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Soo S. Kang, Ph.D. - Publications

Affiliations: 
2009 Chemistry Purdue University, West Lafayette, IN, United States 
Area:
organic synthesis, bioorganic chemistry and molecular modeling
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cooper G, Kang S, Perez-Rosello T, Guzman JN, Galtieri D, Xie Z, Kondapalli J, Mordell J, Silverman RB, Surmeier DJ. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca1.3 L-Type Calcium Channels. Acs Chemical Biology. PMID 32881483 DOI: 10.1021/Acschembio.0C00577  0.681
2020 Kim D, Kim SY, Kim D, Yoon NG, Yun J, Hong KB, Lee C, Lee JH, Kang BH, Kang S. Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorganic Chemistry. 101: 103901. PMID 32590225 DOI: 10.1016/J.Bioorg.2020.103901  0.708
2020 Tran VH, La MT, Kang S, Kim HK. Practical direct synthesis of N-aryl-substituted azacycles from N-alkyl protected arylamines using TiCl and DBU. Organic & Biomolecular Chemistry. PMID 32573603 DOI: 10.1039/D0Ob00880J  0.649
2020 Rey S, Maton G, Satake S, Llano I, Kang S, Surmeier DJ, Silverman RB, Collin T. Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons. Journal of Neurochemistry. PMID 32491217 DOI: 10.1111/Jnc.15100  0.663
2019 Jung S, Yoon NG, Yang S, Kim D, Lee WS, Hong KB, Lee C, Kang BH, Lee JH, Kang S. Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1. Bioorganic & Medicinal Chemistry Letters. 126809. PMID 31839539 DOI: 10.1016/J.Bmcl.2019.126809  0.706
2019 Lee SY, Kim H, Li CM, Kang J, Najafov A, Jung M, Kang S, Wang S, Yuan J, Jung YK. Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3. Cell Death & Disease. 10: 923. PMID 31801942 DOI: 10.1038/S41419-019-2146-4  0.664
2019 Hieu Tran V, Park H, Park J, Kwon YD, Kang S, Ho Jung J, Chang KA, Chul Lee B, Lee SY, Kang S, Kim HK. Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamide. Bioorganic & Medicinal Chemistry. PMID 31353076 DOI: 10.1016/J.Bmc.2019.07.036  0.654
2019 La MT, Kang S, Kim HK. Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers using POCl. The Journal of Organic Chemistry. PMID 31039311 DOI: 10.1021/Acs.Joc.9B00377  0.656
2018 Hong KB, Kim D, Kim BK, Woo SY, Lee JH, Han SH, Bae GU, Kang S. CF₃-Substituted Mollugin 2-(4-Morpholinyl)-ethyl ester as a Potential Anti-inflammatory Agent with Improved Aqueous Solubility and Metabolic Stability. Molecules (Basel, Switzerland). 23. PMID 30110934 DOI: 10.3390/Molecules23082030  0.658
2018 Macalino SJY, Basith S, Clavio NAB, Chang H, Kang S, Choi S. Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery. Molecules (Basel, Switzerland). 23. PMID 30082644 DOI: 10.3390/Molecules23081963  0.667
2018 Basith S, Cui M, Macalino SJY, Park J, Clavio NAB, Kang S, Choi S. Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design. Frontiers in Pharmacology. 9: 128. PMID 29593527 DOI: 10.3389/Fphar.2018.00128  0.667
2018 Kang S, La MT, Kim H. Convenient metal-free direct oxidative amidation of aldehyde using dibromoisocyanuric acid under mild conditions Tetrahedron Letters. 59: 3541-3546. DOI: 10.1016/J.Tetlet.2018.08.026  0.306
2017 Park HK, Jeong H, Ko E, Lee G, Lee JE, Lee SK, Lee AJ, Im JY, Hu S, Kim SH, Lee JH, Lee C, Kang S, Kang BH. Paralog specificity determines subcellular distribution, action mechanism, and anticancer activity of TRAP1 inhibitors. Journal of Medicinal Chemistry. PMID 28816449 DOI: 10.1021/Acs.Jmedchem.7B00978  0.696
2016 Li H, Wang HY, Kang S, Silverman RB, Poulos TL. Electrostatic control of isoform selective inhibitor binding in nitric oxide synthase. Biochemistry. PMID 27250740 DOI: 10.1021/Acs.Biochem.6B00261  0.72
2016 Xie CB, Haris Shaikh L, Garg S, Tanriver G, Teo AE, Zhou J, Maniero C, Zhao W, Kang S, Silverman RB, Azizan EA, Brown MJ. Regulation of aldosterone secretion by Cav1.3. Scientific Reports. 6: 24697. PMID 27098837 DOI: 10.1038/Srep24697  0.687
2016 Cinelli MA, Li H, Pensa AV, Kang S, Roman LJ, Martásek P, Poulos TL, Silverman RB. Correction to Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. Journal of Medicinal Chemistry. PMID 26807481 DOI: 10.1021/Acs.Jmedchem.6B00036  0.705
2015 Cinelli MA, Li H, Pensa AV, Kang S, Roman LJ, Martásek P, Poulos TL, Silverman RB. Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. Journal of Medicinal Chemistry. PMID 26469213 DOI: 10.1021/Acs.Jmedchem.5B01330  0.74
