Joshua W. Hamilton - Publications

Affiliations: 
2005-2007 Physiology Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
Website:
http://dartmed.dartmouth.edu/spring08/html/faculty_focus.php

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Gosse JA, Taylor VF, Jackson BP, Hamilton JW, Bodwell JE. Monomethylated trivalent arsenic species disrupt steroid receptor interactions with their DNA response elements at non-cytotoxic cellular concentrations. Journal of Applied Toxicology : Jat. 34: 498-505. PMID 23765520 DOI: 10.1002/Jat.2898  0.726
2013 Jebbett NJ, Hamilton JW, Rand MD, Eckenstein F. Low level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells. Neurotoxicology. 38: 91-100. PMID 23845766 DOI: 10.1016/J.Neuro.2013.06.008  0.361
2012 Wolf B, Schwarzer A, Côté AL, Hampton TH, Schwaab T, Huarte E, Tomlinson CR, Gui J, Fisher JL, Fadul CE, Hamilton JW, Ernstoff MS. Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine. Plos One. 7: e50221. PMID 23226513 DOI: 10.1371/Journal.Pone.0050221  0.35
2012 Kozul-Horvath CD, Zandbergen F, Jackson BP, Enelow RI, Hamilton JW. Effects of low-dose drinking water arsenic on mouse fetal and postnatal growth and development. Plos One. 7: e38249. PMID 22693606 DOI: 10.1371/Journal.Pone.0038249  0.308
2010 Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898  0.676
2009 Kozul CD, Ely KH, Enelow RI, Hamilton JW. Low-dose arsenic compromises the immune response to influenza A infection in vivo. Environmental Health Perspectives. 117: 1441-7. PMID 19750111 DOI: 10.1289/Ehp.0900911  0.311
2009 Barr FD, Krohmer LJ, Hamilton JW, Sheldon LA. Disruption of histone modification and CARM1 recruitment by arsenic represses transcription at glucocorticoid receptor-regulated promoters. Plos One. 4: e6766. PMID 19707557 DOI: 10.1371/Journal.Pone.0006766  0.387
2009 Kozul CD, Hampton TH, Davey JC, Gosse JA, Nomikos AP, Eisenhauer PL, Weiss DJ, Thorpe JE, Ihnat MA, Hamilton JW. Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environmental Health Perspectives. 117: 1108-15. PMID 19654921 DOI: 10.1289/Ehp.0800199  0.707
2008 Hays AM, Lantz RC, Rodgers LS, Sollome JJ, Vaillancourt RR, Andrew AS, Hamilton JW, Camenisch TD. Arsenic-induced decreases in the vascular matrix. Toxicologic Pathology. 36: 805-17. PMID 18812580 DOI: 10.1177/0192623308323919  0.366
2008 Ye S, MacEachran DP, Hamilton JW, O'Toole GA, Stanton BA. Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif. American Journal of Physiology. Cell Physiology. 295: C807-18. PMID 18650266 DOI: 10.1152/Ajpcell.00234.2008  0.306
2008 Kozul CD, Nomikos AP, Hampton TH, Warnke LA, Gosse JA, Davey JC, Thorpe JE, Jackson BP, Ihnat MA, Hamilton JW. Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung. Chemico-Biological Interactions. 173: 129-40. PMID 18396267 DOI: 10.1016/J.Cbi.2008.02.008  0.688
2008 Davey JC, Nomikos AP, Wungjiranirun M, Sherman JR, Ingram L, Batki C, Lariviere JP, Hamilton JW. Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis. Environmental Health Perspectives. 116: 165-72. PMID 18288313 DOI: 10.1289/Ehp.10131  0.42
2008 Gosse JA, Hampton TH, Davey JC, Hamilton JW. A New Approach to Analysis and Interpretation of Toxicogenomic Gene Expression Data and its Importance in Examining Biological Responses to Low, Environmentally Relevant Doses of Toxicants Toxicogenomics: a Powerful Tool For Toxicity Assessment. 27-57. DOI: 10.1002/9780470699638.ch2  0.67
