Jordi Serrats - Related publications

Takeda California 
Drug Discovery
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Wang JW, Gao F, Wang ZL, Wang XC, Yang J, Ma BR, Wang HS, Xie W, Guo Y, Zhang L. Activation and blockade of dorsal hippocampal serotonin4 receptors produce antidepressant effects in the hemiparkinsonian rats. Brain Research. 147426. PMID 33737063 DOI: 10.1016/j.brainres.2021.147426   
2021 Saeed R, Mahmood K, Ali SB, Haleem DJ. Prevention of diet restriction induced hyperactivity but not body-weight reduction in rats co-treated with tryptophan: relationship with striatal serotonin and dopamine metabolism and serotonin-1A auto-receptor expression. Nutritional Neuroscience. 1-10. PMID 33722185 DOI: 10.1080/1028415X.2021.1901046   
2021 Leon RM, Borner T, Stein LM, Urrutia NA, De Jonghe BC, Schmidt HD, Hayes MR. Activation of PPG neurons following acute stressors differentially involves hindbrain serotonin in male rats. Neuropharmacology. 187: 108477. PMID 33581143 DOI: 10.1016/j.neuropharm.2021.108477   
2021 Vilela-Costa HH, Maraschin JC, Casarotto PC, Sant'Ana AB, de Bortoli VC, Vicente MA, de Campos AC, Guimarães FS, Zangrossi H. ROLE OF 5-HT AND 5-HT RECEPTORS OF THE DORSAL PERIAQUEDUCTAL GRAY IN THE ANXIETY- AND PANIC-MODULATING EFFECTS OF ANTIDEPRESSANTS IN RATS. Behavioural Brain Research. 113159. PMID 33571572 DOI: 10.1016/j.bbr.2021.113159   
2021 Galligan JJ. Colonic 5-HT receptors are targets for novel prokinetic drugs. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 33: e14125. PMID 33749067 DOI: 10.1111/nmo.14125   
2021 Eom S, Jung W, Lee J, Yeom HD, Lee S, Kim C, Park HD, Lee JH. Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine. Molecules (Basel, Switzerland). 26. PMID 33668306 DOI: 10.3390/molecules26051211   
2021 Vieira ÉLM, da Silva MCM, Gonçalves AP, Martins GL, Teixeira AL, de Oliveira ACP, Reis HJ. Serotonin and dopamine receptors profile on peripheral immune cells from patients with temporal lobe epilepsy. Journal of Neuroimmunology. 354: 577534. PMID 33713941 DOI: 10.1016/j.jneuroim.2021.577534   
2021 Borroto-Escuela DO, Ambrogini P, Chruścicka B, Lindskog M, Crespo-Ramirez M, Hernández-Mondragón JC, Perez de la Mora M, Schellekens H, Fuxe K. The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects. International Journal of Molecular Sciences. 22. PMID 33672070 DOI: 10.3390/ijms22041927   
2021 Bombardi C, Grandis A, Pivac N, Sagud M, Lucas G, Chagraoui A, Lemaire-Mayo V, De Deurwaerdère P, Di Giovanni G. Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics. Progress in Brain Research. 261: 83-158. PMID 33785139 DOI: 10.1016/bs.pbr.2021.01.031   
2021 Benhadda A, Quentin E, Moutkine I, Chanrion B, Russeau M, Marin P, Levi S, Maroteaux L. Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses. Acs Chemical Neuroscience. PMID 33739808 DOI: 10.1021/acschemneuro.0c00638   
2021 Wang Z, Li C, Ding J, Li Y, Zhou Z, Huang Y, Wang X, Fan H, Huang J, He Y, Li J, Chen J, Qiu P. Basolateral Amygdala Serotonin 2C Receptor Regulates Emotional Disorder-Related Symptoms Induced by Chronic Methamphetamine Administration. Frontiers in Pharmacology. 12: 627307. PMID 33628192 DOI: 10.3389/fphar.2021.627307   
2021 Park S, Kim Y, Lee J, Lee JY, Kim H, Lee S, Oh CM. A Systems Biology Approach to Investigating the Interaction between Serotonin Synthesis by Tryptophan Hydroxylase and the Metabolic Homeostasis. International Journal of Molecular Sciences. 22. PMID 33671067 DOI: 10.3390/ijms22052452   
