Tinatin I. Brelidze, Ph.D. - Publications

Affiliations: 
2003 University of Miami, Coral Gables, FL 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang ZJ, Blanco I, Hayoz S, Brelidze TI. The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms. The Journal of Biological Chemistry. PMID 32341127 DOI: 10.1074/Jbc.Ra120.013281  0.616
2020 Wang ZJ, Soohoo SM, Tiwari PB, Piszczek G, Brelidze TI. Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity. The Journal of Biological Chemistry. PMID 32047112 DOI: 10.1074/Jbc.Ra119.012377  0.56
2019 Wang ZJ, Tiwari PB, Üren A, Brelidze TI. Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels. Bmc Pharmacology & Toxicology. 20: 42. PMID 31315662 DOI: 10.1186/S40360-019-0324-8  0.569
2019 Brelidze TI. N- and C-terminal interactions in KCNH channels: The spotlight on the intrinsic ligand. The Journal of General Physiology. PMID 30782602 DOI: 10.1085/Jgp.201812313  0.611
2019 Islas LD, Muallem S, Brelidze T. Decision letter: Agonist-specific voltage-dependent gating of lysosomal two-pore Na+ channels Elife. DOI: 10.7554/Elife.51423.Sa1  0.564
2019 Tiwari P, Uren A, Brelidze TI. Identifying Novel KCNH Channel Ligands with Surface Plasmon Resonance Method Biophysical Journal. 116: 248a. DOI: 10.1016/J.Bpj.2018.11.1356  0.459
2018 Hayoz S, Tiwari PB, Piszczek G, Üren A, Brelidze TI. Investigating Cyclic Dinucleotide Binding to HCN Channels by Surface Plasmon Resonance and Isothermal Calorimetry Biophysical Journal. 114: 120a. DOI: 10.1016/J.Bpj.2017.11.686  0.397
2017 Hayoz S, Tiwari PB, Piszczek G, Üren A, Brelidze TI. Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance. Plos One. 12: e0185359. PMID 28950029 DOI: 10.1371/Journal.Pone.0185359  0.567
2017 Tiwari P, Üren A, Brelidze TI. Investigating Ligand Binding to HCN Channels by Surface Plasmon Resonance Biophysical Journal. 112: 40a. DOI: 10.1016/J.Bpj.2016.11.252  0.4
2013 Carlson AE, Rosenbaum JC, Brelidze TI, Klevit RE, Zagotta WN. Flavonoid regulation of HCN2 channels. The Journal of Biological Chemistry. 288: 33136-45. PMID 24085296 DOI: 10.1074/Jbc.M113.501759  0.619
2013 Brelidze TI, Gianulis EC, DiMaio F, Trudeau MC, Zagotta WN. Structure of the C-terminal region of an ERG channel and functional implications. Proceedings of the National Academy of Sciences of the United States of America. 110: 11648-53. PMID 23801759 DOI: 10.1073/Pnas.1306887110  0.622
2013 Carlson AE, Brelidze TI, Zagotta WN. Flavonoid regulation of EAG1 channels. The Journal of General Physiology. 141: 347-58. PMID 23440277 DOI: 10.1085/Jgp.201210900  0.64
2013 Brelidze TI, DiMaio F, Trudeau MC, Zagotta WN. Structure of the C-Terminal Region of an ERG Channel and Functional Implications for Long-QT Syndrome Biophysical Journal. 104: 356a. DOI: 10.1016/J.Bpj.2012.11.1978  0.597
2012 Brelidze TI, Carlson AE, Sankaran B, Zagotta WN. Structure of the carboxy-terminal region of a KCNH channel. Nature. 481: 530-3. PMID 22230959 DOI: 10.1038/Nature10735  0.617
2012 Brelidze TI, Carlson AE, Sankaran B, Zagotta WN. Structure of the C-Terminal Region of a KCNH Channel Biophysical Journal. 102: 37a. DOI: 10.1016/J.Bpj.2011.11.230  0.634
2012 Carlson AE, Brelidze TI, Zagotta WN. Fisetin Regulation of HCN2 and Eag1 Channels Reveals Conserved Gating Mechanisms Biophysical Journal. 102: 330a. DOI: 10.1016/J.Bpj.2011.11.1810  0.637
2011 Brelidze TI, Zagotta WN. Exploring Ligand Regulation of Ion Channels in the EAG Family Biophysical Journal. 100: 103a. DOI: 10.1016/J.Bpj.2010.12.771  0.512
2010 Brelidze TI, Carlson AE, Davies DR, Stewart LJ, Zagotta WN. Identifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screen. Plos One. 5. PMID 20824064 DOI: 10.1371/Journal.Pone.0012523  0.543
2010 Carlson AE, Brelidze TI, Davies DR, Zagotta W. Flavonoids Regulate Eag1 Channels Biophysical Journal. 98: 1a. DOI: 10.1016/J.Bpj.2009.11.037  0.598
2009 Brelidze TI, Carlson AE, Zagotta WN. Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods. The Journal of Biological Chemistry. 284: 27989-97. PMID 19671703 DOI: 10.1074/Jbc.M109.016337  0.612
2006 Zhang Y, Niu X, Brelidze TI, Magleby KL. Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics. The Journal of General Physiology. 128: 185-202. PMID 16847096 DOI: 10.1085/Jgp.200609493  0.659
2005 Brelidze TI, Magleby KL. Probing the geometry of the inner vestibule of BK channels with sugars. The Journal of General Physiology. 126: 105-21. PMID 16043773 DOI: 10.1085/Jgp.200509286  0.71
2004 Brelidze TI, Magleby KL. Protons block BK channels by competitive inhibition with K+ and contribute to the limits of unitary currents at high voltages. The Journal of General Physiology. 123: 305-19. PMID 14981139 DOI: 10.1085/Jgp.200308951  0.659
2003 Brelidze TI, Niu X, Magleby KL. A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification. Proceedings of the National Academy of Sciences of the United States of America. 100: 9017-22. PMID 12843404 DOI: 10.1073/Pnas.1532257100  0.73
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