Aditi Das, Ph.D. - Publications

Affiliations: 
2001-2006 Chemistry Princeton University, Princeton, NJ 
 2006-2022 Biochemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2022- Chemistry and Biochemistry Georgia Institute of Technology, Atlanta, GA 
Area:
Lipid Biochemistry
Website:
https://sites.google.com/site/aditidaspro

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huff HC, Kim JS, Ojha A, Sinha S, Das A. Real time changes in the expression of eicosanoid synthesizing enzymes during inflammation. Prostaglandins & Other Lipid Mediators. 106839. PMID 38679226 DOI: 10.1016/j.prostaglandins.2024.106839  0.8
2024 Roy P, Maturano J, Hasdemir H, Lopez A, Xu F, Hellman J, Tajkhorshid E, Sarlah D, Das A. Elucidating the Mechanism of Metabolism of Cannabichromene by Human Cytochrome P450s. Journal of Natural Products. PMID 38477310 DOI: 10.1021/acs.jnatprod.3c00336  0.705
2023 Louie AY, Kim JS, Drnevich J, Dibaeinia P, Koito H, Sinha S, McKim DB, Soto-Diaz K, Nowak RA, Das A, Steelman AJ. Influenza A virus infection disrupts oligodendrocyte homeostasis and alters the myelin lipidome in the adult mouse. Journal of Neuroinflammation. 20: 190. PMID 37596606 DOI: 10.1186/s12974-023-02862-2  0.637
2023 Kim JS, Soto-Diaz K, Bingham TW, Steelman AJ, Das A. Role of Omega-3 Endocannabinoids in the Modulation of T-cell Activity in a Multiple Sclerosis Experimental Autoimmune Encephalomyelitis (EAE) Model. The Journal of Biological Chemistry. 102886. PMID 36626985 DOI: 10.1016/j.jbc.2023.102886  0.588
2022 Roy P, Dennis DG, Eschbach MD, Anand SD, Xu F, Maturano J, Hellman J, Sarlah D, Das A. Metabolites of Cannabigerol Generated by Human Cytochrome P450s Are Bioactive. Biochemistry. PMID 36223199 DOI: 10.1021/acs.biochem.2c00383  0.753
2022 Dennis DG, Anand SD, Lopez AJ, Petrovčič J, Das A, Sarlah D. Synthesis of the Cannabimovone and Cannabifuran Class of Minor Phytocannabinoids and Their Anti-inflammatory Activity. The Journal of Organic Chemistry. PMID 35476908 DOI: 10.1021/acs.joc.2c00336  0.586
2022 Xie Z, Feng J, Cai T, McCarthy R, Eschbach Ii MD, Wang Y, Zhao Y, Yi Z, Zang K, Yuan Y, Hu X, Li F, Liu Q, Das A, England SK, et al. Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain. Jci Insight. PMID 35420999 DOI: 10.1172/jci.insight.149107  0.516
2022 Dutta S, Selvam B, Das A, Shukla D. Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors. The Journal of Biological Chemistry. 298: 101764. PMID 35227761 DOI: 10.1016/j.jbc.2022.101764  0.66
2022 Kim JS, Arango AS, Shah S, Arnold WR, Tajkhorshid E, Das A. Anthracycline derivatives inhibit cardiac CYP2J2. Journal of Inorganic Biochemistry. 229: 111722. PMID 35078036 DOI: 10.1016/j.jinorgbio.2022.111722  0.504
2021 Huff HC, Vasan A, Roy P, Kaul A, Tajkhorshid E, Das A. Differential Interactions of Selected Phytocannabinoids with Human CYP2D6 Polymorphisms. Biochemistry. PMID 34491040 DOI: 10.1021/acs.biochem.1c00158  0.794
2021 Arnold WR, Carnevale LN, Xie Z, Baylon JL, Tajkhorshid E, Hu H, Das A. Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel. Nature Communications. 12: 926. PMID 33568652 DOI: 10.1038/s41467-021-20946-6  0.664
