William T. Dauer - Related publications

Affiliations: 
Columbia University, New York, NY 
Area:
neurology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Wang Z, Dong H, Wang J, Huang Y, Zhang X, Tang Y, Li Q, Liu Z, Ma Y, Tong J, Huang L, Fei J, Yu M, Wang J, Huang F. Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models. Redox Biology. 30: 101427. PMID 31986466 DOI: 10.1016/j.redox.2020.101427   
2020 Sironi L, Restelli LM, Tolnay M, Neutzner A, Frank S. Dysregulated Interorganellar Crosstalk of Mitochondria in the Pathogenesis of Parkinson's Disease. Cells. 9. PMID 31963435 DOI: 10.3390/cells9010233   
2020 Cheng J, Liao Y, Dong Y, Hu H, Yang N, Kong X, Li S, Li X, Guo J, Qin L, Yu J, Ma C, Li J, Li M, Tang B, et al. Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice. Autophagy. 1-13. PMID 32003282 DOI: 10.1080/15548627.2020.1719723   
2020 Bai H, Ding Y, Li X, Kong D, Xin C, Yang XK, Zhang CW, Rong Z, Yao C, Lu S, Ji L, Li L, Huang W. Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy. Neurochemistry International. 104671. PMID 31926197 DOI: 10.1016/j.neuint.2020.104671   
2020 Park JH, Burgess JD, Faroqi AH, DeMeo NN, Fiesel FC, Springer W, Delenclos M, McLean PJ. Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway. Molecular Neurodegeneration. 15: 5. PMID 31931835 DOI: 10.1186/s13024-019-0349-x   
2020 Pajarillo E, Rizor A, Son DS, Aschner M, Lee E. The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity. The Journal of Biological Chemistry. PMID 32001620 DOI: 10.1074/jbc.RA119.011446   
2020 Bragato C, Carra S, Blasevich F, Salerno F, Brix A, Bassi A, Beltrame M, Cotelli F, Maggi L, Mantegazza R, Mora M. Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165662. PMID 31917327 DOI: 10.1016/j.bbadis.2020.165662   
2020 Kim S, Indu Viswanath AN, Park JH, Lee HE, Park AY, Choi JW, Kim HJ, Londhe AM, Jang BK, Lee J, Hwang H, Lim SM, Pae AN, Park KD. Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model. Neuropharmacology. 107989. PMID 32032607 DOI: 10.1016/j.neuropharm.2020.107989   
2020 Fan Z, Pan YT, Zhang ZY, Yang H, Yu SY, Zheng Y, Ma JH, Wang XM. Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson's disease. Journal of Neuroinflammation. 17: 11. PMID 31915018 DOI: 10.1186/s12974-019-1670-6   
2020 Fang X, Ma J, Mu D, Li B, Lian B, Sun C. FGF21 Protects Dopaminergic Neurons in Parkinson's Disease Models Via Repression of Neuroinflammation. Neurotoxicity Research. PMID 31997152 DOI: 10.1007/s12640-019-00151-6   
2020 Evans CS, Holzbaur EL. Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons. Elife. 9. PMID 31934852 DOI: 10.7554/eLife.50260   
2020 Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X. Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice. Behavioural Brain Research. 112539. PMID 32032741 DOI: 10.1016/j.bbr.2020.112539   
2020 Moskal N, Riccio V, Bashkurov M, Taddese R, Datti A, Lewis PN, Angus McQuibban G. ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway. Nature Communications. 11: 88. PMID 31900402 DOI: 10.1038/s41467-019-13781-3   
