409: 109-13. PMID 11343124 DOI: 10.1038/35051119 |
0.43 |
|
| 2001 |
Hidalgo P, Ansari AZ, Schmidt P, Hare B, Simkovich N, Farrell S, Shin EJ, Ptashne M, Wagner G. Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain. Genes & Development. 15: 1007-20. PMID 11316794 DOI: 10.1101/Gad.873901 |
0.688 |
|
| 2001 |
Zaman Z, Ansari AZ, Koh SS, Young R, Ptashne M. Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression. Proceedings of the National Academy of Sciences of the United States of America. 98: 2550-4. PMID 11226276 DOI: 10.1073/Pnas.041611198 |
0.695 |
|
| 2000 |
Mapp AK, Ansari AZ, Ptashne M, Dervan PB. Activation of gene expression by small molecule transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 3930-5. PMID 10760265 DOI: 10.1073/Pnas.97.8.3930 |
0.729 |
|
| 2000 |
Torigoi E, Bennani-Baiti IM, Rosen C, Gonzalez K, Morcillo P, Ptashne M, Dorsett D. Chip interacts with diverse homeodomain proteins and potentiates bicoid activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 97: 2686-91. PMID 10688916 DOI: 10.1073/pnas.050586397 |
0.776 |
|
| 2000 |
Lu X, Ansari AZ, Ptashne M. An artificial transcriptional activating region with unusual properties. Proceedings of the National Academy of Sciences of the United States of America. 97: 1988-92. PMID 10681438 DOI: 10.1073/Pnas.040573197 |
0.683 |
|
| 1999 |
Brickman JM, Adam M, Ptashne M. Interactions between an HMG-1 protein and members of the Rel family. Proceedings of the National Academy of Sciences of the United States of America. 96: 10679-83. PMID 10485885 DOI: 10.1073/pnas.96.19.10679 |
0.498 |
|
| 1999 |
Nevado J, Gaudreau L, Adam M, Ptashne M. Transcriptional activation by artificial recruitment in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 2674-7. PMID 10077569 DOI: 10.1073/pnas.96.6.2674 |
0.464 |
|
| 1999 |
Gaudreau L, Keaveney M, Nevado J, Zaman Z, Bryant GO, Struhl K, Ptashne M. Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences. Proceedings of the National Academy of Sciences of the United States of America. 96: 2668-73. PMID 10077568 DOI: 10.1073/Pnas.96.6.2668 |
0.622 |
|
| 1998 |
Zaman Z, Ansari AZ, Gaudreau L, Nevado J, Ptashne M. Gene transcription by recruitment. Cold Spring Harbor Symposia On Quantitative Biology. 63: 167-71. PMID 10384280 DOI: 10.1101/Sqb.1998.63.167 |
0.623 |
|
| 1998 |
Ansari AZ, Reece RJ, Ptashne M. A transcriptional activating region with two contrasting modes of protein interaction. Proceedings of the National Academy of Sciences of the United States of America. 95: 13543-8. PMID 9811836 DOI: 10.1073/Pnas.95.23.13543 |
0.702 |
|
| 1998 |
Gaudreau L, Adam M, Ptashne M. Activation of transcription in vitro by recruitment of the yeast RNA polymerase II holoenzyme. Molecular Cell. 1: 913-6. PMID 9660974 DOI: 10.1016/S1097-2765(00)80090-8 |
0.456 |
|
| 1998 |
Koh SS, Ansari AZ, Ptashne M, Young RA. An activator target in the RNA polymerase II holoenzyme. Molecular Cell. 1: 895-904. PMID 9660972 DOI: 10.1016/S1097-2765(00)80088-X |
0.735 |
|
| 1998 |
Lehming N, Le Saux A, Schüller J, Ptashne M. Chromatin components as part of a putative transcriptional repressing complex. Proceedings of the National Academy of Sciences of the United States of America. 95: 7322-6. PMID 9636147 DOI: 10.1073/pnas.95.13.7322 |
0.507 |
|
| 1997 |
Walters KJ, Dayie KT, Reece RJ, Ptashne M, Wagner G. Structure and mobility of the PUT3 dimer. Nature Structural Biology. 4: 744-50. PMID 9303003 DOI: 10.1038/nsb0997-744 |
0.348 |
|
| 1997 |
Ptashne M, Gann A. Transcriptional activation by recruitment. Nature. 386: 569-77. PMID 9121580 DOI: 10.1038/386569a0 |
0.427 |
|
| 1997 |