2020 Yeung J, Adili R, Yamaguchi A, Freedman CJ, Chen A, Shami R, Das A, Holman TR, Holinstat M. Omega-6 DPA and its 12-lipoxygenase-oxidized lipids regulate platelet reactivity in a nongenomic PPARα-dependent manner. Blood Advances. 4: 4522-4537. PMID 32946570 DOI: 10.1182/Bloodadvances.2020002493  0.615
2020 Das A, Weigle AT, Arnold WR, Kim JS, Carnevale LN, Huff HC. CYP2J2 Molecular Recognition: A New Axis for Therapeutic Design. Pharmacology & Therapeutics. 107601. PMID 32534953 DOI: 10.1016/J.Pharmthera.2020.107601  0.783
2020 Torrens A, Vozella V, Huff H, McNeil B, Ahmed F, Ghidini A, Mahler SV, Huestis MA, Das A, Piomelli D. Comparative Pharmacokinetics of Δ-Tetrahydrocannabinol in Adolescent and Adult Male Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 32345621 DOI: 10.1124/Jpet.120.265892  0.761
2020 Arango AS, Yadav A, Reinhardt CJ, Huff HC, Dong L, Das A, Malkowski MG, Chan J, Tajkhorshid E. Two Step Mechanism of an Activity-Based Fluorescent Probe for Cyclooxygenase-2 Biophysical Journal. 118: 47a. DOI: 10.1016/J.Bpj.2019.11.436  0.754
2019 Yadav AK, Reinhardt CJ, Arango AS, Huff HC, Dong L, Malkowski MG, Das A, Tajkhorshid E, Chan J. An Activity-based Sensing Approach for the Detection of Cyclooxygenase-2 in Live Cells. Angewandte Chemie (International Ed. in English). PMID 31854058 DOI: 10.1002/Anie.201914845  0.777
2019 Carnevale LN, Das A. Novel Anti-inflammatory and Vasodilatory ω-3 Endocannabinoid Epoxide Regioisomers. Advances in Experimental Medicine and Biology. 1161: 219-232. PMID 31562632 DOI: 10.1007/978-3-030-21735-8_17  0.374
2019 R Arnold W, Zelasko S, D Meling D, Sam K, Das A. Polymorphisms of CYP2C8 Alter First-Electron Transfer Kinetics and Increase Catalytic Uncoupling. International Journal of Molecular Sciences. 20. PMID 31540428 DOI: 10.3390/Ijms20184626  0.337
2019 Caputo MP, Radlowski EC, Lawson M, Antonson A, Watson JE, Matt SM, Leyshon BJ, Das A, Johnson RW. Herring Roe Oil Supplementation Alters Microglial Cell Gene Expression and Reduces Peripheral Inflammation After Immune Activation in a Neonatal Piglet Model. Brain, Behavior, and Immunity. PMID 31271868 DOI: 10.1016/J.Bbi.2019.06.046  0.682
2019 Das A, Watson J, Carnevale L, Arnold W. Omega-3 Endocannabinoid-Epoxides Are Novel Anti-inflammatory and Anti-Pain Lipid Metabolites (FS15-01-19). Current Developments in Nutrition. 3. PMID 31223777 DOI: 10.1093/cdn/nzz031.FS15-01-19  0.613
2019 Watson JE, Kim JS, Das A. Emerging Class of Omega-3 Fatty Acid Endocannabinoids & Their Derivatives. Prostaglandins & Other Lipid Mediators. 106337. PMID 31085370 DOI: 10.1016/J.Prostaglandins.2019.106337  0.635
2019 Huff HC, Maroutsos D, Das A. Lipid Composition and Macromolecular Crowding Effects on CYP2J2-Mediated Drug Metabolism in Nanodiscs. Protein Science : a Publication of the Protein Society. PMID 30861250 DOI: 10.1002/Pro.3603  0.817
2019 Maroutsos D, Huff H, Das A. Bacterial Expression of Membrane-Associated Cytochrome P450s and Their Activity Assay in Nanodiscs. Methods in Molecular Biology (Clifton, N.J.). 1927: 47-72. PMID 30788785 DOI: 10.1007/978-1-4939-9142-6_5  0.798
2018 Roy J, Dibaeinia P, Fan TM, Sinha S, Das A. Global Analysis of Osteosarcoma Lipidomes Reveal Altered Lipid Profiles in Metastatic vs. Non-Metastatic Cells. Journal of Lipid Research. PMID 30504231 DOI: 10.1194/Jlr.M088559  0.784