2020 Wijeyekoon RS, Kronenberg-Versteeg D, Scott KM, Hayat S, Kuan WL, Evans JR, Breen DP, Cummins G, Jones JL, Clatworthy MR, Andres Floto R, Barker RA, Williams-Gray CH. Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson's disease. Brain, Behavior, and Immunity. PMID 32006615 DOI: 10.1016/j.bbi.2020.01.018   
2020 Li L, Qiu H, Liu M, Cai Y. A Network Pharmacology-Based Study of the Molecular Mechanisms of Shaoyao-Gancao Decoction in Treating Parkinson's Disease. Interdisciplinary Sciences, Computational Life Sciences. PMID 32006382 DOI: 10.1007/s12539-020-00359-7   
2020 Liu YM, Cong S, Cheng Z, Hu YX, Lei Y, Zhu LL, Zhao XK, Mu M, Zhang BF, Fan LD, Yu L, Cheng ML. Platycodin D alleviates liver fibrosis and activation of hepatic stellate cells by regulating JNK/c-JUN signal pathway. European Journal of Pharmacology. 172946. PMID 31996320 DOI: 10.1016/j.ejphar.2020.172946   
2020 Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1 Mice. International Journal of Biological Sciences. 16: 284-297. PMID 31929756 DOI: 10.7150/ijbs.38487   
2020 Pushpavathi Selvakumar G, Ejaz Ahmed M, Thangavel R, Kempuraj D, Dubova I, Raikwar SP, Zaheer S, Iyer SS, Zaheer A. A role for glia maturation factor dependent activation of mast cells and microglia in MPTP induced dopamine loss and behavioural deficits in mice. Brain, Behavior, and Immunity. PMID 31982500 DOI: 10.1016/j.bbi.2020.01.013   
2020 Ejlerskov P, Rubinsztein DC, Pocock R. IFNB/interferon-β regulates autophagy via a -TBC1D15-RAB7 pathway. Autophagy. 1-3. PMID 31958036 DOI: 10.1080/15548627.2020.1718384   
2020 Mullin S, Smith L, Lee K, D'Souza G, Woodgate P, Elflein J, Hällqvist J, Toffoli M, Streeter A, Hosking J, Heywood WE, Khengar R, Campbell P, Hehir J, Cable S, et al. Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial. Jama Neurology. PMID 31930374 DOI: 10.1001/jamaneurol.2019.4611   
2020 Lee JJ, Andreazza S, Whitworth AJ. The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models. Scientific Reports. 10: 2693. PMID 32060339 DOI: 10.1038/s41598-020-59647-3   
2020 Rao SP, Sharma N, Kalivendi SV. Embelin averts MPTP-induced dysfunction in mitochondrial bioenergetics and biogenesis via activation of SIRT1. Biochimica Et Biophysica Acta. Bioenergetics. 148157. PMID 31987812 DOI: 10.1016/j.bbabio.2020.148157   
2020 Onoyama T, Takeda Y, Yamashita T, Hamamoto W, Sakamoto Y, Koda H, Kawata S, Matsumoto K, Isomoto H. Programmed cell death-1 inhibitor-related sclerosing cholangitis: A systematic review. World Journal of Gastroenterology. 26: 353-365. PMID 31988594 DOI: 10.3748/wjg.v26.i3.353   
2020 Rango M, Dossi G, Squarcina L, Bonifati C. Brain mitochondrial impairment in early-onset Parkinson's disease with or without PINK1 mutation. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31898835 DOI: 10.1002/mds.27946   
2020 Shrestha N, Tobler K, Uster S, Sigrist-Nagy R, Hierweger MM, Ackermann M. Ovine herpesvirus 2 encodes a previously unrecognized protein, pOv8.25, that targets mitochondria and triggers apoptotic cell death. Journal of Virology. PMID 32024777 DOI: 10.1128/JVI.01536-19   
2020 Verdura S, Cuyàs E, Cortada E, Brunet J, Lopez-Bonet E, Martin-Castillo B, Bosch-Barrera J, Encinar JA, Menendez JA. Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity. Aging. 11. PMID 31901900 DOI: 10.18632/aging.102646   
