Charles B. Nemeroff - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Biological Psychiatry, Depression

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Year Citation  Score
2021 Durand D, Calfagno TM, Wong A, Newport DJ, Nemeroff CB, Dunlop BW, Harvey PD. Effects of Vortioxetine Versus Placebo on Cognition and Functional Capacity in Adults With Posttraumatic Stress Disorder. Journal of Clinical Psychopharmacology. PMID 34145182 DOI: 10.1097/JCP.0000000000001414  0.548
2021 Dunlop BW, Rakofsky JJ, Newport DJ, Mletzko-Crowe T, Barone K, Nemeroff CB, Harvey PD. Efficacy of Vortioxetine Monotherapy for Posttraumatic Stress Disorder: A Randomized, Placebo-Controlled Trial. Journal of Clinical Psychopharmacology. PMID 33587394 DOI: 10.1097/JCP.0000000000001363  0.578
2021 Lopez JP, Brivio E, Santambrogio A, De Donno C, Kos A, Peters M, Rost N, Czamara D, Brückl TM, Roeh S, Pöhlmann ML, Engelhardt C, Ressle A, Stoffel R, Tontsch A, ... ... Nemeroff CB, et al. Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. Science Advances. 7. PMID 33571131 DOI: 10.1126/sciadv.abe4497  0.446
2021 Czamara D, Tissink E, Tuhkanen J, Martins J, Awaloff Y, Drake AJ, Khulan B, Palotie A, Winter SM, Nemeroff CB, Craighead WE, Dunlop BW, Mayberg HS, Kinkead B, Mathew SJ, et al. Combined effects of genotype and childhood adversity shape variability of DNA methylation across age. Translational Psychiatry. 11: 88. PMID 33526782 DOI: 10.1038/s41398-020-01147-z  0.698
2020 Medina-Rodriguez EM, Madorma D, O'Connor G, Mason BL, Han D, Deo SK, Oppenheimer M, Nemeroff CB, Trivedi MH, Daunert S, Beurel E. Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice. The American Journal of Psychiatry. appiajp202019090960. PMID 32731813 DOI: 10.1176/Appi.Ajp.2020.19090960  0.327
2020 Kamiya M, Sabia HD, Marella J, Fava M, Nemeroff CB, Umeuchi H, Iijima M, Chaki S, Nishino I. Efficacy and safety of TS-121, a novel vasopressin V receptor antagonist, as adjunctive treatment for patients with major depressive disorder: A randomized, double-blind, placebo-controlled study. Journal of Psychiatric Research. 128: 43-51. PMID 32521250 DOI: 10.1016/j.jpsychires.2020.05.017  0.341
2020 Dwyer JB, Aftab A, Widge A, Rodriguez CI, Carpenter LL, Nemeroff CB, Kalin NH. Hormonal Treatments for Major Depressive Disorder: State of the Art. The American Journal of Psychiatry. appiajp202019080848. PMID 32456504 DOI: 10.1176/Appi.Ajp.2020.19080848  0.38
2020 Vega ML, Newport GC, Bozhdaraj D, Saltz SB, Nemeroff CB, Newport DJ. Implementation of Advanced Methods for Reproductive Pharmacovigilance in Autism: A Meta-Analysis of the Effects of Prenatal Antidepressant Exposure. The American Journal of Psychiatry. appiajp202018070766. PMID 32375539 DOI: 10.1176/appi.ajp.2020.18070766  0.578
2019 Dunlop BW, Still S, LoParo D, Aponte-Rivera V, Johnson BN, Schneider RL, Nemeroff CB, Mayberg HS, Craighead WE. Somatic symptoms in treatment-naïve Hispanic and non-Hispanic patients with major depression. Depression and Anxiety. PMID 31830355 DOI: 10.1002/Da.22984  0.313
2019 Thomas M, Coope A, Falkenberg C, Dunlop BW, Czamara D, Provencal N, Craighead WE, Mayberg HS, Nemeroff CB, Binder EB, Nieratschker V. Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms. Journal of Psychiatric Research. 120: 154-162. PMID 31683097 DOI: 10.1016/j.jpsychires.2019.10.019  0.506
2019 Jabbi M, Nemeroff CB. Convergent neurobiological predictors of mood and anxiety symptoms and treatment response. Expert Review of Neurotherapeutics. PMID 31096806 DOI: 10.1080/14737175.2019.1620604  0.309
2019 Widge AS, Rodriguez CI, Carpenter LL, Kalin NH, McDonald W, Nemeroff CB. EEG Biomarkers for Treatment Response Prediction in Major Depressive Illness. The American Journal of Psychiatry. 176: 82. PMID 30848947 DOI: 10.1176/Appi.Ajp.2018.1760101  0.31
2019 Dunlop BW, LoParo D, Kinkead B, Mletzko-Crowe T, Cole SP, Nemeroff CB, Mayberg HS, Craighead WE. Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression. The American Journal of Psychiatry. appiajp201818091075. PMID 30764648 DOI: 10.1176/appi.ajp.2018.18091075  0.643
2018 Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB. DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder. Clinical Epigenetics. 10: 136. PMID 30390684 DOI: 10.1186/s13148-018-0569-x  0.497
2018 Widge AS, Bilge MT, Montana R, Chang W, Rodriguez CI, Deckersbach T, Carpenter LL, Kalin NH, Nemeroff CB. Electroencephalographic Biomarkers for Treatment Response Prediction in Major Depressive Illness: A Meta-Analysis. The American Journal of Psychiatry. appiajp201817121358. PMID 30278789 DOI: 10.1176/Appi.Ajp.2018.17121358  0.314
2018 Kelley ME, Dunlop BW, Nemeroff CB, Lori A, Carrillo-Roa T, Binder EB, Kutner MH, Rivera VA, Craighead WE, Mayberg HS. Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse. Depression and Anxiety. PMID 30260539 DOI: 10.1002/da.22832  0.494
2018 Ahmadi N, Moss L, Hauser P, Nemeroff C, Atre-Vaidya N. Clinical outcome of maintenance electroconvulsive therapy in comorbid Posttraumatic Stress Disorder and major depressive disorder. Journal of Psychiatric Research. 105: 132-136. PMID 30219562 DOI: 10.1016/J.Jpsychires.2018.08.023  0.329
2018 Dunlop BW, Polychroniou PE, Rakofsky JJ, Nemeroff CB, Craighead WE, Mayberg HS. Suicidal ideation and other persisting symptoms after CBT or antidepressant medication treatment for major depressive disorder. Psychological Medicine. 1-10. PMID 30207254 DOI: 10.1017/S0033291718002568  0.328
2018 Syed SA, Beurel E, Loewenstein DA, Lowell JA, Craighead WE, Dunlop BW, Mayberg HS, Dhabhar F, Dietrich WD, Keane RW, de Rivero Vaccari JP, Nemeroff CB. Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response. Neuron. PMID 30146307 DOI: 10.1016/J.Neuron.2018.08.001  0.331
2018 Coplan JD, Lu D, El Sehamy AM, Tang C, Jackowski AP, Abdallah CG, Nemeroff CB, Owens MJ, Mathew SJ, Gorman JM. Early Life Stress Associated With Increased Striatal -Acetyl-Aspartate: Cerebrospinal Fluid Corticotropin-Releasing Factor Concentrations, Hippocampal Volume, Body Mass and Behavioral Correlates. Chronic Stress (Thousand Oaks, Calif.). 2. PMID 29963652  0.643
2018 Coplan JD, Rozenboym AV, Fulton SL, Panthangi V, Tang J, Thiramangalakdi L, Perera TD, Liu Y, Kamran H, Owens MJ, Nemeroff CB, Rosenblum LA, Kral JG, Salciccioli L, Lazar J. Reduced left ventricular dimension and function following early life stress: A thrifty phenotype hypothesis engendering risk for mood and anxiety disorders. Neurobiology of Stress. 8: 202-210. PMID 29888314 DOI: 10.1016/j.ynstr.2017.01.001  0.648
2018 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, et al. Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 19: 61. PMID 29792225 DOI: 10.1186/S13059-018-1441-1  0.571
2018 Pape J, Carrillo-Roa T, Wiechmann T, Roeh S, Rothbaum B, Nemeroff C, Czamara D, Zannas A, Iosifescu D, Mathew S, Neylan T, Mayberg H, Dunlop B, Binder E. F179. Epigenetic Biomarkers in Women With Posttraumatic Stress Disorder After CRF1 Receptor Antagonist Treatment Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.793  0.486
2017 Dunlop BW, Cole SP, Nemeroff CB, Mayberg HS, Craighead WE. Differential change on depressive symptom factors with antidepressant medication and cognitive behavior therapy for major depressive disorder. Journal of Affective Disorders. 229: 111-119. PMID 29306690 DOI: 10.1016/j.jad.2017.12.035  0.349
2017 Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, et al. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. Plos Biology. 15: e2002690. PMID 29283992 DOI: 10.1371/Journal.Pbio.2002690  0.499
2017 O'Connell CP, Goldstein-Piekarski AN, Nemeroff CB, Schatzberg AF, Debattista C, Carrillo-Roa T, Binder EB, Dunlop BW, Craighead WE, Mayberg HS, Williams LM. Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein. The American Journal of Psychiatry. appiajp201717020172. PMID 29241359 DOI: 10.1176/Appi.Ajp.2017.17020172  0.499
2017 Berg JM, Kennedy JC, Dunlop BW, Ramirez CL, Stewart LM, Nemeroff CB, Mayberg HS, Craighead WE. The Structure of Personality Disorders within a Depressed Sample: Implications for Personalizing Treatment. Personalized Medicine in Psychiatry. 1: 59-64. PMID 28944312 DOI: 10.1016/j.pmip.2016.12.005  0.311
2017 Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS. Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder. Biological Psychiatry. PMID 28793974 DOI: 10.1016/j.biopsych.2017.06.024  0.715
2017 Dunlop BW, Kelley ME, Aponte-Rivera V, Mletzko-Crowe T, Kinkead B, Ritchie JC, Nemeroff CB, Craighead WE, Mayberg HS. Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study. The American Journal of Psychiatry. appiajp201616050517. PMID 28335624 DOI: 10.1176/appi.ajp.2016.16050517  0.717
2017 Dunlop BW, Rajendra JK, Craighead WE, Kelley ME, McGrath CL, Choi KS, Kinkead B, Nemeroff CB, Mayberg HS. Functional Connectivity of the Subcallosal Cingulate Cortex And Differential Outcomes to Treatment With Cognitive-Behavioral Therapy or Antidepressant Medication for Major Depressive Disorder. The American Journal of Psychiatry. appiajp201616050518. PMID 28335622 DOI: 10.1176/appi.ajp.2016.16050518  0.643
2017 Syed SA, Smith EL, Batuman O, Rosenblum LA, Owens MJ, Nemeroff CB, Coplan JD. Adult Glucocorticoid Receptor mRNA Expression Volatility in Response to an Acute Stressor and Juvenile CSF Corticotropin-Releasing Factor: A Pilot Neurodevelopmental Study. Neuroscience Letters. PMID 28330718 DOI: 10.1016/j.neulet.2017.03.017  0.663
2017 Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, Summergrad P, Nemeroff CB. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. Jama Psychiatry. PMID 28249076 DOI: 10.1001/jamapsychiatry.2017.0080  0.31
2017 Castro MN, Vigo DE, Gustafson DR, Vila-Pérez I, Massaro P, García C, Nemeroff CB, Guinjoan SM, Ladrón-de-Guevara MS. Acute and six-month depression-related abnormalities in the sleep-wake rhythm of cardiac autonomic activity in survivors of acute coronary syndromes Personalized Medicine in Psychiatry. 4: 13-18. DOI: 10.1016/J.Pmip.2017.06.001  0.309
2017 Pape J, Carrillo-Roa T, Iosifescu D, Mathew S, Neylan T, Nemeroff C, Mayberg H, Dunlop B, Binder E. 549. DNA Methylation Biomarkers and Treatment Effects of a Corticotropin Releasing Hormone Type 1 Receptor Antagonist in a Biologically-Defined Subset of PTSD-Patients Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.1157  0.491
2016 Goldstein-Piekarski AN, Korgaonkar MS, Green E, Suppes T, Schatzberg AF, Hastie T, Nemeroff CB, Williams LM. Human amygdala engagement moderated by early life stress exposure is a biobehavioral target for predicting recovery on antidepressants. Proceedings of the National Academy of Sciences of the United States of America. 113: 11955-11960. PMID 27791054 DOI: 10.1073/Pnas.1606671113  0.339
2016 Sanders J, Nemeroff C. The CRF System as a Therapeutic Target for Neuropsychiatric Disorders. Trends in Pharmacological Sciences. PMID 27717506 DOI: 10.1016/j.tips.2016.09.004  0.327
2016 Newport DJ, Schatzberg AF, Nemeroff CB. WHITHER KETAMINE AS AN ANTIDEPRESSANT: PANACEA OR TOXIN? Depression and Anxiety. 33: 685-8. PMID 27459676 DOI: 10.1002/da.22535  0.601
2016 Williams LM, Debattista C, Duchemin AM, Schatzberg AF, Nemeroff CB. Childhood trauma predicts antidepressant response in adults with major depression: data from the randomized international study to predict optimized treatment for depression. Translational Psychiatry. 6: e799. PMID 27138798 DOI: 10.1038/Tp.2016.61  0.344
2016 Menke A, Arloth J, Best J, Namendorf C, Gerlach T, Czamara D, Lucae S, Dunlop BW, Crowe TM, Garlow SJ, Nemeroff CB, Ritchie JC, Craighead WE, Mayberg HS, Rex-Haffner M, et al. Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests. Psychoneuroendocrinology. 69: 161-171. PMID 27107207 DOI: 10.1016/j.psyneuen.2016.04.003  0.649
2016 Newport DJ, Nemeroff CB. Response to Zhang and Ho: Addressing Ketamine's Use in Depression. The American Journal of Psychiatry. 173: 431-2. PMID 27035536 DOI: 10.1176/appi.ajp.2016.15111401r  0.61
2016 Houtepen LC, Vinkers CH, Carrillo-Roa T, Hiemstra M, van Lier PA, Meeus W, Branje S, Heim CM, Nemeroff CB, Mill J, Schalkwyk LC, Creyghton MP, Kahn RS, Joëls M, Binder EB, et al. Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nature Communications. 7: 10967. PMID 26997371 DOI: 10.1038/Ncomms10967  0.597
2016 Carrillo-Roa T, Dunlop B, McGrath C, Czamara D, Zaanas A, Kelley M, Nemeroff C, Craighead W, Mayberg H, Binder E. P.3.004 Neuroimaging derived polygenic scores predict outcomes to psychotherapy and medication treatments for depression European Neuropsychopharmacology. 26: S48-S49. DOI: 10.1016/S0924-977X(16)70054-X  0.481
2015 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, et al. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 16: 266. PMID 26673150 DOI: 10.1186/s13059-015-0828-5  0.584
2015 Ahmadi N, Moss L, Simon E, Nemeroff CB, Atre-Vaidya N. EFFICACY AND LONG-TERM CLINICAL OUTCOME OF COMORBID POSTTRAUMATIC STRESS DISORDER AND MAJOR DEPRESSIVE DISORDER AFTER ELECTROCONVULSIVE THERAPY. Depression and Anxiety. PMID 26555786 DOI: 10.1002/da.22451  0.32
2015 Newport DJ, Carpenter LL, McDonald WM, Potash JB, Tohen M, Nemeroff CB. Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression. The American Journal of Psychiatry. 172: 950-66. PMID 26423481 DOI: 10.1176/Appi.Ajp.2015.15040465  0.608
2015 Chastain LG, Qu H, Bourke CH, Iuvone PM, Dobner PR, Nemeroff CB, Kinkead B. Striatal dopamine receptor plasticity in neurotensin deficient mice. Behavioural Brain Research. 280: 160-71. PMID 25449842 DOI: 10.1016/J.Bbr.2014.11.014  0.78
2015 Zannas A, Carrillo-Roa T, Iurato S, Arloth J, Röh S, Ressler K, Nemeroff C, Smith A, Bradley B, Heim C, Lange J, Brückl T, Ising M, Wray N, Erhardt A, et al. P.1.a.031 Lifetime stress accelerates epigenetic aging European Neuropsychopharmacology. 25. DOI: 10.1016/S0924-977X(15)30161-9  0.472
2015 Zannas A, Carrillo-Roa T, Iurato S, Ressler K, Nemeroff C, Smith A, Lange J, Bradley B, Heim C, Brückl T, Ising M, Wray N, Erhardt A, Binder E, Mehta D. Lifetime Stress Accelerates Epigenetic Aging European Psychiatry. 30: 799. DOI: 10.1016/S0924-9338(15)31949-0  0.599
2014 Coplan JD, Fathy HM, Jackowski AP, Tang CY, Perera TD, Mathew SJ, Martinez J, Abdallah CG, Dwork AJ, Pantol G, Carpenter D, Gorman JM, Nemeroff CB, Owens MJ, Kaffman A, et al. Early life stress and macaque amygdala hypertrophy: preliminary evidence for a role for the serotonin transporter gene. Frontiers in Behavioral Neuroscience. 8: 342. PMID 25339875 DOI: 10.3389/Fnbeh.2014.00342  0.644
2014 Myers AJ, Williams L, Gatt JM, McAuley-Clark EZ, Dobson-Stone C, Schofield PR, Nemeroff CB. Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stress. Journal of Psychiatric Research. 59: 93-100. PMID 25262417 DOI: 10.1016/J.Jpsychires.2014.08.021  0.354
2014 Cáceda R, Durand D, Cortes E, Prendes-Alvarez S, Moskovciak T, Harvey PD, Nemeroff CB. Impulsive choice and psychological pain in acutely suicidal depressed patients. Psychosomatic Medicine. 76: 445-51. PMID 24988311 DOI: 10.1097/Psy.0000000000000075  0.646
2014 Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS. Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial. Trials. 15: 240. PMID 24950747 DOI: 10.1186/1745-6215-15-240  0.71
2014 Sotelo JL, Musselman D, Nemeroff C. The biology of depression in cancer and the relationship between depression and cancer progression International Review of Psychiatry. 26: 16-30. PMID 24716498 DOI: 10.3109/09540261.2013.875891  0.642
2014 Nemeroff CB, Binder E. The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: toward elucidating the underlying neurobiological mechanisms. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 395-7. PMID 24655648 DOI: 10.1016/j.jaac.2014.02.004  0.492
2014 Cáceda R, Nemeroff CB, Harvey PD. Toward an understanding of decision making in severe mental illness. The Journal of Neuropsychiatry and Clinical Neurosciences. 26: 196-213. PMID 24599051 DOI: 10.1176/Appi.Neuropsych.12110268  0.647