2007 Shaw JR, Colbourne JK, Davey JC, Glaholt SP, Hampton TH, Chen CY, Folt CL, Hamilton JW. Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins. Bmc Genomics. 8: 477. PMID 18154678 DOI: 10.1186/1471-2164-8-477  0.358
2007 Shaw JR, Jackson B, Gabor K, Stanton S, Hamilton JW, Stanton BA. The influence of exposure history on arsenic accumulation and toxicity in the killifish, Fundulus heteroclitus. Environmental Toxicology and Chemistry / Setac. 26: 2704-9. PMID 18020683 DOI: 10.1897/07-032.1  0.343
2007 Andrew AS, Bernardo V, Warnke LA, Davey JC, Hampton T, Mason RA, Thorpe JE, Ihnat MA, Hamilton JW. Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 75-87. PMID 17682005 DOI: 10.1093/Toxsci/Kfm200  0.398
2007 Mustra DJ, Warren AJ, Wilcox DE, Hamilton JW. Preferential binding of human XPA to the mitomycin C-DNA interstrand crosslink and modulation by arsenic and cadmium. Chemico-Biological Interactions. 168: 159-68. PMID 17512921 DOI: 10.1016/J.Cbi.2007.04.004  0.345
2007 Miller DS, Shaw JR, Stanton CR, Barnaby R, Karlson KH, Hamilton JW, Stanton BA. MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus). Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 103-10. PMID 17324950 DOI: 10.1093/Toxsci/Kfm030  0.343
2007 Davey JC, Bodwell JE, Gosse JA, Hamilton JW. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 75-86. PMID 17283378 DOI: 10.1093/Toxsci/Kfm013  0.723
2007 Shaw JR, Gabor K, Hand E, Lankowski A, Durant L, Thibodeau R, Stanton CR, Barnaby R, Coutermarsh B, Karlson KH, Sato JD, Hamilton JW, Stanton BA. Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R1052-60. PMID 17038445 DOI: 10.1152/Ajpregu.00328.2006  0.444
2006 Bodwell JE, Gosse JA, Nomikos AP, Hamilton JW. Arsenic disruption of steroid receptor gene activation: Complex dose-response effects are shared by several steroid receptors. Chemical Research in Toxicology. 19: 1619-29. PMID 17173375 DOI: 10.1021/Tx060122Q  0.717
2006 Andrew AS, Burgess JL, Meza MM, Demidenko E, Waugh MG, Hamilton JW, Karagas MR. Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environmental Health Perspectives. 114: 1193-8. PMID 16882524 DOI: 10.1289/Ehp.9008  0.404
2006 Stanton CR, Thibodeau R, Lankowski A, Shaw JR, Hamilton JW, Stanton BA. Arsenic inhibits CFTR-mediated chloride secretion by killifish (Fundulus heteroclitus) opercular membrane. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 17: 269-78. PMID 16791002 DOI: 10.1159/000094139  0.332
2005 Maitra R, Hamilton JW. Arsenite regulates Cystic Fibrosis Transmembrane Conductance Regulator and P-glycoprotein: evidence of pathway independence. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 16: 109-18. PMID 16121039 DOI: 10.1159/000087737  0.378
2005 Kamat CD, Green DE, Curilla S, Warnke L, Hamilton JW, Sturup S, Clark C, Ihnat MA. Role of HIF signaling on tumorigenesis in response to chronic low-dose arsenic administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 248-57. PMID 15888669 DOI: 10.1093/Toxsci/Kfi190  0.301
2004 Bodwell JE, Kingsley LA, Hamilton JW. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chemical Research in Toxicology. 17: 1064-76. PMID 15310238 DOI: 10.1021/Tx0499113  0.437
