Brian S. Meldrum - Publications

Affiliations: 
King's College London, London, UK 
Area:
Epilepsy, Stroke

278 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 De Sarro G, Russo E, Citraro R, Meldrum BS. Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs. Epilepsy & Behavior : E&B. PMID 26254980 DOI: 10.1016/j.yebeh.2015.06.030  1
2010 Henshall DC, Meldrum BS. Cell death after single and repeated brief seizures Epilepsia. 51: 35. DOI: 10.1111/j.1528-1167.2010.02821.x  1
2007 Meldrum B. Status epilepticus: The past and the future Epilepsia. 48: 33-34. PMID 18329993 DOI: 10.1111/j.1528-1167.2007.01343.x  1
2007 Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 4: 18-61. PMID 17199015 DOI: 10.1016/j.nurt.2006.11.010  1
2003 Moldrich RX, Chapman AG, De Sarro G, Meldrum BS. Glutamate metabotropic receptors as targets for drug therapy in epilepsy. European Journal of Pharmacology. 476: 3-16. PMID 12969743 DOI: 10.1016/S0014-2999(03)02149-6  1
2003 Malas S, Postlethwaite M, Ekonomou A, Whalley B, Nishiguchi S, Wood H, Meldrum B, Constanti A, Episkopou V. Sox1-deficient mice suffer from epilepsy associated with abnormal ventral forebrain development and olfactory cortex hyperexcitability. Neuroscience. 119: 421-32. PMID 12770556 DOI: 10.1016/S0306-4522(03)00158-1  1
2003 Suchak SK, Baloyianni NV, Perkinton MS, Williams RJ, Meldrum BS, Rattray M. The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. Journal of Neurochemistry. 84: 522-32. PMID 12558972 DOI: 10.1046/j.1471-4159.2003.01553.x  1
2002 Kwan P, Sills GJ, Butler E, Gant TW, Meldrum BS, Brodie MJ. Regional expression of multidrug resistance genes in genetically epilepsy-prone rat brain after a single audiogenic seizure. Epilepsia. 43: 1318-23. PMID 12423380 DOI: 10.1046/j.1528-1157.2002.156702.x  1
2002 Cordi AA, Desos P, Ruano E, Al-Badri H, Fugier C, Chapman AG, Meldrum BS, Thomas JY, Roger A, Lestage P. Novel quinolinone-phosphonic acid AMPA antagonists devoid of nephrotoxicity. Farmaco (Società Chimica Italiana : 1989). 57: 787-802. PMID 12420874 DOI: 10.1016/S0014-827X(02)01281-8  1
2002 De Sarro G, Chimirri A, Meldrum BS. Group III mGlu receptor agonists potentiate the anticonvulsant effect of AMPA and NMDA receptor block. European Journal of Pharmacology. 451: 55-61. PMID 12223229 DOI: 10.1016/S0014-2999(02)02004-6  1
2002 Meldrum B. Do preclinical seizure models preselect certain adverse effects of antiepileptic drugs Epilepsy Research. 50: 33-40. PMID 12151115 DOI: 10.1016/S0920-1211(02)00066-9  1
2002 Meldrum BS. Implications for neuroprotective treatments. Progress in Brain Research. 135: 487-95. PMID 12143367 DOI: 10.1016/S0079-6123(02)35046-5  1
2002 Meldrum BS. Concept of activity-induced cell death in epilepsy: historical and contemporary perspectives. Progress in Brain Research. 135: 3-11. PMID 12143350 DOI: 10.1016/S0079-6123(02)35003-9  1
2001 Meldrum BS. Why and when are seizures bad for the brain? Trends in Pharmacological Sciences. 22: 445-6. PMID 11592262 DOI: 10.1016/S0165-6147(00)01813-7  1
2001 Chapman AG, Talebi A, Yip PK, Meldrum BS. Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. European Journal of Pharmacology. 424: 107-13. PMID 11476756 DOI: 10.1016/S0014-2999(01)01013-5  1
2001 Moldrich RX, Jeffrey M, Talebi A, Beart PM, Chapman AG, Meldrum BS. Anti-epileptic activity of group II metabotropic glutamate receptor agonists (--)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (--)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795). Neuropharmacology. 41: 8-18. PMID 11445181 DOI: 10.1016/S0028-3908(01)00044-2  1
2001 Yip PK, Meldrum BS, Rattray M. Elevated levels of group-III metabotropic glutamate receptors in the inferior colliculus of genetically epilepsy-prone rats following intracollicular administration of L-serine-O-phosphate. Journal of Neurochemistry. 78: 13-23. PMID 11432969 DOI: 10.1046/j.1471-4159.2001.00418.x  1
2001 Cash D, Beech JS, Rayne RC, Bath PM, Meldrum BS, Williams SC. Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Research. 905: 91-103. PMID 11423083 DOI: 10.1016/S0006-8993(01)02508-2  1
2001 Moldrich RX, Beart PM, Jane DE, Chapman AG, Meldrum BS. Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology. 40: 732-5. PMID 11311902 DOI: 10.1016/S0028-3908(01)00002-8  1
2001 Moldrich RX, Talebi A, Beart PM, Chapman AG, Meldrum BS. The mGlu(2/3) agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate, is anti- and proconvulsant in DBA/2 mice. Neuroscience Letters. 299: 125-9. PMID 11166954 DOI: 10.1016/S0304-3940(00)01732-8  1
2000 Chapman AG, Nanan K, Williams M, Meldrum BS. Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893). Neuropharmacology. 39: 1567-74. PMID 10854901 DOI: 10.1016/S0028-3908(99)00242-7  1
2000 Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. The Journal of Nutrition. 130: 1007S-15S. PMID 10736372  1
2000 Strong AJ, Smith SE, Whittington DJ, Meldrum BS, Parsons AA, Krupinski J, Hunter AJ, Patel S, Robertson C. Factors influencing the frequency of fluorescence transients as markers of peri-infarct depolarizations in focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 31: 214-22. PMID 10625740  1
2000 Meldrum BS, Chapman AG, Tang E, Keaney K, Patel S, Chadwick A, Hodges H. Cell grafts in epilepsy: Therapeutic prospects and problems Acta Neurologica Scandinavica, Supplement. 102: 46-47.  1
1999 Meldrum BS. Antiepileptic drugs potentiating GABA. Electroencephalography and Clinical Neurophysiology. Supplement. 50: 450-7. PMID 10689493  1
1999 Meldrum BS, Chapman AG. Basic mechanisms of gabitril (tiagabine) and future potential developments. Epilepsia. 40: S2-6. PMID 10612355  1
1999 Chapman AG, Nanan K, Yip P, Meldrum BS. Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S)-4-phosphonophenylglycine. European Journal of Pharmacology. 383: 23-7. PMID 10556677 DOI: 10.1016/S0014-2999(99)00615-9  1
1999 Meldrum BS, Akbar MT, Chapman AG. Glutamate receptors and transporters in genetic and acquired models of epilepsy. Epilepsy Research. 36: 189-204. PMID 10515165 DOI: 10.1016/S0920-1211(99)00051-0  1
1999 Meldrum BS, Chapman AG. Excitatory amino acid receptors and antiepileptic drug development. Advances in Neurology. 79: 965-78. PMID 10514879  1
1999 Klapstein GJ, Meldrum BS, Mody I. Decreased sensitivity to Group III mGluR agonists in the lateral perforant path following kindling. Neuropharmacology. 38: 927-33. PMID 10428411 DOI: 10.1016/S0028-3908(99)00016-7  1
1999 Milward AJ, Meldrum BS, Mellanby JH. Forebrain ischaemia with CA1 cell loss impairs epileptogenesis in the tetanus toxin limbic seizure model. Brain : a Journal of Neurology. 122: 1009-16. PMID 10356055 DOI: 10.1093/brain/122.6.1009  1
1999 Chapman AG, Yip PK, Yap JS, Quinn LP, Tang E, Harris JR, Meldrum BS. Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). European Journal of Pharmacology. 368: 17-24. PMID 10096765 DOI: 10.1016/S0014-2999(99)00014-X  1
1999 Meldrum BS. Commentary Epilepsia. 40: 123-124. DOI: 10.1111/j.1528-1157.1999.tb02001.x  1
1999 Honavar M, Everall IP, Meldrum BS. Relative preservation of GABA(A) receptor β-subunit immunoreactivity in the hippocampus in mesial temporal sclerosis Neuropathology. 19: 395-403. DOI: 10.1046/j.1440-1789.1999.00263.x  1
1999 Meldrum B, Gardiner M. Epilepsy Research: Preface Epilepsy Research. 36: 89. DOI: 10.1016/S0920-1211(99)00042-X  1
1998 Meldrum BS. The glutamate synapse as a therapeutical target: perspectives for the future. Progress in Brain Research. 116: 441-58. PMID 9932394  1
