Christopher D. Fleming, Ph.D. - Publications
Affiliations: | 2007 | Biochemistry and Biophysics | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Structural Studies of Dynamic Cellular ProcessesYear | Citation | Score | |||
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2010 | Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR. Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin. Molecular Pharmacology. 77: 508-16. PMID 20051531 DOI: 10.1124/Mol.109.062356 | 0.545 | |||
2007 | Fleming CD, Edwards CC, Kirby SD, Maxwell DM, Potter PM, Cerasoli DM, Redinbo MR. Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun. Biochemistry. 46: 5063-71. PMID 17407327 DOI: 10.1021/Bi700246N | 0.586 | |||
2005 | Huang H, Fleming CD, Nishi K, Redinbo MR, Hammock BD. Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases. Chemical Research in Toxicology. 18: 1371-7. PMID 16167828 DOI: 10.1021/Tx050072+ | 0.486 | |||
2005 | Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard-Williams EL, Potter PM, Redinbo MR. Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. Journal of Molecular Biology. 352: 165-77. PMID 16081098 DOI: 10.1016/J.Jmb.2005.07.016 | 0.467 | |||
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