2018 Nelson NG, Law WX, Weingarten MJ, Carnevale LN, Das A, Liang NC. Combined ∆-tetrahydrocannabinol and moderate alcohol administration: effects on ingestive behaviors in adolescent male rats. Psychopharmacology. PMID 30415276 DOI: 10.1007/S00213-018-5093-3  0.563
2018 Carnevale L, Arango A, Arnold WR, Tajkhorshid E, Das A. Endocannabinoid Virodhamine is an Endogenous Inhibitor of Human Cardiovascular CYP2J2 Epoxygenase. Biochemistry. PMID 30285425 DOI: 10.1021/Acs.Biochem.8B00691  0.522
2018 Roy J, Watson JE, Hong I, Fan TM, Das A. Anti-Tumorigenic Properties of Omega-3 Endocannabinoid Epoxides. Journal of Medicinal Chemistry. PMID 29856219 DOI: 10.1021/Acs.Jmedchem.8B00243  0.771
2018 Arnold WR, Weigle AT, Das A. Cross-talk of cannabinoid and endocannabinoid metabolism is mediated via human cardiac CYP2J2. Journal of Inorganic Biochemistry. 184: 88-99. PMID 29689453 DOI: 10.1016/J.Jinorgbio.2018.03.016  0.792
2017 Arnold WR, Baylon JL, Tajkhorshid E, Das A. Arachidonic Acid Metabolism by Human Cardiovascular CYP2J2 Is Modulated by Doxorubicin. Biochemistry. 56: 6700-6712. PMID 29200270 DOI: 10.1021/Acs.Biochem.7B01025  0.579
2017 Roy J, Wycislo KL, Pondenis H, Fan TM, Das A. Comparative proteomic investigation of metastatic and non-metastatic osteosarcoma cells of human and canine origin. Plos One. 12: e0183930. PMID 28910304 DOI: 10.1371/Journal.Pone.0183930  0.783
2017 McDougle DR, Watson JE, Abdeen AA, Adili R, Caputo MP, Krapf JE, Johnson RW, Kilian KA, Holinstat M, Das A. Anti-inflammatory ω-3 endocannabinoid epoxides. Proceedings of the National Academy of Sciences of the United States of America. PMID 28687674 DOI: 10.1073/Pnas.1610325114  0.782
2017 Rouck J, Krapf J, Roy J, Huff H, Das A. Recent Advances in Nanodisc Technology for Membrane Protein Studies (2012-2017). Febs Letters. PMID 28581067 DOI: 10.1002/1873-3468.12706  0.765
2017 Rouck JE, Biggs BW, Kambalyal A, Arnold WR, De Mey M, Ajikumar PK, Das A. Heterologous expression and characterization of plant taxadiene-5α-Hydroxylase (CYP725A4) in Escherichia coli. Protein Expression and Purification. PMID 28109855 DOI: 10.1016/J.Pep.2017.01.008  0.384
2016 Arnold WR, Baylon JL, Tajkhorshid E, Das A. Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. Biochemistry. 55: 6969-6980. PMID 27992998 DOI: 10.1021/Acs.Biochem.6B01037  0.562
2016 Roy J, Adili R, Kulmacz RJ, Holinstat M, Das A. Development of Poly Unsaturated Fatty Acid Derivatives of Aspirin for Inhibition of Platelet Function. The Journal of Pharmacology and Experimental Therapeutics. PMID 27488919 DOI: 10.1124/Jpet.116.234781  0.777
2016 Biggs BW, Rouck JE, Kambalyal A, Arnold W, Lim CG, de Mey M, O'Neil-Johnson M, Starks CM, Das A, Ajikumar PK. Orthogonal assays clarify the oxidative biochemistry of Taxol P450 CYP725A4. Acs Chemical Biology. PMID 26930136 DOI: 10.1021/Acschembio.5B00968  0.65
2016 Plucinski L, Ranjan Gartia M, Arnold WR, Ameen A, Chang TW, Hsiao A, Logan Liu G, Das A. Substrate binding to cytochrome P450-2J2 in Nanodiscs detected by nanoplasmonic Lycurgus cup arrays. Biosensors & Bioelectronics. 75: 337-46. PMID 26334592 DOI: 10.1016/J.Bios.2015.07.041  0.344