2014 Chappell JC, Eisenhofer G, Owens MJ, Haber H, Lachno DR, Dean RA, Knadler MP, Nemeroff CB, Mitchell MI, Detke MJ, Iyengar S, Pangallo B, Lobo ED. Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects. Journal of Clinical Psychopharmacology. 34: 9-16. PMID 24346757 DOI: 10.1097/JCP.0000000000000061  0.638
2014 Zannas A, Klengel T, Nemeroff C, Carrillo-Roa T, Heim C, Bradley B, Ressler K, Binder E. P.1.a.003 Epigenetic regulation at the FKBP5 genetic locus by age and depressive phenotypes: implications for age-related disease European Neuropsychopharmacology. 24: S154. DOI: 10.1016/S0924-977X(14)70234-2  0.441
2013 Grieve SM, Korgaonkar MS, Etkin A, Harris A, Koslow SH, Wisniewski S, Schatzberg AF, Nemeroff CB, Gordon E, Williams LM. Brain imaging predictors and the international study to predict optimized treatment for depression: study protocol for a randomized controlled trial. Trials. 14: 224. PMID 23866851 DOI: 10.1186/1745-6215-14-224  0.323
2013 Heim CM, Mayberg HS, Mletzko T, Nemeroff CB, Pruessner JC. Decreased cortical representation of genital somatosensory field after childhood sexual abuse. The American Journal of Psychiatry. 170: 616-23. PMID 23732967 DOI: 10.1176/appi.ajp.2013.12070950  0.467
2013 Nye JA, Purselle D, Plisson C, Voll RJ, Stehouwer JS, Votaw JR, Kilts CD, Goodman MM, Nemeroff CB. Decreased brainstem and putamen SERT binding potential in depressed suicide attempters using [11C]-zient PET imaging. Depression and Anxiety. 30: 902-7. PMID 23526784 DOI: 10.1002/Da.22049  0.336
2013 Rustad JK, Musselman DL, Skyler JS, Matheson D, Delamater A, Kenyon NS, Cáceda R, Nemeroff CB. Decision-making in diabetes mellitus type 1. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 40-50. PMID 23487192 DOI: 10.1176/Appi.Neuropsych.12010016  0.742
2013 Flandreau EI, Bourke CH, Ressler KJ, Vale WW, Nemeroff CB, Owens MJ. Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala. Psychoneuroendocrinology. 38: 1349-61. PMID 23267723 DOI: 10.1016/J.Psyneuen.2012.11.020  0.798
2013 Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nature Neuroscience. 16: 33-41. PMID 23201972 DOI: 10.1038/Nn.3275  0.618
2013 Cisler JM, James GA, Tripathi S, Mletzko T, Heim C, Hu XP, Mayberg HS, Nemeroff CB, Kilts CD. Differential functional connectivity within an emotion regulation neural network among individuals resilient and susceptible to the depressogenic effects of early life stress. Psychological Medicine. 43: 507-18. PMID 22781311 DOI: 10.1017/S0033291712001390  0.525
2012 Dunlop BW, Binder EB, Cubells JF, Goodman MM, Kelley ME, Kinkead B, Kutner M, Nemeroff CB, Newport DJ, Owens MJ, Pace TW, Ritchie JC, Rivera VA, Westen D, Craighead WE, et al. Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial. Trials. 13: 106. PMID 22776534 DOI: 10.1186/1745-6215-13-106  0.789
2012 Nemeroff CB, Goldschmidt-Clermont PJ. Heartache and heartbreak--the link between depression and cardiovascular disease. Nature Reviews. Cardiology. 9: 526-39. PMID 22733213 DOI: 10.1038/Nrcardio.2012.91  0.327
2012 Nemeth CL, Shurte MS, McTigue DM, Nemeroff CB, Neigh GN. Microembolism infarcts lead to delayed changes in affective-like behaviors followed by spatial memory impairment. Behavioural Brain Research. 234: 259-66. PMID 22732259 DOI: 10.1016/J.Bbr.2012.06.014  0.713
2012 Parr LA, Boudreau M, Hecht E, Winslow JT, Nemeroff CB, Sánchez MM. Early life stress affects cerebral glucose metabolism in adult rhesus monkeys (Macaca mulatta). Developmental Cognitive Neuroscience. 2: 181-93. PMID 22682736 DOI: 10.1016/J.Dcn.2011.09.003  0.315
2012 Coccaro EF, Lee R, Owens MJ, Kinkead B, Nemeroff CB. Cerebrospinal fluid substance P-like immunoreactivity correlates with aggression in personality disordered subjects. Biological Psychiatry. 72: 238-43. PMID 22449753 DOI: 10.1016/J.Biopsych.2012.02.023  0.748
2012 Gould F, Clarke J, Heim C, Harvey PD, Majer M, Nemeroff CB. The effects of child abuse and neglect on cognitive functioning in adulthood. Journal of Psychiatric Research. 46: 500-6. PMID 22336639 DOI: 10.1016/J.Jpsychires.2012.01.005  0.495
2012 Cáceda R, Binder EB, Kinkead B, Nemeroff CB. The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion. Schizophrenia Research. 136: 88-95. PMID 22104138 DOI: 10.1016/j.schres.2011.10.013  0.799
2012 Flandreau EI, Ressler KJ, Owens MJ, Nemeroff CB. Chronic overexpression of corticotropin-releasing factor from the central amygdala produces HPA axis hyperactivity and behavioral anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus. Psychoneuroendocrinology. 37: 27-38. PMID 21616602 DOI: 10.1016/J.Psyneuen.2011.04.014  0.808
2012 Buss C, Pruessner JC, Mayberg H, Mletzko T, Nemeroff C, Heim C. Larger amygdala volumes after childhood trauma associated with depression and cortisol response to psychosocial stress in adulthood European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19445  0.534
2012 Rush A, Williams L, Koslow S, Wisniewski S, Cooper N, Nemeroff C, Schatzberg A, Gordon E. O-48 - The international study to predict optimized treatment - in depression: rational, design and initial findings European Psychiatry. 27: 1. DOI: 10.1016/S0924-9338(12)74148-2  0.328
2011 Hanson ND, Owens MJ, Nemeroff CB. Depression, antidepressants, and neurogenesis: a critical reappraisal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2589-602. PMID 21937982 DOI: 10.1038/npp.2011.220  0.762
2011 Dunlop BW, DeFife JA, Marx L, Garlow SJ, Nemeroff CB, Lilienfeld SO. The effects of sertraline on psychopathic traits. International Clinical Psychopharmacology. 26: 329-37. PMID 21909028 DOI: 10.1097/Yic.0B013E32834B80Df  0.337
2011 Hanson ND, Owens MJ, Boss-Williams KA, Weiss JM, Nemeroff CB. Several stressors fail to reduce adult hippocampal neurogenesis. Psychoneuroendocrinology. 36: 1520-9. PMID 21600697 DOI: 10.1016/j.psyneuen.2011.04.006  0.741
2011 Smith AK, Newport DJ, Ashe MP, Brennan PA, Laprairie JL, Calamaras M, Nemeroff CB, Ritchie JC, Cubells JF, Stowe ZN. Predictors of neonatal hypothalamic-pituitary-adrenal axis activity at delivery. Clinical Endocrinology. 75: 90-5. PMID 21521269 DOI: 10.1111/j.1365-2265.2011.03998.x  0.75
2011 Rustad JK, Musselman DL, Nemeroff CB. The relationship of depression and diabetes: pathophysiological and treatment implications. Psychoneuroendocrinology. 36: 1276-86. PMID 21474250 DOI: 10.1016/j.psyneuen.2011.03.005  0.623
2011 Coplan JD, Abdallah CG, Mathew SJ, Shungu DC, Mao X, Smith EL, Kaufman D, Gorman JM, Owens MJ, Nemeroff CB, Banerji MA, Rosenblum LA, Kral JG. Metabolic syndrome and neurometabolic asymmetry of hippocampus in adult bonnet monkeys. Physiology & Behavior. 103: 535-9. PMID 21459102 DOI: 10.1016/j.physbeh.2011.03.020  0.636
2011 Wade AG, Crawford GM, Nemeroff CB, Schatzberg AF, Schlaepfer T, McConnachie A, Haazen L, Buntinx E. Citalopram plus low-dose pipamperone versus citalopram plus placebo in patients with major depressive disorder: an 8-week, double-blind, randomized study on magnitude and timing of clinical response. Psychological Medicine. 41: 2089-97. PMID 21349239 DOI: 10.1017/S0033291711000158  0.329
2011 Hanson ND, Nemeroff CB, Owens MJ. Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus. The Journal of Pharmacology and Experimental Therapeutics. 337: 180-6. PMID 21220416 DOI: 10.1124/jpet.110.175372  0.745
2011 Williams LM, Rush AJ, Koslow SH, Wisniewski SR, Cooper NJ, Nemeroff CB, Schatzberg AF, Gordon E. International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol. Trials. 12: 4. PMID 21208417 DOI: 10.7490/F1000Research.1557.1  0.335
2011 Gutman DA, Owens MJ, Thrivikraman KV, Nemeroff CB. Persistent anxiolytic affects after chronic administration of the CRF₁ receptor antagonist R121919 in rats. Neuropharmacology. 60: 1135-41. PMID 20951149 DOI: 10.1016/j.neuropharm.2010.10.004  0.746
2011 Coplan JD, Abdallah CG, Kaufman J, Gelernter J, Smith EL, Perera TD, Dwork AJ, Kaffman A, Gorman JM, Rosenblum LA, Owens MJ, Nemeroff CB. Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: a pilot study. Psychoneuroendocrinology. 36: 289-93. PMID 20692103 DOI: 10.1016/J.Psyneuen.2010.07.011  0.657
2011 Dunlop BW, Betancourt Y, Binder EB, Heim C, Holsboer F, Ising M, McKenzie M, Mletzko T, Pfister H, Nemeroff CB, Craighead WE, Mayberg HS. Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder. Journal of Psychiatric Research. 45: 24-8. PMID 20488460 DOI: 10.1016/J.Jpsychires.2010.04.020  0.639
2011 Schienle A, Hettema JM, Cáceda R, Nemeroff CB. Neurobiology and genetics of generalized anxiety disorder Psychiatric Annals. 41: 111-123. DOI: 10.3928/00485713-20110203-10  0.624
2011 Gillespie CF, Binder EB, Holtzheimer PE, Nemeroff CB. Stress and the Impact of Personalized Medicine Integrative Neuroscience and Personalized Medicine. DOI: 10.1093/acprof:oso/9780195393804.003.0005  0.635
2011 Pace T, Heim C, Binder E, Nemeroff C, Miller A. 159. History of childhood trauma is associated with impaired glucocorticoid sensitivity in adulthood Brain, Behavior, and Immunity. 25: S225. DOI: 10.1016/j.bbi.2011.07.162  0.437
2010 Heim C, Shugart M, Craighead WE, Nemeroff CB. Neurobiological and psychiatric consequences of child abuse and neglect. Developmental Psychobiology. 52: 671-90. PMID 20882586 DOI: 10.1002/dev.20494  0.516
2010 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Clinics in Laboratory Medicine. 30: 865-91. PMID 20832657 DOI: 10.1016/j.cll.2010.07.006  0.503
2010 Gatt JM, Nemeroff CB, Schofield PR, Paul RH, Clark CR, Gordon E, Williams LM. Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. Biological Psychiatry. 68: 818-24. PMID 20728877 DOI: 10.1016/J.Biopsych.2010.06.025  0.34
2010 Gatt JM, Williams LM, Schofield PR, Dobson-Stone C, Paul RH, Grieve SM, Clark CR, Gordon E, Nemeroff CB. Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood. Depression and Anxiety. 27: 752-9. PMID 20694966 DOI: 10.1002/Da.20726  0.339
2010 Neigh GN, Owens MJ, Taylor WR, Nemeroff CB. Changes in the vascular area fraction of the hippocampus and amygdala are induced by prenatal dexamethasone and/or adult stress. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1100-4. PMID 20372172 DOI: 10.1038/jcbfm.2010.46  0.735
2010 Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB. Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Archives of General Psychiatry. 67: 369-79. PMID 20368512 DOI: 10.1001/Archgenpsychiatry.2010.18  0.722
2010 Martin EI, Ressler KJ, Jasnow AM, Dabrowska J, Hazra R, Rainnie DG, Nemeroff CB, Owens MJ. A novel transgenic mouse for gene-targeting within cells that express corticotropin-releasing factor. Biological Psychiatry. 67: 1212-6. PMID 20303068 DOI: 10.1016/J.Biopsych.2010.01.026  0.646
2010 Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB. Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 812-24. PMID 20029939 DOI: 10.1002/Ajmg.B.31052  0.692
2010 Binder EB, Nemeroff CB. The CRF system, stress, depression and anxiety-insights from human genetic studies. Molecular Psychiatry. 15: 574-88. PMID 20010888 DOI: 10.1038/mp.2009.141  0.549
2010 LaPrairie JL, Heim CM, Nemeroff CB. The neuroendocrine effects of early life trauma The Impact of Early Life Trauma On Health and Disease: the Hidden Epidemic. 157-165. DOI: 10.1017/CBO9780511777042.019  0.392
2010 Gutman DA, Nemeroff CB. Corticotropin-Releasing Factor Circuitry in the Brain - Relevance for Affective Disorders and Anxiety Encyclopedia of Stress. 630-634. DOI: 10.1016/B978-012373947-6.00454-2  0.5
2010 Gutman DA, Nemeroff CB. Neuroendocrinology of Affective Disorders Encyclopedia of Neuroscience. 355-366. DOI: 10.1016/B978-008045046-9.01185-2  0.451
2010 Neigh GN, Ritschel LA, Nemeroff CB. Biological consequences and transgenerational impact of violence and abuse Psychiatric Times. 27: 49-52.  0.496
2009 Bremner JD, Cheema FA, Ashraf A, Afzal N, Fani N, Reed L, Musselman DL, Ritchie JC, Faber T, Votaw JR, Nemeroff CB, Vaccarino V. Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with depression. Stress and Health : Journal of the International Society For the Investigation of Stress. 25: 267-278. PMID 34113216 DOI: 10.1002/smi.1246  0.699
2009 Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB, Ressler KJ, Binder EB. Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene. Frontiers in Behavioral Neuroscience. 3: 41. PMID 20161813 DOI: 10.3389/neuro.08.041.2009  0.744
2009 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. The Psychiatric Clinics of North America. 32: 549-75. PMID 19716990 DOI: 10.1016/j.psc.2009.05.004  0.503
2009 Neigh GN, Gillespie CF, Nemeroff CB. The neurobiological toll of child abuse and neglect. Trauma, Violence & Abuse. 10: 389-410. PMID 19661133 DOI: 10.1177/1524838009339758  0.728
2009 Neigh GN, Karelina K, Zhang N, Glasper ER, Owens MJ, Plotsky PM, Nemeroff CB, Devries AC. Cardiac arrest and cardiopulmonary resuscitation dysregulates the hypothalamic-pituitary-adrenal axis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1673-82. PMID 19553908 DOI: 10.1038/Jcbfm.2009.85  0.792
2009 Rakofsky JJ, Holtzheimer PE, Nemeroff CB. Emerging targets for antidepressant therapies. Current Opinion in Chemical Biology. 13: 291-302. PMID 19501541 DOI: 10.1016/J.Cbpa.2009.04.617  0.336
2009 Nemeroff CB, Owens MJ. The role of serotonin in the pathophysiology of depression: as important as ever. Clinical Chemistry. 55: 1578-9. PMID 19498050 DOI: 10.1373/clinchem.2009.123752  0.667
2009 Heim C, Nemeroff CB. Neurobiology of posttraumatic stress disorder. Cns Spectrums. 14: 13-24. PMID 19169190  0.433
2009 Gatt JM, Nemeroff CB, Dobson-Stone C, Paul RH, Bryant RA, Schofield PR, Gordon E, Kemp AH, Williams LM. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular Psychiatry. 14: 681-95. PMID 19153574 DOI: 10.1038/Mp.2008.143  0.346
2009 Heim C, Young LJ, Newport DJ, Mletzko T, Miller AH, Nemeroff CB. Lower CSF oxytocin concentrations in women with a history of childhood abuse. Molecular Psychiatry. 14: 954-8. PMID 18957940 DOI: 10.1038/mp.2008.112  0.691
2009 Keen-Rhinehart E, Michopoulos V, Toufexis DJ, Martin EI, Nair H, Ressler KJ, Davis M, Owens MJ, Nemeroff CB, Wilson ME. Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes. Molecular Psychiatry. 14: 37-50. PMID 18698320 DOI: 10.1038/Mp.2008.91  0.689
2009 Keitner GI, Garlow SJ, Ryan CE, Ninan PT, Solomon DA, Nemeroff CB, Keller MB. A randomized, placebo-controlled trial of risperidone augmentation for patients with difficult-to-treat unipolar, non-psychotic major depression. Journal of Psychiatric Research. 43: 205-14. PMID 18586273 DOI: 10.1016/j.jpsychires.2008.05.003  0.321
2009 Gutman DA, Coyer MJ, Boss-Williams KA, Owens MJ, Nemeroff CB, Weiss JM. Erratum to “Behavioral effects of the CRF1 receptor antagonist R121919 in rats selectively bred for high and low activity in the swim test” [Psychoneuroendocrinology 33(8) (2008) 1093–1101] Psychoneuroendocrinology. 34: 630-631. DOI: 10.1016/j.psyneuen.2009.01.008  0.71
2009 Bremner JD, Cheema FA, Ashraf A, Afzal N, Fani N, Reed L, Musselman DL, Ritchie JC, Faber T, Votaw JR, Nemeroff CB, Vaccarino V. Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with depression Stress and Health. 25: 267-278. DOI: 10.1002/Smi.1246  0.721
2008 Holtzheimer PE, Nemeroff CB. Novel targets for antidepressant therapies. Current Psychiatry Reports. 10: 465-73. PMID 18980729 DOI: 10.1007/S11920-008-0075-5  0.325
2008 Gutman DA, Coyer MJ, Boss-Williams KA, Owens MJ, Nemeroff CB, Weiss JM. Behavioral effects of the CRF1 receptor antagonist R121919 in rats selectively bred for high and low activity in the swim test. Psychoneuroendocrinology. 33: 1093-101. PMID 18676086 DOI: 10.1016/j.psyneuen.2008.05.003  0.71
2008 Heim C, Newport DJ, Mletzko T, Miller AH, Nemeroff CB. The link between childhood trauma and depression: insights from HPA axis studies in humans. Psychoneuroendocrinology. 33: 693-710. PMID 18602762 DOI: 10.1016/j.psyneuen.2008.03.008  0.718
