Florian T. Merkle, Ph.D. - Publications

2007 Neuroscience University of California, San Francisco, San Francisco, CA 
Neural stem cells

19/26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, et al. Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Science Translational Medicine. 8: 347ra93. PMID 27412785 DOI: 10.1126/scitranslmed.aaf6038  1
2015 Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus. Cell Reports. 11: 875-83. PMID 25937281 DOI: 10.1016/j.celrep.2015.04.007  1
2015 Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142: 1113-24. PMID 25725064 DOI: 10.1242/dev.117424  1
2015 Merkle FT, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier AF. Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England). 142: 633-43. PMID 25670790 DOI: 10.1242/dev.117978  1
2014 Kiskinis E, Sandoe J, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, et al. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 14: 781-95. PMID 24704492 DOI: 10.1016/j.stem.2014.03.004  1
2014 Merkle FT, Fuentealba LC, Sanders TA, Magno L, Kessaris N, Alvarez-Buylla A. Adult neural stem cells in distinct microdomains generate previously unknown interneuron types. Nature Neuroscience. 17: 207-14. PMID 24362763 DOI: 10.1038/nn.3610  1
2013 Suzuki N, Maroof AM, Merkle FT, Koszka K, Intoh A, Armstrong I, Moccia R, Davis-Dusenbery BN, Eggan K. The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD. Nature Neuroscience. 16: 1725-7. PMID 24185425 DOI: 10.1038/nn.3566  1
2013 Merkle FT, Eggan K. Modeling human disease with pluripotent stem cells: from genome association to function. Cell Stem Cell. 12: 656-68. PMID 23746975 DOI: 10.1016/j.stem.2013.05.016  1
2013 Maroof AM, Keros S, Tyson JA, Ying SW, Ganat YM, Merkle FT, Liu B, Goulburn A, Stanley EG, Elefanty AG, Widmer HR, Eggan K, Goldstein PA, Anderson SA, Studer L. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell. 12: 559-72. PMID 23642365 DOI: 10.1016/j.stem.2013.04.008  1
2013 Alvarez-Buylla A, Merkle F, Fuentealba L. Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 537-550. DOI: 10.1016/B978-0-12-397265-1.00096-4  1
2012 Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH. Regional astrocyte allocation regulates CNS synaptogenesis and repair. Science (New York, N.Y.). 337: 358-62. PMID 22745251 DOI: 10.1126/science.1222381  1
2012 Seeley WW, Merkle FT, Gaus SE, Craig AD, Allman JM, Hof PR, Economo CV. Distinctive neurons of the anterior cingulate and frontoinsular cortex: a historical perspective. Cerebral Cortex (New York, N.Y. : 1991). 22: 245-50. PMID 21653703 DOI: 10.1093/cercor/bhr005  1
2008 Alvarez-Buylla A, Kohwi M, Nguyen TM, Merkle FT. The heterogeneity of adult neural stem cells and the emerging complexity of their niche. Cold Spring Harbor Symposia On Quantitative Biology. 73: 357-65. PMID 19022766 DOI: 10.1101/sqb.2008.73.019  1
2008 Mirzadeh Z, Merkle FT, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell. 3: 265-78. PMID 18786414 DOI: 10.1016/j.stem.2008.07.004  1
2008 Lledo PM, Merkle FT, Alvarez-Buylla A. Origin and function of olfactory bulb interneuron diversity. Trends in Neurosciences. 31: 392-400. PMID 18603310 DOI: 10.1016/j.tins.2008.05.006  1
2007 Merkle FT, Mirzadeh Z, Alvarez-Buylla A. Mosaic organization of neural stem cells in the adult brain. Science (New York, N.Y.). 317: 381-4. PMID 17615304 DOI: 10.1126/science.1144914  1
2006 Merkle FT, Alvarez-Buylla A. Neural stem cells in mammalian development. Current Opinion in Cell Biology. 18: 704-9. PMID 17046226 DOI: 10.1016/j.ceb.2006.09.008  1
2005 Spassky N, Merkle FT, Flames N, Tramontin AD, García-Verdugo JM, Alvarez-Buylla A. Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10-8. PMID 15634762 DOI: 10.1523/JNEUROSCI.1108-04.2005  1
2004 Merkle FT, Tramontin AD, García-Verdugo JM, Alvarez-Buylla A. Radial glia give rise to adult neural stem cells in the subventricular zone. Proceedings of the National Academy of Sciences of the United States of America. 101: 17528-32. PMID 15574494 DOI: 10.1073/pnas.0407893101  1
Low-probability matches
2017 Merkle FT, Ghosh S, Kamitaki N, Mitchell J, Avior Y, Mello C, Kashin S, Mekhoubad S, Ilic D, Charlton M, Saphier G, Handsaker RE, Genovese G, Bar S, Benvenisty N, et al. Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations. Nature. PMID 28445466 DOI: 10.1038/nature22312  0.04
2016 Santos DP, Kiskinis E, Eggan K, Merkle FT. Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells. Current Protocols in Stem Cell Biology. 38: 5B.6.1-5B.6.60. PMID 27532820 DOI: 10.1002/cpsc.15  0.04
2020 Sonoyama T, Stadler LKJ, Zhu M, Keogh JM, Henning E, Hisama F, Kirwan P, Jura M, Blaszczyk BK, DeWitt DC, Brouwers B, Hyvönen M, Barroso I, Merkle FT, Appleyard SM, et al. Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities. Scientific Reports. 10: 9028. PMID 32493978 DOI: 10.1038/s41598-020-65531-x  0.01
2019 Razolli D, de Araújo T, Sant'Ana M, Kirwan P, Cintra D, Merkle F, Velloso L. POMC processing in the hypothalamus is directly regulated by saturated fat - implications for the development of obesity. Neuroendocrinology. PMID 31104058 DOI: 10.1159/000501023  0.01
2018 Kirwan P, Kay RG, Brouwers B, Herranz-Pérez V, Jura M, Larraufie P, Jerber J, Pembroke J, Bartels T, White A, Gribble FM, Reimann F, Farooqi IS, O'Rahilly S, Merkle FT. Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis. Molecular Metabolism. PMID 30201275 DOI: 10.1016/j.molmet.2018.08.006  0.01
2018 Heeley N, Kirwan P, Darwish T, Arnaud M, Evans ML, Merkle FT, Reimann F, Gribble FM, Blouet C. Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights. Molecular Metabolism. PMID 29439854 DOI: 10.1016/j.molmet.2018.01.021  0.01
2017 Kirwan P, Jura M, Merkle FT. Generation and Characterization of Functional Human Hypothalamic Neurons. Current Protocols in Neuroscience. 81: 3.33.1-3.33.24. PMID 29064566 DOI: 10.1002/cpns.40  0.01
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