James H. Soper, Ph.D. - Publications
Affiliations: | 2008 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
tau, dementia, neurodegenerationYear | Citation | Score | |||
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2012 | Soper JH, Sugiyama S, Herbst-Robinson K, James MJ, Wang X, Trojanowski JQ, Smith AB, Lee VM, Ballatore C, Brunden KR. Brain-penetrant tetrahydronaphthalene thromboxane A2-prostanoid (TP) receptor antagonists as prototype therapeutics for Alzheimer's disease. Acs Chemical Neuroscience. 3: 928-40. PMID 23173073 DOI: 10.1021/Cn3000795 | 0.428 | |||
2011 | Ballatore C, Soper JH, Piscitelli F, James M, Huang L, Atasoylu O, Huryn DM, Trojanowski JQ, Lee VM, Brunden KR, Smith AB. Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists. Journal of Medicinal Chemistry. 54: 6969-83. PMID 21863799 DOI: 10.1021/Jm200980U | 0.379 | |||
2011 | Lim Y, Kehm VM, Lee EB, Soper JH, Li C, Trojanowski JQ, Lee VM. α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10076-87. PMID 21734300 DOI: 10.1523/Jneurosci.0618-11.2011 | 0.456 | |||
2011 | Soper JH, Kehm V, Burd CG, Bankaitis VA, Lee VM. Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis. Journal of Molecular Neuroscience : Mn. 43: 391-405. PMID 20890676 DOI: 10.1007/S12031-010-9455-5 | 0.599 | |||
2008 | Soper JH, Roy S, Stieber A, Lee E, Wilson RB, Trojanowski JQ, Burd CG, Lee VM. Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae. Molecular Biology of the Cell. 19: 1093-103. PMID 18172022 DOI: 10.1091/Mbc.E07-08-0827 | 0.538 | |||
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