Kevin W. Williams, Ph.D. - Publications

Affiliations: 
2001-2006 Neuroscience Tulane University, New Orleans, LA, United States 
 2006- Internal Medicine - Division of Hypothalamic Research University of Texas Southwestern Medical Center, Dallas, TX, United States 
Website:
http://www.utsouthwestern.edu/labs/williams/

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nickolas T, ... ... Williams KW, et al. Corrigendum: MC4R-dependent suppression of appetite by bone-derived lipocalin 2. Nature. 546: 440. PMID 28617454 DOI: 10.1038/nature22808  1
2017 Shen WJ, Yao T, Kong X, Williams KW, Liu T. Melanocortin neurons: multiple routes to regulation of metabolism. Biochimica Et Biophysica Acta. PMID 28499988 DOI: 10.1016/j.bbadis.2017.05.007  1
2017 Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nicholas T, ... ... Williams KW, et al. MC4R-dependent suppression of appetite by bone-derived lipocalin 2. Nature. PMID 28273060 DOI: 10.1038/nature21697  1
2017 Kong X, Williams KW, Liu T. Genetic Mouse Models: The Powerful Tools to Study Fat Tissues. Methods in Molecular Biology (Clifton, N.J.). 1566: 99-107. PMID 28244044 DOI: 10.1007/978-1-4939-6820-6_10  1
2017 Gaykema RP, Newmyer BA, Ottolini M, Raje V, Warthen DM, Lambeth PS, Niccum M, Yao T, Huang Y, Schulman IG, Harris TE, Patel MK, Williams KW, Scott MM. Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight. The Journal of Clinical Investigation. PMID 28218622 DOI: 10.1172/JCI81335  1
2017 Gao Y, Yao T, Deng Z, Sohn JW, Sun J, Huang Y, Kong X, Yu KJ, Wang RT, Chen H, Guo H, Yan J, Cunningham KA, Chang Y, Liu T, ... Williams KW, et al. TrpC5 Mediates Acute Leptin and Serotonin Effects via Pomc Neurons. Cell Reports. 18: 583-592. PMID 28099839 DOI: 10.1016/j.celrep.2016.12.072  1
2016 Yao T, Deng Z, Gao Y, Sun J, Kong X, Huang Y, He Z, Xu Y, Chang Y, Yu KJ, Findley BG, Berglund ED, Wang RT, Guo H, Chen H, ... ... Williams KW, et al. Ire1α in Pomc Neurons is Required for Thermogenesis and Glycemia. Diabetes. PMID 28028078 DOI: 10.2337/db16-0533  1
2016 Sun J, Gao Y, Yao T, Huang Y, He Z, Kong X, Yu KJ, Wang RT, Guo H, Yan J, Chang Y, Chen H, Scherer PE, Liu T, Williams KW. Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons. Molecular Metabolism. 5: 882-91. PMID 27689001 DOI: 10.1016/j.molmet.2016.08.007  1
2016 Sohn JW, Oh Y, Kim KW, Lee S, Williams KW, Elmquist JK. Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons. Molecular Metabolism. 5: 669-79. PMID 27656404 DOI: 10.1016/j.molmet.2016.06.004  1
2016 Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, ... ... Williams KW, et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metabolism. 24: 420-433. PMID 27626200 DOI: 10.1016/j.cmet.2016.08.005  1
2015 Yang D, Liu T, Williams KW. Motivation to Eat-AgRP Neurons and Homeostatic Need. Cell Metabolism. 22: 62-3. PMID 26154054 DOI: 10.1016/j.cmet.2015.06.018  1
2015 Gautron L, Elmquist JK, Williams KW. Neural control of energy balance: translating circuits to therapies. Cell. 161: 133-45. PMID 25815991 DOI: 10.1016/j.cell.2015.02.023  1
2014 Scott MM, Xu Y, Elias CF, Williams KW. Central regulation of food intake, body weight, energy expenditure, and glucose homeostasis. Frontiers in Neuroscience. 8: 384. PMID 25520610 DOI: 10.3389/fnins.2014.00384  1
2014 Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, et al. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metabolism. 20: 471-82. PMID 25017942 DOI: 10.1016/j.cmet.2014.06.002  1
