John J. Millichap, MD - Related publications

Northwestern University Feinberg School of Medicine, Chicago, IL, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Kayser S, Temperini P, Poulie CBM, Staudt M, Nielsen B, Pickering DS, Bunch L. A Diversity Oriented Synthesis Approach to New 2,3--Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate Receptors. Acs Chemical Neuroscience. PMID 32069018 DOI: 10.1021/acschemneuro.0c00005   
2020 Jégouzo SAF, Nelson C, Hardwick T, Wong STA, Lau NKK, Neoh GKE, Castellanos-Rueda R, Huang Z, Mignot B, Hirdaramani A, Howitt A, Frewin K, Shen Z, Fox RJ, Wong R, et al. Mammalian lectin arrays for screening host-microbe interactions. The Journal of Biological Chemistry. PMID 32094229 DOI: 10.1074/jbc.RA120.012783   
2020 Su Z, Wu Y. A Systematic Test of Receptor Binding Kinetics for Ligands in Tumor Necrosis Factor Superfamily by Computational Simulations. International Journal of Molecular Sciences. 21. PMID 32150842 DOI: 10.3390/ijms21051778   
2020 Qu L, Wang J, Hou T, Zhou H, Wang Z, Zhang X, Liang X. Systematic characterization of AT1 receptor antagonists with label-free dynamic mass redistribution assays. Journal of Pharmacological and Toxicological Methods. 106682. PMID 32087363 DOI: 10.1016/j.vascn.2020.106682   
2020 Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, et al. Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science (New York, N.Y.). 367: 643-652. PMID 32029621 DOI: 10.1126/science.aaw3242   
2020 Underwood MD, Bakalian MJ, Johnson VL, Kassir SA, Ellis SP, Mann JJ, Arango V. Less NMDA Receptor Binding in Dorsolateral Prefrontal Cortex and Anterior Cingulate Cortex Associated with Reported Early Life Adversity but Not Suicide. The International Journal of Neuropsychopharmacology. PMID 32060512 DOI: 10.1093/ijnp/pyaa009   
2020 Tong L, Li W, Lo MM, Gao X, Wai JM, Rudd MT, Tellers DM, Joshi A, Zeng Z, Miller P, Salinas C, Riffel K, Haley HD, Purcell M, Holahan M, et al. Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4 Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases. Journal of Medicinal Chemistry. PMID 32101422 DOI: 10.1021/acs.jmedchem.9b01406   
2020 Jakubik J, El-Fakahany EE. Current Advances in Allosteric Modulation of Muscarinic Receptors. Biomolecules. 10. PMID 32085536 DOI: 10.3390/biom10020325   
2020 Jaremko W, Huang Z, Karl N, Pierce VD, Lynch J, Niu L. A kainate receptor-selective RNA aptamer. The Journal of Biological Chemistry. PMID 32161119 DOI: 10.1074/jbc.RA119.011649   
2020 Smart K, Gallezot JD, Nabulsi N, Labaree D, Zheng MQ, Huang Y, Carson RE, Hillmer AT, Worhunsky PD. Separating dopamine D and D receptor sources of [C]-(+)-PHNO binding potential: Independent component analysis of competitive binding. Neuroimage. 116762. PMID 32201327 DOI: 10.1016/j.neuroimage.2020.116762   
2020 Curry SH, Marler M. Effects of ecgonine methyl ester on cognition in scopolamine-impaired and aged rats. Psychopharmacology. PMID 32034448 DOI: 10.1007/s00213-020-05460-9   
2020 Huang BX, Hu X, Kwon HS, Fu C, Lee JW, Southall N, Marugan J, Kim HY. Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding. Communications Biology. 3: 109. PMID 32144388 DOI: 10.1038/s42003-020-0831-6   
