Year |
Citation |
Score |
2022 |
Gallegos EM, Reed TD, Mathes FA, Guevara NV, Neau DB, Huang W, Newcomer ME, Gilbert NC. Helical remodeling augments 5-lipoxygenase activity in the synthesis of pro-inflammatory mediators. The Journal of Biological Chemistry. 102282. PMID 35863431 DOI: 10.1016/j.jbc.2022.102282 |
0.337 |
|
2020 |
Gilbert NC, Gerstmeier J, Schexnaydre EE, Börner F, Garscha U, Neau DB, Werz O, Newcomer ME. Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nature Chemical Biology. PMID 32393899 DOI: 10.1038/S41589-020-0544-7 |
0.452 |
|
2019 |
Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, et al. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Science Immunology. 4. PMID 30952805 DOI: 10.1126/sciimmunol.aav7517 |
0.301 |
|
2019 |
Pakhomova S, Boeglin WE, Neau DB, Bartlett SG, Brash AR, Newcomer ME. An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Science : a Publication of the Protein Society. PMID 30861228 DOI: 10.2210/Pdb6Ns2/Pdb |
0.386 |
|
2018 |
Gilbert NC, Neau DB, Newcomer ME. Expression of an 8R-Lipoxygenase From the Coral Plexaura homomalla. Methods in Enzymology. 605: 33-49. PMID 29909831 DOI: 10.1016/Bs.Mie.2018.02.010 |
0.336 |
|
2017 |
Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255035 DOI: 10.2210/Pdb6Blx/Pdb |
0.307 |
|
2017 |
Su M, Li Y, Wyborny S, Neau D, Chakravarthy S, Levine B, Colbert CL, Sinha SC. BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy. Protein Science : a Publication of the Protein Society. PMID 28218432 DOI: 10.1002/Pro.3140 |
0.657 |
|
2016 |
Crochet RB, Kim JD, Lee H, Yim YS, Kim SG, Neau D, Lee YH. Crystal Structure of Heart 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB2) and the Inhibitory Influence of Citrate on Substrate Binding. Proteins. PMID 27802586 DOI: 10.1002/Prot.25204 |
0.45 |
|
2016 |
Silvers MA, Pakhomova S, Neau DB, Silvers WC, Anzalone N, Taylor CM, Waldrop GL. The Crystal Structure of Carboxyltransferase from Staphylococcus aureus Bound to the Antibacterial Agent Moiramide B. Biochemistry. PMID 27471863 DOI: 10.1021/Acs.Biochem.6B00641 |
0.349 |
|
2016 |
Dhindwal S, Gomez-Gil L, Neau DB, Pham TT, Sylvestre M, Eltis LD, Bolin JT, Kumar P. The structural basis of the enhanced pollutant-degrading capabilities of an engineered biphenyl dioxygenase. Journal of Bacteriology. PMID 26953337 DOI: 10.1128/Jb.00952-15 |
0.654 |
|
2015 |
Jensen JL, Balbo A, Neau DB, Chakravarthy S, Zhao H, Sinha SC, Colbert CL. Mechanistic implications of the unique structural features and dimerization of the cytoplasmic domain of the Pseudomonas sigma regulator, PupR. Biochemistry. PMID 26313375 DOI: 10.1021/Acs.Biochem.5B00826 |
0.647 |
|
2015 |
Broussard TC, Pakhomova S, Neau DB, Bonnot R, Waldrop GL. Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry. 54: 3860-70. PMID 26020841 DOI: 10.1021/Acs.Biochem.5B00340 |
0.367 |
|
2015 |
Jensen JL, Indurthi VS, Neau DB, Vetter SW, Colbert CL. Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex. Acta Crystallographica. Section D, Biological Crystallography. 71: 1176-83. PMID 25945582 DOI: 10.1107/S1399004715004216 |
0.663 |
|
2014 |
Cavalier MC, Pierce AD, Wilder PT, Alasady MJ, Hartman KG, Neau DB, Foley TL, Jadhav A, Maloney DJ, Simeonov A, Toth EA, Weber DJ. Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53: 6628-40. PMID 25268459 DOI: 10.1021/Bi5005552 |
