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Pauline Bourbon, Ph.D. - Publications

Affiliations: 
2013 University of Notre Dame, Notre Dame, IN, United States 
Area:
Drug Design & Discovery, Synthetic Chemistry
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Pearson GL, Mellett N, Chu KY, Cantley J, Davenport A, Bourbon P, Cosner CC, Helquist P, Meikle PJ, Biden TJ. Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells. Diabetologia. 57: 129-39. PMID 24149836 DOI: 10.1007/S00125-013-3083-X  0.606
2013 Bourbon P, Peng Q, Ferraudi G, Stauffacher C, Wiest O, Helquist P. Development of carbamate-tethered coumarins as phototriggers for caged nicotinamide. Bioorganic & Medicinal Chemistry Letters. 23: 6321-4. PMID 24125882 DOI: 10.1016/J.Bmcl.2013.09.067  0.538
2013 Bourbon P, Peng Q, Ferraudi G, Stauffacher C, Wiest O, Helquist P. Synthesis and photochemical behavior of coumarin-caged cholesterol. Bioorganic & Medicinal Chemistry Letters. 23: 2162-5. PMID 23434228 DOI: 10.1016/J.Bmcl.2013.01.095  0.555
2012 Bourbon P, Peng Q, Ferraudi G, Stauffacher C, Wiest O, Helquist P. Synthesis, photophysical, photochemical, and computational studies of coumarin-labeled nicotinamide derivatives. The Journal of Organic Chemistry. 77: 2756-62. PMID 22360284 DOI: 10.1021/Jo2025527  0.496
2011 Pierre F, Chua PC, O'Brien SE, Siddiqui-Jain A, Bourbon P, Haddach M, Michaux J, Nagasawa J, Schwaebe MK, Stefan E, Vialettes A, Whitten JP, Chen TK, Darjania L, Stansfield R, et al. Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Molecular and Cellular Biochemistry. 356: 37-43. PMID 21755459 DOI: 10.1007/S11010-011-0956-5  0.322
2011 Pipalia NH, Cosner CC, Huang A, Chatterjee A, Bourbon P, Farley N, Helquist P, Wiest O, Maxfield FR. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 108: 5620-5. PMID 21436030 DOI: 10.1073/Pnas.1014890108  0.647
2011 Pierre F, O'Brien SE, Haddach M, Bourbon P, Schwaebe MK, Stefan E, Darjania L, Stansfield R, Ho C, Siddiqui-Jain A, Streiner N, Rice WG, Anderes K, Ryckman DM. Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral properties. Bioorganic & Medicinal Chemistry Letters. 21: 1687-91. PMID 21316963 DOI: 10.1016/J.Bmcl.2011.01.091  0.301
2011 Pierre F, Chua PC, O'Brien SE, Siddiqui-Jain A, Bourbon P, Haddach M, Michaux J, Nagasawa J, Schwaebe MK, Stefan E, Vialettes A, Whitten JP, Chen TK, Darjania L, Stansfield R, et al. Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer. Journal of Medicinal Chemistry. 54: 635-54. PMID 21174434 DOI: 10.1021/Jm101251Q  0.331
2009 Cosner CC, Markiewicz JT, Bourbon P, Mariani CJ, Wiest O, Rujoi M, Rosenbaum AI, Huang AY, Maxfield FR, Helquist P. Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 52: 6494-8. PMID 19772346 DOI: 10.1021/Jm900707N  0.523
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