2015 Teixeira-Castro A, Jalles A, Esteves S, Kang S, da Silva Santos L, Silva-Fernandes A, Neto MF, Brielmann RM, Bessa C, Duarte-Silva S, Miranda A, Oliveira S, Neves-Carvalho A, Bessa J, Summavielle T, et al. Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease. Brain : a Journal of Neurology. PMID 26373603 DOI: 10.1093/Brain/Awv262  0.674
2015 Kang S, Li H, Tang W, Martásek P, Roman LJ, Poulos TL, Silverman RB. 2-Aminopyridines with a Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity. Journal of Medicinal Chemistry. PMID 26120733 DOI: 10.1021/Acs.Jmedchem.5B00573  0.707
2015 Holden JK, Kang S, Beasley FC, Cinelli MA, Li H, Roy SG, Dejam D, Edinger AL, Nizet V, Silverman RB, Poulos TL. Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus. Chemistry & Biology. 22: 785-92. PMID 26091171 DOI: 10.1016/J.Chembiol.2015.05.013  0.693
2015 Holden JK, Dejam D, Lewis MC, Huang H, Kang S, Jing Q, Xue F, Silverman RB, Poulos TL. Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase. Biochemistry. 54: 4075-82. PMID 26062720 DOI: 10.1021/Acs.Biochem.5B00431  0.725
2015 Holden JK, Kang S, Hollingsworth SA, Li H, Lim N, Chen S, Huang H, Xue F, Tang W, Silverman RB, Poulos TL. Structure-based design of bacterial nitric oxide synthase inhibitors. Journal of Medicinal Chemistry. 58: 994-1004. PMID 25522110 DOI: 10.1021/Jm501723P  0.725
2015 Kang S, Watanabe M, Jacobs JC, Yamaguchi M, Dahesh S, Nizet V, Leyh TS, Silverman RB. Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability. European Journal of Medicinal Chemistry. 90: 448-61. PMID 25461893 DOI: 10.1016/J.Ejmech.2014.11.040  0.683
2014 Li H, Jamal J, Delker S, Plaza C, Ji H, Jing Q, Huang H, Kang S, Silverman RB, Poulos TL. The mobility of a conserved tyrosine residue controls isoform-dependent enzyme-inhibitor interactions in nitric oxide synthases. Biochemistry. 53: 5272-9. PMID 25089924 DOI: 10.1021/Bi500561H  0.709
2014 Kang S, Tang W, Li H, Chreifi G, Martásek P, Roman LJ, Poulos TL, Silverman RB. Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity Journal of Medicinal Chemistry. 57: 4382-4396. PMID 24758147 DOI: 10.1021/Jm5004182  0.73
2014 Mukherjee P, Cinelli MA, Kang S, Silverman RB. Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain. Chemical Society Reviews. 43: 6814-38. PMID 24549364 DOI: 10.1039/C3Cs60467E  0.705
2013 Holden JK, Li H, Jing Q, Kang S, Richo J, Silverman RB, Poulos TL. Structural and biological studies on bacterial nitric oxide synthase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 110: 18127-31. PMID 24145412 DOI: 10.1073/Pnas.1314080110  0.712
2013 Walia A, Kang S, Silverman RB. Microwave-assisted protection of primary amines as 2,5-dimethylpyrroles and their orthogonal deprotection Journal of Organic Chemistry. 78: 10931-10937. PMID 24073706 DOI: 10.1021/Jo401778E  0.648
2013 St John SE, Jensen KC, Kang S, Chen Y, Calamini B, Mesecar AD, Lipton MA. Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2. Bioorganic & Medicinal Chemistry. 21: 6022-37. PMID 23953689 DOI: 10.1016/J.Bmc.2013.07.037  0.764
2013 Kang S, Cooper G, Dunne SF, Luan CH, James Surmeier D, Silverman RB. Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics. Bioorganic & Medicinal Chemistry. 21: 4365-73. PMID 23688558 DOI: 10.1016/J.Bmc.2013.04.054  0.703
2013 Kang S, Cooper G, Dunne SF, Luan CH, Surmeier DJ, Silverman RB. Structure-activity relationship of N,N'-disubstituted pyrimidinetriones as Ca(V)1.3 calcium channel-selective antagonists for Parkinson's disease. Journal of Medicinal Chemistry. 56: 4786-97. PMID 23651412 DOI: 10.1021/Jm4005048  0.722
2012 Kang S, Cooper G, Dunne SF, Dusel B, Luan CH, Surmeier DJ, Silverman RB. CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease. Nature Communications. 3: 1146. PMID 23093183 DOI: 10.1038/Ncomms2149  0.677
2010 Chang CC, Cao S, Kang S, Kai L, Tian X, Pandey P, Dunne SF, Luan CH, Surmeier DJ, Silverman RB. Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2. Bioorganic & Medicinal Chemistry. 18: 3147-58. PMID 20382537 DOI: 10.1016/J.Bmc.2010.03.038  0.666
2009 Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorganic & Medicinal Chemistry. 17: 1044-54. PMID 18487053 DOI: 10.1016/J.Bmc.2008.04.031  0.61
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