Year |
Citation |
Score |
2014 |
Gosse JA, Taylor VF, Jackson BP, Hamilton JW, Bodwell JE. Monomethylated trivalent arsenic species disrupt steroid receptor interactions with their DNA response elements at non-cytotoxic cellular concentrations. Journal of Applied Toxicology : Jat. 34: 498-505. PMID 23765520 DOI: 10.1002/Jat.2898 |
0.726 |
|
2013 |
Jebbett NJ, Hamilton JW, Rand MD, Eckenstein F. Low level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells. Neurotoxicology. 38: 91-100. PMID 23845766 DOI: 10.1016/J.Neuro.2013.06.008 |
0.361 |
|
2012 |
Wolf B, Schwarzer A, Côté AL, Hampton TH, Schwaab T, Huarte E, Tomlinson CR, Gui J, Fisher JL, Fadul CE, Hamilton JW, Ernstoff MS. Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine. Plos One. 7: e50221. PMID 23226513 DOI: 10.1371/Journal.Pone.0050221 |
0.35 |
|
2012 |
Kozul-Horvath CD, Zandbergen F, Jackson BP, Enelow RI, Hamilton JW. Effects of low-dose drinking water arsenic on mouse fetal and postnatal growth and development. Plos One. 7: e38249. PMID 22693606 DOI: 10.1371/Journal.Pone.0038249 |
0.308 |
|
2010 |
Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898 |
0.676 |
|
2009 |
Kozul CD, Ely KH, Enelow RI, Hamilton JW. Low-dose arsenic compromises the immune response to influenza A infection in vivo. Environmental Health Perspectives. 117: 1441-7. PMID 19750111 DOI: 10.1289/Ehp.0900911 |
0.311 |
|
2009 |
Barr FD, Krohmer LJ, Hamilton JW, Sheldon LA. Disruption of histone modification and CARM1 recruitment by arsenic represses transcription at glucocorticoid receptor-regulated promoters. Plos One. 4: e6766. PMID 19707557 DOI: 10.1371/Journal.Pone.0006766 |
0.387 |
|
2009 |
Kozul CD, Hampton TH, Davey JC, Gosse JA, Nomikos AP, Eisenhauer PL, Weiss DJ, Thorpe JE, Ihnat MA, Hamilton JW. Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environmental Health Perspectives. 117: 1108-15. PMID 19654921 DOI: 10.1289/Ehp.0800199 |
0.707 |
|
2008 |
Hays AM, Lantz RC, Rodgers LS, Sollome JJ, Vaillancourt RR, Andrew AS, Hamilton JW, Camenisch TD. Arsenic-induced decreases in the vascular matrix. Toxicologic Pathology. 36: 805-17. PMID 18812580 DOI: 10.1177/0192623308323919 |
0.366 |
|
2008 |
Ye S, MacEachran DP, Hamilton JW, O'Toole GA, Stanton BA. Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif. American Journal of Physiology. Cell Physiology. 295: C807-18. PMID 18650266 DOI: 10.1152/Ajpcell.00234.2008 |
0.306 |
|
2008 |
Kozul CD, Nomikos AP, Hampton TH, Warnke LA, Gosse JA, Davey JC, Thorpe JE, Jackson BP, Ihnat MA, Hamilton JW. Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung. Chemico-Biological Interactions. 173: 129-40. PMID 18396267 DOI: 10.1016/J.Cbi.2008.02.008 |
0.688 |
|
2008 |
Davey JC, Nomikos AP, Wungjiranirun M, Sherman JR, Ingram L, Batki C, Lariviere JP, Hamilton JW. Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis. Environmental Health Perspectives. 116: 165-72. PMID 18288313 DOI: 10.1289/Ehp.10131 |
0.42 |
|
2008 |
Gosse JA, Hampton TH, Davey JC, Hamilton JW. A New Approach to Analysis and Interpretation of Toxicogenomic Gene Expression Data and its Importance in Examining Biological Responses to Low, Environmentally Relevant Doses of Toxicants Toxicogenomics: a Powerful Tool For Toxicity Assessment. 27-57. DOI: 10.1002/9780470699638.ch2 |
0.67 |
|
2007 |