2008 Owens MJ, Krulewicz S, Simon JS, Sheehan DV, Thase ME, Carpenter DJ, Plott SJ, Nemeroff CB. Estimates of serotonin and norepinephrine transporter inhibition in depressed patients treated with paroxetine or venlafaxine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3201-12. PMID 18418363 DOI: 10.1038/npp.2008.47  0.648
2008 Bruce EC, Guo Y, Lawson KC, Manatunga AK, Auyeung SF, McDonald WM, Rushing N, Brown AR, Gilles N, Emery M, Bonsall R, Porquez J, Stowe Z, Nemeroff CB, Musselman DL. Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. Psychosomatic Medicine. 70: 319-27. PMID 18378867 DOI: 10.1097/Psy.0B013E3181663580  0.735
2008 Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Schwartz AC, Cubells JF, Ressler KJ. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. Jama. 299: 1291-305. PMID 18349090 DOI: 10.1001/Jama.299.11.1291  0.726
2008 Ader M, Garvey WT, Phillips LS, Nemeroff CB, Gharabawi G, Mahmoud R, Greenspan A, Berry SA, Musselman DL, Morein J, Zhu Y, Mao L, Bergman RN. Ethnic heterogeneity in glucoregulatory function during treatment with atypical antipsychotics in patients with schizophrenia. Journal of Psychiatric Research. 42: 1076-85. PMID 18295798 DOI: 10.1016/J.Jpsychires.2008.01.004  0.615
2008 Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, et al. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Archives of General Psychiatry. 65: 190-200. PMID 18250257 DOI: 10.1001/Archgenpsychiatry.2007.26  0.805
2008 Kinkead B, Yan F, Owens MJ, Nemeroff CB. Endogenous neurotensin is involved in estrous cycle related alterations in prepulse inhibition of the acoustic startle reflex in female rats. Psychoneuroendocrinology. 33: 178-87. PMID 18155361 DOI: 10.1016/j.psyneuen.2007.11.005  0.751
2008 Zeng F, Jarkas N, Stehouwer JS, Voll RJ, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter. Bioorganic & Medicinal Chemistry. 16: 783-93. PMID 17983754 DOI: 10.1016/j.bmc.2007.10.025  0.607
2008 Carpenter LL, Bayat L, Moreno F, Kling MA, Price LH, Tyrka AR, Kinkead B, Owens MJ, Nemeroff CB. Decreased cerebrospinal fluid concentrations of substance P in treatment-resistant depression and lack of alteration after acute adjunct vagus nerve stimulation therapy. Psychiatry Research. 157: 123-9. PMID 17976740 DOI: 10.1016/J.Psychres.2007.04.016  0.777
2008 Nemeroff CB, Entsuah R, Benattia I, Demitrack M, Sloan DM, Thase ME. Comprehensive analysis of remission (COMPARE) with venlafaxine versus SSRIs. Biological Psychiatry. 63: 424-34. PMID 17888885 DOI: 10.1016/j.biopsych.2007.06.027  0.319
2008 Heim C, Mletzko T, Purselle D, Musselman DL, Nemeroff CB. The dexamethasone/corticotropin-releasing factor test in men with major depression: role of childhood trauma. Biological Psychiatry. 63: 398-405. PMID 17825799 DOI: 10.1016/j.biopsych.2007.07.002  0.723
2008 Penza KM, Heim C, Nemeroff CB. Loss and Deprivation: From Animal Models to Clinical Presentation Biology of Depression: From Novel Insights to Therapeutic Strategies. 689-714. DOI: 10.1002/9783527619672.ch28  0.757
2007 Kocsis JH, Thase ME, Trivedi MH, Shelton RC, Kornstein SG, Nemeroff CB, Friedman ES, Gelenberg AJ, Dunner DL, Hirschfeld RM, Rothschild AJ, Ferguson JM, Schatzberg AF, Zajecka JM, Pedersen RD, et al. Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study. The Journal of Clinical Psychiatry. 68: 1014-23. PMID 17685736 DOI: 10.4088/Jcp.V68N0706  0.317
2007 Felger JC, Alagbe O, Hu F, Mook D, Freeman AA, Sanchez MM, Kalin NH, Ratti E, Nemeroff CB, Miller AH. Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression. Biological Psychiatry. 62: 1324-33. PMID 17678633 DOI: 10.1016/J.Biopsych.2007.05.026  0.306
2007 Newport DJ, Calamaras MR, DeVane CL, Donovan J, Beach AJ, Winn S, Knight BT, Gibson BB, Viguera AC, Owens MJ, Nemeroff CB, Stowe ZN. Atypical antipsychotic administration during late pregnancy: placental passage and obstetrical outcomes. The American Journal of Psychiatry. 164: 1214-20. PMID 17671284 DOI: 10.1176/appi.ajp.2007.06111886  0.771
2007 Skelton KH, Oren D, Gutman DA, Easterling K, Holtzman SG, Nemeroff CB, Owens MJ. The CRF1 receptor antagonist, R121919, attenuates the severity of precipitated morphine withdrawal. European Journal of Pharmacology. 571: 17-24. PMID 17610870 DOI: 10.1016/j.ejphar.2007.05.041  0.812
2007 Lippmann M, Bress A, Nemeroff CB, Plotsky PM, Monteggia LM. Long-term behavioural and molecular alterations associated with maternal separation in rats. The European Journal of Neuroscience. 25: 3091-8. PMID 17561822 DOI: 10.1111/J.1460-9568.2007.05522.X  0.34
2007 Zeng F, Stehouwer JS, Jarkas N, Voll RJ, Williams L, Camp VM, Votaw JR, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of 2beta,3alpha-(substituted phenyl)nortropanes as potential norepinephrine transporter imaging agents. Bioorganic & Medicinal Chemistry Letters. 17: 3044-7. PMID 17446069 DOI: 10.1016/j.bmcl.2007.03.056  0.6
2007 Cáceda R, Kinkead B, Nemeroff CB. Involvement of neuropeptide systems in schizophrenia: human studies. International Review of Neurobiology. 78: 327-76. PMID 17349866 DOI: 10.1016/S0074-7742(06)78011-4  0.767
2007 Skelton KH, Gutman DA, Thrivikraman KV, Nemeroff CB, Owens MJ. The CRF1 receptor antagonist R121919 attenuates the neuroendocrine and behavioral effects of precipitated lorazepam withdrawal. Psychopharmacology. 192: 385-96. PMID 17297634 DOI: 10.1007/s00213-007-0713-3  0.812
2007 Gillespie CF, Nemeroff CB. Corticotropin-releasing factor and the psychobiology of early-life stress Current Directions in Psychological Science. 16: 85-89. DOI: 10.1111/J.1467-8721.2007.00481.X  0.648
2007 Keller M, Yan B, Musgnung J, Dunner D, Ferguson J, Friedman E, Gelenberg A, Hirschfeld R, Kocsis J, Kornstein S, Nemeroff C. Recurrence prevention in patients with recurrent major depression receiving 12 months of treatment with venlafaxine XR European Psychiatry. 22. DOI: 10.1016/J.Eurpsy.2007.01.804  0.303
2006 Holtzheimer PE, Nemeroff CB. Emerging treatments for depression. Expert Opinion On Pharmacotherapy. 7: 2323-39. PMID 17109609 DOI: 10.1517/14656566.7.17.2323  0.355
2006 Vergne DE, Nemeroff CB. The interaction of serotonin transporter gene polymorphisms and early adverse life events on vulnerability for major depression. Current Psychiatry Reports. 8: 452-7. PMID 17094925 DOI: 10.1007/s11920-006-0050-y  0.342
2006 Binder EB, Nemeroff CB. Implications for the practice of psychiatry. Progress in Brain Research. 158: 275-93. PMID 17027701 DOI: 10.1016/S0079-6123(06)58013-6  0.47
2006 Guo Y, Musselman DL, Manatunga AK, Gilles N, Lawson KC, Porter MR, McDaniel JS, Nemeroff CB. The diagnosis of major depression in patients with cancer: a comparative approach. Psychosomatics. 47: 376-84. PMID 16959925 DOI: 10.1176/Appi.Psy.47.5.376  0.641
2006 Pace TW, Mletzko TC, Alagbe O, Musselman DL, Nemeroff CB, Miller AH, Heim CM. Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. The American Journal of Psychiatry. 163: 1630-3. PMID 16946190 DOI: 10.1176/AJP.2006.163.9.1630  0.714
2006 Coplan JD, Smith EL, Altemus M, Mathew SJ, Perera T, Kral JG, Gorman JM, Owens MJ, Nemeroff CB, Rosenblum LA. Maternal-infant response to variable foraging demand in nonhuman primates: effects of timing of stressor on cerebrospinal fluid corticotropin-releasing factor and circulating glucocorticoid concentrations. Annals of the New York Academy of Sciences. 1071: 525-33. PMID 16891612 DOI: 10.1196/annals.1364.057  0.638
2006 Cáceda R, Kinkead B, Nemeroff CB. Neurotensin: role in psychiatric and neurological diseases. Peptides. 27: 2385-404. PMID 16891042 DOI: 10.1016/j.peptides.2006.04.024  0.766
2006 Shilling PD, Kinkead B, Murray T, Melendez G, Nemeroff CB, Feifel D. Upregulation of striatal dopamine-2 receptors in Brattleboro rats with prepulse inhibition deficits. Biological Psychiatry. 60: 1278-81. PMID 16814260 DOI: 10.1016/j.biopsych.2006.03.045  0.64
2006 Zeng F, Jarkas N, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Synthesis and monoamine transporter affinity of front bridged tricyclic 3beta-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2beta-position. Bioorganic & Medicinal Chemistry Letters. 16: 4661-3. PMID 16784855 DOI: 10.1016/j.bmcl.2006.05.098  0.598
2006 Rapaport MH, Gharabawi GM, Canuso CM, Mahmoud RA, Keller MB, Bossie CA, Turkoz I, Lasser RA, Loescher A, Bouhours P, Dunbar F, Nemeroff CB. Effects of risperidone augmentation in patients with treatment-resistant depression: Results of open-label treatment followed by double-blind continuation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2505-13. PMID 16760927 DOI: 10.1038/Sj.Npp.1301218  0.316
2006 Nemeroff CB, Mayberg HS, Krahl SE, McNamara J, Frazer A, Henry TR, George MS, Charney DS, Brannan SK. VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1345-55. PMID 16641939 DOI: 10.1038/Sj.Npp.1301082  0.316
2006 Kinkead B, Nemeroff CB. Novel treatments of schizophrenia: targeting the neurotensin system. Cns & Neurological Disorders Drug Targets. 5: 205-18. PMID 16611093 DOI: 10.2174/187152706776359655  0.601
2006 Geracioti TD, Carpenter LL, Owens MJ, Baker DG, Ekhator NN, Horn PS, Strawn JR, Sanacora G, Kinkead B, Price LH, Nemeroff CB. Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression. The American Journal of Psychiatry. 163: 637-43. PMID 16585438 DOI: 10.1176/Ajp.2006.163.4.637  0.774
2006 Neigh GN, Nemeroff CB. Reduced glucocorticoid receptors: consequence or cause of depression? Trends in Endocrinology and Metabolism: Tem. 17: 124-5. PMID 16574425 DOI: 10.1016/j.tem.2006.03.002  0.635
2006 Musselman DL, Somerset WI, Guo Y, Manatunga AK, Porter M, Penna S, Lewison B, Goodkin R, Lawson K, Lawson D, Evans DL, Nemeroff CB. A double-blind, multicenter, parallel-group study of paroxetine, desipramine, or placebo in breast cancer patients (stages I, II, III, and IV) with major depression. The Journal of Clinical Psychiatry. 67: 288-96. PMID 16566626 DOI: 10.4088/Jcp.V67N0217  0.702
2006 Welberg LA, Kinkead B, Thrivikraman K, Huerkamp MJ, Nemeroff CB, Plotsky PM. Ketamine-xylazine-acepromazine anesthesia and postoperative recovery in rats. Journal of the American Association For Laboratory Animal Science : Jaalas. 45: 13-20. PMID 16542037  0.588
2006 Kilts CD, Kelsey JE, Knight B, Ely TD, Bowman FD, Gross RE, Selvig A, Gordon A, Newport DJ, Nemeroff CB. The neural correlates of social anxiety disorder and response to pharmacotherapy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2243-53. PMID 16525417 DOI: 10.1038/sj.npp.1301053  0.599
2006 Holtzheimer PE, Nemeroff CB. Advances in the treatment of depression. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 42-56. PMID 16490412 DOI: 10.1016/J.Nurx.2005.12.007  0.36
2006 Nemeroff CB, Bremner JD, Foa EB, Mayberg HS, North CS, Stein MB. Posttraumatic stress disorder: a state-of-the-science review. Journal of Psychiatric Research. 40: 1-21. PMID 16242154 DOI: 10.1016/J.Jpsychires.2005.07.005  0.322
2006 Garlow SJ, Boone E, Kinkead B, Nemeroff CB. Genetic analysis of the hypothalamic neurotensin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 535-43. PMID 16123747 DOI: 10.1038/sj.npp.1300870  0.61
2006 Neigh G, Glasper E, Nemeroff C, Owens M, Plotsky P, DeVries A. Cardiac arrest and cardiopulmonary resuscitation increases CRF R1 receptor binding Frontiers in Neuroendocrinology. 27: 12-13. DOI: 10.1016/j.yfrne.2006.03.026  0.694
2006 Nemeroff CB, Neigh GN. Response to Rubin and Carroll and Van Den Eede et al Trends in Endocrinology and Metabolism. 17: 387. DOI: 10.1016/j.tem.2006.10.008  0.544
2006 Pace T, Alagbe O, Mletzko TM, Nemeroff CB, Musselman DL, Heim CM, Miller AH. Enhanced psychosocial stress-induced IL-6 responses are associated with attenuated stress-induced cortisol responses in patients with major depression and increased early life stress Brain, Behavior, and Immunity. 20: 54. DOI: 10.1016/j.bbi.2006.04.102  0.639
2006 Heim C, Bremner JD, Nemeroff CB. Trauma spectrum disorders Principles of Molecular Medicine. 1203-1210. DOI: 10.1007/978-1-59259-963-9_127  0.4
2006 Gutman DA, Gutman AR, Owens MJ, Nemeroff CB. Stress neurobiology and corticotropin-releasing factor Psychiatric Times. 23: 91-95.  0.696
2005 Nemeroff CB, Lieberman JA, Weiden PJ, Harvey PD, Newcomer JW, Schatzberg AF, Kilts CD, Daniel DG. From clinical research to clinical practice: a 4-year review of ziprasidone. Cns Spectrums. 10: 1-20. PMID 16381088 DOI: 10.1017/S1092852900019842  0.32
2005 Cáceda R, Kinkead B, Owens MJ, Nemeroff CB. Virally mediated increased neurotensin 1 receptor in the nucleus accumbens decreases behavioral effects of mesolimbic system activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11748-56. PMID 16354933 DOI: 10.1523/JNEUROSCI.4282-05.2005  0.79
2005 McIntyre RS, Konarski JZ, Mancini DA, Fulton KA, Parikh SV, Grigoriadis S, Grupp LA, Bakish D, Filteau MJ, Gorman C, Nemeroff CB, Kennedy SH. Measuring the severity of depression and remission in primary care: validation of the HAMD-7 scale. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 173: 1327-34. PMID 16301700 DOI: 10.1503/Cmaj.050786  0.322
2005 Davidson J, Watkins L, Owens M, Krulewicz S, Connor K, Carpenter D, Krishnan R, Nemeroff C. Effects of paroxetine and venlafaxine XR on heart rate variability in depression Journal of Clinical Psychopharmacology. 25: 480-484. PMID 16160626 DOI: 10.1097/01.jcp.0000177547.28961.03  0.653
2005 Coplan JD, Altemus M, Mathew SJ, Smith EL, Sharf B, Coplan PM, Kral JG, Gorman JM, Owens MJ, Nemeroff CB, Rosenblum LA. Synchronized maternal-infant elevations of primate CSF CRF concentrations in response to variable foraging demand. Cns Spectrums. 10: 530-6. PMID 16155510 DOI: 10.1017/S109285290001018X  0.63
2005 Nemeroff CB, Vale WW. The neurobiology of depression: inroads to treatment and new drug discovery. The Journal of Clinical Psychiatry. 66: 5-13. PMID 16124836  0.434
2005 Stowe ZN, Landry JC, Tang Z, Owens MJ, Kinkead B, Nemeroff CB. The electrophysiological effects of neurotensin on spontaneously active neurons in the nucleus accumbens: an in vivo study. Synapse (New York, N.Y.). 58: 165-72. PMID 16108007 DOI: 10.1002/syn.20190  0.78
2005 Evans DL, Charney DS, Lewis L, Golden RN, Gorman JM, Krishnan KR, Nemeroff CB, Bremner JD, Carney RM, Coyne JC, Delong MR, Frasure-Smith N, Glassman AH, Gold PW, Grant I, et al. Mood disorders in the medically ill: scientific review and recommendations. Biological Psychiatry. 58: 175-89. PMID 16084838 DOI: 10.1016/J.Biopsych.2005.05.001  0.728
2005 McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Votaw JR, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of trans-3-phenyl-1-indanamines as potential norepinephrine transporter imaging agents. Nuclear Medicine and Biology. 32: 593-605. PMID 16026706 DOI: 10.1016/j.nucmedbio.2005.04.012  0.746
2005 Pomara N, Willoughby LM, Ritchie JC, Sidtis JJ, Greenblatt DJ, Nemeroff CB. Sex-related elevation in cortisol during chronic treatment with alprazolam associated with enhanced cognitive performance. Psychopharmacology. 182: 414-9. PMID 16001108 DOI: 10.1007/s00213-005-0088-2  0.516
2005 Kinkead B, Dobner PR, Egnatashvili V, Murray T, Deitemeyer N, Nemeroff CB. Neurotensin-deficient mice have deficits in prepulse inhibition: restoration by clozapine but not haloperidol, olanzapine, or quetiapine. The Journal of Pharmacology and Experimental Therapeutics. 315: 256-64. PMID 15987829 DOI: 10.1124/jpet.105.087437  0.629
2005 Gillespie CF, Nemeroff CB. Hypercortisolemia and depression. Psychosomatic Medicine. 67: S26-8. PMID 15953796 DOI: 10.1097/01.Psy.0000163456.22154.D2  0.652
2005 Plotsky PM, Thrivikraman KV, Nemeroff CB, Caldji C, Sharma S, Meaney MJ. Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2192-204. PMID 15920504 DOI: 10.1038/sj.npp.1300769  0.366
2005 Bremner JD, Fani N, Ashraf A, Votaw JR, Brummer ME, Cummins T, Vaccarino V, Goodman MM, Reed L, Siddiq S, Nemeroff CB. Functional brain imaging alterations in acne patients treated with isotretinoin. The American Journal of Psychiatry. 162: 983-91. PMID 15863802 DOI: 10.1176/Appi.Ajp.162.5.983  0.332