2021 de Filippo R, Rost BR, Stumpf A, Cooper C, Tukker JJ, Harms C, Beed P, Schmitz D. Somatostatin interneurons activated by 5-HT receptor suppress slow oscillations in medial entorhinal cortex. Elife. 10. PMID 33789079 DOI: 10.7554/eLife.66960   
2021 Zhang B, Yang JW, Han T, Huang DX, Zhao ZH, Feng JQ, Zhou NM, Xie HQ, Wang TM. Identification and characterization of a novel 5-hydroxytryptamine receptor in the sea cucumber Apostichopus japonicus (Selenka). Journal of Experimental Zoology. Part a, Ecological and Integrative Physiology. PMID 33651924 DOI: 10.1002/jez.2450   
2021 Paul N, Raymond J, Lumbreras S, Bartsch D, Weber T, Lau T. Activation of the glucocorticoid receptor rapidly triggers calcium-dependent serotonin release in vitro. Cns Neuroscience & Therapeutics. PMID 33715314 DOI: 10.1111/cns.13634   
2021 Kaczor AA, Targowska-Duda KM, Stępnicki P, Silva AG, Koszła O, Kędzierska E, Grudzińska A, Kruk-Słomka M, Biała G, Castro M. N-(3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propyl)-1H-indazole-3-carboxamide (D2AAK3) as a potential antipsychotic: in vitro, in silico and in vivo evaluation of a multi-target ligand. Neurochemistry International. 105016. PMID 33722679 DOI: 10.1016/j.neuint.2021.105016   
2021 De Deurwaerdere P, Di Giovanni G. 5-HT interaction with other neurotransmitters: An overview. Progress in Brain Research. 259: 1-5. PMID 33541674 DOI: 10.1016/bs.pbr.2021.01.001   
2021 Shen L, Qiu HB, Xu HH, Wei K, Zhao L, Zhu CC, Li CJ, Lu ZJ. Nicotine Withdrawal induces Hyperalgesia via Downregulation of Descending Serotonergic Pathway in the Nucleus Raphe Magnus. Neuropharmacology. 108515. PMID 33722649 DOI: 10.1016/j.neuropharm.2021.108515   
2021 Gao L, Hao C, Chen J, Ma R, Zheng L, Wu Q, Liu X, Liu BF, Zhang G, Chen Y, Jin J. Discovery of a new class of multi-target heterocycle piperidine derivatives as potential antipsychotics with pro-cognitive effect. Bioorganic & Medicinal Chemistry Letters. 127909. PMID 33705900 DOI: 10.1016/j.bmcl.2021.127909   
2021 Dai YQ, Yan XX, Lin YC, Chen HY, Liu XR. Transient Receptor Potential Melastatin 2 Enhances Vascular Reactivity During Development of Atherosclerosis in Mice. American Journal of Hypertension. 34: 121-122. PMID 33599748 DOI: 10.1093/ajh/hpaa154   
2021 Beyeler A, Ju A, Chagraoui A, Cuvelle L, Teixeira M, Di Giovanni G, De Deurwaerdère P. Multiple facets of serotonergic modulation. Progress in Brain Research. 261: 3-39. PMID 33785133 DOI: 10.1016/bs.pbr.2021.02.002   
2021 Colangeli R, Teskey GC, Di Giovanni G. Endocannabinoid-serotonin systems interaction in health and disease. Progress in Brain Research. 259: 83-134. PMID 33541682 DOI: 10.1016/bs.pbr.2021.01.003   
2021 Cummings KJ. Eupnea and gasping in vivo are facilitated by the activation of 5-HT receptors. Journal of Neurophysiology. PMID 33760672 DOI: 10.1152/jn.00088.2021   
2021 Song JL, Zheng SY, He RL, Gui LX, Lin MJ, Sham JSK. Serotonin and chronic hypoxic pulmonary hypertension activate a NADPH oxidase 4 and TRPM2 dependent pathway for pulmonary arterial smooth muscle cell proliferation and migration. Vascular Pharmacology. 106860. PMID 33794383 DOI: 10.1016/j.vph.2021.106860   
2021 Liu WG, Zhang LM, Yao JQ, Yin YY, Zhang XY, Li YF, Cao JB. Anti-PTSD Effects of Hypidone Hydrochloride (YL-0919): A Novel Combined Selective 5-HT Reuptake Inhibitor/5-HT Receptor Partial Agonist/5-HT Receptor Full Agonist. Frontiers in Pharmacology. 12: 625547. PMID 33643051 DOI: 10.3389/fphar.2021.625547   
