| Year |
Citation |
Score |
| 2020 |
Zhang P, Shibata B, Peinado G, Zawadzki RJ, FitzGerald P, Pugh EN. Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram. Investigative Ophthalmology & Visual Science. 61: 9. PMID 32176260 DOI: 10.1167/Iovs.61.3.9 |
0.305 |
|
| 2019 |
Zhang P, Miller EB, Manna SK, Meleppat RK, Pugh EN, Zawadzki RJ. Temporal speckle-averaging of optical coherence tomography volumes for cellular resolution neuronal and vascular retinal imaging. Neurophotonics. 6: 041105. PMID 31528657 DOI: 10.1117/1.Nph.6.4.041105 |
0.369 |
|
| 2019 |
Miller EB, Zhang P, Ching K, Pugh EN, Burns ME. In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 31350349 DOI: 10.1073/Pnas.1903336116 |
0.33 |
|
| 2019 |
Meleppat RK, Zhang P, Ju MJ, Manna SK, Jian Y, Pugh EN, Zawadzki RJ. Directional optical coherence tomography reveals melanin concentration-dependent scattering properties of retinal pigment epithelium. Journal of Biomedical Optics. 24: 1-10. PMID 31254332 DOI: 10.1117/1.JBO.24.6.066011 |
0.382 |
|
| 2019 |
Pugh EN. The mechanism of photon-like dark noise in rod photoreceptors. The Journal of General Physiology. PMID 31171571 DOI: 10.1085/jgp.201912376 |
0.359 |
|
| 2018 |
Zhang P, Mocci J, Wahl DJ, Meleppat RK, Manna SK, Quintavalla M, Muradore R, Sarunic MV, Bonora S, Pugh EN, Zawadzki RJ. Effect of a contact lens for in vivo mouse retinal imaging: Effective focal length changes and monochromatic aberrations. Experimental Eye Research. PMID 29604280 DOI: 10.1016/J.Exer.2018.03.027 |
0.341 |
|
| 2018 |
Ronning KE, Allina GP, Miller EB, Zawadzki RJ, Pugh EN, Hermann R, Burns ME. Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. Experimental Eye Research. PMID 29518352 DOI: 10.1016/J.Exer.2018.02.024 |
0.416 |
|
| 2018 |
Pugh EN. The discovery of the ability of rod photoreceptors to signal single photons. The Journal of General Physiology. PMID 29467164 DOI: 10.1085/jgp.201711970 |
0.342 |
|
| 2018 |
Zhang P, Wahl DJ, Mocci J, Manna SK, Meleppat RK, Bonora S, Sarunic MV, Pugh EN, Zawadzki RJ. Adaptive optics with combined optical coherence tomography and scanning laser ophthalmoscopy for in vivo mouse retina imaging Proceedings of Spie. 10474: 1047427. DOI: 10.1117/12.2288607 |
0.329 |
|
| 2017 |
Lu CD, Lee B, Schottenhamml J, Maier A, Pugh EN, Fujimoto JG. Photoreceptor Layer Thickness Changes During Dark Adaptation Observed With Ultrahigh-Resolution Optical Coherence Tomography. Investigative Ophthalmology & Visual Science. 58: 4632-4643. PMID 28898357 DOI: 10.1167/Iovs.17-22171 |
0.33 |
|
| 2017 |
Zhang P, Zawadzki RJ, Goswami M, Nguyen PT, Yarov-Yarovoy V, Burns ME, Pugh EN. In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320964 DOI: 10.1073/Pnas.1620572114 |
0.421 |
|
| 2017 |
Peinado Allina G, Fortenbach C, Naarendorp F, Gross OP, Pugh EN, Burns ME. Bright flash response recovery of mammalian rods in vivo is rate limited by RGS9. The Journal of General Physiology. PMID 28302678 DOI: 10.1085/Jgp.201611692 |
0.712 |
|
| 2017 |
Zhang P, Goswami M, Pugh EN, Zawadzki RJ. Light induced increases of photoreceptor layer reflectance in response to rhodopsin bleaching in mice measured in vivo with optical coherence tomography (Conference Presentation) Proceedings of Spie. 10045. DOI: 10.1117/12.2251811 |
0.376 |
|
| 2017 |
Goswami M, Wang X, Zhang P, Xiao W, Lam KS, Pugh EN, Zawadzki RJ. Methods for non-surgical cancer nano-theranostics of ocular tumors in the mouse eye (Conference Presentation) Proceedings of Spie. 10045. DOI: 10.1117/12.2251803 |
0.321 |
|
| 2016 |
Zhang P, Goswami M, Zawadzki RJ, Pugh EN. The Photosensitivity of Rhodopsin Bleaching and Light-Induced Increases of Fundus Reflectance in Mice Measured In Vivo With Scanning Laser Ophthalmoscopy. Investigative Ophthalmology & Visual Science. 57: 3650-3664. PMID 27403994 DOI: 10.1167/iovs.16-19393 |
0.352 |
|
| 2016 |