Gaudreau L, Schmid A, Blaschke D, Ptashne M, Hörz W. RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter. Cell. 89: 55-62. PMID 9094714 DOI: 10.1016/S0092-8674(00)80182-8 |
0.431 |
|
| 1997 |
Whipple FW, Ptashne M, Hochschild A. The activation defect of a lambda cI positive control mutant. Journal of Molecular Biology. 265: 261-5. PMID 9018040 DOI: 10.1006/Jmbi.1996.0735 |
0.647 |
|
| 1996 |
Farrell S, Simkovich N, Wu Y, Barberis A, Ptashne M. Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes & Development. 10: 2359-67. PMID 8824594 DOI: 10.1101/Gad.10.18.2359 |
0.476 |
|
| 1996 |
Wu Y, Reece RJ, Ptashne M. Quantitation of putative activator-target affinities predicts transcriptional activating potentials. The Embo Journal. 15: 3951-63. PMID 8670900 DOI: 10.1002/J.1460-2075.1996.Tb00769.X |
0.413 |
|
| 1996 |
Liang SD, Marmorstein R, Harrison SC, Ptashne M. DNA sequence preferences of GAL4 and PPR1: how a subset of Zn2 Cys6 binuclear cluster proteins recognizes DNA. Molecular and Cellular Biology. 16: 3773-80. PMID 8668194 DOI: 10.1128/Mcb.16.7.3773 |
0.601 |
|
| 1995 |
Barberis A, Pearlberg J, Simkovich N, Farrell S, Reinagel P, Bamdad C, Sigal G, Ptashne M. Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell. 81: 359-68. PMID 7736588 DOI: 10.1016/0092-8674(95)90389-5 |
0.731 |
|
| 1995 |
Astromoff A, Ptashne M. A variant of lambda repressor with an altered pattern of cooperative binding to DNA sites. Proceedings of the National Academy of Sciences of the United States of America. 92: 8110-4. PMID 7667253 DOI: 10.1073/pnas.92.18.8110 |
0.349 |
|
| 1995 |
Lehming N, McGuire S, Brickman JM, Ptashne M. Interactions of a Rel protein with its inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 92: 10242-6. PMID 7479760 DOI: 10.1073/Pnas.92.22.10242 |
0.393 |
|
| 1994 |
Lehming N, Thanos D, Brickman JM, Ma J, Maniatis T, Ptashne M. An HMG-like protein that can switch a transcriptional activator to a repressor. Nature. 371: 175-9. PMID 8072548 DOI: 10.1038/371175A0 |
0.633 |
|
| 1993 |
Barberis A, Müller CW, Harrison SC, Ptashne M. Delineation of two functional regions of transcription factor TFIIB. Proceedings of the National Academy of Sciences of the United States of America. 90: 5628-32. PMID 8516311 DOI: 10.1073/Pnas.90.12.5628 |
0.607 |
|
| 1993 |
Saha S, Brickman JM, Lehming N, Ptashne M. New eukaryotic transcriptional repressors. Nature. 363: 648-52. PMID 8510759 DOI: 10.1038/363648a0 |
0.519 |
|
| 1993 |
Reece RJ, Rickles RJ, Ptashne M. Overproduction and single-step purification of GAL4 fusion proteins from Escherichia coli. Gene. 126: 105-7. PMID 8472950 DOI: 10.1016/0378-1119(93)90596-U |
0.497 |
|
| 1993 |
Reece RJ, Ptashne M. Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science (New York, N.Y.). 261: 909-11. PMID 8346441 DOI: 10.1126/Science.8346441 |
0.457 |
|
| 1992 |
Marmorstein R, Carey M, Ptashne M, Harrison SC. DNA recognition by GAL4: structure of a protein-DNA complex. Nature. 356: 408-14. PMID 1557122 DOI: 10.1038/356408A0 |
0.618 |
|
| 1992 |
Gann AAF, Himmelfarb HJ, Ptashne M. 35 GAL11, GAL11P, and the Action of GAL4 Cold Spring Harbor Monograph Archive. 931-946. DOI: 10.1101/087969425.22B.931 |
0.517 |
|
| 1991 |
Ruden DM, Ma J, Li Y, Wood K, Ptashne M. Generating yeast transcriptional activators containing no yeast protein sequences. Nature. 350: 250-2. PMID 2005981 DOI: 10.1038/350250A0 |
0.565 |
|
| 1991 |
Sadowski I, Niedbala D, Wood K, Ptashne M. GAL4 is phosphorylated as a consequence of transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 88: 10510-4. PMID 1961715 DOI: 10.1073/Pnas.88.23.10510 |
0.442 |
|
| 1990 |
