| Year |
Citation |
Score |
| 2020 |
Wong P, Ho WY, Yen YC, Sanford E, Ling SC. The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43. Neurobiology of Aging. 92: 43-60. PMID 32422502 DOI: 10.1016/J.Neurobiolaging.2020.03.019 |
0.352 |
|
| 2019 |
Ho WY, Chang JC, Tyan SH, Yen YC, Lim K, Tan BSY, Ong J, Tucker-Kellogg G, Wong P, Koo E, Ling SC. FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits. Human Molecular Genetics. PMID 31509188 DOI: 10.1093/Hmg/Ddz217 |
0.329 |
|
| 2019 |
Ho WY, Ling SC. Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis. Autophagy. 1-3. PMID 31230528 DOI: 10.1080/15548627.2019.1633162 |
0.396 |
|
| 2019 |
Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. PMID 30669939 DOI: 10.1080/15548627.2019.1569441 |
0.333 |
|
| 2018 |
Wang J, Ho WY, Lim K, Feng J, Tucker-Kellogg G, Nave KA, Ling SC. Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination. Proceedings of the National Academy of Sciences of the United States of America. PMID 30373824 DOI: 10.1073/Pnas.1809821115 |
0.305 |
|
| 2018 |
López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Ling SC, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. PMID 30344044 DOI: 10.1016/J.Neuron.2018.09.044 |
0.39 |
|
| 2018 |
Lu W, Lakonishok M, Serpinskaya AS, Kirchenbüechler D, Ling SC, Gelfand VI. Ooplasmic flow cooperates with transport and anchorage in oocyte posterior determination. The Journal of Cell Biology. PMID 30037924 DOI: 10.1083/Jcb.201709174 |
0.617 |
|
| 2018 |
Ling SC. Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions. Neural Plasticity. 2018: 8413496. PMID 29755516 DOI: 10.1155/2018/8413496 |
0.412 |
|
| 2018 |
Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, et al. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. Acta Neuropathologica. PMID 29725819 DOI: 10.1007/S00401-018-1852-9 |
0.406 |
|
| 2015 |
Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathologica Communications. 3: 36. PMID 26108367 DOI: 10.1186/S40478-015-0212-4 |
0.356 |
|
| 2013 |
Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E4530-9. PMID 24170860 DOI: 10.1073/Pnas.1318835110 |
0.33 |
|
| 2013 |
Ling SC, Polymenidou M, Cleveland DW. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron. 79: 416-38. PMID 23931993 DOI: 10.1016/J.Neuron.2013.07.033 |
0.362 |
|
| 2013 |
Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, et al. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. The Journal of Biological Chemistry. 288: 25266-74. PMID 23867462 DOI: 10.1074/Jbc.M113.492017 |
0.419 |
|
| 2013 |
Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America. 110: E736-45. PMID 23382207 DOI: 10.1073/Pnas.1222809110 |
0.429 |
|
| 2012 |
Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nature Neuroscience. 15: 1488-97. PMID 23023293 DOI: 10.1038/Nn.3230 |
0.354 |
|
| 2011 |
Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, et al. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nature Neuroscience. 14: 459-68. PMID 21358643 DOI: 10.1038/Nn.2779 |
0.399 |
|
| 2010 |
Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proceedings of the National Academy of Sciences of the United States of America. 107: 13318-23. PMID 20624952 DOI: 10.1073/Pnas.1008227107 |
0.408 |
|
| 2007 |
Kim H, Ling SC, Rogers GC, Kural C, Selvin PR, Rogers SL, Gelfand VI. Microtubule binding by dynactin is required for microtubule organization but not cargo transport. The Journal of Cell Biology. 176: 641-51. PMID 17325206 DOI: 10.1083/Jcb.200608128 |
0.62 |
|
| 2005 |
Angenstein F, Evans AM, Ling SC, Settlage RE, Ficarro S, Carrero-Martinez FA, Shabanowitz J, Hunt DF, Greenough WT. Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. The Journal of Biological Chemistry. 280: 6496-503. PMID 15596439 DOI: 10.1074/Jbc.M412742200 |
0.565 |
|
| 2004 |
Ling SC, Fahrner PS, Greenough WT, Gelfand VI. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proceedings of the National Academy of Sciences of the United States of America. 101: 17428-33. PMID 15583137 DOI: 10.1073/pnas.0408114101 |
0.64 |
|
| 2002 |
Angenstein F, Evans AM, Settlage RE, Moran ST, Ling SC, Klintsova AY, Shabanowitz J, Hunt DF, Greenough WT. A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8827-37. PMID 12388589 DOI: 10.1523/Jneurosci.22-20-08827.2002 |
0.566 |
|
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