David Wagner - Related publications

Affiliations: 
Marquette University, Milwaukee, WI, United States 
Area:
GABA(A) receptor structure-function; GABA(A) receptor kinetics
Website:
http://biology.marquette.edu/faculty/wagner.html
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Lu X, Zorumski CF, Mennerick S. Lack of Neurosteroid Selectivity at δ vs. γ2-Containing GABA Receptors in Dentate Granule Neurons. Frontiers in Molecular Neuroscience. 13: 6. PMID 32038169 DOI: 10.3389/fnmol.2020.00006   
2020 Amrutkar DV, Dyhring T, Jacobsen TA, Larsen JS, Sandager-Nielsen K. Anti-Tremor Action of Subtype Selective Positive Allosteric Modulators of GABA Receptors in a Rat Model of Essential Tremors. Cerebellum (London, England). PMID 31989440 DOI: 10.1007/s12311-020-01106-w   
2020 Zhang X, Lang Y, Sun L, Zhang W, Lin W, Cui L. Clinical characteristics and prognostic analysis of anti-gamma-aminobutyric acid-B (GABA-B) receptor encephalitis in Northeast China. Bmc Neurology. 20: 1. PMID 31900128 DOI: 10.1186/s12883-019-1585-y   
2020 Sharma J, Bhardwaj V, Das P, Purohit R. Identification of naturally originated molecules as γ-aminobutyric acid receptor antagonist. Journal of Biomolecular Structure & Dynamics. 1-17. PMID 31980008 DOI: 10.1080/07391102.2020.1720818   
2020 Chabriat H, Bassetti CL, Marx U, Picarel-Blanchot F, Sors A, Gruget C, Saba B, Wattez M, Audoli ML, Hermann DM. Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study. Trials. 21: 136. PMID 32014032 DOI: 10.1186/s13063-020-4072-2   
2020 Qudah T, Quek GX, Indurthi D, Karim N, Halliday JI, Absalom N, McLeod MD, Chebib M. AE succinimide, an analogue of methyllycaconitine, when bound generates a non-conducting conformation of the α4β2 nicotinic acetylcholine receptor. Acs Chemical Neuroscience. PMID 31898891 DOI: 10.1021/acschemneuro.9b00525   
2020 Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, et al. Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science (New York, N.Y.). 367: 643-652. PMID 32029621 DOI: 10.1126/science.aaw3242   
2020 Su Z, Wu Y. A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily. Computational and Structural Biotechnology Journal. 18: 258-270. PMID 32021664 DOI: 10.1016/j.csbj.2019.12.016   
2020 Yamato K, Nakata Y, Takashima M, Ozoe F, Asahi M, Kobayashi M, Ozoe Y. Effects of intersubunit amino acid substitutions on GABA receptor sensitivity to the ectoparasiticide fluralaner. Pesticide Biochemistry and Physiology. 163: 123-129. PMID 31973848 DOI: 10.1016/j.pestbp.2019.11.001   
2020 Xu X, Godoy-Ruiz R, Adipietro KA, Peralta C, Ben-Hail D, Varney KM, Cook ME, Roth BM, Wilder PT, Cleveland T, Grishaev A, Neu HM, Michel SLJ, Yu W, Beckett D, et al. Structure of the cell-binding component of the binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 31896582 DOI: 10.1073/pnas.1919490117   
2020 Umitsu M, Sakai K, Tamura-Kawakami K, Matsumoto K, Takagi J. The constitutive high affinity Met binding site in the kringle domain is dispensable for the signaling activity of hepatocyte growth factor. Journal of Biochemistry. PMID 31943091 DOI: 10.1093/jb/mvaa006   
2020 Burada AP, Vinnakota R, Kumar J. Cryo-EM structures of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture. Nature Structural & Molecular Biology. 27: 84-91. PMID 31925409 DOI: 10.1038/s41594-019-0359-y   