2015 Lim SJ, McDougle DR, Zahid MU, Ma L, Das A, Smith AM. Lipoprotein Nanoplatelets: Brightly Fluorescent, Zwitterionic Probes with Rapid Cellular Entry. Journal of the American Chemical Society. PMID 26687504 DOI: 10.1021/Jacs.5B11225  0.76
2015 Saha A, Das A, Chakraborty A, Roy M, Ram MK, Sarkar A, Nayak C. An experimental analysis of the strength of the taper joint. Technology and Health Care : Official Journal of the European Society For Engineering and Medicine. PMID 26578284 DOI: 10.3233/THC-151115  0.368
2015 Roy J, Pondenis H, Fan TM, Das A. Direct Capture of Functional Proteins from Mammalian Plasma Membranes into Nanodiscs. Biochemistry. PMID 26415091 DOI: 10.1021/Acs.Biochem.5B00954  0.786
2015 McDougle DR, Baylon JL, Meling DD, Kambalyal A, Grinkova YV, Hammernik J, Tajkhorshid E, Das A. Incorporation of charged residues in the CYP2J2 F-G loop disrupts CYP2J2-lipid bilayer interactions. Biochimica Et Biophysica Acta. 1848: 2460-70. PMID 26232558 DOI: 10.1016/J.Bbamem.2015.07.015  0.778
2015 Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL. Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers. Plos One. 10: e0125263. PMID 25928376 DOI: 10.1371/Journal.Pone.0125263  0.538
2015 Meling DD, Zelasko S, Kambalyal A, Roy J, Das A. Functional role of the conserved i-helix residue I346 in CYP5A1-Nanodiscs. Biophysical Chemistry. 200: 34-40. PMID 25900452 DOI: 10.1016/J.Bpc.2015.03.002  0.787
2015 Zelasko S, Arnold WR, Das A. Endocannabinoid metabolism by cytochrome P450 monooxygenases. Prostaglandins & Other Lipid Mediators. 116: 112-23. PMID 25461979 DOI: 10.1016/J.Prostaglandins.2014.11.002  0.388
2015 Dey S, Sarkar S, Das A, Karmakar A, Adhikari S. Effect of twist and rotation on vibration of functionally graded conical shells International Journal of Mechanics and Materials in Design. 11: 425-437. DOI: 10.1007/s10999-014-9266-x  0.311
2014 Meling DD, McDougle DR, Das A. CYP2J2 epoxygenase membrane anchor plays an important role in facilitating electron transfer from CPR. Journal of Inorganic Biochemistry. 142: 47-53. PMID 25450017 DOI: 10.1016/J.Jinorgbio.2014.09.016  0.777
2014 McDougle DR, Kambalyal A, Meling DD, Das A. Endocannabinoids anandamide and 2-arachidonoylglycerol are substrates for human CYP2J2 epoxygenase. The Journal of Pharmacology and Experimental Therapeutics. 351: 616-27. PMID 25277139 DOI: 10.1124/Jpet.114.216598  0.793
2014 Das A, Varma SS, Mularczyk C, Meling DD. Functional investigations of thromboxane synthase (CYP5A1) in lipid bilayers of nanodiscs. Chembiochem : a European Journal of Chemical Biology. 15: 892-9. PMID 24623680 DOI: 10.1002/Cbic.201300646  0.821
2014 Orlando BJ, McDougle DR, Lucido MJ, Eng ET, Graham LA, Schneider C, Stokes DL, Das A, Malkowski MG. Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs. Archives of Biochemistry and Biophysics. 546: 33-40. PMID 24503478 DOI: 10.1016/J.Abb.2014.01.026  0.8
2013 Zelasko S, Palaria A, Das A. Optimizations to achieve high-level expression of cytochrome P450 proteins using Escherichia coli expression systems. Protein Expression and Purification. 92: 77-87. PMID 23973802 DOI: 10.1016/J.Pep.2013.07.017  0.346
2013 McDougle DR, Palaria A, Magnetta E, Meling DD, Das A. Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers. Protein Science : a Publication of the Protein Society. 22: 964-79. PMID 23661295 DOI: 10.1002/Pro.2280  0.798
