Lark J. Perez, Ph.D. - Publications

Affiliations: 
2009 Yale University, New Haven, CT 
Area:
Organic Chemistry, Medicinal Chemistry

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Capilato JN, Pellegrinelli PJ, Bernard J, Schnorbus L, Philippi S, Mattiucci J, Hoy EP, Perez LJ. Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives. Organic & Biomolecular Chemistry. PMID 34086029 DOI: 10.1039/d1ob00786f  0.657
2020 Watve S, Barrasso K, Jung SA, Davis KJ, Hawver LA, Khataokar A, Palaganas RG, Neiditch MB, Perez LJ, Ng WL. Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host. Plos Pathogens. 16: e1008313. PMID 32059031 DOI: 10.1371/Journal.Ppat.1008313  0.341
2019 Flockton TR, Schnorbus L, Araujo A, Adams J, Hammel M, Perez LJ. Inhibition of Biofilm Formation with Surface Modified Polymeric Nanoparticles. Pathogens (Basel, Switzerland). 8. PMID 31022836 DOI: 10.3390/Pathogens8020055  0.31
2016 Capilato JN, Philippi SV, Reardon T, McConnell A, Oliver DC, Warren A, Adams JS, Wu C, Perez LJ. Development of a novel series of non-natural triaryl agonists and antagonists of the Pseudomonas aeruginosa LasR quorum sensing receptor. Bioorganic & Medicinal Chemistry. PMID 27825554 DOI: 10.1016/J.Bmc.2016.10.021  0.662
2016 Wu B, Capilato J, Pham MP, Walker J, Spur B, Rodriguez A, Perez LJ, Yin K. Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26965685 DOI: 10.1096/Fj.201500029R  0.641
2015 O'Brien KT, Noto JG, Nichols-O'Neill L, Perez LJ. Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa. Acs Medicinal Chemistry Letters. 6: 162-7. PMID 25699144 DOI: 10.1021/Ml500459F  0.358
2015 Lu HD, Spiegel AC, Hurley A, Perez LJ, Maisel K, Ensign LM, Hanes J, Bassler BL, Semmelhack MF, Prud'homme RK. Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles. Nano Letters. 15: 2235-41. PMID 25651002 DOI: 10.1021/Acs.Nanolett.5B00151  0.303
2014 Werner KM, Perez LJ, Ghosh R, Semmelhack MF, Bassler BL. Caenorhabditis elegans recognizes a bacterial quorum-sensing signal molecule through the AWCON neuron. The Journal of Biological Chemistry. 289: 26566-73. PMID 25092291 DOI: 10.1074/Jbc.M114.573832  0.303
2014 Perez LJ, Karagounis TK, Hurley A, Bassler BL, Semmelhack MF. Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae. Chemical Science (Royal Society of Chemistry : 2010). 5: 151-155. PMID 24436778 DOI: 10.1039/C3Sc52572D  0.35
2012 Perez LJ, Ng WL, Marano P, Brook K, Bassler BL, Semmelhack MF. Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. Journal of Medicinal Chemistry. 55: 9669-81. PMID 23092313 DOI: 10.1021/Jm300908T  0.382
2011 Bolitho ME, Perez LJ, Koch MJ, Ng WL, Bassler BL, Semmelhack MF. Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit. Bioorganic & Medicinal Chemistry. 19: 6906-18. PMID 22001326 DOI: 10.1016/J.Bmc.2011.09.021  0.36
2011 Ng WL, Perez LJ, Wei Y, Kraml C, Semmelhack MF, Bassler BL. Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Molecular Microbiology. 79: 1407-17. PMID 21219472 DOI: 10.1111/J.1365-2958.2011.07548.X  0.346
2011 Wei Y, Perez LJ, Ng WL, Semmelhack MF, Bassler BL. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. Acs Chemical Biology. 6: 356-65. PMID 21197957 DOI: 10.1021/Cb1003652  0.397
2010 Ng WL, Wei Y, Perez LJ, Cong J, Long T, Koch M, Semmelhack MF, Wingreen NS, Bassler BL. Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proceedings of the National Academy of Sciences of the United States of America. 107: 5575-80. PMID 20212168 DOI: 10.1073/Pnas.1001392107  0.361
2009 Perez LJ, Shimp HL, Micalizio GC. Stereoselective synthesis of trisubstituted (E,E)-1,3-dienes by the site-selective reductive cross-coupling of internal alkynes with terminal alkynes: a fragment coupling reaction for natural product synthesis. The Journal of Organic Chemistry. 74: 7211-9. PMID 19722544 DOI: 10.1021/Jo901451C  0.601
2008 Perez LJ, Micalizio GC. Titanium-mediated fragment union processes in complex molecule synthesis: Development of a branched reaction pathway of high step economy for the synthesis of complex and diverse polyketides Synthesis. 0627-0648. DOI: 10.1055/S-2008-1032160  0.623
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