1998 Akbar MT, Rattray M, Williams RJ, Chong NW, Meldrum BS. Reduction of GABA and glutamate transporter messenger RNAs in the severe-seizure genetically epilepsy-prone rat. Neuroscience. 85: 1235-51. PMID 9681960 DOI: 10.1016/S0306-4522(97)00684-2  1
1998 Escott KJ, Beech JS, Haga KK, Williams SC, Meldrum BS, Bath PM. Cerebroprotective effect of the nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl) imidazole and 7-nitro indazole, after transient focal cerebral ischemia in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 281-7. PMID 9498844 DOI: 10.1097/00004647-199803000-00006  1
1997 Meldrum B. Discussion Epilepsia. 38: S57-59. PMID 19909328  1
1997 Meldrum BS. Identification and preclinical testing of novel antiepileptic compounds. Epilepsia. 38: S7-15. PMID 9578540  1
1997 Dalby NO, Thomsen C, Fink-Jensen A, Lundbeck J, Søkilde B, Man CM, Sørensen PO, Meldrum B. Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1 Epilepsy Research. 28: 51-61. PMID 9255599 DOI: 10.1016/S0920-1211(97)00033-8  1
1997 Meldrum BS. First Alfred Meyer Memorial Lecture. Epileptic brain damage: a consequence and a cause of seizures. Neuropathology and Applied Neurobiology. 23: 185-201; discussion . PMID 9223128  1
1997 Tang E, Yip PK, Chapman AG, Jane DE, Meldrum BS. Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats. European Journal of Pharmacology. 327: 109-15. PMID 9200548 DOI: 10.1016/S0014-2999(97)89649-5  1
1997 Akbar MT, Torp R, Danbolt NC, Levy LM, Meldrum BS, Ottersen OP. Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience. 78: 351-9. PMID 9145792 DOI: 10.1016/S0306-4522(96)00570-2  1
1997 Smith SE, Hodges H, Sowinski P, Man CM, Leach MJ, Sinden JD, Gray JA, Meldrum BS. Long-term beneficial effects of BW619C89 on neurological deficit, cognitive deficit and brain damage after middle cerebral artery occlusion in the rat. Neuroscience. 77: 1123-35. PMID 9130792 DOI: 10.1016/S0306-4522(96)00530-1  1
1997 Dürmüller N, Graham JL, Sowinski P, Meldrum BS. The vital dye Evans blue mimics limbic seizures induced by kainate or pilocarpine. Brain Research. 753: 283-90. PMID 9125413 DOI: 10.1016/S0006-8993(97)00032-2  1
1996 Meldrum BS, Dürmüller N. Non-NMDA receptor antagonists and the development of amygdala kindling. Epilepsy Research. Supplement. 12: 283-91. PMID 9302527  1
1996 Chapman AG, Elwes RD, Millan MH, Polkey CE, Meldrum BS. Role of glutamate and aspartate in epileptogenesis; contribution of microdialysis studies in animal and man. Epilepsy Research. Supplement. 12: 239-46. PMID 9302522  1
1996 Meldrum B. Action of established and novel anticonvulsant drugs on the basic mechanisms of epilepsy Epilepsy Research. Supplement. 11: 67-77. PMID 9294729  1
1996 Akbar MT, Rattray M, Powell JF, Meldrum BS. Altered expression of group I metabotropic glutamate receptors in the hippocampus of amygdala-kindled rats. Brain Research. Molecular Brain Research. 43: 105-16. PMID 9037524 DOI: 10.1016/S0169-328X(96)00162-3  1
1996 Chapman AG, Woodburn VL, Woodruff GN, Meldrum BS. Anticonvulsant effect of reduced NMDA receptor expression in audiogenic DBA/2 mice. Epilepsy Research. 26: 25-35. PMID 8985683 DOI: 10.1016/S0920-1211(96)00036-8  1
1996 Leigh PN, Meldrum BS. Excitotoxicity in ALS. Neurology. 47: S221-7. PMID 8959993  1
1996 Meldrum BS. Update on the mechanism of action of antiepileptic drugs. Epilepsia. 37: S4-11. PMID 8941036  1
1996 Smith SE, Man CM, Yip PK, Tang E, Chapman AG, Meldrum BS. Anticonvulsant effects of 7-nitroindazole in rodents with reflex epilepsy may result from L-arginine accumulation or a reduction in nitric oxide or L-citrulline formation. British Journal of Pharmacology. 119: 165-73. PMID 8872370  1
1996 Ghauri M, Chapman AG, Meldrum BS. Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs. Neuroreport. 7: 1469-74. PMID 8856700  1
1996 Meldrum BS. The role of nitric oxide in ischemic damage. Advances in Neurology. 71: 355-63. PMID 8790811  1
1996 Hodges H, Sowinski P, Fleming P, Kershaw TR, Sinden JD, Meldrum BS, Gray JA. Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischaemia in rats. Neuroscience. 72: 959-88. PMID 8735223 DOI: 10.1016/0306-4522(96)00004-8  1
1996 Strong AJ, Harland SP, Meldrum BS, Whittington DJ. The use of in vivo fluorescence image sequences to indicate the occurrence and propagation of transient focal depolarizations in cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 367-77. PMID 8621741 DOI: 10.1097/00004647-199605000-00003  1
1995 Meldrum BS. Neurotransmission in epilepsy. Epilepsia. 36: S30-5. PMID 23057108  1
1995 Smith SE, Meldrum BS. Cerebroprotective effect of lamotrigine after focal ischemia in rats. Stroke; a Journal of Cerebral Circulation. 26: 117-21; discussion 1. PMID 7839380  1
1995 Chapman AG, Dürmüller N, Harrison BL, Baron BM, Parvez N, Meldrum BS. Anticonvulsant activity of a novel NMDA/glycine site antagonist, MDL 104,653, against kindled and sound-induced seizures. European Journal of Pharmacology. 274: 83-8. PMID 7768284 DOI: 10.1016/0014-2999(94)00713-H  1
1995 Meldrum BS. Cytoprotective therapies in stroke. Current Opinion in Neurology. 8: 15-23. PMID 7749511  1
1995 Smith SE, Parvez NS, Chapman AG, Meldrum BS. The gamma-aminobutyric acid uptake inhibitor, tiagabine, is anticonvulsant in two animal models of reflex epilepsy. European Journal of Pharmacology. 273: 259-65. PMID 7737333 DOI: 10.1016/0014-2999(94)00696-5  1
1995 Torp R, Lekieffre D, Levy LM, Haug FM, Danbolt NC, Meldrum BS, Ottersen OP. Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus. Experimental Brain Research. 103: 51-8. PMID 7615037 DOI: 10.1007/BF00241964  1
1995 Meldrum BS. Excitatory amino acid receptors and their role in epilepsy and cerebral ischemia. Annals of the New York Academy of Sciences. 757: 492-505. PMID 7611707 DOI: 10.1111/j.1749-6632.1995.tb17509.x  1
1995 Meldrum B. Taking up GABA again Nature. 376: 122-123. PMID 7603559  1
1995 Millan MH, Chapman AG, Meldrum BS. Dual inhibitory action of enadoline (CI977) on release of amino acids in the rat hippocampus. European Journal of Pharmacology. 279: 75-81. PMID 7556386 DOI: 10.1016/0014-2999(95)00141-7  1
1995 Taylor CP, Meldrum BS. Na+ channels as targets for neuroprotective drugs. Trends in Pharmacological Sciences. 16: 309-16. PMID 7482996 DOI: 10.1016/S0165-6147(00)89060-4  1
1994 Dürmüller N, Craggs M, Meldrum BS. The effect of the non-NMDA receptor antagonist GYKI 52466 and NBQX and the competitive NMDA receptor antagonist D-CPPene on the development of amygdala kindling and on amygdala-kindled seizures. Epilepsy Research. 17: 167-74. PMID 8194512 DOI: 10.1016/0920-1211(94)90016-7  1
1994 Meldrum BS. The role of glutamate in epilepsy and other CNS disorders. Neurology. 44: S14-23. PMID 7970002  1
1994 Pearce PC, Maclean CJ, Shergill HK, Ward EM, Halsey MJ, Tindley G, Pearson J, Meldrum BS. Protection from high pressure induced hyperexcitability by the AMPA/kainate receptor antagonists GYKI 52466 and LY 293558. Neuropharmacology. 33: 605-12. PMID 7936094 DOI: 10.1016/0028-3908(94)90164-3  1
1994 Zeman S, Lloyd C, Meldrum B, Leigh PN. Excitatory amino acids, free radicals and the pathogenesis of motor neuron disease Neuropathology and Applied Neurobiology. 20: 219-231. PMID 7936071  1
1994 Nunn JA, LePeillet E, Netto CA, Hodges H, Gray JA, Meldrum BS. Global ischaemia: hippocampal pathology and spatial deficits in the water maze. Behavioural Brain Research. 62: 41-54. PMID 7917032 DOI: 10.1016/0166-4328(94)90036-1  1