2005 Jarkas N, Votaw JR, Voll RJ, Williams L, Camp VM, Owens MJ, Purselle DC, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters. Nuclear Medicine and Biology. 32: 211-24. PMID 15820756 DOI: 10.1016/j.nucmedbio.2004.11.007  0.621
2005 Golden RN, Gaynes BN, Ekstrom RD, Hamer RM, Jacobsen FM, Suppes T, Wisner KL, Nemeroff CB. The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. The American Journal of Psychiatry. 162: 656-62. PMID 15800134 DOI: 10.1176/appi.ajp.162.4.656  0.498
2005 Bremner JD, Mletzko T, Welter S, Quinn S, Williams C, Brummer M, Siddiq S, Reed L, Heim CM, Nemeroff CB. Effects of phenytoin on memory, cognition and brain structure in post-traumatic stress disorder: a pilot study. Journal of Psychopharmacology (Oxford, England). 19: 159-65. PMID 15728437 DOI: 10.1177/0269881105048996  0.512
2005 Garlow SJ, Boone E, Li W, Owens MJ, Nemeroff CB. Genetic analysis of the hypothalamic corticotropin-releasing factor system. Endocrinology. 146: 2362-8. PMID 15705776 DOI: 10.1210/en.2004-1450  0.603
2005 Sánchez MM, Noble PM, Lyon CK, Plotsky PM, Davis M, Nemeroff CB, Winslow JT. Alterations in diurnal cortisol rhythm and acoustic startle response in nonhuman primates with adverse rearing. Biological Psychiatry. 57: 373-81. PMID 15705353 DOI: 10.1016/J.Biopsych.2004.11.032  0.316
2005 Raison CL, Borisov AS, Broadwell SD, Capuron L, Woolwine BJ, Jacobson IM, Nemeroff CB, Miller AH. Depression during pegylated interferon-alpha plus ribavirin therapy: prevalence and prediction. The Journal of Clinical Psychiatry. 66: 41-8. PMID 15669887 DOI: 10.4088/JCP.V66N0106  0.321
2005 Rush AJ, Trivedi MH, Carmody TJ, Ibrahim HM, Markowitz JC, Keitner GI, Kornstein SG, Arnow B, Klein DN, Manber R, Dunner DL, Gelenberg AJ, Kocsis JH, Nemeroff CB, Fawcett J, et al. Self-reported depressive symptom measures: sensitivity to detecting change in a randomized, controlled trial of chronically depressed, nonpsychotic outpatients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 405-16. PMID 15578008 DOI: 10.1038/Sj.Npp.1300614  0.313
2005 Musselman DL, Evans DL, Nemeroff C. Erratum: The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment (Archives of General Psychiatry (1998) vol. 55 (580-592)) Australian and New Zealand Journal of Psychiatry. 39. DOI: 10.1111/J.1440-1614.2005.20050824.X  0.695
2005 Nemeroff CB, Heim CM, Thase ME, Klein DN, Rush AJ, Schatzberg AF, Ninan PT, McCullough JP, Weiss PM, Dunner DL, Rothbaum BO, Kornstein S, Keitner G, Keller MB. Erratum: Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma (Proceedings of the National Academy of Sciences of the United States of America (November 25, 2003) 100, 24 (14293-14296)) Proceedings of the National Academy of Sciences of the United States of America. 102. DOI: 10.1073/Pnas.0508675102  0.301
2005 Pace TW, Mletzko TM, Alagbe O, Vogt GJ, Hu F, Miller AH, Bruce EC, Musselman DL, Nemeroff CB, Heim CM. #107 Indicators of innate immune system activity in humans increase with psychosocial stressor challenge: Major depressives vs. non-depressives Brain, Behavior, and Immunity. 19: e56. DOI: 10.1016/j.bbi.2005.10.114  0.708
2004 Douglas Bremner J, Mletzko T, Welter S, Siddiq S, Reed L, Williams C, Heim CM, Nemeroff CB. Treatment of posttraumatic stress disorder with phenytoin: an open-label pilot study. The Journal of Clinical Psychiatry. 65: 1559-64. PMID 15554773 DOI: 10.4088/JCP.v65n1120  0.532
2004 Skelton KH, Nemeroff CB, Owens MJ. Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9303-12. PMID 15496666 DOI: 10.1523/JNEUROSCI.1737-04.2004  0.814
2004 Tyrka AR, Carpenter LL, McDougle CJ, Kirwin PD, Owens MJ, Nemeroff CB, Strong DR, Price LH. Increased cerebrospinal fluid corticotropin-releasing factor concentrations during tryptophan depletion in healthy adults. Biological Psychiatry. 56: 531-4. PMID 15450791 DOI: 10.1016/J.Biopsych.2004.06.035  0.672
2004 Newport DJ, Owens MJ, Knight DL, Ragan K, Morgan N, Nemeroff CB, Stowe ZN. Alterations in platelet serotonin transporter binding in women with postpartum onset major depression. Journal of Psychiatric Research. 38: 467-73. PMID 15380396 DOI: 10.1016/j.jpsychires.2004.01.011  0.79
2004 Grunze H, Kasper S, Goodwin G, Bowden C, Möller HJ, Akiskal H, Allain H, Ayuso-Gutiérrez J, Baldwin D, Bech P, Benkert O, Berk M, Bitter I, Bourgeois M, Burrows G, ... ... Nemeroff C, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders, part III: Maintenance treatment World Journal of Biological Psychiatry. 5: 120-135. PMID 15346536 DOI: 10.1080/15622970410029924  0.545
2004 Yoshida K, Takahashi H, Higuchi H, Kamata M, Ito K, Sato K, Naito S, Shimizu T, Itoh K, Inoue K, Suzuki T, Nemeroff CB. Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms. The American Journal of Psychiatry. 161: 1575-80. PMID 15337646 DOI: 10.1176/appi.ajp.161.9.1575  0.32
2004 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2200-7. PMID 15328528 DOI: 10.1038/sj.npp.1300546  0.788
2004 McConathy J, Owens MJ, Kilts CD, Malveaux EJ, Camp VM, Votaw JR, Nemeroff CB, Goodman MM. Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter. Nuclear Medicine and Biology. 31: 705-18. PMID 15246361 DOI: 10.1016/j.nucmedbio.2003.05.001  0.715
2004 Nemeroff CB, Owens MJ. Pharmacologic differences among the SSRIs: focus on monoamine transporters and the HPA axis. Cns Spectrums. 9: 23-31. PMID 15181382 DOI: 10.1017/S1092852900025475  0.681
2004 Arborelius L, Hawks BW, Owens MJ, Plotsky PM, Nemeroff CB. Increased responsiveness of presumed 5-HT cells to citalopram in adult rats subjected to prolonged maternal separation relative to brief separation. Psychopharmacology. 176: 248-55. PMID 15173929 DOI: 10.1007/S00213-004-1883-X  0.797
2004 Frick B, Capuron L, Schröcksnadel K, Musselman DL, Lawson DH, Nemeroff CB, Miller AH, Fuchs D. Plasma homocysteine and immune activation in patients with malignant melanoma undergoing treatment with IFN-alpha. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 311-7. PMID 15153315 DOI: 10.1089/107999004323065101  0.601
2004 Heim C, Plotsky PM, Nemeroff CB. Importance of studying the contributions of early adverse experience to neurobiological findings in depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 641-8. PMID 15034558 DOI: 10.1038/sj.npp.1300397  0.539
2004 Kinkead B, Nemeroff CB. Neurotensin, schizophrenia, and antipsychotic drug action. International Review of Neurobiology. 59: 327-49. PMID 15006494 DOI: 10.1016/S0074-7742(04)59013-X  0.643
2004 Ladd CO, Huot RL, Thrivikraman KV, Nemeroff CB, Plotsky PM. Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation. Biological Psychiatry. 55: 367-75. PMID 14960289 DOI: 10.1016/J.Biopsych.2003.10.007  0.785
2004 Vaishnavi SN, Nemeroff CB, Plott SJ, Rao SG, Kranzler J, Owens MJ. Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity. Biological Psychiatry. 55: 320-2. PMID 14744476 DOI: 10.1016/j.biopsych.2003.07.006  0.631
2004 Newport DJ, Heim C, Bonsall R, Miller AH, Nemeroff CB. Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Biological Psychiatry. 55: 10-20. PMID 14706420 DOI: 10.1016/S0006-3223(03)00692-9  0.701
2004 Carpenter LL, Tyrka AR, McDougle CJ, Malison RT, Owens MJ, Nemeroff CB, Price LH. Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 777-84. PMID 14702025 DOI: 10.1038/Sj.Npp.1300375  0.685
2004 Pomara N, Willoughby LM, Ritchie JC, Sidtis JJ, Greenblatt DJ, Nemeroff CB. Interdose elevation in plasma cortisol during chronic treatment with alprazolam but not lorazepam in the elderly. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 605-11. PMID 14694352 DOI: 10.1038/sj.npp.1300365  0.541
2004 Nemeroff CB, Radford MH, Golden RN. Introduction Advances in the Treatment of Mood and Anxiety Disorders Cns Spectrums. 9: 5-5. DOI: 10.1017/S109285290002544X  0.522
2003 Owens MJ, Nemeroff CB. Pharmacology of valproate. Psychopharmacology Bulletin. 37: 17-24. PMID 14624230  0.604
2003 Nemeroff CB, Heim CM, Thase ME, Klein DN, Rush AJ, Schatzberg AF, Ninan PT, McCullough JP, Weiss PM, Dunner DL, Rothbaum BO, Kornstein S, Keitner G, Keller MB. Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proceedings of the National Academy of Sciences of the United States of America. 100: 14293-6. PMID 14615578 DOI: 10.1073/Pnas.2336126100  0.552
2003 Capuron L, Neurauter G, Musselman DL, Lawson DH, Nemeroff CB, Fuchs D, Miller AH. Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment. Biological Psychiatry. 54: 906-14. PMID 14573318 DOI: 10.1016/S0006-3223(03)00173-2  0.635
2003 Nemeroff CB, Owens MJ. Neuropharmacology of paroxetine. Psychopharmacology Bulletin. 37: 8-18. PMID 14566196  0.624
2003 Gutman DA, Nemeroff CB. Persistent central nervous system effects of an adverse early environment: clinical and preclinical studies. Physiology & Behavior. 79: 471-8. PMID 12954441 DOI: 10.1016/S0031-9384(03)00166-5  0.582
2003 Serebruany VL, Glassman AH, Malinin AI, Nemeroff CB, Musselman DL, van Zyl LT, Finkel MS, Krishnan KR, Gaffney M, Harrison W, Califf RM, O'Connor CM. Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy. Circulation. 108: 939-44. PMID 12912814 DOI: 10.1161/01.CIR.0000085163.21752.0A  0.637
2003 Capuron L, Raison CL, Musselman DL, Lawson DH, Nemeroff CB, Miller AH. Association of exaggerated HPA axis response to the initial injection of interferon-alpha with development of depression during interferon-alpha therapy. The American Journal of Psychiatry. 160: 1342-5. PMID 12832253 DOI: 10.1176/appi.ajp.160.7.1342  0.626
2003 Gyulai L, Bowden CL, McElroy SL, Calabrese JR, Petty F, Swann AC, Chou JC, Wassef A, Risch CS, Hirschfeld RM, Nemeroff CB, Keck PE, Evans DL, Wozniak PJ. Maintenance efficacy of divalproex in the prevention of bipolar depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1374-82. PMID 12784116 DOI: 10.1038/sj.npp.1300190  0.535
2003 Cáceda R, Kinkead B, Nemeroff CB. Do neurotensin receptor agonists represent a novel class of antipsychotic drugs? Seminars in Clinical Neuropsychiatry. 8: 94-108. PMID 12728409 DOI: 10.1053/scnp.2003.50009  0.771
2003 Penza KM, Heim C, Nemeroff CB. Neurobiological effects of childhood abuse: implications for the pathophysiology of depression and anxiety. Archives of Women's Mental Health. 6: 15-22. PMID 12715261 DOI: 10.1007/s00737-002-0159-x  0.8
2003 Newport DJ, Heim C, Owens MJ, Ritchie JC, Ramsey CH, Bonsall R, Miller AH, Nemeroff CB. Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 569-76. PMID 12629539 DOI: 10.1038/sj.npp.1300071  0.811
2003 Goodman MM, Chen P, Plisson C, Martarello L, Galt J, Votaw JR, Kilts CD, Malveaux G, Camp VM, Shi B, Ely TD, Howell L, McConathy J, Nemeroff CB. Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography. Journal of Medicinal Chemistry. 46: 925-35. PMID 12620070 DOI: 10.1021/Jm0100180  0.573
2003 Gilmor ML, Skelton KH, Nemeroff CB, Owens MJ. The effects of chronic treatment with the mood stabilizers valproic acid and lithium on corticotropin-releasing factor neuronal systems. The Journal of Pharmacology and Experimental Therapeutics. 305: 434-9. PMID 12606697 DOI: 10.1124/jpet.102.045419  0.809
2003 Stowe ZN, Hostetter AL, Owens MJ, Ritchie JC, Sternberg K, Cohen LS, Nemeroff CB. The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations. The Journal of Clinical Psychiatry. 64: 73-80. PMID 12590627 DOI: 10.4088/Jcp.V64N0114  0.753
2003 Gutman DA, Owens MJ, Skelton KH, Thrivikraman KV, Nemeroff CB. The corticotropin-releasing factor1 receptor antagonist R121919 attenuates the behavioral and endocrine responses to stress. The Journal of Pharmacology and Experimental Therapeutics. 304: 874-80. PMID 12538845 DOI: 10.1124/jpet.102.042788  0.805
2003 Ritchie JC, Davis TP, Nemeroff CB. Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 22-33. PMID 12496937 DOI: 10.1038/sj.npp.1300014  0.508
2003 Heim C, Meinlschmidt G, Nemeroff CB. Neurobiology of Early-Life Stress Psychiatric Annals. 33: 18-26. DOI: 10.3928/0048-5713-20030101-05  0.481
2003 KINKEAD B, NEMEROFF CB. Handbook of Physiology: A Critical, Comprehensive Presentation of Physiological Knowledge and Concepts, Section 7: The Endocrine System, vol. IV: Coping With the Environment: Neural and Endocrine Mechanisms American Journal of Psychiatry. 160: 602-603. DOI: 10.1176/appi.ajp.160.3.602  0.599
2003 Nemeroff CB, Owens MJ. Reply to 'Editorial policies on financial disclosure' Nature Neuroscience. 6: 1000-1001. DOI: 10.1038/NN1003-1000  0.595
2003 Watkins L, Davidson J, Connor K, Beebe K, Krulewicz S, Abraham K, Zhang W, Owens M, Nemeroff C. P.1.233 Effects of paroxetine and venlafaxine-XP on heart rate variability in depression European Neuropsychopharmacology. 13: S274. DOI: 10.1016/S0924-977X(03)91943-2  0.635
2003 Fitzgerald LZ, Chang L, Lee CK, Owens MJ, Mayer M, Naliboff BD, Nemeroff CB, Mayer EA. Elevated levels of central stress mediators in irritable bowel syndrome Gastroenterology. 124: A252. DOI: 10.1016/S0016-5085(03)81266-0  0.623
2002 Nemeroff CB, Kinkead B, Goldstein J. Quetiapine: preclinical studies, pharmacokinetics, drug interactions, and dosing. The Journal of Clinical Psychiatry. 63: 5-11. PMID 12562141  0.621
2002 Vythilingam M, Heim C, Newport J, Miller AH, Anderson E, Bronen R, Brummer M, Staib L, Vermetten E, Charney DS, Nemeroff CB, Bremner JD. Childhood trauma associated with smaller hippocampal volume in women with major depression. The American Journal of Psychiatry. 159: 2072-80. PMID 12450959 DOI: 10.1176/Appi.Ajp.159.12.2072  0.544
2002 Nemeroff CB, Owens MJ. Treatment of mood disorders. Nature Neuroscience. 5: 1068-70. PMID 12403988 DOI: 10.1038/nn943  0.648
2002 Hirschfeld RM, Montgomery SA, Aguglia E, Amore M, Delgado PL, Gastpar M, Hawley C, Kasper S, Linden M, Massana J, Mendlewicz J, Möller HJ, Nemeroff CB, Saiz J, Such P, et al. Partial response and nonresponse to antidepressant therapy: current approaches and treatment options. The Journal of Clinical Psychiatry. 63: 826-37. PMID 12363125 DOI: 10.4088/Jcp.V63N0913  0.31
2002 Gilmor ML, Owens MJ, Nemeroff CB. Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine. The American Journal of Psychiatry. 159: 1702-10. PMID 12359676 DOI: 10.1176/appi.ajp.159.10.1702  0.799
2002 Mathew SJ, Coplan JD, Smith EL, Scharf BA, Owens MJ, Nemeroff CB, Mann JJ, Gorman JM, Rosenblum LA. Cerebrospinal fluid concentrations of biogenic amines and corticotropin-releasing factor in adolescent non-human primates as a function of the timing of adverse early rearing. Stress (Amsterdam, Netherlands). 5: 185-93. PMID 12186681 DOI: 10.1080/1025389021000010521  0.657
2002 Newport DJ, Stowe ZN, Nemeroff CB. Parental depression: animal models of an adverse life event. The American Journal of Psychiatry. 159: 1265-83. PMID 12153816 DOI: 10.1176/appi.ajp.159.8.1265  0.709
2002 Golden RN, Nemeroff CB, McSorley P, Pitts CD, Dubé EM. Efficacy and tolerability of controlled-release and immediate-release paroxetine in the treatment of depression. The Journal of Clinical Psychiatry. 63: 577-84. PMID 12143913 DOI: 10.4088/Jcp.V63N0707  0.525
2002 Rosenblum LA, Smith EL, Altemus M, Scharf BA, Owens MJ, Nemeroff CB, Gorman JM, Coplan JD. Differing concentrations of corticotropin-releasing factor and oxytocin in the cerebrospinal fluid of bonnet and pigtail macaques. Psychoneuroendocrinology. 27: 651-60. PMID 12084658 DOI: 10.1016/S0306-4530(01)00056-7  0.652
2002 Binder EB, Gross RE, Nemeroff CB, Kilts CD. Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology. 161: 288-95. PMID 12021832 DOI: 10.1007/s00213-002-1031-4  0.512
2002 Heim C, Newport DJ, Wagner D, Wilcox MM, Miller AH, Nemeroff CB. The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: a multiple regression analysis. Depression and Anxiety. 15: 117-25. PMID 12001180 DOI: 10.1002/da.10015  0.674
2002 Musselman DL, Marzec U, Davidoff M, Manatunga AK, Gao F, Reemsnyder A, Duggirala S, Larsen H, Taylor RW, Hanson S, Nemeroff CB. Platelet activation and secretion in patients with major depression, thoracic aortic atherosclerosis, or renal dialysis treatment. Depression and Anxiety. 15: 91-101. PMID 12001177 DOI: 10.1002/Da.10020  0.644