2021 Schrankl J, Fuchs M, Broeker K, Daniel C, Kurtz A, Wagner C. Localization of Angiotensin II Type 1 receptor gene expression in rodent and human kidneys. American Journal of Physiology. Renal Physiology. PMID 33615887 DOI: 10.1152/ajprenal.00550.2020   
2021 Wan J, Peng W, Li X, Qian T, Song K, Zeng J, Deng F, Hao S, Feng J, Zhang P, Zhang Y, Zou J, Pan S, Shin M, Venton BJ, et al. A genetically encoded sensor for measuring serotonin dynamics. Nature Neuroscience. PMID 33821000 DOI: 10.1038/s41593-021-00823-7   
2021 Król M, Ślifirski G, Kleps J, Ulenberg S, Belka M, Bączek T, Siwek A, Stachowicz K, Szewczyk B, Nowak G, Duszyńska B, Herold F. Synthesis of Novel Pyrido[1,2-]pyrimidine Derivatives with 6-Fluoro-3-(4-piperidynyl)-1,2-benzisoxazole Moiety as Potential SSRI and 5-HT Receptor Ligands. International Journal of Molecular Sciences. 22. PMID 33652672 DOI: 10.3390/ijms22052329   
2021 Sun X, Zu Y, Li X, Zhao S, Sun X, Li L, Zhang X, Wang W, Liang Y, Wang W, Liang X, Gao M, Sun C, Guan X, Tang M. Corticosterone-induced Hippocampal 5-HT Responses were Muted in Depressive-like State. Acs Chemical Neuroscience. PMID 33586968 DOI: 10.1021/acschemneuro.0c00334   
2021 Ofori E, Onyameh EK, Gonela UM, Voshavar C, Bricker B, Swanson TL, Eshleman AJ, Schmachtenberg JL, Bloom SH, Janowsky AJ, Ablordeppey SY. New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. European Journal of Medicinal Chemistry. 214: 113243. PMID 33582388 DOI: 10.1016/j.ejmech.2021.113243   
2021 Ostrowska K, Leśniak A, Czarnocka Z, Chmiel J, Bujalska-Zadrożny M, Trzaskowski B. Design, Synthesis, and Biological Evaluation of a Series of 5- and 7-Hydroxycoumarin Derivatives as 5-HT Serotonin Receptor Antagonists. Pharmaceuticals (Basel, Switzerland). 14. PMID 33668396 DOI: 10.3390/ph14030179   
2021 Zuena AR, Casolini P, Venerosi A, Alemà GS, Nicoletti F, Calamandrei G. Selective reduction in the expression of type-1 metabotropic glutamate receptors in the hippocampus of adult rats born by caesarean section. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 33759234 DOI: 10.1002/jdn.10105   
2021 Yang WS, Shi ZG, Dong XZ, Liu P, Chen ML, Hu Y. Involvement of 5-HT-BDNF signaling axis in mediating synergistic antidepressant-like effects after combined administration of two oligosaccharide esters. Food Science & Nutrition. 9: 1180-1191. PMID 33598202 DOI: 10.1002/fsn3.2098   
2021 Hopper AT, Juhl M, Hornberg J, Badolo L, Kilburn JP, Thougaard A, Smagin G, Song D, Calice L, Menon V, Dale E, Zhang H, Cajina M, Nattini ME, Gandhi A, et al. Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139. Journal of Medicinal Chemistry. PMID 33822617 DOI: 10.1021/acs.jmedchem.0c02249   
2021 Kawano Y, Katsuyama M, Nagata M, Obana M, Nakamatsu S, Mori A, Sakamoto N, Mano Y, Negishi K, Shimada S, Aoyama T. Antiplatelet Effect of Mirtazapine via Co-blocking of the 5-HT and α-Adrenergic Receptors on Platelets. Biological & Pharmaceutical Bulletin. 44: 238-244. PMID 33518675 DOI: 10.1248/bpb.b20-00698   
2021 Kumar A, Sarkar P, Chattopadhyay A. Metabolic Depletion of Sphingolipids Reduces Cell Surface Population of the Human Serotonin Receptor due to Impaired Trafficking. Acs Chemical Neuroscience. PMID 33760584 DOI: 10.1021/acschemneuro.1c00017   
