Seyun Kim - Related publications

Johns Hopkins University, Baltimore, MD 
Cell signaling
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Mitchell K, Mikwar M, Da Fonte D, Lu C, Tao B, Peng D, Udeesha Erandani WKC, Hu W, Trudeau VL. Secretoneurin is a secretogranin-2 derived hormonal peptide in vertebrate neuroendocrine systems. General and Comparative Endocrinology. 113588. PMID 32828813 DOI: 10.1016/j.ygcen.2020.113588   
2020 Zhao L, Geng T, Sun K, Su S, Zhao Y, Bao N, Pan L, Sun H, Li M. Proteomic analysis reveals the molecular mechanism of Hippophae rhamnoides polysaccharide intervention in LPS-induced inflammation of IPEC-J2 cells in piglets. International Journal of Biological Macromolecules. PMID 32888998 DOI: 10.1016/j.ijbiomac.2020.08.235   
2020 He Y, Wu Y, Mei B, Fang X, Cai G, Cai N, Wu Q, Huang Z, Ge C, Liang H, Zhang B, Chen X, Chu L. A small nucleolar RNA, SNORD126, promotes adipogenesis in cells and rats by activating the PI3K-AKT pathway. Journal of Cellular Physiology. PMID 32960468 DOI: 10.1002/jcp.30066   
2020 Liu R, Chen Y, Liu G, Li C, Song Y, Cao Z, Li W, Hu J, Lu C, Liu Y. PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death & Disease. 11: 797. PMID 32973135 DOI: 10.1038/s41419-020-02998-6   
2020 Hu B, Zhang Y, Deng T, Gu J, Liu J, Yang H, Xu Y, Yan Y, Yang F, Zhang H, Jin Y, Zhou J. PDPK1 regulates autophagosome biogenesis by binding to PIK3C3. Autophagy. PMID 32876514 DOI: 10.1080/15548627.2020.1817279   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y   
2020 Colella B, Colardo M, Iannone G, Contadini C, Saiz-Ladera C, Fuoco C, Barilà D, Velasco G, Segatto M, Di Bartolomeo S. mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells. Cancers. 12. PMID 32823532 DOI: 10.3390/cancers12082266   
2020 Schönholzer MT, Migliavacca J, Alvarez E, Santhana Kumar K, Neve A, Gries A, Ma M, Grotzer MA, Baumgartner M. Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion. Neoplasia (New York, N.Y.). 22: 470-483. PMID 32818841 DOI: 10.1016/j.neo.2020.07.006   
2020 Sukumaran A, Choi K, Dasgupta B. Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes. Frontiers in Cell and Developmental Biology. 8: 671. PMID 32903688 DOI: 10.3389/fcell.2020.00671   
2020 Chun KS, Jang JH, Kim DH. Perspectives Regarding the Intersections between STAT3 and Oxidative Metabolism in Cancer. Cells. 9. PMID 33003453 DOI: 10.3390/cells9102202   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 He P, Mann-Collura O, Fling J, Edara N, Hetz R, Razzaque MS. High phosphate actively induces cytotoxicity by rewiring pro-survival and pro-apoptotic signaling networks in HEK293 and HeLa cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32892444 DOI: 10.1096/fj.202000799RR   
2020 Lacey BM, Xu Z, Chai X, Laskey J, Fradera X, Mittal P, Mishra S, Piesvaux J, Saradjian P, Shaffer L, Vassileva G, Gerdt C, Wang Y, Ferguson H, Smith DM, et al. Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors. Slas Discovery : Advancing Life Sciences R & D. 2472555220952071. PMID 32844715 DOI: 10.1177/2472555220952071   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Amraei R, Alwani T, Ho RX, Aryan Z, Wang S, Rahimi N. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy. The Journal of Biological Chemistry. PMID 32978258 DOI: 10.1074/jbc.RA120.014790   
2020 Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. Biomolecules & Therapeutics. PMID 33073770 DOI: 10.4062/biomolther.2020.153   