1994 Pearce PC, Halsey MJ, Maclean CJ, Ward EM, Shergill HK, Tindley G, Meldrum BS. Lack of effect of lamotrigine against HPNS in rodent and primate models. Pharmacology, Biochemistry, and Behavior. 48: 259-63. PMID 7913227 DOI: 10.1016/0091-3057(94)90525-8  1
1994 Arvin B, Lekieffre D, Graham JL, Moncada C, Chapman AG, Meldrum BS. Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia. Journal of Neurochemistry. 62: 1458-67. PMID 7907651  1
1994 Millan MH, Chapman AG, Meldrum BS. Contrasting effects of D- and L-(E)-4-(3-phosphono-2-propenyl)piperazine-2-carboxylic acid as anticonvulsants and as inhibitors of potassium-evoked increases in hippocampal extracellular glutamate and aspartate levels in freely moving rats. Journal of Neurochemistry. 62: 217-22. PMID 7903351  1
1994 Meldrum BS. Lamotrigine--a novel approach. Seizure. 3: 41-5. PMID 7894851  1
1994 Willis CL, Meldrum BS, Nunn PB, Anderton BH, Leigh PN. Neuroprotective effect of free radical scavengers on beta-N-oxalylamino-L-alanine (BOAA)-induced neuronal damage in rat hippocampus. Neuroscience Letters. 182: 159-62. PMID 7536312 DOI: 10.1016/0304-3940(94)90787-0  1
1994 Moncada CR, Arvin B, Meldrum BS. The pyrimidine derivative BW 1003C87 protects against excitotoxic lesions induced by kainate in the rat striatum. Neuroscience Letters. 179: 17-20. PMID 7531313 DOI: 10.1016/0304-3940(94)90924-5  1
1993 Netto CA, Hodges H, Sinden JD, Le Peillet E, Kershaw T, Sowinski P, Meldrum BS, Gray JA. Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze. Neuroscience. 54: 69-92. PMID 8515847 DOI: 10.1016/0306-4522(93)90384-R  1
1993 Chapman AG, al-Zubaidy Z, Meldrum BS. Aniracetam reverses the anticonvulsant action of NBQX and GYKI 52466 in DBA/2 mice. European Journal of Pharmacology. 231: 301-3. PMID 8453982 DOI: 10.1016/0014-2999(93)90465-T  1
1993 Chapman AG, Meldrum BS. Excitatory amino acid antagonists and epilepsy. Biochemical Society Transactions. 21: 106-10. PMID 8449271  1
1993 Meldrum B. Amino acids as dietary excitotoxins: A contribution to understanding neurodegenerative disorders Brain Research Reviews. 18: 293-314. PMID 8401596 DOI: 10.1016/0165-0173(93)90014-Q  1
1993 Smith SE, Meldrum BS. Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, NBQX, after focal ischaemia in the rat. Functional Neurology. 8: 43-8. PMID 8330753  1
1993 Meldrum BS. Excitotoxicity and selective neuronal loss in epilepsy. Brain Pathology (Zurich, Switzerland). 3: 405-12. PMID 8293196  1
1993 Jarrard LE, Meldrum BS. Selective excitotoxic pathology in the rat hippocampus. Neuropathology and Applied Neurobiology. 19: 381-9. PMID 8278020  1
1993 Netto CA, Hodges H, Sinden JD, LePeillet E, Kershaw T, Sowinski P, Meldrum BS, Gray JA. Foetal grafts from hippocampal regio superior alleviate ischaemic-induced behavioural deficits. Behavioural Brain Research. 58: 107-12. PMID 8136038 DOI: 10.1016/0166-4328(93)90095-8  1
1993 Smith SE, al-Zubaidy ZA, Chapman AG, Meldrum BS. Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat. Epilepsy Research. 15: 101-11. PMID 8103738 DOI: 10.1016/0920-1211(93)90091-K  1
1993 Meldrum BS. Intracerebral microdialysis and seizure initiation. Lancet. 341: 1627. PMID 8099996 DOI: 10.1016/0140-6736(93)90764-8  1
1993 Millan MH, Chapman AG, Meldrum BS. Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures. Epilepsy Research. 14: 139-48. PMID 8095893 DOI: 10.1016/0920-1211(93)90018-3  1
1993 Torp R, Arvin B, Le Peillet E, Chapman AG, Ottersen OP, Meldrum BS. Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Experimental Brain Research. 96: 365-76. PMID 7905421 DOI: 10.1007/BF00234106  1
1993 Smith SE, Lekieffre D, Sowinski P, Meldrum BS. Cerebroprotective effect of BW619C89 after focal or global cerebral ischaemia in the rat. Neuroreport. 4: 1339-42. PMID 7903166  1
1993 Pearce PC, Halsey MJ, Maclean CJ, Ward EM, Pearson J, Henley M, Meldrum BS. The orally active NMDA receptor antagonist CGP 39551 ameliorates the high pressure neurological syndrome in Papio anubis. Brain Research. 622: 177-84. PMID 7902190 DOI: 10.1016/0006-8993(93)90817-7  1
1993 Lekieffre D, Meldrum BS. The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study. Neuroscience. 56: 93-9. PMID 7901808 DOI: 10.1016/0306-4522(93)90565-W  1
1993 Willis CL, Meldrum BS, Nunn PB, Anderton BH, Leigh PN. Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. Brain Research. 627: 55-62. PMID 7507397 DOI: 10.1016/0006-8993(93)90748-C  1
1993 Meldrum BS. Anti-excitatory amino acid approach in the treatment of neurodegenerative disorders European Neuropsychopharmacology. 3: 184-185. DOI: 10.1016/0924-977X(93)90015-E  1
1992 Arvin B, Le Peillet E, Dürmüller N, Chapman AG, Meldrum BS. Electrolytic lesions of the locus coeruleus or 6-hydroxydopamine lesions of the medial forebrain bundle protect against excitotoxic damage in rat hippocampus. Brain Research. 579: 279-84. PMID 1628215 DOI: 10.1016/0006-8993(92)90061-D  1
1992 Smith SE, Meldrum BS. Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat. Stroke; a Journal of Cerebral Circulation. 23: 861-4. PMID 1595106  1
1992 Smith SE, Meldrum BS. The glycine-site NMDA receptor antagonist, R-(+)-cis-beta-methyl-3-amino-1-hydroxypyrrolid-2-one, L-687,414 is anticonvulsant in baboons. European Journal of Pharmacology. 211: 109-11. PMID 1535595 DOI: 10.1016/0014-2999(92)90270-E  1
1992 Smith SE, Meldrum BS. The protein kinase C activators, phorbol 12-myristate,13-acetate and phorbol 12,13-dibutyrate, are convulsant in the pico-nanomolar range in mice. European Journal of Pharmacology. 213: 133-5. PMID 1499648 DOI: 10.1016/0014-2999(92)90242-V  1
1992 Meldrum BS, Swan JH, Leach MJ, Millan MH, Gwinn R, Kadota K, Graham SH, Chen J, Simon RP. Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87. Brain Research. 593: 1-6. PMID 1458310 DOI: 10.1016/0006-8993(92)91254-C  1
1992 White HS, Patel S, Meldrum BS. Anticonvulsant profile of MDL 27,266: an orally active, broad-spectrum anticonvulsant agent. Epilepsy Research. 12: 217-26. PMID 1396547 DOI: 10.1016/0920-1211(92)90076-6  1
1992 Baron BM, Harrison BL, McDonald IA, Meldrum BS, Palfreyman MG, Salituro FG, Siegel BW, Slone AL, Turner JP, White HS. Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site. The Journal of Pharmacology and Experimental Therapeutics. 262: 947-56. PMID 1388205  1
1992 Pearce PC, Halsey MJ, MacLean CJ, Passingham S, Pearson J, Mehta RL, Meldrum BS, Jordan CJ, Ward EM. Interactions of the beta carboline abecarnil with the high pressure neurological syndrome in a primate model. Psychopharmacology. 109: 163-71. PMID 1365651 DOI: 10.1007/BF02245495  1
1992 De Sarro G, Meldrum BS, De Sarro A, Patel S. Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine. Brain Research. 591: 209-22. PMID 1359921 DOI: 10.1016/0006-8993(92)91701-F  1
1992 Arvin B, Moncada C, Le Peillet E, Chapman A, Meldrum BS. GYKI 52466 blocks the increase in extracellular glutamate induced by ischaemia. Neuroreport. 3: 235-8. PMID 1355369  1
1992 Le Peillet E, Arvin B, Moncada C, Meldrum BS. The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat. Brain Research. 571: 115-20. PMID 1351775 DOI: 10.1016/0006-8993(92)90516-C  1
1992 Meldrum BS. Novel antiepileptic drugs. Relations with neurotransmitter mechanisms underlying frontal epilepsies. Advances in Neurology. 57: 635-41. PMID 1347436  1