Shaw JR, Colbourne JK, Davey JC, Glaholt SP, Hampton TH, Chen CY, Folt CL, Hamilton JW. Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins. Bmc Genomics. 8: 477. PMID 18154678 DOI: 10.1186/1471-2164-8-477 |
0.358 |
|
2007 |
Shaw JR, Jackson B, Gabor K, Stanton S, Hamilton JW, Stanton BA. The influence of exposure history on arsenic accumulation and toxicity in the killifish, Fundulus heteroclitus. Environmental Toxicology and Chemistry / Setac. 26: 2704-9. PMID 18020683 DOI: 10.1897/07-032.1 |
0.343 |
|
2007 |
Andrew AS, Bernardo V, Warnke LA, Davey JC, Hampton T, Mason RA, Thorpe JE, Ihnat MA, Hamilton JW. Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 75-87. PMID 17682005 DOI: 10.1093/Toxsci/Kfm200 |
0.398 |
|
2007 |
Mustra DJ, Warren AJ, Wilcox DE, Hamilton JW. Preferential binding of human XPA to the mitomycin C-DNA interstrand crosslink and modulation by arsenic and cadmium. Chemico-Biological Interactions. 168: 159-68. PMID 17512921 DOI: 10.1016/J.Cbi.2007.04.004 |
0.345 |
|
2007 |
Miller DS, Shaw JR, Stanton CR, Barnaby R, Karlson KH, Hamilton JW, Stanton BA. MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus). Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 103-10. PMID 17324950 DOI: 10.1093/Toxsci/Kfm030 |
0.343 |
|
2007 |
Davey JC, Bodwell JE, Gosse JA, Hamilton JW. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 75-86. PMID 17283378 DOI: 10.1093/Toxsci/Kfm013 |
0.723 |
|
2007 |
Shaw JR, Gabor K, Hand E, Lankowski A, Durant L, Thibodeau R, Stanton CR, Barnaby R, Coutermarsh B, Karlson KH, Sato JD, Hamilton JW, Stanton BA. Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R1052-60. PMID 17038445 DOI: 10.1152/Ajpregu.00328.2006 |
0.444 |
|
2006 |
Bodwell JE, Gosse JA, Nomikos AP, Hamilton JW. Arsenic disruption of steroid receptor gene activation: Complex dose-response effects are shared by several steroid receptors. Chemical Research in Toxicology. 19: 1619-29. PMID 17173375 DOI: 10.1021/Tx060122Q |
0.717 |
|
2006 |
Andrew AS, Burgess JL, Meza MM, Demidenko E, Waugh MG, Hamilton JW, Karagas MR. Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environmental Health Perspectives. 114: 1193-8. PMID 16882524 DOI: 10.1289/Ehp.9008 |
0.404 |
|
2006 |
Stanton CR, Thibodeau R, Lankowski A, Shaw JR, Hamilton JW, Stanton BA. Arsenic inhibits CFTR-mediated chloride secretion by killifish (Fundulus heteroclitus) opercular membrane. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 17: 269-78. PMID 16791002 DOI: 10.1159/000094139 |
0.332 |
|
2005 |
Maitra R, Hamilton JW. Arsenite regulates Cystic Fibrosis Transmembrane Conductance Regulator and P-glycoprotein: evidence of pathway independence. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 16: 109-18. PMID 16121039 DOI: 10.1159/000087737 |
0.378 |
|
2005 |
Kamat CD, Green DE, Curilla S, Warnke L, Hamilton JW, Sturup S, Clark C, Ihnat MA. Role of HIF signaling on tumorigenesis in response to chronic low-dose arsenic administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 248-57. PMID 15888669 DOI: 10.1093/Toxsci/Kfi190 |
0.301 |
|
2004 |
Bodwell JE, Kingsley LA, Hamilton JW. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chemical Research in Toxicology. 17: 1064-76. PMID 15310238 DOI: 10.1021/Tx0499113 |
0.437 |
|
2003 |