2020 Sundar V, Vimal S, Sai Mithlesh MS, Dutta A, Tamizhselvi R, Manickam V. Transcriptional cyclin-dependent kinases as the mediators of inflammation-a review. Gene. 145200. PMID 33031895 DOI: 10.1016/j.gene.2020.145200   
2020 Shie PH, Yang CP, Huang GJ, Wang SY, Kuo YH. Sinensol-C Isolated from Inhibits Adipogenesis in 3T3-L1 Cells through the Regulation of Adipogenic Transcription Factors and AMPK Activation. Molecules (Basel, Switzerland). 25. PMID 32937822 DOI: 10.3390/molecules25184204   
2020 Hirata Y, Nada Y, Yamada Y, Toyama T, Fukunaga K, Hwang GW, Noguchi T, Matsuzawa A. Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X-ROS-ASK1-p38 Axis in Microglial Cell Lines. Biological & Pharmaceutical Bulletin. 43: 1562-1569. PMID 32999166 DOI: 10.1248/bpb.b20-00409   
2020 Nam HH, Kim JS, Lee J, Seo YH, Kim HS, Ryu SM, Choi G, Moon BC, Lee AY. Pharmacological Effects of against Gastritis Using a Network Pharmacology Approach. Biomolecules. 10. PMID 32916904 DOI: 10.3390/biom10091298   
2020 Melick CH, Jewell JL. Regulation of mTORC1 by Upstream Stimuli. Genes. 11. PMID 32854217 DOI: 10.3390/genes11090989   
2020 Rödiger A, Galonska J, Bergner E, Agne B, Helm S, Alseekh S, Fernie AR, Thieme D, Hoehenwarter W, Hause G, Pfannschmidt T, Baginsky S. Working day and night: plastid casein kinase 2 catalyses phosphorylation of proteins with diverse functions in light- and dark-adapted plastids. The Plant Journal : For Cell and Molecular Biology. PMID 32745315 DOI: 10.1111/tpj.14944   
2020 Choi H, Roh J. LH-induced Transcriptional Regulation of Expression in Granulosa Cells Occurs via the cAMP/PKA Pathway and Requires a Putative Sp1 Binding Site. International Journal of Molecular Sciences. 21. PMID 33036290 DOI: 10.3390/ijms21197385   
2020 Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. The Biochemical Journal. PMID 32869834 DOI: 10.1042/BCJ20200555   
2020 Shaaya M, Fauser J, Zhurikhina A, Conage-Pough JE, Huyot V, Brennan M, Flower CT, Matsche J, Khan S, Natarajan V, Rehman J, Kota P, White FM, Tsygankov D, Karginov AV. Light-Regulated allosteric switch enables temporal and subcellular control of enzyme activity. Elife. 9. PMID 32965214 DOI: 10.7554/eLife.60647   
2020 Lee SW, Commisso C. Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras. Biochemical and Biophysical Research Communications. PMID 32972751 DOI: 10.1016/j.bbrc.2020.09.029   
2020 CB Hanna, D Mudaliar, K John, CL Allen, L Sun, JE Hawkinson, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT. Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis Biology of Reproduction. 103. PMID 32667031 DOI: 10.1093/biolre/ioaa097   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 da Silva Rosa SC, Martens MD, Field JT, Nguyen L, Kereliuk SM, Hai Y, Chapman D, Diehl-Jones W, Aliani M, West AR, Thliveris J, Ghavami S, Rampitsch C, Dolinsky VW, Gordon JW. BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation. Autophagy. 1-16. PMID 33044904 DOI: 10.1080/15548627.2020.1821548   
2020 Hoy JJ, Salinas Parra N, Park J, Kuhn S, Iglesias-Bartolome R. Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32830375 DOI: 10.1096/fj.202001515R   
2020 Yang HW, Jung Y, Kim HD, Kim J. Ribosomal protein S3-derived repair domain peptides regulate UV-induced matrix metalloproteinase-1. Biochemical and Biophysical Research Communications. 530: 149-154. PMID 32828277 DOI: 10.1016/j.bbrc.2020.06.094   