2003 Andrew AS, Warren AJ, Barchowsky A, Temple KA, Klei L, Soucy NV, O'Hara KA, Hamilton JW. Genomic and proteomic profiling of responses to toxic metals in human lung cells. Environmental Health Perspectives. 111: 825-35. PMID 12760830 DOI: 10.1289/Ehp.111-1241504  0.375
2003 Andrew AS, Karagas MR, Hamilton JW. Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. International Journal of Cancer. Journal International Du Cancer. 104: 263-8. PMID 12569548 DOI: 10.1002/Ijc.10968  0.424
2003 Zheng H, Wang X, Warren AJ, Legerski RJ, Nairn RS, Hamilton JW, Li L. Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Molecular and Cellular Biology. 23: 754-61. PMID 12509472 DOI: 10.1128/Mcb.23.2.754-761.2003  0.337
2001 Mustra DJ, Warren AJ, Hamilton JW. Preferential binding of human full-length XPA and the minimal DNA binding domain (XPA-MF122) with the mitomycin C-DNA interstrand cross-link. Biochemistry. 40: 7158-64. PMID 11401562 DOI: 10.1021/Bi002820U  0.341
2001 Kaltreider RC, Davis AM, Lariviere JP, Hamilton JW. Arsenic alters the function of the glucocorticoid receptor as a transcription factor. Environmental Health Perspectives. 109: 245-51. PMID 11333185 DOI: 10.1289/Ehp.01109245  0.462
2001 Maitra R, Halpin PA, Karlson KH, Page RL, Paik DY, Leavitt MO, Moyer BD, Stanton BA, Hamilton JW. Differential effects of mitomycin C and doxorubicin on P-glycoprotein expression Biochemical Journal. 355: 617-624. PMID 11311122 DOI: 10.1042/Bj3550617  0.395
2001 Maitra R, Shaw CM, Stanton BA, Hamilton JW. Increased functional cell surface expression of CFTR and DeltaF508-CFTR by the anthracycline doxorubicin. American Journal of Physiology. Cell Physiology. 280: C1031-7. PMID 11287314 DOI: 10.1152/Ajpcell.2001.280.5.C1031  0.302
2001 Maitra R, Shaw CM, Stanton BA, Hamilton JW. Functional enhancement of CFTR expression by mitomycin C. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 11: 93-8. PMID 11275687 DOI: 10.1159/000047796  0.327
1999 Kaltreider RC, Pesce CA, Ihnat MA, Lariviere JP, Hamilton JW. Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding. Molecular Carcinogenesis. 25: 219-29. PMID 10411148 DOI: 10.1002/(Sici)1098-2744(199907)25:3<219::Aid-Mc8>3.0.Co;2-X  0.405
1999 Raha A, Hamilton JW, Bresnick E. The existence of the 4S polycyclic aromatic hydrocarbon-protein binding in 14-day-old chick embryo liver. Toxicology and Applied Pharmacology. 158: 1-8. PMID 10387926 DOI: 10.1006/Taap.1999.8671  0.329
1999 Yuann JM, Liu KJ, Hamilton JW, Wetterhahn KE. In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI). Carcinogenesis. 20: 1267-75. PMID 10383900 DOI: 10.1093/Carcin/20.7.1267  0.641
1998 Caron RM, Hamilton JW. Developmentally specific effects of the DNA cross-linking agent mitomycin C on phosphoenolpyruvate carboxykinase gene expression in vivo: correlation with changes in chromatin structure within the promoter region of the gene. Journal of Biochemical and Molecular Toxicology. 12: 325-37. PMID 9736481 DOI: 10.1002/(Sici)1099-0461(1998)12:6<325::Aid-Jbt2>3.0.Co;2-2  0.45
1998 Bentivegna CS, Ihnat MA, Baptiste NS, Hamilton JW. Developmental regulation of the 3-methylcholanthrene- and dioxin-inducible CYP1A5 gene in chick embryo liver in vivo. Toxicology and Applied Pharmacology. 151: 166-73. PMID 9705900 DOI: 10.1006/Taap.1998.8439  0.455