2020 Pan Q, Wang J, Gao Y, Wang Q, Cui H, Liu C, Qi X, Zhang Y, Wang Y, Li K, Gao L, Liu A, Wang X. Identification of chicken CAR homology as a cellular receptor for the emerging highly pathogenic fowl adenovirus 4 via unique binding mechanism. Emerging Microbes & Infections. 9: 586-596. PMID 32174269 DOI: 10.1080/22221751.2020.1736954   
2020 Park J, Langmead CJ, Riddy DM. New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery. Acs Pharmacology & Translational Science. 3: 88-106. PMID 32259091 DOI: 10.1021/acsptsci.9b00075   
2020 Rani K, Tyagi M, Mazumder M, Singh A, Shanmugam A, Dalal K, Pillai M, Samudrala G, Kumar S, Srinivasan A. Accelerated identification of serine racemase inhibitor from Centella asiatica. Scientific Reports. 10: 4640. PMID 32170206 DOI: 10.1038/s41598-020-61494-1   
2020 Jatczak-Śliwa M, Kisiel M, Czyzewska MM, Brodzki M, Mozrzymas JW. GABA Receptor βE155 Residue Located at the Agonist-Binding Site Is Involved in the Receptor Gating. Frontiers in Cellular Neuroscience. 14: 2. PMID 32116555 DOI: 10.3389/fncel.2020.00002   
2020 Shu Y, Diamond TL, Hershey JC, Huang S, Magliaro BC, O'Brien JA, Schlegel KS, Puri V, Uebele VN, Uslaner JM, Wang C, Converso A. Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models. Bioorganic & Medicinal Chemistry Letters. 127066. PMID 32173198 DOI: 10.1016/j.bmcl.2020.127066   
2020 Shalabi AR, Yu Z, Zhou X, Jounaidi Y, Chen H, Dai J, Kent DE, Feng HJ, Forman SA, Cohen JB, Bruzik KS, Miller KW. A potent photoreactive general anesthetic with novel binding site selectivity for GABA receptors. European Journal of Medicinal Chemistry. 194: 112261. PMID 32247113 DOI: 10.1016/j.ejmech.2020.112261   
2020 Takahashi M, Ubukata O, Homma T, Asoh Y, Honzumi M, Hayashi N, Saito K, Tsuruoka H, Aoki K, Hanzawa H. Crystal structure of the mineralocorticoid receptor ligand-binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS-3150). Febs Letters. PMID 31991486 DOI: 10.1002/1873-3468.13746   
2020 Graham B, Shaw MA, Hope IA. Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects on Neuro-Muscular Function. Frontiers in Genetics. 11: 37. PMID 32174957 DOI: 10.3389/fgene.2020.00037   
2020 Kashimoto T, Sugiyama H, Kawamidori K, Yamazaki K, Kado T, Matsuda K, Kodama T, Mukai T, Ueno S. Vibiro vulnificus hemolysin associates with gangliosides. Bmc Microbiology. 20: 69. PMID 32228455 DOI: 10.1186/s12866-020-01755-1   
2020 Yuen H, Hung A, Yang AWH, Lenon GB. Mechanisms of Action of Cassiae Semen for Weight Management: A Computational Molecular Docking Study of Serotonin Receptor 5-HT2C. International Journal of Molecular Sciences. 21. PMID 32079105 DOI: 10.3390/ijms21041326   
2020 Lee HW, Sharma P, Janssen BJ, Drummond RSM, Luo Z, Hamiaux C, Collier T, Allison JR, Newcomb RD, Snowden KC. Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners. The Journal of Biological Chemistry. PMID 32071083 DOI: 10.1074/jbc.RA119.011509   
2020 Merkel PA, Jayne DR, Wang C, Hillson J, Bekker P. A randomized, double-blind, active-controlled, Phase 3 study to evaluate the safety and efficacy of avacopan, a C5a receptor inhibitor, in patients with ANCA-associated vasculitis treated concomitantly with rituximab or cyclophosphamide/ azathioprine. Jmir Research Protocols. PMID 32088663 DOI: 10.2196/16664   
2020 Shang J, Wan Y, Liu C, Yount B, Gully K, Yang Y, Auerbach A, Peng G, Baric R, Li F. Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry. Plos Pathogens. 16: e1008392. PMID 32150576 DOI: 10.1371/journal.ppat.1008392   