Burns ME, Levine ES, Miller EB, Zam A, Zhang P, Zawadzki RJ, Pugh EN. New Developments in Murine Imaging for Assessing Photoreceptor Degeneration In Vivo. Advances in Experimental Medicine and Biology. 854: 269-75. PMID 26427421 DOI: 10.1007/978-3-319-17121-0_36 |
0.408 |
|
| 2016 |
Jian Y, Cua M, Bonora S, Pugh EN, Zawadzki RJ, Sarunic MV. Coherence gated wavefront sensorless adaptive optics for two photon excited fluorescence retinal imaging(Conference Presentation) Proceedings of Spie. 9712. DOI: 10.1117/12.2213655 |
0.318 |
|
| 2016 |
Goswami M, Zhang P, Pugh EN, Zawadzki RJ. Visualization of chorioretinal vasculature in mice in vivo using a combined OCT/SLO imaging system Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9693. DOI: 10.1117/12.2213609 |
0.329 |
|
| 2016 |
Zhang P, Goswami M, Pugh EN, Zawadzki RJ. Fluorescent scanning laser ophthalmoscopy for cellular resolution in vivo mouse retinal imaging: benefits and drawbacks of implementing adaptive optics Proceedings of Spie. 9693. DOI: 10.1117/12.2213257 |
0.333 |
|
| 2016 |
Bonora S, Lee S, Jian Y, Cua M, Pugh EN, Zawadzki RJ, Sarunic MV. Multi-actuator adaptive lens for wavefront correction in optical coherence tomography and two-photon excitation fluorescence microscopy(Conference Presentation) Proceedings of Spie. 9717: 971702. DOI: 10.1117/12.2211810 |
0.319 |
|
| 2015 |
Zhang P, Zam A, Jian Y, Wang X, Li Y, Lam KS, Burns ME, Sarunic MV, Pugh EN, Zawadzki RJ. In vivo wide-field multispectral scanning laser ophthalmoscopy-optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia, and Müller glia, and mapping of the mouse retinal and choroidal vasculature. Journal of Biomedical Optics. 20: 126005. PMID 26677070 DOI: 10.1117/1.Jbo.20.12.126005 |
0.352 |
|
| 2015 |
Zhang P, Goswami M, Zam A, Pugh EN, Zawadzki RJ. Effect of scanning beam size on the lateral resolution of mouse retinal imaging with SLO. Optics Letters. 40: 5830-3. PMID 26670523 DOI: 10.1364/OL.40.005830 |
0.325 |
|
| 2015 |
Pugh EN. Photoreceptor disc morphogenesis: The classical evagination model prevails. The Journal of Cell Biology. 211: 491-3. PMID 26527745 DOI: 10.1083/jcb.201510067 |
0.34 |
|
| 2015 |
Bonora S, Jian Y, Zhang P, Zam A, Pugh EN, Zawadzki RJ, Sarunic MV. Wavefront correction and high-resolution in vivo OCT imaging with an objective integrated multi-actuator adaptive lens. Optics Express. 23: 21931-41. PMID 26368169 DOI: 10.1364/Oe.23.021931 |
0.315 |
|
| 2015 |
Zawadzki RJ, Zhang P, Zam A, Miller EB, Goswami M, Wang X, Jonnal RS, Lee SH, Kim DY, Flannery JG, Werner JS, Burns ME, Pugh EN. Adaptive-optics SLO imaging combined with widefield OCT and SLO enables precise 3D localization of fluorescent cells in the mouse retina. Biomedical Optics Express. 6: 2191-210. PMID 26114038 DOI: 10.1364/Boe.6.002191 |
0.375 |
|
| 2015 |
Gross OP, Pugh EN, Burns ME. cGMP in mouse rods: the spatiotemporal dynamics underlying single photon responses. Frontiers in Molecular Neuroscience. 8: 6. PMID 25788876 DOI: 10.3389/Fnmol.2015.00006 |
0.674 |
|
| 2015 |
Zhang T, Enemchukwu NO, Jones A, Wang S, Dennis E, Watt CB, Pugh EN, Fu Y. Genetic deletion of S-opsin prevents rapid cone degeneration in a mouse model of Leber congenital amaurosis. Human Molecular Genetics. 24: 1755-63. PMID 25416279 DOI: 10.1093/Hmg/Ddu588 |
0.381 |
|
| 2015 |
Rizzotto L, Bonora S, Jian Y, Zhang P, Zam A, Pugh EN, Mammano F, Zawadzki RJ, Sarunic MV. Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9335. DOI: 10.1117/12.2180145 |
0.331 |
|
| 2015 |
Zhang P, Zam A, Jian Y, Wang X, Burns ME, Sarunic MV, Pugh EN, Zawadzki RJ. Multispectral scanning laser ophthalmoscopy combined with optical coherence tomography for simultaneous in vivo mouse retinal imaging Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9307. DOI: 10.1117/12.2080468 |
0.391 |
|
| 2015 |
Zam A, Zhang P, Jian Y, Sarunic MV, Bonora S, Pugh EN, Zawadzki RJ. Progress on developing wavefront sensorless adaptive optics optical coherence tomography for in vivo retinal imaging in mice Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9312. DOI: 10.1117/12.2077867 |