2014 Berglund ED, Liu T, Kong X, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Williams KW, Olson DP, Scherer PE, Lowell BB, Elmquist JK. Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia. Nature Neuroscience. 17: 911-3. PMID 24908101 DOI: 10.1038/nn.3737  1
2014 Frazao R, Dungan Lemko HM, da Silva RP, Ratra DV, Lee CE, Williams KW, Zigman JM, Elias CF. Estradiol modulates Kiss1 neuronal response to ghrelin. American Journal of Physiology. Endocrinology and Metabolism. 306: E606-14. PMID 24473434 DOI: 10.1152/ajpendo.00211.2013  1
2014 Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis (Journal of Clinical Investigation (2014) 124, 4 (1868) DOI: 10.1172/JCI75669) Journal of Clinical Investigation. 124: 1868.  1
2013 Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. The Journal of Clinical Investigation. 123: 5061-70. PMID 24177424 DOI: 10.1172/JCI70338  1
2013 Liu T, Elmquist JK, Williams KW. Mrap2: an accessory protein linked to obesity. Cell Metabolism. 18: 309-11. PMID 24011068 DOI: 10.1016/j.cmet.2013.08.016  1
2013 Sohn JW, Elmquist JK, Williams KW. Neuronal circuits that regulate feeding behavior and metabolism. Trends in Neurosciences. 36: 504-12. PMID 23790727 DOI: 10.1016/j.tins.2013.05.003  1
2013 Cravo RM, Frazao R, Perello M, Osborne-Lawrence S, Williams KW, Zigman JM, Vianna C, Elias CF. Leptin signaling in Kiss1 neurons arises after pubertal development. Plos One. 8: e58698. PMID 23505551 DOI: 10.1371/journal.pone.0058698  1
2013 Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/JNEUROSCI.1610-12.2013  1
2013 Sohn JW, Harris LE, Berglund ED, Liu T, Vong L, Lowell BB, Balthasar N, Williams KW, Elmquist JK. Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. Cell. 152: 612-9. PMID 23374353 DOI: 10.1016/j.cell.2012.12.022  1
2012 Williams KW, Elmquist JK. From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior. Nature Neuroscience. 15: 1350-5. PMID 23007190 DOI: 10.1038/nn.3217  1
2012 Cui H, Sohn JW, Gautron L, Funahashi H, Williams KW, Elmquist JK, Lutter M. Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. The Journal of Comparative Neurology. 520: 4168-83. PMID 22605619 DOI: 10.1002/cne.23145  1
2012 Sohn JW, Williams KW. Functional heterogeneity of arcuate nucleus pro-opiomelanocortin neurons: implications for diverging melanocortin pathways. Molecular Neurobiology. 45: 225-33. PMID 22328135 DOI: 10.1007/s12035-012-8240-6  1
2011 Williams KW, Sohn JW, Donato J, Lee CE, Zhao JJ, Elmquist JK, Elias CF. The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13147-56. PMID 21917798 DOI: 10.1523/JNEUROSCI.2602-11.2011  1
2011 Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 71: 488-97. PMID 21835345 DOI: 10.1016/j.neuron.2011.06.012  1
2011 Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, et al. High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience. 14: 911-8. PMID 21642975 DOI: 10.1038/nn.2847  1
2011 Scott MM, Williams KW, Rossi J, Lee CE, Elmquist JK. Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice. The Journal of Clinical Investigation. 121: 2413-21. PMID 21606595 DOI: 10.1172/JCI43703  1
2011 Fukuda M, Williams KW, Gautron L, Elmquist JK. Induction of leptin resistance by activation of cAMP-Epac signaling. Cell Metabolism. 13: 331-9. PMID 21356522 DOI: 10.1016/j.cmet.2011.01.016  1
