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Erin H. Norris, Ph.D. - Publications

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cajamarca SA, Norris EH, van der Weerd L, Strickland S, Ahn HJ. Cerebral amyloid angiopathy-linked β-amyloid mutations promote cerebral fibrin deposits via increased binding affinity for fibrinogen. Proceedings of the National Academy of Sciences of the United States of America. PMID 32518112 DOI: 10.1073/Pnas.1921327117  0.358
2020 Singh PK, Chen ZL, Ghosh D, Strickland S, Norris EH. Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients. Neurobiology of Disease. 104833. PMID 32173555 DOI: 10.1016/J.Nbd.2020.104833  0.34
2019 Chen ZL, Singh P, Wong J, Horn K, Strickland S, Norris EH. An antibody against HK blocks Alzheimer's disease peptide β-amyloid-induced bradykinin release in human plasma. Proceedings of the National Academy of Sciences of the United States of America. PMID 31659032 DOI: 10.1073/Pnas.1914831116  0.33
2019 Cortes-Canteli M, Kruyer A, Fernandez-Nueda I, Marcos-Diaz A, Ceron C, Richards AT, Jno-Charles OC, Rodriguez I, Callejas S, Norris EH, Sanchez-Gonzalez J, Ruiz-Cabello J, Ibanez B, Strickland S, Fuster V. Long-Term Dabigatran Treatment Delays Alzheimer's Disease Pathogenesis in the TgCRND8 Mouse Model. Journal of the American College of Cardiology. 74: 1910-1923. PMID 31601371 DOI: 10.1016/J.Jacc.2019.07.081  0.353
2019 Ahn HJ, Baker SK, Norris EH, Strickland S. Inflaming the Brain. Neuron. 101: 991-993. PMID 30897363 DOI: 10.1016/J.Neuron.2019.03.007  0.332
2019 Farfara D, Feierman E, Richards A, Revenko AS, MacLeod RA, Norris EH, Strickland S. Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits. Glia. PMID 30882931 DOI: 10.1002/Glia.23611  0.303
2018 Yamamoto-Imoto H, Zamolodchikov D, Chen ZL, Bourne SL, Rizvi S, Singh P, Norris EH, Weis-Garcia F, Strickland S. A novel detection method of cleaved plasma high-molecular-weight kininogen reveals its correlation with Alzheimer's pathology and cognitive impairment. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 480-489. PMID 30310850 DOI: 10.1016/J.Dadm.2018.06.008  0.322
2018 Baker SK, Chen ZL, Norris EH, Revenko AS, MacLeod AR, Strickland S. Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254165 DOI: 10.1073/Pnas.1811172115  0.374
2018 Suidan GL, Singh PK, Patel-Hett S, Chen ZL, Volfson D, Yamamoto-Imoto H, Norris EH, Bell RD, Strickland S. Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability. Blood Advances. 2: 954-963. PMID 29700007 DOI: 10.1182/Bloodadvances.2018017798  0.337
2018 Singh PK, Kawasaki M, Berk-Rauch HE, Nishida G, Yamasaki T, Foley MA, Norris EH, Strickland S, Aso K, Ahn HJ. Aminopyrimidine class aggregation inhibitor effectively blocks AΒ-fibrinogen interaction and AΒ-induced contact system activation. Biochemistry. PMID 29394041 DOI: 10.1021/Acs.Biochem.7B01214  0.378
2017 Ahn HJ, Chen ZL, Zamolodchikov D, Norris EH, Strickland S. Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease. Current Opinion in Hematology. PMID 28661939 DOI: 10.1097/Moh.0000000000000368  0.327
2017 Chen ZL, Revenko AS, Singh P, MacLeod AR, Norris EH, Strickland S. Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer's disease mice. Blood. PMID 28242605 DOI: 10.1182/Blood-2016-11-753202  0.359
2016 Chung YC, Kruyer A, Yao Y, Feierman E, Richards A, Strickland S, Norris EH. Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the Aβ-fibrinogen interaction. Journal of Thrombosis and Haemostasis : Jth. PMID 27090576 DOI: 10.1111/Jth.13340  0.366
2015 Kruyer A, Soplop N, Strickland S, Norris EH. Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease. Hypertension. 66: 175-82. PMID 25941345 DOI: 10.1161/Hypertensionaha.115.05524  0.323
2015 Cortes-Canteli M, Mattei L, Richards AT, Norris EH, Strickland S. Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration. Neurobiology of Aging. 36: 608-17. PMID 25475538 DOI: 10.1016/J.Neurobiolaging.2014.10.030  0.399
2014 Ahn HJ, Fraser Glickman J, Poon KL, Zamolodchikov D, Jno-Charles OC, Norris EH, Strickland S. A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice Journal of Experimental Medicine. 211: 1049-1062. PMID 24821909 DOI: 10.1084/Jem.20131751  0.365