2002 Heim C, Nemeroff CB. Neurobiology of early life stress: clinical studies. Seminars in Clinical Neuropsychiatry. 7: 147-59. PMID 11953939 DOI: 10.1053/Scnp.2002.33127  0.526
2002 Gutman DA, Nemeroff CB. Neurobiology of early life stress: rodent studies. Seminars in Clinical Neuropsychiatry. 7: 89-95. PMID 11953932 DOI: 10.1053/Scnp.2002.31781  0.535
2002 Davidson JRT, Gadde KM, Fairbank JA, Ranga Rama Krishnan K, Califf RM, Binanay C, Parker CB, Pugh N, Hartwell TD, Vitiello B, Ritz L, Severe J, Cole JO, De Battista C, Murali Doraiswamy P, ... ... Nemeroff CB, et al. Effect of Hypericum perforatum (St John's wort) in major depressive disorder: A randomized controlled trial Journal of the American Medical Association. 287: 1807-1814. PMID 11939866 DOI: 10.1001/JAMA.287.14.1807  0.323
2002 Capuron L, Gumnick JF, Musselman DL, Lawson DH, Reemsnyder A, Nemeroff CB, Miller AH. Neurobehavioral effects of interferon-alpha in cancer patients: phenomenology and paroxetine responsiveness of symptom dimensions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 643-52. PMID 11927189 DOI: 10.1016/S0893-133X(01)00407-9  0.627
2002 Charney DS, Nemeroff CB, Lewis L, Laden SK, Gorman JM, Laska EM, Borenstein M, Bowden CL, Caplan A, Emslie GJ, Evans DL, Geller B, Grabowski LE, Herson J, Kalin NH, et al. National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Archives of General Psychiatry. 59: 262-70. PMID 11879164 DOI: 10.1001/Archpsyc.59.3.262  0.526
2002 Stout SC, Owens MJ, Nemeroff CB. Regulation of corticotropin-releasing factor neuronal systems and hypothalamic-pituitary-adrenal axis activity by stress and chronic antidepressant treatment. The Journal of Pharmacology and Experimental Therapeutics. 300: 1085-92. PMID 11861819 DOI: 10.1124/Jpet.300.3.1085  0.813
2002 Hirschfeld RM, Dunner DL, Keitner G, Klein DN, Koran LM, Kornstein SG, Markowitz JC, Miller I, Nemeroff CB, Ninan PT, Rush AJ, Schatzberg AF, Thase ME, Trivedi MH, Borian FE, et al. Does psychosocial functioning improve independent of depressive symptoms? A comparison of nefazodone, psychotherapy, and their combination. Biological Psychiatry. 51: 123-33. PMID 11822991 DOI: 10.1016/S0006-3223(01)01291-4  0.335
2002 Kinkead B, Nemeroff CB. Neurotensin: an endogenous antipsychotic? Current Opinion in Pharmacology. 2: 99-103. PMID 11786316 DOI: 10.1016/S1471-4892(01)00128-X  0.627
2002 HEIM C, NEWPORT DJ, MILLER AH, NEMEROFF CB. Dr. Heim and Colleagues Reply American Journal of Psychiatry. 159: 157-b-158. DOI: 10.1176/appi.ajp.159.1.157-b  0.442
2002 Evans D, Nemeroff C, Thase M, Wan G, Panish J, Cantillon M. Improvement in social activity level, general life and cognitive functioning with venlafaxine versus fluoxetine in inpatients with melancholic depression European Psychiatry. 17: 194. DOI: 10.1016/S0924-9338(02)80830-6  0.486
2002 Kalin N, Nemeroff C, Wan G, Panish J, Cantillon M. Improvement in general life functioning with venlafaxine versus fluoxetine in outpatients with major depression European Psychiatry. 17: 194. DOI: 10.1016/S0924-9338(02)80829-X  0.307
2001 Ressler KJ, Nemeroff CB. Role of norepinephrine in the pathophysiology of neuropsychiatric disorders. Cns Spectrums. 6: 663-6, 670. PMID 15520614 DOI: 10.1017/S1092852900001358  0.315
2001 Owens MJ, Nemeroff CB. An old transmitter in a new millennium. Cns Spectrums. 6: 655. PMID 15520612 DOI: 10.1017/S1092852900001334  0.587
2001 O'Brien D, Skelton KH, Owens MJ, Nemeroff CB. Are CRF receptor antagonists potential antidepressants? Human Psychopharmacology. 16: 81-87. PMID 12404602 DOI: 10.1002/hup.187  0.823
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biological Psychiatry. 50: 856-72. PMID 11743941 DOI: 10.1016/S0006-3223(01)01211-2  0.785
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin and dopamine interactions. Pharmacological Reviews. 53: 453-86. PMID 11734615  0.772
2001 Sharma RP, Martis B, Rosen C, Jonalagadda J, Nemeroff CB, Bissette G. CSF thyrotropin-releasing hormone concentrations differ in patients with schizoaffective disorder from patients with schizophrenia or mood disorders. Journal of Psychiatric Research. 35: 287-91. PMID 11591431 DOI: 10.1016/S0022-3956(01)00033-4  0.726
2001 Owens MJ, Knight DL, Nemeroff CB. Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine. Biological Psychiatry. 50: 345-50. PMID 11543737 DOI: 10.1016/S0006-3223(01)01145-3  0.633
2001 Coplan JD, Smith EL, Altemus M, Scharf BA, Owens MJ, Nemeroff CB, Gorman JM, Rosenblum LA. Variable foraging demand rearing: sustained elevations in cisternal cerebrospinal fluid corticotropin-releasing factor concentrations in adult primates. Biological Psychiatry. 50: 200-4. PMID 11513819 DOI: 10.1016/S0006-3223(01)01175-1  0.646
2001 Musselman DL, Miller AH, Porter MR, Manatunga A, Gao F, Penna S, Pearce BD, Landry J, Glover S, McDaniel JS, Nemeroff CB. Higher than normal plasma interleukin-6 concentrations in cancer patients with depression: preliminary findings. The American Journal of Psychiatry. 158: 1252-7. PMID 11481159 DOI: 10.1176/Appi.Ajp.158.8.1252  0.642
2001 Heim C, Nemeroff CB. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biological Psychiatry. 49: 1023-39. PMID 11430844 DOI: 10.1016/S0006-3223(01)01157-X  0.553
2001 Nemeroff CB, Evans DL, Gyulai L, Sachs GS, Bowden CL, Gergel IP, Oakes R, Pitts CD. Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression. The American Journal of Psychiatry. 158: 906-12. PMID 11384898 DOI: 10.1176/appi.ajp.158.6.906  0.53
2001 Stout SC, Owens MJ, Lindsey KP, Knight DL, Nemeroff CB. Effects of sodium valproate on corticotropin-releasing factor systems in rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 624-31. PMID 11331142 DOI: 10.1016/S0893-133X(00)00243-8  0.812
2001 Martarello L, Kilts CD, Ely T, Owens MJ, Nemeroff CB, Camp M, Goodman MM. Synthesis and characterization of fluorinated and iodinated pyrrolopyrimidines as PET/SPECT ligands for the CRF1 receptor. Nuclear Medicine and Biology. 28: 187-95. PMID 11295429 DOI: 10.1016/S0969-8051(00)00199-2  0.622
2001 Heim C, Newport DJ, Bonsall R, Miller AH, Nemeroff CB. Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse. The American Journal of Psychiatry. 158: 575-81. PMID 11282691 DOI: 10.1176/appi.ajp.158.4.575  0.718
2001 Musselman DL, Lawson DH, Gumnick JF, Manatunga AK, Penna S, Goodkin RS, Greiner K, Nemeroff CB, Miller AH. Paroxetine for the prevention of depression induced by high-dose interferon alfa. The New England Journal of Medicine. 344: 961-6. PMID 11274622 DOI: 10.1056/Nejm200103293441303  0.648
2001 Stout SC, Owens MJ, Nemeroff CB. Neurokinin(1) receptor antagonists as potential antidepressants. Annual Review of Pharmacology and Toxicology. 41: 877-906. PMID 11264480 DOI: 10.1146/Annurev.Pharmtox.41.1.877  0.79
2001 Binder EB, Kinkead B, Owens MJ, Kilts CD, Nemeroff CB. Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 601-8. PMID 11160439 DOI: 10.1523/Jneurosci.21-02-00601.2001  0.788
2001 Radke JM, Owens MJ, Nemeroff CB. The effects of glutamate receptor agonists on neurotensin release using in vivo microdialysis. European Journal of Pharmacology. 411: 129-134. PMID 11137867 DOI: 10.1016/S0014-2999(00)00912-2  0.647
2001 Wisner KL, Findling RL, Perel JM, Stowe ZN, Cohen LS, Ritchie JC, Owens MJ, Nemeroff CB. Paroxetine in breast milk [3] (multiple letters) American Journal of Psychiatry. 158: 144-145. PMID 11136654 DOI: 10.1176/appi.ajp.158.1.144  0.726
2001 STOWE ZN, COHEN LS, RITCHIE JC, OWENS MJ, NEMEROFF CB. Dr. Stowe and Colleagues Reply American Journal of Psychiatry. 158: 144-b-145. DOI: 10.1176/APPI.AJP.158.1.144-B  0.731
2000 Montgomery SA, Schatzberg AF, Guelfi JD, Kasper S, Nemeroff C, Swann A, Zajecka J. Pharmacotherapy of depression and mixed states in bipolar disorder. Journal of Affective Disorders. 59: S39-S56. PMID 11121826 DOI: 10.1016/S0165-0327(00)00178-6  0.352
2000 Kinkead B, Owens MJ, Nemeroff CB. The effects of acute antipsychotic drug administration on the neurotensin system of the developing rat brain. Brain Research. Developmental Brain Research. 124: 1-10. PMID 11113506 DOI: 10.1016/S0165-3806(00)00097-3  0.765
2000 Vythilingam M, Anderson GM, Owens MJ, Halaszynski TM, Bremner JD, Carpenter LL, Heninger GR, Nemeroff CB, Charney DS. Cerebrospinal fluid corticotropin-releasing hormone in healthy humans: effects of yohimbine and naloxone. The Journal of Clinical Endocrinology and Metabolism. 85: 4138-45. PMID 11095445 DOI: 10.1210/jcem.85.11.6968  0.67
2000 Heim C, Newport DJ, Miller AH, Nemeroff CB. Long-term neuroendocrine effects of childhood maltreatment Jama. 284: 2321. PMID 11066180  0.614
2000 Kaufman J, Plotsky PM, Nemeroff CB, Charney DS. Effects of early adverse experiences on brain structure and function: clinical implications. Biological Psychiatry. 48: 778-90. PMID 11063974 DOI: 10.1016/S0006-3223(00)00998-7  0.394
2000 Skelton KH, Owens MJ, Nemeroff CB. The neurobiology of urocortin. Regulatory Peptides. 93: 85-92. PMID 11033056 DOI: 10.1016/S0167-0115(00)00180-4  0.795
2000 Nemeroff CB, Musselman DL. Are platelets the link between depression and ischemic heart disease? American Heart Journal. 140: 57-62. PMID 11011349 DOI: 10.1067/Mhj.2000.109978  0.624
2000 Bouwer C, Claassen J, Dinan TG, Nemeroff CB. Prednisone augmentation in treatment-resistant depression with fatigue and hypocortisolaemia: a case series. Depression and Anxiety. 12: 44-50. PMID 10999245 DOI: 10.1002/1520-6394(2000)12:1<44::AID-DA6>3.0.CO;2-C  0.352
2000 Kinkead B, Lorch SM, Owens MJ, Nemeroff CB. Sex- and estrous cycle-related differences in the effects of acute antipsychotic drug administration on neurotensin-containing neurons in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 295: 205-11. PMID 10991980  0.747
2000 Kinkead B, Shahid S, Owens MJ, Nemeroff CB. Effects of acute and subchronic administration of typical and atypical antipsychotic drugs on the neurotensin system of the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 295: 67-73. PMID 10991962  0.757
2000 Musselman DL, Marzec UM, Manatunga A, Penna S, Reemsnyder A, Knight BT, Baron A, Hanson SR, Nemeroff CB. Platelet reactivity in depressed patients treated with paroxetine: preliminary findings. Archives of General Psychiatry. 57: 875-82. PMID 10986551 DOI: 10.1001/Archpsyc.57.9.875  0.66
2000 Coplan JD, Smith EL, Trost RC, Scharf BA, Altemus M, Bjornson L, Owens MJ, Gorman JM, Nemeroff CB, Rosenblum LA. Growth hormone response to clonidine in adversely reared young adult primates: relationship to serial cerebrospinal fluid corticotropin-releasing factor concentrations. Psychiatry Research. 95: 93-102. PMID 10963795 DOI: 10.1016/S0165-1781(00)00173-6  0.672
2000 Skelton KH, Nemeroff CB, Owens MJ. A comparison of plasma alprazolam concentrations following different routes of chronic administration in the Sprague-Dawley rat: implications for psychotropic drug research. Psychopharmacology. 151: 72-6. PMID 10958119 DOI: 10.1007/s002130000469  0.792
2000 Heim C, Newport DJ, Heit S, Graham YP, Wilcox M, Bonsall R, Miller AH, Nemeroff CB. Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. Jama. 284: 592-7. PMID 10918705 DOI: 10.1001/Jama.284.5.592  0.715
2000 Stout SC, Mortas P, Owens MJ, Nemeroff CB, Moreau J. Increased corticotropin-releasing factor concentrations in the bed nucleus of the stria terminalis of anhedonic rats. European Journal of Pharmacology. 401: 39-46. PMID 10915835 DOI: 10.1016/S0014-2999(00)00412-X  0.822
2000 Keller MB, McCullough JP, Klein DN, Arnow B, Dunner DL, Gelenberg AJ, Markowitz JC, Nemeroff CB, Russell JM, Thase ME, Trivedi MH, Zajecka J. A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. The New England Journal of Medicine. 342: 1462-70. PMID 10816183 DOI: 10.1056/Nejm200005183422001  0.325
2000 Owens MJ, Knight DL, Nemeroff CB. Paroxetine binding to the rat norepinephrine transporter in vivo. Biological Psychiatry. 47: 842-5. PMID 10812044 DOI: 10.1016/S0006-3223(99)00314-5  0.65
2000 Newport DJ, Nemeroff CB. Neurobiology of posttraumatic stress disorder. Current Opinion in Neurobiology. 10: 211-8. PMID 10753802 DOI: 10.1016/S0959-4388(00)00080-5  0.627
2000 Ladd CO, Huot RL, Thrivikraman KV, Nemeroff CB, Meaney MJ, Plotsky PM. Long-term behavioral and neuroendocrine adaptations to adverse early experience. Progress in Brain Research. 122: 81-103. PMID 10737052 DOI: 10.1016/S0079-6123(08)62132-9  0.757
2000 Musselman DL, Nemeroff CB. Depression really does hurt your heart: stress, depression, and cardiovascular disease. Progress in Brain Research. 122: 43-59. PMID 10737050 DOI: 10.1016/S0079-6123(08)62130-5  0.647
2000 Stowe ZN, Cohen LS, Hostetter A, Ritchie JC, Owens MJ, Nemeroff CB. Paroxetine in human breast milk and nursing infants. The American Journal of Psychiatry. 157: 185-9. PMID 10671385 DOI: 10.1176/appi.ajp.157.2.185  0.744
2000 Skelton KH, Nemeroff CB, Knight DL, Owens MJ. Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1240-8. PMID 10648728 DOI: 10.1523/Jneurosci.20-03-01240.2000  0.806
2000 Gutman D, Owens M, Nemeroff C. Corticotropin-releasing factor antagonists as novel psychotherapeutics Drugs of the Future. 25: 923. DOI: 10.1358/DOF.2000.025.09.665577  0.712
2000 Heim C, Newport DJ, Graham Y, Heit S, Bonsall R, Miller AH, Nemeroff CB. Pituitary-adrenal responsiveness of adult survivors of childhood abuse in the CRF stimulation test Psychoneuroendocrinology. 25. DOI: 10.1016/S0306-4530(00)90141-0  0.497
2000 Martarello L, Kilts CD, Ely T, Owens MJ, Nemeroff CB, Goodman MM. Design, synthesis and evaluation of amino-anilino-pyramidines as potential spect ligands for the CRF1 receptor Psychoneuroendocrinology. 25: S37. DOI: 10.1016/S0306-4530(00)90130-6  0.609
2000 Skelton KH, Nemeroff CB, Owens MJ. Urocortin, the CRF2 receptor and effects of anxiolytic drugs Psychoneuroendocrinology. 25: S17. DOI: 10.1016/S0306-4530(00)90091-X  0.807
2000 Musselman DL, Ninan PT, Knight BT, Nemeroff CB. Hypothalamic-pituitary-thyroid axis abnormalities, major depression, and treatment response Psychoneuroendocrinology. 25: S11. DOI: 10.1016/S0306-4530(00)90080-5  0.651
2000 Mussleman D, Marzec U, Owens M, Reemsnyder A, Goodkin R, Hanson S, Nemeroff C. 253. Platelet activation in treatment responders vs. nonresponders in patients with major depression Biological Psychiatry. 47: S77. DOI: 10.1016/S0006-3223(00)00517-5  0.651
2000 Musselman D, Marzec U, Davidoff M, Reemsnyder A, Goodkin R, Hanson S, Harker L, Taylor W, Nemeroff C. 252. Platelet activation of depressed patients in comparison to patients with aortic atherosclerosis Biological Psychiatry. 47: S76-S77. DOI: 10.1016/S0006-3223(00)00516-3  0.626
2000 Nemeroff C, Owens M, Skelton K, Guttman D, Winslow J, Plotsky P. 210. CRF1 receptor antagonists as novel putative antidepressants and anxiolytics Biological Psychiatry. 47: S64. DOI: 10.1016/S0006-3223(00)00473-X  0.787
1999 Owens MJ, Nemeroff CB. Corticotropin-releasing factor antagonists in affective disorders. Expert Opinion On Investigational Drugs. 8: 1849-1858. PMID 11139829 DOI: 10.1517/13543784.8.11.1849  0.679
1999 Heim C, Nemeroff CB. The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders. Biological Psychiatry. 46: 1509-22. PMID 10599479 DOI: 10.1016/S0006-3223(99)00224-3  0.568
1999 Ressler KJ, Nemeroff CB. Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biological Psychiatry. 46: 1219-33. PMID 10560027 DOI: 10.1016/S0006-3223(99)00127-4  0.377
1999 Graham YP, Heim C, Goodman SH, Miller AH, Nemeroff CB. The effects of neonatal stress on brain development: implications for psychopathology. Development and Psychopathology. 11: 545-65. PMID 10532624 DOI: 10.1017/S0954579499002205  0.571
1999 Kinkead B, Binder EB, Nemeroff CB. Does neurotensin mediate the effects of antipsychotic drugs? Biological Psychiatry. 46: 340-51. PMID 10435199 DOI: 10.1016/S0006-3223(99)00070-0  0.708