Andrew AS, Warren AJ, Barchowsky A, Temple KA, Klei L, Soucy NV, O'Hara KA, Hamilton JW. Genomic and proteomic profiling of responses to toxic metals in human lung cells. Environmental Health Perspectives. 111: 825-35. PMID 12760830 DOI: 10.1289/Ehp.111-1241504 |
0.375 |
|
2003 |
Andrew AS, Karagas MR, Hamilton JW. Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. International Journal of Cancer. Journal International Du Cancer. 104: 263-8. PMID 12569548 DOI: 10.1002/Ijc.10968 |
0.424 |
|
2003 |
Zheng H, Wang X, Warren AJ, Legerski RJ, Nairn RS, Hamilton JW, Li L. Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Molecular and Cellular Biology. 23: 754-61. PMID 12509472 DOI: 10.1128/Mcb.23.2.754-761.2003 |
0.337 |
|
2001 |
Mustra DJ, Warren AJ, Hamilton JW. Preferential binding of human full-length XPA and the minimal DNA binding domain (XPA-MF122) with the mitomycin C-DNA interstrand cross-link. Biochemistry. 40: 7158-64. PMID 11401562 DOI: 10.1021/Bi002820U |
0.341 |
|
2001 |
Kaltreider RC, Davis AM, Lariviere JP, Hamilton JW. Arsenic alters the function of the glucocorticoid receptor as a transcription factor. Environmental Health Perspectives. 109: 245-51. PMID 11333185 DOI: 10.1289/Ehp.01109245 |
0.462 |
|
2001 |
Maitra R, Halpin PA, Karlson KH, Page RL, Paik DY, Leavitt MO, Moyer BD, Stanton BA, Hamilton JW. Differential effects of mitomycin C and doxorubicin on P-glycoprotein expression Biochemical Journal. 355: 617-624. PMID 11311122 DOI: 10.1042/Bj3550617 |
0.395 |
|
2001 |
Maitra R, Shaw CM, Stanton BA, Hamilton JW. Increased functional cell surface expression of CFTR and DeltaF508-CFTR by the anthracycline doxorubicin. American Journal of Physiology. Cell Physiology. 280: C1031-7. PMID 11287314 DOI: 10.1152/Ajpcell.2001.280.5.C1031 |
0.302 |
|
2001 |
Maitra R, Shaw CM, Stanton BA, Hamilton JW. Functional enhancement of CFTR expression by mitomycin C. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 11: 93-8. PMID 11275687 DOI: 10.1159/000047796 |
0.327 |
|
1999 |
Kaltreider RC, Pesce CA, Ihnat MA, Lariviere JP, Hamilton JW. Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding. Molecular Carcinogenesis. 25: 219-29. PMID 10411148 DOI: 10.1002/(Sici)1098-2744(199907)25:3<219::Aid-Mc8>3.0.Co;2-X |
0.405 |
|
1999 |
Raha A, Hamilton JW, Bresnick E. The existence of the 4S polycyclic aromatic hydrocarbon-protein binding in 14-day-old chick embryo liver. Toxicology and Applied Pharmacology. 158: 1-8. PMID 10387926 DOI: 10.1006/Taap.1999.8671 |
0.329 |
|
1999 |
Yuann JM, Liu KJ, Hamilton JW, Wetterhahn KE. In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI). Carcinogenesis. 20: 1267-75. PMID 10383900 DOI: 10.1093/Carcin/20.7.1267 |
0.641 |
|
1998 |
Caron RM, Hamilton JW. Developmentally specific effects of the DNA cross-linking agent mitomycin C on phosphoenolpyruvate carboxykinase gene expression in vivo: correlation with changes in chromatin structure within the promoter region of the gene. Journal of Biochemical and Molecular Toxicology. 12: 325-37. PMID 9736481 DOI: 10.1002/(Sici)1099-0461(1998)12:6<325::Aid-Jbt2>3.0.Co;2-2 |
0.45 |
|
1998 |
Bentivegna CS, Ihnat MA, Baptiste NS, Hamilton JW. Developmental regulation of the 3-methylcholanthrene- and dioxin-inducible CYP1A5 gene in chick embryo liver in vivo. Toxicology and Applied Pharmacology. 151: 166-73. PMID 9705900 DOI: 10.1006/Taap.1998.8439 |