2021 Shao C, Shen L, Qiu C, Wang Y, Qian Y, Chen J, Ouyang Z, Zhang P, Guan X, Xie J, Liu G, Peng C. Characterizing the impact of high temperature during the grain filling on phytohormone levels, enzyme activities and metabolic profiles of the early indica-rice variety. Plant Biology (Stuttgart, Germany). PMID 33721388 DOI: 10.1111/plb.13253   
2021 Yu Y, Chen W, Meng D, Zhou XM, Wang LL, Xu C. A Cannabinoid-1 Receptor Antagonist MJ08 with Different Effects in Stomach and Small Intestine. Assay and Drug Development Technologies. PMID 33784479 DOI: 10.1089/adt.2020.1041   
2021 Campagno KE, Mitchell CH. The P2X Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis. Frontiers in Cellular Neuroscience. 15: 645244. PMID 33790743 DOI: 10.3389/fncel.2021.645244   
2021 Park MTM, Jeon P, Khan AR, Dempster K, Chakravarty MM, Lerch JP, Mackinley M, Théberge J, Palaniyappan L. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110297. PMID 33691200 DOI: 10.1016/j.pnpbp.2021.110297   
2021 Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, et al. Structural insights into the lipid and ligand regulation of serotonin receptors. Nature. PMID 33762731 DOI: 10.1038/s41586-021-03376-8   
2021 Ko IG, Jin JJ, Hwang L, Kim SH, Kim CJ, Jeon JW, Chung JY, Han JH. Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway. Plos One. 16: e0248689. PMID 33735236 DOI: 10.1371/journal.pone.0248689   
2021 Pourhamzeh M, Moravej FG, Arabi M, Shahriari E, Mehrabi S, Ward R, Ahadi R, Joghataei MT. The Roles of Serotonin in Neuropsychiatric Disorders. Cellular and Molecular Neurobiology. PMID 33651238 DOI: 10.1007/s10571-021-01064-9   
2021 Böhm M, Gellner R. [Neuroendorine paraneoplastic syndromes]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete. PMID 33661337 DOI: 10.1007/s00105-021-04778-5   
2021 Vieta E, Sachs G, Chang D, Hellsten J, Brewer C, Peters-Strickland T, Hefting N. Two randomized, double-blind, placebo-controlled trials and one open-label, long-term trial of brexpiprazole for the acute treatment of bipolar mania. Journal of Psychopharmacology (Oxford, England). 269881120985102. PMID 33691517 DOI: 10.1177/0269881120985102   
2021 Zhang S, Li X, Zhao S, Drobizhev M, Ai HW. A fast, high-affinity fluorescent serotonin biosensor engineered from a tick lipocalin. Nature Methods. 18: 258-261. PMID 33633410 DOI: 10.1038/s41592-021-01078-7   
2021 Okada M, Matsumoto R, Yamamoto Y, Fukuyama K. Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. International Journal of Molecular Sciences. 22. PMID 33572981 DOI: 10.3390/ijms22031351   
2021 Song S, Kong X, Borlongan C, Sava V, Sanchez-Ramos J. Granulocyte Colony-Stimulating Factor Enhances Brain Repair Following Traumatic Brain Injury Without Requiring Activation of Cannabinoid Receptors. Cannabis and Cannabinoid Research. 6: 48-57. PMID 33614952 DOI: 10.1089/can.2019.0090   
2021 Cantero-Navarro E, Fernández-Fernández B, Ramos AM, Rayego-Mateos S, Rodrigues-Diez RR, Sánchez-Niño MD, Sanz AB, Ruiz-Ortega M, Ortiz A. Renin-angiotensin system and inflammation update. Molecular and Cellular Endocrinology. 111254. PMID 33798633 DOI: 10.1016/j.mce.2021.111254   
2021 Yang NN, Yang JW, Ye Y, Huang J, Wang L, Wang Y, Su XT, Lin Y, Yu FT, Ma SM, Qi LY, Lin LL, Wang LQ, Shi GX, Li HP, et al. Electroacupuncture ameliorates intestinal inflammation by activating α7nAChR-mediated JAK2/STAT3 signaling pathway in postoperative ileus. Theranostics. 11: 4078-4089. PMID 33754049 DOI: 10.7150/thno.52574