1992 Meldrum BS, Craggs MD, Dürmüller N, Smith SE, Chapman AG. The effects of AMPA receptor antagonists on kindled seizures and on reflex epilepsy in rodents and primates. Epilepsy Research. Supplement. 9: 307-11. PMID 1337444  1
1992 Meldrum BS. Excitatory amino acids in epilepsy and potential novel therapies. Epilepsy Research. 12: 189-96. PMID 1327746 DOI: 10.1016/0920-1211(92)90040-Z  1
1992 Meldrum BS. Excitatory amino acid receptors and disease. Current Opinion in Neurology and Neurosurgery. 5: 508-13. PMID 1325224  1
1992 Leppik IE, Loscher W, MacDonald RL, Schmidt D, Meldrum BS. Editorial Epilepsy Research. 11: 1. DOI: 10.1016/0920-1211(92)90014-K  1
1992 Hodges H, Sinden JD, Netto CA, Xavier GF, Kershaw TR, Sowinski P, Meldrum BS, Gray JA. Graft-Induced recovery of cognitive function after diffuse or focal brain damage Journal of Neural Transplantation and Plasticity. 3: 173-174.  1
1991 De Sarro G, De Sarro A, Meldrum BS. Anticonvulsant action of 2-chloroadenosine injected focally into the inferior colliculus and substantia nigra. European Journal of Pharmacology. 194: 145-52. PMID 2060598 DOI: 10.1016/0014-2999(91)90098-B  1
1991 Millan MH, Wardley-Smith B, Dürmüller N, Meldrum BS. The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate. Experimental Neurology. 112: 317-20. PMID 2029931 DOI: 10.1016/0014-4886(91)90133-W  1
1991 Pearce PC, Halsey MJ, MacLean CJ, Ward EM, Webster MT, Luff NP, Pearson J, Charlett A, Meldrum BS. The effects of the competitive NMDA receptor antagonist CPP on the high pressure neurological syndrome in a primate model. Neuropharmacology. 30: 787-96. PMID 1833661 DOI: 10.1016/0028-3908(91)90187-G  1
1991 Moncada C, Arvin B, Le Peillet E, Meldrum BS. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience Letters. 133: 287-90. PMID 1816508 DOI: 10.1016/0304-3940(91)90590-P  1
1991 Turner JP, Meldrum BS. L-glutamate diethyl ester and deaminated analogues as excitatory amino acid antagonists in rat cerebral cortex. British Journal of Pharmacology. 104: 445-51. PMID 1797311  1
1991 Chapman AG, Smith SE, Meldrum BS. The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice. Epilepsy Research. 9: 92-6. PMID 1794356 DOI: 10.1016/0920-1211(91)90018-B  1
1991 Millan MH, Obrenovitch TP, Sarna GS, Lok SY, Symon L, Meldrum BS. Changes in rat brain extracellular glutamate concentration during seizures induced by systemic picrotoxin or focal bicuculline injection: an in vivo dialysis study with on-line enzymatic detection. Epilepsy Research. 9: 86-91. PMID 1794355 DOI: 10.1016/0920-1211(91)90017-A  1
1991 Vasar E, Stephenson JD, Meldrum BS. Changes in motor activity and forebrain [propionyl-3H]propionylated-CCK-8 binding in mice after repeated administration of drugs affecting cholecystokinin receptors. European Journal of Pharmacology. 202: 385-90. PMID 1748160 DOI: 10.1016/0014-2999(91)90283-V  1
1991 Meldrum BS. Excitatory amino acid transmitters in epilepsy. Epilepsia. 32: S1-3. PMID 1723042  1
1991 Smith SE, Dürmüller N, Meldrum BS. The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy. European Journal of Pharmacology. 201: 179-83. PMID 1686756 DOI: 10.1016/0014-2999(91)90342-N  1
1991 Millan MH, Wardley-Smith B, Halsey MJ, Meldrum BS. Brain nuclei and neurotransmitters involved in the regulation of the high pressure neurological syndrome in the rat. Neuropharmacology. 30: 1351-5. PMID 1686303 DOI: 10.1016/0028-3908(91)90033-8  1
1991 Chapman AG, Graham JL, Patel S, Meldrum BS. Anticonvulsant activity of two orally active competitive N-methyl-D-aspartate antagonists, CGP 37849 and CGP 39551, against sound-induced seizures in DBA/2 mice and photically induced myoclonus in Papio papio. Epilepsia. 32: 578-87. PMID 1678345  1
1991 Meldrum BS. Neurochemical substrates of ictal behavior. Advances in Neurology. 55: 35-45. PMID 1672238  1
1990 Chapman AG, Graham J, Meldrum BS. Potent oral anticonvulsant action of CPP and CPPene in DBA/2 mice. European Journal of Pharmacology. 178: 97-9. PMID 2332032 DOI: 10.1016/0014-2999(90)94798-3  1
1990 Patel S, Chapman AG, Graham JL, Meldrum BS, Frey P. Anticonvulsant activity of the NMDA antagonists, D(-)4-(3-phosphonopropyl) piperazine-2-carboxylic acid (D-CPP) and D(-)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent and a primate model of reflex epilepsy. Epilepsy Research. 7: 3-10. PMID 2292244 DOI: 10.1016/0920-1211(90)90049-2  1
1990 De Sarro G, De Sarro A, Federico F, Meldrum BS. Anticonvulsant properties of some calcium antagonists on sound-induced seizures in genetically epilepsy prone rats. General Pharmacology. 21: 769-78. PMID 2276595 DOI: 10.1016/0306-3623(90)91032-M  1
1990 Pearce PC, Doré CJ, Halsey MJ, Luff NP, Maclean CJ, Meldrum BS. The effects of MK801 on the high pressure neurological syndrome in the baboon (Papio anubis). Neuropharmacology. 29: 931-41. PMID 2255385 DOI: 10.1016/0028-3908(90)90144-G  1
1990 Fine A, Meldrum BS, Patel S. Modulation of experimentally induced epilepsy by intracerebral grafts of fetal GABAergic neurons. Neuropsychologia. 28: 627-34. PMID 2168529 DOI: 10.1016/0028-3932(90)90038-P  1
1990 Millan MH, Wardley-Smith B, Halsey MJ, Meldrum BS. Effect of NMDA and 2-amino-7-phosphonoheptanoate focal injection into the ventrolateral thalamic nucleus on the high pressure neurological syndrome in the rat. Brain Research. 507: 354-6. PMID 2159822 DOI: 10.1016/0006-8993(90)90298-P  1
1990 Swan JH, Meldrum BS. Protection by NMDA antagonists against selective cell loss following transient ischaemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 10: 343-51. PMID 2158499 DOI: 10.1038/jcbfm.1990.63  1
1990 Smith SE, Meldrum BS. Receptor site specificity for the acute effects of beta-N-methylamino-alanine in mice. European Journal of Pharmacology. 187: 131-4. PMID 1980247 DOI: 10.1016/0014-2999(90)90350-F  1
1990 Zhang N, Walberg F, Laake JH, Meldrum BS, Ottersen OP. Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: a light microscopic and semiquantitative electron microscopic study in rat and baboon (Papio anubis). Neuroscience. 38: 61-80. PMID 1979432 DOI: 10.1016/0306-4522(90)90374-D  1
1990 Adamson P, Hajimohammadreza I, Brammer MJ, Campbell IC, Meldrum BS. Presynaptic glutamate/quisqualate receptors: effects on synaptosomal free calcium concentrations. Journal of Neurochemistry. 55: 1850-4. PMID 1977884 DOI: 10.1111/j.1471-4159.1990.tb05767.x  1
1990 Meldrum BS. Anatomy, physiology, and pathology of epilepsy. Lancet. 336: 231-4. PMID 1973782 DOI: 10.1016/0140-6736(90)91747-X  1
1990 Turski L, Stephens DN, Jensen LH, Petersen EN, Meldrum BS, Patel S, Hansen JB, Löscher W, Schneider HH, Schmiechen R. Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio. The Journal of Pharmacology and Experimental Therapeutics. 253: 344-52. PMID 1970362  1
1989 Chapman AG, Meldrum BS. Non-competitive N-methyl-D-aspartate antagonists protect against sound-induced seizures in DBA/2 mice. European Journal of Pharmacology. 166: 201-11. PMID 2676564 DOI: 10.1016/0014-2999(89)90060-5  1
1989 Meldrum BS. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. British Journal of Clinical Pharmacology. 27: 3S-11S. PMID 2667605  1
1989 Faingold CL, Millan MH, Boersma Anderson CA, Meldrum BS. Induction of audiogenic seizures in normal and genetically epilepsy-prone rats following focal microinjection of an excitant amino acid into reticular formation and auditory nuclei. Epilepsy Research. 3: 199-205. PMID 2659321 DOI: 10.1016/0920-1211(89)90024-7  1