2020 Wang JX, Irvine MW, Burnell ES, Sapkota K, Thatcher RJ, Li M, Simorowski N, Volianskis A, Collingridge GL, Monaghan DT, Jane DE, Furukawa H. Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nature Communications. 11: 423. PMID 31969570 DOI: 10.1038/s41467-020-14321-0   
2020 Frei JN, Broadhurst RW, Bostock MJ, Solt A, Jones AJY, Gabriel F, Tandale A, Shrestha B, Nietlispach D. Conformational plasticity of ligand-bound and ternary GPCR complexes studied by F NMR of the β-adrenergic receptor. Nature Communications. 11: 669. PMID 32015348 DOI: 10.1038/s41467-020-14526-3   
2020 Kurz M, Krett AL, Bunemann M. Voltage dependence of prostanoid receptors. Molecular Pharmacology. PMID 32005759 DOI: 10.1124/mol.119.118372   
2020 Jiang X, Dulubova I, Reisman SA, Hotema M, Lee CI, Liu L, McCauley L, Trevino I, Ferguson DA, Eken Y, Wilson AK, Wigley WC, Visnick M. A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt. Bioorganic & Medicinal Chemistry Letters. 126967. PMID 32005415 DOI: 10.1016/j.bmcl.2020.126967   
2020 Mayer ML. Glutamate receptors from diverse animal species exhibit unexpected structural and functional diversity. The Journal of Physiology. PMID 31981421 DOI: 10.1113/JP279026   
2020 Jeyasingh V, Murugesan K, Lakshminarayanan S, Selvapalam N, Das G, Enoch IVMV, Piramuthu L. Most Efficient Tris(3-Aminopropyl) Amine Based Electron Deficient Tripodal Receptor for Azide. Journal of Fluorescence. PMID 31997142 DOI: 10.1007/s10895-020-02490-6   
2020 Sanchez-Soto M, Verma RK, Willette BKA, Gonye EC, Moore AM, Moritz AE, Boateng CA, Yano H, Free RB, Shi L, Sibley DR. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Science Signaling. 13. PMID 32019899 DOI: 10.1126/scisignal.aaw5885   
2020 Luo L, Sun T, Yang L, Liu A, Liu QQ, Tian QQ, Wang Y, Zhao MG, Yang Q. Scopoletin ameliorates anxiety-like behaviors in complete Freund's adjuvant-induced mouse model. Molecular Brain. 13: 15. PMID 32019580 DOI: 10.1186/s13041-020-0560-2   
2020 Pinheiro Sartori D, de Oliveira NF, Valentim JT, da Silva DMA, Serra Vasconcelos A, Maia Oliveira IC, de Castro Chaves R, Cavalcanti Capibaribe VC, de Carvalho AMR, de Oliveira Rebouças M, Macêdo D, Maia Chaves Filho AJ, de França Fonteles MM, Chavez Gutierrez SJ, Barbosa-Filho JM, et al. Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide Riparin IV: elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches. Behavioural Brain Research. 112487. PMID 31987932 DOI: 10.1016/j.bbr.2020.112487   
2020 Westphal MV, Sarott RC, Zirwes EA, Osterwald A, Guba W, Ullmer C, Grether U, Carreira EM. Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes. Chemistry (Weinheim An Der Bergstrasse, Germany). 26: 1380-1387. PMID 31961047 DOI: 10.1002/chem.201904584   
2020 Li J, Liu H, Zuo R, Yang J, Li N. Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin αβ. Chemosphere. 249: 126034. PMID 32062553 DOI: 10.1016/j.chemosphere.2020.126034   
2020 Curry SH, Marler M. Effects of ecgonine methyl ester on cognition in scopolamine-impaired and aged rats. Psychopharmacology. PMID 32034448 DOI: 10.1007/s00213-020-05460-9   
