| Year |
Citation |
Score |
| 2021 |
Zheng W, Tasselli L, Li TM, Chua KF. Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation. Genes. 12. PMID 34573442 DOI: 10.3390/genes12091460 |
0.343 |
|
| 2020 |
Chua KF. Chromatin Regulation and Genome Maintenance by Mammalian SIRT6 and SIRT7 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00152 |
0.35 |
|
| 2020 |
Chua K. Sirtuins: New Roles for Sirtuins in Aging and Disease Innovation in Aging. 4: 741-741. DOI: 10.1093/geroni/igaa057.2650 |
0.322 |
|
| 2019 |
You W, Zheng W, Weiss S, Chua KF, Steegborn C. Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives. Scientific Reports. 9: 19176. PMID 31844103 DOI: 10.1038/S41598-019-55654-1 |
0.335 |
|
| 2019 |
Wang WW, Angulo-Ibanez M, Lyu J, Kurra Y, Tong Z, Wu B, Zhang L, Sharma V, Zhou J, Lin H, Gao YQ, Li W, Chua KF, Liu WR. A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. Journal of the American Chemical Society. PMID 30653310 DOI: 10.1021/Jacs.8B12083 |
0.435 |
|
| 2018 |
Paredes S, Angulo-Ibanez M, Tasselli L, Carlson SM, Zheng W, Li TM, Chua KF. The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. The Journal of Biological Chemistry. PMID 29728458 DOI: 10.1074/Jbc.Ac118.003325 |
0.48 |
|
| 2016 |
You W, Rotili D, Li TM, Kambach C, Meleshin M, Schutkowski M, Chua KF, Mai A, Steegborn C. Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules. Angewandte Chemie (International Ed. in English). PMID 27990725 DOI: 10.1002/Anie.201610082 |
0.327 |
|
| 2016 |
Tasselli L, Zheng W, Chua KF. SIRT6: Novel Mechanisms and Links to Aging and Disease. Trends in Endocrinology and Metabolism: Tem. PMID 27836583 DOI: 10.1016/J.Tem.2016.10.002 |
0.416 |
|
| 2016 |
Paredes S, Chua KF. SIRT7 clears the way for DNA repair. The Embo Journal. PMID 27302089 DOI: 10.15252/Embj.201694904 |
0.407 |
|
| 2016 |
Tasselli L, Xi Y, Zheng W, Tennen RI, Odrowaz Z, Simeoni F, Li W, Chua KF. SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence. Nature Structural & Molecular Biology. PMID 27043296 DOI: 10.1038/Nsmb.3202 |
0.464 |
|
| 2016 |
Fang EF, Scheibye-Knudsen M, Chua KF, Mattson MP, Croteau DL, Bohr VA. Nuclear DNA damage signalling to mitochondria in ageing. Nature Reviews. Molecular Cell Biology. PMID 26956196 DOI: 10.1038/Nrm.2016.14 |
0.331 |
|
| 2015 |
Malik S, Villanova L, Tanaka S, Aonuma M, Roy N, Berber E, Pollack JR, Michishita-Kioi E, Chua KF. SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors. Scientific Reports. 5: 9841. PMID 25923013 DOI: 10.1038/Srep09841 |
0.306 |
|
| 2015 |
Tasselli L, Chua KF. Methylation gets into rhythm with NAD(+)-SIRT1. Nature Structural & Molecular Biology. 22: 275-7. PMID 25837871 DOI: 10.1038/Nsmb.3004 |
0.345 |
|
| 2014 |
Paredes S, Villanova L, Chua KF. Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1741-6. PMID 24536059 DOI: 10.1158/1078-0432.Ccr-13-1547 |
0.366 |
|
| 2013 |
Simeoni F, Tasselli L, Tanaka S, Villanova L, Hayashi M, Kubota K, Isono F, Garcia BA, Michishita-Kioi E, Chua KF. Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling. Scientific Reports. 3: 3085. PMID 24169447 DOI: 10.1038/Srep03085 |
0.381 |
|
| 2013 |
Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. The Journal of Biological Chemistry. 288: 18439-47. PMID 23653361 DOI: 10.1074/Jbc.M112.405928 |
0.41 |
|
| 2013 |
Moore KE, Carlson SM, Camp ND, Cheung P, James RG, Chua KF, Wolf-Yadlin A, Gozani O. A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation. Molecular Cell. 50: 444-56. PMID 23583077 DOI: 10.1016/J.Molcel.2013.03.005 |
0.343 |
|
| 2012 |
Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 487: 114-8. PMID 22722849 DOI: 10.1038/Nature11043 |
0.422 |
|
| 2011 |
Tennen RI, Bua DJ, Wright WE, Chua KF. SIRT6 is required for maintenance of telomere position effect in human cells. Nature Communications. 2: 433. PMID 21847107 DOI: 10.1038/Ncomms1443 |
0.447 |
|
| 2011 |
Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, et al. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nature Immunology. 12: 29-36. PMID 21131967 DOI: 10.1038/Ni.1968 |
0.401 |
|
| 2011 |
Tennen RI, Chua KF. Chromatin regulation and genome maintenance by mammalian SIRT6. Trends in Biochemical Sciences. 36: 39-46. PMID 20729089 DOI: 10.1016/J.Tibs.2010.07.009 |
0.43 |
|
| 2010 |
Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, et al. Dietary restriction: standing up for sirtuins. Science (New York, N.Y.). 329: 1012-3; author reply. PMID 20798296 DOI: 10.1126/Science.329.5995.1012 |
0.329 |
|
| 2010 |