1999 Ehlers CL, Somes C, Li TK, Lumeng L, Kinkead B, Owens MJ, Nemeroff CB. Neurontensin studies in alcohol naive, preferring and non-preferring rats. Neuroscience. 93: 227-36. PMID 10430486 DOI: 10.1016/S0306-4522(99)00113-X  0.754
1999 Musselman DL, McDaniel JS, Porter MR, Nemeroff CB. Screening for depression. Journal of the Medical Association of Georgia. 88: 47-53. PMID 10087715  0.588
1999 Arborelius L, Owens MJ, Plotsky PM, Nemeroff CB. The role of corticotropin-releasing factor in depression and anxiety disorders. The Journal of Endocrinology. 160: 1-12. PMID 9854171 DOI: 10.1677/joe.0.1600001  0.827
1999 Owens MJ, Nemeroff CB. Corticotropin-Releasing Factor Antagonists Cns Drugs. 12: 85-92. DOI: 10.2165/00023210-199912020-00001  0.678
1998 Bissette G, Cook L, Smith W, Dole KC, Crain B, Nemeroff CB. Regional Neuropeptide Pathology in Alzheimer's Disease: Corticotropin-Releasing Factor and Somatostatin. Journal of Alzheimer's Disease : Jad. 1: 91-105. PMID 12214006 DOI: 10.3233/Jad-1998-1203  0.694
1998 Malison RT, Price LH, Berman R, van Dyck CH, Pelton GH, Carpenter L, Sanacora G, Owens MJ, Nemeroff CB, Rajeevan N, Baldwin RM, Seibyl JP, Innis RB, Charney DS. Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biological Psychiatry. 44: 1090-8. PMID 9836013 DOI: 10.1016/S0006-3223(98)00272-8  0.656
1998 Nemeroff CB, Musselman DL, Evans DL. Depression and cardiac disease. Depression and Anxiety. 8: 71-9. PMID 9809217 DOI: 10.1002/(SICI)1520-6394(1998)8:1+<71::AID-DA11>3.0.CO;2-X  0.686
1998 Owens MJ, Nemeroff CB. The serotonin transporter and depression. Depression and Anxiety. 8: 5-12. PMID 9809208 DOI: 10.1002/(SICI)1520-6394(1998)8:1+<5::AID-DA2>3.0.CO;2-I  0.641
1998 Heuser I, Bissette G, Dettling M, Schweiger U, Gotthardt U, Schmider J, Lammers CH, Nemeroff CB, Holsboer F. Cerebrospinal fluid concentrations of corticotropin-releasing hormone, vasopressin, and somatostatin in depressed patients and healthy controls: response to amitriptyline treatment. Depression and Anxiety. 8: 71-9. PMID 9784981 DOI: 10.1002/(Sici)1520-6394(1998)8:2<71::Aid-Da5>3.0.Co;2-N  0.728
1998 Newport DJ, Nemeroff CB. Assessment and treatment of depression in the cancer patient. Journal of Psychosomatic Research. 45: 215-37. PMID 9776368 DOI: 10.1016/S0022-3999(98)00011-7  0.618
1998 Radke JM, Owens MJ, Ritchie JC, Nemeroff CB. Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions. Proceedings of the National Academy of Sciences of the United States of America. 95: 11462-4. PMID 9736759 DOI: 10.1073/pnas.95.19.11462  0.72
1998 Musselman DL, Evans DL, Nemeroff CB. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Archives of General Psychiatry. 55: 580-92. PMID 9672048 DOI: 10.1001/archpsyc.55.7.580  0.708
1998 Plotsky PM, Owens MJ, Nemeroff CB. Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. The Psychiatric Clinics of North America. 21: 293-307. PMID 9670227 DOI: 10.1016/S0193-953X(05)70006-X  0.692
1998 Mandell AJ, Owens MJ, Selz KA, Morgan WN, Shlesinger MF, Nemeroff CB. Mode matches in hydrophobic free energy eigenfunctions predict peptide-protein interactions. Biopolymers. 46: 89-101. PMID 9664843 DOI: 10.1002/(SICI)1097-0282(199808)46:2<89::AID-BIP4>3.0.CO;2-T  0.612
1998 Coplan JD, Trost RC, Owens MJ, Cooper TB, Gorman JM, Nemeroff CB, Rosenblum LA. Cerebrospinal fluid concentrations of somatostatin and biogenic amines in grown primates reared by mothers exposed to manipulated foraging conditions. Archives of General Psychiatry. 55: 473-7. PMID 9596051 DOI: 10.1001/Archpsyc.55.5.473  0.658
1998 Musselman D, Knight B, Baron A, Nemeroff C. 330. Further studies on altered platelet reactivity in major depression Biological Psychiatry. 43: S99. DOI: 10.1016/S0006-3223(98)90778-8  0.635
1998 Nemeroff C, Owens M, Plotsky P. 265. The HPA axis and the pathophysiology of depression: The role of early adverse Biological Psychiatry. 43: S79-S80. DOI: 10.1016/S0006-3223(98)90713-2  0.662
1997 Llewellyn AM, Stowe ZN, Nemeroff CB. Depression during pregnancy and the puerperium. The Journal of Clinical Psychiatry. 58: 26-32. PMID 9427874  0.515
1997 Slotkin TA, Hays JC, Nemeroff CB, Carroll BJ. Dexamethasone suppression test identifies a subset of elderly depressed patients with reduced platelet serotonin transport and resistance to imipramine inhibition of transport. Depression and Anxiety. 6: 19-25. PMID 9394871 DOI: 10.1002/(SICI)1520-6394(1997)6:1<19::AID-DA3>3.0.CO;2-0  0.342
1997 Stowe ZN, Owens MJ, Landry JC, Kilts CD, Ely T, Llewellyn A, Nemeroff CB. Sertraline and desmethylsertraline in human breast milk and nursing infants. The American Journal of Psychiatry. 154: 1255-60. PMID 9286185 DOI: 10.1176/Ajp.154.9.1255  0.7
1997 Heim C, Owens MJ, Plotsky PM, Nemeroff CB. The role of early adverse life events in the etiology of depression and posttraumatic stress disorder. Focus on corticotropin-releasing factor. Annals of the New York Academy of Sciences. 821: 194-207. PMID 9238204 DOI: 10.1111/j.1749-6632.1997.tb48279.x  0.72
1997 Heim C, Owens MJ, Plotsky PM, Nemeroff CB. Persistent changes in corticotropin-releasing factor systems due to early life stress: relationship to the pathophysiology of major depression and post-traumatic stress disorder. Psychopharmacology Bulletin. 33: 185-92. PMID 9230630  0.716
1997 Sharma RP, Janicak PG, Bissette G, Nemeroff CB. CSF neurotensin concentrations and antipsychotic treatment in schizophrenia and schizoaffective disorder. The American Journal of Psychiatry. 154: 1019-21. PMID 9210757 DOI: 10.1176/Ajp.154.7.1019  0.702
1997 Bremner JD, Licinio J, Darnell A, Krystal JH, Owens MJ, Southwick SM, Nemeroff CB, Charney DS. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. The American Journal of Psychiatry. 154: 624-9. PMID 9137116 DOI: 10.1176/Ajp.154.5.624  0.663
1997 Behan DP, Khongsaly O, Owens MJ, Chung HD, Nemeroff CB, De Souza EB. Corticotropin-releasing factor (CRF), CRF-binding protein (CRF-BP), and CRF/CRF-BP complex in Alzheimer's disease and control postmortem human brain. Journal of Neurochemistry. 68: 2053-60. PMID 9109532 DOI: 10.1046/J.1471-4159.1997.68052053.X  0.647
1997 Stowe ZN, Levy ST, Nemeroff CB. Comorbid postpartum depression and bereavement: a complicated case. The American Journal of Psychiatry. 154: 418-22. PMID 9054793 DOI: 10.1176/Ajp.154.3.418  0.569
1997 McDaniel JS, Musselman DL, Nemeroff CB. Cancer and Depression: Theory and Treatment Psychiatric Annals. 27: 360-364. DOI: 10.3928/0048-5713-19970501-12  0.618
1997 Heit S, Owens MJ, Plotsky P, Nemeroff CB. ■ REVIEW : Corticotropin-releasing Factor, Stress, and Depression The Neuroscientist. 3: 186-194. DOI: 10.1177/107385849700300312  0.695
1997 Nemeroff C, Owens M, Plotsky P. S.15.05 The HPA axis and the pathophysiology of depression: The role of early adverse experience European Neuropsychopharmacology. 7: S109. DOI: 10.1016/S0924-977X(97)88411-8  0.657
1997 Stowe ZN, Llewellyn AM, Strader JR, Landry JC, Owens MJ, Ritchie J, Kilts CD, Nemeroff CB. S.15.04 Identification and treatment of postpartum depression European Neuropsychopharmacology. 7. DOI: 10.1016/S0924-977X(97)88410-6  0.732
1996 Green JP, Newman NJ, Stowe ZN, Nemeroff CB. "Normal pressure" pseudotumor cerebri. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 16: 241-6. PMID 8956158 DOI: 10.1097/00041327-199612000-00003  0.566
1996 Adinoff B, Anton R, Linnoila M, Guidotti A, Nemeroff CB, Bissette G. Cerebrospinal fluid concentrations of corticotropin-releasing hormone (CRH) and diazepam-binding inhibitor (DBI) during alcohol withdrawal and abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 288-95. PMID 8873112 DOI: 10.1016/0893-133X(95)00212-V  0.705
1996 Musselman DL, Nemeroff CB. Depression and endocrine disorders: focus on the thyroid and adrenal system. The British Journal of Psychiatry. Supplement. 123-8. PMID 8864158 DOI: 10.1192/S0007125000298504  0.674
1996 Musselman DL, Tomer A, Manatunga AK, Knight BT, Porter MR, Kasey S, Marzec U, Harker LA, Nemeroff CB. Exaggerated platelet reactivity in major depression. The American Journal of Psychiatry. 153: 1313-7. PMID 8831440 DOI: 10.1176/Ajp.153.10.1313  0.643
1996 Krishnan KR, Tupler LA, Ritchie JC, McDonald WM, Knight DL, Nemeroff CB, Carroll BJ. Apolipoprotein E-epsilon 4 frequency in geriatric depression. Biological Psychiatry. 40: 69-71. PMID 8780857 DOI: 10.1016/0006-3223(95)00424-6  0.494
1996 Fossey MD, Lydiard RB, Ballenger JC, Laraia MT, Bissette G, Nemeroff CB. Cerebrospinal fluid corticotropin-releasing factor concentrations in patients with anxiety disorders and normal comparison subjects. Biological Psychiatry. 39: 703-7. PMID 8731457 DOI: 10.1016/0006-3223(95)00197-2  0.711
1996 Coplan JD, Andrews MW, Rosenblum LA, Owens MJ, Friedman S, Gorman JM, Nemeroff CB. Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders. Proceedings of the National Academy of Sciences of the United States of America. 93: 1619-23. PMID 8643680 DOI: 10.1073/Pnas.93.4.1619  0.672
1996 Ladd CO, Owens MJ, Nemeroff CB. Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation. Endocrinology. 137: 1212-8. PMID 8625891 DOI: 10.1210/endo.137.4.8625891  0.807
1996 Bissette G, Seidler FJ, Nemeroff CB, Slotkin TA. High affinity choline transporter status in Alzheimer's disease tissue from rapid autopsy. Annals of the New York Academy of Sciences. 777: 197-204. PMID 8624084 DOI: 10.1111/j.1749-6632.1996.tb34419.x  0.678
1996 Hartline KM, Owens MJ, Nemeroff CB. Postmortem and cerebrospinal fluid studies of corticotropin-releasing factor in humans. Annals of the New York Academy of Sciences. 780: 96-105. PMID 8602742 DOI: 10.1111/J.1749-6632.1996.Tb15114.X  0.628
1996 Pomara N, Deptula D, Nolan K, Tun H, Singh R, Leviste F, Ritchie J, Greenblatt DJ, Nemeroff CB. Differential effects of alprazolam and lorazepam on plasma cortisol in normal elderly Biological Psychiatry. 39: 624-625. DOI: 10.1016/0006-3223(96)84367-8  0.475
1995 See RE, Lynch AM, Aravagiri M, Nemeroff CB, Owens MJ. Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats. Brain Research. 704: 202-9. PMID 8788915 DOI: 10.1016/0006-8993(95)01114-5  0.65
1995 Sharma RP, Bissette G, Janicak PG, Davis JM, Nemeroff CB. Elevation of CSF somatostatin concentrations in mania. The American Journal of Psychiatry. 152: 1807-9. PMID 8526251 DOI: 10.1176/Ajp.152.12.1807  0.698
1995 McDaniel JS, Musselman DL, Porter MR, Reed DA, Nemeroff CB. Depression in patients with cancer. Diagnosis, biology, and treatment. Archives of General Psychiatry. 52: 89-99. PMID 7848055 DOI: 10.1001/Archpsyc.1995.03950140007002  0.64
1995 Cowley DS, Roy-Byrne PP, Radant A, Ritchie JC, Greenblatt DJ, Nemeroff CB, Hommer DW. Benzodiazepine sensitivity in panic disorder: effects of chronic alprazolam treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 147-57. PMID 7779243 DOI: 10.1016/0893-133X(94)00074-A  0.524
1995 Owens MJ, Mulchahey JJ, Kasckow JW, Plotsky PM, Nemeroff CB. Exposure to an antisense oligonucleotide decreases corticotropin-releasing factor receptor binding in rat pituitary cultures. Journal of Neurochemistry. 64: 2358-61. PMID 7722522 DOI: 10.1046/J.1471-4159.1995.64052358.X  0.658
1995 Stowe ZN, Nemeroff CB. Women at risk for postpartum-onset major depression. American Journal of Obstetrics and Gynecology. 173: 639-45. PMID 7645646 DOI: 10.1016/0002-9378(95)90296-1  0.594
1995 Kinkead B, Owens MJ, Nemeroff CB. Ontogeny of the effect of antipsychotic drug treatment on neurotensin concentrations in the rat brain. Synapse (New York, N.Y.). 20: 244-8. PMID 7570356 DOI: 10.1002/syn.890200308  0.772
1995 Kasckow JW, Han JH, Parkes DG, Mulchahey JJ, Owens MJ, Risby ED, Fisher J, Nemeroff CB. Regulation of corticotropin-releasing factor secretion and synthesis in the human neuroblastoma clones- BE(2)-M17 and BE(2)-C. Journal of Neuroendocrinology. 7: 461-6. PMID 7550293 DOI: 10.1111/J.1365-2826.1995.Tb00782.X  0.639
1995 Pitts AF, Samuelson SD, Meller WH, Bissette G, Nemeroff CB, Kathol RG. Cerebrospinal fluid corticotropin-releasing hormone, vasopressin, and oxytocin concentrations in treated patients with major depression and controls. Biological Psychiatry. 38: 330-5. PMID 7495928 DOI: 10.1016/0006-3223(95)00229-A  0.725
1995 Owens MJ, Ieni JR, Knight DL, Winders K, Nemeroff CB. The serotonergic antidepressant nefazodone inhibits the serotonin transporter: in vivo and ex vivo studies. Life Sciences. 57: PL373-80. PMID 7475971 DOI: 10.1016/0024-3205(95)02222-5  0.636
1995 Musselman DL, Nemeroff CB. Adrenal function in major depression Endocrinologist. 5: 91-96. DOI: 10.1097/00019616-199503000-00003  0.64
1995 Coplan JD, Andrews MW, Rosenblum LA, Owens MJ, Cooper T, Gorman JM, Nemeroff CB. P-5-2 Behavioral, monoaminergic, neuroendecrine and neuropeptidergic alterations in grown nonhuman primates exposed to unpredictable early rearing: relevance to human anxiety European Neuropsychopharmacology. 5: 353. DOI: 10.1016/0924-977X(95)90606-E  0.624
1995 Nemeroff C, Stout S, Owens M. S-29-3 Stress peptides and HPA axis reactivity in depression European Neuropsychopharmacology. 5: 242-243. DOI: 10.1016/0924-977X(95)90296-P  0.793
1995 Han J, Kasckow J, Parkes D, Owens M, Stipetic M, Breitman D, Kazanjian H, Nemeroff C. Regulation of CRF in BE (2)-M17 and BE (2)-C neuroblastoma cell lines Biological Psychiatry. 37: 647. DOI: 10.1016/0006-3223(95)94607-X  0.595
1995 Brunello N, Burrows GD, Jonsson B, Judd LL, Kasper S, Keller MB, Kupfer DJ, Lecrubier Y, Mendlewicz J, Montgomery SA, Nemeroff CB, Preskorn S, Racagni G, Rush AJ. Critical issues in the treatment of affective disorders Depression. 3: 187-198. DOI: 10.1002/Depr.3050030406  0.341
1994 Kasckow JW, Owens MJ, Stipetic MD, Han JH, Nemeroff CB. Corticotropin-releasing factor is secreted in the BE(2)-C neuroblastoma cell and is responsive to forskolin. Life Sciences. 54: 1825-9. PMID 8196496 DOI: 10.1016/0024-3205(94)90121-X  0.721
1994 Wall TL, Nemeroff CB, Ritchie JC, Ehlers CL. Cortisol responses following placebo and alcohol in Asians with different ALDH2 genotypes. Journal of Studies On Alcohol. 55: 207-13. PMID 8189741 DOI: 10.15288/Jsa.1994.55.207  0.458
1994 Lesem MD, Kaye WH, Bissette G, Jimerson DC, Nemeroff CB. Cerebrospinal fluid TRH immunoreactivity in anorexia nervosa. Biological Psychiatry. 35: 48-53. PMID 8167204 DOI: 10.1016/0006-3223(94)91167-3  0.701
1994 Slotkin TA, Nemeroff CB, Bissette G, Seidler FJ. Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies. The Journal of Clinical Investigation. 94: 696-702. PMID 8040324 DOI: 10.1172/JCI117387  0.674
1994 Forman SD, Bissette G, Yao J, Nemeroff CB, van Kammen DP. Cerebrospinal fluid corticotropin-releasing factor increases following haloperidol withdrawal in chronic schizophrenia. Schizophrenia Research. 12: 43-51. PMID 8018584 DOI: 10.1016/0920-9964(94)90083-3  0.738
1994 Andrews JM, Nemeroff CB. Contemporary management of depression. The American Journal of Medicine. 97: 24S-32S. PMID 7992823 DOI: 10.1016/0002-9343(94)90360-3  0.369
1994 Clement R, Griff D, Banks B, Nemeroff C, Kitabgi P, Bissette G. Effects of haloperidol, quinelorane, and lithium on regional neurotensin/neuromedin N concentrations: further evidence for neurotensin/neuromedin N-dopamine interactions. Synapse (New York, N.Y.). 17: 241-6. PMID 7992199 DOI: 10.1002/syn.890170405  0.714
1994 Rama Krishnan KR, Ritchie JC, Tupler LA, McDonald WM, Knight D, Nemeroff CB, Marcovina S. Apolipoprotein E epsilon 4. Neurology. 44: 2420-1. PMID 7991154 DOI: 10.1212/WNL.44.12.2420-a  0.426
1994 Sharma RP, Bissette G, Janicak P, Davis JM, Nemeroff CB. Cerebrospinal fluid somatostatin concentrations in schizophrenia and schizoaffective disorder: the effects of antipsychotic treatment. Schizophrenia Research. 13: 173-7. PMID 7986775 DOI: 10.1016/0920-9964(94)90099-X  0.7
1994 Kasckow JW, Parkes DG, Owens MJ, Stipetic MD, Han JH, Nemeroff CB, Vale WW. The BE (2)-M17 neuroblastoma cell line synthesizes and secretes corticotropin-releasing factor. Brain Research. 654: 159-62. PMID 7982090 DOI: 10.1016/0006-8993(94)91583-0  0.746