2020 Wang R, Qi X, Schmiege P, Coutavas E, Li X. Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments. Science Advances. 6: eaaz1466. PMID 32095534 DOI: 10.1126/sciadv.aaz1466   
2020 Garces F, Mohr C, Zhang L, Huang CS, Chen Q, King C, Xu C, Wang Z. Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Reports. 30: 1714-1723.e6. PMID 32049005 DOI: 10.1016/j.celrep.2020.01.029   
2020 D'Agostino EH, Flynn AR, Cornelison JL, Mays SG, Patel A, Jui NT, Ortlund EA. Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors. Acs Medicinal Chemistry Letters. 11: 365-370. PMID 32184971 DOI: 10.1021/acsmedchemlett.9b00442   
2020 Nguyen T, Lee S, Yang YA, Ahn C, Sim JH, Kei TG, Barnard KN, Yu H, Millano SK, Chen X, Parrish CR, Song J. The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Plos Pathogens. 16: e1008336. PMID 32084237 DOI: 10.1371/journal.ppat.1008336   
2020 Ji B, Liu S, He X, Man VH, Xie XQ, Wang J. Prediction of the binding affinities and selectivity for CB1 and CB2 ligands using homology modeling, molecular docking, molecular dynamics simulations, and MM-PBSA binding free energy calculations. Acs Chemical Neuroscience. PMID 32196303 DOI: 10.1021/acschemneuro.9b00696   
2020 Macleod OJS, Bart JM, MacGregor P, Peacock L, Savill NJ, Hester S, Ravel S, Sunter JD, Trevor C, Rust S, Vaughan TJ, Minter R, Mohammed S, Gibson W, Taylor MC, et al. A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies. Nature Communications. 11: 1326. PMID 32165615 DOI: 10.1038/s41467-020-15125-y   
2020 Kozma MT, Ngo-Vu H, Wong YY, Shukla NS, Pawar SD, Senatore A, Schmidt M, Derby CD. Comparison of transcriptomes from two chemosensory organs in four decapod crustaceans reveals hundreds of candidate chemoreceptor proteins. Plos One. 15: e0230266. PMID 32163507 DOI: 10.1371/journal.pone.0230266   
2020 Randáková A, Nelic D, Doležal V, El-Fakahany EE, Boulos J, Jakubík J. Agonist-Specific Conformations of the M Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics. Journal of Chemical Information and Modeling. PMID 32130001 DOI: 10.1021/acs.jcim.0c00041   
2020 Wang J, Wu M, Wu L, Xu Y, Li F, Wu Y, Popov P, Wang L, Bai F, Zhao S, Liu ZJ, Hua T. The structural study of mutation-induced inactivation of human muscarinic receptor M4. Iucrj. 7: 294-305. PMID 32148857 DOI: 10.1107/S2052252520000597   
2020 Gibson DA, Esnal-Zufiaurre A, Bajo-Santos C, Collins F, Critchley HOD, Saunders PTK. Profiling the expression and function of oestrogen receptor isoform ER46 in human endometrial tissues and uterine natural killer cells. Human Reproduction (Oxford, England). PMID 32108901 DOI: 10.1093/humrep/dez306   
2020 Boursier ME, Levin S, Zimmerman K, Machleidt T, Hurst R, Butler BL, Eggers CT, Kirkland TA, Wood KV, Friedman Ohana R. The luminescent HiBiT peptide enables selective quantitation of GPCR ligand engagement and internalization in living cells. The Journal of Biological Chemistry. PMID 32107310 DOI: 10.1074/jbc.RA119.011952   
2020 Hu B, Joseph J, Geng X, Wu Y, Suleiman MR, Liu X, Shi J, Wang X, He Z, Wang J, Cheng M. Refined pharmacophore features for virtual screening of human thromboxane A2 receptor antagonists. Computational Biology and Chemistry. 86: 107249. PMID 32199335 DOI: 10.1016/j.compbiolchem.2020.107249   
