Jaime M. Hatcher - Related publications

Affiliations: 
Emory University School of Medicine, Atlanta, GA, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Liu M, Qian T, Zhou W, Tao X, Sang S, Zhao L. Beneficial effects of low-dose lithium on cognitive ability and pathological alteration of Alzheimer's disease transgenic mice model. Neuroreport. PMID 32639272 DOI: 10.1097/WNR.0000000000001499   
2020 Liu DQ, Lu S, Zhang L, Huang YR, Ji M, Sun XY, Liu XG, Liu RT. Yeast-Based Aβ1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice. Vaccines. 8. PMID 32630299 DOI: 10.3390/vaccines8030351   
2020 Ferreira S, Pitman KA, Wang S, Summers BS, Bye N, Young KM, Cullen CL. Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain. Journal of Neuroscience Research. PMID 32557778 DOI: 10.1002/jnr.24672   
2020 Liu J, Yu C, Li R, Liu K, Jin G, Ge R, Tang F, Cui S. High-altitude Tibetan fermented milk ameliorated cognitive dysfunction by modified gut microbiota in Alzheimer's disease transgenic mice. Food & Function. PMID 32458851 DOI: 10.1039/c9fo03007g   
2020 Lin SY, Wang TQ, Xu LT, Lai XX, Shen Y, Lin JW, Gao SY, Hu HY. Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 3019674. PMID 32419798 DOI: 10.1155/2020/3019674   
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818   
2020 Chen Y, Fang L, Chen S, Zhou H, Fan Y, Lin L, Li J, Xu J, Chen Y, Ma Y, Chen Y. Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease. Biomed Research International. 2020: 8456596. PMID 32596386 DOI: 10.1155/2020/8456596   
2020 Bracko O, Vinarcsik LK, Cruz Hernández JC, Ruiz-Uribe NE, Haft-Javaherian M, Falkenhain K, Ramanauskaite EM, Ali M, Mohapatra A, Swallow MA, Njiru BN, Muse V, Michelucci PE, Nishimura N, Schaffer CB. High fat diet worsens Alzheimer's disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow. Scientific Reports. 10: 9884. PMID 32555372 DOI: 10.1038/s41598-020-65908-y   
2020 Wei JP, Wen W, Dai Y, Qin LX, Wen YQ, Duan DD, Xu SJ. Drinking water temperature affects cognitive function and progression of Alzheimer's disease in a mouse model. Acta Pharmacologica Sinica. PMID 32451415 DOI: 10.1038/s41401-020-0407-5   
2020 Tanaka M, Kiyohara H, Yoshino A, Nakano A, Takata F, Dohgu S, Kataoka Y, Matsui T. Brain-transportable soy dipeptide, Tyr-Pro, attenuates amyloid β peptide-induced memory impairment in mice. Npj Science of Food. 4: 7. PMID 32377566 DOI: 10.1038/s41538-020-0067-3   
2020 Kim DH, Kim HA, Han YS, Jeon WK, Han JS. Recognition memory impairments and amyloid-beta deposition of the retrosplenial cortex at the early stage of 5XFAD mice. Physiology & Behavior. 112891. PMID 32442584 DOI: 10.1016/j.physbeh.2020.112891   
2020 Sun C, Qiu X, Wang Y, Liu J, Li Q, Jiang H, Li S, Song C. Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice. Neuroscience Letters. 135192. PMID 32619650 DOI: 10.1016/j.neulet.2020.135192   
2020 Wu Q, Wang B, Li QF, Zhang X, Ntim M, Wu XF, Li N, Zhu DD, Jiang R, Yang JY, Yuan YH, Li S. SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice. Frontiers in Aging Neuroscience. 12: 145. PMID 32625077 DOI: 10.3389/fnagi.2020.00145   
2020 Luo Y, Yang W, Li N, Yang X, Zhu B, Wang C, Hou W, Wang X, Wen H, Tian X. Anodal Transcranial Direct Current Stimulation Can Improve Spatial Learning and Memory and Attenuate Aβ Burden at the Early Stage of Alzheimer's Disease in APP/PS1 Transgenic Mice. Frontiers in Aging Neuroscience. 12: 134. PMID 32595486 DOI: 10.3389/fnagi.2020.00134   
2020 Mei X, Zhu L, Zhou Q, Li X, Chen Z. Interplay of curcumin and its liver metabolism on the level of Aβ in the brain of APP/PS1 mice before AD onset. Pharmacological Reports : Pr. PMID 32468514 DOI: 10.1007/s43440-020-00116-z   
2020 Sun Y, Sommerville NR, Liu JYH, Ngan MP, Poon D, Ponomarev ED, Lu Z, Kung JSC, Rudd JA. Intra-gastrointestinal amyloid-β1-42 oligomers perturb enteric function and induce Alzheimer's disease pathology. The Journal of Physiology. PMID 32617993 DOI: 10.1113/JP279919   
2020 Zaldua S, Damen FC, Pisharody R, Thomas R, Fan KD, Ekkurthi GK, Scheinman SB, Alahmadi S, Marottoli FM, Alford S, Cai K, Tai LM. Epidermal growth factor treatment of female mice that express at an age of advanced pathology mitigates behavioral and cerebrovascular dysfunction. Heliyon. 6: e03919. PMID 32478184 DOI: 10.1016/j.heliyon.2020.e03919   