1989 Geddes JW, Cooper SM, Cotman CW, Patel S, Meldrum BS. N-methyl-D-aspartate receptors in the cortex and hippocampus of baboon (Papio anubis and Papio papio). Neuroscience. 32: 39-47. PMID 2573860 DOI: 10.1016/0306-4522(89)90106-1  1
1989 Millan MH, Wardley-Smith B, Halsey MJ, Meldrum BS. Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats. Experimental Brain Research. 78: 174-8. PMID 2556289 DOI: 10.1007/BF00230696  1
1989 Chapman AG, Dürmuller N, Lees GJ, Meldrum BS. Excitotoxicity of NMDA and kainic acid is modulated by nigrostriatal dopaminergic fibres. Neuroscience Letters. 107: 256-60. PMID 2515501 DOI: 10.1016/0304-3940(89)90827-6  1
1989 Meldrum BS, Nanji N, Cornell RG. Lack of effect of aspartame or of L-phenylalanine on photically induced myoclonus in the baboon, Papio papio. Epilepsy Research. 4: 1-7. PMID 2502388 DOI: 10.1016/0920-1211(89)90051-X  1
1989 Meldrum BS. Excitatory amino acid in epilepsy and the potential use of antagonist agents New Trends in Clinical Neuropharmacology. 3: 112.  1
1988 De Sarro GB, Meldrum BS, Nisticó G. Anticonvulsant effects of some calcium entry blockers in DBA/2 mice. British Journal of Pharmacology. 93: 247-56. PMID 3359104  1
1988 Millan MH, Meldrum BS, Boersma CA, Faingold CL. Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. II. Efferent seizure propagating pathway. Experimental Neurology. 99: 687-98. PMID 3342851 DOI: 10.1016/0014-4886(88)90185-9  1
1988 Faingold CL, Millan MH, Boersma CA, Meldrum BS. Excitant amino acids and audiogenic seizures in the genetically epilepsy-prone rat. I. Afferent seizure initiation pathway. Experimental Neurology. 99: 678-86. PMID 3342850 DOI: 10.1016/0014-4886(88)90184-7  1
1988 Patel S, Meldrum BS, Fine A. Susceptibility to pilocarpine-induced seizures in rats increases with age. Behavioural Brain Research. 31: 165-7. PMID 3202947 DOI: 10.1016/0166-4328(88)90019-8  1
1988 Patel S, De Sarro GB, Meldrum BS. Regulation of seizure threshold by excitatory amino acids in the striatum and entopeduncular nucleus of rats. Neuroscience. 27: 837-50. PMID 3075270 DOI: 10.1016/0306-4522(88)90187-X  1
1988 Kerwin RW, Patel S, Meldrum BS, Czudek C, Reynolds GP. Asymmetrical loss of glutamate receptor subtype in left hippocampus in schizophrenia. Lancet. 1: 583-4. PMID 2894510 DOI: 10.1016/S0140-6736(88)91371-2  1
1988 Millan MH, Patel S, Meldrum BS. The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats. Experimental Brain Research. 72: 517-22. PMID 2853076 DOI: 10.1007/BF00250597  1
1988 Lehmann J, Chapman AG, Meldrum BS, Hutchison A, Tsai C, Wood PL. CGS 19755 is a potent and competitive antagonist at NMDA-type receptors. European Journal of Pharmacology. 154: 89-93. PMID 2846329 DOI: 10.1016/0014-2999(88)90368-8  1
1988 Patel S, Millan MH, Meldrum BS. Decrease in excitatory transmission within the lateral habenula and the mediodorsal thalamus protects against limbic seizures in rats. Experimental Neurology. 101: 63-74. PMID 2839355 DOI: 10.1016/0014-4886(88)90065-9  1
1988 Swan JH, Evans MC, Meldrum BS. Long-term development of selective neuronal loss and the mechanism of protection by 2-amino-7-phosphonoheptanoate in a rat model of incomplete forebrain ischaemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 8: 64-78. PMID 2828386 DOI: 10.1038/jcbfm.1988.9  1
1988 Meldrum BS. Excitatory amino acids in neurological disease Current Opinion in Neurology and Neurosurgery. 1: 563-568.  1
1987 Meldrum BS, Kerwin RW. Glutamate receptors and schizophrenia. Journal of Psychopharmacology (Oxford, England). 1: 217-21. PMID 22159133 DOI: 10.1177/026988118700100401  1
1987 Turski L, Meldrum BS, Cavalheiro EA, Calderazzo-Filho LS, Bortolotto ZA, Ikonomidou-Turski C, Turski WA. Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen. Proceedings of the National Academy of Sciences of the United States of America. 84: 1689-93. PMID 3550795 DOI: 10.1073/pnas.84.6.1689  1
1987 Turski L, Klockgether T, Schwarz M, Sontag KH, Meldrum BS. Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents. Neuroscience. 20: 285-92. PMID 3550520 DOI: 10.1016/0306-4522(87)90020-0  1
1987 Falch E, Meldrum BS, Krogsgaard-Larsen P. GABA uptake inhibitors. Synthesis and effects on audiogenic seizures of ester prodrugs of nipecotic acid, guvacine and cis-4-hydroxynipecotic acid. Drug Design and Delivery. 2: 9-21. PMID 3509345  1
1987 Evans MC, Swan JH, Meldrum BS. An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus. Neuroscience Letters. 83: 287-92. PMID 3441311 DOI: 10.1016/0304-3940(87)90101-7  1
1987 Germano IM, Pitts LH, Meldrum BS, Bartkowski HM, Simon RP. Kynurenate inhibition of cell excitation decreases stroke size and deficits. Annals of Neurology. 22: 730-4. PMID 3435082 DOI: 10.1002/ana.410220609  1
1987 Chapman AG, Engelsen B, Meldrum BS. 2-Amino-7-phosphonoheptanoic acid inhibits insulin-induced convulsions and striatal aspartate accumulation in rats with frontal cortical ablation. Journal of Neurochemistry. 49: 121-7. PMID 3295120  1
1987 Chapman AG, De Sarro GB, Premachandra M, Meldrum BS. Bidirectional effects of beta-carbolines in reflex epilepsy. Brain Research Bulletin. 19: 337-46. PMID 3119161 DOI: 10.1016/0361-9230(87)90102-X  1
1987 Wardley-Smith B, Meldrum BS, Halsey MJ. The effect of two novel dipeptide antagonists of excitatory amino acid neurotransmission on the high pressure neurological syndrome in the rat. European Journal of Pharmacology. 138: 417-20. PMID 3040442 DOI: 10.1016/0014-2999(87)90481-X  1
1987 Turski L, Meldrum BS, Turski WA, Watkins JC. Evidence that antagonism at non-NMDA receptors results in anticonvulsant action. European Journal of Pharmacology. 136: 69-73. PMID 3036544 DOI: 10.1016/0014-2999(87)90780-1  1
1987 Patel S, Millan MH, Meldrum BS. Neurotransmission in the pedunculopontine nucleus and pilocarpine-induced motor limbic seizures in rats. Neuroscience Letters. 74: 243-9. PMID 3033555 DOI: 10.1016/0304-3940(87)90157-1  1
1987 Meldrum BS, Evans MC, Swan JH, Simon RP. Protection against hypoxic/ischaemic brain damage with excitatory amino acid antagonists. Medical Biology. 65: 153-7. PMID 2888931  1
1987 Meldrum BS, Swan JH, Ottersen OP, Storm-Mathisen J. Redistribution of transmitter amino acids in rat hippocampus and cerebellum during seizures induced by L-allylglycine and bicuculline: an immunocytochemical study with antisera against conjugated GABA, glutamate and aspartate. Neuroscience. 22: 17-27. PMID 2888043 DOI: 10.1016/0306-4522(87)90194-1  1
1986 Chapman AG, Faingold CL, Hart GP, Bowker HM, Meldrum BS. Brain regional amino acid levels in seizure susceptible rats: Changes related to sound-induced seizures. Neurochemistry International. 8: 273-9. PMID 20493057 DOI: 10.1016/0197-0186(86)90174-9  1
1986 Meldrum BS, Turski L, Schwarz M, Czuczwar SJ, Sontag KH. Anticonvulsant action of 1,3-dimethyl-5-aminoadamantane. Pharmacological studies in rodents and baboon, Papio papio. Naunyn-Schmiedeberg's Archives of Pharmacology. 332: 93-7. PMID 3951570 DOI: 10.1007/BF00633204  1
1986 Naquet R, Meldrum BS. Myoclonus induced by intermittent light stimulation in the baboon: neurophysiological and neuropharmacological approaches. Advances in Neurology. 43: 611-27. PMID 3946120  1
1986 De Sarro G, Patel S, Meldrum BS. Anticonvulsant action of a kainate antagonist gamma-D-glutamyl aminomethylsulphonic acid injected focally into the substantia nigra and entopeduncular nucleus. European Journal of Pharmacology. 132: 229-36. PMID 3816977 DOI: 10.1016/0014-2999(86)90609-6  1