0.319 |
|
| 2014 |
Levine ES, Zam A, Zhang P, Pechko A, Wang X, FitzGerald P, Pugh EN, Zawadzki RJ, Burns ME. Rapid light-induced activation of retinal microglia in mice lacking Arrestin-1. Vision Research. 102: 71-9. PMID 25091460 DOI: 10.1016/J.Visres.2014.07.011 |
0.423 |
|
| 2014 |
Kessler C, Tillman M, Burns ME, Pugh EN. Rhodopsin in the rod surface membrane regenerates more rapidly than bulk rhodopsin in the disc membranes in vivo. The Journal of Physiology. 592: 2785-97. PMID 24801306 DOI: 10.1113/Jphysiol.2014.272518 |
0.359 |
|
| 2014 |
Zam A, Zhang P, Levine E, Pugh EN, Burns M, Zawadzki RJ. Evaluation of OCT for quantitative in-vivo measurements of changes in neural tissue scattering in longitudinal studies of retinal degeneration in mice Proceedings of Spie. 8934: 893422. DOI: 10.1117/12.2042010 |
0.383 |
|
| 2014 |
Zhang P, Zam A, Pugh EN, Zawadzki RJ. Evaluation of state-of-the-art imaging systems for in vivo monitoring of retinal structure in mice: Current capabilities and limitations Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8930. DOI: 10.1117/12.2040964 |
0.348 |
|
| 2013 |
Haeri M, Calvert PD, Solessio E, Pugh EN, Knox BE. Regulation of rhodopsin-eGFP distribution in transgenic xenopus rod outer segments by light. Plos One. 8: e80059. PMID 24260336 DOI: 10.1371/Journal.Pone.0080059 |
0.37 |
|
| 2013 |
Nikonov SS, Lyubarsky A, Fina ME, Nikonova ES, Sengupta A, Chinniah C, Ding XQ, Smith RG, Pugh EN, Vardi N, Dhingra A. Cones respond to light in the absence of transducin β subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5182-94. PMID 23516284 DOI: 10.1523/Jneurosci.5204-12.2013 |
0.617 |
|
| 2013 |
Bonora S, Jian Y, Pugh EN, Sarunic MV, Zawadzki RJ. AO-OCT for in vivo mouse retinal imaging: Application of adaptive lens in wavefornt sensorless aberration correction Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8934. DOI: 10.1117/12.2042018 |
0.352 |
|
| 2012 |
Gross OP, Pugh EN, Burns ME. Calcium feedback to cGMP synthesis strongly attenuates single-photon responses driven by long rhodopsin lifetimes. Neuron. 76: 370-82. PMID 23083739 DOI: 10.1016/J.Neuron.2013.05.032 |
0.68 |
|
| 2012 |
Gross OP, Pugh EN, Burns ME. Spatiotemporal cGMP dynamics in living mouse rods. Biophysical Journal. 102: 1775-84. PMID 22768933 DOI: 10.1016/J.Bpj.2012.03.035 |
0.685 |
|
| 2012 |
Insinna C, Daniele LL, Davis JA, Larsen DD, Kuemmel C, Wang J, Nikonov SS, Knox BE, Pugh EN. An S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8094-104. PMID 22674284 DOI: 10.1523/Jneurosci.0131-12.2012 |
0.359 |
|
| 2011 |
Daniele LL, Insinna C, Chance R, Wang J, Nikonov SS, Pugh EN. A mouse M-opsin monochromat: retinal cone photoreceptors have increased M-opsin expression when S-opsin is knocked out. Vision Research. 51: 447-58. PMID 21219924 DOI: 10.1016/J.Visres.2010.12.017 |
0.366 |
|
| 2010 |
Naarendorp F, Esdaille TM, Banden SM, Andrews-Labenski J, Gross OP, Pugh EN. Dark light, rod saturation, and the absolute and incremental sensitivity of mouse cone vision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12495-507. PMID 20844144 DOI: 10.1523/Jneurosci.2186-10.2010 |
0.712 |
|
| 2010 |
Burns ME, Pugh EN. Lessons from photoreceptors: turning off g-protein signaling in living cells. Physiology (Bethesda, Md.). 25: 72-84. PMID 20430952 DOI: 10.1152/physiol.00001.2010 |
0.373 |
|
| 2010 |
Ng L, Lyubarsky A, Nikonov SS, Ma M, Srinivas M, Kefas B, St Germain DL, Hernandez A, Pugh EN, Forrest D. Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3347-57. PMID 20203194 DOI: 10.1523/Jneurosci.5267-09.2010 |
0.342 |
|
| 2010 |
Gross OP, Pugh EN, Burns ME. Consequences of Fast, Stochastic Rhodopsin Shutoff for a Model of Phototransduction in Rods Biophysical Journal. 98: 289a. DOI: 10.1016/J.Bpj.2009.12.1575 |
0.664 |
|
| 2009 |
Burns ME, Pugh EN. RGS9 concentration matters in rod phototransduction. Biophysical Journal. 97: 1538-47. PMID 19751658 DOI: 10.1016/j.bpj.2009.06.037 |
0.325 |
|
| 2009 |