Carey M, Leatherwood J, Ptashne M. A potent GAL4 derivative activates transcription at a distance in vitro. Science (New York, N.Y.). 247: 710-2. PMID 2405489 DOI: 10.1126/Science.2405489 |
0.476 |
|
| 1990 |
Lin YS, Carey M, Ptashne M, Green MR. How different eukaryotic transcriptional activators can cooperate promiscuously. Nature. 345: 359-61. PMID 2188137 DOI: 10.1038/345359A0 |
0.466 |
|
| 1990 |
Gill G, Sadowski I, Ptashne M. Mutations that increase the activity of a transcriptional activator in yeast and mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 2127-31. PMID 2179950 DOI: 10.1073/Pnas.87.6.2127 |
0.607 |
|
| 1990 |
Carey M, Lin YS, Green MR, Ptashne M. A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature. 345: 361-4. PMID 2160609 DOI: 10.1038/345361A0 |
0.507 |
|
| 1990 |
Ptashne M, Gann AA. Activators and targets. Nature. 346: 329-31. PMID 2142753 DOI: 10.1038/346329a0 |
0.346 |
|
| 1990 |
Himmelfarb HJ, Pearlberg J, Last DH, Ptashne M. GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators. Cell. 63: 1299-309. PMID 2124519 DOI: 10.1016/0092-8674(90)90425-E |
0.494 |
|
| 1989 |
Bushman FD, Shang C, Ptashne M. A single glutamic acid residue plays a key role in the transcriptional activation function of lambda repressor. Cell. 58: 1163-71. PMID 2570642 DOI: 10.1016/0092-8674(89)90514-X |
0.588 |
|
| 1989 |
Chasman DI, Leatherwood J, Carey M, Ptashne M, Kornberg RD. Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro. Molecular and Cellular Biology. 9: 4746-9. PMID 2557540 DOI: 10.1128/MCB.9.11.4746 |
0.309 |
|
| 1989 |
Ptashne M. How gene activators work. Scientific American. 260: 40-7. PMID 2521264 DOI: 10.1038/Scientificamerican0189-40 |
0.312 |
|
| 1989 |
Carey M, Kakidani H, Leatherwood J, Mostashari F, Ptashne M. An amino-terminal fragment of GAL4 binds DNA as a dimer. Journal of Molecular Biology. 209: 423-32. PMID 2511324 DOI: 10.1016/0022-2836(89)90007-7 |
0.514 |
|
| 1989 |
Driever W, Ma J, Nüsslein-Volhard C, Ptashne M. Rescue of bicoid mutant Drosophila embryos by bicoid fusion proteins containing heterologous activating sequences. Nature. 342: 149-54. PMID 2509940 DOI: 10.1038/342149A0 |
0.488 |
|
| 1988 |
Hollis M, Valenzuela D, Pioli D, Wharton R, Ptashne M. A repressor heterodimer binds to a chimeric operator. Proceedings of the National Academy of Sciences of the United States of America. 85: 5834-8. PMID 3413061 DOI: 10.1073/Pnas.85.16.5834 |
0.404 |
|
| 1988 |
Gill G, Ptashne M. Negative effect of the transcriptional activator GAL4. Nature. 334: 721-4. PMID 3412449 DOI: 10.1038/334721A0 |
0.694 |
|
| 1988 |
Koudelka GB, Harbury P, Harrison SC, Ptashne M. DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor. Proceedings of the National Academy of Sciences of the United States of America. 85: 4633-7. PMID 3387430 DOI: 10.1073/Pnas.85.13.4633 |
0.508 |
|
| 1988 |
Harrison SC, Anderson JE, Koudelka GB, Mondragon A, Subbiah S, Wharton RP, Wolberger C, Ptashne M. Recognition of DNA sequences by the repressor of bacteriophage 434. Biophysical Chemistry. 29: 31-7. PMID 3359001 DOI: 10.1016/0301-4622(88)87022-4 |
0.786 |
|
| 1988 |
Aggarwal AK, Rodgers DW, Drottar M, Ptashne M, Harrison SC. Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (New York, N.Y.). 242: 899-907. PMID 3187531 DOI: 10.1126/Science.3187531 |
0.602 |
|
| 1988 |
Wolberger C, Dong YC, Ptashne M, Harrison SC. Structure of a phage 434 Cro/DNA complex. Nature. 335: 789-95. PMID 3185709 DOI: 10.1038/335789A0 |
0.783 |
|
| 1988 |
Ma J, Ptashne M. Converting a eukaryotic transcriptional inhibitor into an activator. Cell. 55: 443-6. PMID 3180218 DOI: 10.1016/0092-8674(88)90030-X |
0.534 |
|
| 1988 |