1986 Millan MH, Patel S, Meldrum BS. Olfactory bulbectomy protects against pilocarpine-induced motor limbic seizures in rats. Brain Research. 398: 204-6. PMID 3801895 DOI: 10.1016/0006-8993(86)91271-0  1
1986 Simon RP, Schmidley JW, Meldrum BS, Swan JH, Chapman AG. Excitatory amino acid and calcium content of subarachnoid spinal fluid during hypoglycemia in the rat. Neuroscience Letters. 71: 370-4. PMID 3796895 DOI: 10.1016/0304-3940(86)90650-6  1
1986 Patel S, Meldrum BS, Collins JF. Distribution of [3H]kainic acid and binding sites in the rat brain: in vivo and in vitro receptor autoradiography. Neuroscience Letters. 70: 301-7. PMID 3774232 DOI: 10.1016/0304-3940(86)90569-0  1
1986 Millan MH, Patel S, Mello LM, Meldrum BS. Focal injection of 2-amino-7-phosphonoheptanoic acid into prepiriform cortex protects against pilocarpine-induced limbic seizures in rats. Neuroscience Letters. 70: 69-74. PMID 3774222 DOI: 10.1016/0304-3940(86)90439-8  1
1986 Swan JH, Meldrum BS, Simon RP. Hyperglycemia does not augment neuronal damage in experimental status epilepticus. Neurology. 36: 1351-4. PMID 3762942  1
1986 Wardley-Smith B, Rostain JC, Meldrum BS, Halsey MJ. Effect of 2-aminophosphonoheptanoic acid on the EEG of rats exposed to high pressure. Undersea Biomedical Research. 13: 155-63. PMID 3727181  1
1986 Chapman AG, Halsey MJ, Hart GP, Luff NP, Meldrum BS, Wardley-Smith B. Regional amino acid concentration in the brains of rats exposed to high pressures. Journal of Neurochemistry. 47: 314-7. PMID 3711908  1
1986 Meldrum BS. Cell damage in epilepsy and the role of calcium in cytotoxicity. Advances in Neurology. 44: 849-55. PMID 3706026  1
1986 Simon RP, Schmidley JW, Swan JH, Meldrum BS. Neuronal alterations in hippocampus following severe hypoglycaemia: a light microscopic and ultrastructural study in the rat. Neuropathology and Applied Neurobiology. 12: 11-26. PMID 3703153  1
1986 Millan MH, Meldrum BS, Faingold CL. Induction of audiogenic seizure susceptibility by focal infusion of excitant amino acid or bicuculline into the inferior colliculus of normal rats. Experimental Neurology. 91: 634-9. PMID 3512285 DOI: 10.1016/0014-4886(86)90059-2  1
1986 De Sarro GB, Nistico G, Meldrum BS. Anticonvulsant properties of flunarizine on reflex and generalized models of epilepsy. Neuropharmacology. 25: 695-701. PMID 3092126 DOI: 10.1016/0028-3908(86)90084-5  1
1986 Meldrum BS. Neuropathological consequences of chemically and electrically induced seizures. Annals of the New York Academy of Sciences. 462: 186-93. PMID 3085568  1
1986 Simon RP, Schmidley JW, Meldrum BS, Swan JH, Chapman AG. Excitotoxic mechanisms in hypoglycaemic hippocampal injury. Neuropathology and Applied Neurobiology. 12: 567-76. PMID 3031525  1
1986 Meldrum BS, Chapman AG. Benzodiazepine receptors and their relationship to the treatment of epilepsy. Epilepsia. 27: S3-13. PMID 3017690  1
1986 Turski L, Cavalheiro EA, Turski WA, Meldrum BS. Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate. Neuroscience. 18: 61-77. PMID 3016600 DOI: 10.1016/0306-4522(86)90179-X  1
1986 Patel S, Millan MH, Mello LM, Meldrum BS. 2-Amino-7-phosphonoheptanoic acid (2-APH) infusion into entopeduncular nucleus protects against limbic seizures in rats. Neuroscience Letters. 64: 226-30. PMID 3008043 DOI: 10.1016/0304-3940(86)90105-9  1
1986 Stephens DN, Meldrum BS, Weidmann R, Schneider C, Grützner M. Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity? Psychopharmacology. 90: 166-9. PMID 2878456 DOI: 10.1007/BF00181234  1
1986 Meldrum BS. Drugs acting on amino acid neurotransmitters. Advances in Neurology. 43: 687-706. PMID 2868623  1
1985 Chapman AG, Hart GP, Meldrum BS, Turski L, Watkins JC. Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity. Neuroscience Letters. 55: 325-30. PMID 3892372 DOI: 10.1016/0304-3940(85)90456-2  1
1985 McWilliam JR, Meldrum BS. Plasma growth hormone responses to microinfusion of noradrenergic agents into or electrical stimulation of the hypothalamus and amygdala in baboons. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 17: 443-7. PMID 2995219 DOI: 10.1055/s-2007-1013572  1
1985 Turski L, Meldrum BS, Jones AW, Watkins JC. Anticonvulsant action of stereoisomers of gamma-glutamylaminomethylsulphonic acid in mice. European Journal of Pharmacology. 111: 279-83. PMID 2990954 DOI: 10.1016/0014-2999(85)90769-1  1
1985 Chapman AG, Cheetham SC, Hart GP, Meldrum BS, Westerberg E. Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents. Journal of Neurochemistry. 45: 370-81. PMID 2861248 DOI: 10.1111/j.1471-4159.1985.tb03998.x  1
1985 Turski L, Meldrum BS, Collins JF. Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist? Brain Research. 336: 162-6. PMID 2860949 DOI: 10.1016/0006-8993(85)90429-9  1
1985 Rostain JC, Wardley-Smith B, Meldrum BS. Effects of 2-amino-7-phosphonoheptanoic acid on EEG of rats. Electroencephalography and Clinical Neurophysiology. 60: 367-9. PMID 2579803 DOI: 10.1016/0013-4694(85)90010-0  1
1985 Ottersen OP, Madsen S, Meldrum BS, Storm-Mathisen J. Taurine in the hippocampal formation of the Senegalese baboon, Papio papio: an immunocytochemical study with an antiserum against conjugated taurine. Experimental Brain Research. 59: 457-62. PMID 2411586 DOI: 10.1007/BF00261334  1
1984 Croucher MJ, Meldrum BS, Collins JF. Anticonvulsant and proconvulsant properties of a series of structural isomers of piperidine dicarboxylic acid. Neuropharmacology. 23: 467-72. PMID 6728132 DOI: 10.1016/0028-3908(84)90257-0  1
1984 Evans MC, Meldrum BS. Regional brain glucose metabolism in chemically-induced seizures in the rat. Brain Research. 297: 235-45. PMID 6722542 DOI: 10.1016/0006-8993(84)90565-1  1
1984 Chapman AG, Croucher MJ, Meldrum BS. Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures. Arzneimittel-Forschung. 34: 1261-4. PMID 6542784  1
1984 De Sarro G, Meldrum BS, Reavill C. Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra. European Journal of Pharmacology. 106: 175-9. PMID 6529964 DOI: 10.1016/0014-2999(84)90692-7  1
1984 Collins JF, Dixon AJ, Badman G, De Sarro G, Chapman AG, Hart GP, Meldrum BS. Kainic acid derivatives with anticonvulsant activity. Neuroscience Letters. 51: 371-6. PMID 6521964 DOI: 10.1016/0304-3940(84)90405-1  1
1984 Evans MC, Griffiths T, Meldrum BS. Kainic acid seizures and the reversibility of calcium loading in vulnerable neurons in the hippocampus. Neuropathology and Applied Neurobiology. 10: 285-302. PMID 6483108  1
1984 Simon RP, Griffiths T, Evans MC, Swan JH, Meldrum BS. Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 4: 350-61. PMID 6470053 DOI: 10.1038/jcbfm.1984.52  1
1984 Griffiths T, Evans MC, Meldrum BS. Status epilepticus: the reversibility of calcium loading and acute neuronal pathological changes in the rat hippocampus. Neuroscience. 12: 557-67. PMID 6462462 DOI: 10.1016/0306-4522(84)90073-3  1
1984 Chapman AG, Croucher MJ, Meldrum BS. Anticonvulsant activity of intracerebroventricularly administered valproate and valproate analogues. A dose-dependent correlation with changes in brain aspartate and GABA levels in DBA/2 mice. Biochemical Pharmacology. 33: 1459-63. PMID 6428419 DOI: 10.1016/0006-2952(84)90413-1  1
1984 De Sarro GB, Croucher MJ, Meldrum BS. Anticonvulsant actions of DS 103-282. Pharmacological studies in rodents and the baboon, Papio papio. Neuropharmacology. 23: 525-30. PMID 6377114 DOI: 10.1016/0028-3908(84)90025-X  1
1984 Wardley-Smith B, Meldrum BS, Halsey MJ. The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. Neuroscience Letters. 48: 155-60. PMID 6148724 DOI: 10.1016/0304-3940(84)90012-0  1