2020 Wagner M, Skorobogatko Y, Pode-Shakked B, Powell CM, Alhaddad B, Seibt A, Barel O, Heimer G, Hoffmann C, Demmer LA, Perilla-Young Y, Remke M, Wieczorek D, Navaratnarajah T, Lichtner P, et al. Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities. American Journal of Human Genetics. PMID 32004447 DOI: 10.1016/j.ajhg.2020.01.002   
2020 Mathew B, Ruiz P, Pathak V, Suto MJ. Development of novel small molecules for the treatment of ALS. Bioorganic & Medicinal Chemistry Letters. 30: 126950. PMID 31928838 DOI: 10.1016/j.bmcl.2020.126950   
2020 Carling PJ, Mortiboys H, Green C, Mihaylov S, Sandor C, Schwartzentruber A, Taylor R, Wei W, Hastings C, Wong S, Lo C, Evetts S, Clemmens H, Wyles M, Willcox S, et al. Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease. Progress in Neurobiology. 101772. PMID 32058042 DOI: 10.1016/j.pneurobio.2020.101772   
2020 He X, Yang L, Huang R, Lin L, Shen Y, Cheng L, Jin L, Wang S, Zhu R. Activation of CB2R with AM1241 ameliorates neurodegeneration via the Xist/miR-133b-3p/Pitx3 axis. Journal of Cellular Physiology. PMID 31989652 DOI: 10.1002/jcp.29530   
2020 Xu S, Yang Q, Bai J, Tao T, Tang L, Chen Y, Chung CS, Fallon EA, Ayala A. BLOCKADE OF ENDOTHELIAL, BUT NOT EPITHELIAL, CELL EXPRESSION OF PD-L1 FOLLOWING SEVERE SHOCK ATTENUATES THE DEVELOPMENT OF INDIRECT ACUTE LUNG INJURY IN MICE. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31994912 DOI: 10.1152/ajplung.00108.2019   
2020 Ham SJ, Lee D, Yoo H, Jun K, Shin H, Chung J. Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. PMID 32047033 DOI: 10.1073/pnas.1909814117   
2020 Su CJ, Shen Z, Cui RX, Huang Y, Xu DL, Zhao FL, Pan J, Shi AM, Liu T, Yu YL. Thioredoxin-Interacting Protein (TXNIP) Regulates Parkin/PINK1-mediated Mitophagy in Dopaminergic Neurons Under High-glucose Conditions: Implications for Molecular Links Between Parkinson's Disease and Diabetes. Neuroscience Bulletin. PMID 31939095 DOI: 10.1007/s12264-019-00459-5   
2020 Cancela S, Canclini L, Mourglia-Ettlin G, Hernández P, Merlino A. Neuroprotective effects of novel nitrones: In vitro and in silico studies. European Journal of Pharmacology. 172926. PMID 31958456 DOI: 10.1016/j.ejphar.2020.172926   
2020 Draper ACE, Wilson Z, Maile C, Faccenda D, Campanella M, Piercy RJ. Species-specific consequences of an E40K missense mutation in superoxide dismutase 1 (SOD1). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 458-473. PMID 31914665 DOI: 10.1096/fj.201901455R   
2020 Cawley NX, Sojka C, Cougnoux A, Lyons AT, Nicoli ER, Wassif CA, Porter FD. Abnormal LAMP1 glycosylation may play a role in Niemann-Pick disease, type C pathology. Plos One. 15: e0227829. PMID 31999726 DOI: 10.1371/journal.pone.0227829   
2020 Busch LM, Sun J, Cui X, Eichacker PQ, Torabi-Parizi P. Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis. Intensive Care Medicine Experimental. 8: 7. PMID 32020483 DOI: 10.1186/s40635-019-0290-x   