Ma J, Przibilla E, Hu J, Bogorad L, Ptashne M. Yeast activators stimulate plant gene expression. Nature. 334: 631-3. PMID 3165494 DOI: 10.1038/334631A0 |
0.568 |
|
| 1988 |
Ruden DM, Ma J, Ptashne M. No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 4262-6. PMID 3132708 DOI: 10.1073/Pnas.85.12.4262 |
0.551 |
|
| 1988 |
Fischer JA, Giniger E, Maniatis T, Ptashne M. GAL4 activates transcription in Drosophila. Nature. 332: 853-6. PMID 3128741 DOI: 10.1038/332853A0 |
0.796 |
|
| 1988 |
Giniger E, Ptashne M. Cooperative DNA binding of the yeast transcriptional activator GAL4. Proceedings of the National Academy of Sciences of the United States of America. 85: 382-6. PMID 3124106 DOI: 10.1073/Pnas.85.2.382 |
0.728 |
|
| 1988 |
Ptashne M. How eukaryotic transcriptional activators work. Nature. 335: 683-9. PMID 3050531 DOI: 10.1038/335683a0 |
0.477 |
|
| 1988 |
Sadowski I, Ma J, Triezenberg S, Ptashne M. GAL4-VP16 is an unusually potent transcriptional activator. Nature. 335: 563-4. PMID 3047590 DOI: 10.1038/335563A0 |
0.571 |
|
| 1988 |
Lin YS, Carey MF, Ptashne M, Green MR. GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell. 54: 659-64. PMID 3044607 DOI: 10.1016/S0092-8674(88)80010-2 |
0.41 |
|
| 1988 |
Hochschild A, Ptashne M. Interaction at a distance between lambda repressors disrupts gene activation. Nature. 336: 353-7. PMID 2973565 DOI: 10.1038/336353A0 |
0.674 |
|
| 1988 |
Bushman FD, Ptashne M. Turning lambda Cro into a transcriptional activator. Cell. 54: 191-7. PMID 2968842 DOI: 10.1016/0092-8674(88)90551-X |
0.607 |
|
| 1988 |
Kakidani H, Ptashne M. GAL4 activates gene expression in mammalian cells. Cell. 52: 161-7. PMID 2830021 DOI: 10.1016/0092-8674(88)90504-1 |
0.449 |
|
| 1988 |
Harrison SC, Ptashne M, Anderson JE, Dong YC, Drottar M, Koudelka GB, Mondragon A, Subbiah S, Wharton RP, Wolberger C. Recognition of DNA sequences by the repressor and Cro proteins of bacteriophage 434 Bulletin De L'Institut Pasteur. 86: 55-64. |
0.728 |
|
| 1987 |
Wharton RP, Ptashne M. A new-specificity mutant of 434 repressor that defines an amino acid-base pair contact. Nature. 326: 888-91. PMID 3553961 DOI: 10.1038/326888a0 |
0.431 |
|
| 1987 |
Koudelka GB, Harrison SC, Ptashne M. Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro. Nature. 326: 886-8. PMID 3553960 DOI: 10.1038/326886A0 |
0.536 |
|
| 1987 |
Anderson JE, Ptashne M, Harrison SC. Structure of the repressor-operator complex of bacteriophage 434. Nature. 326: 846-52. PMID 3553959 DOI: 10.1038/326846A0 |
0.583 |
|
| 1987 |
Giniger E, Ptashne M. Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature. 330: 670-2. PMID 3317067 DOI: 10.1038/330670a0 |
0.742 |
|
| 1987 |
Ma J, Ptashne M. The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell. 50: 137-42. PMID 3297349 DOI: 10.1016/0092-8674(87)90670-2 |
0.458 |
|
| 1987 |
Gill G, Ptashne M. Mutants of GAL4 protein altered in an activation function. Cell. 51: 121-6. PMID 3115592 DOI: 10.1016/0092-8674(87)90016-X |
0.618 |
|
| 1987 |
Ma J, Ptashne M. A new class of yeast transcriptional activators. Cell. 51: 113-9. PMID 3115591 DOI: 10.1016/0092-8674(87)90015-8 |
0.524 |
|
| 1987 |
Ma J, Ptashne M. Deletion analysis of GAL4 defines two transcriptional activating segments. Cell. 48: 847-53. PMID 3028647 DOI: 10.1016/0092-8674(87)90081-X |
0.522 |
|
| 1987 |
Irwin N, Ptashne M. Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function. Proceedings of the National Academy of Sciences of the United States of America. 84: 8315-9. PMID 2825186 |
0.399 |
|
| 1986 |
Hochschild A, Ptashne M. Homologous interactions of λ repressor and λ Cro with the λ operator Cell. 44: 925-933. PMID 3955653 DOI: 10.1016/0092-8674(86)90015-2 |
