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Jaime H. Cheah, Ph.D. - Publications

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
Neurotransmitters
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12/35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Oberlick EM, Rees MG, Seashore-Ludlow B, Vazquez F, Nelson GM, Dharia NV, Weir BA, Tsherniak A, Ghandi M, Krill-Burger JM, Meyers RM, Wang X, Montgomery P, Root DE, Bieber JM, ... ... Cheah JH, et al. Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors. Cell Reports. 28: 2331-2344.e8. PMID 31461650 DOI: 10.1016/J.Celrep.2019.07.021  0.345
2018 Ferrer-Luna R, Ramkissoon SH, Ramkissoon LA, Pellton K, Schumacher SE, Lamothe R, Cheah JH, Haidar S, Kang YJ, Knoff DS, Maire CL, Olausson KH, Song W, Idbaih A, Rinne ML, et al. Abstract B077: Comprehensive molecular characterization and high-throughput chemical screening identifies genetic dependencies and molecular vulnerabilities in glioblastoma cell line models Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B077  0.315
2017 Ferrer-Luna R, Ramkissoon SH, Olausson KH, Ramkissoon LA, Schumacher S, Lamothe R, Cheah JH, Pellton K, Haidar S, Kang YJ, Paolella BR, Maire C, Song W, Meng A, Idbaih A, et al. Abstract 4974: Pharmacogenomic interactions in glioblastoma cell line models Cancer Research. 77: 4974-4974. DOI: 10.1158/1538-7445.Am2017-4974  0.307
2015 Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ. Discovery of a Small-Molecule Probe for V-ATPase Function. Journal of the American Chemical Society. 137: 5563-8. PMID 25860544 DOI: 10.1021/Jacs.5B02150  0.304
2015 Ferrer-Luna R, Ramkissoon SH, Ramkissoon LA, Lamothe R, Cheah JH, Schumacher SE, Haidar S, Clemons PA, Shamji A, Ligon KL, Beroukhim R. Abstract B66: Identification of genetic and non-genetic dependencies in glioblastoma cell lines targeted by small molecules Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B66  0.301
2014 Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR. Regulation of ferroptotic cancer cell death by GPX4. Cell. 156: 317-31. PMID 24439385 DOI: 10.1016/J.Cell.2013.12.010  0.349
2013 Choi BR, Bang S, Chen Y, Cheah JH, Kim SF. PKA modulates iron trafficking in the striatum via small GTPase, Rhes. Neuroscience. 253: 214-20. PMID 23999124 DOI: 10.1016/j.neuroscience.2013.08.043  0.599
2013 Basu A, Bodycombe NE, Cheah JH, Price EV, Liu K, Schaefer GI, Ebright RY, Stewart ML, Ito D, Wang S, Bracha AL, Liefeld T, Wawer M, Gilbert JC, Wilson AJ, et al. An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. 154: 1151-61. PMID 23993102 DOI: 10.1016/J.Cell.2013.08.003  0.311
2013 Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF. Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3582-7. PMID 23426685 DOI: 10.1523/Jneurosci.1497-12.2013  0.645
2006 Cheah JH, Kim SF, Hester LD, Clancy KW, Patterson SE, Papadopoulos V, Snyder SH. NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. Neuron. 51: 431-40. PMID 16908409 DOI: 10.1016/J.Neuron.2006.07.011  0.683
2005 Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, Ozeki Y, Takahashi M, Cheah JH, Tankou SK, Hester LD, Ferris CD, Hayward SD, Snyder SH, Sawa A. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nature Cell Biology. 7: 665-74. PMID 15951807 DOI: 10.1038/Ncb1268  0.59
