Charles W. Bugg, Ph.D. - Publications
Affiliations: | 2011 | Biochemistry and Molecular Biophysics | California Institute of Technology, Pasadena, CA |
Year | Citation | Score | |||
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2012 | Bugg CW, Isas JM, Fischer T, Patterson PH, Langen R. Structural features and domain organization of huntingtin fibrils. The Journal of Biological Chemistry. 287: 31739-46. PMID 22801429 DOI: 10.1074/Jbc.M112.353839 | 0.515 | |||
2011 | Southwell AL, Bugg CW, Kaltenbach LS, Dunn D, Butland S, Weiss A, Paganetti P, Lo DC, Patterson PH. Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1. Plos One. 6: e16676. PMID 21304966 DOI: 10.1371/Journal.Pone.0016676 | 0.471 | |||
2008 | Southwell AL, Khoshnan A, Dunn DE, Bugg CW, Lo DC, Patterson PH. Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9013-20. PMID 18768695 DOI: 10.1523/Jneurosci.2747-08.2008 | 0.482 | |||
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