2020 Kwon M, Kim CG, Lee H, Cho H, Kim Y, Lee EC, Choi SJ, Park J, Seo IH, Bogen B, Song IC, Jo DY, Kim JS, Park SH, Choi I, et al. PD-1 blockade reinvigorates bone marrow CD8+ T cells from patients with multiple myeloma in the presence of TGF-b inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31941832 DOI: 10.1158/1078-0432.CCR-19-0267   
2020 Chen S, Guo D, Lei B, Bi J, Yang H. Biglycan protects human neuroblastoma cells from nitric oxide-induced death by inhibiting AMPK-mTOR mediated autophagy and intracellular ROS level. Biotechnology Letters. PMID 31989342 DOI: 10.1007/s10529-020-02818-z   
2020 Yeong J, Zhao Z, Lim JCT, Li H, Thike AA, Koh VCY, Teh BT, Kanesvaran R, Toh CK, Tan PH, Khor LY. PD-L1 expression is an unfavourable prognostic indicator in Asian renal cell carcinomas. Journal of Clinical Pathology. PMID 31980560 DOI: 10.1136/jclinpath-2019-206092   
2020 Zhang C, Rong HM, Li T, Zhai K, Tong ZH. PD-1 Deficiency Promotes Macrophage Activation and Th1/Th17 Response in Pneumonia. American Journal of Respiratory Cell and Molecular Biology. PMID 32048861 DOI: 10.1165/rcmb.2019-0234OC   
2020 Allen EA, Baehrecke EH. Autophagy in animal development. Cell Death and Differentiation. PMID 31988494 DOI: 10.1038/s41418-020-0497-0   
2020 Zou Y, Padmanabhan S, Vancurova I. Analysis of PD-L1 Transcriptional Regulation in Ovarian Cancer Cells by Chromatin Immunoprecipitation. Methods in Molecular Biology (Clifton, N.J.). 2108: 229-239. PMID 31939185 DOI: 10.1007/978-1-0716-0247-8_20   
2020 Hijikata Y, Matsubara Y, Ota Y, Lim LA, Tani K, Hirata Y, Yotsuyanagi H. Safe Use of Nivolumab in a Patient with Epipharyngeal Carcinoma and Preexisting Ulcerative Colitis: A Histologically Proven Case Report. Internal Medicine (Tokyo, Japan). PMID 32009094 DOI: 10.2169/internalmedicine.3901-19   
2020 Kim T, Cha YJ, Chang YS. Correlation of PD-L1 Expression Tested by 22C3 and SP263 in Non-Small Cell Lung Cancer and Its Prognostic Effect on Mutation-Positive Lung Adenocarcinoma. Tuberculosis and Respiratory Diseases. 83: 51-60. PMID 31905432 DOI: 10.4046/trd.2019.0026   
2020 Machado TCG, Guatimosim C, Kangussu LM. The Renin-Angiotensin System in Huntington's disease: Villain or hero? Protein and Peptide Letters. PMID 31933441 DOI: 10.2174/0929866527666200110154523   
2020 Tanaka S, Kushimoto M, Nishizawa T, Takubo M, Mitsuke K, Ikeda J, Fujishiro M, Ogawa K, Tsujino I, Suzuki Y, Abe M. Isolated ACTH deficiency during single-agent pembrolizumab for squamous cell lung carcinoma: a case report. Clinical Diabetes and Endocrinology. 6: 1. PMID 31921440 DOI: 10.1186/s40842-019-0092-9   
2020 Emmer BT, Lascuna PJ, Tang VT, Kotnik EN, Saunders TL, Khoriaty R, Ginsburg D. Murine Surf4 is essential for early embryonic development. Plos One. 15: e0227450. PMID 31978056 DOI: 10.1371/journal.pone.0227450   
2020 Rocco D, Malapelle U, Del Re M, Della Gravara L, Pepe F, Danesi R, Troncone G, Gridelli C. Pharmacodynamics of current and emerging PD-1 and PD-L1 inhibitors for the treatment of non-small cell lung cancer. Expert Opinion On Drug Metabolism & Toxicology. PMID 31978315 DOI: 10.1080/17425255.2020.1721460   
2020 Zhang Y, Li Y, Feng Q, Shao M, Yuan F, Liu F. Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae. Chemosphere. 248: 126009. PMID 32000039 DOI: 10.1016/j.chemosphere.2020.126009