Parry DA, Toomes C, Bida L, Danciger M, Towns KV, McKibbin M, Jacobson SG, Logan CV, Ali M, Bond J, Chance R, Swendeman S, Daniele LL, Springell K, Adams M, ... ... Pugh EN, et al. Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice. American Journal of Human Genetics. 84: 683-91. PMID 19409519 DOI: 10.1016/J.Ajhg.2009.04.005 |
0.366 |
|
| 2009 |
Pugh EN, Nikonov S, Davis J, Craft C. Mouse Cone Opsins Require An Arrestin For Normal Inactivation Biophysical Journal. 96: 199a. DOI: 10.1016/J.Bpj.2008.12.1068 |
0.355 |
|
| 2008 |
Nikonov SS, Brown BM, Davis JA, Zuniga FI, Bragin A, Pugh EN, Craft CM. Mouse cones require an arrestin for normal inactivation of phototransduction. Neuron. 59: 462-74. PMID 18701071 DOI: 10.1016/J.Neuron.2008.06.011 |
0.376 |
|
| 2008 |
Daniele LL, Sauer B, Gallagher SM, Pugh EN, Philp NJ. Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice. American Journal of Physiology. Cell Physiology. 295: C451-7. PMID 18524945 DOI: 10.1152/Ajpcell.00124.2008 |
0.376 |
|
| 2008 |
Maguire AM, Simonelli F, Pierce EA, Pugh EN, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, et al. Safety and efficacy of gene transfer for Leber's congenital amaurosis. The New England Journal of Medicine. 358: 2240-8. PMID 18441370 DOI: 10.1056/Nejmoa0802315 |
0.307 |
|
| 2008 |
Feathers KL, Lyubarsky AL, Khan NW, Teofilo K, Swaroop A, Williams DS, Pugh EN, Thompson DA. Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments. Investigative Ophthalmology & Visual Science. 49: 1126-35. PMID 18326740 DOI: 10.1167/Iovs.07-1234 |
0.371 |
|
| 2008 |
Lamb TD, Pugh EN, Collin SP. The Origin of the Vertebrate Eye Evolution: Education and Outreach. 1: 415-426. DOI: 10.1007/s12052-008-0091-2 |
0.591 |
|
| 2007 |
Lamb TD, Collin SP, Pugh EN. Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews. Neuroscience. 8: 960-76. PMID 18026166 DOI: 10.1038/nrn2283 |
0.588 |
|
| 2007 |
Daniele LL, Adams RH, Durante DE, Pugh EN, Philp NJ. Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium. The Journal of Comparative Neurology. 505: 166-76. PMID 17853450 DOI: 10.1002/Cne.21489 |
0.356 |
|
| 2007 |
Liu Q, Tan G, Levenkova N, Li T, Pugh EN, Rux JJ, Speicher DW, Pierce EA. The proteome of the mouse photoreceptor sensory cilium complex. Molecular & Cellular Proteomics : McP. 6: 1299-317. PMID 17494944 DOI: 10.1074/mcp.M700054-MCP200 |
0.31 |
|
| 2007 |
Lin SS, Pugh EN, Engheta N. Polarization imaging in shadow and glare Optics Infobase Conference Papers. DOI: 10.1364/Fio.2007.Jsua13 |
0.473 |
|
| 2006 |
Lin SS, Yemelyanov KM, Pugh EN, Engheta N. Separation and contrast enhancement of overlapping cast shadow components using polarization. Optics Express. 14: 7099-108. PMID 19529081 DOI: 10.1364/Oe.14.007099 |
0.516 |
|
| 2006 |
Lamb TD, Pugh EN. Phototransduction, dark adaptation, and rhodopsin regeneration the proctor lecture. Investigative Ophthalmology & Visual Science. 47: 5137-52. PMID 17122096 DOI: 10.1167/iovs.06-0849 |
0.655 |
|
| 2006 |
Calvert PD, Strissel KJ, Schiesser WE, Pugh EN, Arshavsky VY. Light-driven translocation of signaling proteins in vertebrate photoreceptors. Trends in Cell Biology. 16: 560-8. PMID 16996267 DOI: 10.1016/J.Tcb.2006.09.001 |
0.403 |
|
| 2006 |
Lin SS, Yemelyanov KM, Pugh EN, Engheta N. Polarization-based and specular-reflection-based noncontact latent fingerprint imaging and lifting. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 23: 2137-53. PMID 16912740 DOI: 10.1364/Josaa.23.002137 |
0.477 |
|
| 2006 |
Yemelyanov KM, Lin SS, Pugh EN, Engheta N. Adaptive algorithms for two-channel polarization sensing under various polarization statistics with nonuniform distributions. Applied Optics. 45: 5504-20. PMID 16855649 DOI: 10.1364/Ao.45.005504 |
0.491 |
|
| 2006 |
Nikonov SS, Kholodenko R, Lem J, Pugh EN. Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings. The Journal of General Physiology. 127: 359-74. PMID 16567464 DOI: 10.1085/Jgp.200609490 |
0.383 |
|
| 2006 |