0.455 |
|
1998 |
Hamilton JW, Kaltreider RC, Bajenova OV, Ihnat MA, McCaffrey J, Turpie BW, Rowell EE, Oh J, Nemeth MJ, Pesce CA, Lariviere JP. Molecular basis for effects of carcinogenic heavy metals on inducible gene expression. Environmental Health Perspectives. 106: 1005-15. PMID 9703486 DOI: 10.1289/Ehp.98106S41005 |
0.442 |
|
1998 |
Warren AJ, Ihnat MA, Ogdon SE, Rowell EE, Hamilton JW. Binding of nuclear proteins associated with mammalian DNA repair to the mitomycin C-DNA interstrand crosslink. Environmental and Molecular Mutagenesis. 31: 70-81. PMID 9464318 DOI: 10.1002/(Sici)1098-2280(1998)31:1<70::Aid-Em10>3.0.Co;2-M |
0.323 |
|
1995 |
Caron RM, Hamilton JW. Preferential effects of the chemotherapeutic DNA crosslinking agent mitomycin C on inducible gene expression in vivo. Environmental and Molecular Mutagenesis. 25: 4-11. PMID 7875125 DOI: 10.1002/Em.2850250103 |
0.448 |
|
1994 |
Alcedo JA, Misra M, Hamilton JW, Wetterhahn KE. The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metallothionein gene in vivo. Carcinogenesis. 15: 1089-92. PMID 8200074 DOI: 10.1093/Carcin/15.5.1089 |
0.672 |
|
1994 |
McCaffrey J, Hamilton JW. Comparison of effects of direct-acting DNA methylating and ethylating agents on inducible gene expression in vivo. Environmental and Molecular Mutagenesis. 23: 164-70. PMID 8162889 DOI: 10.1002/Em.2850230303 |
0.459 |
|
1994 |
McCaffrey J, Hamilton JW. Development regulation of basal and hormone-inducible phosphoenolpyruvate carboxykinase gene expression in chick embryo liver in vivo. Archives of Biochemistry and Biophysics. 309: 10-7. PMID 8117098 DOI: 10.1006/Abbi.1994.1076 |
0.431 |
|
1994 |
Hamilton JW, McCaffrey J, Caron RM, Louis CA, Treadwell MD, Hunt SR, Reed MJ, Doherty KA. Genotoxic chemical carcinogens target inducible genes in vivo. Annals of the New York Academy of Sciences. 726: 343-5. PMID 8092700 DOI: 10.1111/J.1749-6632.1994.Tb52846.X |
0.326 |
|
1994 |
McCaffrey J, Wolf CM, Hamilton JW. Effects of the genotoxic carcinogen chromium(VI) on basal and hormone-inducible phosphoenolpyruvate carboxykinase gene expression in vivo: correlation with glucocorticoid- and developmentally regulated expression. Molecular Carcinogenesis. 10: 189-98. PMID 8068179 DOI: 10.1002/Mc.2940100403 |
0.471 |
|
1993 |
Hamilton JW, Louis CA, Doherty KA, Hunt SR, Reed MJ, Treadwell MD. Preferential alteration of inducible gene expression in vivo by carcinogens that induce bulky DNA lesions. Molecular Carcinogenesis. 8: 34-43. PMID 7688968 DOI: 10.1002/Mc.2940080109 |
0.473 |
|
1992 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes. Archives of Biochemistry and Biophysics. 298: 96-104. PMID 1524447 DOI: 10.1016/0003-9861(92)90099-I |
0.69 |
|
1991 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Archives of Biochemistry and Biophysics. 289: 387-92. PMID 1898078 DOI: 10.1016/0003-9861(91)90428-L |
0.671 |
|
1991 |
Mackie JE, Back DW, Hamilton JW, Marks GS. Elevation of delta-aminolevulinic acid synthase and cytochrome PB1 P450 messenger RNA levels by dihydropyridines, dihydroquinolines, sydnones, and N-ethylprotoporphyrin IX. Biochemical Pharmacology. 42: 475-83. PMID 1859461 DOI: 10.1016/0006-2952(91)90308-R |
0.338 |
|
1989 |