1998 Hamilton JW, Kaltreider RC, Bajenova OV, Ihnat MA, McCaffrey J, Turpie BW, Rowell EE, Oh J, Nemeth MJ, Pesce CA, Lariviere JP. Molecular basis for effects of carcinogenic heavy metals on inducible gene expression. Environmental Health Perspectives. 106: 1005-15. PMID 9703486 DOI: 10.1289/Ehp.98106S41005  0.442
1998 Warren AJ, Ihnat MA, Ogdon SE, Rowell EE, Hamilton JW. Binding of nuclear proteins associated with mammalian DNA repair to the mitomycin C-DNA interstrand crosslink. Environmental and Molecular Mutagenesis. 31: 70-81. PMID 9464318 DOI: 10.1002/(Sici)1098-2280(1998)31:1<70::Aid-Em10>3.0.Co;2-M  0.323
1995 Caron RM, Hamilton JW. Preferential effects of the chemotherapeutic DNA crosslinking agent mitomycin C on inducible gene expression in vivo. Environmental and Molecular Mutagenesis. 25: 4-11. PMID 7875125 DOI: 10.1002/Em.2850250103  0.448
1994 Alcedo JA, Misra M, Hamilton JW, Wetterhahn KE. The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metallothionein gene in vivo. Carcinogenesis. 15: 1089-92. PMID 8200074 DOI: 10.1093/Carcin/15.5.1089  0.672
1994 McCaffrey J, Hamilton JW. Comparison of effects of direct-acting DNA methylating and ethylating agents on inducible gene expression in vivo. Environmental and Molecular Mutagenesis. 23: 164-70. PMID 8162889 DOI: 10.1002/Em.2850230303  0.459
1994 McCaffrey J, Hamilton JW. Development regulation of basal and hormone-inducible phosphoenolpyruvate carboxykinase gene expression in chick embryo liver in vivo. Archives of Biochemistry and Biophysics. 309: 10-7. PMID 8117098 DOI: 10.1006/Abbi.1994.1076  0.431
1994 Hamilton JW, McCaffrey J, Caron RM, Louis CA, Treadwell MD, Hunt SR, Reed MJ, Doherty KA. Genotoxic chemical carcinogens target inducible genes in vivo. Annals of the New York Academy of Sciences. 726: 343-5. PMID 8092700 DOI: 10.1111/J.1749-6632.1994.Tb52846.X  0.326
1994 McCaffrey J, Wolf CM, Hamilton JW. Effects of the genotoxic carcinogen chromium(VI) on basal and hormone-inducible phosphoenolpyruvate carboxykinase gene expression in vivo: correlation with glucocorticoid- and developmentally regulated expression. Molecular Carcinogenesis. 10: 189-98. PMID 8068179 DOI: 10.1002/Mc.2940100403  0.471
1993 Hamilton JW, Louis CA, Doherty KA, Hunt SR, Reed MJ, Treadwell MD. Preferential alteration of inducible gene expression in vivo by carcinogens that induce bulky DNA lesions. Molecular Carcinogenesis. 8: 34-43. PMID 7688968 DOI: 10.1002/Mc.2940080109  0.473
1992 Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes. Archives of Biochemistry and Biophysics. 298: 96-104. PMID 1524447 DOI: 10.1016/0003-9861(92)90099-I  0.69
1991 Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Archives of Biochemistry and Biophysics. 289: 387-92. PMID 1898078 DOI: 10.1016/0003-9861(91)90428-L  0.671
1991 Mackie JE, Back DW, Hamilton JW, Marks GS. Elevation of delta-aminolevulinic acid synthase and cytochrome PB1 P450 messenger RNA levels by dihydropyridines, dihydroquinolines, sydnones, and N-ethylprotoporphyrin IX. Biochemical Pharmacology. 42: 475-83. PMID 1859461 DOI: 10.1016/0006-2952(91)90308-R  0.338