1994 Kinkead B, Nemeroff CB. The effects of typical and atypical antipsychotic drugs on neurotensin-containing neurons in the central nervous system. The Journal of Clinical Psychiatry. 55: 30-2. PMID 7961568  0.606
1994 Kasckow JW, Mulcahey JJ, Han JH, Owens MJ, Stipetic MD, Breitman D, Nemeroff CB. Interleukin-1 alpha induces corticotropin-releasing factor secretion and synthesis from NPLC-KC cells through various second messenger pathways. Synapse (New York, N.Y.). 18: 354-8. PMID 7886628 DOI: 10.1002/syn.890180411  0.704
1994 Weiss JM, Stout JC, Aaron MF, Quan N, Owens MJ, Butler PD, Nemeroff CB. Depression and anxiety: role of the locus coeruleus and corticotropin-releasing factor. Brain Research Bulletin. 35: 561-72. PMID 7859114 DOI: 10.1016/0361-9230(94)90170-8  0.759
1994 Hawley RJ, Nemeroff CB, Bissette G, Guidotti A, Rawlings R, Linnoila M. Neurochemical correlates of sympathetic activation during severe alcohol withdrawal. Alcoholism, Clinical and Experimental Research. 18: 1312-6. PMID 7695023 DOI: 10.1111/j.1530-0277.1994.tb01429.x  0.686
1994 Breslin NA, Suddath RL, Bissette G, Nemeroff CB, Lowrimore P, Weinberger DR. CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates. Schizophrenia Research. 12: 35-41. PMID 7517175 DOI: 10.1016/0920-9964(94)90082-5  0.704
1994 Roy A, Wolkowitz OM, Bissette G, Nemeroff CB. Differences in CSF concentrations of thyrotropin-releasing hormone in depressed patients and normal subjects: negative findings. The American Journal of Psychiatry. 151: 600-2. PMID 7511876 DOI: 10.1176/Ajp.151.4.600  0.725
1994 Owens MJ, Nemeroff CB. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical Chemistry. 40: 288-95. PMID 7508830 DOI: 10.1093/Clinchem/40.2.288  0.67
1994 Virkkunen M, Kallio E, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL. Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry. 51: 28-33. PMID 7506516 DOI: 10.1001/Archpsyc.1994.03950010028004  0.667
1994 Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL, Linnoila M. CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Archives of General Psychiatry. 51: 20-7. PMID 7506515 DOI: 10.1001/Archpsyc.1994.03950010020003  0.681
1994 Doraiswamy M, Krishnan R, Ritchie J, Tupler L, McDonald W, Marcovina S, Knight D, Nemeroff C. Apolipoprotein E4 In Late Onset Depression Neuropsychopharmacology. 11: 268-268. DOI: 10.1038/Sj.Npp.1380144  0.508
1994 Nemeroff C, Owens M, Owens C, Ehlers C, Robbins T, Levine S. The neurobiological consequences of early traumatic experiences: focus on corticotropin-releasing factor European Neuropsychopharmacology. 4: 255-256. DOI: 10.1016/0924-977X(94)90077-9  0.631
1994 Kasckow J, Owens M, Han J, Stipetic M, Nemeroff C. The BE(2)-C cell secretes corticotropin-releasing factor and responds to forskolin Biological Psychiatry. 35: 663. DOI: 10.1016/0006-3223(94)90833-8  0.623
1994 Stout SC, Nemeroff CB. Stress and psychiatric disorders Seminars in Neuroscience. 6: 271-280. DOI: 10.1006/Smns.1994.1034  0.727
1993 Koegler-Muly SM, Owens MJ, Ervin GN, Kilts CD, Nemeroff CB. Potential corticotropin-releasing factor pathways in the rat brain as determined by bilateral electrolytic lesions of the central amygdaloid nucleus and the paraventricular nucleus of the hypothalamus. Journal of Neuroendocrinology. 5: 95-8. PMID 8485547 DOI: 10.1111/J.1365-2826.1993.Tb00367.X  0.765
1993 Ehlers CL, Kaneko WM, Owens MJ, Nemeroff CB. Effects of gender and social isolation on electroencephalogram and neuroendocrine parameters in rats. Biological Psychiatry. 33: 358-66. PMID 8471694 DOI: 10.1016/0006-3223(93)90325-8  0.634
1993 Veith RC, Lewis N, Langohr JI, Murburg MM, Ashleigh EA, Castillo S, Peskind ER, Pascualy M, Bissette G, Nemeroff CB. Effect of desipramine on cerebrospinal fluid concentrations of corticotropin-releasing factor in human subjects. Psychiatry Research. 46: 1-8. PMID 8464952 DOI: 10.1016/0165-1781(93)90002-X  0.709
1993 Jolkkonen J, Lepola U, Bissette G, Nemeroff C, Riekkinen P. CSF corticotropin-releasing factor is not affected in panic disorder. Biological Psychiatry. 33: 136-8. PMID 8439604 DOI: 10.1016/0006-3223(93)90315-5  0.697
1993 Wenk GL, O'Leary M, Nemeroff CB, Bissette G, Moser H, Naidu S. Neurochemical alterations in Rett syndrome. Brain Research. Developmental Brain Research. 74: 67-72. PMID 8403377 DOI: 10.1016/0165-3806(93)90084-N  0.697
1993 Krishnan KR, Miller MN, Helms MJ, Reed D, Ritchie JC, Nemeroff CB, Carroll BJ. Dose response relationship between plasma ACTH and cortisol after the infusion of ACTH1-24. European Archives of Psychiatry and Clinical Neuroscience. 242: 240-3. PMID 8384887 DOI: 10.1007/BF02189969  0.5
1993 Blazer DG, Malmrose LC, Wallsten SM, Nemeroff CB, Reed DA, Ritchie JC, Tyrey ME. Rhythmicity and response to A.M. and P.M. CRH challenge in elderly subjects. Neurobiology of Aging. 14: 101-6. PMID 8383810 DOI: 10.1016/0197-4580(93)90029-B  0.494
1993 Fossey MD, Lydiard RB, Ballenger JC, Laraia MT, Bissette G, Nemeroff CB. Cerebrospinal fluid thyrotropin-releasing hormone concentrations in patients with anxiety disorders. The Journal of Neuropsychiatry and Clinical Neurosciences. 5: 335-7. PMID 8369645 DOI: 10.1176/Jnp.5.3.335  0.703
1993 Axelson DA, Doraiswamy PM, McDonald WM, Boyko OB, Tupler LA, Patterson LJ, Nemeroff CB, Ellinwood EH, Krishnan KR. Hypercortisolemia and hippocampal changes in depression. Psychiatry Research. 47: 163-73. PMID 8341769 DOI: 10.1016/0165-1781(93)90046-J  0.35
1993 Pihoker C, Owens MJ, Kuhn CM, Schanberg SM, Nemeroff CB. Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: a putative role for corticotropin-releasing factor. Psychoneuroendocrinology. 18: 485-93. PMID 8265736 DOI: 10.1016/0306-4530(93)90042-J  0.676
1993 Powchik P, Davidson M, Nemeroff CB, Haroutunian V, Purohit D, Losonczy M, Bissette G, Perl D, Ghanbari H, Miller B. Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment. The American Journal of Psychiatry. 150: 1726-7. PMID 8214183 DOI: 10.1176/Ajp.150.11.1726  0.667
1993 Owens MJ, Vargas MA, Nemeroff CB. The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: implications for a role for CRF in the pathogenesis of anxiety disorders. Journal of Psychiatric Research. 27: 209-20. PMID 8145178 DOI: 10.1016/0022-3956(93)90029-2  0.689
1993 Molchan SE, Hill JL, Martinez RA, Lawlor BA, Mellow AM, Rubinow DR, Bissette G, Nemeroff CB, Sunderland T. CSF somatostatin in Alzheimer's disease and major depression: relationship to hypothalamic-pituitary-adrenal axis and clinical measures. Psychoneuroendocrinology. 18: 509-19. PMID 7903467 DOI: 10.1016/0306-4530(93)90044-L  0.716
1993 Musselman DL, Nemeroff CB. The Role of Corticotropin-Releasing Factor in the Pathophysiology of Psychiatric Disorders Psychiatric Annals. 23: 676-681. DOI: 10.3928/0048-5713-19931201-07  0.631
1993 Owens MJ, Dole KC, Knight DL, Nemeroff CB. Preclinical evaluation of the putative antidepressant nefazodone Depression. 1: 315-323. DOI: 10.1002/DEPR.3050010606  0.661
1993 Krishnan KRR, Rayasam K, Reed D, Smith M, Chapell P, Saunders WB, Ritchie JC, Carroll BJ, Nemeroff CB. The corticotropin releasing factor stimulation test in patients with major depression: Relationship to dexamethasone suppression test results Depression. 1: 133-136. DOI: 10.1002/DEPR.3050010303  0.571
1992 Vargas MA, Bissette G, Owens MJ, Ehlers CL, Nemeroff CB. Effects of chronic ethanol and benzodiazepine treatment and withdrawal on corticotropin-releasing factor neural systems. Annals of the New York Academy of Sciences. 654: 145-52. PMID 1632579 DOI: 10.1111/J.1749-6632.1992.Tb25963.X  0.775
1992 Krishnan KR, McDonald WM, Escalona PR, Doraiswamy PM, Na C, Husain MM, Figiel GS, Boyko OB, Ellinwood EH, Nemeroff CB. Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Archives of General Psychiatry. 49: 553-7. PMID 1627046 DOI: 10.1001/Archpsyc.1992.01820070047007  0.352
1992 Levant B, Nemeroff CB. Further studies on the modulation of regional brain neurotensin concentrations by antipsychotic drugs: focus on haloperidol and BMY 14802. The Journal of Pharmacology and Experimental Therapeutics. 262: 348-55. PMID 1625208  0.569
1992 Ehlers CL, Chaplin RI, Wall TL, Lumeng L, Li TK, Owens MJ, Nemeroff CB. Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats. Psychopharmacology. 106: 359-64. PMID 1570383 DOI: 10.1007/Bf02245418  0.652
1992 Owens MJ, Ritchie JC, Nemeroff CB. 5 alpha-pregnane-3 alpha, 21-diol-20-one (THDOC) attenuates mild stress-induced increases in plasma corticosterone via a non-glucocorticoid mechanism: comparison with alprazolam. Brain Research. 573: 353-5. PMID 1504771 DOI: 10.1016/0006-8993(92)90788-B  0.71
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. Cerebrospinal fluid neuropeptides in dementia. Biological Psychiatry. 32: 452-6. PMID 1486150 DOI: 10.1016/0006-3223(92)90132-J  0.71
1992 Axelson DA, Doraiswamy PM, Boyko OB, Rodrigo Escalona P, McDonald WM, Ritchie JC, Patterson LJ, Ellinwood EH, Nemeroff CB, Krishnan KR. In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients. Psychiatry Research. 44: 63-70. PMID 1461948 DOI: 10.1016/0165-1781(92)90070-J  0.519
1992 Cain ST, Bissette G, Kilts CD, Nemeroff CB. A commentary on methods in peptide neurobiology: focus on neurotensin. Critical Reviews in Neurobiology. 6: 233-41. PMID 1423691  0.644
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. Cerebrospinal-fluid neuropeptides: a biochemical subgrouping approach. Neuropsychobiology. 26: 37-42. PMID 1361969 DOI: 10.1159/000118894  0.701
1992 Kilts CD, Coco ML, Ely TD, Bissette G, Nemeroff CB. Differential effects of conditioned and unconditioned stress on the neurotensin content of dopamine cell body groups of the ventral mesencephalon. Annals of the New York Academy of Sciences. 668: 266-76. PMID 1361117 DOI: 10.1111/j.1749-6632.1992.tb27355.x  0.703
1992 Nemeroff CB, Levant B, Myers B, Bissette G. Neurotensin, antipsychotic drugs, and schizophrenia. Basic and clinical studies. Annals of the New York Academy of Sciences. 668: 146-56. PMID 1361110 DOI: 10.1111/j.1749-6632.1992.tb27346.x  0.743
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. CSF corticotropin releasing hormone, somatostatin, and thyrotropin releasing hormone in schizophrenia. Psychiatry Research. 43: 13-21. PMID 1359593 DOI: 10.1016/0165-1781(92)90137-R  0.707
1992 Bissette G, Nemeroff CB. Biochemical and neuropeptide alterations in Alzheimer's disease. Clinical Neuropharmacology. 15: 33A-34A. PMID 1354039 DOI: 10.1097/00002826-199201001-00019  0.661
1992 Nemeroff CB, Knight DL, Bissette G. Somatostatin: a neuropeptide system pathologically altered in Alzheimer's disease and depression. Clinical Neuropharmacology. 15: 311A-312A. PMID 1354038 DOI: 10.1097/00002826-199201001-00161  0.697
1992 Owens MJ, Nemeroff CB. Stress, corticotropin-releasing factor neurons, and the actions of benzodiazepines. Clinical Neuropharmacology. 15: 155A-156A. PMID 1354023 DOI: 10.1097/00002826-199201001-00083  0.64
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. CSF corticotropin-releasing hormone and somatostatin in major depression: response to antidepressant treatment and relapse. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 2: 107-13. PMID 1352999 DOI: 10.1016/0924-977X(92)90019-5  0.732
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. Cerebrospinal fluid neuropeptides in mood disorder and dementia. Journal of Affective Disorders. 25: 39-45. PMID 1352520 DOI: 10.1016/0165-0327(92)90091-J  0.726
1992 Levant B, Merchant KM, Dorsa DM, Nemeroff CB. BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum. Brain Research. Molecular Brain Research. 12: 279-84. PMID 1349718 DOI: 10.1016/0169-328X(92)90130-4  0.6
1992 Myers B, Levant B, Bissette G, Nemeroff CB. Pharmacological specificity of the increase in neurotensin concentrations after antipsychotic drug treatment. Brain Research. 575: 325-8. PMID 1349254 DOI: 10.1016/0006-8993(92)90098-T  0.777
1992 Krishnan KR, Reed D, Wilson WH, Saunders WB, Ritchie JC, Nemeroff CB, Carroll BJ. RU486 in depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 16: 913-20. PMID 1325068 DOI: 10.1016/0278-5846(92)90109-R  0.557
1992 BISSETTE G, LEVANT B, NEMEROFF C. A POTENTIAL ROLE FOR NEUROTENSIN IN MEDIATING THE THERAPEUTIC EFFECTS OF ANTIPSYCHOTIC DRUGS Behavioural Pharmacology. 3: 17. DOI: 10.1097/00008877-199204001-00049  0.735
1992 Banki CM, Karmacsi L, Bissette G, Nemeroff CB. CSF THYROTROPIN-RELEASING HORMONE IN PSYCHIATRIC DISORDERS Clinical Neuropharmacology. 15: 31B. DOI: 10.1097/00002826-199202001-00058  0.699
1992 Nemeroff C, Owens M. Serotonin antagonists as antipsychotic drugs European Neuropsychopharmacology. 2: 287. DOI: 10.1016/0924-977X(92)90119-S  0.623
1991 Figiel GS, Krishnan KRR, Rao VP, Doraiswamy M, Ellinwood EH, Nemeroff CB, Evans D, Boyko O. Subcortical hyperintensities on brain magnetic resonance imaging: A comparison of normal and bipolar subjects Journal of Neuropsychiatry and Clinical Neurosciences. 3: 18-22. PMID 7580167 DOI: 10.1176/Jnp.3.1.18  0.475
1991 Golden RN, McCartney CF, Haggerty JJ, Raft D, Nemeroff CB, Ekstrom D, Holmes V, Simon JS, Droba M, Quade D. The detection of depression by patient self-report in women with gynecologic cancer. International Journal of Psychiatry in Medicine. 21: 17-27. PMID 2066254 DOI: 10.2190/Hw7K-B3P8-3T8H-073M  0.509
1991 Lammers CH, Doraiswamy PM, Husain MM, Figiel GS, Lurie SN, Boyko OB, Ellinwood EH, Nemeroff CB, Krishnan KR. MRI of corpus callosum and septum pellucidum in depression. Biological Psychiatry. 29: 300-1. PMID 2015336 DOI: 10.1016/0006-3223(91)91297-5  0.302
1991 Garver DL, Bissette G, Yao JK, Nemeroff CB. Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients. The American Journal of Psychiatry. 148: 484-8. PMID 2006695 DOI: 10.1176/Ajp.148.4.484  0.714
1991 Krishnan KR, Doraiswamy PM, Lurie SN, Figiel GS, Husain MM, Boyko OB, Ellinwood EH, Nemeroff CB. Pituitary size in depression. The Journal of Clinical Endocrinology and Metabolism. 72: 256-9. PMID 1991797 DOI: 10.1210/Jcem-72-2-256  0.341
1991 Cain ST, Owens MJ, Nemeroff CB. Subcellular distribution of corticotropin-releasing-factor-like immunoreactivity in rat central nervous system. Neuroendocrinology. 54: 36-41. PMID 1922675 DOI: 10.1159/000125848  0.64
1991 Stowe ZN, Nemeroff CB. The electrophysiological actions of neurotensin in the central nervous system. Life Sciences. 49: 987-1002. PMID 1890928 DOI: 10.1016/0024-3205(91)90300-Z  0.58
1991 Figiel GS, Krishnan KR, Doraiswamy PM, Rao VP, Nemeroff CB, Boyko OB. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison between late age onset and early onset elderly depressed subjects. Neurobiology of Aging. 12: 245-7. PMID 1876230 DOI: 10.1016/0197-4580(91)90104-R  0.319
1991 Owens MJ, Overstreet DH, Knight DL, Rezvani AH, Ritchie JC, Bissette G, Janowsky DS, Nemeroff CB. Alterations in the hypothalamic-pituitary-adrenal axis in a proposed animal model of depression with genetic muscarinic supersensitivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 4: 87-93. PMID 1851013  0.809
1991 Owens MJ, Knight DL, Ritchie JC, Nemeroff CB. The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration. The Journal of Pharmacology and Experimental Therapeutics. 256: 795-800. PMID 1847213  0.712
1991 Owens MJ, Knight DL, Ritchie JC, Nemeroff CB. The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 256: 787-94. PMID 1847212  0.724
1991 Krishnan KR, Doraiswamy PM, Figiel GS, Husain MM, Shah SA, Na C, Boyko OB, McDonald WM, Nemeroff CB, Ellinwood EH. Hippocampal abnormalities in depression. The Journal of Neuropsychiatry and Clinical Neurosciences. 3: 387-91. PMID 1821258 DOI: 10.1176/Jnp.3.4.387  0.323
1991 Husain MM, McDonald WM, Doraiswamy PM, Figiel GS, Na C, Escalona PR, Boyko OB, Nemeroff CB, Krishnan KR. A magnetic resonance imaging study of putamen nuclei in major depression. Psychiatry Research. 40: 95-9. PMID 1763144 DOI: 10.1016/0925-4927(91)90001-7  0.342