0.625 |
|
| 1986 |
Hochschild A, Ptashne M. Cooperative binding of λ repressors to sites separated by integral turns of the DNA helix Cell. 44: 681-687. PMID 3948245 DOI: 10.1016/0092-8674(86)90833-0 |
0.673 |
|
| 1986 |
Griffith J, Hochschild A, Ptashne M. DNA loops induced by cooperative binding of lambda repressor. Nature. 322: 750-2. PMID 3748156 DOI: 10.1038/322750A0 |
0.648 |
|
| 1986 |
Bushman FD, Ptashne M. Activation of transcription by the bacteriophage 434 repressor. Proceedings of the National Academy of Sciences of the United States of America. 83: 9353-7. PMID 3467310 DOI: 10.1073/Pnas.83.24.9353 |
0.605 |
|
| 1986 |
Silver PA, Brent R, Ptashne M. DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Molecular and Cellular Biology. 6: 4763-6. PMID 3099172 DOI: 10.1128/Mcb.6.12.4763 |
0.586 |
|
| 1986 |
Sharon J, Gefter ML, Manser T, Ptashne M. Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody. Proceedings of the National Academy of Sciences of the United States of America. 83: 2628-31. PMID 3085101 DOI: 10.1073/Pnas.83.8.2628 |
0.359 |
|
| 1986 |
Keegan L, Gill G, Ptashne M. Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein. Science (New York, N.Y.). 231: 699-704. PMID 3080805 DOI: 10.1126/Science.3080805 |
0.791 |
|
| 1986 |
Ptashne M. Gene regulation by proteins acting nearby and at a distance. Nature. 322: 697-701. PMID 3018583 DOI: 10.1038/322697a0 |
0.448 |
|
| 1986 |
Hochschild A, Douhan J, Ptashne M. How lambda repressor and lambda Cro distinguish between OR1 and OR3. Cell. 47: 807-16. PMID 2946418 DOI: 10.1016/0092-8674(86)90523-4 |
0.649 |
|
| 1986 |
Wharton RP, Ptashne M. An α-helix determines the DNA-binding specificity of a repressor Trends in Biochemical Sciences. 11: 71-73. DOI: 10.1016/0968-0004(86)90268-9 |
0.392 |
|
| 1985 |
Bushman FD, Anderson JE, Harrison SC, Ptashne M. Ethylation interference and X-ray crystallography identify similar interactions between 434 repressor and operator Nature. 316: 651-653. PMID 4033762 DOI: 10.1038/316651A0 |
0.682 |
|
| 1985 |
Wharton RP, Ptashne M. Changing the binding specificity of a repressor by redesigning an alpha-helix. Nature. 316: 601-5. PMID 4033758 DOI: 10.1038/316601a0 |
0.385 |
|
| 1985 |
Anderson JE, Ptashne M, Harrison SC. A phage repressor-operator complex at 7 Å resolution Nature. 316: 596-601. PMID 4033757 DOI: 10.1038/316596A0 |
0.586 |
|
| 1985 |
Brent R, Ptashne M. A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene. Nature. 314: 198. PMID 3974723 DOI: 10.1038/314198A0 |
0.328 |
|
| 1985 |
Brent R, Ptashne M. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor Cell. 43: 729-736. PMID 3907859 DOI: 10.1016/0092-8674(85)90246-6 |
0.538 |
|
| 1985 |
Giniger E, Varnum SM, Ptashne M. Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell. 40: 767-74. PMID 3886158 DOI: 10.1016/0092-8674(85)90336-8 |
0.747 |
|
| 1985 |
Eliason JL, Weiss MA, Ptashne M. NH2-terminal arm of phage λ repressor contributes energy and specificity to repressor binding and determines the effects of operator mutations Proceedings of the National Academy of Sciences of the United States of America. 82: 2339-2343. PMID 3157988 DOI: 10.1073/pnas.82.8.2339 |
0.427 |
|
| 1984 |
Wharton RP, Brown EL, Ptashne M. Substituting an alpha-helix switches the sequence-specific DNA interactions of a repressor. Cell. 38: 361-9. PMID 6540625 DOI: 10.1016/0092-8674(84)90491-4 |
0.451 |
|
| 1984 |
Brent R, Ptashne M. A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene Nature. 312: 612-615. PMID 6390216 DOI: 10.1038/312612A0 |
0.461 |
|
| 1984 |