2014 Yao Y, Chen ZL, Norris EH, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nature Communications. 5: 3413. PMID 24583950 DOI: 10.1038/Ncomms4413  0.316
2013 Hultman K, Strickland S, Norris EH. The APOE ε4/ε4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients Journal of Cerebral Blood Flow and Metabolism. 33: 1251-1258. PMID 23652625 DOI: 10.1038/Jcbfm.2013.76  0.357
2013 Chung YC, Norris E, Strickland S. P4-341: Hyperhomocysteinemia exacerbates cerebral amyloid angiopathy and cognitive decline through the beta-amyloid and fibrinogen interaction in Alzheimer's disease Alzheimer's & Dementia. 9: P856-P857. DOI: 10.1016/J.Jalz.2013.08.175  0.327
2012 Cortes-Canteli M, Zamolodchikov D, Ahn HJ, Strickland S, Norris EH. Fibrinogen and altered hemostasis in Alzheimer's disease Journal of Alzheimer's Disease. 32: 599-608. PMID 22869464 DOI: 10.3233/Jad-2012-120820  0.38
2010 Ahn HJ, Zamolodchikov D, Cortes-Canteli M, Norris EH, Glickman JF, Strickland S. Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. Proceedings of the National Academy of Sciences of the United States of America. 107: 21812-7. PMID 21098282 DOI: 10.1073/Pnas.1010373107  0.365
2010 Cortes-Canteli M, Paul J, Norris EH, Bronstein R, Ahn HJ, Zamolodchikov D, Bhuvanendran S, Fenz KM, Strickland S. Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease. Neuron. 66: 695-709. PMID 20547128 DOI: 10.1016/J.Neuron.2010.05.014  0.393
2008 Park L, Zhou P, Pitstick R, Capone C, Anrather J, Norris EH, Younkin L, Younkin S, Carlson G, McEwen BS, Iadecola C. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 1347-52. PMID 18202172 DOI: 10.1073/Pnas.0711568105  0.387
2007 Norris EH, Uryu K, Leight S, Giasson BI, Trojanowski JQ, Lee VM. Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model. The American Journal of Pathology. 170: 658-66. PMID 17255333 DOI: 10.2353/Ajpath.2007.060359  0.707
2006 Uryu K, Richter-Landsberg C, Welch W, Sun E, Goldbaum O, Norris EH, Pham CT, Yazawa I, Hilburger K, Micsenyi M, Giasson BI, Bonini NM, Lee VM, Trojanowski JQ. Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies. The American Journal of Pathology. 168: 947-61. PMID 16507910 DOI: 10.2353/Ajpath.2006.050770  0.694
2005 Mishizen-Eberz AJ, Norris EH, Giasson BI, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. Biochemistry. 44: 7818-29. PMID 15909996 DOI: 10.1021/Bi047846Q  0.713
2005 Norris EH, Giasson BI. Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders. Antioxidants & Redox Signaling. 7: 672-84. PMID 15890012 DOI: 10.1089/Ars.2005.7.672  0.675
2005 Norris EH, Giasson BI, Hodara R, Xu S, Trojanowski JQ, Ischiropoulos H, Lee VM. Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. The Journal of Biological Chemistry. 280: 21212-9. PMID 15817478 DOI: 10.1074/Jbc.M412621200  0.684
2004 Hodara R, Norris EH, Giasson BI, Mishizen-Eberz AJ, Lynch DR, Lee VM, Ischiropoulos H. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. The Journal of Biological Chemistry. 279: 47746-53. PMID 15364911 DOI: 10.1074/Jbc.M408906200  0.706
2004 Norris EH, Giasson BI, Lee VM. Alpha-synuclein: normal function and role in neurodegenerative diseases. Current Topics in Developmental Biology. 60: 17-54. PMID 15094295 DOI: 10.1016/S0070-2153(04)60002-0  0.702
2004 Norris EH, Giasson BI, Xu S, Hodara R, Trojanowski JQ, Ischiropoulos H, Lee V. P1-302 Implications of dopamine-induced modificationsof alpha-synuclein protein in the pathogenesis of Parkinson's disease Neurobiology of Aging. 25: S182. DOI: 10.1016/S0197-4580(04)80615-8  0.676
2003 Norris EH, Giasson BI, Ischiropoulos H, Lee VM. Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications. The Journal of Biological Chemistry. 278: 27230-40. PMID 12857790 DOI: 10.1074/Jbc.M212436200  0.695
2001 Paxinou E, Chen Q, Weisse M, Giasson BI, Norris EH, Rueter SM, Trojanowski JQ, Lee VM, Ischiropoulos H. Induction of alpha-synuclein aggregation by intracellular nitrative insult. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8053-61. PMID 11588178  0.696
2001 Paxinou E, Chen Q, Weisse M, Giasson BI, Norris EH, Rueter SM, Trojanowski JQ, Lee VM, Ischiropoulos H. Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult The Journal of Neuroscience. 21: 8053-8061. DOI: 10.1523/Jneurosci.21-20-08053.2001  0.543
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