2005 Huang Y, Man HY, Sekine-Aizawa Y, Han Y, Juluri K, Luo H, Cheah J, Lowenstein C, Huganir RL, Snyder SH. S-nitrosylation of N-ethylmaleimide sensitive factor mediates surface expression of AMPA receptors. Neuron. 46: 533-40. PMID 15944123 DOI: 10.1016/J.Neuron.2005.03.028  0.634
Low-probability matches (unlikely to be authored by this person)
2014 Adams DJ, Ito D, Rees MG, Seashore-Ludlow B, Puyang X, Ramos AH, Cheah JH, Clemons PA, Warmuth M, Zhu P, Shamji AF, Schreiber SL. NAMPT is the cellular target of STF-31-like small-molecule probes. Acs Chemical Biology. 9: 2247-54. PMID 25058389 DOI: 10.1021/Cb500347P  0.299
2015 Seashore-Ludlow B, Rees MG, Cheah JH, Cokol M, Price EV, Coletti ME, Jones V, Bodycombe NE, Soule CK, Gould J, Alexander B, Li A, Montgomery P, Wawer MJ, Kuru N, et al. Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset. Cancer Discovery. 5: 1210-23. PMID 26482930 DOI: 10.1158/2159-8290.Cd-15-0235  0.287
2016 Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weiwer M, An WF, ... ... Cheah JH, et al. Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-wide Selectivity and their Functional Effects. Acs Chemical Biology. PMID 27128528 DOI: 10.1021/Acschembio.6B00306  0.275
2016 Yard BD, Adams DJ, Chie EK, Tamayo P, Battaglia JS, Gopal P, Rogacki K, Pearson BE, Phillips J, Raymond DP, Pennell NA, Almeida F, Cheah JH, Clemons PA, Shamji A, et al. A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nature Communications. 7: 11428. PMID 27109210 DOI: 10.1038/Ncomms11428  0.254
2012 Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Carmody L, Yusuf RZ, Sykes DB, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Cheah J, et al. Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma Blood. 120: 571-571. DOI: 10.1182/Blood.V120.21.571.571  0.203
2007 Dinkova-Kostova AT, Cheah J, Samouilov A, Zweier JL, Bozak RE, Hicks RJ, Talalay P. Phenolic Michael reaction acceptors: Combined direct and indirect antioxidant defenses against electrophiles and oxidants Medicinal Chemistry. 3: 261-268. PMID 17504197 DOI: 10.2174/157340607780620680  0.186
2015 Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nature Chemical Biology. PMID 26656090 DOI: 10.1038/Nchembio.1986  0.185
2015 Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, et al. Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Cancer Discovery. 5: 154-67. PMID 25501949 DOI: 10.1158/2159-8290.Cd-14-0552  0.148
2023 Halvorsen SC, Benita Y, Hopton M, Hoppe B, Gunnlaugsson HO, Korgaonkar P, Vanderburg CR, Nielsen GP, Trepanowski N, Cheah JH, Frosch MP, Schwab JH, Rosenberg AE, Hornicek FJ, Sassi S. Transcriptional profiling supports the notochordal origin of chordoma and its dependence on a TGFΒ1-TBXT network. The American Journal of Pathology. PMID 36804377 DOI: 10.1016/j.ajpath.2023.01.014  0.145
2020 Olsson C, Payette JN, Cheah JH, Movassaghi M. Synthesis of Potent Cytotoxic Epidithiodiketopiperazines Designed for Derivatization. The Journal of Organic Chemistry. PMID 32126173 DOI: 10.1021/Acs.Joc.9B03371.S001  0.139
2018 Wong MY, Doan ND, DiChiara AS, Papa LJ, Cheah JH, Soule CK, Watson N, Hulleman JD, Shoulders MD. High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production. Biochemistry. PMID 29676157 DOI: 10.1021/Acs.Biochem.8B00378  0.137