Kimelman D, Lucher LA, Brackmann KH, Symington JS, Ptashne M, Green M. Synthesis in Escherichia coli of human adenovirus type 12 transforming proteins encoded by early region 1A 13S mRNA and 12S mRNA Proceedings of the National Academy of Sciences of the United States of America. 81: 6300-6304. PMID 6387701 DOI: 10.1073/Pnas.81.20.6300 |
0.321 |
|
| 1984 |
Ptashne M. DNA-binding proteins Nature. 308: 753-754. PMID 6371545 DOI: 10.1038/308753c0 |
0.445 |
|
| 1984 |
Anderson J, Ptashne M, Harrison SC. Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator Proceedings of the National Academy of Sciences of the United States of America. 81: 1307-1311. PMID 6369323 DOI: 10.1073/Pnas.81.5.1307 |
0.603 |
|
| 1984 |
Silver PA, Keegan LP, Ptashne M. Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proceedings of the National Academy of Sciences of the United States of America. 81: 5951-5. PMID 6091123 DOI: 10.1073/Pnas.81.19.5951 |
0.691 |
|
| 1983 |
Amann E, Brosius J, Ptashne M. Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli Gene. 25: 167-178. PMID 6363212 DOI: 10.1016/0378-1119(83)90222-6 |
0.41 |
|
| 1983 |
Lewis M, Jeffrey A, Wang J, Ladner R, Ptashne M, Pabo CO. Structure of the operator-binding domain of bacteriophage lambda repressor: implications for DNA recognition and gene regulation. Cold Spring Harbor Symposia On Quantitative Biology. 47: 435-40. PMID 6305562 DOI: 10.1101/Sqb.1983.047.01.051 |
0.785 |
|
| 1983 |
Hochschild A, Irwin N, Ptashne M. Repressor structure and the mechanism of positive control Cell. 32: 319-325. PMID 6218886 DOI: 10.1016/0092-8674(83)90451-8 |
0.677 |
|
| 1982 |
Zinn K, Mellon P, Ptashne M, Maniatis T. Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4897-901. PMID 6956899 DOI: 10.1073/Pnas.79.16.4897 |
0.621 |
|
| 1982 |
Kenyon CJ, Brent R, Ptashne M, Walker GC. Regulation of damage-inducible genes in Escherichia coli Journal of Molecular Biology. 160: 445-457. PMID 6818350 DOI: 10.1016/0022-2836(82)90307-2 |
0.415 |
|
| 1982 |
Sauer RT, Ross MJ, Ptashne M. Cleavage of the lambda and P22 repressors by recA protein. The Journal of Biological Chemistry. 257: 4458-62. PMID 6461657 |
0.537 |
|
| 1982 |
Ptashne M, Johnson AD, Pabo CO. A genetic switch in a bacterial virus. Scientific American. 247: 128-30, 132, 134-40. PMID 6216590 DOI: 10.1038/Scientificamerican1182-128 |
0.732 |
|
| 1982 |
Guarente L, Nye JS, Hochschild A, Ptashne M. Mutant λ phage repressor with a specific defect in its positive control function Proceedings of the National Academy of Sciences of the United States of America. 79: 2236-2239. PMID 6212933 DOI: 10.1073/Pnas.79.7.2236 |
0.73 |
|
| 1981 |
Brent R, Ptashne M. Mechanism of action of the lexA gene product Proceedings of the National Academy of Sciences of the United States of America. 78: 4204-4208. PMID 7027256 DOI: 10.1073/Pnas.78.7.4204 |
0.46 |
|
| 1981 |
Johnson AD, Poteete AR, Lauer G, Sauer RT, Ackers GK, Ptashne M. lambda Repressor and cro--components of an efficient molecular switch. Nature. 294: 217-23. PMID 6457992 DOI: 10.1038/294217A0 |
0.674 |
|
| 1981 |
Guarente L, Ptashne M. Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 78: 2199-2203. PMID 6264467 DOI: 10.1073/Pnas.78.4.2199 |
0.582 |
|
| 1980 |
Brent R, Ptashne M. The lexA gene product represses its own promoter Proceedings of the National Academy of Sciences of the United States of America. 77: 1932-1936. PMID 6990417 DOI: 10.1073/Pnas.77.4.1932 |
0.377 |
|
| 1980 |
Meyer BJ, Ptashne M. Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription. Journal of Molecular Biology. 139: 195-205. PMID 6447796 DOI: 10.1016/0022-2836(80)90304-6 |
0.528 |
|
| 1980 |
