Radda Rusinova, Ph.D. - Publications

Affiliations: 
2006 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
ionic channels, physiology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Maer AM, Rusinova R, Providence LL, Ingólfsson HI, Collingwood SA, Lundbæk JA, Andersen OS. Regulation of Gramicidin Channel Function Solely by Changes in Lipid Intrinsic Curvature. Frontiers in Physiology. 13: 836789. PMID 35350699 DOI: 10.3389/fphys.2022.836789  0.346
2021 Rusinova R, He C, Andersen OS. Mechanisms underlying drug-mediated regulation of membrane protein function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34753824 DOI: 10.1073/pnas.2113229118  0.353
2021 Ghovanloo MR, Choudhury K, Bandaru TS, Fouda MA, Rayani K, Rusinova R, Phaterpekar T, Nelkenbrecher K, Watkins AR, Poburko D, Thewalt J, Andersen OS, Delemotte L, Goodchild SJ, Ruben PC. Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity. The Journal of General Physiology. 153. PMID 33836525 DOI: 10.1085/jgp.202012701  0.302
2019 Doktorova M, Heberle FA, Marquardt D, Rusinova R, Sanford RL, Peyear TA, Katsaras J, Feigenson GW, Weinstein H, Andersen OS. Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles. Biophysical Journal. PMID 30755300 DOI: 10.1016/J.Bpj.2019.01.016  0.438
2019 Rusinova R, Andersen O. Drug Regulation of Ion Channel Function Involves Both Direct and Bilayer-Mediated Mechanisms Biophysical Journal. 116: 220a. DOI: 10.1016/J.Bpj.2018.11.1211  0.472
2018 Dockendorff C, Gandhi DM, Kimball IH, Eum KS, Rusinova R, Ingólfsson HI, Kapoor R, Peyear T, Dodge MW, Martin SF, Aldrich R, Andersen OS, Sack JT. Synthetic analogs of the snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT) reveal that lipid bilayer perturbation does not underlie its modulation of voltage-gated potassium channels. Biochemistry. PMID 29616558 DOI: 10.1021/Acs.Biochem.8B00292  0.561
2018 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Stopped-Flow Fluorometric Ion Flux Assay for Ligand-Gated Ion Channel Studies. Methods in Molecular Biology (Clifton, N.J.). 1684: 223-235. PMID 29058195 DOI: 10.1007/978-1-4939-7362-0_17  0.545
2017 O'Donnell JP, Cooley RB, Kelly CM, Miller K, Andersen OS, Rusinova R, Sondermann H. Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin. Structure (London, England : 1993). PMID 28602821 DOI: 10.1016/J.Str.2017.05.007  0.334
2017 Shore DM, Iaea DB, Rusinova R, Khelashvili G, Cuendet MA, Andersen OS, Maxfield FR, Weinstein H. Vectorial Cholesterol Transport by STARD4 is Mediated by Specific PIP 2 Membrane Composition Biophysical Journal. 112: 87a. DOI: 10.1016/J.Bpj.2016.11.511  0.34
2017 Peyear T, Rusinova R, Andersen OS. Examining the Translocation of Amphiphiles across Lipid Bilayers using a Gramicidin Channel-Based Fluorescent Assay Biophysical Journal. 112: 521a. DOI: 10.1016/J.Bpj.2016.11.2815  0.47
2017 Dockendorff C, Gandhi D, Kimball I, Eum KS, Rusinova R, Ingólfsson H, Kapoor R, Peyear T, Martin SF, Aldrich RW, Andersen OS, Sack J. Lipid Bilayer Perturbation by the Snail Toxin 6-Bromo-2-Mercaptotryptamine Dimer does not Account for its Modulation of Voltage-Gated Potassium Channels Biophysical Journal. 112: 246a-247a. DOI: 10.1016/J.Bpj.2016.11.1348  0.554
2017 Rusinova R, Andersen OS. Regulation of KcsA by Bilayer-Modifying Molecules Biophysical Journal. 112: 225a-226a. DOI: 10.1016/J.Bpj.2016.11.1243  0.493
2015 Rusinova R, Koeppe RE, Andersen OS. A general mechanism for drug promiscuity: Studies with amiodarone and other antiarrhythmics. The Journal of General Physiology. PMID 26573624 DOI: 10.1016/J.Bpj.2015.11.492  0.431
2015 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Calcium ions open a selectivity filter gate during activation of the MthK potassium channel. Nature Communications. 6: 8342. PMID 26395539 DOI: 10.1038/Ncomms9342  0.524
2015 Rusinova R, Koeppe RE, Andersen OS. A General Mechanism for Off-Target Effects: Studies with Amiodarone and other Antiarrhythmics Biophysical Journal. 108: 498a. DOI: 10.1016/J.Bpj.2014.11.2724  0.439
2014 Rusinova R, Kim DM, Nimigean CM, Andersen OS. Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay. Biophysical Journal. 106: 1070-8. PMID 24606931 DOI: 10.1016/J.Bpj.2014.01.027  0.562