Qureshi MA, Bloom SE, Hamilton JW, Dietert RR. Toxic effects of methyl methanesulfonate (MMS) on activated macrophages from chickens. Environmental and Molecular Mutagenesis. 13: 253-62. PMID 2707255 DOI: 10.1002/Em.2850130309 |
0.549 |
|
1989 |
Hamilton JW, Wetterhahn KE. Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium(VI)-induced DNA damage Molecular Carcinogenesis. 2: 274-286. PMID 2604865 DOI: 10.1002/Mc.2940020508 |
0.707 |
|
1989 |
Denison MS, Hamilton JW, Young CM, Wilkinson CF. Nickel and nickel-conjugate metabolism and acute toxicity. Veterinary and Human Toxicology. 31: 498-9. PMID 2603369 |
0.464 |
|
1989 |
Wetterhahn KE, Hamilton JW. Molecular basis of hexavalent chromium carcinogenicity: effect on gene expression. The Science of the Total Environment. 86: 113-29. PMID 2602931 DOI: 10.1016/0048-9697(89)90199-X |
0.7 |
|
1989 |
Wetterhahn KE, Hamilton JW, Aiyar J, Borges KM, Floyd R. Mechanism of chromium(VI) carcinogenesis. Reactive intermediates and effect on gene expression. Biological Trace Element Research. 21: 405-11. PMID 2484620 DOI: 10.1007/Bf02917282 |
0.675 |
|
1988 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Wetterhahn KE. Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem Biochemical Journal. 255: 267-275. PMID 3196319 DOI: 10.1042/Bj2570936 |
0.663 |
|
1986 |
Hamilton JW, Wetterhahn KE. Chromium (vi)-induced dna damage in chick embryo liver and blood cells in vivo Carcinogenesis. 7: 2085-2088. PMID 3779902 DOI: 10.1093/Carcin/7.12.2085 |
0.666 |
|
1986 |
Hamilton JW, Bloom SE. Correlation between induction of xenobiotic metabolism and DNA damage from chemical carcinogens in the chick embryo in vivo. Carcinogenesis. 7: 1101-6. PMID 3087644 DOI: 10.1093/Carcin/7.7.1101 |
0.584 |
|
1986 |
Denison MS, Okey AB, Hamilton JW, Bloom SE, Wilkinson CF. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. Journal of Biochemical Toxicology. 1: 39-49. PMID 2856072 DOI: 10.1002/Jbt.2570010305 |
0.674 |
|
1985 |
Denison MS, Hamilton JW, Wilkinson CF. Comparative studies of aryl hydrocarbon hydroxylase and the Ah receptor in nonmammalian species. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 80: 319-24. PMID 2861016 DOI: 10.1016/0742-8413(85)90063-5 |
0.558 |
|
1985 |
Hamilton JW, Bloom SE. Correlation between mixed-function oxidase enzyme induction and genotoxicity, in vivo Federation Proceedings. 44: No. 533. |
0.476 |
|
1984 |
Hamilton JW, Bloom SE. Correlation between mixed-function oxidase enzyme induction and aflatoxin B1-induced unscheduled DNA synthesis in the chick embryo, in vivo. Environmental Mutagenesis. 6: 41-8. PMID 6420149 DOI: 10.1002/Em.2860060106 |
0.581 |
|
1984 |
Hamilton JW, Denison MS, Bloom SE, Wilkinson CF. Ontogeny of the cytosolic TCDD receptor in the chick embryo and neonate Federation Proceedings. 43: no. 1708. |
0.634 |
|
1983 |
Hamilton JW, Bloom SE. Developmental differences in basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in chick embryo liver and lung in ovo. Biochemical Pharmacology. 32: 2986-8. PMID 6626269 DOI: 10.1016/0006-2952(83)90409-4 |
0.533 |
|
1983 |
Hamilton JW, Denison MS, Bloom SE. Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo. Proceedings of the National Academy of Sciences of the United States of America. 80: 3372-6. PMID 6407011 DOI: 10.1073/Pnas.80.11.3372 |
0.55 |
|
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