1984 Jones AW, Croucher MJ, Meldrum BS, Watkins JC. Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists. Neuroscience Letters. 45: 157-61. PMID 6145126 DOI: 10.1016/0304-3940(84)90092-2  1
1984 Croucher MJ, Meldrum BS, Jones AW, Watkins JC. gamma-D-Glutamylaminomethylsulphonic acid (GAMS), a kainate and quisqualate antagonist, prevents sound-induced seizures in DBA/2 mice. Brain Research. 322: 111-4. PMID 6097331 DOI: 10.1016/0006-8993(84)91186-7  1
1984 Wardley-Smith B, Meldrum BS. Effect of excitatory amino acid antagonists on the high pressure neurological syndrome in rats. European Journal of Pharmacology. 105: 351-4. PMID 6096158 DOI: 10.1016/0014-2999(84)90631-9  1
1984 Simon RP, Swan JH, Griffiths T, Meldrum BS. Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science (New York, N.Y.). 226: 850-2. PMID 6093256  1
1983 Kerwin RW, Meldrum BS. Effect on cerebral D-[3H]aspartate release of 3-mercaptopropionic acid and methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate. European Journal of Pharmacology. 89: 265-9. PMID 6873162 DOI: 10.1016/0014-2999(83)90503-4  1
1983 Croucher MJ, Meldrum BS, Krogsgaard-Larsen P. Anticonvulsant activity of GABA uptake inhibitors and their prodrugs following central or systemic administration. European Journal of Pharmacology. 89: 217-28. PMID 6873158 DOI: 10.1016/0014-2999(83)90497-1  1
1983 Meldrum BS, Murugaiah K. Anticonvulsant action in mice with sound-induced seizures of the optical isomers of gamma-vinyl GABA. European Journal of Pharmacology. 89: 149-52. PMID 6861883  0.84
1983 Griffiths T, Evans MC, Meldrum BS. Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline or L-allylglycine. Neuroscience. 10: 385-95. PMID 6633867 DOI: 10.1016/0306-4522(83)90141-0  1
1983 Anlezark GM, Blackwood DH, Meldrum BS, Ram VJ, Neumeyer JL. Comparative assessment of dopamine agonist aporphines as anticonvulsants in two models of reflex epilepsy. Psychopharmacology. 81: 135-9. PMID 6415743 DOI: 10.1007/BF00429007  1
1983 Meldrum BS, Evans MC, Braestrup C. Anticonvulsant action in the photosensitive baboon, Papio papio, of a novel beta-carboline derivative, ZK 91296. European Journal of Pharmacology. 91: 255-9. PMID 6311579 DOI: 10.1016/0014-2999(83)90474-0  1
1983 Meldrum BS, Croucher MJ, Badman G, Collins JF. Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, Papio papio. Neuroscience Letters. 39: 101-4. PMID 6138738 DOI: 10.1016/0304-3940(83)90172-6  1
1983 Meldrum BS, Croucher MJ, Czuczwar SJ, Collins JF, Curry K, Joseph M, Stone TW. A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid. Neuroscience. 9: 925-30. PMID 6137790 DOI: 10.1016/0306-4522(83)90281-6  1
1982 Griffiths T, Evans MC, Meldrum BS. Intracellular sites of early calcium accumulation in the rat hippocampus during status epilepticus. Neuroscience Letters. 30: 329-34. PMID 7110639 DOI: 10.1016/0304-3940(82)90421-9  1
1982 Croucher MJ, Collins JF, Meldrum BS. Anticonvulsant action of excitatory amino acid antagonists. Science (New York, N.Y.). 216: 899-901. PMID 7079744  1
1982 Chapman AG, Riley K, Evans MC, Meldrum BS. Acute effects of sodium valproate and gamma-vinyl GABA on regional amino acid metabolism in the rat brain: incorporation of 2-[14C]glucose into amino acids. Neurochemical Research. 7: 1089-105. PMID 6817155 DOI: 10.1007/BF00964888  1
1982 Meldrum BS, Anlezark GM, Adam HK, Greenwood DT. Anticonvulsant and proconvulsant properties of viloxazine hydrochloride: pharmacological and pharmacokinetic studies in rodents and the epileptic baboon. Psychopharmacology. 76: 212-7. PMID 6808538 DOI: 10.1007/BF00432547  1
1982 Horton RW, Prestwich SA, Meldrum BS. gamma-Aminobutyric acid and benzodiazepine binding sites in audiogenic seizure-susceptible mice. Journal of Neurochemistry. 39: 864-70. PMID 6284878  1
1981 Meldrum BS, Menini C, Naquet R, Riche D, Silva-Comte C. Absence of seizure activity following focal cerebral injection of enkephalins in a primate. Regulatory Peptides. 2: 383-90. PMID 7302294 DOI: 10.1016/0167-0115(81)90020-3  1
1980 Ben-Ari Y, Tremblay E, Ottersen OP, Meldrum BS. The role of epileptic activity in hippocampal and "remote" cerebral lesions induced by kainic acid. Brain Research. 191: 79-97. PMID 7378761 DOI: 10.1016/0006-8993(80)90316-9  1
1980 Horton RW, Pedley TA, Meldrum BS. Regional cerebral blood flow in the rat as determined by particle distribution and by diffusible tracer. Stroke; a Journal of Cerebral Circulation. 11: 39-44. PMID 7355428  1
1980 Horton RW, Meldrum BS, Pedley TA, McWilliam JR. Regional cerebral blood flow in the rat during prolonged seizure activity. Brain Research. 192: 399-412. PMID 6769547 DOI: 10.1016/0006-8993(80)90892-6  1
1979 Horton RW, Collins JF, Anlezark GM, Meldrum BS. Convulsant and anticonvulsant actions in DBA/2 mice of compounds blocking the reuptake of GABA. European Journal of Pharmacology. 59: 75-83. PMID 510401 DOI: 10.1016/0014-2999(79)90026-8  1
1979 Horton RW, Chapman AG, Meldrum BS. The convulsant action of hydrazides and regional changes in cerebral gamma-aminobutyric acid and pyridoxal phosphate concentrations. Journal of Neurochemistry. 33: 745-9. PMID 479889  1
1979 Meldrum BS, Menini C, Stutzmann JM, Naquet R. Effects of opiate-like peptides, morphine, and naloxone in the photosensitive baboon, Papio papio. Brain Research. 170: 333-48. PMID 223724 DOI: 10.1016/0006-8993(79)90111-2  1
1979 Ancri D, Naquet R, Basset JY, Ménini C, Lonchampt MF, Meldrum BS, Stutzmann JM. [Correlation between the regional blood volume and epileptic seizures in Papio papio]. Comptes Rendus Des SéAnces De L'AcadéMie Des Sciences. SéRie D, Sciences Naturelles. 289: 343-6. PMID 117933  1
1979 Meldrum BS, Horton RW, Bloom SR, Butler J, Keenan J. Endocrine factors and glucose metabolism during prolonged seizures in baboons. Epilepsia. 20: 527-33. PMID 113209  1
1979 Pedley TA, Horton RW, Meldrum BS. Electroencephalographic and behavioral effects of a GABA agonist (muscimol) on photosensitive epilepsy in the baboon, papio papio. Epilepsia. 20: 409-16. PMID 113208  1
1979 Meldrum BS, Horton RW. Anticonvulsant action of YG 19-256 in baboons with photosensitive epilepsy. Experientia. 35: 796-7. PMID 111964 DOI: 10.1007/BF01968255  1
1979 Meldrum BS, Horton RW. Anticonvulsant activity in photosensitive baboons, Papio papio, of two new 1,5 benzodiazepines. Psychopharmacology. 60: 277-80. PMID 108705 DOI: 10.1007/BF00426668  1
1979 Meldrum BS, Menini C, Naquet R, Laurent H, Stutzmann JM. Proconvulsant, convulsant and other actions of the D- and L-stereoisomers of allylglycine in the photosensitive baboon, Papio papio. Electroencephalography and Clinical Neurophysiology. 47: 383-95. PMID 89942 DOI: 10.1016/0013-4694(79)90154-8  1
1979 Meldrum BS, Chapman AG, Horton RW. Clobazam: anticonvulsant action in animal models of epilepsy [proceedings]. British Journal of Clinical Pharmacology. 7: 59S-60S. PMID 35206  0.4
1978 Horton RW, Chapman AG, Meldrum BS. Regional changes in cerebral GABA concentration and convulsions produced by D and by L-allylglycine. Journal of Neurochemistry. 30: 1501-4. PMID 670990  1
1978 Horton RW, Jenner P, Marsden CD, Meldrum BS, Reavill C. Behavioural effects of allylglycine (2-amino-4-pentenoic acid) and 2-keto-4-pentenoic acid following focal injection into the rat cerebellum and caudate nucleus [proceedings]. British Journal of Pharmacology. 63: 381P. PMID 667460  1