1989 Qureshi MA, Bloom SE, Hamilton JW, Dietert RR. Toxic effects of methyl methanesulfonate (MMS) on activated macrophages from chickens. Environmental and Molecular Mutagenesis. 13: 253-62. PMID 2707255 DOI: 10.1002/Em.2850130309  0.549
1989 Hamilton JW, Wetterhahn KE. Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium(VI)-induced DNA damage Molecular Carcinogenesis. 2: 274-286. PMID 2604865 DOI: 10.1002/Mc.2940020508  0.707
1989 Denison MS, Hamilton JW, Young CM, Wilkinson CF. Nickel and nickel-conjugate metabolism and acute toxicity. Veterinary and Human Toxicology. 31: 498-9. PMID 2603369  0.464
1989 Wetterhahn KE, Hamilton JW. Molecular basis of hexavalent chromium carcinogenicity: effect on gene expression. The Science of the Total Environment. 86: 113-29. PMID 2602931 DOI: 10.1016/0048-9697(89)90199-X  0.7
1989 Wetterhahn KE, Hamilton JW, Aiyar J, Borges KM, Floyd R. Mechanism of chromium(VI) carcinogenesis. Reactive intermediates and effect on gene expression. Biological Trace Element Research. 21: 405-11. PMID 2484620 DOI: 10.1007/Bf02917282  0.675
1988 Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Wetterhahn KE. Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem Biochemical Journal. 255: 267-275. PMID 3196319 DOI: 10.1042/Bj2570936  0.663
1986 Hamilton JW, Wetterhahn KE. Chromium (vi)-induced dna damage in chick embryo liver and blood cells in vivo Carcinogenesis. 7: 2085-2088. PMID 3779902 DOI: 10.1093/Carcin/7.12.2085  0.666
1986 Hamilton JW, Bloom SE. Correlation between induction of xenobiotic metabolism and DNA damage from chemical carcinogens in the chick embryo in vivo. Carcinogenesis. 7: 1101-6. PMID 3087644 DOI: 10.1093/Carcin/7.7.1101  0.584
1986 Denison MS, Okey AB, Hamilton JW, Bloom SE, Wilkinson CF. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. Journal of Biochemical Toxicology. 1: 39-49. PMID 2856072 DOI: 10.1002/Jbt.2570010305  0.674
1985 Denison MS, Hamilton JW, Wilkinson CF. Comparative studies of aryl hydrocarbon hydroxylase and the Ah receptor in nonmammalian species. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 80: 319-24. PMID 2861016 DOI: 10.1016/0742-8413(85)90063-5  0.558
1985 Hamilton JW, Bloom SE. Correlation between mixed-function oxidase enzyme induction and genotoxicity, in vivo Federation Proceedings. 44: No. 533.  0.476
1984 Hamilton JW, Bloom SE. Correlation between mixed-function oxidase enzyme induction and aflatoxin B1-induced unscheduled DNA synthesis in the chick embryo, in vivo. Environmental Mutagenesis. 6: 41-8. PMID 6420149 DOI: 10.1002/Em.2860060106  0.581
1984 Hamilton JW, Denison MS, Bloom SE, Wilkinson CF. Ontogeny of the cytosolic TCDD receptor in the chick embryo and neonate Federation Proceedings. 43: no. 1708.  0.634
1983 Hamilton JW, Bloom SE. Developmental differences in basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in chick embryo liver and lung in ovo. Biochemical Pharmacology. 32: 2986-8. PMID 6626269 DOI: 10.1016/0006-2952(83)90409-4  0.533
1983 Hamilton JW, Denison MS, Bloom SE. Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo. Proceedings of the National Academy of Sciences of the United States of America. 80: 3372-6. PMID 6407011 DOI: 10.1073/Pnas.80.11.3372  0.55
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