William T. Dauer - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
neurology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shin JY, Hernandez-Ono A, Fedotova T, Östlund C, Lee MJ, Gibeley SB, Liang CC, Dauer WT, Ginsberg HN, Worman HJ. Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis. The Journal of Clinical Investigation. 130. PMID 31408437 DOI: 10.1172/JCI129769  0.56
2017 Pappas SS, Liang CC, Kim S, Rivera CO, Dauer WT. TorsinA dysfunction causes persistent neuronal nuclear pore defects. Human Molecular Genetics. PMID 29186574 DOI: 10.1093/hmg/ddx405  0.56
2017 Yellajoshyula D, Liang CC, Pappas SS, Penati S, Yang A, Mecano R, Kumaran R, Jou S, Cookson MR, Dauer WT. The DYT6 Dystonia Protein THAP1 Regulates Myelination within the Oligodendrocyte Lineage. Developmental Cell. 42: 52-67.e4. PMID 28697333 DOI: 10.1016/j.devcel.2017.06.009  0.56
2017 Saunders CA, Harris NJ, Willey PT, Woolums BM, Wang Y, McQuown AJ, Schoenhofen A, Worman HJ, Dauer WT, Gundersen GG, Luxton GW. TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement. The Journal of Cell Biology. PMID 28242745 DOI: 10.1083/jcb.201507113  0.48
2016 Shin JY, Méndez-López I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ. Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth. Human Molecular Genetics. PMID 27798115 DOI: 10.1093/hmg/ddw368  0.48
2016 Tanabe LM, Liang CC, Dauer WT. Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs. Cell Reports. 16: 3322-33. PMID 27653693 DOI: 10.1016/j.celrep.2016.08.044  0.64
2015 Weisheit CE, Dauer WT. A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation. Human Molecular Genetics. 24: 6459-72. PMID 26370418 DOI: 10.1093/hmg/ddv355  0.64
2015 Goodchild RE, Buchwalter AL, Naismith TV, Holbrook K, Billion K, Dauer WT, Liang CC, Dear ML, Hanson PI. Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum. Journal of Cell Science. PMID 26092934 DOI: 10.1242/jcs.167452  0.56
2015 Pappas SS, Darr K, Holley SM, Cepeda C, Mabrouk OS, Wong JM, LeWitt TM, Paudel R, Houlden H, Kennedy RT, Levine MS, Dauer WT. Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons. Elife. 4. PMID 26052670 DOI: 10.7554/eLife.08352  0.64
2015 Kett LR, Stiller B, Bernath MM, Tasset I, Blesa J, Jackson-Lewis V, Chan RB, Zhou B, Di Paolo G, Przedborski S, Cuervo AM, Dauer WT. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5724-42. PMID 25855184 DOI: 10.1523/JNEUROSCI.0632-14.2015  0.64
2015 VanGompel MJ, Nguyen KC, Hall DH, Dauer WT, Rose LS. A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. Molecular Biology of the Cell. 26: 1752-63. PMID 25739455 DOI: 10.1091/mbc.E14-07-1239  0.64
2015 Jankovic J, Bressman S, Dauer W, Kang UJ. Clinical and scientific perspectives on movement disorders: Stanley Fahn's contributions Movement Disorders. 30: 1862-1869. DOI: 10.1002/mds.26445  0.64
2014 Dauer WT. Neurogenetic disease: genes, mechanisms, and future promise. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 697-8. PMID 25261113 DOI: 10.1007/s13311-014-0303-0  0.64
2014 Worman HJ, Dauer WT. The nuclear envelope: an intriguing focal point for neurogenetic disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 764-72. PMID 25119890 DOI: 10.1007/s13311-014-0296-8  0.64
2014 Maric M, Haugo AC, Dauer W, Johnson D, Roller RJ. Nuclear envelope breakdown induced by herpes simplex virus type 1 involves the activity of viral fusion proteins. Virology. 460: 128-37. PMID 25010278 DOI: 10.1016/j.virol.2014.05.010  0.64