2020 Zameer S, Alam M, Hussain S, Vohora D, Ali J, Akhtar M. Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet. Brain Research Bulletin. PMID 32389800 DOI: 10.1016/j.brainresbull.2020.04.010   
2020 Li KY, Gong PF, Li JT, Xu NJ, Qin S. Morphological and molecular alterations of reactive astrocytes without proliferation in cerebral cortex of an APP/PS1 transgenic mouse model and Alzheimer's patients. Glia. PMID 32469469 DOI: 10.1002/glia.23845   
2020 Wan L, Zhang Q, Luo H, Xu Z, Huang S, Yang F, Liu Y, Mahaman YAR, Ke D, Wang Q, Liu R, Wang JZ, Shu X, Wang X. polysaccharide attenuates Aβ toxicity and cognitive defects in APP/PS1 mice. Aging. 12. PMID 32652518 DOI: 10.18632/aging.103445   
2020 Huang J, van Zijl PCM, Han X, Dong CM, Cheng GWY, Tse KH, Knutsson L, Chen L, Lai JHC, Wu EX, Xu J, Chan KWY. Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI. Science Advances. 6: eaba3884. PMID 32426510 DOI: 10.1126/sciadv.aba3884   
2020 Wahle T, Sofranko A, Dekkers S, Miller MR, Heusinkveld HJ, Albrecht C, Cassee FR, Schins RPF. Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascular disease. Neurochemistry International. 104755. PMID 32422323 DOI: 10.1016/j.neuint.2020.104755   
2020 Falangola MF, Nie X, Ward R, McKinnon ET, Dhiman S, Nietert PJ, Helpern JA, Jensen JH. Diffusion MRI detects early brain microstructure abnormalities in 2-month-old 3×Tg-AD mice. Nmr in Biomedicine. e4346. PMID 32557874 DOI: 10.1002/nbm.4346   
2020 Zhao Y, Qian R, Zhang J, Liu F, Iqbal K, Dai CL, Gong CX. Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice. Alzheimer's Research & Therapy. 12: 70. PMID 32513253 DOI: 10.1186/s13195-020-00639-w   
2020 Park SY, Kang JY, Lee T, Nam D, Jeon CJ, Kim JB. Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse Model. Cells. 9. PMID 32455709 DOI: 10.3390/cells9051275   
2020 Tyagi A, Mirita C, Taher N, Shah I, Moeller E, Tyagi A, Chong T, Pugazhenthi S. Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165849. PMID 32485218 DOI: 10.1016/j.bbadis.2020.165849   
2020 Christensen A, Pike CJ. Staining and Quantification of β-Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 2144: 211-221. PMID 32410038 DOI: 10.1007/978-1-0716-0592-9_19   
2020 Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Kawai K, Murakami M, Tanaka T, Goda W, Goto M, Yamamoto T, Hashimoto T, Yamada K, Shibata T, Misawa H, et al. Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model. Acta Neuropathologica Communications. 8: 67. PMID 32398151 DOI: 10.1186/s40478-020-00936-3   
2020 Wu J, Zhu X, Lin H, Chen Z, Tang H, Wang Y. Gender differences in the bile acid profiles of APP/PS1 transgenic AD mice. Brain Research Bulletin. PMID 32437836 DOI: 10.1016/j.brainresbull.2020.05.003   
2020 Izumi H, Kawahata I, Shinoda Y, Helmstetter FJ, Fukunaga K. SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in App Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling. International Journal of Molecular Sciences. 21. PMID 32481611 DOI: 10.3390/ijms21113833   
2020 Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y. Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32475008 DOI: 10.1096/fj.201902731RR   
2020 Watt G, Chesworth R, Przybyla M, Ittner A, Garner B, Ittner LM, Karl T. Chronic cannabidiol (CBD) treatment did not exhibit beneficial effects in 4-month-old male TAU58/2 transgenic mice. Pharmacology, Biochemistry, and Behavior. 172970. PMID 32562718 DOI: 10.1016/j.pbb.2020.172970   
2020 Shi Y, Zhang L, Gao X, Zhang J, Ben Abou M, Liang G, Meng Q, Hepner A, Eckenhoff MF, Wei H. Intranasal Dantrolene as a Disease-Modifying Drug in Alzheimer 5XFAD Mice. Journal of Alzheimer's Disease : Jad. PMID 32623395 DOI: 10.3233/JAD-200227   
2020 He Z, Yang Y, Xing Z, Zuo Z, Wang R, Gu H, Qi F, Yao Z. Intraperitoneal injection of IFN-γ restores microglial autophagy, promotes amyloid-β clearance and improves cognition in APP/PS1 mice. Cell Death & Disease. 11: 440. PMID 32514180 DOI: 10.1038/s41419-020-2644-4   