Meyer BJ, Maurer R, Ptashne M. Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro. Journal of Molecular Biology. 139: 163-94. PMID 6447795 DOI: 10.1016/0022-2836(80)90303-4 |
0.489 |
|
| 1980 |
Maurer R, Meyer BJ, Ptashne M. Gene regulation at the right operator (OR) of bacteriophage λ. I. OR3 and autogenous negative control by repressor Journal of Molecular Biology. 139: 147-161. PMID 6447794 DOI: 10.1016/0022-2836(80)90302-2 |
0.557 |
|
| 1980 |
Poteete AR, Ptashne M, Ballivet M, Eisen H. Operator sequences of bacteriophages P22 and 21 Journal of Molecular Biology. 137: 81-91. PMID 6445008 DOI: 10.1016/0022-2836(80)90158-8 |
0.364 |
|
| 1980 |
Ptashne M, Jeffrey A, Johnson AD, Maurer R, Meyer BJ, Pabo CO, Roberts TM, Sauer RT. How the lambda repressor and cro work. Cell. 19: 1-11. PMID 6444544 DOI: 10.1016/0092-8674(80)90383-9 |
0.743 |
|
| 1980 |
Guarente L, Lauer G, Roberts TM, Ptashne M. Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit β-globin Cell. 20: 543-553. PMID 6248249 DOI: 10.1016/0092-8674(80)90640-6 |
0.586 |
|
| 1980 |
Taniguchi T, Guarente L, Roberts TM, Kimelman D, Douhan J, Ptashne M. Expression of the human fibroblast interferon gene in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 77: 5230-5233. PMID 6159642 DOI: 10.1073/Pnas.77.9.5230 |
0.506 |
|
| 1980 |
Guarente L, Roberts TM, Ptashne M. A technique for expressing eukaryotic genes in bacteria. Science (New York, N.Y.). 209: 1428-30. PMID 6158095 DOI: 10.1126/Science.6158095 |
0.554 |
|
| 1980 |
Ptashne M. λ Repressor Function and Structure Cold Spring Harbor Monograph Archive. 7: 325-343. DOI: 10.1101/087969133.7.325 |
0.356 |
|
| 1979 |
Sauer RT, Pabo CO, Meyer BJ, Ptashne M, Backman KC. Regulatory functions of the lambda repressor reside in the amino-terminal domain. Nature. 279: 396-400. PMID 16068162 DOI: 10.1038/279396A0 |
0.812 |
|
| 1979 |
Pabo CO, Sauer RT, Sturtevant JM, Ptashne M. The lambda repressor contains two domains. Proceedings of the National Academy of Sciences of the United States of America. 76: 1608-12. PMID 287002 DOI: 10.1073/Pnas.76.4.1608 |
0.778 |
|
| 1979 |
Johnson AD, Meyer BJ, Ptashne M. Interactions between DNA-bound repressors govern regulation by the lambda phage repressor. Proceedings of the National Academy of Sciences of the United States of America. 76: 5061-5. PMID 159452 DOI: 10.1073/Pnas.76.10.5061 |
0.624 |
|
| 1978 |
Backman K, Ptashne M. Maximizing gene expression on a plasmid using recombination in vitro Cell. 13: 65-71. PMID 340049 DOI: 10.1016/0092-8674(78)90138-1 |
0.412 |
|
| 1978 |
Johnson A, Meyer BJ, Ptashne M. Mechanism of action of the cro protein of bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America. 75: 1783-7. PMID 273909 DOI: 10.1073/Pnas.75.4.1783 |
0.695 |
|
| 1977 |
Humayun Z, Kleid D, Ptashne M. Sites of contact between λ operators and λ repressor Nucleic Acids Research. 4: 1595-1607. PMID 896470 DOI: 10.1093/Nar/4.5.1595 |
0.335 |
|
| 1977 |
Humayun Z, Jeffrey A, Ptashne M. Completed DNA sequences and organization of repressor-binding sites in the operators of phage lambda Journal of Molecular Biology. 112: 265-277. PMID 875019 DOI: 10.1016/S0022-2836(77)80143-5 |
0.408 |
|
| 1976 |
Ptashne M, Gilbert W, Baltimore D, Gefter M, Steitz J, Bishop M, Guthrie C, Boyer H, Sobell H, Abelson J, Alberts B. The "sunday seminar". Science (New York, N.Y.). 191: 245. PMID 17832131 DOI: 10.1126/Science.191.4224.245 |
0.563 |
|
| 1976 |
Maniatis T, Ptashne M. A DNA operator-repressor system. Scientific American. 234: 64-6, 71-6. PMID 1251177 DOI: 10.1038/Scientificamerican0176-64 |
0.56 |
|
| 1976 |