Lin SS, Yemelyanov KM, Pugh EN, Engheta N. Shadow vision enhancement using polarization imaging Optics Infobase Conference Papers. DOI: 10.1364/Fio.2006.Jwd75 |
0.506 |
|
| 2005 |
Pugh EN, Baehr W, Zrenner E. Neuroimaging the retina. Vision Research. 45: 3431. PMID 16289207 DOI: 10.1016/J.Visres.2005.09.040 |
0.353 |
|
| 2005 |
Lyubarsky AL, Savchenko AB, Morocco SB, Daniele LL, Redmond TM, Pugh EN. Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye. Biochemistry. 44: 9880-8. PMID 16026160 DOI: 10.1021/bi0505363 |
0.365 |
|
| 2005 |
Wenzel A, Oberhauser V, Pugh EN, Lamb TD, Grimm C, Samardzija M, Fahl E, Seeliger MW, Remé CE, von Lintig J. The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light. The Journal of Biological Chemistry. 280: 29874-84. PMID 15961402 DOI: 10.1074/jbc.M503603200 |
0.657 |
|
| 2005 |
Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN. Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Investigative Ophthalmology & Visual Science. 46: 2156-67. PMID 15914637 DOI: 10.1167/Iovs.04-1427 |
0.354 |
|
| 2005 |
Nikonov SS, Daniele LL, Zhu X, Craft CM, Swaroop A, Pugh EN. Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. The Journal of General Physiology. 125: 287-304. PMID 15738050 DOI: 10.1085/Jgp.200409208 |
0.398 |
|
| 2005 |
Yemelyanov KM, Lin SS, Pugh EN, Engheta N. Polarization-based segmentation for enhancement of target detection in adaptive polarization-difference imaging Optics Infobase Conference Papers. DOI: 10.1364/Fio.2005.Jwa51 |
0.486 |
|
| 2004 |
Lyubarsky AL, Daniele LL, Pugh EN. From candelas to photoisomerizations in the mouse eye by rhodopsin bleaching in situ and the light-rearing dependence of the major components of the mouse ERG. Vision Research. 44: 3235-51. PMID 15535992 DOI: 10.1016/j.visres.2004.09.019 |
0.355 |
|
| 2004 |
Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death and Differentiation. 11: 1192-7. PMID 15272317 DOI: 10.1038/Sj.Cdd.4401486 |
0.325 |
|
| 2004 |
Peet JA, Bragin A, Calvert PD, Nikonov SS, Mani S, Zhao X, Besharse JC, Pierce EA, Knox BE, Pugh EN. Quantification of the cytoplasmic spaces of living cells with EGFP reveals arrestin-EGFP to be in disequilibrium in dark adapted rod photoreceptors. Journal of Cell Science. 117: 3049-59. PMID 15197244 DOI: 10.1242/Jcs.01167 |
0.317 |
|
| 2004 |
Lamb TD, Pugh EN. Dark adaptation and the retinoid cycle of vision. Progress in Retinal and Eye Research. 23: 307-80. PMID 15177205 DOI: 10.1016/j.preteyeres.2004.03.001 |
0.653 |
|
| 2004 |
Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN, Jacobson SG, Bennett J. In utero gene therapy rescues vision in a murine model of congenital blindness. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 182-8. PMID 14759802 DOI: 10.1016/J.Ymthe.2003.11.013 |
0.354 |
|
| 2004 |
Yemelyanov KM, Lin S, Pugh EN, Engheta N. Bio-Inspired, Adaptive Algorithms for 2- and 3-Channel Polarization Sensing under Various Polarization Statistics with Non-Uniform Distributions Frontiers in Optics. DOI: 10.1364/Fio.2004.Ftug27 |
0.48 |
|
| 2003 |
Liu Q, Lyubarsky A, Skalet JH, Pugh EN, Pierce EA. RP1 is required for the correct stacking of outer segment discs. Investigative Ophthalmology & Visual Science. 44: 4171-83. PMID 14507858 DOI: 10.1167/iovs.03-0410 |
0.308 |
|
| 2003 |
Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN, Maguire AM, Wilson JM, Bennett J. Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. Journal of Virology. 77: 7957-63. PMID 12829835 DOI: 10.1128/Jvi.77.14.7957-7963.2003 |
0.332 |
|
| 2003 |
Yemelyanov KM, Lin S, Luis WQ, Pugh EN, Engheta N. Bio-inspired visualization of polarization information using temporal fusion, flicker, coherently moving dots and texture Frontiers in Optics. DOI: 10.1364/Fio.2003.Wm5 |
0.526 |
|
| 2003 |
Lin S, Yemelyanov KM, Luis WQ, Pugh EN, Engheta N. Biomimetic, adaptive, optimum polarization-opponent imaging of scenes with preferential polarization distributions Frontiers in Optics. DOI: 10.1364/Fio.2003.Mt32 |