0.385 |
|
2014 |
Neau DB, Bender G, Boeglin WE, Bartlett SG, Brash AR, Newcomer ME. Crystal structure of a lipoxygenase in complex with substrate: the arachidonic acid-binding site of 8R-lipoxygenase. The Journal of Biological Chemistry. 289: 31905-13. PMID 25231982 DOI: 10.1074/Jbc.M114.599662 |
0.454 |
|
2014 |
Kobe MJ, Neau DB, Mitchell CE, Bartlett SG, Newcomer ME. The structure of human 15-lipoxygenase-2 with a substrate mimic. The Journal of Biological Chemistry. 289: 8562-9. PMID 24497644 DOI: 10.1074/Jbc.M113.543777 |
0.46 |
|
2013 |
Broussard TC, Kobe MJ, Pakhomova S, Neau DB, Price AE, Champion TS, Waldrop GL. The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase Structure. 21: 650-657. PMID 23499019 DOI: 10.1016/J.Str.2013.02.001 |
0.435 |
|
2012 |
Cavalier MC, Yim YS, Asamizu S, Neau D, Almabruk KH, Mahmud T, Lee YH. Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex Plos One. 7. PMID 23028689 DOI: 10.1371/Journal.Pone.0044934 |
0.419 |
|
2012 |
Gilbert NC, Rui Z, Neau DB, Waight MT, Bartlett SG, Boeglin WE, Brash AR, Newcomer ME. Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3222-9. PMID 22516296 DOI: 10.1096/Fj.12-205286 |
0.412 |
|
2012 |
Cavalier MC, Kim SG, Neau D, Lee YH. Molecular basis of the fructose-2,6-bisphosphatase reaction of PFKFB3: Transition state and the C-terminal function Proteins: Structure, Function and Bioinformatics. 80: 1143-1153. PMID 22275052 DOI: 10.1002/Prot.24015 |
0.354 |
|
2011 |
French JB, Neau DB, Ealick SE. Characterization of the structure and function of Klebsiella pneumoniae allantoin racemase. Journal of Molecular Biology. 410: 447-60. PMID 21616082 DOI: 10.1016/J.Jmb.2011.05.016 |
0.45 |
|
2011 |
Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, Newcomer ME. The structure of human 5-lipoxygenase. Science (New York, N.Y.). 331: 217-9. PMID 21233389 DOI: 10.1126/Science.1197203 |
0.434 |
|
2009 |
Neau DB, Gilbert NC, Bartlett SG, Boeglin W, Brash AR, Newcomer ME. The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity. Biochemistry. 48: 7906-15. PMID 19594169 DOI: 10.1021/Bi900084M |
0.416 |
|
2007 |
Neau DB, Gilbert NC, Bartlett SG, Dassey A, Newcomer ME. Improving protein crystal quality by selective removal of a Ca 2+-dependent membrane-insertion loop Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63: 972-975. PMID 18007054 DOI: 10.1107/S1744309107050993 |
0.361 |
|
2007 |
Vander Kooi CW, Jusino MA, Perman B, Neau DB, Bellamy HD, Leahy DJ. Structural basis for ligand and heparin binding to neuropilin B domains. Proceedings of the National Academy of Sciences of the United States of America. 104: 6152-7. PMID 17405859 DOI: 10.1073/Pnas.0700043104 |
0.395 |
|
2005 |
Fortin PD, MacPherson I, Neau DB, Bolin JT, Eltis LD. Directed evolution of a ring-cleaving dioxygenase for polychlorinated biphenyl degradation. The Journal of Biological Chemistry. 280: 42307-14. PMID 16227200 DOI: 10.1074/Jbc.M510456200 |
0.674 |
|
2002 |
Dai S, Vaillancourt FH, Maaroufi H, Drouin NM, Neau DB, Snieckus V, Bolin JT, Eltis LD. Identification and analysis of a bottleneck in PCB biodegradation. Nature Structural Biology. 9: 934-9. PMID 12415290 DOI: 10.1038/Nsb866 |
0.633 |
|
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