Tennen RI, Berber E, Chua KF. Functional dissection of SIRT6: identification of domains that regulate histone deacetylase activity and chromatin localization. Mechanisms of Ageing and Development. 131: 185-92. PMID 20117128 DOI: 10.1016/J.Mad.2010.01.006 |
0.422 |
|
| 2009 |
McCord RA, Michishita E, Hong T, Berber E, Boxer LD, Kusumoto R, Guan S, Shi X, Gozani O, Burlingame AL, Bohr VA, Chua KF. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging. 1: 109-21. PMID 20157594 DOI: 10.18632/Aging.100011 |
0.363 |
|
| 2009 |
Michishita E, McCord RA, Boxer LD, Barber MF, Hong T, Gozani O, Chua KF. Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle (Georgetown, Tex.). 8: 2664-6. PMID 19625767 DOI: 10.4161/Cc.8.16.9367 |
0.443 |
|
| 2009 |
Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, Chua KF. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62-74. PMID 19135889 DOI: 10.1016/J.Cell.2008.10.052 |
0.363 |
|
| 2008 |
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/Nature06736 |
0.449 |
|
| 2008 |
Zhang Y, Kwon S, Yamaguchi T, Cubizolles F, Rousseaux S, Kneissel M, Cao C, Li N, Cheng HL, Chua K, Lombard D, Mizeracki A, Matthias G, Alt FW, Khochbin S, et al. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Molecular and Cellular Biology. 28: 1688-701. PMID 18180281 DOI: 10.1128/Mcb.01154-06 |
0.379 |
|
| 2006 |
Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, ... ... Chua KF, et al. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. 442: 96-9. PMID 16728974 DOI: 10.1038/Nature04835 |
0.407 |
|
| 2006 |
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell. 124: 315-29. PMID 16439206 DOI: 10.1016/J.Cell.2005.11.044 |
0.444 |
|
| 2005 |
Chua KF, Mostoslavsky R, Lombard DB, Pang WW, Saito S, Franco S, Kaushal D, Cheng HL, Fischer MR, Stokes N, Murphy MM, Appella E, Alt FW. Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metabolism. 2: 67-76. PMID 16054100 DOI: 10.1016/J.Cmet.2005.06.007 |
0.356 |
|
| 2005 |
Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW. DNA repair, genome stability, and aging. Cell. 120: 497-512. PMID 15734682 DOI: 10.1016/J.Cell.2005.01.028 |
0.36 |
|
| 2004 |
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (New York, N.Y.). 303: 2011-5. PMID 14976264 DOI: 10.1126/Science.1094637 |
0.356 |
|
| 2003 |
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10794-9. PMID 12960381 DOI: 10.1073/Pnas.1934713100 |
0.362 |
|
| 2003 |
Bassing CH, Suh H, Ferguson DO, Chua KF, Manis J, Eckersdorff M, Gleason M, Bronson R, Lee C, Alt FW. Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors. Cell. 114: 359-70. PMID 12914700 DOI: 10.1016/S0092-8674(03)00566-X |
0.338 |
|
| 2003 |
Chaudhuri J, Tian M, Khuong C, Chua K, Pinaud E, Alt FW. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature. 422: 726-30. PMID 12692563 DOI: 10.1038/Nature01574 |
0.372 |
|
| 2003 |
Shinkura R, Tian M, Smith M, Chua K, Fujiwara Y, Alt FW. The influence of transcriptional orientation on endogenous switch region function. Nature Immunology. 4: 435-41. PMID 12679811 DOI: 10.1038/Ni918 |
0.307 |
|
| 2002 |
Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, Monroe BC, Ciccone DN, Yan C, Vlasakova K, Livingston DM, Ferguson DO, Scully R, Alt FW. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proceedings of the National Academy of Sciences of the United States of America. 99: 8173-8. PMID 12034884 DOI: 10.1073/Pnas.122228699 |
0.365 |
|
| 2001 |
Chua K, Reed R. An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing Molecular and Cellular Biology. 21: 1509-1514. PMID 11238888 DOI: 10.1128/Mcb.21.5.1509-1514.2001 |
0.492 |
|
| 1999 |
Chua K, Reed R. The RNA splicing factor hSlu7 is required for correct 3' splice-site choice Nature. 402: 207-210. PMID 10647016 DOI: 10.1038/46086 |
0.497 |
|
| 1999 |
Chua K, Reed R. Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing Genes and Development. 13: 841-850. PMID 10197984 DOI: 10.1101/Gad.13.7.841 |
0.484 |
|
| 1998 |
Seghezzi W, Chua K, Shanahan F, Gozani O, Reed R, Lees E. Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells Molecular and Cellular Biology. 18: 4526-4536. PMID 9671462 DOI: 10.1128/Mcb.18.8.4526 |
0.495 |
|
| 1998 |
Wang C, Chua K, Seghezzi W, Lees E, Gozani O, Reed R. Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis Genes and Development. 12: 1409-1414. PMID 9585501 DOI: 10.1101/Gad.12.10.1409 |
0.511 |
|
| 1997 |
Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC. Cell. 89: 781-7. PMID 9182766 DOI: 10.1016/S0092-8674(00)80261-5 |
0.472 |
|
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