2020 Do J, Kim N, Jeon SH, Gee MS, Ju YJ, Kim JH, Oh MS, Lee JK. Trans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice. International Journal of Molecular Sciences. 21. PMID 32599846 DOI: 10.3390/ijms21124492   
2020 Liu Y, Wang J, Hsiung GR, Song W. Trehalose Inhibits Aβ Generation and Plaque Formation in Alzheimer's Disease. Molecular Neurobiology. PMID 32488697 DOI: 10.1007/s12035-020-01942-1   
2020 Zhang Y, Fung ITH, Sankar P, Chen X, Robison LS, Ye L, D'Souza SS, Salinero AE, Kuentzel ML, Chittur SV, Zhang W, Zuloaga KL, Yang Q. Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model. Journal of Immunology (Baltimore, Md. : 1950). PMID 32503894 DOI: 10.4049/jimmunol.2000037   
2020 Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, Ferreira IL, Fontes AR, Mastrella G, Pinheiro P, Valero J, Rego AC. Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model. Neurobiology of Aging. 92: 98-113. PMID 32417750 DOI: 10.1016/j.neurobiolaging.2020.04.003   
2020 Jia L, Wang W, Yan Y, Hu R, Sang J, Zhao W, Wang Y, Wei W, Cui W, Yang G, Lu F, Zheng J, Liu F. General Aggregation-Induced Emission Probes for Amyloid Inhibitors with Dual Inhibition Capacity against Amyloid β-Protein and α-Synuclein. Acs Applied Materials & Interfaces. PMID 32584021 DOI: 10.1021/acsami.0c07745   
2020 Beyer MMS, Lonnemann N, Remus A, Latz E, Heneka MT, Korte M. Enduring changes in neuronal function upon systemic inflammation are NLRP3 inflammasome dependent. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32499379 DOI: 10.1523/JNEUROSCI.0200-20.2020   
2020 Cui W, Sun C, Ma Y, Wang S, Wang X, Zhang Y. Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model. Molecular Medicine Reports. PMID 32468017 DOI: 10.3892/mmr.2020.11154   
2020 Delabar JM, Ortner M, Simon S, Wijkhuisen A, Feraudet-Tarisse C, Pegon J, Vidal E, Hirschberg Y, Dubois B, Potier MC. Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. Alzheimer's & Dementia (New York, N. Y.). 6: e12046. PMID 32642550 DOI: 10.1002/trc2.12046   
2020 Maron R, Armony G, Tsoory M, Wilchek M, Frenkel D, Arnon R. Peptide Interference with APP and Tau Association: Relevance to Alzheimer's Disease Amelioration. International Journal of Molecular Sciences. 21. PMID 32380752 DOI: 10.3390/ijms21093270   
2020 Farkhondeh T, Khan H, Aschner M, Samini F, Pourbagher-Shahri AM, Aramjoo H, Roshanravan B, Hoyte C, Mehrpour O, Samarghandian S. Impact of Cannabis-Based Medicine on Alzheimer's disease by Focusing on the Amyloid β- Modifications: A Systematic Study. Cns & Neurological Disorders Drug Targets. PMID 32640965 DOI: 10.2174/1871527319666200708130745   
2020 Gotoh N, Saito Y, Hata S, Saito H, Ojima D, Murayama C, Shigeta M, Abe T, Konno D, Matsuzaki F, Suzuki T, Yamamoto T. Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of Alcadein α-deficient mice. The Journal of Biological Chemistry. PMID 32467230 DOI: 10.1074/jbc.RA119.012386   
2020 Kim S, Nam Y, Kim C, Lee H, Hong S, Kim HS, Shin SJ, Park YH, Mai HN, Oh SM, Kim KS, Yoo DH, Chung WK, Chung H, Moon M. Neuroprotective and Anti-Inflammatory Effects of Low-Moderate Dose Ionizing Radiation in Models of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32456197 DOI: 10.3390/ijms21103678   
2020 Pang S, Sun C, Gao S, Yang Y, Pan X, Zhang L. Evodiamine derivatives improve cognitive abilities in APP/PS1 transgenic mouse models of Alzheimer's disease. Animal Models and Experimental Medicine. 3: 193-199. PMID 32613178 DOI: 10.1002/ame2.12126   
2020 Rosas-Hernandez H, Cuevas E, Raymick JB, Robinson BL, Sarkar S. Impaired amyloid beta clearance and brain microvascular dysfunction are present in the Tg-SwDI mouse model of Alzheimer's disease. Neuroscience. PMID 32450297 DOI: 10.1016/j.neuroscience.2020.05.024   
2020 Gao L, Li X, Meng S, Ma T, Wan L, Xu S. Chlorogenic Acid Alleviates Aβ-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway. Drug Design, Development and Therapy. 14: 1705-1716. PMID 32440096 DOI: 10.2147/DDDT.S235969   
2020 Ghosh A, Mizuno K, Tiwari SS, Proitsi P, Gomez Perez-Nievas B, Glennon E, Martinez-Nunez RT, Giese KP. Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing. Translational Psychiatry. 10: 192. PMID 32546772 DOI: 10.1038/s41398-020-00882-7