0.494 |
|
| 2002 |
Demb JB, Pugh EN. Connexin36 forms synapses essential for night vision. Neuron. 36: 551-3. PMID 12441044 DOI: 10.1016/S0896-6273(02)01062-0 |
0.301 |
|
| 2002 |
Sokolov M, Lyubarsky AL, Strissel KJ, Savchenko AB, Govardovskii VI, Pugh EN, Arshavsky VY. Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation. Neuron. 34: 95-106. PMID 11931744 DOI: 10.1016/S0896-6273(02)00636-0 |
0.414 |
|
| 2002 |
Lyubarsky AL, Lem J, Chen J, Falsini B, Iannaccone A, Pugh EN. Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy. Vision Research. 42: 401-15. PMID 11853756 DOI: 10.1016/S0042-6989(01)00214-0 |
0.345 |
|
| 2002 |
Arshavsky VY, Lamb TD, Pugh EN. G proteins and phototransduction. Annual Review of Physiology. 64: 153-87. PMID 11826267 DOI: 10.1146/Annurev.Physiol.64.082701.102229 |
0.631 |
|
| 2001 |
Rattner A, Smallwood PM, Williams J, Cooke C, Savchenko A, Lyubarsky A, Pugh EN, Nathans J. A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 32: 775-86. PMID 11738025 DOI: 10.1016/S0896-6273(01)00531-1 |
0.372 |
|
| 2001 |
Pugh EN. Rods are rods and cones cones, and (never) the twain shall meet. Neuron. 32: 375-6. PMID 11709146 DOI: 10.1016/S0896-6273(01)00492-5 |
0.35 |
|
| 2000 |
Dhingra A, Lyubarsky A, Jiang M, Pugh EN, Birnbaumer L, Sterling P, Vardi N. The light response of ON bipolar neurons requires G[alpha]o. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9053-8. PMID 11124982 |
0.641 |
|
| 2000 |
Nikonov S, Lamb TD, Pugh EN. The role of steady phosphodiesterase activity in the kinetics and sensitivity of the light-adapted salamander rod photoresponse. The Journal of General Physiology. 116: 795-824. PMID 11099349 DOI: 10.1085/jgp.116.6.795 |
0.634 |
|
| 2000 |
Calvert PD, Krasnoperova NV, Lyubarsky AL, Isayama T, Nicoló M, Kosaras B, Wong G, Gannon KS, Margolskee RF, Sidman RL, Pugh EN, Makino CL, Lem J. Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit. Proceedings of the National Academy of Sciences of the United States of America. 97: 13913-8. PMID 11095744 DOI: 10.1073/Pnas.250478897 |
0.38 |
|
| 2000 |
Leskov IB, Klenchin VA, Handy JW, Whitlock GG, Govardovskii VI, Bownds MD, Lamb TD, Pugh EN, Arshavsky VY. The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron. 27: 525-37. PMID 11055435 DOI: 10.1016/S0896-6273(00)00063-5 |
0.616 |
|
| 2000 |
Lyubarsky AL, Chen C, Simon MI, Pugh EN. Mice lacking G-protein receptor kinase 1 have profoundly slowed recovery of cone-driven retinal responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2209-17. PMID 10704496 DOI: 10.1523/Jneurosci.20-06-02209.2000 |
0.417 |
|
| 2000 |
Dhingra A, Lyubarsky A, Jiang M, Pugh EN, Birnbaumer L, Sterling P, Vardi N. The Light Response of ON Bipolar Neurons Requires Gαo The Journal of Neuroscience. 20: 9053-9058. DOI: 10.1523/Jneurosci.20-24-09053.2000 |
0.687 |
|
| 2000 |
Pugh EN, Lamb TD. Chapter 5 Phototransduction in vertebrate rods and cones: Molecular mechanisms of amplification, recovery and light adaptation Handbook of Biological Physics. 3: 183-255. DOI: 10.1016/S1383-8121(00)80008-1 |
0.602 |
|
| 1999 |
Pugh EN, Nikonov S, Lamb TD. Molecular mechanisms of vertebrate photoreceptor light adaptation. Current Opinion in Neurobiology. 9: 410-8. PMID 10448166 DOI: 10.1016/S0959-4388(99)80062-2 |
0.635 |
|
| 1999 |
Lyubarsky AL, Falsini B, Pennesi ME, Valentini P, Pugh EN. UV- and midwave-sensitive cone-driven retinal responses of the mouse: a possible phenotype for coexpression of cone photopigments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 442-55. PMID 9870972 DOI: 10.1523/Jneurosci.19-01-00442.1999 |
0.384 |
|
| 1998 |
Nikonov S, Engheta N, Pugh EN. Kinetics of recovery of the dark-adapted salamander rod photoresponse. The Journal of General Physiology. 111: 7-37. PMID 9417132 DOI: 10.1085/Jgp.111.1.7 |
0.444 |
|
| 1998 |
Tyo JS, Pugh EN, Engheta N. Colorimetric representations for use with polarization-difference imaging of objects in scattering media Journal of the Optical Society of America a: Optics and Image Science, and Vision. 15: 367-374. DOI: 10.1364/Josaa.15.000367 |