2020 Zachmann J, Kritsi E, Tapeinou A, Zoumpoulakis P, Tselios T, Matsoukas MT. A Combined Computational and Structural Approach into Understanding the Role of Peptide Binding and Activation of the Melanocortin Receptor 4. Journal of Chemical Information and Modeling. PMID 31944109 DOI: 10.1021/acs.jcim.9b01196   
2020 Nair S, Trummell HQ, Rajbhandari R, Thudi NK, Nozell SE, Warram JM, Willey CD, Yang ES, Placzek WJ, Bonner JA, Bredel M. Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer. Plos One. 15: e0229077. PMID 32069320 DOI: 10.1371/journal.pone.0229077   
2020 Landau AM, Noer O, Alstrup AKO, Audrain H, Wegener G, Gjedde A, Doudet DJ, Winterdahl M. Type of Anaesthetic Influences [C]MDL100,907 Binding to 5HT Receptors in Porcine Brain. Molecular Imaging and Biology. PMID 31993926 DOI: 10.1007/s11307-020-01476-x   
2020 Fischer A, Smieško M. Allosteric Binding Sites On Nuclear Receptors: Focus On Drug Efficacy and Selectivity. International Journal of Molecular Sciences. 21. PMID 31947677 DOI: 10.3390/ijms21020534   
2020 Yi F, Rouzbeh N, Hansen KB, Xu Y, Fanger CM, Gordon E, Paschetto K, Menniti FS, Volkmann RA. PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits. Neuropharmacology. 107971. PMID 31987864 DOI: 10.1016/j.neuropharm.2020.107971   
2020 Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB, Bhyrapuneni G, Abraham R, Jasti V. Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane hydrochloride (SUVN-911): A Novel, Potent, Selective and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression. Journal of Medicinal Chemistry. PMID 32026697 DOI: 10.1021/acs.jmedchem.9b00790   
2020 Lee HW, Sharma P, Janssen BJ, Drummond RSM, Luo Z, Hamiaux C, Collier T, Allison JR, Newcomb RD, Snowden KC. Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners. The Journal of Biological Chemistry. PMID 32071083 DOI: 10.1074/jbc.RA119.011509   
2020 Crespo M, León-Navarro DA, Ruíz MÁ, Martín M. Hyperthermia-induced seizures produce long-term effects on the functionality of adenosine A receptor in rat cerebral cortex. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 31909494 DOI: 10.1002/jdn.10000   
2020 Tang S, Sun L, Wang F. Identification of Highly Active Natural Thyroid Hormone Receptor Agonists by Pharmacophore-Based Virtual Screening. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 31997713 DOI: 10.1080/07391102.2020.1719890   
2020 Garces F, Mohr C, Zhang L, Huang CS, Chen Q, King C, Xu C, Wang Z. Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Reports. 30: 1714-1723.e6. PMID 32049005 DOI: 10.1016/j.celrep.2020.01.029   
2020 Ma Y, Ding Y, Song X, Ma X, Li X, Zhang N, Song Y, Sun Y, Shen Y, Zhong W, Hu LA, Ma Y, Zhang MY. Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Science Advances. 6: eaax7379. PMID 31998837 DOI: 10.1126/sciadv.aax7379   
2020 Chou CK, Liu YL, Chen YI, Huang PJ, Tsou PH, Chen CT, Lee HH, Wang YN, Hsu JL, Lee JF, Yankeelov TE, Kameoka J, Yeh HC, Hung MC. Digital Receptor Occupancy Assay in Quantifying On- and Off-Target Binding Affinities of Therapeutic Antibodies. Acs Sensors. PMID 32073836 DOI: 10.1021/acssensors.9b01736   
2020 Navaratnarajah CK, Generous AR, Yousaf I, Cattaneo R. Receptor-mediated cell entry of Paramyxoviruses: mechanisms, and consequences for tropism and pathogenesis. The Journal of Biological Chemistry. PMID 31949044 DOI: 10.1074/jbc.REV119.009961   