1991 Bissette G, Smith WH, Dole KC, Crain B, Ghanbari H, Miller B, Nemeroff CB. Alterations in Alzheimer's disease-associated protein in Alzheimer's disease frontal and temporal cortex. Archives of General Psychiatry. 48: 1009-12. PMID 1747015 DOI: 10.1001/Archpsyc.1991.01810350049007  0.661
1991 Paris JM, Lorens SA, Lee JM, Mitsushio H, Ritchie JC, Nemeroff CB. Muscimol injections into the median raphe nucleus increase serum ACTH and corticosterone concentrations via a nonserotonergic mechanism. Pharmacology, Biochemistry, and Behavior. 39: 765-8. PMID 1723800 DOI: 10.1016/0091-3057(91)90161-T  0.521
1991 Nemeroff CB, Bissette G, Slotkin TA, Seidler FJ, Miller BE, Ghanbari H. Recent advances in the neurochemical pathology of Alzheimer's disease. Studies of neuropeptides, cholinergic function and Alzheimer's disease-associated protein. Annals of the New York Academy of Sciences. 640: 193-6. PMID 1685644 DOI: 10.1111/j.1749-6632.1991.tb00216.x  0.672
1991 Levant B, Bissette G, Davis MD, Heffner TG, Nemeroff CB. Effects of CI-943, a potential antipsychotic drug, and haloperidol on regional brain neurotensin concentrations. Synapse (New York, N.Y.). 9: 225-30. PMID 1685600 DOI: 10.1002/syn.890090309  0.777
1991 Jolkkonen J, Hartikainen P, Soikkeli R, Bissette G, Nemeroff C, Riekkinen P. A correlation study of CSF neuropeptides in Alzheimer's and Parkinson's disease. Neuropeptides. 19: 97-102. PMID 1682848 DOI: 10.1016/0143-4179(91)90138-9  0.683
1991 Stowe ZN, Bissette G, Nemeroff CB. Neurotensin-dopamine interactions: relevance to schizophrenia and the action of antipsychotic drugs. Yakubutsu, Seishin, KåDå = Japanese Journal of Psychopharmacology. 11: 49-59. PMID 1679273  0.743
1991 Levant B, Bissette G, Widerlöv E, Nemeroff CB. Alterations in regional brain neurotensin concentrations produced by atypical antipsychotic drugs. Regulatory Peptides. 32: 193-201. PMID 1674615 DOI: 10.1016/0167-0115(91)90046-J  0.771
1991 Nemeroff CB, Bissette G, Akil H, Fink M. Neuropeptide concentrations in the cerebrospinal fluid of depressed patients treated with electroconvulsive therapy. Corticotrophin-releasing factor, beta-endorphin and somatostatin. The British Journal of Psychiatry : the Journal of Mental Science. 158: 59-63. PMID 1673078 DOI: 10.1192/BJP.158.1.59  0.713
1991 Nemeroff CB, Kilts CD, Levant B, Bissette G, Campbell A, Baldessarini RJ. Effects of the isomers of N-n-propylnorapomorphine and haloperidol on regional concentrations of neurotensin in rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 4: 27-33. PMID 1672249  0.76
1991 Krishnan KR, Ritchie JC, Manepalli AN, Saunders W, Li SW, Venkataraman S, Nemeroff CB, Carroll BJ. Fast feedback regulation of ACTH by cortisol. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 15: 523-9. PMID 1661015 DOI: 10.1016/0278-5846(91)90027-X  0.503
1991 Adinoff B, Nemeroff CB, Bissette G, Martin PR, Linnoila M. Inverse relationship between CSF TRH concentrations and the TSH response to TRH in abstinent alcohol-dependent patients. The American Journal of Psychiatry. 148: 1586-8. PMID 1656797 DOI: 10.1176/Ajp.148.11.1586  0.699
1991 Roy-Byrne PP, Cowley DS, Hommer D, Ritchie J, Greenblatt D, Nemeroff C. Neuroendocrine effects of diazepam in panic and generalized anxiety disorders Biological Psychiatry. 30: 73-80. PMID 1654136 DOI: 10.1016/0006-3223(91)90072-T  0.526
1991 Husain MM, Knight DL, Doraiswamy PM, Figiel GS, McDonald WM, Boyko OB, Krishnan KR, Nemeroff CB. Platelet [3H]-imipramine binding and leukoencephalopathy in geriatric depression. Biological Psychiatry. 29: 665-70. PMID 1647227 DOI: 10.1016/0006-3223(91)90136-A  0.32
1991 Appel NM, Owens MJ, Culp S, Zaczek R, Contrera JF, Bissette G, Nemeroff CB, De Souza EB. Role for brain corticotropin-releasing factor in the weight-reducing effects of chronic fenfluramine treatment in rats. Endocrinology. 128: 3237-46. PMID 1645265 DOI: 10.1210/endo-128-6-3237  0.8
1990 Krishnan KR, Ritchie JC, Saunders WB, Nemeroff CB, Carroll BJ. Adrenocortical sensitivity to low-dose ACTH administration in depressed patients. Biological Psychiatry. 27: 930-3. PMID 2331499 DOI: 10.1016/0006-3223(90)90476-I  0.539
1990 Slotkin TA, Seidler FJ, Crain BJ, Bell JM, Bissette G, Nemeroff CB. Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy. Proceedings of the National Academy of Sciences of the United States of America. 87: 2452-5. PMID 2320567 DOI: 10.1073/Pnas.87.7.2452  0.68
1990 Butler PD, Weiss JM, Stout JC, Nemeroff CB. Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 176-83. PMID 2299391 DOI: 10.1523/Jneurosci.10-01-00176.1990  0.588
1990 Haggerty JJ, Evans DL, Golden RN, Pedersen CA, Simon JS, Nemeroff CB. The presence of antithyroid antibodies in patients with affective and nonaffective psychiatric disorders. Biological Psychiatry. 27: 51-60. PMID 2297552 DOI: 10.1016/0006-3223(90)90019-X  0.607
1990 Ritchie JC, Belkin BM, Krishnan KR, Nemeroff CB, Carroll BJ. Plasma dexamethasone concentrations and the dexamethasone suppression test. Biological Psychiatry. 27: 159-73. PMID 2294980 DOI: 10.1016/0006-3223(90)90646-J  0.536
1990 Gupta SK, Krishnan RR, Ellinwood EH, Ritchie JC, Nemeroff CB. Pharmacokinetics of growth hormone secretion in humans induced by growth hormone releasing hormone. Life Sciences. 47: 1887-93. PMID 2266772 DOI: 10.1016/0024-3205(90)90400-L  0.493
1990 Haggerty JJ, Garbutt JC, Evans DL, Golden RN, Pedersen C, Simon JS, Nemeroff CB. Subclinical hypothyroidism: a review of neuropsychiatric aspects. International Journal of Psychiatry in Medicine. 20: 193-208. PMID 2203696 DOI: 10.2190/Adly-1Uu0-1A8L-Hpxy  0.599
1990 Ghanbari HA, Miller BE, Haigler HJ, Arato M, Bissette G, Davies P, Nemeroff CB, Perry EK, Perry R, Ravid R. Biochemical assay of Alzheimer's disease--associated protein(s) in human brain tissue. A clinical study. Jama. 263: 2907-10. PMID 2187102 DOI: 10.1001/Jama.1990.03440210057032  0.673
1990 Krishnan KR, Ritchie JC, Saunders W, Wilson W, Nemeroff CB, Carroll BJ. Nocturnal and early morning secretion of ACTH and cortisol in humans. Biological Psychiatry. 28: 47-57. PMID 2165424 DOI: 10.1016/0006-3223(90)90431-Z  0.493
1990 Nemeroff CB, Krishnan KR, Blazer DG, Knight DL, Benjamin D, Meyerson LR. Elevated plasma concentrations of alpha 1-acid glycoprotein, a putative endogenous inhibitor of the tritiated imipramine binding site, in depressed patients. Archives of General Psychiatry. 47: 337-40. PMID 2157380 DOI: 10.1001/Archpsyc.1990.01810160037007  0.34
1990 Owens MJ, Bartolome J, Schanberg SM, Nemeroff CB. Corticotropin-releasing factor concentrations exhibit an apparent diurnal rhythm in hypothalamic and extrahypothalamic brain regions: differential sensitivity to corticosterone. Neuroendocrinology. 52: 626-31. PMID 2126613 DOI: 10.1159/000125655  0.665
1990 Levant B, Nemeroff CB. Sigma receptor "antagonist" BMY 14802 increases neurotensin concentrations in the rat nucleus accumbens and caudate. The Journal of Pharmacology and Experimental Therapeutics. 254: 330-5. PMID 1973198  0.575
1990 Krystal A, Krishnan KR, Raitiere M, Poland R, Ritchie JC, Dunnick NR, Hanada K, Nemeroff CB. Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder. The Journal of Neuropsychiatry and Clinical Neurosciences. 2: 34-43. PMID 1967010 DOI: 10.1176/Jnp.2.1.34  0.517
1990 Owens MJ, Edwards E, Nemeroff CB. Effects of 5-HT1A receptor agonists on hypothalamo-pituitary-adrenal axis activity and corticotropin-releasing factor containing neurons in the rat brain. European Journal of Pharmacology. 190: 113-22. PMID 1963847 DOI: 10.1016/0014-2999(90)94118-H  0.684
1990 Roy A, Bissette G, Nemeroff CB, DeJong J, Ravitz B, Adinoff B, Linnoila M. Cerebrospinal fluid thyrotropin-releasing hormone concentrations in alcoholics and normal controls. Biological Psychiatry. 28: 767-72. PMID 1701664 DOI: 10.1016/0006-3223(90)90512-Z  0.696
1990 Urban B, France R, Bissette G, Nemeroff C. Do CSF concentrations of somatostatin change with pain clinic therapy in chronic low back pain patients? Pain. 41: S460. DOI: 10.1016/0304-3959(90)93036-W  0.661
1990 Nemeroff CB, Weiss JM, Bissette G, Owens MJ. Evidence for a role for corticotropin-releasing factor in the pathogenesis of anxiety disorders and in the action of triazolobenzodiazepines Journal of Psychiatric Research. 24: 90-91. DOI: 10.1016/0022-3956(90)90103-W  0.788
1989 Rao VP, Krishnan KRR, Goli V, Saunders WB, Ellinwood EH, Blazer DG, Nemeroff CB. Neuroanatomical changes and hypothalamo-pituitary-adrenal axis abnormalities☆ Biological Psychiatry. 26: 729-732. PMID 2804193 DOI: 10.1016/0006-3223(89)90108-X  0.312
1989 Levant B, Bissette G, Nemeroff CB. Effects of anticholinergic drugs on regional brain neurotensin concentrations. European Journal of Pharmacology. 165: 327-30. PMID 2776835 DOI: 10.1016/0014-2999(89)90731-0  0.768
1989 Radke JM, MacLennan AJ, Beinfeld MC, Bissette G, Nemeroff CB, Vincent SR, Fibiger HC. Effects of short- and long-term haloperidol administration and withdrawal on regional brain cholecystokinin and neurotensin concentrations in the rat. Brain Research. 480: 178-83. PMID 2713650 DOI: 10.1016/0006-8993(89)91580-1  0.696
1989 Nemeroff CB, Bissette G, Widerlov E, Beckmann H, Gerner R, Manberg PJ, Lindstrom L, Prange AJ, Gattaz WF. Neurotensin-like immunoreactivity in cerebrospinal fluid of patients with schizophrenia, depression, anorexia nervosa-bulimia, and premenstrual syndrome. The Journal of Neuropsychiatry and Clinical Neurosciences. 1: 16-20. PMID 2577718 DOI: 10.1176/Jnp.1.1.16  0.711
1989 Owens MJ, Bissette G, Nemeroff CB. Acute effects of alprazolam and adinazolam on the concentrations of corticotropin-releasing factor in the rat brain. Synapse (New York, N.Y.). 4: 196-202. PMID 2575286 DOI: 10.1002/syn.890040304  0.819
1989 Nemeroff CB, Kizer JS, Reynolds GP, Bissette G. Neuropeptides in Alzheimer's disease: a postmortem study. Regulatory Peptides. 25: 123-30. PMID 2566190 DOI: 10.1016/0167-0115(89)90254-1  0.704
1989 Cook LL, Bissette G, Dole K, Nemeroff CB. A critical evaluation of cysteamine as a tool to deplete somatostatin in the rat central nervous system. Endocrinology. 124: 855-61. PMID 2563244 DOI: 10.1210/endo-124-2-855  0.705
1989 Smith MA, Davidson J, Ritchie JC, Kudler H, Lipper S, Chappell P, Nemeroff CB. The corticotropin-releasing hormone test in patients with posttraumatic stress disorder. Biological Psychiatry. 26: 349-55. PMID 2548631 DOI: 10.1016/0006-3223(89)90050-4  0.558
1989 Slotkin TA, Whitmore WL, Barnes GA, Krishnan KRR, Blazer DG, Knight DL, Nemeroff CB. Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression Biological Psychiatry. 25: 687-691. PMID 2538161 DOI: 10.1016/0006-3223(89)90238-2  0.33
1989 Arató M, Bánki CM, Bissette G, Nemeroff CB. Elevated CSF CRF in suicide victims. Biological Psychiatry. 25: 355-9. PMID 2536563 DOI: 10.1016/0006-3223(89)90183-2  0.67
1989 Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, Rivier JE, Thorner MO. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 50: 663-6. PMID 2515465 DOI: 10.1159/000125296  0.58
1989 Pomara N, Singh RR, Deptula D, LeWitt PA, Bissette G, Stanley M, Nemeroff CB. CSF corticotropin-releasing factor (CRF) in Alzheimer's disease: its relationship to severity of dementia and monoamine metabolites. Biological Psychiatry. 26: 500-4. PMID 2477071 DOI: 10.1016/0006-3223(89)90071-1  0.7
1989 Whitnall MH, Bernardini R, Chiarenza A, Calogero AE, Gold PW, Chrousos GP, Schwartz J, Canny B, Vale WW, Funder JW, Carlos LLD, Greene GL, Morrell JI, Amico JA, Levin SC, ... ... Nemeroff CB, et al. Subject Index Vol. 50, 1989 Neuroendocrinology. 50: 726-728. DOI: 10.1159/000125307  0.432
1989 Whitnall MH, Bernardini R, Chiarenza A, Calogero AE, Gold PW, Chrousos GP, Schwartz J, Canny B, Vale WW, Funder JW, Carlos LLD, Greene GL, Morrell JI, Amico JA, Levin SC, ... ... Nemeroff CB, et al. Contents, Vol. 50, 1989 Neuroendocrinology. 50. DOI: 10.1159/000125289  0.424
1989 Nemeroff CB, Evans DL. Thyrotropin-releasing hormone (TRH), the thyroid axis, and affective disorder. Annals of the New York Academy of Sciences. 553: 304-310. DOI: 10.1111/J.1749-6632.1989.Tb54497.X  0.491
1988 Simon JS, Evans DL, Nemeroff CB. The dexamethasone suppression test and antidepressant response in major depression. Journal of Psychiatric Research. 21: 313-7. PMID 3681765 DOI: 10.1016/0022-3956(87)90033-1  0.527
1988 Antelman SM, Knopf S, Kocan D, Edwards DJ, Ritchie JC, Nemeroff CB. One stressful event blocks multiple actions of diazepam for up to at least a month. Brain Research. 445: 380-5. PMID 3370472 DOI: 10.1016/0006-8993(88)91204-8  0.517
1988 Kilts CD, Anderson CM, Bissette G, Ely TD, Nemeroff CB. Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei. Biochemical Pharmacology. 37: 1547-54. PMID 3358784 DOI: 10.1016/0006-2952(88)90017-2  0.719
1988 Evans DL, McCartney CF, Haggerty JJ, Nemeroff CB, Golden RN, Simon JB, Quade D, Holmes V, Droba M, Mason GA. Treatment of depression in cancer patients is associated with better life adaptation: a pilot study. Psychosomatic Medicine. 50: 73-6. PMID 3344305 DOI: 10.1097/00006842-198801000-00009  0.628
1988 Ervin GN, Nemeroff CB. Antagonization of the behavioral activation produced by direct stimulation of forebrain dopamine receptors caused by intraaccumbens injections of neurotensin. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 1: 243-50. PMID 3150806 DOI: 10.1016/0893-133X(88)90024-3  0.652
1988 Banki CM, Bissette G, Arato M, Nemeroff CB. Elevation of immunoreactive CSF TRH in depressed patients. The American Journal of Psychiatry. 145: 1526-31. PMID 3143269 DOI: 10.1176/Ajp.145.12.1526  0.733
1988 Ervin GN, Nemeroff CB. Interactions of neurotensin with dopamine-containing neurons in the central nervous system. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: S53-69. PMID 3074341 DOI: 10.1016/0278-5846(88)90073-5  0.658
1988 Nemeroff CB, Bissette G. Neuropeptides, dopamine, and schizophrenia. Annals of the New York Academy of Sciences. 537: 273-91. PMID 3059929 DOI: 10.1111/J.1749-6632.1988.Tb42113.X  0.667
1988 Urban BJ, France RD, Bissette G, Spielman FJ, Nemeroff CB. Alterations in cerebrospinal fluid concentrations of somatostatin-like immunoreactivity in chronic pain patients. Pain. 33: 169-72. PMID 2967947 DOI: 10.1016/0304-3959(88)90087-5  0.673
1988 Krishnan KR, Manepalli AN, Ritchie JC, Rayasam K, Melville ML, Thorner MO, Rivier JE, Vale WW, Nemeroff CB. Growth hormone response to growth hormone-releasing factor in depression. Peptides. 9: 113-6. PMID 2856637 DOI: 10.1016/0196-9781(88)90234-3  0.548
1988 Bissette G, Nemeroff CB. Neurotensin and the mesocorticolimbic dopamine system. Annals of the New York Academy of Sciences. 537: 397-404. PMID 2849357 DOI: 10.1111/J.1749-6632.1988.Tb42122.X  0.664
1988 Nemeroff CB, Knight DL, Krishnan RR, Slotkin TA, Bissette G, Melville ML, Blazer DG. Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression. Archives of General Psychiatry. 45: 919-23. PMID 2844132 DOI: 10.1001/Archpsyc.1988.01800340045006  0.699
1988 Nemeroff CB, Owens MJ, Bissette G, Andorn AC, Stanley M. Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims. Archives of General Psychiatry. 45: 577-9. PMID 2837159 DOI: 10.1001/archpsyc.1988.01800300075009  0.803
1988 Krishnan KR, Ritchie JC, Manepalli AN, Nemeroff CB, Carroll BJ. Adrenocortical sensitivity to ACTH in humans. Biological Psychiatry. 24: 105-8. PMID 2836000 DOI: 10.1016/0006-3223(88)90130-8  0.513
1988 Krishnan KR, Manepalli AN, Ritchie JC, Rayasam K, Melville ML, Daughtry G, Thorner MO, Rivier JE, Vale WW, Nemeroff CB. Growth hormone-releasing factor stimulation test in depression. The American Journal of Psychiatry. 145: 90-2. PMID 2827532 DOI: 10.1176/AJP.145.1.90  0.586
1988 Bissette G, Dauer WT, Kilts CD, O'Connor L, Nemeroff CB. The effect of the stereoisomers of butaclamol on neurotensin content in discrete regions of the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 1: 329-35. PMID 2472151  0.774
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