0.49 |
|
| 1997 |
Pugh EN, Duda T, Sitaramayya A, Sharma RK. Photoreceptor guanylate cyclases: a review. Bioscience Reports. 17: 429-73. PMID 9419388 DOI: 10.1023/A:1027365520442 |
0.327 |
|
| 1997 |
Cideciyan AV, Pugh EN, Lamb TD, Huang Y, Jacobson SG. Rod plateaux during dark adaptation in Sorsby's fundus dystrophy and vitamin A deficiency. Investigative Ophthalmology & Visual Science. 38: 1786-94. PMID 9286267 |
0.539 |
|
| 1996 |
Tyo JS, Rowe MP, Pugh EN, Engheta N. Target detection in optically scattering media by polarization-difference imaging. Applied Optics. 35: 1855-70. PMID 21085310 DOI: 10.1364/Ao.35.001855 |
0.646 |
|
| 1996 |
Rowe MP, Corless JM, Engheta N, Pugh EN. Scanning interferometry of sunfish cones. I. Longitudinal variation in single-cone refractive index Journal of the Optical Society of America a: Optics and Image Science, and Vision. 13: 2141-2150. DOI: 10.1364/Josaa.13.002141 |
0.356 |
|
| 1996 |
Jiang H, Lyubarsky A, Vardi N, Pugh EN, Chen J, Xu J, Simon MI, Wu D. Phospholipase β4-knockout mouse exhibits retinal phenotype Investigative Ophthalmology and Visual Science. 37: S809. |
0.498 |
|
| 1995 |
Rowe MP, Pugh EN, Tyo JS, Engheta N. Polarization-difference imaging: a biologically inspired technique for observation through scattering media. Optics Letters. 20: 608-10. PMID 19859271 DOI: 10.1364/Ol.20.000608 |
0.656 |
|
| 1994 |
Breton ME, Schueller AW, Lamb TD, Pugh EN. Analysis of ERG a-wave amplification and kinetics in terms of the G-protein cascade of phototransduction. Investigative Ophthalmology & Visual Science. 35: 295-309. PMID 8300357 |
0.538 |
|
| 1994 |
Rowe MP, Engheta N, Easter SS, Pugh EN. Graded-index model of a fish double cone exhibits differential polarization sensitivity. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 11: 55-70. PMID 8106915 DOI: 10.1364/Josaa.11.000055 |
0.541 |
|
| 1994 |
Dumke CL, Arshavsky VY, Calvert PD, Bownds MD, Pugh EN. Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase. The Journal of General Physiology. 103: 1071-98. PMID 7931138 DOI: 10.1085/Jgp.103.6.1071 |
0.353 |
|
| 1993 |
Pugh EN, Lamb TD. Amplification and kinetics of the activation steps in phototransduction. Biochimica Et Biophysica Acta. 1141: 111-49. PMID 8382952 DOI: 10.1016/0005-2728(93)90038-H |
0.594 |
|
| 1993 |
Olson A, Pugh EN. Diffusion coefficient of cyclic GMP in salamander rod outer segments estimated with two fluorescent probes. Biophysical Journal. 65: 1335-52. PMID 8241412 DOI: 10.1016/S0006-3495(93)81177-9 |
0.309 |
|
| 1992 |
Lamb TD, Pugh EN. G-protein cascades: gain and kinetics. Trends in Neurosciences. 15: 291-8. PMID 1384198 DOI: 10.1016/0166-2236(92)90079-N |
0.589 |
|
| 1992 |
Lamb TD, Pugh EN. A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors. The Journal of Physiology. 449: 719-58. PMID 1326052 DOI: 10.1113/Jphysiol.1992.Sp019111 |
0.614 |
|
| 1992 |
Calkins DJ, Thornton JE, Pugh EN. Monochromatism determined at a long-wavelength/middle-wavelength cone-antagonistic locus. Vision Research. 32: 2349-67. PMID 1288011 DOI: 10.1016/0042-6989(92)90098-4 |
0.309 |
|
| 1991 |
Cameron DA, Pugh EN. Double cones as a basis for a new type of polarization vision in vertebrates. Nature. 353: 161-4. PMID 1891046 DOI: 10.1038/353161a0 |
0.36 |
|
| 1990 |
Cameron DA, Pugh EN. The magnitude, time course and spatial distribution of current induced in salamander rods by cyclic guanine nucleotides. The Journal of Physiology. 430: 419-39. PMID 1964967 DOI: 10.1113/Jphysiol.1990.Sp018299 |
0.325 |
|
| 1990 |
Pugh EN, Lamb TD. Cyclic GMP and calcium: the internal messengers of excitation and adaptation in vertebrate photoreceptors. Vision Research. 30: 1923-48. PMID 1962979 DOI: 10.1016/0042-6989(90)90013-B |
0.629 |
|
| 1988 |
Barkdoll AE, Pugh EN, Sitaramayya A. Kinetics of the hydrolysis of 8-bromo-cyclic GMP by the light-activated phosphodiesterase of toad rods. Journal of Neurochemistry. 50: 839-46. PMID 2828548 DOI: 10.1111/J.1471-4159.1988.Tb02989.X |