2011 Williams KW, Elmquist JK. Lighting up the hypothalamus: coordinated control of feeding behavior. Nature Neuroscience. 14: 277-8. PMID 21346745 DOI: 10.1038/nn0311-277  1
2011 Williams KW, Scott MM, Elmquist JK. Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network. European Journal of Pharmacology. 660: 2-12. PMID 21211525 DOI: 10.1016/j.ejphar.2010.11.042  1
2011 Kim KW, Sohn JW, Kohno D, Xu Y, Williams K, Elmquist JK. SF-1 in the ventral medial hypothalamic nucleus: a key regulator of homeostasis. Molecular and Cellular Endocrinology. 336: 219-23. PMID 21111025 DOI: 10.1016/j.mce.2010.11.019  1
2010 Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nature Neuroscience. 13: 1457-9. PMID 21037584 DOI: 10.1038/nn.2664  1
2010 Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, et al. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metabolism. 11: 286-97. PMID 20374961 DOI: 10.1016/j.cmet.2010.03.002  1
2010 Williams KW, Margatho LO, Lee CE, Choi M, Lee S, Scott MM, Elias CF, Elmquist JK. Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2472-9. PMID 20164331 DOI: 10.1523/JNEUROSCI.3118-09.2010  1
2009 Gao H, Glatzer NR, Williams KW, Derbenev AV, Liu D, Smith BN. Morphological and electrophysiological features of motor neurons and putative interneurons in the dorsal vagal complex of rats and mice. Brain Research. 1291: 40-52. PMID 19619517 DOI: 10.1016/j.brainres.2009.07.024  1
2009 Williams KW, Scott MM, Elmquist JK. From observation to experimentation: leptin action in the mediobasal hypothalamus. The American Journal of Clinical Nutrition. 89: 985S-990S. PMID 19176744 DOI: 10.3945/ajcn.2008.26788D  1
2008 Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 60: 582-9. PMID 19038216 DOI: 10.1016/j.neuron.2008.09.033  1
2008 Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, Elmquist JK, Coppari R. Brain SIRT1: anatomical distribution and regulation by energy availability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9989-96. PMID 18829956 DOI: 10.1523/JNEUROSCI.3257-08.2008  1
2008 Hill JW, Williams KW, Ye C, Luo J, Balthasar N, Coppari R, Cowley MA, Cantley LC, Lowell BB, Elmquist JK. Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. The Journal of Clinical Investigation. 118: 1796-805. PMID 18382766 DOI: 10.1172/JCI32964  1
2007 Williams KW, Coppari R, Elmquist JK. "AMPing up" our understanding of the hypothalamic control of energy balance. The Journal of Clinical Investigation. 117: 2089-92. PMID 17671647 DOI: 10.1172/JCI32975  1
2007 Williams KW, Zsombok A, Smith BN. Rapid inhibition of neurons in the dorsal motor nucleus of the vagus by leptin. Endocrinology. 148: 1868-81. PMID 17194747 DOI: 10.1210/en.2006-1098  1
2006 Williams KW, Smith BN. Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour. The Journal of Physiology. 573: 395-412. PMID 16581866 DOI: 10.1113/jphysiol.2006.106336  1
2004 Davis SF, Derbenev AV, Williams KW, Glatzer NR, Smith BN. Excitatory and inhibitory local circuit input to the rat dorsal motor nucleus of the vagus originating from the nucleus tractus solitarius. Brain Research. 1017: 208-17. PMID 15261116 DOI: 10.1016/j.brainres.2004.05.049  1
2003 Davis SF, Williams KW, Xu W, Glatzer NR, Smith BN. Selective enhancement of synaptic inhibition by hypocretin (orexin) in rat vagal motor neurons: implications for autonomic regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3844-54. PMID 12736355  1
Show low-probability matches.