2014 Pappas SS, Leventhal DK, Albin RL, Dauer WT. Mouse models of neurodevelopmental disease of the basal ganglia and associated circuits. Current Topics in Developmental Biology. 109: 97-169. PMID 24947237 DOI: 10.1016/B978-0-12-397920-9.00001-9  0.64
2014 Liang CC, Tanabe LM, Jou S, Chi F, Dauer WT. TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration. The Journal of Clinical Investigation. 124: 3080-92. PMID 24937429 DOI: 10.1172/JCI72830  0.64
2014 Bohnen N, Sarter M, Muller M, Dauer W, Albin R. Author response. Neurology. 82: 1568-9. PMID 24895748 DOI: 10.1212/WNL.0000000000000607  0.64
2014 Shin JY, Le Dour C, Sera F, Iwata S, Homma S, Joseph LC, Morrow JP, Dauer WT, Worman HJ. Depletion of lamina-associated polypeptide 1 from cardiomyocytes causes cardiac dysfunction in mice. Nucleus (Austin, Tex.). 5: 260-459. PMID 24859316 DOI: 10.4161/nucl.29227  0.64
2014 Albin RL, Dauer WT. Magic shotgun for Parkinson's disease? Brain : a Journal of Neurology. 137: 1274-5. PMID 24771397 DOI: 10.1093/brain/awu076  0.64
2014 Dauer WT, Guo M. Multiplying messages LRRK beneath Parkinson disease. Cell. 157: 291-3. PMID 24725399 DOI: 10.1016/j.cell.2014.03.043  0.64
2014 Shin JY, Dauer WT, Worman HJ. Lamina-associated polypeptide 1: protein interactions and tissue-selective functions. Seminars in Cell & Developmental Biology. 29: 164-8. PMID 24508913 DOI: 10.1016/j.semcdb.2014.01.010  0.64
2014 Bohnen NI, Müller ML, Dauer WT, Albin RL. Parkinsons disease: What role do pedunculopontine cholinergic neurons play? Future Neurology. 9: 5-8. DOI: 10.2217/fnl.13.61  0.64
2014 Dauer W. Inherited Isolated Dystonia: Clinical Genetics and Gene Function Neurotherapeutics. DOI: 10.1007/s13311-014-0297-7  0.64
2013 Santos M, Rebelo S, Van Kleeff PJ, Kim CE, Dauer WT, Fardilha M, da Cruz E Silva OA, da Cruz E Silva EF. The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate. Plos One. 8: e76788. PMID 24116158 DOI: 10.1371/journal.pone.0076788  0.64
2013 Shin JY, Méndez-López I, Wang Y, Hays AP, Tanji K, Lefkowitch JH, Schulze PC, Worman HJ, Dauer WT. Lamina-associated polypeptide-1 interacts with the muscular dystrophy protein emerin and is essential for skeletal muscle maintenance. Developmental Cell. 26: 591-603. PMID 24055652 DOI: 10.1016/j.devcel.2013.08.012  0.64
2013 Ledoux MS, Dauer WT, Warner TT. Emerging common molecular pathways for primary dystonia. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 968-81. PMID 23893453 DOI: 10.1002/mds.25547  0.64
2013 Orenstein SJ, Kuo SH, Tasset I, Arias E, Koga H, Fernandez-Carasa I, Cortes E, Honig LS, Dauer W, Consiglio A, Raya A, Sulzer D, Cuervo AM. Interplay of LRRK2 with chaperone-mediated autophagy. Nature Neuroscience. 16: 394-406. PMID 23455607 DOI: 10.1038/nn.3350  0.64
2012 Albin RL, Dauer WT. Parkinson syndrome. Heterogeneity of etiology; heterogeneity of pathogenesis? Neurology. 79: 202-3. PMID 22722622 DOI: 10.1212/WNL.0b013e31825dd3d0  0.64
2012 Kett LR, Dauer WT. Leucine-rich repeat kinase 2 for beginners: six key questions. Cold Spring Harbor Perspectives in Medicine. 2: a009407. PMID 22393539 DOI: 10.1101/cshperspect.a009407  0.64
2012 Tanabe LM, Martin C, Dauer WT. Genetic background modulates the phenotype of a mouse model of DYT1 dystonia. Plos One. 7: e32245. PMID 22393392 DOI: 10.1371/journal.pone.0032245  0.64
2012 Kett LR, Boassa D, Ho CC, Rideout HJ, Hu J, Terada M, Ellisman M, Dauer WT. LRRK2 Parkinson disease mutations enhance its microtubule association. Human Molecular Genetics. 21: 890-9. PMID 22080837 DOI: 10.1093/hmg/ddr526  0.64
2011 Droggiti A, Ho CC, Stefanis L, Dauer WT, Rideout HJ. Targeted disruption of neuronal 19S proteasome subunits induces the formation of ubiquitinated inclusions in the absence of cell death. Journal of Neurochemistry. 119: 630-43. PMID 21883213 DOI: 10.1111/j.1471-4159.2011.07444.x  0.64