Backman K, Ptashne M, Gilbert W. Construction of plasmids carrying the cI gene of bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America. 73: 4174-8. PMID 1069307 DOI: 10.1073/Pnas.73.11.4174 |
0.572 |
|
| 1976 |
Kleid D, Humayun Z, Jeffrey A, Ptashne M. Novel properties of a restriction endonuclease isolated from Haemophilus parahaemolyticus Proceedings of the National Academy of Sciences of the United States of America. 73: 293-297. PMID 1061131 DOI: 10.1073/Pnas.73.2.293 |
0.335 |
|
| 1976 |
Ptashne M, Backman K, Humayun MZ, Jeffrey A, Maurer R, Meyer B, Sauer RT. Autoregulation and function of a repressor in bacteriophage lambda. Science (New York, N.Y.). 194: 156-61. PMID 959843 DOI: 10.1126/Science.959843 |
0.59 |
|
| 1975 |
Maniatis T, Ptashne M, Backman K, Kield D, Flashman S, Jeffrey A, Maurer R. Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell. 5: 109-13. PMID 1095210 DOI: 10.1016/0092-8674(75)90018-5 |
0.606 |
|
| 1975 |
Meyer BJ, Kleid DG, Ptashne M. Lambda repressor turns off transcription of its own gene. Proceedings of the National Academy of Sciences of the United States of America. 72: 4785-89. PMID 1061069 DOI: 10.1073/Pnas.72.12.4785 |
0.584 |
|
| 1974 |
Maniatis T, Ptashne M, Barrell BG, Donelson J. Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature. 250: 394-7. PMID 4854243 DOI: 10.1038/250394A0 |
0.608 |
|
| 1974 |
Maurer R, Maniatis T, Ptashne M. Promoters are in the operators in phage lambda. Nature. 249: 221-3. PMID 4598033 DOI: 10.1038/249221A0 |
0.593 |
|
| 1974 |
Maniatis T, Ptashne M, Maurer R. Control elements in the DNA of bacteriophage lambda. Cold Spring Harbor Symposia On Quantitative Biology. 38: 857-68. PMID 4545512 DOI: 10.1101/Sqb.1974.038.01.088 |
0.543 |
|
| 1973 |
Maniatis T, Ptashne M. Structure of the lambda operators. Nature. 246: 133-6. PMID 4586104 DOI: 10.1038/246133A0 |
0.592 |
|
| 1973 |
Maniatis T, Ptashne M. Multiple repressor binding at the operators in bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America. 70: 1531-5. PMID 4514322 DOI: 10.1073/Pnas.70.5.1531 |
0.573 |
|
| 1971 |
Steinberg RA, Ptashne M. In vitro Repression of RNA Synthesis by Purified λ Phage Repressor Nature. 230: 76-80. PMID 5279042 DOI: 10.1038/Newbio230076A0 |
0.455 |
|
| 1971 |
Eisen H, Ptashne M. Chapter 12 Regulation of Repressor Synthesis Cold Spring Harbor Monograph Archive. 2: 239-245. DOI: 10.1101/087969102.2.239 |
0.318 |
|
| 1971 |
Ptashne M. Chapter 11 Repressor and Its Action Cold Spring Harbor Monograph Archive. 2: 221-237. DOI: 10.1101/087969102.2.221 |
0.384 |
|
| 1971 |
Ptashne M, Pirrotta V, Hopkins N. [40] Isolation of the λ and 434 phage repressors Methods in Enzymology. 21: 487-490. DOI: 10.1016/S0076-6879(71)21042-9 |
0.67 |
|
| 1970 |
Pirrotta V, Chadwick P, Ptashne M. Active form of two coliphage repressors Nature. 227: 41-44. PMID 5422623 DOI: 10.1038/227041a0 |
0.753 |
|
| 1970 |
Ptashne M, Gilbert W. Genetic repressors. Scientific American. 222: 36-44. PMID 4910866 |
0.379 |
|
| 1970 |
Chadwick P, Pirrotta V, Steinberg R, Hopkins N, Ptashne M. The λ and 434 Phage Repressors Cold Spring Harbor Symposia On Quantitative Biology. 35: 283-294. DOI: 10.1101/Sqb.1970.035.01.038 |
0.313 |
|
| 1969 |
Pirrotta V, Ptashne M. Isolation of the 434 phage repressor Nature. 222: 541-544. PMID 5786498 DOI: 10.1038/222541a0 |
0.691 |
|
| 1967 |
Ptashne M. Specific binding of the lambda phage repressor to lambda DNA. Nature. 214: 232-234. PMID 6034235 DOI: 10.1038/214232A0 |
0.478 |
|
| 1965 |
Ptashne M. The detachment and maturation of conserved lambda prophage DNA Journal of Molecular Biology. 11: 90-96. PMID 14255764 DOI: 10.1016/S0022-2836(65)80174-7 |
0.325 |
|
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