2020 Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I, Heilemann M. Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells. Science Signaling. 13. PMID 31937565 DOI: 10.1126/scisignal.aax5647   
2020 Moore E, Fraley ME, Bell IM, Burgey CS, White RB, Li CC, Regan CP, Danziger A, Stranieri Michener M, Hostetler E, Banerjee P, Salvatore C. Characterization of Ubrogepant: A Potent and Selective Antagonist of the Human Calcitonin Gene‒Related Peptide Receptor. The Journal of Pharmacology and Experimental Therapeutics. PMID 31992609 DOI: 10.1124/jpet.119.261065   
2020 Lewis R, Li J, McCormick PJ, L-H Huang C, Jeevaratnam K. Is the sigma-1 receptor a potential pharmacological target for cardiac pathologies? A systematic review. International Journal of Cardiology. Heart & Vasculature. 26: 100449. PMID 31909177 DOI: 10.1016/j.ijcha.2019.100449   
2020 Olivier JDA, Olivier B. Translational Studies in the Complex Role of Neurotransmitter Systems in Anxiety and Anxiety Disorders. Advances in Experimental Medicine and Biology. 1191: 121-140. PMID 32002926 DOI: 10.1007/978-981-32-9705-0_8   
2020 Wang J, Song X, Zhang D, Chen X, Li X, Sun Y, Li C, Song Y, Ding Y, Ren R, Harrington EH, Hu LA, Zhong W, Xu C, Huang X, et al. Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Research. PMID 32047270 DOI: 10.1038/s41422-020-0280-2   
2020 Singh V, Nemenman I. Universal Properties of Concentration Sensing in Large Ligand-Receptor Networks. Physical Review Letters. 124: 028101. PMID 32004056 DOI: 10.1103/PhysRevLett.124.028101   
2020 Gargiulo API, Acuña A, Gargiulo MML, Gargiulo ÁJM, Gargiulo MCJ, Baiardi GC, Mora S, Lafuente JV, Romanowicz E, Landa AI, Guevara MA, Gargiulo PÁ. Effects of Cycloleucine in the Nucleus Accumbens Septi on the Elevated plus Maze Test in Rats. Neuropsychobiology. 1-7. PMID 31927553 DOI: 10.1159/000505069   
2020 Li M, Liang P, Liu D, Yuan F, Chen GC, Zhang L, Liu Y, Liu H. Bombesin Receptor Subtype-3 in Human Diseases. Archives of Medical Research. 50: 463-467. PMID 31911345 DOI: 10.1016/j.arcmed.2019.11.004   
2020 Shao J, Talton J, Wang Y, Winner L, Hochhaus G. Quantitative Assessment of Pulmonary Targeting of Inhaled Corticosteroids Using Ex Vivo Receptor Binding Studies. The Aaps Journal. 22: 39. PMID 32002694 DOI: 10.1208/s12248-019-0404-0   
2020 Liang YL, Belousoff MJ, Zhao P, Koole C, Fletcher MM, Truong TT, Julita V, Christopoulos G, Xu HE, Zhang Y, Khoshouei M, Christopoulos A, Danev R, Sexton PM, Wootten D. Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Molecular Cell. PMID 32004469 DOI: 10.1016/j.molcel.2020.01.012   
2020 Ryu S, Howland A, Song B, Youn C, Song PI. Scavenger Receptor Class A to E Involved in Various Cancers. Chonnam Medical Journal. 56: 1-5. PMID 32021835 DOI: 10.4068/cmj.2020.56.1.1   
2020 Staus DP, Hu H, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G. Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc. Nature. PMID 31945772 DOI: 10.1038/s41586-020-1954-0   
2020 Silva ON, Franco OL, Neves BJ, Morais ÁCB, De Oliveira Neto JR, da Cunha LC, Naves LM, Pedrino GR, Costa EA, Fajemiroye JO. Involvement of the gabaergic, serotonergic and glucocorticoid mechanism in the anxiolytic-like effect of mastoparan-L. Neuropeptides. 102027. PMID 32059939 DOI: 10.1016/j.npep.2020.102027