2023 Abbott KL, Ali A, Casalena D, Do BT, Ferreira R, Cheah JH, Soule CK, Deik A, Kunchok T, Schmidt DR, Renner S, Honeder SE, Wu M, Chan SH, Tseyang T, et al. Screening in serum-derived medium reveals differential response to compounds targeting metabolism. Cell Chemical Biology. PMID 37689063 DOI: 10.1016/j.chembiol.2023.08.007  0.131
2023 Abbott KL, Ali A, Casalena D, Do BT, Ferreira R, Cheah JH, Soule CK, Deik A, Kunchok T, Schmidt DR, Renner S, Honeder SE, Wu M, Chan SH, Tseyang T, et al. Screening in serum-derived medium reveals differential response to compounds targeting metabolism. Biorxiv : the Preprint Server For Biology. PMID 36909640 DOI: 10.1101/2023.02.25.529972  0.13
2016 Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, et al. Integrated genetic and pharmacologic interrogation of rare cancers. Nature Communications. 7: 11987. PMID 27329820 DOI: 10.1038/Ncomms11987  0.124
2021 Hu G, Su Y, Kang BH, Fan Z, Dong T, Brown DR, Cheah J, Wittrup KD, Chen J. High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming. Nature Communications. 12: 773. PMID 33536439 DOI: 10.1038/s41467-021-21066-x  0.119
2023 Mead BE, Kummerlowe C, Liu N, Kattan WE, Cheng T, Cheah JH, Soule CK, Peters J, Lowder KE, Blainey PC, Hahn WC, Cleary B, Bryson B, Winter PS, Raghavan S, et al. Compressed phenotypic screens for complex multicellular models and high-content assays. Biorxiv : the Preprint Server For Biology. PMID 36747859 DOI: 10.1101/2023.01.23.525189  0.117
2019 Pompeo MM, Cheah JH, Movassaghi M. Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives. Journal of the American Chemical Society. PMID 31422662 DOI: 10.1021/Jacs.9B07397  0.101
2022 Katsumura S, Siddiqui N, Goldsmith MR, Cheah JH, Fujikawa T, Minegishi G, Yamagata A, Yabuki Y, Kobayashi K, Shirouzu M, Inagaki T, Huang TH, Musi N, Topisirovic I, Larsson O, et al. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure. Cell Metabolism. 34: 564-580.e8. PMID 35385705 DOI: 10.1016/j.cmet.2022.03.005  0.084
2022 Boehnke N, Straehla JP, Safford HC, Kocak M, Rees MG, Ronan M, Rosenberg D, Adelmann CH, Chivukula RR, Nabar N, Berger AG, Lamson NG, Cheah JH, Li H, Roth JA, et al. Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery. Science (New York, N.Y.). 377: eabm5551. PMID 35862544 DOI: 10.1126/science.abm5551  0.078
2019 Lee CX, Cheah JH, Soule CK, Ding H, Whittaker CA, Karhohs K, Burds AA, Subramanyam KS, Carpenter AE, Eisner BH, Cima MJ. Identification and local delivery of vasodilators for the reduction of ureteral contractions. Nature Biomedical Engineering. PMID 31792422 DOI: 10.1038/S41551-019-0482-4  0.075
2015 Adams TC, Payette JN, Cheah JH, Movassaghi M. Concise Total Synthesis of (+)-Luteoalbusins A and B. Organic Letters. 17: 4268-71. PMID 26336940 DOI: 10.1021/Acs.Orglett.5B02059  0.066
2024 Liu GW, Pickett MJ, Kuosmanen JLP, Ishida K, Madani WAM, White GN, Jenkins J, Park S, Feig VR, Jimenez M, Karavasili C, Lal NB, Murphy M, Lopes A, Morimoto J, ... ... Cheah JH, et al. Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics. Nature Materials. PMID 38413810 DOI: 10.1038/s41563-024-01811-5  0.053
2021 Reker D, Rybakova Y, Kirtane AR, Cao R, Yang JW, Navamajiti N, Gardner A, Zhang RM, Esfandiary T, L'Heureux J, von Erlach T, Smekalova EM, Leboeuf D, Hess K, Lopes A, ... ... Cheah JH, et al. Computationally guided high-throughput design of self-assembling drug nanoparticles. Nature Nanotechnology. PMID 33767382 DOI: 10.1038/s41565-021-00870-y  0.05
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