2020 Niedbala P, Majdecki M, Dabrowa K, Jurczak J. Selective carboxylate recognition using urea-functionalized unclosed cryptands - mild synthesis and complexation studies. The Journal of Organic Chemistry. PMID 32142280 DOI: 10.1021/acs.joc.9b03082   
2020 Zhao J, Wang Y, Li X, Gai Z. Genome-wide identification and characterization of Toll-like receptors (TLRs) in housefly (Musca domestica) and their roles in the insecticide resistance. International Journal of Biological Macromolecules. PMID 32045613 DOI: 10.1016/j.ijbiomac.2020.02.061   
2020 Xu X, Yang Z, Zhu K, Li H, Qin Z, Duan H. Computational insight on the binding and selectivity of target-subunit-dependent for neonicotinoid insecticides. Journal of Molecular Graphics & Modelling. 98: 107586. PMID 32200280 DOI: 10.1016/j.jmgm.2020.107586   
2020 Kayser S, Hansen JC, Staudt M, Moroz A, Larsen Y, Temperini P, Yi F, Syrenne JT, Krogsgaard-Larsen N, Iliadis S, Nielsen B, Hansen KB, Pickering DS, Bunch L. Stereoselective Synthesis of New (2,3)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors. Acs Chemical Neuroscience. PMID 32065744 DOI: 10.1021/acschemneuro.0c00003   
2020 Torres-Vergara P, Ho YS, Espinoza F, Nualart F, Escudero C, Penny J. The Constitutive Androstane Receptor and Pregnane X Receptor in the brain. British Journal of Pharmacology. PMID 32201941 DOI: 10.1111/bph.15055   
2020 Wang J, Song X, Zhang D, Chen X, Li X, Sun Y, Li C, Song Y, Ding Y, Ren R, Harrington EH, Hu LA, Zhong W, Xu C, Huang X, et al. Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Research. PMID 32047270 DOI: 10.1038/s41422-020-0280-2   
2020 Nair S, Trummell HQ, Rajbhandari R, Thudi NK, Nozell SE, Warram JM, Willey CD, Yang ES, Placzek WJ, Bonner JA, Bredel M. Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer. Plos One. 15: e0229077. PMID 32069320 DOI: 10.1371/journal.pone.0229077   
2020 Gray RA, Whalley BJ. The proposed mechanisms of action of CBD in epilepsy. Epileptic Disorders : International Epilepsy Journal With Videotape. 22: 10-15. PMID 32053110 DOI: 10.1684/epd.2020.1135   
2020 Li J, Liu H, Zuo R, Yang J, Li N. Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin αβ. Chemosphere. 249: 126034. PMID 32062553 DOI: 10.1016/j.chemosphere.2020.126034   
2020 Habib H, Haider MR, Sharma S, Masroor Ali Beg M, Ahmad S, Dabeer S, Yar MS, Raisuddin S. Molecular interactions of vinclozolin metabolites with human estrogen receptors 1GWR-α and 1QKM and androgen receptor 2AM9-β: Implication for endocrine disruption. Toxicology Mechanisms and Methods. 1-37. PMID 32208804 DOI: 10.1080/15376516.2020.1747123   
2020 Mayasich SA, Clarke BL. Vasotocin and the origins of the vasopressin/oxytocin receptor gene family. Vitamins and Hormones. 113: 1-27. PMID 32138945 DOI: 10.1016/bs.vh.2019.08.018   
2020 Keifer O, Kambara K, Lau A, Makinson S, Bertrand D. Chemogenetics a Robust Approach to Pharmacology and Gene Therapy. Biochemical Pharmacology. 113889. PMID 32119836 DOI: 10.1016/j.bcp.2020.113889   
2020 Serra-Mestres J, Villagrasa-Blasco B, Thacker V, Jaimes-Albornoz W, Sharma P, Isetta M. Catatonia in N-methyl-d-aspartate receptor antibody encephalitis: Phenomenological characteristics from a systematic review of case reports. General Hospital Psychiatry. 64: 9-16. PMID 32070914 DOI: 10.1016/j.genhosppsych.2020.01.002