1978 Horton RW, Chapman AG, Meldrum BS. Differential effects of D- and L-allylglycine (2-aminopent-4-enoic acid) on regional cerebral gamma-aminobutyrate concentrations [proceedings]. Biochemical Society Transactions. 6: 115-8. PMID 640135  1
1978 Tarsy D, Pycock CJ, Meldrum BS, Marsden CD. Focal contralateral myoclonus produced by inhibition of GABA action in the caudate nucleus of rats. Brain : a Journal of Neurology. 101: 143-62. PMID 638722  1
1978 Anlezark GM, Horton RW, Meldrum BS. Dopamine agonists and audiogenic seizures: the relationship between protection against seizures and changes in monoamine metabolism. Biochemical Pharmacology. 27: 2821-8. PMID 581645 DOI: 10.1016/0006-2952(78)90196-X  1
1978 Anlezark GM, Horton RW, Meldrum BS. Dopamine agonists and reflex epilepsy. Advances in Biochemical Psychopharmacology. 19: 383-8. PMID 99989  1
1978 Chapman AG, Horton RW, Meldrum BS. Anticonvulsant action of a 1,5-benzodiazepine, clobazam, in reflex epilepsy. Epilepsia. 19: 293-9. PMID 98317  1
1978 Horton RW, Meldrum BS. Catalytic inhibitors of GABA-transaminase as anticonvulsants in baboons with photosensitive epilepsy [proceedings]. British Journal of Pharmacology. 63: 390P. PMID 96902  1
1977 Sawaya MC, Dolphin A, Jenner P, Marsden CD, Meldrum BS. Noradrenaline-sensitive adenylate cyclase in slices of mouse limbic forebrain: characterisation and effect of dopaminergic agonists. Biochemical Pharmacology. 26: 1877-84. PMID 911341  0.52
1977 Horton RW, Meldrum BS. A comparison of the effects of allylglycine and 2-keto-4-pentenoic acid on cerebral glutamic acid decarboxylase activity and convulsions in mice [proceedings]. British Journal of Pharmacology. 61: 477P. PMID 588827  1
1977 Meldrum BS, Anlezark GM, Marsden CD. Acute dystonia as an idiosyncratic response to neuroleptics in baboons. Brain : a Journal of Neurology. 100: 313-26. PMID 406964  0.52
1977 Horton RW, Anlezark GM, Sawaya MC, Meldrum BS. Monoamine and GABA metabolism and the anticonvulsant action of di-n-propylacetate and ethanolamine-O-sulphate. European Journal of Pharmacology. 41: 387-97. PMID 139317 DOI: 10.1016/0014-2999(77)90259-X  1
1976 Horton RW, Meldrum BS, Sawaya MC, Stephenson JD. Picrotoxin convulsions and GABA metabolism after injection of anticonvulsants in chicks. European Journal of Pharmacology. 40: 101-6. PMID 991920 DOI: 10.1016/0014-2999(76)90359-9  1
1976 Horton RW, Meldrum BS. Preconvulsive changes in brain glucose metabolism following drugs inhibiting glutamate decarboxylase. Journal of Neurochemistry. 26: 805-9. PMID 965969  1
1976 Meldrum BS, Smyth MR, Franklin-Smyth W, Clifford JM. The relationship between the anticonvulsant properties of SC-13504 and its plasma levels, measured by polarography, in baboons with photosensitive epilepsy. Psychopharmacology. 51: 59-64. PMID 827776 DOI: 10.1007/BF00426322  1
1976 Anlezark GM, Marsden CD, Meldrum BS. Proceedings: A primate model of acute dystonic reaction to neuroleptics. British Journal of Pharmacology. 56: 381P. PMID 816407  0.52
1976 Anlezark GM, Horton RW, Meldrum BS, Sawaya MC, Stephenson JD. Proceedings: gamma-Aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate. British Journal of Pharmacology. 56: 383P-384P. PMID 769882  1
1975 Sawaya MC, Horton RW, Meldrum BS. Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA. Epilepsia. 16: 649-55. PMID 9890792  1
1975 Meldrum BS, Anlezark G, Balzamo E, Horton RW, Trimble M. Photically induced epilepsy in Papio papio as a model for drug studies. Advances in Neurology. 10: 119-32. PMID 1170711  1
1975 Marsden CD, Meldrum BS, Pycock C, Tarsy D. Focal myoclonus produced by injection of picrotoxin into the caudate nucleus of the rat. The Journal of Physiology. 246: 96P. PMID 1142296  1
1975 Meldrum BS, Stephenson JD. Enhancement of picrotoxin convulsions in chicks and mice by the prior intraperitoneal injection of hypertonic GABA or mannitol. European Journal of Pharmacology. 30: 368-71. PMID 1126369 DOI: 10.1016/0014-2999(75)90124-7  1
1975 Meldrum BS, BChir, Horton RW, Toseland PA. A primate model for testing anticonvulsant drugs. Archives of Neurology. 32: 289-94. PMID 237498 DOI: 10.1001/archneur.1975.00490470033003  1
1975 Meldrum BS, Horton RW, Sawaya MC. The convulsant action of methyldithiocarbazinate: a comparison with other sulphur-containing hydrazides. Journal of Neurochemistry. 24: 1003-9. PMID 167122  1
1974 Meldrum BS, Fariello RG, Puil EA, Derouaux M, Naquet R. Delta9-tetrahydrocannabinol and epilepsy in the photosensitive baboon, Papio papio. Epilepsia. 15: 255-64. PMID 4525183  1
1974 Meldrum BS, Horton RW, Brierley JB. Epileptic brain damage in adolescent baboons following seizures induced by allylgycine. Brain : a Journal of Neurology. 97: 407-18. PMID 4434186 DOI: 10.1093/brain/97.1.407  1
1973 Meldrum BS, Horton RW. Physiology of status epilepticus in primates. Archives of Neurology. 28: 1-9. PMID 4629380  1
1973 Horton RW, Meldrum BS, Bachelard HS. Enzymic and cerebral metabolic effects of 2-deoxy-D-glucose. Journal of Neurochemistry. 21: 507-20. PMID 4270246  1
1973 Horton RW, Meldrum BS. Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. British Journal of Pharmacology. 49: 52-63. PMID 4207045  1
1973 Meldrum BS, Horton RW. Cerebral functional effects of 2-deoxy-D-glucose and 3-O-methylglucose in rhesus monkeys. Electroencephalography and Clinical Neurophysiology. 35: 59-66. PMID 4123265 DOI: 10.1016/0013-4694(73)90131-4  1
1972 Brierley JB, Horton RW, Meldrum BS. Physiological observations during prolonged epileptic seizures in primates and their relation to subsequent brain damage. The Journal of Physiology. 222: 69P-70P. PMID 5037105  1
1972 Meldrum BS, Balzamo E, Wada JA, Vuillon-Cacciuttolo G. Effects of L-tryptophan, L-3, 4, dihydroxyphenylalanine and tranylcypromine on the electroencephalogram and on photically induced epilepsy in the baboon, Papio papio. Physiology & Behavior. 9: 615-21. PMID 4209277 DOI: 10.1016/0031-9384(72)90020-0  1
1972 Wada JA, Balzamo E, Meldrum BS, Naquet R. Behavioural and electrographic effects of L-5-hydroxytryptophan and D, L-parachlorophenyl-alanine on epileptic Senegalese baboon (Papio papio). Electroencephalography and Clinical Neurophysiology. 33: 520-6. PMID 4116436 DOI: 10.1016/0013-4694(72)90216-7  1
1971 Bhargava VK, Meldrum BS. Blockade by eserine of the cerebral cortical effects of strychnine and curare. Nature: New Biology. 230: 152. PMID 5279471  1
1971 Bhargava VK, Meldrum BS. Cholinergic cortical evoked potentials. The Indian Journal of Medical Research. 59: 931-9. PMID 5121771  1
1971 Balzano E, Meldrum BS, Naquet R, Vuillon-Cacciuttolo G. [Modifications of the EEG and the photosensitivity of Papio papio under the effect of different derivatives of ergot]. Revue D'éLectroencéPhalographie Et De Neurophysiologie Clinique. 1: 219-30. PMID 5006269 DOI: 10.1016/S0370-4475(71)80064-3  1
1971 Meldrum BS, Horton RW. Convulsive effects of 4-deoxypyridoxine and of bicuculline in photosensitive baboons (Papio papio) and in rhesus monkeys (Macaca mulatta). Brain Research. 35: 419-36. PMID 5002707 DOI: 10.1016/0006-8993(71)90485-9  1
1971 Meldrum BS, Naquet R. Effects of psilocybin, dimethyltryptamine, mescaline and various lysergic acid derivatives on the EEG and on photically induced epilepsy in the baboon (Papio papio). Electroencephalography and Clinical Neurophysiology. 31: 563-72. PMID 4111479 DOI: 10.1016/0013-4694(71)90072-1  1
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