2011 UluÄŸ AM, Vo A, Argyelan M, Tanabe L, Schiffer WK, Dewey S, Dauer WT, Eidelberg D. Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 6638-43. PMID 21464304 DOI: 10.1073/pnas.1016445108  0.64
2011 Martin JN, Wolken N, Brown T, Dauer WT, Ehrlich ME, Gonzalez-Alegre P. Lethal toxicity caused by expression of shRNA in the mouse striatum: implications for therapeutic design. Gene Therapy. 18: 666-73. PMID 21368900 DOI: 10.1038/gt.2011.10  0.64
2010 Dorval T, Ogier A, Genovesio A, Lim HK, Kwon do Y, Lee JH, Worman HJ, Dauer W, Grailhe R. Contextual automated 3D analysis of subcellular organelles adapted to high-content screening. Journal of Biomolecular Screening. 15: 847-57. PMID 20639502 DOI: 10.1177/1087057110374993  0.64
2010 Kim CE, Perez A, Perkins G, Ellisman MH, Dauer WT. A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 9861-6. PMID 20457914 DOI: 10.1073/pnas.0912877107  0.64
2010 Dauer WT, Worman HJ. New messages in the nuclear envelope. Cell Cycle (Georgetown, Tex.). 9: 645-6. PMID 20190576  0.64
2010 Dauer W, Ho CCY. The biology and pathology of the familial Parkinson's disease protein LRRK2 Movement Disorders. 25: S40-S43. PMID 20187256 DOI: 10.1002/mds.22717  0.64
2009 Jorgensen ND, Peng Y, Ho CC, Rideout HJ, Petrey D, Liu P, Dauer WT. The WD40 domain is required for LRRK2 neurotoxicity. Plos One. 4: e8463. PMID 20041156 DOI: 10.1371/journal.pone.0008463  0.64
2009 Dauer WT, Worman HJ. The nuclear envelope as a signaling node in development and disease. Developmental Cell. 17: 626-38. PMID 19922868 DOI: 10.1016/j.devcel.2009.10.016  0.64
2009 Tanabe LM, Kim CE, Alagem N, Dauer WT. Primary dystonia: molecules and mechanisms. Nature Reviews. Neurology. 5: 598-609. PMID 19826400 DOI: 10.1038/nrneurol.2009.160  0.64
2009 Martin JN, Bair TB, Bode N, Dauer WT, Gonzalez-Alegre P. Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia. Neuroscience. 164: 563-72. PMID 19665049 DOI: 10.1016/j.neuroscience.2009.07.068  0.64
2009 Ho CC, Rideout HJ, Ribe E, Troy CM, Dauer WT. The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1011-6. PMID 19176810 DOI: 10.1523/JNEUROSCI.5175-08.2009  0.64
2008 Burke RE, Dauer WT, Vonsattel JP. A critical evaluation of the Braak staging scheme for Parkinson's disease. Annals of Neurology. 64: 485-91. PMID 19067353 DOI: 10.1002/ana.21541  0.64
2008 Zhou C, Huang Y, Shao Y, May J, Prou D, Perier C, Dauer W, Schon EA, Przedborski S. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 105: 12022-7. PMID 18687899 DOI: 10.1073/pnas.0802814105  0.64
2008 Akman HO, Dorado B, López LC, García-Cazorla A, Vilà MR, Tanabe LM, Dauer WT, Bonilla E, Tanji K, Hirano M. Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance. Human Molecular Genetics. 17: 2433-40. PMID 18467430 DOI: 10.1093/hmg/ddn143  0.64
2008 Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, et al. Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. The Journal of Clinical Investigation. 118: 777-88. PMID 18172548 DOI: 10.1172/JCI32806  0.64
2008 Dauer W. Overview: Rodent and fish models of Parkinson's disease Parkinson's Disease. 219-223. DOI: 10.1016/B978-0-12-374028-1.00016-6  0.64
2007 Dauer W. Neurotrophic factors and Parkinson's disease: the emergence of a new player? Science's Stke : Signal Transduction Knowledge Environment. 2007: pe60. PMID 17986711 DOI: 10.1126/stke.4112007pe60  0.64