0.331 |
|
| 1987 |
Pugh EN. The nature and identity of the internal excitational transmitter of vertebrate phototransduction. Annual Review of Physiology. 49: 715-41. PMID 3032080 DOI: 10.1146/annurev.ph.49.030187.003435 |
0.364 |
|
| 1985 |
Friedman LJ, Thornton JE, Pugh EN. Cone antagonism along visual pathways of red/green dichromats. Vision Research. 25: 1647-54. PMID 3879568 DOI: 10.1016/0042-6989(85)90136-1 |
0.326 |
|
| 1985 |
Cobbs WH, Barkdoll AE, Pugh EN. Cyclic GMP increases photocurrent and light sensitivity of retinal cones. Nature. 317: 64-6. PMID 2993915 DOI: 10.1038/317064a0 |
0.431 |
|
| 1985 |
Cobbs WH, Pugh EN. Cyclic GMP can increase rod outer-segment light-sensitive current 10-fold without delay of excitation. Nature. 313: 585-7. PMID 2982108 DOI: 10.1038/313585a0 |
0.392 |
|
| 1984 |
Liebman PA, Mueller P, Pugh EN. Protons suppress the dark current of frog retinal rods. The Journal of Physiology. 347: 85-110. PMID 6608584 DOI: 10.1113/Jphysiol.1984.Sp015055 |
0.356 |
|
| 1984 |
Friedman LJ, Yim MH, Pugh EN. Temporal integration of the pi 1/pi 3 pathway in normal and dichromatic vision. Vision Research. 24: 743-50. PMID 6331680 DOI: 10.1016/0042-6989(84)90215-3 |
0.302 |
|
| 1983 |
Thornton JE, Pugh EN. Red/Green color opponency at detection threshold. Science (New York, N.Y.). 219: 191-3. PMID 6849131 DOI: 10.1126/Science.6849131 |
0.344 |
|
| 1983 |
Mueller P, Pugh EN. Protons block the dark current of isolated retinal rods. Proceedings of the National Academy of Sciences of the United States of America. 80: 1892-6. PMID 6300877 DOI: 10.1073/Pnas.80.7.1892 |
0.316 |
|
| 1981 |
Liebman PA, Pugh EN. Chapter 9 Control of Rod Disk Membrane Phosphodiesterase and a Model for Visual Transduction Current Topics in Membranes and Transport. 15: 157-170. DOI: 10.1016/S0070-2161(08)60500-6 |
0.323 |
|
| 1980 |
Pugh EN, Larimer J. Test of the identity of the site of blue/yellow hue cancellation and the site of chromatic antagonism in the pi 1 pathway. Vision Research. 20: 779-88. PMID 7456339 DOI: 10.1016/0042-6989(80)90009-7 |
0.301 |
|
| 1980 |
Wandell BA, Pugh EN. Detection of long-duration, long-wavelength incremental flashes by a chromatically coded pathway. Vision Research. 20: 625-36. PMID 7434597 DOI: 10.1016/0042-6989(80)90119-4 |
0.524 |
|
| 1980 |
Wandell BA, Pugh EN. A field-additive pathway detects brief-duration, long-wavelength incremental flashes. Vision Research. 20: 613-24. PMID 7434596 DOI: 10.1016/0042-6989(80)90118-2 |
0.531 |
|
| 1980 |
Liebman PA, Pugh EN. ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes. Nature. 287: 734-6. PMID 6107856 DOI: 10.1038/287734A0 |
0.344 |
|
| 1977 |
Augenstein EJ, Pugh EN. The dynamics of the pi 1 colour mechanism: further evidence for two sites of adaptation. The Journal of Physiology. 272: 247-81. PMID 592192 DOI: 10.1113/jphysiol.1977.sp012043 |
0.3 |
|
| 1977 |
Alpern M, Pugh EN. Variation in the action spectrum of erythrolabe among deuteranopes. The Journal of Physiology. 266: 613-46. PMID 301186 DOI: 10.1113/jphysiol.1977.sp011785 |
0.587 |
|
| 1976 |
Alpern M, Bastian B, Pugh EN, Gras W. Altered ocular pigments, photostable and labile: two causes of deuteranomalous trichromacy. Modern Problems in Ophthalmology. 17: 273-91. PMID 1085880 |
0.506 |
|
| 1975 |
Pugh EN. Rushton's paradox: rod dark adaptation after flash photolysis. The Journal of Physiology. 248: 413-31. PMID 1151791 DOI: 10.1113/jphysiol.1975.sp010982 |
0.327 |
|
| 1975 |
Pugh EN. Rhodopsin flash photolysis in man. The Journal of Physiology. 248: 393-412. PMID 1151790 DOI: 10.1113/jphysiol.1975.sp010981 |
0.315 |
|
| 1974 |
Alpern M, Pugh EN. The density and photosensitivity of human rhodopsin in the living retina. The Journal of Physiology. 237: 341-70. PMID 4825455 DOI: 10.1113/jphysiol.1974.sp010485 |
0.618 |
|
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