2020 Brian BF, Guerrero CR, Freedman TS. Immunopharmacology and Quantitative Analysis of Tyrosine Kinase Signaling. Current Protocols in Immunology. 130: e104. PMID 32931655 DOI: 10.1002/cpim.104   
2020 Thompson PA, Eam B, Young NP, Fish S, Chen J, Barrera M, Howard H, Sung E, Parra A, Staunton J, Chiang GG, Gerson-Gurwitz A, Wegerski CJ, Nevarez A, Clarine J, et al. Targeting oncogene mRNA translation in B cell malignancies with eFT226, a potent and selective inhibitor of eIF4A1. Molecular Cancer Therapeutics. PMID 33037136 DOI: 10.1158/1535-7163.MCT-19-0973   
2020 Su Y, Wang X, Guo Z, Wang J. Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition. Oncogene. PMID 32879443 DOI: 10.1038/s41388-020-01446-1   
2020 Song P, Song B, Liu J, Wang X, Nan X, Wang J. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 32974862 DOI: 10.1007/s12094-020-02486-5   
2020 Ren Y, Song X, Tan L, Guo C, Wang M, Liu H, Cao Z, Li Y, Peng C. A Review of the Pharmacological Properties of Psoralen. Frontiers in Pharmacology. 11: 571535. PMID 33013413 DOI: 10.3389/fphar.2020.571535   
2020 Lee DS, Kim JE. P2 × 7 Receptor Inhibits Astroglial Autophagy via Regulating FAK- and PHLPP1/2-Mediated AKT-S473 Phosphorylation Following Kainic Acid-Induced Seizures. International Journal of Molecular Sciences. 21. PMID 32899862 DOI: 10.3390/ijms21186476   
2020 Zhang X, Zhang Y, Ji Z, Wang F, Zhang L, Song M, Li H. Oxidative damage mechanism in Saccharomyces cerevisiae cells exposed to tetrachlorobisphenol A. Environmental Toxicology and Pharmacology. 103507. PMID 33007436 DOI: 10.1016/j.etap.2020.103507   
2020 Huang JB, Hsu SP, Pan HY, Chen SD, Chen SF, Lin TK, Liu XP, Li JH, Chen NC, Liou CW, Hsu CY, Chuang HY, Chuang YC. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International Journal of Molecular Sciences. 21. PMID 33008083 DOI: 10.3390/ijms21197247   
2020 Shakeel I, Basheer N, Hasan GM, Afzal M, Hassan MI. Polo-like Kinase 1 as an emerging drug target: Structure, function and therapeutic implications. Journal of Drug Targeting. 1-43. PMID 32886539 DOI: 10.1080/1061186X.2020.1818760   
2020 Wang Q, Zhang Y, Zhu J, Zheng H, Chen S, Chen L, Yang HS. IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas. Signal Transduction and Targeted Therapy. 5: 153. PMID 32843616 DOI: 10.1038/s41392-020-0204-0   
2020 Xu X, Lemmens LJM, den Hamer A, Merkx M, Ottmann C, Brunsveld L. Modular bioengineered kinase sensors scaffold protein-mediated split-luciferase complementation. Chemical Science. 11: 5532-5536. PMID 32874496 DOI: 10.1039/d0sc00074d   
2020 Mittal S, Kamath A, Joseph AM, Rajala MS. PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants. International Journal of Oncology. PMID 32945365 DOI: 10.3892/ijo.2020.5112   
2020 Gladulich LFH, Xie J, Jensen KB, Kamei M, Paes-de-Carvalho R, Cossenza M, Proud CG. Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation. Journal of Neurochemistry. PMID 32892352 DOI: 10.1111/jnc.15178   
2020 Takahara T, Amemiya Y, Sugiyama R, Maki M, Shibata H. Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes. Journal of Biomedical Science. 27: 87. PMID 32799865 DOI: 10.1186/s12929-020-00679-2   
2020 de Assis LJ, Silva LP, Liu L, Schmitt K, Valerius O, Braus GH, Ries LNA, Goldman GH. The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi. Plos Genetics. 16: e1008996. PMID 32841242 DOI: 10.1371/journal.pgen.1008996   
2020 Kang BW, Chau I. Molecular target: pan-AKT in gastric cancer. Esmo Open. 5. PMID 32948630 DOI: 10.1136/esmoopen-2020-000728