2007 Cookson MR, Dauer W, Dawson T, Fon EA, Guo M, Shen J. The roles of kinases in familial Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11865-8. PMID 17978026 DOI: 10.1523/JNEUROSCI.3695-07.2007  0.64
2007 Liu S, Fa M, Ninan I, Trinchese F, Dauer W, Arancio O. Alpha-synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGK and CaMKII. The European Journal of Neuroscience. 25: 3583-96. PMID 17610578 DOI: 10.1111/j.1460-9568.2007.05569.x  0.64
2006 Greene PE, Dauer W. Stiff child syndrome with mutation of DYT1 gene [7] Neurology. 66: 1456. PMID 16682692  0.64
2005 Goodchild RE, Kim CE, Dauer WT. Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope. Neuron. 48: 923-32. PMID 16364897 DOI: 10.1016/j.neuron.2005.11.010  0.64
2005 Goodchild RE, Dauer WT. The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein. The Journal of Cell Biology. 168: 855-62. PMID 15767459 DOI: 10.1083/jcb.200411026  0.64
2004 Liu S, Ninan I, Antonova I, Battaglia F, Trinchese F, Narasanna A, Kolodilov N, Dauer W, Hawkins RD, Arancio O. alpha-Synuclein produces a long-lasting increase in neurotransmitter release. The Embo Journal. 23: 4506-16. PMID 15510220 DOI: 10.1038/sj.emboj.7600451  0.64
2004 Stefanis L, Wang Q, Oo T, Lang-Rollin I, Burke RE, Dauer WT. Lack of alpha-synuclein does not alter apoptosis of neonatal catecholaminergic neurons. The European Journal of Neuroscience. 20: 1969-72. PMID 15380020 DOI: 10.1111/j.1460-9568.2004.03638.x  0.64
2004 Rideout HJ, Dietrich P, Wang Q, Dauer WT, Stefanis L. alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons. The Journal of Biological Chemistry. 279: 46915-20. PMID 15322100 DOI: 10.1074/jbc.M405146200  0.64
2004 Kholodilov N, Yarygina O, Oo TF, Zhang H, Sulzer D, Dauer W, Burke RE. Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3136-46. PMID 15044553 DOI: 10.1523/JNEUROSCI.4506-03.2004  0.64
2004 Goodchild RE, Dauer WT. Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation. Proceedings of the National Academy of Sciences of the United States of America. 101: 847-52. PMID 14711988 DOI: 10.1073/pnas.0304375101  0.64
2004 Dauer W, Goodchild R. Mouse models of torsinA dysfunction Advances in Neurology. 94: 67-72. PMID 14509656  0.64
2003 Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron. 39: 889-909. PMID 12971891 DOI: 10.1016/S0896-6273(03)00568-3  0.64
2003 Rideout HJ, Dietrich P, Savalle M, Dauer WT, Stefanis L. Regulation of alpha-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons. Journal of Neurochemistry. 84: 803-13. PMID 12562524 DOI: 10.1046/j.1471-4159.2003.01574.x  0.64
2001 Yamamoto A, Hen R, Dauer WT. The ons and offs of inducible transgenic technology: a review. Neurobiology of Disease. 8: 923-32. PMID 11741388 DOI: 10.1006/nbdi.2001.0452  0.64
1998 Dauer WT, Burke RE, Greene P, Fahn S. Current concepts on the clinical features, aetiology and management of idiopathic cervical dystonia. Brain : a Journal of Neurology. 121: 547-60. PMID 9577384 DOI: 10.1093/brain/121.4.547  0.64
1994 Schwarzschild MA, Dauer WT, Lewis SE, Hamill LK, Fink JS, Hyman SE. Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. Journal of Neurochemistry. 63: 1246-54. PMID 7523587  0.64
1994 Lewis SE, Rao MS, Symes AJ, Dauer WT, Fink JS, Landis SC, Hyman SE. Coordinate regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons. Journal of Neurochemistry. 63: 429-38. PMID 7518494  0.64
1988 Bissette G, Dauer WT, Kilts CD, O'Connor L, Nemeroff CB. The effect of the stereoisomers of butaclamol on neurotensin content in discrete regions of the rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 1: 329-35. PMID 2472151  0.64
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