2012 Marty MT, Das A, Sligar SG. Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs. Analytical and Bioanalytical Chemistry. 402: 721-9. PMID 22057720 DOI: 10.1007/S00216-011-5512-3  0.534
2011 Das A, Wei Y, Pelczer I, Hecht MH. Binding of small molecules to cavity forming mutants of a de novo designed protein. Protein Science : a Publication of the Protein Society. 20: 702-11. PMID 21328630 DOI: 10.1002/Pro.601  0.637
2010 Tark SH, Das A, Sligar S, Dravid VP. Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs. Nanotechnology. 21: 435502. PMID 20890017 DOI: 10.1088/0957-4484/21/43/435502  0.538
2009 Das A, Sligar SG. Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer. Biochemistry. 48: 12104-12. PMID 19908820 DOI: 10.1021/Bi9011435  0.569
2009 Das A, Zhao J, Schatz GC, Sligar SG, Van Duyne RP. Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy. Analytical Chemistry. 81: 3754-9. PMID 19364136 DOI: 10.1021/Ac802612Z  0.532
2008 Li H, Das A, Sibhatu H, Jamal J, Sligar SG, Poulos TL. Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential. The Journal of Biological Chemistry. 283: 34762-72. PMID 18852262 DOI: 10.1074/Jbc.M806949200  0.503
2008 Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy. Biochemistry. 47: 5156-67. PMID 18407660 DOI: 10.1021/Bi7025485  0.458
2008 Zhao J, Das A, Schatz GC, Sligar SG, Van Duyne RP. Resonance localized surface plasmon spectroscopy: Sensing substrate and inhibitor binding to cytochrome P450 Journal of Physical Chemistry C. 112: 13084-13088. DOI: 10.1021/Jp801719C  0.499
2008 Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy (Biochemistry (2008) 47, 18, (5156-5167)) Biochemistry. 47: 9344. DOI: 10.1021/Bi801317Z  0.431
2007 Das A, Grinkova YV, Sligar SG. Redox potential control by drug binding to cytochrome P450 3A4. Journal of the American Chemical Society. 129: 13778-9. PMID 17948999 DOI: 10.1021/Ja074864X  0.566
2007 Das A, Hecht MH. Peroxidase activity of de novo heme proteins immobilized on electrodes. Journal of Inorganic Biochemistry. 101: 1820-6. PMID 17765314 DOI: 10.1016/J.Jinorgbio.2007.07.024  0.548
2007 Kimmich N, Das A, Sevrioukova I, Meharenna Y, Sligar SG, Poulos TL. Electron transfer between cytochrome P450cin and its FMN-containing redox partner, cindoxin. The Journal of Biological Chemistry. 282: 27006-11. PMID 17606612 DOI: 10.1074/Jbc.M703790200  0.492
2006 Zhao J, Das A, Zhang X, Schatz GC, Sligar SG, Van Duyne RP. Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome p450. Journal of the American Chemical Society. 128: 11004-5. PMID 16925400 DOI: 10.1021/Ja0636082  0.507
2006 Das A, Trammell SA, Hecht MH. Electrochemical and ligand binding studies of a de novo heme protein. Biophysical Chemistry. 123: 102-12. PMID 16730114 DOI: 10.1016/J.Bpc.2006.04.011  0.562
2005 Hu Y, Das A, Hecht MH, Scoles G. Nanografting de novo proteins onto gold surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 9103-9. PMID 16171339 DOI: 10.1021/La046857H  0.541
2004 Hecht MH, Das A, Go A, Bradley LH, Wei Y. De novo proteins from designed combinatorial libraries. Protein Science : a Publication of the Protein Society. 13: 1711-23. PMID 15215517 DOI: 10.1110/Ps.04690804  0.765
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