2014 McCoy JG, Rusinova R, Kim DM, Kowal J, Banerjee S, Jaramillo Cartagena A, Thompson AN, Kolmakova-Partensky L, Stahlberg H, Andersen OS, Nimigean CM. A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics. The Journal of Biological Chemistry. 289: 9535-46. PMID 24515111 DOI: 10.1074/Jbc.M113.543389  0.564
2014 Posson DJ, Rusinova R, Andersen OS, Nimigean CM. Calcium-Dependent Gating in MthK K+ Channels Occurs at the Selectivity Filter Biophysical Journal. 106: 642a. DOI: 10.1016/J.Bpj.2013.11.3553  0.493
2013 Bruno MJ, Rusinova R, Gleason NJ, Koeppe RE, Andersen OS. Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation. Faraday Discussions. 161: 461-80; discussion 5. PMID 23805753 DOI: 10.1039/C2Fd20092A  0.441
2013 Rusinova R, Hobart EA, Koeppe RE, Andersen OS. Phosphoinositides alter lipid bilayer properties. The Journal of General Physiology. 141: 673-90. PMID 23712549 DOI: 10.1085/Jgp.201310960  0.525
2013 Rusinova R, Kim D, Nimigean C, Andersen OS. A New Assay for Ion Channel Function using Stopped Flow Spectrofluorometry Biophysical Journal. 104: 373a. DOI: 10.1016/J.Bpj.2012.11.2074  0.523
2011 Rusinova R, Herold KF, Sanford RL, Greathouse DV, Hemmings HC, Andersen OS. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery. The Journal of General Physiology. 138: 249-70. PMID 21788612 DOI: 10.1085/Jgp.201010529  0.534
2011 Michailidis IE, Rusinova R, Georgakopoulos A, Chen Y, Iyengar R, Robakis NK, Logothetis DE, Baki L. Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. Pflã¼Gers Archiv : European Journal of Physiology. 461: 387-97. PMID 21107857 DOI: 10.1007/S00424-010-0904-3  0.642
2010 Rusinova R, Herold KF, Koeppe RE, Hemmings H, Andersen OS. Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2612  0.561
2009 Geng X, Du XN, Rusinova R, Liu BY, Li F, Zhang X, Chen XJ, Logothetis DE, Zhang HL. Specificity of Gbetagamma signaling depends on Galpha subunit coupling with G-protein-sensitive K(+) channels. Pharmacology. 84: 82-90. PMID 19590257 DOI: 10.1159/000227772  0.637
2009 Rusinova R, Shen YM, Dolios G, Padovan J, Yang H, Kirchberger M, Wang R, Logothetis DE. Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunit. PflüGers Archiv : European Journal of Physiology. 458: 303-14. PMID 19151997 DOI: 10.1007/S00424-008-0628-9  0.616
2009 Rusinova R, Koeppe RE, Andersen OS. The Insulin-sensitizers Troglitazone And Rosiglitazone Alter Lipid Bilayer Properties Biophysical Journal. 96: 158a. DOI: 10.1016/J.Bpj.2008.12.720  0.562
2009 Baki L, Rodriguez AA, Rusinova R, Anderson CD, Logothetis DE. Hl-1 Cardiomyocytes As A Tool For The Study Of Regulation Of Kir3.1/Kir3.4 Channel Activity Biophysical Journal. 96: 465a. DOI: 10.1016/J.Bpj.2008.12.2393  0.64
2008 Rosenhouse-Dantsker A, Sui JL, Zhao Q, Rusinova R, Rodríguez-Menchaca AA, Zhang Z, Logothetis DE. A sodium-mediated structural switch that controls the sensitivity of Kir channels to PtdIns(4,5)P(2). Nature Chemical Biology. 4: 624-31. PMID 18794864 DOI: 10.1038/Nchembio.112  0.655
2007 Rusinova R, Mirshahi T, Logothetis DE. Specificity of Gbetagamma signaling to Kir3 channels depends on the helical domain of pertussis toxin-sensitive Galpha subunits. The Journal of Biological Chemistry. 282: 34019-30. PMID 17872944 DOI: 10.1074/Jbc.M704928200  0.628
2001 Tian L, Duncan RR, Hammond MS, Coghill LS, Wen H, Rusinova R, Clark AG, Levitan IB, Shipston MJ. Alternative splicing switches potassium channel sensitivity to protein phosphorylation. The Journal of Biological Chemistry. 276: 7717-20. PMID 11244090 DOI: 10.1074/jbc.C000741200  0.508
1995 Hasselbacher CA, Rusinova E, Waxman E, Rusinova R, Kohanski RA, Lam W, Guha A, Du J, Lin TC, Polikarpov I, Boys CWG, Nemerson Y, Konigsberg WH, Ross JBA. Environments of the four tryptophans in the extracellular domain of human tissue factor: Comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein Biophysical Journal. 69: 20-29. PMID 7669897 DOI: 10.1016/S0006-3495(95)79891-5  0.304
1995 Hasselbacher CA, Rusinova R, Rusinova E, Alexander Ross JB. Spectral enhancement of recombinant proteins with tryptophan analogs: The soluble domain of human tissue factor Techniques in Protein Chemistry. 6: 349-356. DOI: 10.1016/S1080-8914(06)80043-8  0.331
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